General Information of the Compound
Compound ID
CP0921833
Compound Name
exo-tert-butyl 4-(3-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)propyl)-4-phenylpiperidine-1-carboxylate
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Formula
C34H46N4O2
Molecular Weight
542.768
Canonical SMILES
Cc1nc2ccccc2n1[C@H]1C[C@H]2CC[C@@H](C1)N2CCCC1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1
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InChI
InChI=1S/C34H46N4O2/c1-25-35-30-13-8-9-14-31(30)38(25)29-23-27-15-16-28(24-29)37(27)20-10-17-34(26-11-6-5-7-12-26)18-21-36(22-19-34)32(39)40-33(2,3)4/h5-9,11-14,27-29H,10,15-24H2,1-4H3/t27-,28+,29+
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InChIKey
WFKINWNQILYNCH-WLNZHLEZSA-N
Physicochemical Property
logP
7.26172
Rotatable Bonds
6
Heavy Atom Count
40
Polar Areas
50.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL3084487
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 31622.78 nM
   TI
   LI
   LO
   TS