| Compound ID |
Compound Name |
Compound Formula |
|
CP0436335
|
(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-fluoropurin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C26H27FN6O4
|
1
|
| 1 |
EC50 = 0.85 nM
|
|
|
|
CP0442213
|
(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-methoxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C22H28N10O5
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0391247
|
(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-bromo-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H25BrN10O4
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0410251
|
(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-fluoropurin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C25H25FN6O4
|
1
|
| 1 |
EC50 = 2.02 nM
|
|
|
|
CP0041258
|
(CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmethyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-ylamino]-ethyl}-phenyl)-propionic acid
Show/Hide
|
C23H29N7O6
|
3
|
| 1 |
EC50 = 2.12 nM
|
|
|
| 2 |
EC50 = 18.47 nM
|
|
|
| 3 |
Ki = 12.48 nM
|
|
|
|
CP0871190
|
2-[1-(R)-Methyl-2-(4-methoxyphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C22H28N10O4
|
2
|
| 1 |
EC50 = 2.2 nM
|
|
|
| 2 |
EC50 = 3 nM
|
|
|
|
CP0397901
|
(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C12H15N9O3
|
2
|
| 1 |
EC50 = 2.36 nM
|
|
|
| 2 |
Ki = 8.12 nM
|
|
|
|
CP0389281
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C19H20IN9O3
|
2
|
| 1 |
EC50 = 2.87 nM
|
|
|
| 2 |
Ki = 16.8 nM
|
|
|
|
CP0432866
|
(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-nitro-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H25N11O6
|
1
|
| 1 |
EC50 = 3.1 nM
|
|
|
|
CP0381985
|
(2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C12H14ClN9O3
|
2
|
| 1 |
EC50 = 3.84 nM
|
|
|
| 2 |
Ki = 20.7 nM
|
|
|
|
CP0403558
|
(2R,3R,4S,5R)-2-[6-amino-2-[1-(4-methoxyphenyl)propan-2-ylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C22H28N10O4
|
1
|
| 1 |
EC50 = 4.1 nM
|
|
|
|
CP0408567
|
(2R,3R,4S,5R)-2-[6-[(3-bromophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H20BrN9O3
|
2
|
| 1 |
EC50 = 4.46 nM
|
|
|
| 2 |
Ki = 24.5 nM
|
|
|
|
CP0418022
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-chloro-2-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H31ClFN9O4
|
2
|
| 1 |
EC50 = 4.89 nM
|
|
|
| 2 |
Ki = 4.78 nM
|
|
|
|
CP0398202
|
(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopropylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C15H18ClN9O3
|
4
|
| 1 |
EC50 = 5.31 nM
|
|
|
| 2 |
EC50 = 21.5 nM
|
|
|
| 3 |
Ki = 62.2 nM
|
|
|
| 4 |
Ki = 274 nM
|
|
|
|
CP0869243
|
2-[1-(R,S)-Methyl-2-phenylethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C21H26N10O3
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
|
CP0410248
|
(2S,3S,4R,5R)-5-(6-amino-2-fluoropurin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C12H15FN6O4
|
1
|
| 1 |
EC50 = 5.6 nM
|
|
|
|
CP0398223
|
[4-[3-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoylamino]-2-nitrophenyl] acetate
Show/Hide
|
C31H35N9O9
|
1
|
| 1 |
EC50 = 5.86 nM
|
|
|
|
CP0416329
|
(2S,3S,4R,5R)-5-[2-[2-(4-aminophenyl)ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C34H38N8O4
|
1
|
| 1 |
EC50 = 6.3 nM
|
|
|
|
CP0410250
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[5-[(3S)-dithiolan-3-yl]pentanoylamino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C28H38N8O5S2
|
1
|
| 1 |
EC50 = 6.6 nM
|
|
|
|
CP0389279
|
(2R,3R,4S,5R)-2-[6-[(3-chlorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H20ClN9O3
|
2
|
| 1 |
EC50 = 6.71 nM
|
|
|
| 2 |
Ki = 29.8 nM
|
|
|
|
CP0397895
|
(2R,3R,4S,5R)-2-[6-[[(1R,2S,4R)-2-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H25N9O3
|
2
|
| 1 |
EC50 = 7.71 nM
|
|
|
| 2 |
Ki = 64.5 nM
|
|
|
|
CP0391229
|
(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-(4-hydroxy-phenyl)-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H26N10O5
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0398200
|
(2R,3R,4S,5R)-2-[6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C18H17ClFN9O3
|
2
|
| 1 |
EC50 = 8.4 nM
|
|
|
| 2 |
Ki = 77.5 nM
|
|
|
|
CP0057366
|
(2R,3R,4S,5R)-2-(6-amino-2-((S)-1-hydroxy-3-phenylpropan-2-ylamino)-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diol
Show/Hide
|
C21H26N10O4
|
1
|
| 1 |
EC50 = 8.8 nM
|
|
|
|
CP0397900
|
(2R,3R,4S,5R)-2-[2-chloro-6-[(2-iodophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H19ClIN9O3
|
2
|
| 1 |
EC50 = 9.04 nM
|
|
|
| 2 |
Ki = 108 nM
|
|
|
|
CP0860199
|
2-[1-(R,S)-Methyl-2-(4-fluorophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C21H25FN10O3
|
1
|
| 1 |
EC50 = 9.6 nM
|
|
|
|
CP0396254
|
(2R,3R,4S,5R)-2-[6-(cyclopropylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C15H19N9O3
|
4
|
| 1 |
EC50 = 9.75 nM
|
|
|
| 2 |
EC50 = 21.6 nM
|
|
|
| 3 |
Ki = 93 nM
|
|
|
| 4 |
Ki = 146 nM
|
|
|
|
CP0199236
|
(2R,3R,4S,5R)-2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C16H21N5O4
|
2
|
| 1 |
EC50 = 10 nM
|
|
|
| 2 |
Ki = 5.7 nM
|
|
|
|
CP0452793
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2,3-difluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H31F2N9O4
|
2
|
| 1 |
EC50 = 10.16 nM
|
|
|
| 2 |
Ki = 5.48 nM
|
|
|
|
CP0851744
|
4-((4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenoxy)methyl)benzenesulfonic acid, ammonia salt
Show/Hide
|
C26H26N8O5S
|
1
|
| 1 |
EC50 = 10.2 nM
|
|
|
|
CP0847457
|
2-[1-(S)-Methyl-2-(4-methoxyphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C22H28N10O4
|
1
|
| 1 |
EC50 = 10.6 nM
|
|
|
|
CP0850598
|
2-[1-(R,S)-Methyl-2-(4-chlorophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C21H25ClN10O3
|
1
|
| 1 |
EC50 = 10.6 nM
|
|
|
|
CP0448233
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32FN9O4
|
2
|
| 1 |
EC50 = 11.87 nM
|
|
|
| 2 |
Ki = 7.76 nM
|
|
|
|
CP0199235
|
(2R,3R,4S)-2-(6-amino-2-(hex-1-ynyl)-9H-purin-9-yl)tetrahydrothiophene-3,4-diol
Show/Hide
|
C15H19N5O2S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0433025
|
(2S,3S,4R,5R)-5-[6-amino-2-(2-phenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C20H25N7O4
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C12H16N6O4
|
19
|
| 1 |
EC50 = 12.58 nM
|
|
|
| 2 |
EC50 = 17.38 nM
|
|
|
| 3 |
EC50 = 18 nM
|
|
|
| 4 |
EC50 = 21.9 nM
|
|
|
| 5 |
EC50 = 40 nM
|
|
|
| 6 |
EC50 = 45 nM
|
|
|
| 7 |
EC50 = 50 nM
|
|
|
| 8 |
Ki = 1.5 nM
|
|
|
| 9 |
Ki = 2.2 nM
|
|
|
| 10 |
Ki = 8.41 nM
|
|
|
| 11 |
Ki = 12.2 nM
|
|
|
| 12 |
Ki = 12.4 nM
|
|
|
| 13 |
Ki = 12.5 nM
|
|
|
| 14 |
Ki = 16 nM
|
|
|
| 15 |
Ki = 19.1 nM
|
|
|
| 16 |
Ki = 20 nM
|
|
|
| 17 |
Ki = 21.4 nM
|
|
|
| 18 |
Ki = 24.6 nM
|
|
|
| 19 |
Ki = 29.2 nM
|
|
|
|
CP0397903
|
(2R,3R,4S,5R)-2-[6-[[(1R,2S,4R)-2-bicyclo[2.2.1]heptanyl]amino]-2-chloropurin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H24ClN9O3
|
2
|
| 1 |
EC50 = 12.8 nM
|
|
|
| 2 |
Ki = 164 nM
|
|
|
|
CP0404606
|
(2R,3R,4S,5R)-2-[6-[(3-bromophenyl)methylamino]-2-chloropurin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H19BrClN9O3
|
2
|
| 1 |
EC50 = 13.3 nM
|
|
|
| 2 |
Ki = 58.2 nM
|
|
|
|
CP0433027
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-aminophenyl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C20H26N8O4
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0436337
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C35H46N8O6
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0408454
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-[(3-fluorophenyl)methylamino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C19H20FN9O3
|
2
|
| 1 |
EC50 = 14.4 nM
|
|
|
| 2 |
Ki = 74 nM
|
|
|
|
CP0396249
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(thiophen-2-ylmethylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C17H19N9O3S
|
2
|
| 1 |
EC50 = 14.7 nM
|
|
|
| 2 |
Ki = 98.4 nM
|
|
|
|
CP0437252
|
(2R,3R,4S,5R)-2-[2-chloro-6-[(3-chlorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H19Cl2N9O3
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
Ki = 110 nM
|
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|
|
CP0396248
|
(2R,3R,4S,5R)-2-[6-(cyclopropylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C16H21N9O3
|
2
|
| 1 |
EC50 = 16.6 nM
|
|
|
| 2 |
Ki = 112 nM
|
|
|
|
CP0874282
|
2-[1-(R,S)-Methyl-2-(4-trifluoromethylphenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C22H25F3N10O3
|
1
|
| 1 |
EC50 = 19.6 nM
|
|
|
|
CP0474416
|
(2R,3R,4S)-2-(6-amino-2-((E)-hex-1-enyl)-9H-purin-9-yl)tetrahydrothiophene-3,4-diol
Show/Hide
|
C15H21N5O2S
|
1
|
| 1 |
EC50 = 20.6 nM
|
|
|
|
CP0039632
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-cyclopropyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C13H16N6O4
|
1
|
| 1 |
EC50 = 22.9 nM
|
|
|
|
CP0398108
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32ClN9O4
|
2
|
| 1 |
EC50 = 24 nM
|
|
|
| 2 |
Ki = 18.21 nM
|
|
|
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CP0398201
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(oxolan-2-ylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C16H21N9O4
|
2
|
| 1 |
EC50 = 25.1 nM
|
|
|
| 2 |
Ki = 554 nM
|
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CP0211418
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-cyclobutyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C14H18N6O4
|
1
|
| 1 |
EC50 = 26.8 nM
|
|
|
|
CP0452795
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-(3-phenylpropoxy)phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C31H38N8O5
|
2
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
Ki = 16.32 nM
|
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|
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CP0408566
|
(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopropylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C16H20ClN9O3
|
2
|
| 1 |
EC50 = 28.6 nM
|
|
|
| 2 |
Ki = 329 nM
|
|
|
|
CP0398203
|
(2R,3R,4S,5R)-2-[2-chloro-6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C18H16Cl2FN9O3
|
2
|
| 1 |
EC50 = 28.8 nM
|
|
|
| 2 |
Ki = 223 nM
|
|
|
|
CP0491323
|
(2S,3S,4R,5R)-5-[2-[2-(4-bromophenyl)ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C34H36BrN7O4
|
1
|
| 1 |
EC50 = 30.9 nM
|
|
|
|
CP0418021
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32ClN9O4
|
2
|
| 1 |
EC50 = 31 nM
|
|
|
| 2 |
Ki = 25 nM
|
|
|
|
CP0849803
|
2-[1-(R,S)-Methyl-2-(4-bromophenyl)ethylamino]-5'-(2-ethyl-2H-tetrazol-5-yl)adenosine
Show/Hide
|
C21H25BrN10O3
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0404609
|
(2R,3R,4S,5R)-2-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H19ClFN9O3
|
2
|
| 1 |
EC50 = 31.3 nM
|
|
|
| 2 |
Ki = 242 nM
|
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CP0384690
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(2R,3R,4S,5R)-2-[2-chloro-6-(oxolan-2-ylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C16H20ClN9O4
|
2
|
| 1 |
EC50 = 33.2 nM
|
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| 2 |
Ki = 870 nM
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CP0399646
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-nitrophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32N10O6
|
2
|
| 1 |
EC50 = 36 nM
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| 2 |
Ki = 24 nM
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CP0397950
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H31Cl2N9O4
|
2
|
| 1 |
EC50 = 38 nM
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|
|
| 2 |
Ki = 26 nM
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CP0399650
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C30H33F3N8O5
|
2
|
| 1 |
EC50 = 38 nM
|
|
|
| 2 |
Ki = 24 nM
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CP0452791
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4-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]benzoic acid
Show/Hide
|
C25H33N9O6
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2
|
| 1 |
EC50 = 38 nM
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|
|
| 2 |
Ki = 30 nM
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CP0389280
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(2R,3R,4S,5R)-2-[2-chloro-6-(thiophen-2-ylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C17H18ClN9O3S
|
2
|
| 1 |
EC50 = 38.4 nM
|
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|
| 2 |
Ki = 286 nM
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CP0383509
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(6-bromo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C20H21BrN6O5
|
2
|
| 1 |
EC50 = 39.7 nM
|
|
|
| 2 |
Ki = 150 nM
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CP0404600
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(2R,3R,4S,5R)-2-[6-[(4-chloro-2-fluorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H19ClFN9O3
|
2
|
| 1 |
EC50 = 40.7 nM
|
|
|
| 2 |
Ki = 252 nM
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CP0398112
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(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3-chloro-4-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H31ClFN9O4
|
2
|
| 1 |
EC50 = 41 nM
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|
|
| 2 |
Ki = 34 nM
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CP0416328
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(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-bromophenyl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C20H24BrN7O4
|
1
|
| 1 |
EC50 = 42 nM
|
|
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|
CP0398115
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-bromophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32BrN9O4
|
2
|
| 1 |
EC50 = 43 nM
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|
|
| 2 |
Ki = 29 nM
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CP0410249
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[(3,5-ditert-butylbenzoyl)amino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C35H46N8O5
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0448235
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32ClN9O4
|
2
|
| 1 |
EC50 = 46 nM
|
|
|
| 2 |
Ki = 23 nM
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|
CP0448234
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H32F3N9O4
|
2
|
| 1 |
EC50 = 47 nM
|
|
|
| 2 |
Ki = 36 nM
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CP0448236
|
2-[4-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]-3-bromophenyl]acetic acid
Show/Hide
|
C26H34BrN9O6
|
2
|
| 1 |
EC50 = 48 nM
|
|
|
| 2 |
Ki = 24 nM
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|
CP0847458
|
2-(1-Methyl-2-phenylethylamino)adenosine
Show/Hide
|
C19H24N6O4
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0471056
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-[(4-chlorophenyl)methoxy]phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C29H33ClN8O5
|
2
|
| 1 |
EC50 = 52 nM
|
|
|
| 2 |
Ki = 33 nM
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|
CP0399648
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(3,5-dichlorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H31Cl2N9O4
|
2
|
| 1 |
EC50 = 53 nM
|
|
|
| 2 |
Ki = 33 nM
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CP0408565
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(furan-2-ylmethylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C17H19N9O4
|
2
|
| 1 |
EC50 = 54.3 nM
|
|
|
| 2 |
Ki = 342 nM
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|
|
CP0404601
|
(2R,3R,4S,5R)-2-[2-chloro-6-(furan-2-ylmethylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C17H18ClN9O4
|
2
|
| 1 |
EC50 = 60.2 nM
|
|
|
| 2 |
Ki = 663 nM
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|
|
|
CP0399647
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H35N9O5
|
2
|
| 1 |
EC50 = 62 nM
|
|
|
| 2 |
Ki = 43 nM
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|
|
|
CP0433028
|
(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-(2-phenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C34H37N7O4
|
1
|
| 1 |
EC50 = 66 nM
|
|
|
|
CP0399651
|
ethyl 2-[4-[4-[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]piperazin-1-yl]phenoxy]acetate
Show/Hide
|
C26H34N8O7
|
2
|
| 1 |
EC50 = 74 nM
|
|
|
| 2 |
Ki = 52 nM
|
|
|
|
CP0391375
|
(2R,3R,4R)-2-(6-amino-2-hex-1-ynylpurin-9-yl)oxolane-3,4-diol
Show/Hide
|
C15H19N5O3
|
1
|
| 1 |
EC50 = 80.3 nM
|
|
|
|
CP0399664
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C27H39N9O6
|
2
|
| 1 |
EC50 = 84 nM
|
|
|
| 2 |
Ki = 56 nM
|
|
|
|
CP0436339
|
(2S,3S,4R,5R)-5-[6-(2,2-diphenylethylamino)-2-[2-[4-[5-[(3S)-dithiolan-3-yl]pentanoylamino]phenyl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C42H50N8O5S2
|
1
|
| 1 |
EC50 = 89.7 nM
|
|
|
|
CP0448231
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-phenylpiperazin-1-yl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H33N9O4
|
2
|
| 1 |
EC50 = 91 nM
|
|
|
| 2 |
Ki = 55 nM
|
|
|
|
CP0452792
|
3-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]benzoic acid
Show/Hide
|
C25H33N9O6
|
2
|
| 1 |
EC50 = 95 nM
|
|
|
| 2 |
Ki = 72 nM
|
|
|
|
CP0389278
|
(2R,3R,4S,5R)-2-[2-chloro-6-[(4-chloro-2-fluorophenyl)methylamino]purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C19H18Cl2FN9O3
|
2
|
| 1 |
EC50 = 96.5 nM
|
|
|
| 2 |
Ki = 881 nM
|
|
|
|
CP0372684
|
(2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-chloro-phenyl)-1-hydroxymethyl-ethylamino]-purin-9-yl}-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C21H25ClN10O4
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0448232
|
2-[4-[4-[2-[[6-amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]amino]ethyl]piperazin-1-yl]phenyl]acetic acid
Show/Hide
|
C26H35N9O6
|
2
|
| 1 |
EC50 = 103 nM
|
|
|
| 2 |
Ki = 84 nM
|
|
|
|
CP0441596
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-methylphenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H35N9O4
|
2
|
| 1 |
EC50 = 112 nM
|
|
|
| 2 |
Ki = 88 nM
|
|
|
|
CP0398114
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H32F3N9O4
|
2
|
| 1 |
EC50 = 127 nM
|
|
|
| 2 |
Ki = 95 nM
|
|
|
|
CP0851743
|
(E)-N-(4-(2-(4-(3-(5-Amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7yl)propyl)phenoxy)acetamido)butyl)-6-(2-(4-(2-(5,5-difluoro-7-(thiophen-2-yl)-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)vinyl)phenoxy)acetamido)hexanamide
Show/Hide
|
C54H55BF2N12O6S
|
1
|
| 1 |
EC50 = 128 nM
|
|
|
|
CP0397951
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32FN9O4
|
2
|
| 1 |
EC50 = 145 nM
|
|
|
| 2 |
Ki = 98 nM
|
|
|
|
CP0398111
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(4-iodophenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C24H32IN9O4
|
2
|
| 1 |
EC50 = 156 nM
|
|
|
| 2 |
Ki = 92 nM
|
|
|
|
CP0855184
|
3-(4-(2-(6-(4-(9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-ylamino)butylamino)-6-oxohexylamino)-2-oxoethoxy)styryl)-5,5-difluoro-7-(thiophen-2-yl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide
Show/Hide
|
C45H51BF2N10O7S
|
1
|
| 1 |
EC50 = 173.78 nM
|
|
|
|
CP0379088
|
(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-N-cyclopentyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C15H20N6O4
|
1
|
| 1 |
EC50 = 225 nM
|
|
|
|
CP0397896
|
(2R,3R,4S,5R)-2-[2-chloro-6-(methylamino)purin-9-yl]-5-(2-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
|
C13H16ClN9O3
|
2
|
| 1 |
EC50 = 238 nM
|
|
|
| 2 |
Ki = 3350 nM
|
|
|
|
CP0373160
|
9-(4-hydroxyphenethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
|
C18H21N5O3
|
2
|
| 1 |
EC50 = 302 nM
|
|
|
| 2 |
Ki = 630 nM
|
|
|
|
CP0436338
|
(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butylbenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C49H58N8O5
|
1
|
| 1 |
EC50 = 366 nM
|
|
|
|
CP0398113
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H35N9O5
|
2
|
| 1 |
EC50 = 393 nM
|
|
|
| 2 |
Ki = 277 nM
|
|
|
|
CP0452796
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-[(4-fluorophenyl)methoxy]phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C29H33FN8O5
|
2
|
| 1 |
EC50 = 432 nM
|
|
|
| 2 |
Ki = 235 nM
|
|
|
|
CP0398116
|
(2S,3S,4R,5R)-5-[6-amino-2-[3-(4-phenylpiperazin-1-yl)propylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H35N9O4
|
2
|
| 1 |
EC50 = 438 nM
|
|
|
| 2 |
Ki = 237 nM
|
|
|
|
CP0450331
|
9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C24H34N6O3
|
2
|
| 1 |
EC50 = 460 nM
|
|
|
| 2 |
Ki = 559 nM
|
|
|
|
CP0853683
|
(2R,3R,4S,5R)-2-(6-Amino-2-((E)-2-(4-chlorobenzylidene)hydrazinyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C17H18ClN7O4
|
1
|
| 1 |
EC50 = 493 nM
|
|
|
|
CP0894506
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-ethylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H25N5O3S
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0850123
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-methylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H23N5O3S
|
1
|
| 1 |
EC50 = 700 nM
|
|
|
|
CP0001102
|
(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C10H13N5O4
|
2
|
| 1 |
EC50 = 700 nM
|
|
|
| 2 |
Ki = 700 nM
|
|
|
|
CP0436336
|
(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C49H58N8O6
|
1
|
| 1 |
EC50 = 712 nM
|
|
|
|
CP0918920
|
2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H27N5O3S
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
|
CP0452790
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-(4-benzylpiperazin-1-yl)ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H35N9O4
|
2
|
| 1 |
EC50 = 842 nM
|
|
|
| 2 |
Ki = 659 nM
|
|
|
|
CP0720635
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C15H23N7O4
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0853682
|
(2R,3R,4S,5R)-2-(6-Amino-2-((E)-2-(4-methoxybenzylidene)hydrazinyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C18H21N7O5
|
1
|
| 1 |
EC50 = 1360 nM
|
|
|
|
CP0868084
|
(2S,3R,4S,5R,E)-6-(2-(6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-2-yl)hydrazono)hexane-1,2,3,4,5-pentaol
Show/Hide
|
C16H25N7O9
|
1
|
| 1 |
EC50 = 1440 nM
|
|
|
|
CP0888587
|
(2R,3R,4S,5R)-2-(6-Amino-2-((E)-2-(3,4-dichlorobenzylidene)hydrazinyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
|
C17H17Cl2N7O4
|
1
|
| 1 |
EC50 = 1660 nM
|
|
|
|
CP0397897
|
(2R,3S,4R,5R)-2-(2-ethyltetrazol-5-yl)-5-[6-(methylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C13H17N9O3
|
2
|
| 1 |
EC50 = 1710 nM
|
|
|
| 2 |
Ki = 778 nM
|
|
|
|
CP0398117
|
(2S,3S,4R,5R)-5-[6-amino-2-[2-[4-(2-phenylethyl)piperazin-1-yl]ethylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C26H37N9O4
|
2
|
| 1 |
EC50 = 1763 nM
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| 2 |
Ki = 967 nM
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CP0424294
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(2S,3S,4R,5R)-5-[2-[2-[4-[(3,5-ditert-butyl-4-hydroxybenzoyl)amino]phenyl]ethylamino]-6-(2,2-diphenylethylamino)purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
|
C48H56N8O6
|
1
|
| 1 |
EC50 = 2242 nM
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CP0854012
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2-(6-Amino-2-hex-1-ynyl-purin-9-yl)-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C19H27N5O3S
|
1
|
| 1 |
EC50 = 3600 nM
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CP0858897
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2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-methylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C16H25N7O3S
|
1
|
| 1 |
EC50 = 5000 nM
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CP0853973
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2-(6-Amino-2-iodo-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C10H12IN5O4
|
1
|
| 1 |
EC50 = 5400 nM
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CP0847369
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2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-ethylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C17H27N7O3S
|
1
|
| 1 |
EC50 = 7500 nM
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CP0374418
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4-N-(3-benzyl-5-phenyltriazolo[4,5-d]pyrimidin-7-yl)benzene-1,4-diamine
Show/Hide
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C23H19N7
|
3
|
| 1 |
EC50 = 9740 nM
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|
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| 2 |
Ki = 280 nM
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| 3 |
Ki = 1300 nM
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CP0056597
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1-[4-(3-Benzyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]-pyrimidin-7-ylamino)-phenyl]-3-(4-fluorophenyl)-urea
Show/Hide
|
C30H23FN8O
|
2
|
| 1 |
EC50 = 9950 nM
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| 2 |
EC50 = 16000 nM
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CP0054098
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2-isopropyl-4-(thiazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
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C12H11N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0082502
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4-(furan-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C10H7N3OS
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0082516
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2-methoxy-4-thiophen-2-ylthieno[3,2-d]pyrimidine
Show/Hide
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C11H8N2OS2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0082517
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N,N-dimethyl-4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C11H10N4S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0082518
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[(2S)-1-[4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-yl]pyrrolidin-2-yl]methanol
Show/Hide
|
C14H14N4OS2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0118626
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N,N-dimethyl-4-pyridin-2-ylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C13H12N4S
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
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CP0118627
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2-ethyl-4-(triazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
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C10H9N5S
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0118628
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2-[(4-thiophen-2-ylthieno[3,2-d]pyrimidin-2-yl)amino]ethanol
Show/Hide
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C12H11N3OS2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0118629
|
N,N-dimethyl-4-thiophen-2-ylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C12H11N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0118630
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N-ethyl-4-thiophen-2-ylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C12H11N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0118631
|
2-cyclopropyl-4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C12H9N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0136452
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2-ethyl-4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C11H9N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0153737
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2-chloro-4-thiophen-2-ylthieno[3,2-d]pyrimidine
Show/Hide
|
C10H5ClN2S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0156871
|
4-(furan-2-yl)-N,N-dimethylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C12H11N3OS
|
1
|
| 1 |
EC50 > 10000 nM
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CP0160053
|
2-[[4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-yl]amino]ethanol
Show/Hide
|
C11H10N4OS2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0160054
|
N,N-dimethyl-4-(1-methylimidazol-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H13N5S
|
1
|
| 1 |
EC50 > 10000 nM
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CP0160055
|
N,N-dimethyl-4-(5-methyl-1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H12N4S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0160056
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N,N-dimethyl-4-(4-methyl-1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H12N4S2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0160057
|
2-tert-butyl-4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C13H13N3S2
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1
|
| 1 |
EC50 > 10000 nM
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CP0160060
|
N-ethyl-4-(furan-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H11N3OS
|
1
|
| 1 |
EC50 > 10000 nM
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CP0160062
|
2-ethyl-4-(1H-imidazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C11H10N4S
|
1
|
| 1 |
EC50 > 10000 nM
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CP0170826
|
[(2R)-1-[4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-yl]pyrrolidin-2-yl]methanol
Show/Hide
|
C14H14N4OS2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0170827
|
4-(1H-imidazol-2-yl)-N,N-dimethylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C11H11N5S
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
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CP0170828
|
N,N-dimethyl-4-pyrazin-2-ylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H11N5S
|
1
|
| 1 |
EC50 > 10000 nM
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|
|
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CP0170829
|
2-[[4-(furan-2-yl)thieno[3,2-d]pyrimidin-2-yl]amino]ethanol
Show/Hide
|
C12H11N3O2S
|
1
|
| 1 |
EC50 > 10000 nM
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CP0170830
|
4-(1-benzothiophen-2-yl)-N,N-dimethylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C16H13N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0170832
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2-ethyl-4-(4-methyl-1,3-thiazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C12H11N3S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0202504
|
N,N-dimethyl-4-(5-methylpyridin-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C14H14N4S
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0241098
|
2-ethyl-4-(furan-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C12H10N2OS
|
1
|
| 1 |
EC50 > 10000 nM
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CP0255162
|
2-ethyl-4-(furan-3-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C12H10N2OS
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0255163
|
2-chloro-4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C9H4ClN3S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0255164
|
4-(4,5-dimethyl-1,3-thiazol-2-yl)-N,N-dimethylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C13H14N4S2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0255165
|
4-(1,3-thiazol-2-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C9H6N4S2
|
1
|
| 1 |
EC50 > 10000 nM
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CP0255166
|
4-(furan-3-yl)-N,N-dimethylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C12H11N3OS
|
1
|
| 1 |
EC50 > 10000 nM
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CP0255167
|
2-ethyl-4-pyridin-2-ylthieno[3,2-d]pyrimidine
Show/Hide
|
C13H11N3S
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0315506
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N,N-dimethyl-4-(1H-pyrazol-4-yl)thieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C11H11N5S
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0315507
|
2-ethyl-4-(6-methylpyridin-2-yl)thieno[3,2-d]pyrimidine
Show/Hide
|
C14H13N3S
|
1
|
| 1 |
EC50 > 10000 nM
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CP0318202
|
4-(furan-2-yl)-N-methylthieno[3,2-d]pyrimidin-2-amine
Show/Hide
|
C11H9N3OS
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0345233
|
2-ethyl-4-thiophen-2-ylthieno[3,2-d]pyrimidine
Show/Hide
|
C12H10N2S2
|
1
|
| 1 |
EC50 > 10000 nM
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|
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CP0399649
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-(2-methoxyethoxy)phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C25H34N8O6
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
Ki = 682 nM
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CP0399652
|
(2S,3S,4R,5R)-5-[6-amino-2-(4-phenylpiperazin-1-yl)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C22H28N8O4
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2
|
| 1 |
EC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0399654
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(2S,3S,4R,5R)-5-[6-amino-2-[4-(4-methoxyphenyl)piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C23H30N8O5
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2
|
| 1 |
EC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0399789
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-(4-fluorophenyl)piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C22H27FN8O4
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0452794
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-(4-phenylmethoxyphenyl)piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C29H34N8O5
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 745 nM
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CP0461003
|
(2S,3S,4R,5R)-5-[6-amino-2-[4-[4-(pyridin-4-ylmethoxy)phenyl]piperazin-1-yl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
|
C28H33N9O5
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
Ki > 10000 nM
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CP0847469
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-isopropylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H29N7O3S
|
1
|
| 1 |
EC50 = 10400 nM
|
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CP0916473
|
2-{6-Amino-2-[N'-(3-methyl-butylidene)-hydrazino]-purin-9-yl}-5-propylsulfanylmethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C18H29N7O3S
|
1
|
| 1 |
EC50 = 12900 nM
|
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CP0909022
|
2-(Furan-2-yl)-N5-(pyridin-3-yl-methyl)[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H12N6OS
|
2
|
| 1 |
IC50 = 0.011 nM
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|
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| 2 |
IC50 = 0.059 nM
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CP0476932
|
2-(furan-2-yl)-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5OS2
|
1
|
| 1 |
IC50 = 0.036 nM
|
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CP0389060
|
2-(furan-2-yl)-5-N-(furan-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5O2S
|
1
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| 1 |
IC50 = 0.04 nM
|
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CP0389062
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2-(furan-2-yl)-5-N-(2-thiophen-2-ylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H13N5OS2
|
1
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| 1 |
IC50 = 0.045 nM
|
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CP0415421
|
2-(furan-2-yl)-5-N-[(2-methoxyphenyl)methyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H15N5O2S
|
1
|
| 1 |
IC50 = 0.051 nM
|
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CP0415414
|
2-(furan-2-yl)-5-N-[(3-methoxyphenyl)methyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H15N5O2S
|
1
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| 1 |
IC50 = 0.095 nM
|
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CP0864769
|
2-(Furan-2-yl)-N5-[2-(pyridin-3-yl)ethyl][1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C16H14N6OS
|
3
|
| 1 |
IC50 = 0.29 nM
|
|
|
| 2 |
IC50 = 0.35 nM
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|
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| 3 |
Ki = 0.24 nM
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CP0408077
|
2-(furan-2-yl)-5-N-(thiophen-3-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5OS2
|
3
|
| 1 |
IC50 = 0.36 nM
|
|
|
| 2 |
IC50 = 0.41 nM
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|
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| 3 |
Ki = 0.25 nM
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CP0053494
|
4-(2-{[5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]amino}ethyl)phenol
Show/Hide
|
C16H15N7O2
|
9
|
| 1 |
IC50 = 0.678 nM
|
|
|
| 2 |
IC50 = 0.83 nM
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|
|
| 3 |
IC50 = 1.24 nM
|
|
|
| 4 |
IC50 = 1.45 nM
|
|
|
| 5 |
Ki = 0.87 nM
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|
|
| 6 |
Ki = 0.91 nM
|
|
|
| 7 |
Ki = 0.93 nM
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|
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| 8 |
Ki = 1.2 nM
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|
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| 9 |
Ki = 1.3 nM
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CP0411541
|
2-(furan-2-yl)-5-N-(pyridin-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H12N6OS
|
3
|
| 1 |
IC50 = 0.68 nM
|
|
|
| 2 |
IC50 = 1.3 nM
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|
|
| 3 |
Ki = 0.42 nM
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CP0411540
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2-(furan-2-yl)-5-N-[2-(furan-2-yl)ethyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H13N5O2S
|
3
|
| 1 |
IC50 = 2.93 nM
|
|
|
| 2 |
IC50 = 4.26 nM
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|
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| 3 |
Ki = 2.15 nM
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CP0408078
|
5-N-[(2-methoxyphenyl)methyl]-2-thiophen-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H15N5OS2
|
3
|
| 1 |
IC50 = 3.36 nM
|
|
|
| 2 |
IC50 = 4.41 nM
|
|
|
| 3 |
Ki = 2.24 nM
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CP0414588
|
2-[(2-methoxyphenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C18H17N5O2
|
2
|
| 1 |
IC50 = 4.35 nM
|
|
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| 2 |
Ki = 3.62 nM
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CP0389698
|
5-N-[(2-methoxyphenyl)methyl]-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C19H17N5OS
|
3
|
| 1 |
IC50 = 5.34 nM
|
|
|
| 2 |
IC50 = 7.63 nM
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|
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| 3 |
Ki = 4.72 nM
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CP0399160
|
5-(furan-2-yl)-2-[(2-methoxyphenyl)methyl]pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C17H15N5O2
|
2
|
| 1 |
IC50 = 6.21 nM
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|
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| 2 |
Ki = 5.37 nM
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CP0379859
|
2-[(3-methoxyphenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C18H17N5O2
|
2
|
| 1 |
IC50 = 6.42 nM
|
|
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| 2 |
Ki = 5.26 nM
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CP0127357
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methylpiperazin-1-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide
Show/Hide
|
C21H26N8O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0389063
|
2-(furan-2-yl)-5-N-(pyrazin-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N7OS
|
3
|
| 1 |
IC50 = 8.27 nM
|
|
|
| 2 |
IC50 = 11.3 nM
|
|
|
| 3 |
Ki = 5.14 nM
|
|
|
|
CP0382854
|
2-benzyl-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C17H15N5O
|
2
|
| 1 |
IC50 = 10.91 nM
|
|
|
| 2 |
Ki = 9.23 nM
|
|
|
|
CP0310128
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(morpholin-4-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0389061
|
2-thiophen-2-yl-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C14H11N5S3
|
3
|
| 1 |
IC50 = 13.2 nM
|
|
|
| 2 |
IC50 = 17.6 nM
|
|
|
| 3 |
Ki = 10.1 nM
|
|
|
|
CP0864770
|
2-(Furan-2-yl)-N5-(pyridin-4-yl-methyl)[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C15H12N6OS
|
3
|
| 1 |
IC50 = 15.3 nM
|
|
|
| 2 |
IC50 = 18.7 nM
|
|
|
| 3 |
Ki = 12 nM
|
|
|
|
CP0446615
|
2-(furan-2-yl)-5-N-(2-phenylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H15N5OS
|
3
|
| 1 |
IC50 = 16 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
| 3 |
Ki = 30 nM
|
|
|
|
CP0373930
|
N-[6-(3,5-dimethoxyphenyl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidin-4-yl]acetamide
Show/Hide
|
C19H21N5O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0399741
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(3-methoxyazetidin-1-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0415419
|
5-N-benzyl-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C16H13N5OS
|
3
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 29 nM
|
|
|
| 3 |
Ki = 22 nM
|
|
|
|
CP0451426
|
4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]phenol
Show/Hide
|
C17H15N5O2S
|
3
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
IC50 = 25 nM
|
|
|
| 3 |
Ki = 18 nM
|
|
|
|
CP0373931
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-hydroxypiperidin-1-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide
Show/Hide
|
C21H25N7O2
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0415415
|
3-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]phenol
Show/Hide
|
C16H13N5O2S
|
3
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
IC50 = 27 nM
|
|
|
| 3 |
Ki = 20 nM
|
|
|
|
CP0383019
|
2-amino-4-(furan-2-yl)-6-[[3-(hydroxymethyl)phenyl]methylsulfanyl]pyridine-3,5-dicarbonitrile
Show/Hide
|
C19H14N4O2S
|
2
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
Ki = 31 nM
|
|
|
|
CP0375126
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypyridin-3-yl)pyrimidin-4-yl]propanamide
Show/Hide
|
C18H20N6O2
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0415417
|
2-(furan-2-yl)-5-N-[2-(4-methoxyphenyl)ethyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C18H17N5O2S
|
3
|
| 1 |
IC50 = 31 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
| 3 |
Ki = 32 nM
|
|
|
|
CP0497739
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(2-fluoro-3-methoxyphenyl)pyrimidin-4-yl]acetamide
Show/Hide
|
C18H18FN5O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0389696
|
2-phenyl-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C16H13N5S2
|
3
|
| 1 |
IC50 = 36 nM
|
|
|
| 2 |
IC50 = 43 nM
|
|
|
| 3 |
Ki = 28 nM
|
|
|
|
CP0389697
|
5-N-[(3-methoxyphenyl)methyl]-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C19H17N5OS
|
3
|
| 1 |
IC50 = 48 nM
|
|
|
| 2 |
IC50 = 66 nM
|
|
|
| 3 |
Ki = 42 nM
|
|
|
|
CP0467978
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypyridin-3-yl)pyrimidin-4-yl]-2-(morpholin-4-yl)acetamide
Show/Hide
|
C21H25N7O3
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0272424
|
N-[2-(3,5-dimethylpyrazol-1-yl)-6-(5-methoxypyridin-3-yl)pyrimidin-4-yl]acetamide
Show/Hide
|
C17H18N6O2
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0439989
|
3-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]benzamide
Show/Hide
|
C19H13N5O2S
|
2
|
| 1 |
IC50 = 58 nM
|
|
|
| 2 |
Ki = 67 nM
|
|
|
|
CP0373932
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-hydroxypyridin-3-yl)pyrimidin-4-yl]acetamide
Show/Hide
|
C16H16N6O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0439413
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-{6-[(2-methoxyethyl)(methyl)amino]pyridin-2-yl}pyrimidin-4-yl]acetamide
Show/Hide
|
C20H25N7O2
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
|
CP0446803
|
2-methyl-5-N-(2-thiophen-2-ylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C12H13N5S2
|
3
|
| 1 |
IC50 = 83 nM
|
|
|
| 2 |
IC50 = 102 nM
|
|
|
| 3 |
Ki = 61 nM
|
|
|
|
CP0383006
|
2-amino-4-(furan-2-yl)-6-(pyridin-3-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
|
C17H11N5OS
|
2
|
| 1 |
IC50 = 83 nM
|
|
|
| 2 |
Ki = 24 nM
|
|
|
|
CP0432539
|
8-amino-6-(4-ethoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H17N5O2
|
2
|
| 1 |
IC50 = 98 nM
|
|
|
| 2 |
Ki = 2.9 nM
|
|
|
|
CP0482762
|
N-[2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]ethyl]-5-(dithiolan-3-yl)pentanamide
Show/Hide
|
C27H30N6O3S2
|
2
|
| 1 |
IC50 = 116 nM
|
|
|
| 2 |
Ki = 2.4 nM
|
|
|
|
CP0415416
|
2-(furan-2-yl)-5-N-[(4-methoxyphenyl)methyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H15N5O2S
|
3
|
| 1 |
IC50 = 123 nM
|
|
|
| 2 |
IC50 = 187 nM
|
|
|
| 3 |
Ki = 171 nM
|
|
|
|
CP0058033
|
1,3-dipropyl-8-cyclopentylxanthine
Show/Hide
|
C16H24N4O2
|
7
|
| 1 |
IC50 = 132 nM
|
|
|
| 2 |
Ki = 97 nM
|
|
|
| 3 |
Ki = 129 nM
|
|
|
| 4 |
Ki = 130 nM
|
|
|
| 5 |
Ki = 260 nM
|
|
|
| 6 |
Ki = 260.3 nM
|
|
|
| 7 |
Ki = 337 nM
|
|
|
|
CP0466764
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(dimethylamino)pyridin-2-yl]pyrimidin-4-yl]acetamide
Show/Hide
|
C18H21N7O
|
1
|
| 1 |
IC50 = 156 nM
|
|
|
|
CP0479029
|
2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]acetonitrile
Show/Hide
|
C19H14N6O2
|
2
|
| 1 |
IC50 = 157 nM
|
|
|
| 2 |
Ki = 8.2 nM
|
|
|
|
CP0537189
|
5-(furan-2-yl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C15H10N4OS
|
2
|
| 1 |
IC50 = 163 nM
|
|
|
| 2 |
Ki = 1.7 nM
|
|
|
|
CP0462579
|
methyl N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypyridin-3-yl)pyrimidin-4-yl]carbamate
Show/Hide
|
C17H18N6O3
|
1
|
| 1 |
IC50 = 167 nM
|
|
|
|
CP0393992
|
8-amino-6-(3-tert-butyl-4-hydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C21H21N5O2
|
2
|
| 1 |
IC50 = 179 nM
|
|
|
| 2 |
Ki = 8.5 nM
|
|
|
|
CP0448681
|
8-amino-6-(4-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C18H15N5O2
|
2
|
| 1 |
IC50 = 180 nM
|
|
|
| 2 |
Ki = 7.2 nM
|
|
|
|
CP0462580
|
ethyl N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-(5-methoxypyridin-3-yl)pyrimidin-4-yl]carbamate
Show/Hide
|
C18H20N6O3
|
1
|
| 1 |
IC50 = 196 nM
|
|
|
|
CP0373934
|
N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[5-(morpholin-4-yl)pyridin-3-yl]pyrimidin-4-yl]acetamide
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 = 213 nM
|
|
|
|
CP0445899
|
N-[3-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)anilino]-3-oxopropyl]-3,5-ditert-butyl-4-hydroxybenzamide
Show/Hide
|
C35H39N7O4
|
2
|
| 1 |
IC50 = 263 nM
|
|
|
| 2 |
Ki = 54.5 nM
|
|
|
|
CP0445903
|
N-[3-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)anilino]-3-oxopropyl]-5-(dithiolan-3-yl)pentanamide
Show/Hide
|
C28H31N7O3S2
|
2
|
| 1 |
IC50 = 296 nM
|
|
|
| 2 |
Ki = 36.4 nM
|
|
|
|
CP0427864
|
2,5-bis(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C13H8N4O2S
|
2
|
| 1 |
IC50 = 301 nM
|
|
|
| 2 |
Ki = 3.4 nM
|
|
|
|
CP0477262
|
methyl 3-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]benzoate
Show/Hide
|
C20H14N4O3S
|
2
|
| 1 |
IC50 = 313 nM
|
|
|
| 2 |
Ki = 68 nM
|
|
|
|
CP0375235
|
2-phenyl-5-(3-phenylpropyl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C20H19N5
|
2
|
| 1 |
IC50 = 423 nM
|
|
|
| 2 |
Ki = 55 nM
|
|
|
|
CP0455835
|
3-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)phenol
Show/Hide
|
C17H12N4OS
|
2
|
| 1 |
IC50 = 627 nM
|
|
|
| 2 |
Ki = 5 nM
|
|
|
|
CP0517726
|
3-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]phenol
Show/Hide
|
C15H10N4O2S
|
2
|
| 1 |
IC50 = 764 nM
|
|
|
| 2 |
Ki = 1.64 nM
|
|
|
|
CP0415983
|
3-ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
Show/Hide
|
C18H22F3N3O4S
|
1
|
| 1 |
IC50 = 820 nM
|
|
|
|
CP0372710
|
[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxythiolan-2-yl]-(4-methylpiperazin-1-yl)methanone
Show/Hide
|
C22H25ClIN7O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0372711
|
(2S,3S,4R,5R)-5-[2-chloro-6-(cyclobutylamino)purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C16H21ClN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0372712
|
(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-N-ethyl-3,4-dihydroxy-N-phenylthiolane-2-carboxamide
Show/Hide
|
C25H24ClIN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0372713
|
(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyl-N-propylthiolane-2-carboxamide
Show/Hide
|
C21H24ClIN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0372714
|
[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxythiolan-2-yl]-(4-hydroxypiperidin-1-yl)methanone
Show/Hide
|
C22H24ClIN6O4S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0382105
|
[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxythiolan-2-yl]-pyrrolidin-1-ylmethanone
Show/Hide
|
C21H22ClIN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0384292
|
(2S,3S,4R,5R)-5-[6-[(3-bromophenyl)methylamino]-2-chloropurin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C19H20BrClN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0384294
|
(2S,3S,4R,5R)-5-[2-chloro-6-(cyclopropylmethylamino)purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C16H21ClN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0384298
|
(2S,3S,4R,5R)-5-[2-chloro-6-[(3-chlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C19H20Cl2N6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0384299
|
(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-(2-hydroxyethyl)-N-methylthiolane-2-carboxamide
Show/Hide
|
C20H22ClIN6O4S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0384300
|
(2S,3S,4R,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C17H23ClN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0405185
|
(2S,3S,4R,5R)-5-[2-chloro-6-(dimethylamino)purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C14H19ClN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0405186
|
(2S,3S,4R,5R)-5-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C19H20ClFN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0405187
|
(2S,3S,4R,5R)-5-[2-chloro-6-(2-methoxyethylamino)purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C15H21ClN6O4S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0431802
|
[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxythiolan-2-yl]-piperidin-1-ylmethanone
Show/Hide
|
C22H24ClIN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0444300
|
azetidin-1-yl-[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxythiolan-2-yl]methanone
Show/Hide
|
C20H20ClIN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0444339
|
[(2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methylamino]purin-9-yl]-3,4-dihydroxythiolan-2-yl]-thiomorpholin-4-ylmethanone
Show/Hide
|
C21H22ClIN6O3S2
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0501252
|
(2S,3S,4R,5R)-5-[2-chloro-6-(cyclopropylamino)purin-9-yl]-3,4-dihydroxy-N,N-dimethylthiolane-2-carboxamide
Show/Hide
|
C15H19ClN6O3S
|
1
|
| 1 |
IC50 >= 10000 nM
|
|
|
|
CP0472500
|
[(2R,3S,4R,5R)-5-[6-chloro-4-(cyclopentylamino)pyrazolo[3,4-d]pyrimidin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxymethylphosphonic acid
Show/Hide
|
C16H23ClN5O7P
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0109685
|
N-(4-cyanophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
Show/Hide
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C23H19N5O4
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1
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| 1 |
Kd = 50.12 nM
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CP0194534
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2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-fluorophenyl)acetamide
Show/Hide
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C22H19FN4O4
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1
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| 1 |
Kd = 57.54 nM
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CP0173340
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2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-phenylacetamide
Show/Hide
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C22H20N4O4
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1
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| 1 |
Kd = 630.96 nM
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CP0077961
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N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
Show/Hide
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C22H19BrN4O4
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1
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| 1 |
Kd = 1023.29 nM
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CP0058627
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N-(4-bromophenyl)-2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-3-methoxyphenoxy]acetamide
Show/Hide
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C23H21BrN4O5
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1
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| 1 |
Kd = 1258.93 nM
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CP0099553
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2-[4-(1-methyl-2,4-dioxo-3-propyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]-N-(4-phenylphenyl)acetamide
Show/Hide
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C30H28N4O4
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1
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| 1 |
Kd = 3162.28 nM
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CP0395280
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8-[4-(3-imidazol-1-ylpropoxy)phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C19H20N6O3
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1
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| 1 |
Ki = 0.042 nM
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CP0395278
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8-[4-(3-chloropropoxy)phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C16H17ClN4O3
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1
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| 1 |
Ki = 0.045 nM
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CP0069173
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2-Furan-2-yl-7-[3-(4-methoxy-phenyl)-propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C20H19N7O2
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1
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| 1 |
Ki = 0.048 nM
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CP0380983
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8-(4-cyclopentyloxyphenyl)-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C18H20N4O3
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1
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| 1 |
Ki = 0.072 nM
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CP0496241
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2,2'-(4-(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)phenylazanediyl)diethanol
Show/Hide
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C22H24N8O3
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1
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| 1 |
Ki = 0.12 nM
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CP0431958
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8-[4-[3-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]propoxy]phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C27H31ClN6O3
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1
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| 1 |
Ki = 0.12 nM
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CP0377048
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7-(3-(4-(aminomethyl)phenyl)propyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H20N8O
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1
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| 1 |
Ki = 0.13 nM
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CP0116393
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2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 0.16 nM
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CP0436901
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8-amino-6-(4-methoxy-3,5-dimethylphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H19N5O2
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1
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| 1 |
Ki = 0.17 nM
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CP0460044
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(5-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzo[d][1,3]dioxole-2,2-diyl)dimethanol
Show/Hide
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C22H21N7O5
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1
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| 1 |
Ki = 0.19 nM
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CP0458924
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1,3-dimethyl-8-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7H-purine-2,6-dione
Show/Hide
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C19H23N5O3
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1
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| 1 |
Ki = 0.2 nM
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CP0383172
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7-(3-(4-aminophenyl)propyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C19H18N8O
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1
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| 1 |
Ki = 0.22 nM
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CP0380872
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8-[4-[2-(diethylamino)ethoxy]phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C19H25N5O3
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1
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| 1 |
Ki = 0.25 nM
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CP0380982
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1,3-dimethyl-8-[4-(2-piperidin-4-ylethoxy)phenyl]-7H-purine-2,6-dione
Show/Hide
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C20H25N5O3
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1
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| 1 |
Ki = 0.29 nM
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CP0395279
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1,3-dimethyl-8-[4-(2-morpholin-4-ylethoxy)phenyl]-7H-purine-2,6-dione
Show/Hide
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C19H23N5O4
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1
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| 1 |
Ki = 0.31 nM
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CP0293183
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2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C18H15N7O
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1
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| 1 |
Ki = 0.34 nM
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CP0044275
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9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine
Show/Hide
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C13H8ClN5O
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8
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| 1 |
Ki = 0.35 nM
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| 2 |
Ki = 0.41 nM
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| 3 |
Ki = 0.43 nM
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| 4 |
Ki = 0.52 nM
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| 5 |
Ki = 0.67 nM
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| 6 |
Ki = 0.84 nM
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| 7 |
Ki = 0.91 nM
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| 8 |
Ki = 1 nM
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CP0431957
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8-[4-[2-(dimethylamino)ethoxy]phenyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C17H21N5O3
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1
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| 1 |
Ki = 0.4 nM
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CP0376685
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ethyl 2-[4-[3-[7-amino-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-10-yl]propyl]phenoxy]acetate
Show/Hide
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C23H23N7O4
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1
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| 1 |
Ki = 0.43 nM
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CP0418184
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4-(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)-N,N-bis(2-chloroethyl)benzenesulfonamide
Show/Hide
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C22H22Cl2N8O3S
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1
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| 1 |
Ki = 0.59 nM
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CP0387019
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3-amino-N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]propanamide
Show/Hide
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C20H19N7O2
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1
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| 1 |
Ki = 0.59 nM
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CP0255917
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2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C15H17N7O
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1
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| 1 |
Ki = 0.78 nM
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CP0045163
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2-(furan-2-yl)-8-(3-methylbut-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C15H15N7O
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1
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| 1 |
Ki = 0.8 nM
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CP0294067
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4-(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)-N,N-bis(2-hydroxyethyl)benzenesulfonamide
Show/Hide
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C22H24N8O5S
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1
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| 1 |
Ki = 0.8 nM
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CP0446617
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5-N-[(3-fluorophenyl)methyl]-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C16H12FN5OS
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1
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| 1 |
Ki = 0.82 nM
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CP0035607
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2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]-piperazin-1-yl}-ethyl)-2,7-dihydro-3H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C25H29N9O3
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2
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| 1 |
Ki = 0.88 nM
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| 2 |
Ki = 0.884 nM
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CP0469720
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2-(furan-2-yl)-7-(3-(4-nitrophenyl)propyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C19H16N8O3
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1
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| 1 |
Ki = 1 nM
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CP0054097
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2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C18H15N7O
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1
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| 1 |
Ki = 1.1 nM
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CP0447324
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2,2'-(4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenylazanediyl)diethanol
Show/Hide
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C23H26N8O3
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1
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| 1 |
Ki = 1.1 nM
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CP0468152
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5-N-benzyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C15H13N7O
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1
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| 1 |
Ki = 1.11 nM
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CP0146462
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2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C12H11N7OS
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1
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| 1 |
Ki = 1.2 nM
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CP0393327
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2-(furan-2-yl)-7-(3-phenylpropyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 1.2 nM
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CP0404386
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4-(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)benzenesulfonamide
Show/Hide
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C18H16N8O3S
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1
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| 1 |
Ki = 1.31 nM
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CP0385357
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1-[5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
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C22H18N8O2
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1
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| 1 |
Ki = 1.44 nM
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CP0403353
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4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)phenol
Show/Hide
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C19H17N7O2
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1
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| 1 |
Ki = 1.5 nM
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CP0045160
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8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C14H15N7O
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1
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| 1 |
Ki = 1.6 nM
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CP0484510
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US9018371, 2
Show/Hide
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C16H15Cl2N5O2S
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1
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| 1 |
Ki = 1.66 nM
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CP0407836
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(2R,3R,4S,5R)-2-[6-amino-2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C19H19N5O5
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1
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| 1 |
Ki = 1.8 nM
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CP0479028
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N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]prop-2-enamide
Show/Hide
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C20H16N6O2
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1
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| 1 |
Ki = 1.8 nM
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CP0427865
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2-(furan-2-yl)-5-(3-methoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
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C16H12N4O2S
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1
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| 1 |
Ki = 1.9 nM
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CP0258378
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8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C12H11N7O
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1
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| 1 |
Ki = 1.95 nM
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CP0409677
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(2S,3S,4R,5R)-5-(6-amino-2-((S)-3-hydroxy-3-phenylprop-1-ynyl)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
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C21H22N6O5
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1
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| 1 |
Ki = 2 nM
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CP0527116
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2-[4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]piperidin-1-yl]-N-(4-sulfamoylphenyl)acetamide
Show/Hide
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C23H26N8O4S2
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1
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| 1 |
Ki = 2.02 nM
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CP0496284
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2-(furan-2-yl)-8-methyl-9-(propylthio)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C14H15N7OS
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1
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| 1 |
Ki = 2.1 nM
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CP0517721
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[3-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]phenyl]methanol
Show/Hide
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C16H12N4O2S
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1
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| 1 |
Ki = 2.1 nM
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CP0445432
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4-amino-8-chloro-2-p-tolyl-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
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C16H12ClN5O
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1
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| 1 |
Ki = 2.3 nM
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CP0431166
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(2R,3R,4S,5R)-2-[6-amino-2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]purin-9-yl]-5-(1-ethyltetrazol-5-yl)oxolane-3,4-diol
Show/Hide
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C21H26N10O4
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1
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| 1 |
Ki = 2.3 nM
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CP0455823
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2-(furan-2-yl)-5-(5-methylfuran-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
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C14H10N4O2S
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1
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| 1 |
Ki = 2.36 nM
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CP0445898
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8-amino-6-(2,4-dimethoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 2.4 nM
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CP0436898
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8-amino-6-(4-hydroxy-3,5-dimethylphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C19H17N5O2
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1
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| 1 |
Ki = 2.5 nM
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CP0222480
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2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C13H13N7O
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1
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| 1 |
Ki = 2.51 nM
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CP0419179
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7-(3-(3,4-dimethoxyphenyl)propyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C21H21N7O3
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1
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| 1 |
Ki = 2.7 nM
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CP0278022
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2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C11H9N7O
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1
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| 1 |
Ki = 2.8 nM
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CP0491669
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2-(furan-2-yl)-5-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
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C15H10N4OS
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1
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| 1 |
Ki = 3 nM
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CP0393692
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(2S,3S,4R,5R)-5-[6-amino-2-(3-hydroxy-3-phenylprop-1-ynyl)purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C21H22N6O5
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1
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| 1 |
Ki = 3.1 nM
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CP0498105
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1-(2-Furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C20H18N8O3S
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1
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| 1 |
Ki = 3.1 nM
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CP0380867
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8-[[4-(3-imidazol-1-ylpropoxy)phenyl]methyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C20H22N6O3
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1
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| 1 |
Ki = 3.17 nM
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CP0405188
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7-(3-(benzo[d][1,3]dioxol-5-yl)propyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H17N7O3
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1
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| 1 |
Ki = 3.3 nM
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CP0380882
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ethyl 5-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C12H11N5O3
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1
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| 1 |
Ki = 3.32 nM
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CP0448650
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8-amino-6-(3-hydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
Ki = 3.5 nM
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CP0450753
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8-amino-2-phenyl-6-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H19N5O4
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1
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| 1 |
Ki = 3.5 nM
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CP0483580
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5-N-cyclohexyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C14H17N7O
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1
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| 1 |
Ki = 3.56 nM
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CP0183628
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(2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (2-amino-ethyl)-amide
Show/Hide
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C12H17N7O4
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7
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| 1 |
Ki = 3.6 nM
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| 2 |
Ki = 4.4 nM
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| 3 |
Ki = 41 nM
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| 4 |
Ki = 46.1 nM
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| 5 |
Ki = 57 nM
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| 6 |
Ki = 72 nM
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| 7 |
Ki = 121 nM
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CP0385422
|
11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
|
C11H9N7O
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0527896
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-morpholin-4-ylpropanamide
Show/Hide
|
C24H25N7O3
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0570676
|
US9018371, 10
Show/Hide
|
C10H12ClN5O2S
|
1
|
| 1 |
Ki = 3.69 nM
|
|
|
|
CP0353552
|
9-ethyl-8-(furan-2-yl)purin-6-amine
Show/Hide
|
C11H11N5O
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0422166
|
2-(furan-2-yl)-7-(4-(4-methylpiperazin-1-ylsulfonyl)phenethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
|
C23H25N9O3S
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0463046
|
4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H16N6O
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0514625
|
ethyl 4-[2-[7-amino-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-10-yl]ethyl]benzoate
Show/Hide
|
C21H19N7O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0544075
|
2-amino-4-phenyl-8-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 4.01 nM
|
|
|
|
CP0420752
|
2-Benzo[1,3]dioxol-5-yl-N-(2-furan-2-yl-8-methyl-9-methylsulfanyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-acetamide
Show/Hide
|
C21H17N7O4S
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0562150
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-pyrrolidin-1-ylpropanamide
Show/Hide
|
C24H25N7O2
|
1
|
| 1 |
Ki = 4.31 nM
|
|
|
|
CP0422849
|
4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzimidamide
Show/Hide
|
C20H19N9O
|
1
|
| 1 |
Ki = 4.4 nM
|
|
|
|
CP0422758
|
4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzoic acid
Show/Hide
|
C20H17N7O3
|
1
|
| 1 |
Ki = 4.63 nM
|
|
|
|
CP0455003
|
4-amino-8-chloro-2-phenyl-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
|
C15H10ClN5O
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0383255
|
N-[4-[2-[7-amino-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-10-yl]ethyl]phenyl]acetamide
Show/Hide
|
C20H18N8O2
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0456031
|
ethyl 2-(furan-2-yl)-5-(phenylcarbamoylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C19H16N6O4
|
1
|
| 1 |
Ki = 4.82 nM
|
|
|
|
CP0542599
|
4-phenyl-8-(3-piperidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 4.85 nM
|
|
|
|
CP0490059
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-5-(dithiolan-3-yl)pentanamide
Show/Hide
|
C25H26N6O2S2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0448649
|
8-amino-2-phenyl-6-(3-prop-2-ynoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C20H15N5O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0567607
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-piperidin-1-ylpropanamide
Show/Hide
|
C25H27N7O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0387016
|
8-amino-6-(3,4-dihydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C17H13N5O3
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0076359
|
3-(3-Hydroxy-propyl)-8-[2-(3-methoxy-phenyl)-vinyl]-7-methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione(MSX-2)
Show/Hide
|
C21H22N4O4
|
1
|
| 1 |
Ki = 5.38 nM
|
|
|
|
CP0468155
|
N-[5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
|
C23H19N7O2
|
1
|
| 1 |
Ki = 5.39 nM
|
|
|
|
CP0469719
|
(S)-ethyl 5-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzo[d][1,3]dioxole-2-carboxylate
Show/Hide
|
C23H21N7O5
|
1
|
| 1 |
Ki = 5.48 nM
|
|
|
|
CP0436904
|
8-amino-6-(3,4-dimethoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
Ki = 5.7 nM
|
|
|
|
CP0340022
|
4-[4-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperazin-1-yl]benzenesulfonamide
Show/Hide
|
C19H19N7O3S2
|
1
|
| 1 |
Ki = 5.73 nM
|
|
|
|
CP0396834
|
2-(furan-2-yl)-N-methyl-5-(phenylcarbamoylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C18H15N7O3
|
1
|
| 1 |
Ki = 5.76 nM
|
|
|
|
CP0383256
|
4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)-N'-hydroxybenzimidamide
Show/Hide
|
C20H19N9O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0477182
|
2-(furan-2-yl)-5-(methylamino)-N-(2-methyl-1-phenylpropan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C21H22N6O2
|
1
|
| 1 |
Ki = 6.12 nM
|
|
|
|
CP0407419
|
2-[(2-chlorophenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C17H14ClN5O
|
1
|
| 1 |
Ki = 6.21 nM
|
|
|
|
CP0562422
|
2-amino-4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C24H24N4O2
|
1
|
| 1 |
Ki = 6.24 nM
|
|
|
|
CP0054093
|
tert-butyl 1-[(2R,3S)-3-[[(2S)-4-amino-4-oxo-2-(phenylmethoxycarbonylamino)butanoyl]amino]-2-hydroxy-4-phenylbutyl]pyrrolidine-2-carboxylate
Show/Hide
|
C31H42N4O7
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0377319
|
(2R,3R,4S,5S)-4-Amino-5-hydroxymethyl-2-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-3-ol
Show/Hide
|
C17H19IN6O3
|
7
|
| 1 |
Ki = 6.4 nM
|
|
|
| 2 |
Ki = 18 nM
|
|
|
| 3 |
Ki = 57 nM
|
|
|
| 4 |
Ki = 64 nM
|
|
|
| 5 |
Ki = 67 nM
|
|
|
| 6 |
Ki = 87 nM
|
|
|
| 7 |
Ki = 88 nM
|
|
|
|
CP0427937
|
8-(4-(4-(4-chlorobenzyl)piperazin-1-ylsulfonyl)phenyl)-1-ethyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C24H25ClN6O4S
|
1
|
| 1 |
Ki = 6.49 nM
|
|
|
|
CP0378381
|
(2R,3R,4S,5S)-2-(6-(3-iodobenzylamino)-9H-purin-9-yl)-4-(aminomethyl)-5-(hydroxymethyl)-tetrahydrofuran-3-ol
Show/Hide
|
C18H21IN6O3
|
7
|
| 1 |
Ki = 6.5 nM
|
|
|
| 2 |
Ki = 56 nM
|
|
|
| 3 |
Ki = 58 nM
|
|
|
| 4 |
Ki = 59 nM
|
|
|
| 5 |
Ki = 64 nM
|
|
|
| 6 |
Ki = 67 nM
|
|
|
| 7 |
Ki = 79 nM
|
|
|
|
CP0853605
|
N2-benzyl-8-(furan-2-yl)-9-propyl-9H-purine-2,6-diamine
Show/Hide
|
C19H20N6O
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0465323
|
N-(4-phenyl-5-pyridin-4-yl-1,3-thiazol-2-yl)furan-2-carboxamide
Show/Hide
|
C19H13N3O2S
|
1
|
| 1 |
Ki = 6.65 nM
|
|
|
|
CP0455780
|
8-amino-6-(3-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C18H15N5O2
|
1
|
| 1 |
Ki = 6.8 nM
|
|
|
|
CP0458861
|
(2R,3R,4S,5R)-2-[6-amino-2-(3-hydroxy-3-phenylprop-1-ynyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C19H19N5O5
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0544077
|
4-phenyl-8-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 7.25 nM
|
|
|
|
CP0437653
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-[4-(2-hydroxyethyl)piperazin-1-yl]propanamide
Show/Hide
|
C26H30N8O3
|
1
|
| 1 |
Ki = 7.27 nM
|
|
|
|
CP0425345
|
US9018371, 1
Show/Hide
|
C16H15ClFN5O2S
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0432536
|
8-amino-2-phenyl-6-(4-propan-2-yloxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C20H19N5O2
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0387017
|
8-amino-6-(1,3-benzodioxol-5-yl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C18H13N5O3
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0473788
|
8-(furan-2-yl)-9-methylpurin-6-amine
Show/Hide
|
C10H9N5O
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0234114
|
2-amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C23H22N4O3
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0436060
|
3-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]benzonitrile
Show/Hide
|
C16H9N5OS
|
1
|
| 1 |
Ki = 7.7 nM
|
|
|
|
CP0517718
|
[4-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]phenyl]methanol
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
Ki = 7.7 nM
|
|
|
|
CP0401194
|
1-[5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
|
C21H22N8O2
|
1
|
| 1 |
Ki = 7.87 nM
|
|
|
|
CP0431956
|
8-[[4-[3-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)propoxy]phenyl]methyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
|
C24H31N5O5
|
1
|
| 1 |
Ki = 8.09 nM
|
|
|
|
CP0441294
|
11-(furan-2-yl)-4-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C11H9N7O
|
1
|
| 1 |
Ki = 8.1 nM
|
|
|
|
CP0471139
|
5-N-butyl-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C13H15N5OS
|
1
|
| 1 |
Ki = 8.21 nM
|
|
|
|
CP0541441
|
US9018371, 3
Show/Hide
|
C16H15BrClN5O2S
|
1
|
| 1 |
Ki = 8.99 nM
|
|
|
|
CP0428490
|
4-amino-2-(4-methoxy-phenyl)-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
|
C16H13N5O2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0395751
|
11-(furan-2-yl)-4-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C18H15N7O
|
1
|
| 1 |
Ki = 9.2 nM
|
|
|
|
CP0471400
|
(2R,3R,4S,5R)-2-(6-amino-2-phenethoxy-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C18H21N5O5
|
1
|
| 1 |
Ki = 9.3 nM
|
|
|
|
CP0437409
|
1-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C21H15ClN6O3
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0102758
|
1-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)-3-(3-chloro-phenyl)-urea
Show/Hide
|
C20H12Cl2N6O2
|
1
|
| 1 |
Ki = 9.5 nM
|
|
|
|
CP0401647
|
12-N-ethyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene-7,12-diamine
Show/Hide
|
C13H14N8O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0869371
|
N*9*-Ethyl-2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine-5,9-diamine hydrochloride
Show/Hide
|
C13H15ClN8O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0455781
|
8-amino-2,6-diphenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C17H13N5O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0458430
|
8-amino-2-phenyl-6-(4-prop-2-ynoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C20H15N5O2
|
1
|
| 1 |
Ki = 10.6 nM
|
|
|
|
CP0432011
|
(2R,3R,4S,5R)-2-(6-amino-2-(2-(thiophen-2-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C16H19N5O5S
|
1
|
| 1 |
Ki = 10.9 nM
|
|
|
|
CP0427814
|
11-(furan-2-yl)-4-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
|
C19H17N7O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0394638
|
1-phenylethyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C19H17N5O3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0552753
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-(4-methylpiperazin-1-yl)propanamide
Show/Hide
|
C25H28N8O2
|
1
|
| 1 |
Ki = 11.03 nM
|
|
|
|
CP0411913
|
5-amino-2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
|
C18H16N6O2
|
1
|
| 1 |
Ki = 11.1 nM
|
|
|
|
CP0470345
|
2-(furan-2-yl)-5-(4-methoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
|
C16H12N4O2S
|
1
|
| 1 |
Ki = 11.2 nM
|
|
|
|
CP0473053
|
N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]-3-(4-phenylpiperazin-1-yl)propanamide
Show/Hide
|
C30H30N8O2
|
1
|
| 1 |
Ki = 11.8 nM
|
|
|
|
CP0393765
|
11-(furan-2-yl)-3-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
|
C13H13N7O
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0130086
|
8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
|
C20H24N4O4
|
4
|
| 1 |
Ki = 12 nM
|
|
|
| 2 |
Ki = 36 nM
|
|
|
| 3 |
Ki = 90.8 nM
|
|
|
| 4 |
Ki = 91.2 nM
|
|
|
|
CP0396853
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2-(furan-2-yl)-N-methyl-5-[(2-phenylacetyl)amino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C19H16N6O3
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1
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| 1 |
Ki = 12.4 nM
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CP0420227
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US9018371, 15
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C16H15BrClN5O3
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1
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| 1 |
Ki = 13 nM
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CP0391516
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(2-methoxyphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C19H17N5O4
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1
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| 1 |
Ki = 13.2 nM
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CP0425052
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(thiophen-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C16H19N5O5S
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1
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| 1 |
Ki = 13.3 nM
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CP0868036
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8-(Furan-2-yl)-N2-phenethyl-9-propyl-9H-purine-2,6-diamine
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C20H22N6O
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1
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| 1 |
Ki = 14 nM
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CP0448052
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3-[[7-amino-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]methyl]phenol
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C17H15N5O2
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1
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| 1 |
Ki = 14 nM
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CP0391519
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(3-methoxyphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C19H17N5O4
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1
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| 1 |
Ki = 14.9 nM
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CP0436905
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8-amino-6-[4-(2-aminoethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
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C19H18N6O2
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1
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| 1 |
Ki = 14.9 nM
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CP0460451
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N-[4-(furan-2-yl)-11-methyl-12-methylsulfanyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-(4-methoxyphenyl)acetamide
Show/Hide
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C21H19N7O3S
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1
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| 1 |
Ki = 15 nM
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CP0406006
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3-[6-amino-8-(furan-2-yl)purin-9-yl]propan-1-ol
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C12H13N5O2
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1
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| 1 |
Ki = 15 nM
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CP0375195
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5-amino-2-(furan-2-yl)-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C11H10N6O2
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1
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| 1 |
Ki = 15 nM
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CP0133515
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9-(5'-Cyclopropylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-(3-iodo-benzyl)adenine
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C20H21IN6O3S
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1
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| 1 |
Ki = 15.2 nM
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CP0385864
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5-N-benzyl-7-N-cyclohexyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki = 15.2 nM
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CP0387252
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(3-chlorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C18H14ClN5O3
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1
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| 1 |
Ki = 15.7 nM
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CP0424404
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3-(furan-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4-one
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C21H16N4O2
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1
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| 1 |
Ki = 15.8 nM
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CP0862927
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1-(9-Ethylamino-2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea hydrochloride
Show/Hide
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C21H22ClN9O3
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1
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| 1 |
Ki = 16 nM
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CP0451425
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3-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]phenol
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C17H15N5O2S
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1
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| 1 |
Ki = 16 nM
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CP0425051
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(naphthalen-2-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
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C22H23N5O5
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1
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| 1 |
Ki = 16.1 nM
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CP0387021
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8-amino-6-(4-hydroxy-2-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
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C18H15N5O3
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1
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| 1 |
Ki = 16.8 nM
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CP0392049
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11-(furan-2-yl)-4-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-amine
Show/Hide
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C13H13N7O
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1
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| 1 |
Ki = 17 nM
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CP0402920
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2-[[7-amino-5-(furan-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]methyl]phenol
Show/Hide
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C16H13N5O2
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1
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| 1 |
Ki = 17 nM
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CP0420605
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2-(furan-2-yl)-5-N-[2-(3-methoxyphenyl)ethyl]-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5O2S
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1
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| 1 |
Ki = 17 nM
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CP0446614
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2-(furan-2-yl)-5-N-propyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C12H13N5OS
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1
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| 1 |
Ki = 17 nM
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CP0405999
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8-(furan-2-yl)-9-propylpurin-6-amine
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C12H13N5O
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1
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| 1 |
Ki = 18 nM
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CP0391518
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N-benzyl-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C18H16N6O2
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1
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| 1 |
Ki = 18.6 nM
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CP0470336
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2,5-diphenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
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C17H12N4S
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1
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| 1 |
Ki = 19 nM
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CP0409832
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US9018371, 7
Show/Hide
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C17H18ClN5O3S
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1
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| 1 |
Ki = 19.9 nM
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CP0316241
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2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
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C10H7N7O
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1
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| 1 |
Ki = 20 nM
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CP0316519
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(2S,3S,4R,5R)-5-(2-chloro-6-(methylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrothiophene-2-carboxamide
Show/Hide
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C12H15ClN6O3S
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1
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| 1 |
Ki = 20 nM
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CP0403543
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4-(furan-2-yl)-11-methyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C12H10N6O
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1
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| 1 |
Ki = 20 nM
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CP0462700
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1-[11-(furan-2-yl)-3-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H20N8O3
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1
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| 1 |
Ki = 20 nM
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CP0411545
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5-N-[(2-methoxyphenyl)methyl]-2-(5-methylfuran-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5O2S
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1
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| 1 |
Ki = 20 nM
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CP0510816
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4-amino-2-(4-fluoro-phenyl)-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
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C15H10FN5O
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1
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| 1 |
Ki = 20.1 nM
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CP0385367
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5-N,7-N-dibenzyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C22H19N7O
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1
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| 1 |
Ki = 20.4 nM
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CP0409379
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1-(9-Ethylamino-2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C21H21N9O3
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1
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| 1 |
Ki = 21 nM
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CP0416700
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(3-methylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 21 nM
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CP0434928
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(4-ethylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H19N5O3
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1
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| 1 |
Ki = 21 nM
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CP0493754
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5-N-benzyl-7-N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C22H18FN7O
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1
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| 1 |
Ki = 21.8 nM
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CP0425843
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2-Furan-2-yl-9-methylsulfanyl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C20H19N7OS
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1
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| 1 |
Ki = 22 nM
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CP0482181
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5-N-[(3-methoxyphenyl)methyl]-2-thiophen-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C17H15N5OS2
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1
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| 1 |
Ki = 22 nM
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CP0427859
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5-(5-methylfuran-2-yl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
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C16H12N4OS
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1
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| 1 |
Ki = 22.4 nM
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CP0431393
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1-Ethyl-8-(4-(4-(4-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H25F3N6O4S
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1
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| 1 |
Ki = 22.7 nM
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CP0436899
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8-amino-6-(4-aminophenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H14N6O
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1
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| 1 |
Ki = 22.9 nM
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CP0385872
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N-[5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C22H23N7O2
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1
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| 1 |
Ki = 23.6 nM
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CP0434927
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(2-bromophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14BrN5O3
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1
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| 1 |
Ki = 24.3 nM
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CP0524582
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US9018371, 8
Show/Hide
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C20H18ClN5O2S
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1
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| 1 |
Ki = 24.8 nM
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CP0419834
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5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C20H20N6O4
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1
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| 1 |
Ki = 25.8 nM
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CP0387020
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2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]acetamide
Show/Hide
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C19H16N6O3
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1
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| 1 |
Ki = 26 nM
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CP0850612
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8-Bromo-N2-phenethyl-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C16H19BrN6
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1
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| 1 |
Ki = 27 nM
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CP0542206
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2-(furan-2-yl)-5-[(2-phenylacetyl)amino]-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C26H22N6O3
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1
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| 1 |
Ki = 28.1 nM
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CP0380866
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ethyl 5-(cyclobutylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C16H17N5O3
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1
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| 1 |
Ki = 28.9 nM
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CP0421969
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(2R,3R,4S,5R)-2-[6-amino-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C19H19N5O5
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1
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| 1 |
Ki = 29 nM
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CP0394483
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(6-chloro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21ClN6O5
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1
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| 1 |
Ki = 29.3 nM
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CP0391517
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2-(furan-2-yl)-5-(methylamino)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C19H18N6O2
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1
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| 1 |
Ki = 29.7 nM
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CP0401401
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4-(furan-2-yl)-11-propyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H14N6O
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1
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| 1 |
Ki = 30 nM
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CP0561741
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N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-3-(3,4-dihydro-1H-isoquinolin-2-yl)propanamide
Show/Hide
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C27H23N3O4
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1
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| 1 |
Ki = 30 nM
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CP0396829
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ethyl 5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 32 nM
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CP0394627
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(2-chlorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14ClN5O3
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1
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| 1 |
Ki = 32 nM
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CP0394626
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(3-fluorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14FN5O3
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1
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| 1 |
Ki = 32.5 nM
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CP0403757
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8-[4-(phenylethylamidosulfonyl)phenyl]-1,3-dimethylxanthine
Show/Hide
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C21H21N5O4S
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1
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| 1 |
Ki = 32.6 nM
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CP0847643
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3-(2-furyl)[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-one
Show/Hide
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C13H8N4O2
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1
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| 1 |
Ki = 33 nM
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CP0406001
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2-[6-amino-8-(furan-2-yl)purin-9-yl]ethanol
Show/Hide
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C11H11N5O2
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1
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| 1 |
Ki = 33 nM
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CP0455822
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3-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)benzonitrile
Show/Hide
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C18H11N5S
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1
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| 1 |
Ki = 33.6 nM
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CP0411544
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2-(5-methylfuran-2-yl)-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C15H13N5OS2
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1
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| 1 |
Ki = 34 nM
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CP0424470
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8-[4-[4-(4-chloro-3-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H27ClN6O5S
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1
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| 1 |
Ki = 35.3 nM
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CP0549758
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2-amino-4-[4-(3-piperidin-1-ylpropoxy)phenyl]indeno[1,2-d]pyrimidin-5-one
Show/Hide
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C25H26N4O2
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1
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| 1 |
Ki = 35.5 nM
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CP0871535
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N2-Benzyl-8-bromo-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C15H17BrN6
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1
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| 1 |
Ki = 36 nM
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CP0394639
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(2-methylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 37.2 nM
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CP0463482
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ethyl 5-(cyclopropylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C15H15N5O3
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1
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| 1 |
Ki = 37.4 nM
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CP0409656
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2-[[7-amino-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]methyl]phenol
Show/Hide
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C17H15N5O2
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1
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| 1 |
Ki = 38 nM
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CP0433836
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6-[4-[2-[4-(2-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H34ClN5O4
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1
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| 1 |
Ki = 38.02 nM
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CP0175614
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8-(3-chlorostyryl)caffeine
Show/Hide
