General Information of the Compound
Compound ID
CP0387345
Compound Name
1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-ethyl-N-phenylpiperidine-4-carboxamide
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Structure
Formula
C31H41ClN4O3
Molecular Weight
553.147
Canonical SMILES
CCN(C(=O)C1CCN(CCCN(C(=O)C2CCN(CC2)C(C)=O)c2cccc(Cl)c2)CC1)c1ccccc1
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InChI
InChI=1S/C31H41ClN4O3/c1-3-35(28-10-5-4-6-11-28)30(38)25-13-19-33(20-14-25)17-8-18-36(29-12-7-9-27(32)23-29)31(39)26-15-21-34(22-16-26)24(2)37/h4-7,9-12,23,25-26H,3,8,13-22H2,1-2H3
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InChIKey
PZASBFFWOJWAEO-UHFFFAOYSA-N
Physicochemical Property
logP
5.0867
Rotatable Bonds
9
Heavy Atom Count
39
Polar Areas
64.17
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76321110
ChEMBL ID
CHEMBL3104687
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS