General Information of the Compound
Compound ID
CP0522275
Compound Name
(R)-N-ethyl-N-(1-(3-(3-isopropylphenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
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Structure
Formula
C35H46N2O5S2
Molecular Weight
638.896
Canonical SMILES
CCN(C1CCN(CC[C@H](c2ccc(cc2)S(C)(=O)=O)c2cccc(c2)C(C)C)CC1)C(=O)Cc1ccc(cc1)S(C)(=O)=O
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InChI
InChI=1S/C35H46N2O5S2/c1-6-37(35(38)24-27-10-14-32(15-11-27)43(4,39)40)31-18-21-36(22-19-31)23-20-34(30-9-7-8-29(25-30)26(2)3)28-12-16-33(17-13-28)44(5,41)42/h7-17,25-26,31,34H,6,18-24H2,1-5H3/t34-/m1/s1
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InChIKey
BDQQVPFAZDRHQD-UUWRZZSWSA-N
Physicochemical Property
logP
5.6946
Rotatable Bonds
12
Heavy Atom Count
44
Polar Areas
91.83
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
44

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16073672
ChEMBL ID
CHEMBL382436
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 110 nM
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