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C16H15ClN4O2
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1
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| 1 |
Ki = 38.1 nM
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CP0414839
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4-(furan-2-yl)-11-methyl-N-[(1R)-1-phenylethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 38.2 nM
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CP0394634
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2-(furan-2-yl)-5-(methylamino)-N-(2-phenoxyethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C19H18N6O3
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1
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| 1 |
Ki = 38.2 nM
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CP0448421
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(2S,3S,4R,5R)-5-[6-amino-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C21H22N6O5
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1
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| 1 |
Ki = 39 nM
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CP0435935
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2,6-diphenyl-1-deazapurine
Show/Hide
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C18H13N3
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1
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| 1 |
Ki = 39 nM
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CP0380865
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ethyl 5-[(4-fluorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C19H16FN5O3
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1
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| 1 |
Ki = 39.3 nM
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CP0156252
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N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
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C18H16N2O2S
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1
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| 1 |
Ki = 39.5 nM
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CP0425056
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2-(3''-(4''-bromo-indolyl)ethyloxy)adenosine
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C20H21BrN6O5
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1
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| 1 |
Ki = 39.7 nM
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CP0446616
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4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]benzene-1,2-diol
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C17H15N5O3S
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1
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| 1 |
Ki = 40 nM
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CP0466568
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2,7-bis(furan-2-yl)-1,3-benzoxazol-5-amine
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C15H10N2O3
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1
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| 1 |
Ki = 40 nM
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CP0444679
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8-[4-[4-(4-chloro-3-hydroxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C24H25ClN6O5S
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1
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| 1 |
Ki = 40.7 nM
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CP0472358
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-3-sulfamoylbenzamide
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C22H23N7O4S2
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1
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| 1 |
Ki = 41 nM
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CP0387255
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ethyl 2-(furan-2-yl)-5-(2-phenylhydrazinyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C18H16N6O3
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1
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| 1 |
Ki = 41.8 nM
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CP0452389
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11-(furan-2-yl)-3-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
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C18H15N7O
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1
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| 1 |
Ki = 42 nM
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CP0572608
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US9018371, 16
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C16H15ClIN5O3
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1
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| 1 |
Ki = 42.9 nM
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CP0394224
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]-6-(propan-2-ylamino)purin-9-yl]oxolane-3,4-diol
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C22H25N5O5
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1
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| 1 |
Ki = 43 nM
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CP0480188
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ethyl 5-(cyclopentylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C17H19N5O3
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1
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| 1 |
Ki = 43.4 nM
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CP0493753
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5-N,7-N-bis[(4-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
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C22H17F2N7O
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1
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| 1 |
Ki = 43.6 nM
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CP0375538
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4-[4-[(4-chlorophenyl)methyl]piperazine-1-carbonyl]-N-(4-oxo-3,1-benzothiazin-2-yl)benzamide
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C27H23ClN4O3S
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1
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| 1 |
Ki = 44.3 nM
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CP0414535
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ethyl 2-(furan-2-yl)-5-(2-methylpropylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C16H19N5O3
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1
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| 1 |
Ki = 44.4 nM
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CP0133196
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8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
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C14H15N7O
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1
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| 1 |
Ki = 45 nM
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CP0425053
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(2R,3R,4S,5R)-2-(2-(2-(1H-indol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
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C20H22N6O5
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1
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| 1 |
Ki = 45 nM
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CP0458577
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8-amino-6-(4-hydroxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
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C17H13N5O2
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1
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| 1 |
Ki = 45 nM
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CP0473052
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8-amino-2-phenyl-6-[4-(2-piperidin-1-ylethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazin-3-one
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C24H26N6O2
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1
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| 1 |
Ki = 45.4 nM
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CP0412572
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4-(furan-2-yl)-11-methyl-N-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
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C19H17N7O
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1
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| 1 |
Ki = 46.1 nM
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CP0387251
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N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C18H15FN6O2
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1
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| 1 |
Ki = 47.6 nM
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CP0388498
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8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phenyl)-1-ethyl-3,7-dihydropurine-2,6-dione
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C23H23ClN6O4S
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1
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| 1 |
Ki = 48.4 nM
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CP0412425
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1,3-bis(cyclopropylmethyl)-6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C32H35N5O4
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1
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| 1 |
Ki = 48.98 nM
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CP0385869
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2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
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C9H9N7O
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1
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| 1 |
Ki = 49.3 nM
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CP0401423
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N-[4-(furan-2-yl)-11-methyl-12-methylsulfanyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-[4-(2-methylpropyl)phenyl]acetamide
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C24H25N7O2S
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1
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| 1 |
Ki = 50 nM
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CP0430162
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2-(4-(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)phenylsulfonamido)acetic acid
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C20H18N8O5S
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1
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| 1 |
Ki = 50 nM
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CP0447319
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N-[4-(furan-2-yl)-11-methyl-12-methylsulfanyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-[4-(2-methylpropoxy)phenyl]acetamide
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C24H25N7O3S
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1
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| 1 |
Ki = 50 nM
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CP0395752
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4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C20H18N6O
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1
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| 1 |
Ki = 50 nM
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CP0406004
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2-(4-phenylmethoxyphenyl)acetamide
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C25H21N5O3
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1
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| 1 |
Ki = 50 nM
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CP0396869
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ethyl 2-(furan-2-yl)-5-(pentylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C17H21N5O3
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1
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| 1 |
Ki = 50.1 nM
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CP0396836
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ethyl 5-(ethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C14H15N5O3
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1
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| 1 |
Ki = 50.3 nM
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CP0455004
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4-amino-2-p-tolyl-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
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C16H13N5O
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1
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| 1 |
Ki = 50.6 nM
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CP0399804
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10-(4-chlorophenyl)-3-(furan-2-yl)-[1,2,4]triazino[4,3-a]benzimidazol-4-one
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C19H11ClN4O2
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1
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| 1 |
Ki = 50.6 nM
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CP0410466
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11-benzyl-4-phenyl-13-thiophen-2-yl-5,6,8,11,12-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7,12-pentaen-10-one
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C25H17N5OS
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1
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| 1 |
Ki = 51 nM
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CP0448053
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2-[(3-fluorophenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
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C17H14FN5O
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1
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| 1 |
Ki = 51 nM
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CP0480186
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2-(furan-2-yl)-5-(phenylcarbamoylamino)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C25H21N7O3
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1
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| 1 |
Ki = 51.4 nM
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CP0257633
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(2R,3S,4R,5R)-2-Aminomethyl-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol
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C10H14N6O3
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5
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| 1 |
Ki = 52 nM
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| 2 |
Ki = 407 nM
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| 3 |
Ki = 492 nM
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| 4 |
Ki = 534 nM
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| 5 |
Ki = 604 nM
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CP0406008
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8-Bromo-9-ethyl-9H-adenine
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C7H8BrN5
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1
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| 1 |
Ki = 52 nM
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CP0882748
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5-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)pentyl-ammonium chloride
Show/Hide
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C16H21ClN8O
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1
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| 1 |
Ki = 52.6 nM
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CP0420864
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4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)-N,N-dimethylbenzenesulfonamide
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C16H19N5O4S
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1
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| 1 |
Ki = 52.7 nM
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CP0427862
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[3-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)phenyl]methanol
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C18H14N4OS
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1
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| 1 |
Ki = 53 nM
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CP0468028
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7-(4-aminophenethyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C18H16N8O
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1
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| 1 |
Ki = 55 nM
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CP0499430
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4-(furan-2-yl)-11-methyl-N-[(1S)-1-phenylethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 55.2 nM
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CP0018686
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(2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylamino)-purin-9-yl]-tetrahydro-furan-2-carboxylic acid methylamide
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C18H19IN6O4
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2
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| 1 |
Ki = 56 nM
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| 2 |
Ki = 2900 nM
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CP0383505
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(2R,3R,4S,5R)-2-(2-(4-fluorophenethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C18H20FN5O5
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1
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| 1 |
Ki = 56.8 nM
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CP0523028
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1-[8-(furan-2-yl)-9-methylpurin-6-yl]-3-phenylurea
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C17H14N6O2
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1
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| 1 |
Ki = 57 nM
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CP0402918
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2-[(2-fluorophenyl)methyl]-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C17H14FN5O
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1
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| 1 |
Ki = 57 nM
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CP0525979
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2-[4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]piperidin-1-yl]-N-[(4-sulfamoylphenyl)methyl]acetamide
Show/Hide
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C24H28N8O4S2
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1
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| 1 |
Ki = 57 nM
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CP0081315
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9-(5'-Ethylaminocarbonyl-4-thio-beta-D-ribofuranosyl)-N6-(3-iodo-benzyl)adenine
Show/Hide
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C19H21IN6O3S
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1
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| 1 |
Ki = 57.6 nM
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CP0446613
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2-(furan-2-yl)-5-N-(3-phenylpropyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5OS
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1
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| 1 |
Ki = 58 nM
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CP0405752
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(2R,3R,4S,5R)-2-(2-(2-fluorophenethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C18H20FN5O5
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1
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| 1 |
Ki = 58.1 nM
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CP0420750
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4-[4-[(3-chlorophenyl)methyl]piperazine-1-carbonyl]-N-(4-oxo-3,1-benzothiazin-2-yl)benzamide
Show/Hide
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C27H23ClN4O3S
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1
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| 1 |
Ki = 58.3 nM
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CP0380871
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ethyl 5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H21N5O3
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1
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| 1 |
Ki = 58.9 nM
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CP0508063
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(S)-5-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzo[d][1,3]dioxole-2-carboxylic acid
Show/Hide
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C21H17N7O5
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1
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| 1 |
Ki = 59 nM
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CP0540372
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2,2-diphenylacetamide
Show/Hide
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C24H19N5O2
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1
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| 1 |
Ki = 59 nM
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CP0391509
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N-[(4-chlorophenyl)methyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C18H15ClN6O2
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1
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| 1 |
Ki = 59.4 nM
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CP0376341
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1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-pyridin-4-yl-urea
Show/Hide
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C17H13N9O2
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1
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| 1 |
Ki = 60 nM
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CP0516849
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2-[4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]piperidin-1-yl]-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
Show/Hide
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C25H30N8O4S2
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1
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| 1 |
Ki = 60 nM
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CP0376058
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2-Benzo[1,3]dioxol-5-yl-N-(9-ethylamino-2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-acetamide
Show/Hide
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C22H20N8O4
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1
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| 1 |
Ki = 61 nM
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CP0534944
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N-benzhydryl-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C24H20N6O2
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1
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| 1 |
Ki = 61.6 nM
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CP0386799
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(4-methylphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 62.2 nM
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CP0420746
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(E)-3-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)prop-2-enamide
Show/Hide
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C18H14N2O3S
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1
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| 1 |
Ki = 62.4 nM
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CP0391522
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ethyl 2-(furan-2-yl)-5-hydrazinyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C12H12N6O3
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1
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| 1 |
Ki = 63.1 nM
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CP0395216
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(2R,3R,4S,5R)-2-[6-(ethylamino)-2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C21H23N5O5
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1
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| 1 |
Ki = 64 nM
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CP0381327
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N-[(3,4-dimethoxyphenyl)methyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C20H19N7O3
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1
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| 1 |
Ki = 64.1 nM
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CP0385870
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2-(furan-2-yl)-5-N-propan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C11H13N7O
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1
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| 1 |
Ki = 64.8 nM
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CP0365871
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3-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)propanamide
Show/Hide
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C18H16N2O3S
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1
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| 1 |
Ki = 64.9 nM
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CP0045162
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1-(2-(furan-2-yl)-8-isopentyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C23H24N8O3
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1
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| 1 |
Ki = 65 nM
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CP0414331
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5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C27H26N6O4
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1
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| 1 |
Ki = 65.2 nM
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CP0485804
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4-amino-8-chloro-2-(4-chloro-phenyl)-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
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C15H9Cl2N5O
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1
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| 1 |
Ki = 67.5 nM
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CP0427816
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1-[11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C19H16N8O3
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1
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| 1 |
Ki = 68 nM
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CP0375279
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11-benzyl-4-phenyl-13-thiophen-3-yl-5,6,8,11,12-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7,12-pentaen-10-one
Show/Hide
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C25H17N5OS
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1
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| 1 |
Ki = 69.2 nM
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CP0383507
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(2R,3R,4S,5R)-2-(2-(3-fluorophenethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C18H20FN5O5
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1
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| 1 |
Ki = 69.3 nM
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CP0431394
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1-Ethyl-8-(4-(4-(3-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H25F3N6O4S
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1
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| 1 |
Ki = 69.4 nM
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CP0457542
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2-mercaptopyrimidine analogue, 5h
Show/Hide
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C13H21N3O2S
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1
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| 1 |
Ki = 71 nM
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CP0467705
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2-(furan-2-yl)-7-thiophen-2-yl-1,3-benzoxazol-5-amine
Show/Hide
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C15H10N2O2S
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1
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| 1 |
Ki = 71 nM
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CP0391514
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(4-fluorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14FN5O3
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1
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| 1 |
Ki = 71.5 nM
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CP0391515
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(4-chlorophenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H14ClN5O3
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1
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| 1 |
Ki = 71.9 nM
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CP0414339
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ethyl 5-[(4-chlorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H16ClN5O3
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1
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| 1 |
Ki = 73.2 nM
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CP0399761
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8-Bromo-9-isopropyl-9H-adenine
Show/Hide
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C8H10BrN5
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1
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| 1 |
Ki = 74 nM
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CP0405391
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6-[4-[2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C29H32Cl2N6O4
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1
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| 1 |
Ki = 74.13 nM
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CP0375421
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N-[4-phenyl-5-(pyridine-2-carbonyl)-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C20H13N3O3S
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1
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| 1 |
Ki = 74.7 nM
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CP0430145
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5-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzo[d][1,3]dioxole-4-sulfonic acid
Show/Hide
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C20H17N7O6S
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1
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| 1 |
Ki = 75 nM
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CP0381296
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N-[(4-chlorophenyl)methyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H14ClN7O
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1
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| 1 |
Ki = 75.4 nM
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CP0410464
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11-benzyl-13-cyclopentyl-4-phenyl-5,6,8,11,12-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7,12-pentaen-10-one
Show/Hide
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C26H23N5O
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1
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| 1 |
Ki = 75.5 nM
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CP0396538
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4-(furan-2-yl)-N-[2-(1H-indol-3-yl)ethyl]-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H18N8O
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1
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| 1 |
Ki = 77 nM
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CP0420801
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8-[4-[4-[(4-bromophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H27BrN6O4S
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1
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| 1 |
Ki = 77.8 nM
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CP0471115
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8-amino-2-(4-methoxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O2
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1
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| 1 |
Ki = 78 nM
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CP0408873
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2-methyl-5-N-(2-phenylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C14H15N5S
|
1
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| 1 |
Ki = 78 nM
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CP0446802
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5-N-[(2-methoxyphenyl)methyl]-2-pyrazin-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C17H15N7OS
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1
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| 1 |
Ki = 79 nM
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CP0414539
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1-[3-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)anilino]-3-oxopropyl]piperidine-4-carboxamide
Show/Hide
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C26H28N8O3
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1
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| 1 |
Ki = 79.2 nM
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CP0220980
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1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C22H22N8O3
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1
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| 1 |
Ki = 80 nM
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CP0426317
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2-(furan-2-yl)pyrazolo[1,5-c]quinazolin-5-amine
Show/Hide
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C14H10N4O
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1
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| 1 |
Ki = 80 nM
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CP0868038
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N-benzyl-8-(furan-2-yl)-9-propyl-9H-purin-6-amine
Show/Hide
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C19H19N5O
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1
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| 1 |
Ki = 80 nM
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CP0366079
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N-(4-oxo-3,1-benzothiazin-2-yl)-3-phenylpropanamide
Show/Hide
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C17H14N2O2S
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1
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| 1 |
Ki = 80.9 nM
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CP0482612
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N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-3-piperidin-1-ylpropanamide
Show/Hide
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C23H23N3O4
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1
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| 1 |
Ki = 81 nM
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CP0394625
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2-(furan-2-yl)-N-[(4-methoxyphenyl)methyl]-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C19H18N6O3
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1
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| 1 |
Ki = 81.3 nM
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CP0427860
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[4-(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)phenyl]methanol
Show/Hide
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C18H14N4OS
|
1
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| 1 |
Ki = 82 nM
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CP0303994
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N-(4-oxothieno[2,3-d][1,3]thiazin-2-yl)-4-phenylbutanamide
Show/Hide
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C16H14N2O2S2
|
1
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| 1 |
Ki = 82.5 nM
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CP0490809
|
2-(4-Chlorophenyl)-7-ethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C14H12ClN7
|
1
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| 1 |
Ki = 83.8 nM
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CP0381328
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N-cyclobutyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C15H15N7O
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1
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| 1 |
Ki = 83.9 nM
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CP0394984
|
8-Bromo-9-(3-hydroxypropyl)-9H-adenine
Show/Hide
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C8H10BrN5O
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1
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| 1 |
Ki = 85 nM
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CP0538564
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8-amino-6-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C24H27N7O2
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1
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| 1 |
Ki = 85.2 nM
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CP0376218
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4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzonitrile
Show/Hide
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C20H16N8O
|
1
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| 1 |
Ki = 86 nM
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CP0472319
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4-[4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]piperazin-1-yl]benzenesulfonamide
Show/Hide
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C21H24N8O3S2
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1
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| 1 |
Ki = 86 nM
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CP0411132
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propan-2-yl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C14H15N5O3
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1
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| 1 |
Ki = 86.5 nM
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CP0385863
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1-[2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
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C18H18N8O2
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1
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| 1 |
Ki = 86.9 nM
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CP0340021
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4-[[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]methyl]benzenesulfonamide
Show/Hide
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C16H14N6O3S2
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1
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| 1 |
Ki = 87 nM
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CP0388112
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N-[(4-fluorophenyl)methyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H14FN7O
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1
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| 1 |
Ki = 87.5 nM
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CP0376135
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N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)benzamide
Show/Hide
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C22H15N5O2
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1
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| 1 |
Ki = 88.2 nM
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CP0387973
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2-[4-[(4-methylphenyl)methoxy]phenyl]acetamide
Show/Hide
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C26H23N5O3
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1
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| 1 |
Ki = 89 nM
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CP0489426
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2-[(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)methyl]phenol
Show/Hide
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C18H15N5O
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1
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| 1 |
Ki = 89 nM
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CP0382858
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2-[7-amino-5-(furan-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]phenol
Show/Hide
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C15H11N5O2
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1
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| 1 |
Ki = 89 nM
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CP0538263
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8-[4-[4-(2-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25BrN6O4S
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1
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| 1 |
Ki = 89.5 nM
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CP0530665
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7-(3,4-dimethoxyphenyl)-2-(furan-2-yl)-1,3-benzoxazol-5-amine
Show/Hide
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C19H16N2O4
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1
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| 1 |
Ki = 90 nM
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CP0561742
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N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-3-morpholin-4-ylpropanamide
Show/Hide
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C22H21N3O5
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1
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| 1 |
Ki = 90 nM
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CP0446155
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(2R,3R,4S,5R)-2-[2-[2-(2-hydroxycyclohexyl)ethynyl]-6-(methoxyamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C19H25N5O6
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1
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| 1 |
Ki = 91 nM
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CP0405925
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2-Phenyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine
Show/Hide
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C16H12N4
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1
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| 1 |
Ki = 91 nM
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CP0381298
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N-benzyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H15N7O
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1
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| 1 |
Ki = 91 nM
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CP0510734
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5-N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C19H19N5O3S
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1
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| 1 |
Ki = 91 nM
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CP0560042
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8-amino-6-[4-(2-hydroxy-3-piperidin-1-ylpropoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C25H28N6O3
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1
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| 1 |
Ki = 91.7 nM
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CP0375530
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(E)-4-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)but-3-enamide
Show/Hide
|
C19H16N2O3S
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1
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| 1 |
Ki = 91.8 nM
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CP0377680
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1-Ethyl-8-(4-(4-(4-fluorobenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25FN6O4S
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1
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| 1 |
Ki = 92 nM
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CP0424466
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8-[4-[4-[(3-bromophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H27BrN6O4S
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1
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| 1 |
Ki = 92.4 nM
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CP0381326
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N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C21H21N7O3
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1
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| 1 |
Ki = 92.5 nM
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CP0383050
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2-amino-6-[(3-cyanophenyl)methylsulfanyl]-4-(furan-2-yl)pyridine-3,5-dicarbonitrile
Show/Hide
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C19H11N5OS
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1
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| 1 |
Ki = 93 nM
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CP0405375
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6-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C29H32N4O4
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1
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| 1 |
Ki = 93.33 nM
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CP0420804
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8-[4-[4-(3-chloro-4-hydroxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25ClN6O5S
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1
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| 1 |
Ki = 93.8 nM
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CP0885708
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2-[6-Ethylamino-2-(3-hydroxy-3-phenyl-prop-1-ynyl)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C21H23N5O5
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1
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| 1 |
Ki = 94 nM
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CP0397330
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N-(1-benzylpiperidin-4-yl)-4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)benzenesulfonamide
Show/Hide
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C26H30N6O4S
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1
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| 1 |
Ki = 94.5 nM
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CP0479030
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8-amino-2-phenyl-6-(3,4,5-trihydroxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O4
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1
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| 1 |
Ki = 94.5 nM
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CP0092135
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1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chloro-phenyl)-urea
Show/Hide
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C21H19ClN8O2
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1
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| 1 |
Ki = 95 nM
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CP0425050
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(2R,3R,4S,5R)-2-(2-(2-(1H-pyrrol-3-yl)ethoxy)-6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C16H20N6O5
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1
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| 1 |
Ki = 95 nM
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CP0269239
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(2S,3S,4R,5R)-3,4-Dihydroxy-5-{6-[3-(4-sulfamoyl-phenyl)-ureido]-purin-9-yl}-tetrahydro-furan-2-carboxylic acid ethylamide
Show/Hide
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C19H22N8O7S
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1
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| 1 |
Ki = 95.2 nM
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CP0468151
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N-[5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C22H17N7O2
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1
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| 1 |
Ki = 95.2 nM
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CP0859556
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2-Hydroxymethyl-5-[2-(3-hydroxy-3-phenyl-prop-1-ynyl)-6-isopropylamino-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
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C22H25N5O5
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1
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| 1 |
Ki = 96 nM
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CP0490671
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1-Benzyl-3-prop-2-ynyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C19H14N4O2
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1
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| 1 |
Ki = 96 nM
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CP0376871
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1-(2-phenethyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-phenylurea
Show/Hide
|
C26H22N6O
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1
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| 1 |
Ki = 96 nM
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CP0519957
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4-[2-[(7-amino-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-5-yl)amino]ethyl]phenol
Show/Hide
|
C19H17N5OS
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1
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| 1 |
Ki = 96 nM
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CP0434145
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methyl 3-[[6-amino-3,5-dicyano-4-(furan-3-yl)pyridin-2-yl]sulfanylmethyl]benzoate
Show/Hide
|
C20H14N4O3S
|
1
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| 1 |
Ki = 96 nM
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CP0424433
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8-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H26N6O5S
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1
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| 1 |
Ki = 96.7 nM
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CP0405410
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N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-4-piperidin-1-ylbutanamide
Show/Hide
|
C24H25N3O4
|
1
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| 1 |
Ki = 98 nM
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CP0398543
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5-(5-methylfuran-2-yl)-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C16H13N5O
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1
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| 1 |
Ki = 99 nM
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CP0488973
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1-[2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-3-phenylurea
Show/Hide
|
C16H14N8O2
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1
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| 1 |
Ki = 99.6 nM
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CP0462060
|
4-(2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl)benzenesulfonic acid
Show/Hide
|
C18H15N7O4S
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1
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| 1 |
Ki = 100 nM
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CP0849514
|
1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(pyridin-4-yl)urea hydrochloride
Show/Hide
|
C17H14ClN9O2
|
1
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| 1 |
Ki = 100 nM
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CP0391513
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2-(furan-2-yl)-5-(methylamino)-N-[(4-methylphenyl)methyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C19H18N6O2
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1
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| 1 |
Ki = 100 nM
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CP0250678
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1-(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C27H24N8O3
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1
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| 1 |
Ki = 101 nM
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CP0388501
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8-(4-(4-Benzo[1,3]dioxol-5-ylmethylpiperazine-1-sulfonyl)phenyl)-1-ethyl-3,7-dihydropurine-2,6-dione
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C25H26N6O6S
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1
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| 1 |
Ki = 102 nM
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CP0490037
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2-[3-(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)propyl]phenol
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C20H19N5O
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1
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| 1 |
Ki = 102 nM
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CP0445856
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7-pyrrolidin-1-yl-N-(3,4,5-trimethoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C18H21N5O3S
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1
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| 1 |
Ki = 102 nM
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CP0463478
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ethyl 2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C15H17N5O3
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1
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| 1 |
Ki = 103 nM
