General Information of the Compound
Compound ID
CP0503044
Compound Name
1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-1-ethyl-3-methylurea
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Structure
Formula
C26H38N4O3S
Molecular Weight
486.682
Canonical SMILES
CCN(C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1)C(=O)NC
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InChI
InChI=1S/C26H38N4O3S/c1-4-30(26(31)27-2)24-16-19-29(20-17-24)18-15-23(22-11-7-5-8-12-22)21-28(3)34(32,33)25-13-9-6-10-14-25/h5-14,23-24H,4,15-21H2,1-3H3,(H,27,31)
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InChIKey
LNVYOJZDFJEMLZ-UHFFFAOYSA-N
Physicochemical Property
logP
3.6067
Rotatable Bonds
10
Heavy Atom Count
34
Polar Areas
72.96
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 486608
ChEMBL ID
CHEMBL84268
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 120 nM
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