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CP0396850
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ethyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C13H13N5O3
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1
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| 1 |
Ki = 104 nM
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CP0427866
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N-(2,5-diphenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
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C24H16N4OS
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1
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| 1 |
Ki = 104 nM
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CP0546060
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2-amino-4-phenyl-7-(3-pyrrolidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
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C24H24N4O2
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1
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| 1 |
Ki = 104 nM
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CP0333181
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1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
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C25H19ClN8O2
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1
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| 1 |
Ki = 105 nM
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CP0471646
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1-[8-(furan-2-yl)-9-methylpurin-6-yl]-3-(4-methylphenyl)urea
Show/Hide
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C18H16N6O2
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1
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| 1 |
Ki = 106 nM
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CP0373202
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1,3-dimethyl-6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H27N5O4
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1
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| 1 |
Ki = 107.15 nM
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CP0426877
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9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-methyladenine
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C15H20N6O3S
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1
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| 1 |
Ki = 108 nM
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CP0424467
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8-[4-[4-(4-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C24H25FN6O4S
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1
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| 1 |
Ki = 108 nM
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CP0383003
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2-amino-4-(furan-2-yl)-6-(pyridin-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
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C17H11N5OS
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1
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| 1 |
Ki = 108 nM
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CP0376844
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6-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]hexan-1-ol
Show/Hide
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C17H21N7O2
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1
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| 1 |
Ki = 109 nM
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CP0470334
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5-(3-methoxyphenyl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
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C18H14N4OS
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1
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| 1 |
Ki = 109.8 nM
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CP0316242
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1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-methyl-but-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
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C22H19ClN8O2
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1
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| 1 |
Ki = 110 nM
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CP0419073
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N-(3-benzyl-5-phenyltriazolo[4,5-d]pyrimidin-7-yl)cyclopropanecarboxamide
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C21H18N6O
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1
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| 1 |
Ki = 110 nM
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CP0382857
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5-benzyl-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
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C18H15N5
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1
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| 1 |
Ki = 110 nM
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CP0406005
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-2-phenylacetamide
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C18H15N5O2
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1
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| 1 |
Ki = 110 nM
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CP0377681
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8-(4-(4-Benzo[1,3]dioxol-5-ylmethylpiperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
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C26H28N6O6S
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1
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| 1 |
Ki = 112 nM
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CP0400897
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5-N-cyclohexyl-7-N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C21H22FN7O
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1
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| 1 |
Ki = 112 nM
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CP0414840
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N-cyclopropyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H13N7O
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1
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| 1 |
Ki = 113 nM
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CP0860138
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8-(Furan-2-yl)-N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine
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C21H24N6O
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1
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| 1 |
Ki = 113 nM
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CP0385358
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N-cyclohexyl-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
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C20H20N6O2
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1
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| 1 |
Ki = 113 nM
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CP0372528
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2,6-dphenyl-8-propyl-1-deazapurine
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C21H19N3
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1
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| 1 |
Ki = 114 nM
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CP0394628
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benzyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C18H15N5O3
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1
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| 1 |
Ki = 114 nM
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CP0383011
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2-amino-4-(furan-2-yl)-6-(pyridin-4-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
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C17H11N5OS
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1
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| 1 |
Ki = 114 nM
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CP0373449
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6-[4-[2-[4-(4-bromophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H26BrN5O4
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1
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| 1 |
Ki = 114.82 nM
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CP0433854
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6-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H34ClN5O4
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1
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| 1 |
Ki = 114.82 nM
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CP0264647
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1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
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C22H21ClN8O2
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1
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| 1 |
Ki = 115 nM
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CP0420744
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4-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)butanamide
Show/Hide
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C19H18N2O3S
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1
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| 1 |
Ki = 115 nM
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CP0391510
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2-phenyl-5-thiophen-2-ylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C15H11N5S
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1
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| 1 |
Ki = 115 nM
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CP0455836
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5-(4-methoxyphenyl)-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
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C18H14N4OS
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1
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| 1 |
Ki = 115.3 nM
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CP0396848
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ethyl 5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C21H21N5O5
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1
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| 1 |
Ki = 116 nM
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CP0456685
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5-N-benzyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H15N5S
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1
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| 1 |
Ki = 116 nM
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CP0381297
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4-(furan-2-yl)-11-methyl-N-[(4-methylphenyl)methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 117 nM
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CP0467043
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(E)-N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbut-3-enamide
Show/Hide
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C18H14N2O2S
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1
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| 1 |
Ki = 118 nM
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CP0404822
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1-Benzyl-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
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C19H18N4O2
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1
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| 1 |
Ki = 119 nM
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CP0493292
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N-(3-benzyl-5-phenyltriazolo[4,5-d]pyrimidin-7-yl)cyclobutanecarboxamide
Show/Hide
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C22H20N6O
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1
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| 1 |
Ki = 119 nM
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CP0463047
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N-cyclohexyl-11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
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C17H19N7O
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1
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| 1 |
Ki = 119 nM
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CP0045165
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1-(2-(furan-2-yl)-8-phenethyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N8O3
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1
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| 1 |
Ki = 120 nM
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CP0381894
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8-Bromo-9-methyl-9H-adenine
Show/Hide
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C6H6BrN5
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1
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| 1 |
Ki = 120 nM
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CP0376596
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5-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzo[d][1,3]dioxole-2,2-dicarboxylic acid
Show/Hide
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C22H17N7O7
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1
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| 1 |
Ki = 120 nM
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CP0485803
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1-benzyl-3-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-urea
Show/Hide
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C23H18N6O2
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1
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| 1 |
Ki = 120.1 nM
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CP0400041
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2-(Phenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidin-5-amine
Show/Hide
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C13H11N7
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1
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| 1 |
Ki = 121 nM
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CP0397427
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4-(furan-2-yl)-11-methyl-N-(2-phenoxyethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O2
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1
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| 1 |
Ki = 121 nM
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CP0480581
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ethyl 5-(cyclohexylmethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H23N5O3
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1
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| 1 |
Ki = 121 nM
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CP0376872
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2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C18H15N5
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1
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| 1 |
Ki = 121.1 nM
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CP0231424
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9-(5'-Cyclobutylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-(3-iodobenzyl)adenine
Show/Hide
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C21H23IN6O3S
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1
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| 1 |
Ki = 122 nM
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CP0385419
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11-(furan-2-yl)-3-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 122 nM
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CP0490590
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ethyl 2-(furan-2-yl)-5-[(4-methylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H19N5O3
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1
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| 1 |
Ki = 122 nM
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CP0420823
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8-[4-(4-phenylpiperazin-1-yl)sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H26N6O4S
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1
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| 1 |
Ki = 122 nM
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CP0473051
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3-[4-(aminomethyl)piperidin-1-yl]-N-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenyl]propanamide
Show/Hide
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C26H30N8O2
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1
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| 1 |
Ki = 123 nM
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CP0397615
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5-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]pentan-1-ol
Show/Hide
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C16H19N7O2
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1
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| 1 |
Ki = 124 nM
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CP0477669
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2-(4-Fluorophenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H16FN7
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1
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| 1 |
Ki = 127 nM
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CP0397161
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4-methoxy-N-[4-phenyl-5-(pyridine-2-carbonyl)-1,3-thiazol-2-yl]benzamide
Show/Hide
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C23H17N3O3S
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1
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| 1 |
Ki = 128 nM
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CP0387990
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1-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C28H25N7O3
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1
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| 1 |
Ki = 130 nM
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CP0397576
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N-cyclopentyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C16H17N7O
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1
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| 1 |
Ki = 130 nM
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CP0469697
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8-[4-[4-[(3-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O5S
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1
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| 1 |
Ki = 131 nM
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CP0412428
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1,3-dimethyl-6-[4-[2-oxo-2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H26F3N5O4
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1
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| 1 |
Ki = 131.83 nM
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CP0464677
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4-(furan-2-yl)-11-methyl-7-pyrrolidin-1-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C15H15N7O
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1
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| 1 |
Ki = 132 nM
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CP0485802
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4-amino-2-phenyl-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
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C15H11N5O
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1
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| 1 |
Ki = 134 nM
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CP0860810
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2-Furan-2-yl-8-methyl-9-(4-methyl-piperazin-1-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine dihydrochloride
Show/Hide
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C16H21Cl2N9O
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1
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| 1 |
Ki = 135 nM
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CP0483127
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5-N-[(2-methoxyphenyl)methyl]-2-methyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C14H15N5OS
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1
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| 1 |
Ki = 135 nM
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CP0561739
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2-(furan-2-yl)-7-pyridin-2-yl-1,3-benzoxazol-5-amine
Show/Hide
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C16H11N3O2
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1
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| 1 |
Ki = 135 nM
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CP0444683
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8-[4-[4-[(4-fluoro-3-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H29FN6O5S
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1
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| 1 |
Ki = 135 nM
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CP0397424
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1-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]propan-2-ol
Show/Hide
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C14H15N7O2
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1
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| 1 |
Ki = 136 nM
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CP0394632
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N-benzhydryl-5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C32H28N6O4
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1
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| 1 |
Ki = 137 nM
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CP0508392
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8-amino-2-(4-hydroxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
Ki = 138 nM
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CP0053428
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1-[4-(furan-2-yl)-11-propyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H20N8O3
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2
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| 1 |
Ki = 140 nM
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| 2 |
Ki = 141 nM
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CP0037176
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(2R,3R,4S,5R)-2-(6-(3-iodobenzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C17H18IN5O4
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1
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| 1 |
Ki = 140 nM
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CP0392763
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4-(3-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propyl)benzenesulfonic acid
Show/Hide
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C19H17N7O4S
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1
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| 1 |
Ki = 140 nM
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CP0425283
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8-[4-[4-(2-methylphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H28N6O4S
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1
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| 1 |
Ki = 140 nM
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CP0542506
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8-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C19H24N6O4S
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1
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| 1 |
Ki = 140 nM
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CP0387250
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N-[(3,4-dimethoxyphenyl)methyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C20H20N6O4
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1
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| 1 |
Ki = 141 nM
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CP0436900
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8-amino-6-(3,5-ditert-butyl-4-methoxyphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C26H31N5O2
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1
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| 1 |
Ki = 141.6 nM
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CP0463483
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ethyl 2-(furan-2-yl)-5-[(4-methoxyphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H19N5O4
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1
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| 1 |
Ki = 142 nM
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CP0549760
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2-amino-4-phenyl-7-(3-piperidin-1-ylpropoxy)indeno[1,2-d]pyrimidin-5-one
Show/Hide
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C25H26N4O2
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1
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| 1 |
Ki = 142 nM
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CP0385868
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7-N-cyclohexyl-2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C15H19N7O
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1
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| 1 |
Ki = 143 nM
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CP0424465
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8-[4-(4-benzoylpiperazin-1-yl)sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H26N6O5S
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1
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| 1 |
Ki = 143 nM
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CP0443526
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1-Ethyl-8-(4-(4-(3-fluorobenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25FN6O4S
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1
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| 1 |
Ki = 144 nM
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CP0411537
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5-N-[(3-methoxyphenyl)methyl]-2-(5-methylfuran-2-yl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C18H17N5O2S
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1
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| 1 |
Ki = 144 nM
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CP0495409
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1-Propyl-8-(4-(4-(4-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H27F3N6O4S
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1
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| 1 |
Ki = 145 nM
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CP0396890
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3-[3-(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)propyl]phenol
Show/Hide
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C20H19N5O
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1
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| 1 |
Ki = 146 nM
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CP0423262
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3-benzyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
Show/Hide
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C17H14N6
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1
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| 1 |
Ki = 147 nM
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CP0414843
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4-(furan-2-yl)-11-methyl-N-(4-phenylbutan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H21N7O
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1
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| 1 |
Ki = 147 nM
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CP0452832
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5-[3-(3-methoxyphenyl)propyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C21H21N5O
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1
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| 1 |
Ki = 147 nM
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CP0402922
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2-[7-amino-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-2-yl]phenol
Show/Hide
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C16H13N5O2
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1
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| 1 |
Ki = 147 nM
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CP0428651
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1-[4-(furan-2-yl)-11-(2-phenylethyl)-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C27H23N7O3
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1
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| 1 |
Ki = 148 nM
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CP0412426
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benzyl 4-[2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetyl]piperazine-1-carboxylate
Show/Hide
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C32H37N5O6
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1
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| 1 |
Ki = 151.36 nM
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CP0439717
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8-(4-(4-benzylpiperazin-1-ylsulfonyl)phenyl)-1-ethyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C24H26N6O4S
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1
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| 1 |
Ki = 152 nM
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CP0490036
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5-[3-(2-methoxyphenyl)propyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C21H21N5O
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1
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| 1 |
Ki = 153 nM
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CP0415545
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[(2S)-1-[2-(3-bromoanilino)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]pyrrolidin-2-yl]methanol
Show/Hide
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C16H16BrN5OS
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1
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| 1 |
Ki = 153 nM
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CP0396875
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5-[(2-fluorophenyl)methyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C18H14FN5
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1
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| 1 |
Ki = 154 nM
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CP0412429
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6-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H26ClN5O4
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1
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| 1 |
Ki = 154.88 nM
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CP0513686
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phenyl 4-[2-[4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetyl]piperazine-1-carboxylate
Show/Hide
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C31H35N5O6
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1
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| 1 |
Ki = 154.88 nM
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CP0381325
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3-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]propan-1-ol
Show/Hide
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C14H15N7O2
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1
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| 1 |
Ki = 155 nM
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CP0405377
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2-Furan-2-yl-8-methyl-9-(4-methyl-piperazin-1-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine; dihydrochloride
Show/Hide
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C16H19N9O
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1
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| 1 |
Ki = 156 nM
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CP0410255
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10-benzyl-3-furan-2-yl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
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C20H14N4O2
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1
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| 1 |
Ki = 156 nM
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CP0464673
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2-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]ethanol
Show/Hide
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C13H13N7O2
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1
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| 1 |
Ki = 157 nM
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CP0378001
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(2-chloropurin-9-yl)-3,4-dihydroxytetrahydrothiphene-2-carboxylic acid methyl amide
Show/Hide
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C11H13ClN6O3S
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1
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| 1 |
Ki = 158 nM
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CP0418537
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4-benzylureido-1,2-dihydro-2-phenyl-1,2,4-triazolo[4,3-a]quinoxalin-1-one
Show/Hide
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C23H18N6O2
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1
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| 1 |
Ki = 158.3 nM
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CP0373450
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6-[4-[1-(3,4-dihydro-1H-isoquinolin-2-yl)-1-oxopropan-2-yl]oxyphenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H34N4O4
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1
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| 1 |
Ki = 158.49 nM
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CP0444684
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8-[4-[4-[(3-fluoro-5-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H29FN6O5S
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1
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| 1 |
Ki = 160 nM
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CP0431496
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3-Allyl-1-benzyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
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C19H16N4O2
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1
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| 1 |
Ki = 161 nM
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CP0498543
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8-(4-(4-(3-Chlorobenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H27ClN6O4S
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1
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| 1 |
Ki = 161 nM
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CP0419069
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N-(3-benzyl-5-phenyltriazolo[4,5-d]pyrimidin-7-yl)furan-3-carboxamide
Show/Hide
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C22H16N6O2
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1
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| 1 |
Ki = 161 nM
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CP0492834
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9-(5'-Cyclopropylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-methyladenine
Show/Hide
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C14H18N6O3S
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1
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| 1 |
Ki = 161 nM
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CP0442565
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8-[4-(benzylamidosulfonyl)phenyl]-1-propylxanthine
Show/Hide
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C21H21N5O4S
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1
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| 1 |
Ki = 162 nM
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CP0432110
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6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H35N5O4
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1
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| 1 |
Ki = 162.18 nM
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CP0529338
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3S)-3-hydroxy-3-phenylprop-1-ynyl]-6-(methylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H21N5O5
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1
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| 1 |
Ki = 163 nM
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CP0381330
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4-(furan-2-yl)-11-methyl-N-pentyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki = 168 nM
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CP0420805
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8-[4-[4-[4-(2-hydroxyethoxy)phenyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O6S
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1
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| 1 |
Ki = 168 nM
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CP0477181
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N-[2-(3,4-dimethoxyphenyl)ethyl]-2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C21H22N6O4
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1
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| 1 |
Ki = 169 nM
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CP0930443
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4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)butyl-ammonium chloride
Show/Hide
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C15H19ClN8O
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1
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| 1 |
Ki = 169 nM
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CP0412433
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6-[4-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H29N5O5
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1
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| 1 |
Ki = 169.82 nM
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CP0468149
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7-N-benzyl-2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C16H15N7O
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1
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| 1 |
Ki = 173 nM
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CP0373194
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1,3-dimethyl-6-[4-[2-methyl-1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]oxyphenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H31N5O4
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1
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| 1 |
Ki = 173.78 nM
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CP0405398
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6-[4-[2-oxo-2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C31H34F3N5O4
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1
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| 1 |
Ki = 173.78 nM
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CP0473049
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8-amino-6-[4-(2-morpholin-4-ylethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C23H24N6O3
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1
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| 1 |
Ki = 174 nM
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CP0116395
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1-(8-Allyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C21H18N8O3
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1
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| 1 |
Ki = 176 nM
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CP0435934
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2,6-diphenyl-8-ethyl-1-deazapurine
Show/Hide
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C20H17N3
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1
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| 1 |
Ki = 177 nM
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CP0414838
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4-(furan-2-yl)-N-[(4-methoxyphenyl)methyl]-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O2
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1
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| 1 |
Ki = 177 nM
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CP0385866
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5-N,7-N-dicyclohexyl-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C20H27N7O
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1
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| 1 |
Ki = 177 nM
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CP0536617
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C19H17N7O2S
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1
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| 1 |
Ki = 179 nM
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CP0222481
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1-(3-Chloro-phenyl)-3-(8-ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
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C19H15ClN8O2
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1
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| 1 |
Ki = 180 nM
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CP0401452
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N-(2-benzyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
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C25H19N5O
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1
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| 1 |
Ki = 180.6 nM
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CP0871533
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8-(Furan-2-yl)-N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine
Show/Hide
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C21H23N5O
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1
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| 1 |
Ki = 181 nM
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CP0373291
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6-[4-[2-[4-(5-chloro-1,3-benzothiazol-2-yl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H25ClN6O4S
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1
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| 1 |
Ki = 181.97 nM
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CP0396865
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1-cyclohexyl-3-[8-(1-ethoxyethenyl)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl]urea
Show/Hide
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C20H24N6O3
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1
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| 1 |
Ki = 183 nM
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CP0396540
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4-(furan-2-yl)-N-methoxy-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C12H11N7O2
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1
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| 1 |
Ki = 185 nM
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CP0494517
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ethyl 2-(furan-2-yl)-5-[(4-phenylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C25H21N5O3
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1
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| 1 |
Ki = 187 nM
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CP0418540
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N-(1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)pyridine-4-carboxamide
Show/Hide
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C21H14N6O2
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1
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| 1 |
Ki = 188 nM
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CP0360671
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2,6-diphenyl-8-isobutyl-1-deazapurine
Show/Hide
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C22H21N3
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1
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| 1 |
Ki = 189 nM
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CP0424438
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8-[4-[4-[(3-methylphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O4S
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1
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| 1 |
Ki = 189 nM
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CP0432647
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5,7-diphenyl-3H-imidazo[4,5-b]pyridin-2-ol
Show/Hide
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C18H13N3O
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1
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| 1 |
Ki = 192 nM
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CP0396621
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N-(4-phenyl-5-pyridin-2-yl-1,3-thiazol-2-yl)furan-2-carboxamide
Show/Hide
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C19H13N3O2S
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1
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| 1 |
Ki = 193 nM
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CP0251352
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2,6-diphenyl-8-cyclohexyl-1-deazapurine
Show/Hide
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C24H23N3
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1
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| 1 |
Ki = 194 nM
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CP0400894
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N-[2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C16H13N7O2
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1
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| 1 |
Ki = 194 nM
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CP0477180
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(4-methoxyphenyl)methyl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H17N5O4
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1
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| 1 |
Ki = 194 nM
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CP0382853
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5-(furan-2-yl)-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C15H11N5O
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1
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| 1 |
Ki = 195 nM
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CP0943820
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[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)propyl]carbamic acid tert-butyl ester
Show/Hide
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C19H24N8O3
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1
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| 1 |
Ki = 195 nM
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CP0394227
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(2R,3R,4S,5R)-2-[2-hex-1-ynyl-6-(propan-2-ylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C19H27N5O4
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1
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| 1 |
Ki = 196 nM
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CP0504260
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2-(Phenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C20H17N7
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1
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| 1 |
Ki = 196 nM
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CP0394641
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benzhydryl 2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C24H19N5O3
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1
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| 1 |
Ki = 197 nM
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CP0490055
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8-[4-[4-(3-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H28N6O5S
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1
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| 1 |
Ki = 197 nM
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CP0530029
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8-amino-6-[4-(2-hydroxy-3-morpholin-4-ylpropoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C24H26N6O4
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1
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| 1 |
Ki = 197 nM
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CP0047370
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1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(3-phenyl-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
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C26H21ClN8O2
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1
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| 1 |
Ki = 200 nM
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CP0102094
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(2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C17H17ClIN5O4
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1
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| 1 |
Ki = 200 nM
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CP0395753
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1-[4-(furan-2-yl)-11-propyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C22H21N7O3
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1
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| 1 |
Ki = 200 nM
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CP0424434
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[(2S)-1-(2-anilino-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)pyrrolidin-2-yl]methanol
Show/Hide
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C16H17N5OS
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1
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| 1 |
Ki = 200 nM
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CP0494051
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2-(furan-2-yl)-7-phenyl-1,3-benzoxazol-5-amine
Show/Hide
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C17H12N2O2
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1
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| 1 |
Ki = 202 nM
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CP0551160
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2-amino-7-(3-piperidin-1-ylpropoxy)-4-[4-(3-piperidin-1-ylpropoxy)phenyl]indeno[1,2-d]pyrimidin-5-one
Show/Hide
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C33H41N5O3
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1
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| 1 |
Ki = 203 nM
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CP0425280
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8-[4-[4-(2-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25ClN6O4S
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1
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| 1 |
Ki = 204 nM
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CP0381299
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2-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]butan-1-ol
Show/Hide
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C15H17N7O2
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1
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| 1 |
Ki = 207 nM
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CP0474846
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N-(3-oxo-4-phenyl-2,4,5,8,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),5,7,10,12-pentaen-7-yl)-2-phenylacetamide
Show/Hide
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C22H16N6O2
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1
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| 1 |
Ki = 208 nM
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CP0497680
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4-(cyclopentylamino)-2-phenylpyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-1(2H)-one
Show/Hide
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C19H18N6O
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1
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| 1 |
Ki = 208 nM
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CP0395750
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1-[11-(furan-2-yl)-4-propyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H20N8O3
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1
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| 1 |
Ki = 208 nM
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CP0388113
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N-ethyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C13H13N7O
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1
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| 1 |
Ki = 208 nM
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CP0474146
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8-[4-[4-[(4-azidophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H27N9O4S
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1
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| 1 |
Ki = 208 nM
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CP0396871
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ethyl 2-(furan-2-yl)-5-[[4-(trifluoromethyl)phenyl]methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H16F3N5O3
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1
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| 1 |
Ki = 209 nM
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CP0456019
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ethyl 2-(furan-2-yl)-5-(methoxyamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C13H13N5O4
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1
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| 1 |
Ki = 210 nM
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CP0536610
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N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-2-piperidin-1-ylacetamide
Show/Hide
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C22H21N3O4
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1
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| 1 |
Ki = 210 nM
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CP0381963
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4-(cyclohexylamino)-2-phenylpyrido[2,3-e][1,2,4]triazolo[4,3-a]pyrazin-1(2H)-one
Show/Hide
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C20H20N6O
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1
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| 1 |
Ki = 211 nM
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CP0558435
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5-N-[(3-methoxyphenyl)methyl]-2-methyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C14H15N5OS
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1
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| 1 |
Ki = 212 nM
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CP0520036
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9-ethyl-8-phenylpurin-6-amine
Show/Hide
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C13H13N5
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1
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| 1 |
Ki = 212 nM
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CP0463566
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5-[(2-methoxyphenyl)methyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C19H17N5O
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1
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| 1 |
Ki = 213 nM
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CP0463480
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ethyl 5-(2-ethylhexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H27N5O3
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1
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| 1 |
Ki = 215 nM
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CP0408871
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2-pyrazin-2-yl-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C14H11N7S2
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1
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| 1 |
Ki = 219 nM
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CP0405220
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2-amino-4-(4-ethoxyphenyl)-6-(1H-imidazol-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
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C19H16N6OS
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1
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| 1 |
Ki = 221 nM
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CP0427817
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1-[11-(furan-2-yl)-4-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C19H16N8O3
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1
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| 1 |
Ki = 222 nM
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CP0118650
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(2S,3S,4R,5R)-5-(2-chloro-6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrothiophene-2-carboxamide
Show/Hide
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C18H18ClIN6O3S
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1
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| 1 |
Ki = 223 nM
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CP0433858
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6-[4-[2-[4-(2-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1-methyl-3-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H30ClN5O4
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1
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| 1 |
Ki = 223.87 nM
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CP0383020
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2-amino-4-(furan-2-yl)-6-phenacylsulfanylpyridine-3,5-dicarbonitrile
Show/Hide
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C19H12N4O2S
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1
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| 1 |
Ki = 224 nM
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CP0383480
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N-[6-phenyl-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-4-yl]benzamide
Show/Hide
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C26H21N5O
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1
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| 1 |
Ki = 227 nM
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CP0432563
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2-m-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine
Show/Hide
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C17H14N4
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1
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| 1 |
Ki = 228 nM
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CP0360672
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2,6-diphenyl-8-isopropyl-1-deazapurine
Show/Hide
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C21H19N3
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1
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| 1 |
Ki = 230 nM
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CP0437655
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8-amino-2-phenyl-6-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C23H24N6O2
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1
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| 1 |
Ki = 230 nM
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CP0085153
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9-cyclobutyl-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C16H19N5O2
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1
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| 1 |
Ki = 231 nM
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CP0456466
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8-amino-2-(2-hydroxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H13N5O2
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1
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| 1 |
Ki = 232 nM
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CP0391388
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N-cyclohexyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C17H19N7O
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1
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| 1 |
Ki = 233 nM
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CP0944003
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N'-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)hydrazinium chloride
Show/Hide
|
C11H11ClN8O
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1
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| 1 |
Ki = 233 nM
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CP0487927
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ethyl 5-(cycloheptylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C19H23N5O3
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1
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| 1 |
Ki = 235 nM
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CP0385356
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7-N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-5-N-methyl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C16H14FN7O
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1
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| 1 |
Ki = 235 nM
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CP0427209
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1-Ethyl-8-(4-(4-(4-methoxybenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H28N6O5S
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1
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| 1 |
Ki = 236 nM
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CP0373455
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6-[4-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]oxyphenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C31H37N5O4
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1
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| 1 |
Ki = 239.88 nM
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CP0433834
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1,3-bis(cyclopropylmethyl)-6-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C31H32N4O4
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1
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| 1 |
Ki = 239.88 nM
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CP0452649
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2-[7-amino-5-(3-phenylpropyl)pyrazolo[4,3-d]pyrimidin-2-yl]phenol
Show/Hide
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C20H19N5O
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1
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| 1 |
Ki = 240 nM
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CP0482644
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8-[4-[4-[[4-(2-hydroxyethoxy)phenyl]methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C27H32N6O6S
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1
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| 1 |
Ki = 241 nM
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CP0453968
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1-Benzyl-3-cyclopropylmethyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
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C20H18N4O2
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1
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| 1 |
Ki = 242 nM
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CP0391386
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N-[(2S)-butan-2-yl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C15H17N7O
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1
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| 1 |
Ki = 244 nM
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CP0381289
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4-(furan-2-yl)-11-methyl-N-[[4-(trifluoromethyl)phenyl]methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H14F3N7O
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1
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| 1 |
Ki = 245 nM
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CP0445855
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N-(3-bromophenyl)-7-pyrrolidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
|
C15H14BrN5S
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1
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| 1 |
Ki = 245 nM
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CP0420865
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8-[4-[4-[(3-fluoro-4-methoxyphenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H29FN6O5S
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1
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| 1 |
Ki = 245 nM
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CP0382856
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5-methyl-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C12H11N5
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1
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| 1 |
Ki = 246 nM
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CP0311586
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2,6-diphenyl-8-(1-ethylpropyl)-1-deazapurine
Show/Hide
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C23H23N3
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1
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| 1 |
Ki = 247 nM
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CP0167686
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1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
Show/Hide
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C17H11ClN8O2
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1
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| 1 |
Ki = 248 nM
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CP0857913
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(R,S)-(+,)-sec-Butyl-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e]-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)amine
Show/Hide
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C15H17N7O
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1
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| 1 |
Ki = 248 nM
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CP0537190
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5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-amine
Show/Hide
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C12H10N4S
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1
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| 1 |
Ki = 248 nM
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CP0421266
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(2R,3S,4S,5R)-6-amino-5-ethylcarboxyamide-2-(3''-indolyl)-ethyloxy)-purin-9-yl)-tetrahydrofuran
Show/Hide
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C22H25N7O5
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1
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| 1 |
Ki = 250 nM
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CP0437652
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8-amino-6-[4-(2-hydroxyethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C19H17N5O3
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1
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| 1 |
Ki = 250 nM
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CP0388106
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]butan-1-ol
Show/Hide
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C15H17N7O2
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1
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| 1 |
Ki = 251 nM
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CP0425055
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2-(3''(7''-bromo-indolyl)ethyloxy)adenosine
Show/Hide
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C20H21BrN6O5
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1
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| 1 |
Ki = 252 nM
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CP0172527
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9-benzyl-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C19H19N5O2
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1
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| 1 |
Ki = 253 nM
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CP0870386
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3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)propyl-ammonium chloride
Show/Hide
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C14H17ClN8O
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1
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| 1 |
Ki = 253 nM
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CP0388721
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6-(4-(2-(4-benzylpiperazin-1-yl)-2-oxoethoxy)phenyl)-1,3-dipropyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione
Show/Hide
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C31H37N5O4
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1
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| 1 |
Ki = 257.04 nM
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CP0439433
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1-(4-methoxy-phenyl)-3-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-urea
Show/Hide
|
C23H18N6O3
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1
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| 1 |
Ki = 262.1 nM
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CP0373199
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6-[4-[2-methyl-1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]oxyphenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C32H39N5O4
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1
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| 1 |
Ki = 263.03 nM
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CP0429539
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6-bromo-2-(furan-2-yl)imidazo[1,2-a]pyrazin-8-amine
Show/Hide
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C10H7BrN4O
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1
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| 1 |
Ki = 265 nM
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CP0394490
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(2R,3R,4S,5R)-2-[6-(ethylamino)-2-hex-1-ynylpurin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C18H25N5O4
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1
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| 1 |
Ki = 267 nM
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CP0527599
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2-(hex-1-ynyl)-N6-methoxyadenosine
Show/Hide
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C17H23N5O5
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1
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| 1 |
Ki = 267 nM
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CP0435342
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8-(3-chlorophenyl)-N-cyclopentyl-9-methylpurin-6-amine
Show/Hide
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C17H18ClN5
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1
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| 1 |
Ki = 267 nM
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CP0409549
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6-[4-[1-[4-(4-bromophenyl)piperazin-1-yl]-1-oxopropan-2-yl]oxyphenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H28BrN5O4
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1
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| 1 |
Ki = 269.15 nM
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CP0377685
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8-(4-(4-Phenethylpiperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C26H30N6O4S
|
1
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| 1 |
Ki = 271 nM
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CP0396547
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N-[(2R)-butan-2-yl]-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C15H17N7O
|
1
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| 1 |
Ki = 272 nM
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CP0849861
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2-Hydroxymethyl-5-[2-(3-hydroxy-3-phenyl-prop-1-ynyl)-6-methylamino-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
|
C20H21N5O5
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1
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| 1 |
Ki = 273 nM
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CP0860933
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6-guanidino-2-(3''-indolylethyloxy)adenosine
Show/Hide
|
C21H24N8O5
|
1
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| 1 |
Ki = 277 nM
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CP0377682
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8-(4-(4-(3-Fluorobenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H27FN6O4S
|
1
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| 1 |
Ki = 278 nM
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CP0488587
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N-cyclooctyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H23N7O
|
1
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| 1 |
Ki = 279 nM
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CP0525976
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ethyl 4-[4-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperazin-1-yl]benzoate
Show/Hide
|
C22H22N6O3S
|
1
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| 1 |
Ki = 279 nM
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CP0148609
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9-(3-bromophenyl)-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C18H16BrN5O2
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1
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| 1 |
Ki = 284 nM
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CP0853604
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8-Bromo-N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C17H21BrN6
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1
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| 1 |
Ki = 284 nM
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CP0380868
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ethyl 2-(furan-2-yl)-5-(2-methoxyethylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C15H17N5O4
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1
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| 1 |
Ki = 292 nM
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CP0882701
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8-(4-(3-methyl-4-phenylpiperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C25H28N6O4S
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1
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| 1 |
Ki = 293 nM
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CP0339232
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4-[2-[[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]amino]ethyl]benzenesulfonamide
Show/Hide
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C17H16N6O3S2
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1
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| 1 |
Ki = 295 nM
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CP0371939
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2-amino-N-(3-benzyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)benzamide
Show/Hide
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C24H19N7O
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1
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| 1 |
Ki = 297 nM
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CP0385413
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8-Bromo-9-propyl-9H-adenine
Show/Hide
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C8H10BrN5
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1
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| 1 |
Ki = 300 nM
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CP0385444
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2-benzyl-5-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C18H15N5
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1
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| 1 |
Ki = 300 nM
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CP0385871
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N-[2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C17H15N7O2
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1
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| 1 |
Ki = 300 nM
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CP0412431
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6-[4-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H27FN4O5
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1
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| 1 |
Ki = 302 nM
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CP0393016
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N-cyclobutyl-9-methyl-8-phenylpurin-6-amine
Show/Hide
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C16H17N5
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1
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| 1 |
Ki = 303 nM
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CP0503490
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N-(3-benzyl-5-phenyltriazolo[4,5-d]pyrimidin-7-yl)thiophene-2-carboxamide
Show/Hide
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C22H16N6OS
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1
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| 1 |
Ki = 305 nM
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CP0388100
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1-Propyl-8-(4-(4-(3-trifluoromethylbenzyl)piperazine-1-sulfonyl)phenyl)-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H27F3N6O4S
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1
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| 1 |
Ki = 306 nM
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CP0381033
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6-cyclooctyl-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
Show/Hide
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C17H25N5O2
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1
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| 1 |
Ki = 306 nM
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CP0523458
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N-cyclohexyl-9-ethyl-8-phenylpurin-6-amine
Show/Hide
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C19H23N5
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1
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| 1 |
Ki = 307 nM
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CP0456121
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2-[6-amino-3,5-dicyano-4-[4-(2-methylpropoxy)phenyl]pyridin-2-yl]sulfanylacetamide
Show/Hide
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C19H19N5O2S
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1
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| 1 |
Ki = 307 nM
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CP0557261
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8-amino-2-(2-methoxyphenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C18H15N5O2
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1
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| 1 |
Ki = 309 nM
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CP0429540
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2,6-diphenylimidazo[1,2-a]pyrazin-8-amine
Show/Hide
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C18H14N4
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1
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| 1 |
Ki = 310 nM
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CP0058445
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9-cyclohexyl-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C18H23N5O2
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1
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| 1 |
Ki = 311 nM
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CP0415544
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[(2S)-1-[2-(4-methylanilino)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]pyrrolidin-2-yl]methanol
Show/Hide
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C17H19N5OS
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1
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| 1 |
Ki = 313 nM
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CP0478383
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2-methyl-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C11H11N5S2
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1
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| 1 |
Ki = 313 nM
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CP0947568
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[4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)butyl]carbamic acid tert-butyl ester
Show/Hide
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C20H26N8O3
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1
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| 1 |
Ki = 313 nM
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CP0383484
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3-chloro-N-(2-phenethyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
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C26H20ClN5O
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1
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| 1 |
Ki = 314 nM
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CP0424439
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8-[4-[4-[[4-[2-(2-methoxyethoxy)ethoxy]phenyl]methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C30H38N6O7S
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1
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| 1 |
Ki = 314 nM
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CP0902329
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2-{2-[2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamino)ethoxy]ethoxy}ethyl-ammonium chloride
Show/Hide
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C17H23ClN8O3
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1
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| 1 |
Ki = 314 nM
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CP0399717
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1-methyl-6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-3-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H31N5O4
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1
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| 1 |
Ki = 316.23 nM
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CP0058446
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1-methyl-3-prop-2-ynyl-9-(2-thiophen-2-ylethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C18H19N5O2S
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1
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| 1 |
Ki = 317 nM
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CP0409660
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2-benzyl-5-(furan-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C16H13N5O
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1
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| 1 |
Ki = 320 nM
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CP0149047
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9-[(3-methoxyphenyl)methyl]-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C20H21N5O3
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1
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| 1 |
Ki = 322 nM
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CP0420869
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8-[4-[4-(4-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-3-ethyl-1-propyl-7H-purine-2,6-dione
Show/Hide
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C26H29ClN6O4S
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1
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| 1 |
Ki = 322 nM
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CP0373201
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6-[4-[2-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H27ClN4O5
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1
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| 1 |
Ki = 323.59 nM
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CP0394407
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6-[4-[2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C25H24Cl2N6O4
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1
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| 1 |
Ki = 323.59 nM
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CP0409551
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3-methyl-6-[4-[2-oxo-2-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]ethoxy]phenyl]-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C29H30F3N5O4
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1
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| 1 |
Ki = 323.59 nM
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CP0510600
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6-[4-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H26FN5O4
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1
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| 1 |
Ki = 323.59 nM
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CP0435733
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]-6-(propan-2-ylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C22H25N5O5
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1
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| 1 |
Ki = 324 nM
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CP0493965
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N-(11-methyl-4-phenyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl)benzamide
Show/Hide
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C20H15N7O
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1
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| 1 |
Ki = 324 nM
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CP0382860
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2,5-diphenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C17H13N5
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1
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| 1 |
Ki = 325 nM
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CP0397160
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C21H19N7OS
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1
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| 1 |
Ki = 327 nM
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CP0388500
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8-(4-(4-(4-Methoxybenzyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O5S
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1
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| 1 |
Ki = 328 nM
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CP0403420
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2,5-diethyl-8-methyl-4,7-dihydro-1H-benzo[1,2-d:3,4-d':5,6-d'']-triimidazole
Show/Hide
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C14H16N6
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1
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| 1 |
Ki = 329 nM
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CP0443181
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2-p-Tolyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine
Show/Hide
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C17H14N4
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1
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| 1 |
Ki = 329 nM
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CP0420733
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[(2S)-1-[2-(3,4,5-trimethoxyanilino)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]pyrrolidin-2-yl]methanol
Show/Hide
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C19H23N5O4S
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1
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| 1 |
Ki = 330 nM
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CP0387534
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8-(4-(4-(4-chlorobenzyl)piperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C25H27ClN6O4S
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1
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| 1 |
Ki = 333 nM
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CP0424463
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7-morpholin-4-yl-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C15H15N5OS
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1
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| 1 |
Ki = 333 nM
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CP0435361
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N-cyclopentyl-9-ethyl-8-phenylpurin-6-amine
Show/Hide
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C18H21N5
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1
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| 1 |
Ki = 334 nM
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CP0258312
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N-[11-ethyl-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C20H17N7O2
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1
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| 1 |
Ki = 335 nM
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CP0491243
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N-cycloheptyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H21N7O
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1
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| 1 |
Ki = 336 nM
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CP0387249
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2-(furan-2-yl)-5-(methylamino)-N'-phenyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carbohydrazide
Show/Hide
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C17H15N7O2
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1
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| 1 |
Ki = 342 nM
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CP0871144
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6-guanidino-2-(3''-(1''-(p-toluenesulfonyl)indolyl)ethyloxy)adenosine
Show/Hide
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C28H30N8O7S
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1
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| 1 |
Ki = 344 nM
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CP0149072
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9-[2-(4-hydroxyphenyl)ethyl]-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C20H21N5O3
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1
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| 1 |
Ki = 346 nM
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CP0902330
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[5-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)pentyl]carbamic acid tert-butyl ester
Show/Hide
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C21H28N8O3
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1
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| 1 |
Ki = 346 nM
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CP0079479
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2-Furan-2-yl-8-(2,4,5-tribromo-benzyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C18H12Br3N7O
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1
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| 1 |
Ki = 348 nM
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CP0383231
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N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)furan-2-carboxamide
Show/Hide
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C21H14N2O3S
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1
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| 1 |
Ki = 348 nM
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CP0870387
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3-(2-{2-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamino)propoxy]ethoxy}ethoxy)propyl-ammonium chloride
Show/Hide
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C21H31ClN8O4
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1
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| 1 |
Ki = 348 nM
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CP0463447
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4-(cyclooctylmethyl)-2-cyclopenta-1,3-dien-1-yl-7-pent-1-en-2-yl-3aH-indene
Show/Hide
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C28H36
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1
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| 1 |
Ki = 351 nM
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CP0473544
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N-phenyl-7-pyrrolidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C15H15N5S
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1
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| 1 |
Ki = 351 nM
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CP0397420
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4-(furan-2-yl)-11-methyl-7-piperidin-1-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C16H17N7O
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1
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| 1 |
Ki = 352 nM
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CP0373290
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6-[4-[2-[4-(2-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H26ClN5O4
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1
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| 1 |
Ki = 354.81 nM
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CP0394406
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4-[4-[2-[4-(1,3-dimethyl-2,4-dioxo-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetyl]piperazin-1-yl]benzonitrile
Show/Hide
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C27H26N6O4
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1
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| 1 |
Ki = 354.81 nM
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CP0516384
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1,3-dimethyl-6-[4-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]oxyphenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H29N5O4
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1
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| 1 |
Ki = 354.81 nM
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CP0414910
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2-(4-Fluorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C13H10FN7
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1
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| 1 |
Ki = 355 nM
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CP0473050
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8-amino-6-[4-(2,3-dihydroxypropoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C20H19N5O4
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1
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| 1 |
Ki = 355 nM
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CP0446607
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4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)-N-methyl-N-(2-phenylethyl)benzenesulfonamide
Show/Hide
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C23H25N5O4S
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1
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| 1 |
Ki = 357 nM
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CP0510259
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(2R,3R,4S,5R)-2-(6-amino-2-ethoxy-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C12H17N5O5
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1
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| 1 |
Ki = 360 nM
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CP0402923
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5-(furan-2-yl)-2-(2-methoxyphenyl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C16H13N5O2
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1
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| 1 |
Ki = 362 nM
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CP0270772
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(2R,3R,4S,5R)-2-(6-amino-2-(phenylethynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
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C18H17N5O4
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1
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| 1 |
Ki = 363 nM
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CP0393023
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N-cyclobutyl-8-phenyl-9-propylpurin-6-amine
Show/Hide
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C18H21N5
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1
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| 1 |
Ki = 365 nM
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CP0058054
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N-(6-amino-1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)acetamide
Show/Hide
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C17H14N6O2
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1
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| 1 |
Ki = 367 nM
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CP0430116
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4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C12H11N7O
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1
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| 1 |
Ki = 368 nM
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CP0407957
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-fluoro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21FN6O5
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1
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| 1 |
Ki = 370 nM
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CP0425419
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2-(2''-indolylethyloxy)adenosine
Show/Hide
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C20H22N6O5
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1
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| 1 |
Ki = 373 nM
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CP0420532
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2,6-diphenyl-8-methyl-1-deazapurine
Show/Hide
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C19H15N3
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1
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| 1 |
Ki = 375 nM
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CP0434929
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ethyl 2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C19H24N6O5
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1
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| 1 |
Ki = 376 nM
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CP0393015
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N-cyclobutyl-9-ethyl-8-phenylpurin-6-amine
Show/Hide
|
C17H19N5
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1
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| 1 |
Ki = 379 nM
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CP0273529
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1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenylurea
Show/Hide
|
C18H14N8O2
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1
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| 1 |
Ki = 381 nM
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CP0393017
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9-methyl-8-phenylpurin-6-amine
Show/Hide
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C12H11N5
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1
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| 1 |
Ki = 381 nM
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CP0406245
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1-Benzyl-7-tert-butyl-3-propyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
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C23H26N4O2
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1
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| 1 |
Ki = 385 nM
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CP0411865
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ethyl 5-(benzhydrylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C25H21N5O3
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1
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| 1 |
Ki = 385 nM
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CP0432538
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2-(4-hydroxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H12N4O3
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1
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| 1 |
Ki = 387 nM
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CP0391353
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4-(furan-2-yl)-11-methyl-N-propan-2-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H15N7O
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1
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| 1 |
Ki = 389 nM
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CP0412423
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1,3-dimethyl-6-[4-[1-[4-(4-methylphenyl)piperazin-1-yl]-1-oxopropan-2-yl]oxyphenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H31N5O4
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1
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| 1 |
Ki = 389.05 nM
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CP0427746
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-chloro-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21ClN6O5
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1
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| 1 |
Ki = 390 nM
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CP0417367
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8-Bromo-9-(sec-butyl)-9H-adenine
Show/Hide
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C9H12BrN5
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1
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| 1 |
Ki = 390 nM
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CP0385010
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N-[2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]-2-phenylacetamide
Show/Hide
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C19H19N7O2
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1
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| 1 |
Ki = 393 nM
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CP0385874
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7-N-benzyl-2-(furan-2-yl)-5-N-propan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C18H19N7O
|
1
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| 1 |
Ki = 394 nM
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CP0433424
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N-[2-(4-methoxyphenyl)-1-oxo-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]pyridine-4-carboxamide
Show/Hide
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C22H16N6O3
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1
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| 1 |
Ki = 397 nM
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CP0468150
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7-N-cyclohexyl-2-(furan-2-yl)-5-N-propan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine
Show/Hide
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C17H23N7O
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1
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| 1 |
Ki = 397 nM
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CP0457530
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2-mercaptopyrimidine analogue, 5d
Show/Hide
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C11H17N3O2S
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1
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| 1 |
Ki = 398 nM
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CP0399706
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6-[4-[2-[4-(4-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H26ClN5O4
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1
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| 1 |
Ki = 398.11 nM
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CP0432108
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1,3-bis(2-methoxyethyl)-6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H35N5O6
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1
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| 1 |
Ki = 398.11 nM
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CP0513722
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6-[4-[2-[4-(4-methoxyphenyl)piperidin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H34N4O5
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1
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| 1 |
Ki = 398.11 nM
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CP0391657
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(2R,3R,4S,5R)-2-[6-(5-Chloro-2-methoxy-benzylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C18H20ClN5O5
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1
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| 1 |
Ki = 400 nM
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CP0017043
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(2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl]amino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide
Show/Hide
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C18H18ClIN6O4
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4
|
| 1 |
Ki = 401 nM
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| 2 |
Ki = 448 nM
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| 3 |
Ki = 5360 nM
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| 4 |
Ki = 5400 nM
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CP0448682
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8-amino-2-(4-nitrophenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C17H12N6O3
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1
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| 1 |
Ki = 402 nM
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CP0408874
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5-N-[2-(4-methoxyphenyl)ethyl]-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C20H19N5OS
|
1
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| 1 |
Ki = 403 nM
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CP0420822
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8-[4-[4-[(4-bromo-3-fluorophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H26BrFN6O4S
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1
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| 1 |
Ki = 403 nM
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CP0408870
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2-phenyl-5-N-(2-phenylethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C19H17N5S
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1
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| 1 |
Ki = 406 nM
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CP0397423
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4-(furan-2-yl)-N-(2-methoxyethyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H15N7O2
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1
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| 1 |
Ki = 407 nM
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CP0412432
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6-[4-[2-[4-(2-methoxyphenyl)piperidin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H34N4O5
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1
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| 1 |
Ki = 407.38 nM
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CP0419545
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2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C11H9N5
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1
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| 1 |
Ki = 410 nM
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CP0402921
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2-(7-amino-5-thiophen-2-ylpyrazolo[4,3-d]pyrimidin-2-yl)phenol
Show/Hide
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C15H11N5OS
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1
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| 1 |
Ki = 412 nM
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CP0498139
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(2R,3R,4S,5R)-2-(6-amino-2-((S)-3-phenylbutoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H25N5O5
|
1
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| 1 |
Ki = 413 nM
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CP0447253
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2-(4-aminophenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
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C17H13N5O2
|
1
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| 1 |
Ki = 415 nM
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CP0412436
|
1,3-dimethyl-6-[4-[2-oxo-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C24H25N7O4
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1
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| 1 |
Ki = 416.87 nM
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CP0445312
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9-(cyclopropylmethyl)-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C14H19N5O2
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1
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| 1 |
Ki = 417 nM
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CP0070215
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9-[(2-methoxyphenyl)methyl]-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C20H21N5O3
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1
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| 1 |
Ki = 417 nM
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CP0258311
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N-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C19H15N7O2
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1
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| 1 |
Ki = 423 nM
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CP0540684
|
2-amino-4-[4-(cyclopropylmethoxy)phenyl]-6-(pyridin-3-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
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C23H19N5OS
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1
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| 1 |
Ki = 424 nM
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CP0373203
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6-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C25H24N4O4
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1
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| 1 |
Ki = 426.58 nM
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CP0517713
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N-[2-(furan-2-yl)-5-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]furan-2-carboxamide
Show/Hide
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C20H12N4O3S
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1
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| 1 |
Ki = 428 nM
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CP0378251
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1N-methyl-4-[2-chloro-6-(5-iodo-2-methoxybenzylamino)-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C21H22ClIN6O4
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1
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| 1 |
Ki = 430 nM
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CP0536612
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7-(4-fluorophenyl)-2-(furan-2-yl)-1,3-benzoxazol-5-amine
Show/Hide
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C17H11FN2O2
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1
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| 1 |
Ki = 438 nM
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CP0468908
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4-(furan-2-yl)-N-heptan-2-yl-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H23N7O
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1
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| 1 |
Ki = 446 nM
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CP0394229
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-hydroxy-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H22N6O6
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1
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| 1 |
Ki = 450 nM
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CP0393020
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N-cyclopentyl-9-methyl-8-(3-methylphenyl)purin-6-amine
Show/Hide
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C18H21N5
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1
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| 1 |
Ki = 450 nM
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CP0439459
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1-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-3-phenyl-urea
Show/Hide
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C22H16N6O2
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1
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| 1 |
Ki = 460.2 nM
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CP0434147
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2-(benzylamino)-4-(furan-2-yl)-6-(2-hydroxyethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
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C20H16N4O2S
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1
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| 1 |
Ki = 461 nM
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CP0049200
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(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C15H21N5O4
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3
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| 1 |
Ki = 462 nM
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| 2 |
Ki = 790 nM
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| 3 |
Ki = 794 nM
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CP0451551
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[(2S)-1-[2-(4-chloroanilino)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]pyrrolidin-2-yl]methanol
Show/Hide
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C16H16ClN5OS
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1
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| 1 |
Ki = 466 nM
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CP0373466
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6-[4-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H30FN5O4
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1
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| 1 |
Ki = 467.74 nM
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CP0118648
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(2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyl-tetrahydrothiophene-2-carboxamide
Show/Hide
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C18H19IN6O3S
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1
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| 1 |
Ki = 475 nM
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CP0373461
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6-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H30ClN5O4
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1
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| 1 |
Ki = 478.63 nM
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CP0442231
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1N-methyl-4-[2-chloro-6-(2-chloro-5-iodobenzylamino)-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C20H19Cl2IN6O3
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1
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| 1 |
Ki = 480 nM
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CP0561740
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N-[7-amino-2-(furan-2-yl)-1,3-benzoxazol-5-yl]-2-piperidin-1-ylacetamide
Show/Hide
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C18H20N4O3
|
1
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| 1 |
Ki = 480 nM
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CP0234416
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8-(4-(4-benzylpiperazin-1-ylsulfonyl)phenyl)-1-propyl-1H-purine-2,6(3H,7H)-dione
Show/Hide
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C25H28N6O4S
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1
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| 1 |
Ki = 484 nM
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CP0458576
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8-amino-6-methyl-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C12H11N5O
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1
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| 1 |
Ki = 485 nM
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CP0378551
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2-(3-methoxyphenyl)-2H-pyrazolo[3,4-c]quinolin-4-amine
Show/Hide
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C17H14N4O
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1
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| 1 |
Ki = 486 nM
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CP0340023
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-4-sulfamoylbenzamide
Show/Hide
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C22H23N7O4S2
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1
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| 1 |
Ki = 488 nM
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CP0547381
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetamide
Show/Hide
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C24H23N7O5S2
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1
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| 1 |
Ki = 488 nM
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CP0478877
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8-phenyl-9-propylpurin-6-amine
Show/Hide
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C14H15N5
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1
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| 1 |
Ki = 492 nM
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CP0445435
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4-amino-2-(4-chloro-phenyl)-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-1-one
Show/Hide
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C15H10ClN5O
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1
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| 1 |
Ki = 493.3 nM
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CP0520046
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N-cyclopentyl-9-methyl-8-phenylpurin-6-amine
Show/Hide
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C17H19N5
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1
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| 1 |
Ki = 498 nM
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CP0496056
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2-phenylpropoxyadenosine
Show/Hide
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C19H23N5O5
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1
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| 1 |
Ki = 500 nM
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CP0441293
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
|
C20H17N7O3
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1
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| 1 |
Ki = 500 nM
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CP0394566
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-bromo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21BrN6O5
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1
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| 1 |
Ki = 502 nM
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CP0047383
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1-(8-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-nitro-phenyl)-urea
Show/Hide
|
C21H19N9O4
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1
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| 1 |
Ki = 503 nM
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CP0911667
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8-Bromo-N-phenethyl-9-propyl-9H-purin-6-amine
Show/Hide
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C16H18BrN5
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1
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| 1 |
Ki = 503 nM
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CP0176304
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9-[2-(4-methoxyphenyl)ethyl]-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C21H23N5O3
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1
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| 1 |
Ki = 508 nM
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CP0146806
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(2R,3R,4S,5R)-2-[6-(2,2-Diphenyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
|
C24H25N5O4
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1
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| 1 |
Ki = 510 nM
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CP0108301
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9-(cyclohexylmethyl)-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C19H25N5O2
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1
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| 1 |
Ki = 510 nM
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CP0399190
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N-(2-ethylhexyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H25N7O
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1
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| 1 |
Ki = 512 nM
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CP0382859
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2-(2-methoxyphenyl)-5-(5-methylfuran-2-yl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
|
C17H15N5O2
|
1
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| 1 |
Ki = 518 nM
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CP0383506
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(2R,3R,4S,5R)-2-(6-amino-2-(4-phenylbutoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C20H25N5O5
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1
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| 1 |
Ki = 519 nM
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CP0045157
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1-(2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
|
C18H14N8O3
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1
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| 1 |
Ki = 520 nM
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CP0429541
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2-(furan-2-yl)-6-phenylimidazo[1,2-a]pyrazin-8-amine
Show/Hide
|
C16H12N4O
|
1
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| 1 |
Ki = 520 nM
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CP0452831
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3-[(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)methyl]phenol
Show/Hide
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C18H15N5O
|
1
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| 1 |
Ki = 521 nM
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CP0398648
|
1-(1-benzylpiperidin-4-yl)-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
|
C24H25N9O2
|
1
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| 1 |
Ki = 526 nM
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CP0412437
|
N-cyclohexyl-9-methyl-8-phenylpurin-6-amine
Show/Hide
|
C18H21N5
|
1
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| 1 |
Ki = 527 nM
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CP0456686
|
5-N-benzyl-2-methyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C13H13N5S
|
1
|
| 1 |
Ki = 532 nM
|
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|
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CP0422779
|
4-[6-(cyclopentylamino)-9-methylpurin-8-yl]phenol
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
Ki = 532 nM
|
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CP0116394
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1-(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxy-phenyl)-urea
Show/Hide
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C22H22N8O3
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1
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| 1 |
Ki = 545 nM
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CP0398710
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1,3-dibutyl-9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C30H46N6O3
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1
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| 1 |
Ki = 546 nM
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CP0853599
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8-(Furan-2-yl)-N-phenethyl-9-propyl-9H-purin-6-amine
Show/Hide
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C20H21N5O
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1
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| 1 |
Ki = 547 nM
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CP0380974
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N-[4-phenyl-5-(pyridine-3-carbonyl)-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C20H13N3O3S
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1
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| 1 |
Ki = 552 nM
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CP0385368
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N-benzyl-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
Show/Hide
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C21H16N6O2
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1
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| 1 |
Ki = 560 nM
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CP0405046
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2-(1H-1,3-benzodiazol-2-yl)quinoxaline
Show/Hide
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C15H10N4
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1
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| 1 |
Ki = 561 nM
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CP0397159
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
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C22H21N7OS
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1
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| 1 |
Ki = 562 nM
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CP0433842
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3-methyl-6-[4-[2-methyl-1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]oxyphenyl]-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C30H35N5O4
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1
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| 1 |
Ki = 562.34 nM
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CP0473649
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N-[4-(4-fluorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C28H22FN7O
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1
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| 1 |
Ki = 571 nM
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CP0529145
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2-[4-(4-acetamidophenyl)-6-amino-3,5-dicyanopyridin-2-yl]sulfanylacetamide
Show/Hide
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C17H14N6O2S
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1
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| 1 |
Ki = 572 nM
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CP0437752
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N-(3-benzyl-5-phenyltriazolo[4,5-d]pyrimidin-7-yl)furan-2-carboxamide
Show/Hide
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C22H16N6O2
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1
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| 1 |
Ki = 573 nM
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CP0409690
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(2R,3R,4S,5R)-2-(6-amino-2-(2-cyclohexylethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C18H27N5O5
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1
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| 1 |
Ki = 579 nM
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CP0463666
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3-[[6-amino-3,5-dicyano-4-(furan-2-yl)pyridin-2-yl]sulfanylmethyl]benzoic acid
Show/Hide
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C19H12N4O3S
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1
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| 1 |
Ki = 581 nM
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CP0431290
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1-Benzyl-3-ethyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
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C18H16N4O2
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1
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| 1 |
Ki = 584 nM
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CP0399749
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6-[4-[2-oxo-2-(4-phenylpiperidin-1-yl)ethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C31H36N4O4
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1
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| 1 |
Ki = 588.84 nM
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CP0380000
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4-(furan-2-yl)-11-methyl-N-[(4-phenylphenyl)methyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C24H19N7O
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1
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| 1 |
Ki = 593 nM
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CP0380873
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5-(cyclopropylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C13H11N5O3
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1
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| 1 |
Ki = 596 nM
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CP0396548
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2-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]propane-1,3-diol
Show/Hide
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C14H15N7O3
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1
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| 1 |
Ki = 597 nM
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CP0383302
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9-Ethyl-8-phenylethynyl-9H-purin-6-ylamine
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C15H13N5
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1
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| 1 |
Ki = 600 nM
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CP0519953
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2-methyl-5-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C12H11N5S
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1
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| 1 |
Ki = 608 nM
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CP0300598
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1,3-dimethyl-9-(4-methylcyclohexyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C17H25N5O2
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1
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| 1 |
Ki = 610 nM
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CP0210714
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1-(8-Ethyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-nitro-phenyl)-urea
Show/Hide
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C19H15N9O4
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1
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| 1 |
Ki = 614 nM
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CP0390257
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2-phenyl-N-[4-phenyl-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]acetamide
Show/Hide
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C28H23N7O
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1
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| 1 |
Ki = 614 nM
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CP0394405
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6-[4-[2-[4-(4-hydroxyphenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H27N5O5
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1
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| 1 |
Ki = 616.6 nM
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CP0241358
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(2S,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin-3-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide
Show/Hide
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C20H20N6O4
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1
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| 1 |
Ki = 620 nM
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CP0381882
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2-(6-amino-8-bromo-9H-purin-9-yl)ethanol
Show/Hide
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C7H8BrN5O
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1
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| 1 |
Ki = 620 nM
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CP0882742
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[2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)ethyl]carbamic acid tert-butyl ester
Show/Hide
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C18H22N8O3
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1
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| 1 |
Ki = 624 nM
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CP0495632
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1-(3-chloro-phenyl)-3-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-urea
Show/Hide
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C22H15ClN6O2
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1
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| 1 |
Ki = 625 nM
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CP0401400
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1-[11-(furan-2-yl)-3-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N8O3
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1
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| 1 |
Ki = 626 nM
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CP0070214
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1-methyl-3-prop-2-ynyl-9-(thiophen-2-ylmethyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C17H17N5O2S
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1
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| 1 |
Ki = 626 nM
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CP0511213
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6-amino-1,2-dihydro-2-phenyl-4-diphenylacetamido-1,2,4-triazolo[4,3-a]quinoxalin-1-one
Show/Hide
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C29H22N6O2
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1
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| 1 |
Ki = 627 nM
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CP0425048
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(2S,3S,4R,5R)-N-ethyl-5-(6-guanidino-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
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C13H18N8O4
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1
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| 1 |
Ki = 628 nM
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CP0137800
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9-(1-benzylpiperidin-4-yl)-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C24H28N6O2
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1
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| 1 |
Ki = 628 nM
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CP0394403
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6-[4-[2-[4-(6-chloro-1,3-benzothiazol-2-yl)piperazin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C29H29ClN6O4S
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1
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| 1 |
Ki = 630.96 nM
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CP0382272
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1-deoxy-1-{2-chloro-6-[N'-(2-thiophen-2-yl-acetyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C18H20ClN7O5S
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1
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| 1 |
Ki = 633 nM
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CP0519733
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N-cyclopentyl-8-phenyl-9-propylpurin-6-amine
Show/Hide
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C19H23N5
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1
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| 1 |
Ki = 634 nM
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CP0383015
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methyl 3-[(6-amino-3,5-dicyano-4-pyridin-3-ylpyridin-2-yl)sulfanylmethyl]benzoate
Show/Hide
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C21H15N5O2S
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1
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| 1 |
Ki = 636 nM
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CP0472357
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N-[[1-[7-amino-2-(furan-2-yl)-[1,3]thiazolo[5,4-d]pyrimidin-5-yl]piperidin-4-yl]methyl]-3-(1,1,3-trioxo-1,2-benzothiazol-2-yl)propanamide
Show/Hide
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C25H25N7O5S2
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1
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| 1 |
Ki = 639 nM
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CP0373200
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6-[4-[2-[4-(3,5-dichloropyridin-4-yl)piperazin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H28Cl2N6O4
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1
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| 1 |
Ki = 645.65 nM
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CP0444778
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2-(2-methoxyphenyl)-5-(3-phenylpropyl)pyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C21H21N5O
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1
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| 1 |
Ki = 647 nM
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CP0381888
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8-Bromo-9-cyclobutyl-9H-adenine
Show/Hide
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C9H10BrN5
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1
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| 1 |
Ki = 660 nM
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CP0434499
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11-benzyl-13-cyclopentyl-7-ethyl-4-phenyl-5,6,8,11,12-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7,12-pentaen-10-one
Show/Hide
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C28H27N5O
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1
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| 1 |
Ki = 662.4 nM
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CP0420550
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1,3-dibutyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C28H40N6O3
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1
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| 1 |
Ki = 666 nM
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CP0427815
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1-[11-(furan-2-yl)-4-(2-phenylethyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N8O3
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1
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| 1 |
Ki = 672 nM
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CP0943821
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[3-(2-{2-[3-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)propoxy]ethoxy}ethoxy)propyl]carbamic acid tert-butyl ester
Show/Hide
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C26H38N8O6
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1
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| 1 |
Ki = 674 nM
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CP0929330
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N-((4-(Aminomethyl)cyclohexyl)methyl)-2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5yl-ammonium chloride
Show/Hide
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C19H25ClN8O
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1
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| 1 |
Ki = 682 nM
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CP0409546
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1,3-diethyl-6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H31N5O4
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1
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| 1 |
Ki = 691.83 nM
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CP0383009
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methyl 3-[(6-amino-3,5-dicyano-4-thiophen-2-ylpyridin-2-yl)sulfanylmethyl]benzoate
Show/Hide
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C20H14N4O2S2
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1
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| 1 |
Ki = 693 nM
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CP0139902
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1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-nitrophenyl)urea
Show/Hide
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C18H13N9O4
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1
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| 1 |
Ki = 695 nM
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CP0391351
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4-(furan-2-yl)-11-methyl-N-octan-2-yl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H25N7O
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1
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| 1 |
Ki = 701 nM
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CP0399711
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1,3-dimethyl-6-[4-[2-oxo-2-(4-pyridin-2-ylpiperazin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C25H26N6O4
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1
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| 1 |
Ki = 707.95 nM
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CP0409554
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3-methyl-6-[4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H31N5O4
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1
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| 1 |
Ki = 707.95 nM
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CP0465147
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8-amino-2-phenyl-6-(4-phenylmethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C24H19N5O2
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1
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| 1 |
Ki = 708 nM
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CP0546064
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4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
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C25H28N4O
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1
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| 1 |
Ki = 717 nM
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CP0439041
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2,5,8-triethyl-4,7-dihydro-1H-benzo[1,2-d:3,4-d':5,6-d'']-triimidazole
Show/Hide
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C15H18N6
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1
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| 1 |
Ki = 720 nM
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CP0537502
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4-[3-(7-amino-2-phenylpyrazolo[4,3-d]pyrimidin-5-yl)propyl]phenol
Show/Hide
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C20H19N5O
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1
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| 1 |
Ki = 722 nM
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CP0383482
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N-(2-methyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
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C19H15N5O
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1
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| 1 |
Ki = 728.1 nM
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CP0374424
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9-Allyl-8-bromo-9H-adenine
Show/Hide
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C8H8BrN5
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1
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| 1 |
Ki = 730 nM
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CP0381889
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8-Bromo-9-(2-butyl)-9H-adenine
Show/Hide
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C9H12BrN5
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1
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| 1 |
Ki = 730 nM
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CP0850599
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N2-phenethyl-9-propyl-9H-purine-2,6-diamine
Show/Hide
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C16H20N6
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1
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| 1 |
Ki = 738 nM
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CP0405392
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6-[4-[1-[4-(2-chlorophenyl)piperazin-1-yl]-1-oxopropan-2-yl]oxyphenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H28ClN5O4
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1
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| 1 |
Ki = 741.31 nM
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CP0375821
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2-methyl-6-phenylmethoxypyrazolo[3,4-c]quinolin-4-amine
Show/Hide
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C18H16N4O
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1
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| 1 |
Ki = 750 nM
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CP0882747
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2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-ylamino)ethyl-ammonium chloride
Show/Hide
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C13H15ClN8O
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1
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| 1 |
Ki = 756 nM
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CP0446156
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2-(4-hydroxypent-1-yl)-N6-methoxyadenosine
Show/Hide
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C16H21N5O6
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1
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| 1 |
Ki = 758 nM
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CP0276773
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(2R,3R,4S,5R)-2-(6-(2-methyl-benzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C18H21N5O4
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1
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| 1 |
Ki = 760 nM
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CP0514926
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2-amino-4-[4-(cyclopropylmethoxy)phenyl]-6-(1H-imidazol-2-ylmethylsulfanyl)pyridine-3,5-dicarbonitrile
Show/Hide
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C21H18N6OS
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1
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| 1 |
Ki = 764 nM
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CP0453118
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8-[4-(phenylethylamidosulfonyl)phenyl]-1-propylxanthine
Show/Hide
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C22H23N5O4S
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1
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| 1 |
Ki = 769 nM
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CP0463445
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5-(cyclohexylcarbamoylamino)-2-(furan-2-yl)-N-(2-phenylethyl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C25H27N7O3
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1
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| 1 |
Ki = 773 nM
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CP0493943
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N-(11-methyl-4-phenyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl)-2-phenylacetamide
Show/Hide
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C21H17N7O
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1
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| 1 |
Ki = 778 nM
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CP0415413
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2-(furan-2-yl)-5-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
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C15H11N5OS
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1
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| 1 |
Ki = 782 nM
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CP0315311
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(1S,2R,3S,4R,5S)-4-(6-(3-iodobenzylamino)-2-chloro-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C20H20ClIN6O3
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1
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| 1 |
Ki = 784 nM
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CP0416238
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-prop-2-ynylpiperidin-4-yl)urea
Show/Hide
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C20H21N9O2
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1
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| 1 |
Ki = 789 nM
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CP0375232
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5-[3-(4-methoxyphenyl)propyl]-2-phenylpyrazolo[4,3-d]pyrimidin-7-amine
Show/Hide
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C21H21N5O
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1
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| 1 |
Ki = 790 nM
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CP0412427
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1,3-dimethyl-6-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C21H25N5O4
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1
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| 1 |
Ki = 794.33 nM
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CP0412430
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1,3-dimethyl-6-[4-[2-oxo-2-(4-phenylpiperidin-1-yl)ethoxy]phenyl]-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C27H28N4O4
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1
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| 1 |
Ki = 794.33 nM
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CP0139906
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1-(8-tert-Butyl-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(3-chloro-phenyl)-urea
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C21H19ClN8O2
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1
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| 1 |
Ki = 796 nM
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CP0504201
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(beta-D-ribofuranosyl)adenine
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C17H22ClN5O4
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1
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| 1 |
Ki = 797 nM
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CP0414841
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N,N-diethyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C15H17N7O
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1
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| 1 |
Ki = 798 nM
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CP0442233
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1N-methyl-4-[6-(2-carbamoylmethoxy-5-chlorobenzylamino)-2-chloro-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
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C22H23Cl2N7O5
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1
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| 1 |
Ki = 800 nM
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CP0434004
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N-benzoyl-N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
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C22H18ClN5O2
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1
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| 1 |
Ki = 800 nM
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CP0451180
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N-[4-(furan-2-yl)-11-(3-phenylpropyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]naphthalene-1-carboxamide
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C30H23N7O2
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1
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| 1 |
Ki = 800 nM
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CP0400110
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3-Benzyl-9-phenyl-1-pyridin-3-yl-pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-one
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C26H18N6O
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1
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| 1 |
Ki = 805.1 nM
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CP0433856
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6-[4-[2-[4-(6-chloro-1,3-benzothiazol-2-yl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C31H33ClN6O4S
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1
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| 1 |
Ki = 812.83 nM
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CP0391350
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N-(cyclohexylmethyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H21N7O
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1
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| 1 |
Ki = 814 nM
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CP0387253
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ethyl 2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonyl]hydrazinyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C17H20N6O5
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1
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| 1 |
Ki = 827 nM
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CP0394643
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ethyl 5-(2-aminoethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C14H16N6O3
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1
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| 1 |
Ki = 829 nM
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CP0392117
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2-(4-methyl-1H-1,3-benzodiazol-2-yl)quinoxaline
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C16H12N4
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1
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| 1 |
Ki = 833 nM
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CP0399699
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(2S,3S,4R,5R)-2-(chloromethyl)-5-[6-(cyclopentylamino)purin-9-yl]oxolane-3,4-diol
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C15H20ClN5O3
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1
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| 1 |
Ki = 837 nM
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CP0514611
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2-(4-Chlorophenyl)-8-ethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
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C14H12ClN7
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1
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| 1 |
Ki = 843 nM
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CP0381032
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9-cyclobutyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C14H19N5O2
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1
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| 1 |
Ki = 847 nM
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CP0391349
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N-(2-adamantyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki = 848 nM
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CP0375913
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1N-methyl-4-[6-(2-benzyloxy-5-chlorobenzylamino)-2-chloro-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C27H26Cl2N6O4
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1
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| 1 |
Ki = 850 nM
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CP0429537
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2,6-bis(furan-2-yl)imidazo[1,2-a]pyrazin-8-amine
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C14H10N4O2
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1
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| 1 |
Ki = 854 nM
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CP0163656
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(1R,2R,3S,4R,5S)-1-Hydroxymethyl-4-[6-(3-iodo-benzylamino)-purin-9-yl]-bicyclo[3.1.0]hexane-2,3-diol
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C19H20IN5O3
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1
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| 1 |
Ki = 860 nM
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CP0409544
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6-[3-methoxy-4-[2-[4-(4-methoxyphenyl)piperidin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C29H32N4O6
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1
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| 1 |
Ki = 870.96 nM
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CP0058409
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-1-phenylpropan-2-ylamino)-9H-purin-9-yl)-tetrahydrofuran-3,4-diol
Show/Hide
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C19H23N5O4
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1
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| 1 |
Ki = 884 nM
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CP0497119
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3-chloro-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
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C19H14ClN5O
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1
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| 1 |
Ki = 886 nM
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CP0383022
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2-amino-6-(cyanomethylsulfanyl)-4-(furan-2-yl)pyridine-3,5-dicarbonitrile
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C13H7N5OS
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1
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| 1 |
Ki = 887 nM
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CP0304418
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2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C22H17N7O
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1
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| 1 |
Ki = 896 nM
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CP0496057
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-iodo-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C20H21IN6O5
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1
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| 1 |
Ki = 900 nM
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CP0388139
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N-benzhydryl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C24H19N7O
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1
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| 1 |
Ki = 900 nM
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CP0468154
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N-[(4-fluorophenyl)methyl]-2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine
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C21H15FN6O2
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1
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| 1 |
Ki = 905 nM
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CP0398706
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1,3-dibutyl-9-[4-(2-piperidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C29H42N6O3
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1
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| 1 |
Ki = 921 nM
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CP0381030
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9-[2-(cyclohexen-1-yl)ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C18H25N5O2
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1
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| 1 |
Ki = 933 nM
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CP0551159
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7-(3-piperidin-1-ylpropoxy)-4-[4-(3-piperidin-1-ylpropoxy)phenyl]-5H-indeno[1,2-d]pyrimidin-2-amine
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C33H43N5O2
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1
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| 1 |
Ki = 941 nM
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CP0403598
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6-(2-methyl-5-oxo-1H-pyrazol-3-yl)-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C16H21N5O3
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1
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| 1 |
Ki = 960 nM
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CP0400007
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N-[4-phenyl-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H21N7O
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1
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| 1 |
Ki = 963 nM
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CP0558433
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5-N-[(3-methoxyphenyl)methyl]-2-pyrazin-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
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C17H15N7OS
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1
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| 1 |
Ki = 973 nM
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CP0424432
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N-(4-methylphenyl)-7-pyrrolidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C16H17N5S
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1
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| 1 |
Ki = 974 nM
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CP0447495
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N-phenyl-7-piperidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C16H17N5S
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1
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| 1 |
Ki = 980 nM
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CP0440624
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1-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
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C20H15ClN8O
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1
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| 1 |
Ki = 987 nM
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CP0376873
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2-phenethyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C19H17N5
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1
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| 1 |
Ki = 1000 nM
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CP0494052
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N-[2-(furan-2-yl)-1,3-benzoxazol-5-yl]-2-piperidin-1-ylacetamide
Show/Hide
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C18H19N3O3
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1
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| 1 |
Ki = 1000 nM
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CP0444681
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8-[4-[4-(3-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25ClN6O4S
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1
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| 1 |
Ki = 1000 nM
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CP0398705
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1,3-dibutyl-9-[4-[2-(diethylamino)ethoxy]phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C28H42N6O3
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1
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| 1 |
Ki = 1010 nM
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CP0851034
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8-Bromo-N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine
Show/Hide
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C17H20BrN5
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1
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| 1 |
Ki = 1020 nM
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CP0468153
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N-[5-(cyclohexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
Show/Hide
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C21H21N7O2
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1
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| 1 |
Ki = 1020 nM
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CP0412439
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9-ethyl-N-(oxolan-3-yl)-8-phenylpurin-6-amine
Show/Hide
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C17H19N5O
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1
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| 1 |
Ki = 1020 nM
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CP0373206
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3-methyl-6-[4-[2-oxo-2-(4-phenylpiperidin-1-yl)ethoxy]phenyl]-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C29H32N4O4
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1
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| 1 |
Ki = 1023.29 nM
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CP0264648
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1-(2-(furan-2-yl)-8-(3-methylbut-2-enyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C23H22N8O3
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1
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| 1 |
Ki = 1025 nM
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CP0445434
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N-(1-oxo-2-phenyltriazolo[1,2-a][1,2,4]benzotriazin-5-yl)benzamide
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C22H15N5O2
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1
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| 1 |
Ki = 1030 nM
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CP0388105
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4-(furan-2-yl)-N,N,11-trimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C13H13N7O
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1
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| 1 |
Ki = 1030 nM
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CP0473554
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1,3-dibutyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H38N6O3
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1
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| 1 |
Ki = 1030 nM
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CP0471114
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8-amino-2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
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C13H13N5O2
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1
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| 1 |
Ki = 1038 nM
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CP0308558
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1-(8-ethyl-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C20H18N8O3
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1
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| 1 |
Ki = 1040 nM
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CP0399744
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6-[4-[2-(4,4-diphenylpiperidin-1-yl)-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C37H40N4O4
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1
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| 1 |
Ki = 1047.13 nM
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CP0473543
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7-chloro-N-(3,4,5-trimethoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C14H13ClN4O3S
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1
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| 1 |
Ki = 1050 nM
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CP0420533
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2,6-diphenyl-8-tButyl-1-deazapurine
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C22H21N3
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1
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| 1 |
Ki = 1055 nM
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CP0398456
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2-(4-Methoxy-phenyl)-2H-pyrazolo[3,4-c]quinolin-4-ylamine
Show/Hide
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C17H14N4O
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1
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| 1 |
Ki = 1060 nM
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CP0452422
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1-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-fluorophenyl)urea
Show/Hide
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C20H14ClFN8O
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1
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| 1 |
Ki = 1060 nM
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CP0393013
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N-cyclohexyl-8-phenyl-9-propylpurin-6-amine
Show/Hide
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C20H25N5
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1
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| 1 |
Ki = 1060 nM
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CP0441105
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N-benzyl-4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C19H17N7O
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1
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| 1 |
Ki = 1080 nM
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CP0436049
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ethyl 2-[4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidin-1-yl]acetate
Show/Hide
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C21H25N9O4
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1
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| 1 |
Ki = 1084 nM
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CP0409531
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6-[4-[2-[4-(2-chlorophenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C28H30ClN5O4
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1
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| 1 |
Ki = 1096.48 nM
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CP0860185
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2-Hydroxymethyl-5-(6-isopropylamino-2-phenylethynyl-purin-9-yl)-tetrahydro-furan-3,4-diol
Show/Hide
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C21H23N5O4
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1
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| 1 |
Ki = 1100 nM
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CP0500598
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N-[6-amino-2-(4-methoxyphenyl)-1-oxo-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl]acetamide
Show/Hide
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C18H16N6O3
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1
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| 1 |
Ki = 1100 nM
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CP0376102
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1N-methyl-4-[6-(4-amino-3-iodobenzylamino)-2-chloro-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C20H21ClIN7O3
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1
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| 1 |
Ki = 1100 nM
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CP0381892
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8-Bromo-9-(2-hydroxypropyl)-9H-adenine
Show/Hide
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C8H10BrN5O
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1
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| 1 |
Ki = 1100 nM
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CP0442950
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-methylbenzamide
Show/Hide
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C16H16ClN5O
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1
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| 1 |
Ki = 1100 nM
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CP0054348
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1-methyl-9-(oxolan-2-ylmethyl)-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C17H21N5O3
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1
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| 1 |
Ki = 1110 nM
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CP0454697
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[(2S)-1-[2-(4-methoxyanilino)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]pyrrolidin-2-yl]methanol
Show/Hide
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C17H19N5O2S
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1
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| 1 |
Ki = 1110 nM
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CP0113084
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1-(2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-nitrophenyl)urea
Show/Hide
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C20H17N9O4
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1
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| 1 |
Ki = 1115 nM
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CP0433131
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2-mercaptopyrimidine analogue, 5c
Show/Hide
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C10H15N3O2S
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1
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| 1 |
Ki = 1121 nM
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CP0383483
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4-methoxy-N-(2-phenethyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
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C27H23N5O2
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1
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| 1 |
Ki = 1136 nM
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CP0399757
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N-[(4-chlorophenyl)methyl]-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C25H25ClN10O3
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1
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| 1 |
Ki = 1137 nM
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CP0427867
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N-[2-(furan-2-yl)-5-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]benzamide
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C22H14N4O2S
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1
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| 1 |
Ki = 1144 nM
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CP0405376
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6-[4-[2-(4-hydroxy-4-phenylpiperidin-1-yl)-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C31H36N4O5
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1
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| 1 |
Ki = 1148.15 nM
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CP0467109
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N,N-dibenzyl-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
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C25H21N7O
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1
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| 1 |
Ki = 1150 nM
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CP0404908
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9-cycloheptyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C17H25N5O2
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1
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| 1 |
Ki = 1160 nM
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CP0420802
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4-[[4-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenyl]sulfonylpiperazin-1-yl]methyl]benzoic acid
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C26H28N6O6S
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1
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| 1 |
Ki = 1160 nM
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CP0176307
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9-(4-fluorophenyl)-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C16H16FN5O2
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1
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| 1 |
Ki = 1180 nM
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CP0868035
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N-benzyl-8-bromo-9-propyl-9H-purin-6-amine
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C15H16BrN5
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1
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| 1 |
Ki = 1180 nM
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CP0394564
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(2R,3R,4S,5R)-2-[6-(ethylamino)-2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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C21H23N5O5
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1
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| 1 |
Ki = 1181 nM
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CP0508354
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2-(4-Methoxyphenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
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C14H13N7O
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1
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| 1 |
Ki = 1190 nM
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CP0419833
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2-(furan-2-yl)-5-[(4-methylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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C18H15N5O3
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1
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| 1 |
Ki = 1190 nM
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CP0436054
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-propylpiperidin-4-yl)urea
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C20H25N9O2
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1
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| 1 |
Ki = 1193 nM
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CP0264646
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1-(3-Chloro-phenyl)-3-(2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-urea
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C18H13ClN8O2
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1
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| 1 |
Ki = 1195 nM
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CP0462353
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1-deoxy-1-{6-[N'-(5-bromo-furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
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C17H18BrN7O6
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1
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| 1 |
Ki = 1200 nM
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CP0390545
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6-N-cyclohexyl-9-methyl-2-N-phenylpurine-2,6-diamine
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C18H22N6
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1
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| 1 |
Ki = 1200 nM
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CP0372967
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(1S,2R,3S,4R,5S)-4-(6-(5-chloro-2-methoxybenzylamino)-2-chloro-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C21H22Cl2N6O4
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1
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| 1 |
Ki = 1200 nM
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CP0209026
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1-methyl-9-(2-phenylethyl)-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C20H21N5O2
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1
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| 1 |
Ki = 1200 nM
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CP0248931
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1-(3-chlorophenyl)-3-[2-(furan-2-yl)-8-propyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]urea
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C20H17ClN8O2
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1
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| 1 |
Ki = 1220 nM
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CP0394507
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(2R,3R,4S,5R)-2-[2-hex-1-ynyl-6-(methylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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C17H23N5O4
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1
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| 1 |
Ki = 1230 nM
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CP0929329
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(2-{2-[2-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamino)ethoxy]ethoxy}ethyl)carbamic acid tert-butyl ester
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C22H30N8O5
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1
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| 1 |
Ki = 1260 nM
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CP0082822
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(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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C17H23N5O4
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1
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| 1 |
Ki = 1270 nM
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CP0405959
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N-[8-(furan-2-yl)-9-methylpurin-6-yl]-4-phenylbenzamide
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C23H17N5O2
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1
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| 1 |
Ki = 1270 nM
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CP0445852
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7-N,7-N-dimethyl-2-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine
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C13H13N5S
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1
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| 1 |
Ki = 1270 nM
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CP0904770
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4-[({[2-(2-Furyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl]amino}carbonyl)amino]-N-(4-methylpiperazin-1-yl)piperidine-1-carboxamide Trifluoroacetate
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C25H30F3N11O5
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1
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| 1 |
Ki = 1282 nM
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CP0310622
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(1S,2R,3S,4R,5S)-4-(6-(3-bromobenzylamino)-2-chloro-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
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C20H20BrClN6O3
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1
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| 1 |
Ki = 1300 nM
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CP0846815
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1N-methyl-4-[2-chloro-6-(2,5-dichlorobenzylamino)-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
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C20H19Cl3N6O3
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1
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| 1 |
Ki = 1300 nM
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CP0447251
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8-amino-2-(4-hydroxyphenyl)-6-methyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
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C12H11N5O2
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1
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| 1 |
Ki = 1319 nM
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CP0399697
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5'-chloro-5'-deoxy-N6-((-endo-norborn-2-yl)adenosine
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C17H22ClN5O3
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1
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| 1 |
Ki = 1340 nM
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CP0123279
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9-[2-(3-chlorophenyl)ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C18H20ClN5O2
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1
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| 1 |
Ki = 1350 nM
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CP0454464
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(2R,3R,4S,5S)-2-[6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
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C16H14Cl2FN5O3
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1
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| 1 |
Ki = 1360 nM
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CP0391387
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N-butyl-4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki = 1380 nM
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CP0282756
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1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-(4-methoxyphenyl)urea
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C19H16N8O3
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1
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| 1 |
Ki = 1390 nM
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CP0145353
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(2R,3R,4S,5R)-2-(6-(3-chlorobenzylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
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C17H18ClN5O4
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1
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| 1 |
Ki = 1400 nM
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CP0425420
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(2R,3R,4S,5R)-2-(6-amino-2-(2-(5-methoxy-1H-indol-3-yl)ethoxy)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
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C21H24N6O6
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1
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| 1 |
Ki = 1400 nM
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CP0417738
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2-(4-Methoxyphenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidin-5-amine
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C21H19N7O
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1
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| 1 |
Ki = 1400 nM
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CP0902366
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N2-benzyl-9-propyl-9H-purine-2,6-diamine
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C15H18N6
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1
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| 1 |
Ki = 1400 nM
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CP0518026
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N-(4-chlorophenyl)-7-morpholin-4-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C15H14ClN5OS
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1
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| 1 |
Ki = 1400 nM
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CP0410154
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-prop-2-enylpiperidin-4-yl)urea
Show/Hide
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C20H23N9O2
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1
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| 1 |
Ki = 1423 nM
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CP0405394
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6-[3-methoxy-4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
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C27H29N5O5
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1
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| 1 |
Ki = 1445.44 nM
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CP0390093
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1-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H17ClN8O2
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1
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| 1 |
Ki = 1460 nM
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CP0378547
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N-[2-(4-methylphenyl)pyrazolo[3,4-c]quinolin-4-yl]acetamide
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C19H16N4O
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1
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| 1 |
Ki = 1500 nM
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CP0400038
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2-(4-Bromophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
Show/Hide
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C13H10BrN7
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1
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| 1 |
Ki = 1500 nM
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CP0473550
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N-(7-chloro-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)benzamide
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C12H7ClN4OS
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1
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| 1 |
Ki = 1500 nM
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CP0894368
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxyisoxazol-5-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H18N6O3
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1
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| 1 |
Ki = 1520 nM
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CP0396866
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5-(cyclohexylcarbamoylamino)-2-(furan-2-yl)-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C18H21N7O3
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1
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| 1 |
Ki = 1520 nM
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CP0424436
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7-chloro-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C11H7ClN4S
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1
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| 1 |
Ki = 1520 nM
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CP0376573
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9-cyclooctyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C18H27N5O2
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1
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| 1 |
Ki = 1530 nM
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CP0391521
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ethyl 2-[[8-[(2-ethoxy-2-oxoethyl)carbamoyl]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-yl]amino]acetate
Show/Hide
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C18H20N6O6
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1
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| 1 |
Ki = 1540 nM
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CP0409548
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6-[4-[2-(4-benzylpiperazin-1-yl)-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H29N5O4
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1
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| 1 |
Ki = 1548.82 nM
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CP0442429
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1-deoxy-1-{6-[N'-(furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
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C17H19N7O6
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1
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| 1 |
Ki = 1550 nM
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CP0445263
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[2-[(3R)-3-hydroxy-3-phenylprop-1-ynyl]-6-(methylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H21N5O5
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1
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| 1 |
Ki = 1560 nM
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CP0409547
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6-[4-[2-(4-benzhydrylpiperazin-1-yl)-2-oxoethoxy]phenyl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C37H41N5O4
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1
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| 1 |
Ki = 1584.89 nM
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CP0467107
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1-deoxy-1-{6-[N'-(5-methyl-furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C18H21N7O6
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1
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| 1 |
Ki = 1600 nM
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CP0103764
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(1R,2R,3S,4R,5S)-4-[2-Chloro-6-(3-iodo-benzylamino)-purin-9-yl]-1-hydroxymethyl-bicyclo[3.1.0]hexane-2,3-diol
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C19H19ClIN5O3
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1
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| 1 |
Ki = 1600 nM
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CP0169051
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(1S,2R,3S,4R,5S)-4-(2-chloro-6-(2,2-diphenylethylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C27H27ClN6O3
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1
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| 1 |
Ki = 1600 nM
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CP0081313
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9-(5'-Cyclopropylmethylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)-N6-(3-iodobenzyl)adenine
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C21H23IN6O3S
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1
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| 1 |
Ki = 1600 nM
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CP0399762
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8-Bromo-9-(but-3-enyl)-9H-adenine
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C9H10BrN5
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1
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| 1 |
Ki = 1600 nM
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CP0435754
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-fluorobenzamide
Show/Hide
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C15H13ClFN5O
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1
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| 1 |
Ki = 1600 nM
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CP0381031
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9-cyclohexyl-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C16H23N5O2
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1
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| 1 |
Ki = 1610 nM
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CP0489090
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6-cyclohexyl-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
Show/Hide
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C15H21N5O2
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1
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| 1 |
Ki = 1610 nM
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CP0445369
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-(3-phenylpropyl)piperidine-1-carboxamide
Show/Hide
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C27H30N10O3
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1
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| 1 |
Ki = 1641 nM
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CP0412629
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4-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]morpholine
Show/Hide
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C15H15N7O2
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1
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| 1 |
Ki = 1670 nM
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CP0435735
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1-deoxy-1-{2-chloro-6-[N'-(thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C17H18ClN7O5S
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1
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| 1 |
Ki = 1700 nM
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CP0408740
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6-N-cyclohexyl-2-N-phenyl-7H-purine-2,6-diamine
Show/Hide
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C17H20N6
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1
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| 1 |
Ki = 1700 nM
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CP0393014
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N-(oxolan-3-yl)-8-phenyl-9-propylpurin-6-amine
Show/Hide
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C18H21N5O
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1
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| 1 |
Ki = 1700 nM
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CP0042654
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1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Show/Hide
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C7H8N4O2
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2
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| 1 |
Ki = 1710 nM
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| 2 |
Ki = 7900 nM
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CP0891837
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(2R,3S,4R)-5-((R)-6-amino-2-phenylethynyl-9H-purin-3-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
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C20H19N5O4
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1
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| 1 |
Ki = 1760 nM
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CP0405781
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-[2-(4-methoxyphenyl)ethynyl]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H21N5O6
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1
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| 1 |
Ki = 1780 nM
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CP0398623
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N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]cyclohexanecarboxamide
Show/Hide
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C17H24N6O5
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1
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| 1 |
Ki = 1780 nM
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CP0412438
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N-cyclopentyl-8-(4-methoxyphenyl)-9-methylpurin-6-amine
Show/Hide
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C18H21N5O
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1
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| 1 |
Ki = 1790 nM
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CP0408824
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2-azido-N6-(5-chloro-2-methoxybenzyl)-9-(beta-D-ribofuranosyl)adenine
Show/Hide
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C18H19ClN8O5
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1
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| 1 |
Ki = 1800 nM
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CP0431049
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6-Amino-9-cyclopentyl-9H-purine
Show/Hide
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C10H13N5
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1
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| 1 |
Ki = 1800 nM
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CP0393011
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N-cyclopentyl-9-methyl-8-(4-methylphenyl)purin-6-amine
Show/Hide
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C18H21N5
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1
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| 1 |
Ki = 1800 nM
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CP0453275
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2-(5-cyano-1-pent-1-ynyl)-N6-methoxyadenosine
Show/Hide
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C17H20N6O5
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1
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| 1 |
Ki = 1820 nM
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CP0478878
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8-(4-chlorophenyl)-N-cyclopentyl-9-methylpurin-6-amine
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C17H18ClN5
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1
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| 1 |
Ki = 1820 nM
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CP0393018
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9-methyl-N-(oxolan-3-yl)-8-phenylpurin-6-amine
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C16H17N5O
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1
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| 1 |
Ki = 1830 nM
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CP0415672
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-(2-phenylethyl)piperidine-1-carboxamide
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C26H28N10O3
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1
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| 1 |
Ki = 1842 nM
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CP0877808
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4-[({[2-(2-Furyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl]amino}carbonyl)amino]-N-pyridin-4-ylpiperidine-1-carboxamide Trifluoroacetate
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C25H24F3N11O5
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1
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| 1 |
Ki = 1856 nM
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CP0386800
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ethyl 5-ethoxy-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C14H14N4O4
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1
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| 1 |
Ki = 1860 nM
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CP0424462
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1,3-dibenzyl-1-(7-chloro-[1,3]thiazolo[5,4-d]pyrimidin-2-yl)thiourea
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C20H16ClN5S2
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1
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| 1 |
Ki = 1870 nM
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CP0388152
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9-benzyl-N-(4-nitrophenyl)-2-phenylpurin-6-amine
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C24H18N6O2
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1
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| 1 |
Ki = 1900 nM
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CP0381890
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8-Bromo-9-cyclopentyl-9H-adenine
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C10H12BrN5
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1
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| 1 |
Ki = 1900 nM
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CP0429360
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N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-4-cyclohexylbutanamide
Show/Hide
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C20H30N6O5
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1
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| 1 |
Ki = 1940 nM
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CP0427861
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N-(5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
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C19H14N4OS
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1
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| 1 |
Ki = 1951 nM
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CP0463904
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(2R,3R,4S,5S)-2-[2-chloro-6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
Show/Hide
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C16H13Cl3FN5O3
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1
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| 1 |
Ki = 1960 nM
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CP0448945
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N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-cyclopentylpropanamide
Show/Hide
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C18H26N6O5
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1
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| 1 |
Ki = 2000 nM
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CP0448362
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ethyl 6-amino-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C9H11N5O2
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1
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| 1 |
Ki = 2000 nM
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CP0466058
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4-benzyl-8-methyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C26H25N7O2
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1
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| 1 |
Ki = 2010 nM
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CP0397158
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N-[5-[4-amino-6-(dimethylamino)-1,3,5-triazine-2-carbonyl]-4-phenyl-1,3-thiazol-2-yl]-4-methoxybenzamide
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C23H21N7O3S
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1
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| 1 |
Ki = 2010 nM
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CP0506236
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2-(4-Chlorophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
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C13H10ClN7
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1
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| 1 |
Ki = 2020 nM
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CP0220811
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1-{2-Furan-2-yl-8-[2-(2,4,5-tribromo-phenyl)-ethyl]-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl}-3-(4-methoxy-phenyl)-urea
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C26H19Br3N8O3
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1
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| 1 |
Ki = 2030 nM
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CP0134329
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9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
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C17H18ClN5O2
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1
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| 1 |
Ki = 2030 nM
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CP0415591
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
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C17H21Cl2N5O3
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1
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| 1 |
Ki = 2050 nM
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CP0875854
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2-chloro-N6-cyclopentyladenosine
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C17H23ClN6O4
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1
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| 1 |
Ki = 2050 nM
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CP0434009
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-fluorobenzamide
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C20H15ClFN5O
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1
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| 1 |
Ki = 2060 nM
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CP0451568
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N-(4-chlorophenyl)-7-pyrrolidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C15H14ClN5S
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1
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| 1 |
Ki = 2060 nM
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CP0428193
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1-deoxy-1-{6-[N'-(5-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-Dribofuranuronamide
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C18H21N7O5S
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1
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| 1 |
Ki = 2100 nM
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CP0275282
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2-chloro-N6-(3-iodobenzyl)-5'-N-methylcarbamoyladenosine
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C19H20ClIN6O5
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1
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| 1 |
Ki = 2100 nM
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CP0435752
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-methylbenzamide
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C18H20ClN5O
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1
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| 1 |
Ki = 2100 nM
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CP0085131
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9-(4-fluorophenyl)-1-methyl-3-prop-2-ynyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C18H16FN5O2
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1
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| 1 |
Ki = 2120 nM
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CP0459541
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4-benzyl-8-ethyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C27H27N7O2
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1
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| 1 |
Ki = 2130 nM
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CP0385048
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N-[2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-yl]benzamide
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C18H17N7O2
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1
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| 1 |
Ki = 2150 nM
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CP0503227
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2,5'-dichloro-5'-deoxy-N6-cyclopentyladenosine
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C15H19Cl2N5O3
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1
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| 1 |
Ki = 2160 nM
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CP0882746
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{4-[(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamino)methyl]cyclohexylmethyl}carbamic acid tert-butyl ester
Show/Hide
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C24H32N8O3
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1
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| 1 |
Ki = 2170 nM
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CP0494164
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3-Cyclopentyl-N-[6-cyclopentylamino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-propionamide
Show/Hide
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C23H34N6O5
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1
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| 1 |
Ki = 2180 nM
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CP0493949
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2-(4-Chlorophenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
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C20H16ClN7
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1
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| 1 |
Ki = 2180 nM
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CP0408997
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1,3-diethyl-9-[2-(4-hydroxyphenyl)ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C20H25N5O3
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1
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| 1 |
Ki = 2180 nM
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CP0474233
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2-Chloro-N6-cyclopentyl-9H-[5-deoxy-5-(2-fluorophenylthio)-beta-D-ribofuranosyl]adenine
Show/Hide
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C21H23ClFN5O3S
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1
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| 1 |
Ki = 2190 nM
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CP0065980
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9-Ethyl-9H-adenine
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C7H9N5
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1
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| 1 |
Ki = 2200 nM
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CP0435770
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-fluorobenzamide
Show/Hide
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C17H17ClFN5O
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1
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| 1 |
Ki = 2200 nM
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CP0447497
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7-N,7-N-diethyl-2-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine
Show/Hide
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C15H17N5S
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1
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| 1 |
Ki = 2210 nM
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CP0436091
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1-[1-[(4-cyanophenyl)methyl]piperidin-4-yl]-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C25H24N10O2
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1
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| 1 |
Ki = 2223 nM
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CP0474845
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N-(3-oxo-4-phenyl-2,4,5,8,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),5,7,10,12-pentaen-7-yl)benzamide
Show/Hide
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C21H14N6O2
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1
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| 1 |
Ki = 2240 nM
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CP0420734
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N-(2,6-difluorophenyl)-7-pyrrolidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C15H13F2N5S
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1
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| 1 |
Ki = 2260 nM
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CP0077413
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(2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
Show/Hide
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C15H20ClN5O4
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2
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| 1 |
Ki = 2270 nM
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| 2 |
Ki = 2300 nM
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CP0169052
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(1S,2R,3S,4R,5S)-4-(6-(3-chlorobenzylamino)-2-chloro-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C20H20Cl2N6O3
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1
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| 1 |
Ki = 2300 nM
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CP0395074
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(2R,3S,4R,5R)-2-Hydroxymethyl-5-{6-[(pyridin-3-ylmethyl)-amino]-purin-9-yl}-tetrahydro-furan-3,4-diol
Show/Hide
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C16H18N6O4
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1
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| 1 |
Ki = 2300 nM
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CP0386726
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9-Cyclopropyl-9H-adenine
Show/Hide
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C8H9N5
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1
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| 1 |
Ki = 2300 nM
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CP0448363
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ethyl 6-[(4-methylbenzoyl)amino]-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C19H21N5O3
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1
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| 1 |
Ki = 2300 nM
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CP0433855
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6-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]-2-oxoethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H29N5O5
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1
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| 1 |
Ki = 2344.23 nM
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CP0390094
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1-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
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C20H15BrN8O
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1
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| 1 |
Ki = 2360 nM
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CP0398703
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1,3-dipropyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C26H36N6O3
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1
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| 1 |
Ki = 2380 nM
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CP0456892
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10-cyclooctyl-1,3-dimethyl-6,7,8,9-tetrahydropurino[7,8-a][1,3]diazepine-2,4-dione
Show/Hide
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C19H29N5O2
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1
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| 1 |
Ki = 2400 nM
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CP0413573
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ethyl 6-[(2-phenylacetyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C24H23N5O3
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1
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| 1 |
Ki = 2400 nM
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CP0493562
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N-cyclopentyl-8-(4-fluorophenyl)-9-methylpurin-6-amine
Show/Hide
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C17H18FN5
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1
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| 1 |
Ki = 2400 nM
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CP0425839
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8-methyl-2-phenyl-[1,2,4]triazolo[1,5-a]quinoxaline
Show/Hide
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C16H12N4
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1
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| 1 |
Ki = 2401 nM
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CP0504146
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N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-2-cyclohexylacetamide
Show/Hide
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C18H26N6O5
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1
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| 1 |
Ki = 2410 nM
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CP0456671
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5-ethyl-7-(1,3-thiazol-2-yl)thieno[2,3-d]pyridazin-4-one
Show/Hide
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C11H9N3OS2
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1
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| 1 |
Ki = 2487 nM
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CP0378104
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(2R,3S,4R,5R)-2-Hydroxymethyl-5-[6-(2-phenyl-cyclopropylamino)-purin-9-yl]-tetrahydro-furan-3,4-diol
Show/Hide
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C19H21N5O4
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1
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| 1 |
Ki = 2500 nM
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CP0134324
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1,3-diethyl-9-[2-(4-methoxyphenyl)ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
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C21H27N5O3
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1
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| 1 |
Ki = 2530 nM
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CP0373122
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N-[4-(4-fluorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16FN7O
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1
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| 1 |
Ki = 2540 nM
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CP0383511
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2-(2''-(1''-(p-toluenesulfonyl)indolyl)ethyloxy)adenosine
Show/Hide
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C27H28N6O7S
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1
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| 1 |
Ki = 2570 nM
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CP0555024
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11-benzyl-7-methyl-4-phenyl-13-thiophen-2-yl-5,6,8,11,12-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7,12-pentaen-10-one
Show/Hide
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C26H19N5OS
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1
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| 1 |
Ki = 2595.4 nM
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CP0469804
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ethyl 6-amino-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C11H15N5O2
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1
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| 1 |
Ki = 2600 nM
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CP0424402
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3-furan-2-yl-10-methyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
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C14H10N4O2
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1
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| 1 |
Ki = 2608 nM
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CP0405754
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2-(3''-(1''-(p-toluenesulfonyl)indolyl)ethyloxy)adenosine
Show/Hide
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C27H28N6O7S
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1
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| 1 |
Ki = 2670 nM
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CP0405807
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2-[(4-acetylphenyl)ethynyl]-N6-methoxyadenosine
Show/Hide
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C21H21N5O6
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1
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| 1 |
Ki = 2680 nM
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CP0439714
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N-[2-(3-methylphenyl)pyrazolo[3,4-c]quinolin-4-yl]benzamide
Show/Hide
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C24H18N4O
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2
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| 1 |
Ki = 2680 nM
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| 2 |
Ki = 2860 nM
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CP0445851
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7-chloro-N-(4-chlorophenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C11H6Cl2N4S
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1
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| 1 |
Ki = 2690 nM
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CP0395584
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N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-4-(trifluoromethyl)benzamide
Show/Hide
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C16H13ClF3N5O
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1
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| 1 |
Ki = 2700 nM
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CP0441104
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N-cyclohexyl-4-(furan-2-yl)-N,11-dimethyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C18H21N7O
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1
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| 1 |
Ki = 2730 nM
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CP0453849
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ethyl 6-[(4-fluorobenzoyl)amino]-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C18H18FN5O3
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1
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| 1 |
Ki = 2800 nM
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CP0410321
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-[(4-methylphenyl)methyl]piperidine-1-carboxamide
Show/Hide
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C26H28N10O3
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1
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| 1 |
Ki = 2813 nM
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CP0446721
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7-(4-methylpiperazin-1-yl)-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C16H18N6S
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1
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| 1 |
Ki = 2840 nM
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CP0389909
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5-ethyl-7-pyridin-2-ylthieno[2,3-d]pyridazin-4-one
Show/Hide
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C13H11N3OS
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1
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| 1 |
Ki = 2869 nM
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CP0427936
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1,3-dimethyl-9-phenethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
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C18H21N5O2
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1
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| 1 |
Ki = 2890 nM
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CP0378156
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6-N-cycloheptyl-9-methyl-2-N-phenylpurine-2,6-diamine
Show/Hide
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C19H24N6
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1
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| 1 |
Ki = 2950 nM
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CP0391512
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2-(furan-2-yl)-5-(methylamino)-N-[[4-(trifluoromethyl)phenyl]methyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
Show/Hide
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C19H15F3N6O2
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1
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| 1 |
Ki = 2950 nM
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CP0448573
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methoxyamino)-2-(pyridin-2-ylethynyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Show/Hide
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C18H18N6O5
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1
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| 1 |
Ki = 2960 nM
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CP0445857
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N-(3-bromophenyl)-7-chloro-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C11H6BrClN4S
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1
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| 1 |
Ki = 2960 nM
|
|
|
|
CP0428798
|
8-[4-[4-(4-iodophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C24H25IN6O4S
|
1
|
| 1 |
Ki = 2990 nM
|
|
|
|
CP0392121
|
2-(4-(methylthio)-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
|
C16H12N4S
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0412827
|
6-amino-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxamide
Show/Hide
|
C7H8N6O
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0505419
|
2-{[4-(cyanomethyl)phenyl]ethynyl}-N6-methoxyadenosine
Show/Hide
|
C21H20N6O5
|
1
|
| 1 |
Ki = 3080 nM
|
|
|
|
CP0393019
|
8-(2-chlorophenyl)-N-cyclopentyl-9-methylpurin-6-amine
Show/Hide
|
C17H18ClN5
|
1
|
| 1 |
Ki = 3080 nM
|
|
|
|
CP0504812
|
N-[4-(4-chlorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C28H22ClN7O
|
1
|
| 1 |
Ki = 3090 nM
|
|
|
|
CP0381883
|
9-(2-Hydroxypropyl)-9H-adenine
Show/Hide
|
C8H11N5O
|
1
|
| 1 |
Ki = 3100 nM
|
|
|
|
CP0381984
|
N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
|
C20H16ClN5O
|
1
|
| 1 |
Ki = 3100 nM
|
|
|
|
CP0521215
|
2-[(4-carboxamidophenyl)ethynyl]-N6-methoxyadenosine
Show/Hide
|
C20H20N6O6
|
1
|
| 1 |
Ki = 3130 nM
|
|
|
|
CP0399474
|
2-ethynyl-N6-methoxyadenosine
Show/Hide
|
C13H15N5O5
|
1
|
| 1 |
Ki = 3140 nM
|
|
|
|
CP0389790
|
5,7-diethyl-2-phenylthieno[2,3-d]pyridazin-4-one
Show/Hide
|
C16H16N2OS
|
1
|
| 1 |
Ki = 3141 nM
|
|
|
|
CP0445229
|
US9326978, 30
Show/Hide
|
C21H20N4
|
1
|
| 1 |
Ki = 3150 nM
|
|
|
|
CP0376874
|
4-methoxy-N-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
|
C20H17N5O2
|
1
|
| 1 |
Ki = 3179 nM
|
|
|
|
CP0415546
|
N-(4-nitrophenyl)-7-pyrrolidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
|
C15H14N6O2S
|
1
|
| 1 |
Ki = 3180 nM
|
|
|
|
CP0428191
|
1-deoxy-1-{2-chloro-6-[N'-(1-H-pyrrole-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H19ClN8O5
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0435152
|
8-Br-adenine
Show/Hide
|
C5H4BrN5
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0412573
|
4-(furan-2-yl)-11-methyl-N-(2,3,3-trimethylbutan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C18H23N7O
|
1
|
| 1 |
Ki = 3230 nM
|
|
|
|
CP0378926
|
(1S,2R,3S,4R,5S)-4-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C18H23ClN6O3
|
1
|
| 1 |
Ki = 3250 nM
|
|
|
|
CP0445372
|
N-[(4-fluorophenyl)methyl]-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
|
C25H25FN10O3
|
1
|
| 1 |
Ki = 3255 nM
|
|
|
|
CP0151608
|
1-[2-Furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-(4-methoxy-phenyl)-urea
Show/Hide
|
C30H24N8O3
|
1
|
| 1 |
Ki = 3260 nM
|
|
|
|
CP0424435
|
[(2S)-1-[2-(2,6-difluoroanilino)-[1,3]thiazolo[5,4-d]pyrimidin-7-yl]pyrrolidin-2-yl]methanol
Show/Hide
|
C16H15F2N5OS
|
1
|
| 1 |
Ki = 3260 nM
|
|
|
|
CP0446021
|
6-(4-hydroxycyclohexyl)-2,4-dimethyl-7,8-dihydropurino[7,8-a]imidazole-1,3-dione
Show/Hide
|
C15H21N5O3
|
1
|
| 1 |
Ki = 3270 nM
|
|
|
|
CP0378165
|
3-furan-2-yl-10-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C19H12N4O2
|
1
|
| 1 |
Ki = 3277 nM
|
|
|
|
CP0412407
|
1-deoxy-1-{2-chloro-6-[N'-(thiophene-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C17H18ClN7O5S
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0395576
|
4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
|
C8H10ClN5
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0453426
|
ethyl 6-benzamido-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C18H19N5O3
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0456672
|
7-(1,3-thiazol-2-yl)-5H-thieno[2,3-d]pyridazin-4-one
Show/Hide
|
C9H5N3OS2
|
1
|
| 1 |
Ki = 3392 nM
|
|
|
|
CP0419600
|
2-[4-(ethylsulfanyl)-1H-1,3-benzodiazol-2-yl]quinoxaline
Show/Hide
|
C17H14N4S
|
1
|
| 1 |
Ki = 3440 nM
|
|
|
|
CP0386788
|
2-anilino-N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C26H24N4O2S2
|
1
|
| 1 |
Ki = 3440 nM
|
|
|
|
CP0468736
|
8-amino-2-(4-aminophenyl)-6-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C17H14N6O
|
1
|
| 1 |
Ki = 3480 nM
|
|
|
|
CP0469079
|
N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
|
C17H18ClN5O
|
1
|
| 1 |
Ki = 3500 nM
|
|
|
|
CP0433871
|
6-[4-[2-(4,4-diphenylpiperidin-1-yl)-2-oxoethoxy]phenyl]-3-methyl-1-propyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
|
C35H36N4O4
|
1
|
| 1 |
Ki = 3548.13 nM
|
|
|
|
CP0451548
|
7-chloro-N-(4-methoxyphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
|
C12H9ClN4OS
|
1
|
| 1 |
Ki = 3570 nM
|
|
|
|
CP0369563
|
4-benzamido-2-(4-methoxyphenyl)-1,2-dihydro-1,2,4-triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C23H17N5O3
|
1
|
| 1 |
Ki = 3585 nM
|
|
|
|
CP0102757
|
1-(3-Chloro-phenyl)-3-{2-furan-2-yl-8-[2-(2,4,5-tribromo-phenyl)-ethyl]-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl}-urea
Show/Hide
|
C25H16Br3ClN8O2
|
1
|
| 1 |
Ki = 3600 nM
|
|
|
|
CP0396864
|
5-(benzylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C17H13N5O3
|
1
|
| 1 |
Ki = 3660 nM
|
|
|
|
CP0419826
|
5-(ethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C12H11N5O3
|
1
|
| 1 |
Ki = 3680 nM
|
|
|
|
CP0885806
|
1N-methyl-4-[2-chloro-6-(3-methylbenzylamino)-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C21H23ClN6O3
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0395639
|
4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
|
C13H12ClN5
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0418074
|
ethyl 6-benzamido-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C23H21N5O3
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0388499
|
8-(4-(4-(4-Methoxyphenyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
|
C25H28N6O5S
|
1
|
| 1 |
Ki = 3720 nM
|
|
|
|
CP0085132
|
9-[(3,5-dichlorophenyl)methyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C17H17Cl2N5O2
|
1
|
| 1 |
Ki = 3780 nM
|
|
|
|
CP0065233
|
4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
Show/Hide
|
C14H14N4O5S
|
1
|
| 1 |
Ki = 3790 nM
|
|
|
|
CP0435709
|
1-deoxy-1-{2-chloro-6-[N'-(3-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C18H20ClN7O5S
|
1
|
| 1 |
Ki = 3800 nM
|
|
|
|
CP0845348
|
1N-methyl-4-[2-chloro-6-(2-methylbenzylamino)-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C21H23ClN6O3
|
1
|
| 1 |
Ki = 3800 nM
|
|
|
|
CP0498141
|
2-(3''-(benzoimidazole-1''-yl)ethyloxy)adenosine
Show/Hide
|
C19H21N7O5
|
1
|
| 1 |
Ki = 3870 nM
|
|
|
|
CP0474947
|
9-(3-Hydroxypropyl)-9H-adenine
Show/Hide
|
C8H11N5O
|
1
|
| 1 |
Ki = 3900 nM
|
|
|
|
CP0902328
|
N'-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)hydrazine carboxylic acid tert-butyl ester
Show/Hide
|
C16H18N8O3
|
1
|
| 1 |
Ki = 3900 nM
|
|
|
|
CP0446165
|
2-[(4-fluorophenyl)ethynyl]-N6-methoxyadenosine
Show/Hide
|
C19H18FN5O5
|
1
|
| 1 |
Ki = 3960 nM
|
|
|
|
CP0537188
|
N-(2,5-diphenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)furan-2-carboxamide
Show/Hide
|
C22H14N4O2S
|
1
|
| 1 |
Ki = 3980 nM
|
|
|
|
CP0490639
|
8-Bromo-9-(2,3-dihydroxypropyl)-9H-adenine
Show/Hide
|
C8H10BrN5O2
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0484553
|
N-[4-(4-fluorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
|
C27H20FN7O
|
1
|
| 1 |
Ki = 4040 nM
|
|
|
|
CP0458574
|
6-(3-hydroxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C17H12N4O3
|
1
|
| 1 |
Ki = 4066 nM
|
|
|
|
CP0467106
|
1-deoxy-1-{2-chloro-6-[N'-(5-methyl-thiophene-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C18H20ClN7O5S
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0471937
|
(E)-N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-phenylprop-2-enamide
Show/Hide
|
C19H20N6O5
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0381881
|
9-Isopropyl-9H-adenine
Show/Hide
|
C8H11N5
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0395583
|
4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-amine
Show/Hide
|
C10H14ClN5
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0390582
|
6-N-cycloheptyl-2-N-phenyl-7H-purine-2,6-diamine
Show/Hide
|
C18H22N6
|
1
|
| 1 |
Ki = 4120 nM
|
|
|
|
CP0471420
|
2-mercaptopyrimidine analogue, 5k
Show/Hide
|
C16H18ClN3O2S
|
1
|
| 1 |
Ki = 4149 nM
|
|
|
|
CP0457533
|
4-N-(9-benzyl-2-phenylpurin-6-yl)benzene-1,4-diamine
Show/Hide
|
C24H20N6
|
2
|
| 1 |
Ki = 4170 nM
|
|
|
| 2 |
Ki = 5737 nM
|
|
|
|
CP0418077
|
ethyl 6-[(4-bromobenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C23H20BrN5O3
|
1
|
| 1 |
Ki = 4200 nM
|
|
|
|
CP0442071
|
2-[(4-acetylphenyl)ethynyl]-N6-methoxy-5'-N-ethylcarboxamidoadenosine
Show/Hide
|
C23H24N6O6
|
1
|
| 1 |
Ki = 4210 nM
|
|
|
|
CP0405806
|
(2S,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-(2-phenylethynyl)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C19H19N5O5
|
1
|
| 1 |
Ki = 4290 nM
|
|
|
|
CP0437168
|
(2R,3R,4S,5R)-2-[6-(4-chloro-2-fluoroanilino)-2-(3,5-dimethylphenyl)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C29H29ClFN7O3
|
1
|
| 1 |
Ki = 4320 nM
|
|
|
|
CP0448419
|
(3R,4S,5R)-2-[6-(ethylamino)-2-(2-phenylethynyl)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
|
C20H21N5O4
|
1
|
| 1 |
Ki = 4450 nM
|
|
|
|
CP0392989
|
9-(2-(1H-indol-3-yl)ethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
Show/Hide
|
C20H22N6O2
|
1
|
| 1 |
Ki = 4560 nM
|
|
|
|
CP0405780
|
N-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-phenylpropanamide
Show/Hide
|
C19H22N6O5
|
1
|
| 1 |
Ki = 4570 nM
|
|
|
|
CP0399738
|
(2R,3R,4S,5R)-2-(2-chloro-6-((R)-tetrahydrofuran-3-ylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
|
C14H18ClN5O5
|
1
|
| 1 |
Ki = 4590 nM
|
|
|
|
CP0442073
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-(methoxyamino)-2-[2-(4-methylphenyl)ethynyl]purin-9-yl]oxolane-2-carboxamide
Show/Hide
|
C22H24N6O5
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0395582
|
N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
|
C15H14ClN5O
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0137808
|
9-(3,5-dichlorophenyl)-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C16H15Cl2N5O2
|
1
|
| 1 |
Ki = 4610 nM
|
|
|
|
CP0435753
|
N-(4-chloro-2-propan-2-ylpyrazolo[3,4-d]pyrimidin-6-yl)-2-phenylacetamide
Show/Hide
|
C16H16ClN5O
|
1
|
| 1 |
Ki = 4700 nM
|
|
|
|
CP0439435
|
N-benzoyl-N-(1-oxo-2-phenyltriazolo[1,2-a][1,2,4]benzotriazin-5-yl)benzamide
Show/Hide
|
C29H19N5O3
|
1
|
| 1 |
Ki = 4800 nM
|
|
|
|
CP0161397
|
(1S,2R,3S,4R,5S)-4-(2-chloro-6-(2-phenylcyclopropylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
|
C22H23ClN6O3
|
1
|
| 1 |
Ki = 4800 nM
|
|
|
|
CP0467851
|
9-Cyclobutyl-9H-adenine
Show/Hide
|
C9H11N5
|
1
|
| 1 |
Ki = 4800 nM
|
|
|
|
CP0448364
|
ethyl 6-amino-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C16H17N5O2
|
1
|
| 1 |
Ki = 4800 nM
|
|
|
|
CP0408234
|
6-amino-4-benzamido-1,2-dihydro-2-phenyl-1,2,4-triazolo[4,3-a]quinoxalin-1-one
Show/Hide
|
C22H16N6O2
|
1
|
| 1 |
Ki = 4850 nM
|
|
|
|
CP0465318
|
N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C24H19N5OS2
|
1
|
| 1 |
Ki = 4870 nM
|
|
|
|
CP0381885
|
8-Bromo-9-phenylethyl-9H-adenine
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C13H12BrN5
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1
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| 1 |
Ki = 4900 nM
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CP0421987
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N-(2-benzylpyrazolo[3,4-d]pyrimidin-4-yl)-3-chlorobenzamide
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C19H14ClN5O
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1
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| 1 |
Ki = 4900 nM
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CP0420727
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7-chloro-N-(4-methylphenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C12H9ClN4S
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1
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| 1 |
Ki = 4930 nM
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CP0428091
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1-deoxy-1-{2-chloro-6-[N'-(furan-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
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C17H18ClN7O6
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1
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| 1 |
Ki = 4950 nM
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CP0445453
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ethyl 6-amino-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C13H19N5O2
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1
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| 1 |
Ki = 5000 nM
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CP0454468
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(2R,3R,4S,5R)-2-[2-(3,5-dimethylphenyl)-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
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C27H33N7O4
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1
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| 1 |
Ki = 5090 nM
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CP0849058
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1N-methyl-4-[2-chloro-6-(3-fluorobenzylamino)-9H-9-purinyl]-2,3-dihydroxy-(1S,2R,3S,4R,5S)-bicyclo[3.1.0]hexane-1-carboxamide
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C20H20ClFN6O3
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1
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| 1 |
Ki = 5100 nM
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CP0433870
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(2R,3R,4S,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(2-fluorophenyl)sulfanylmethyl]oxolane-3,4-diol
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C21H24FN5O3S
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1
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| 1 |
Ki = 5170 nM
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CP0507288
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US9326978, 31
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C22H22N4
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1
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| 1 |
Ki = 5220 nM
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CP0149067
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9-[2-(3,4-dichlorophenyl)ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C18H19Cl2N5O2
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1
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| 1 |
Ki = 5250 nM
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CP0453274
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(2S,3S,4R)-3,4-dihydroxy-5-((S)-2-iodo-6-methoxyamino-9H-purin-3-yl)-tetrahydro-furan-2-carboxylic acid ethylamide
Show/Hide
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C13H17IN6O5
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1
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| 1 |
Ki = 5290 nM
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CP0379845
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5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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C19H17N5O5
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1
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| 1 |
Ki = 5320 nM
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CP0435750
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N-benzoyl-N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
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C27H20ClN5O2
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1
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| 1 |
Ki = 5400 nM
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CP0085151
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9-(4-chlorophenethyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione
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C18H20ClN5O2
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1
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| 1 |
Ki = 5610 nM
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CP0441634
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N-[6-(cyclopentylamino)-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-3-phenylpropanamide
Show/Hide
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C24H30N6O5
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1
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| 1 |
Ki = 5660 nM
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CP0379394
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N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-methyl-2-(4-methylanilino)-1,3-thiazole-5-carboxamide
Show/Hide
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C21H20N4OS2
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1
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| 1 |
Ki = 5670 nM
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CP0431437
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ethyl 2-(2,2-dimethylpropyl)-6-[(2-phenylacetyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C21H25N5O3
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1
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| 1 |
Ki = 5700 nM
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CP0544755
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ethyl 2-(2,2-dimethylpropyl)-6-[(4-fluorobenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
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C20H22FN5O3
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1
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| 1 |
Ki = 5700 nM
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CP0378996
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-(2-trimethylsilylethynyl)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C16H23N5O5Si
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1
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| 1 |
Ki = 5740 nM
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CP0437158
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(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-2-(3,5-dimethylphenyl)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
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C28H35N7O3
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1
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| 1 |
Ki = 5870 nM
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CP0471024
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1-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-fluorophenyl)urea
Show/Hide
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C20H14BrFN8O
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1
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| 1 |
Ki = 5930 nM
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CP0396622
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N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C22H17N5O2S2
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1
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| 1 |
Ki = 5950 nM
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CP0453430
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2-(4-Chloro-phenyl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C20H16ClN7
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2
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| 1 |
Ki = 5970 nM
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| 2 |
Ki > 1000 nM
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CP0442763
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(2R,3R,4S,5R)-2-[6-[(2-chloro-5-methoxyphenyl)methylamino]-2-[4-(cyclopentylmethyl)triazol-1-yl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Show/Hide
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C26H31ClN8O5
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1
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| 1 |
Ki = 6000 nM
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CP0381896
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8-Bromo-9-isobutyl-9H-adenine
Show/Hide
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C9H12BrN5
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1
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| 1 |
Ki = 6000 nM
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CP0418072
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ethyl 6-[(4-methylbenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C24H23N5O3
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1
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| 1 |
Ki = 6000 nM
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CP0421196
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6-N-cyclohexyl-2-N-[4-(dimethylamino)phenyl]-7H-purine-2,6-diamine
Show/Hide
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C19H25N7
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1
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| 1 |
Ki = 6100 nM
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CP0381884
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9-Benzyl-8-bromo-9H-adenine
Show/Hide
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C12H10BrN5
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1
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| 1 |
Ki = 6100 nM
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CP0481161
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ethyl 6-[(4-fluorobenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H20FN5O3
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1
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| 1 |
Ki = 6100 nM
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CP0397612
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7-ethoxy-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C13H12N6O2
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1
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| 1 |
Ki = 6120 nM
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CP0382247
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(1S,2R,3S,4R,5S)-2,3-Dihydroxy-4-[6-(3-iodo-benzylamino)-purin-9-yl]-bicyclo[3.1.0]hexane-1-carboxylic acid methylamide
Show/Hide
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C20H21IN6O3
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1
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| 1 |
Ki = 6200 nM
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CP0374010
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N-[5-(4-methylbenzoyl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
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C24H18N2O2S
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1
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| 1 |
Ki = 6250 nM
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CP0442072
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2-[(4-fuorophenyl)ethynyl]-N6-methoxy-5'-N-ethylcarboxamidoadenosine
Show/Hide
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C21H21FN6O5
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1
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| 1 |
Ki = 6290 nM
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CP0419756
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-(2-pyridin-4-ylethynyl)purin-9-yl]oxolane-3,4-diol
Show/Hide
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C18H18N6O5
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1
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| 1 |
Ki = 6310 nM
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CP0393012
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N-cyclopentyl-9-methyl-8-pyridin-3-ylpurin-6-amine
Show/Hide
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C16H18N6
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1
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| 1 |
Ki = 6330 nM
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CP0708191
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TECADENOSON
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C14H19N5O5
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1
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| 1 |
Ki = 6390 nM
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CP0379818
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5-[(4-fluorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H12FN5O3
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1
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| 1 |
Ki = 6390 nM
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CP0847898
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(1S,2R,3S,4R,5S)-4-(6-(cyclopentylamino)-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C18H24N6O3
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1
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| 1 |
Ki = 6420 nM
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CP0388104
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2-[ethyl-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]amino]ethanol
Show/Hide
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C15H17N7O2
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1
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| 1 |
Ki = 6430 nM
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CP0398408
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ethyl 2-[[2-anilino-4-(dimethylamino)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
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C23H26N4O3S2
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1
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| 1 |
Ki = 6450 nM
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CP0437021
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-(methoxyamino)-2-(2-pyridin-2-ylethynyl)purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C20H21N7O5
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1
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| 1 |
Ki = 6460 nM
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CP0379837
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ethyl 5-(dimethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C14H15N5O3
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1
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| 1 |
Ki = 6480 nM
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CP0521216
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-[2-(4-pentylphenyl)ethynyl]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C24H29N5O5
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1
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| 1 |
Ki = 6520 nM
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CP0505418
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(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-(methoxyamino)-2-(2-phenylethynyl)purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C21H22N6O5
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1
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| 1 |
Ki = 6660 nM
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CP0394400
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6-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethoxy]-3-methoxyphenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C26H26N4O5
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1
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| 1 |
Ki = 6760.83 nM
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CP0437160
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(2R,3R,4S,5R)-2-[6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
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C21H21ClFN7O3
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1
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| 1 |
Ki = 6830 nM
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CP0219570
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9-METHYL-9H-PURIN-6-AMINE
Show/Hide
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C6H7N5
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1
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| 1 |
Ki = 6900 nM
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CP0460007
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11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C14H10F3N7
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1
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| 1 |
Ki = 6930 nM
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CP0393022
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N-cyclopentyl-9-methyl-8-(2-methylphenyl)purin-6-amine
Show/Hide
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C18H21N5
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1
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| 1 |
Ki = 6980 nM
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CP0388418
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2-(4-Acetylphenyl)ethynyl-N6-methyl-5'-N-methylcarboxamidoadenosine
Show/Hide
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C21H22N6O5
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1
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| 1 |
Ki = 7030 nM
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CP0412435
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6-[2-methoxy-4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C27H29N5O5
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1
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| 1 |
Ki = 7079.46 nM
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CP0448366
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ethyl 2-methyl-6-[(2-phenylacetyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C17H17N5O3
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1
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| 1 |
Ki = 7300 nM
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CP0900160
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(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(4-phenyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C25H18FN5OS
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1
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| 1 |
Ki = 7410 nM
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CP0799798
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8-Hydroxy-3-(thiophen-2-yl)coumarin
Show/Hide
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C13H8O3S
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1
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| 1 |
Ki = 7480 nM
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CP0467110
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4-(furan-2-yl)-11-methyl-N,N-dipentyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
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C21H29N7O
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1
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| 1 |
Ki = 7490 nM
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CP0418073
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ethyl 2-(2-phenylethyl)-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C24H20F3N5O3
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1
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| 1 |
Ki = 7500 nM
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CP0414365
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2-(furan-2-yl)-5-(propan-2-ylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C13H13N5O3
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1
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| 1 |
Ki = 7660 nM
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CP0397419
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4-(furan-2-yl)-11-methyl-7-(4-methylpiperazin-1-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
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C16H18N8O
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1
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| 1 |
Ki = 7690 nM
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CP0917244
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CAY10498
Show/Hide
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C18H20N6
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1
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| 1 |
Ki = 7730 nM
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CP0441727
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2-Cyclohexyl-N-[9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-ethylamino-9H-purin-2-yl]-acetamide
Show/Hide
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C20H30N6O5
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1
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| 1 |
Ki = 7750 nM
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CP0431051
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9-Butyl-9H-adenine
Show/Hide
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C9H13N5
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1
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| 1 |
Ki = 7800 nM
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CP0911940
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(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(4-methyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
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C20H16FN5OS
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1
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| 1 |
Ki = 8040 nM
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CP0445861
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7-chloro-N-(2,6-difluorophenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C11H5ClF2N4S
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1
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| 1 |
Ki = 8110 nM
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CP0463449
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ethyl 2-(furan-2-yl)-5-piperidin-1-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C17H19N5O3
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1
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| 1 |
Ki = 8180 nM
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CP0437023
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-[2-[3-(trifluoromethyl)phenyl]ethynyl]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H18F3N5O5
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1
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| 1 |
Ki = 8270 nM
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CP0477668
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N-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16ClN7O
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1
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| 1 |
Ki = 8320 nM
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CP0445854
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7-(4-ethylpiperazin-1-yl)-N-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C17H20N6S
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1
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| 1 |
Ki = 8390 nM
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CP0468299
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1-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C21H17BrN8O2
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1
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| 1 |
Ki = 8400 nM
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CP0044933
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9-Benzyl-9H-adenine
Show/Hide
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C12H11N5
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1
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| 1 |
Ki = 8500 nM
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CP0135358
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(S)-DHPA
Show/Hide
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C8H11N5O2
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1
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| 1 |
Ki = 8500 nM
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CP0381887
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9-But-3-enyl-9H-adenine
Show/Hide
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C9H11N5
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1
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| 1 |
Ki = 8500 nM
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CP0270742
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-(methylamino)-2-(phenylethynyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diol
Show/Hide
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C19H19N5O4
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1
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| 1 |
Ki = 8530 nM
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CP0395636
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-2-phenylacetamide
Show/Hide
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C21H18ClN5O
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1
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| 1 |
Ki = 8600 nM
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CP0454470
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(2S,3S,4R,5R)-2-(chloromethyl)-5-[2-chloro-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C14H17Cl2N5O4
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1
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| 1 |
Ki = 8680 nM
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CP0391188
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2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-N-methylthiocarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
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C18H25ClN6O4S
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1
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| 1 |
Ki = 8760 nM
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CP0433869
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(2R,3R,4R,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(hydroxymethyl)-3-methyloxolane-3,4-diol
Show/Hide
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C18H25N5O4
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1
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| 1 |
Ki = 8780 nM
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CP0489124
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N-[5-(4-oxo-3H-quinazolin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
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C22H14N4O3S
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1
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| 1 |
Ki = 8780 nM
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CP0418718
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ethyl 6-[(2-phenylacetyl)amino]-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
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C19H21N5O3
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1
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| 1 |
Ki = 8800 nM
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CP0871830
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(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(4-phenyl-2-(phenylamino)thiazol-5-yl)methanone
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C26H21N5O2S
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1
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| 1 |
Ki = 8840 nM
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CP0473551
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N-phenyl-7-piperazin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C15H16N6S
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1
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| 1 |
Ki = 9090 nM
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CP0395637
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4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-amine
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C6H6ClN5
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1
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| 1 |
Ki = 9100 nM
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CP0853606
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N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine
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C17H22N6
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1
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| 1 |
Ki = 9110 nM
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CP0418068
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6-amino-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxamide
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C9H12N6O
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1
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| 1 |
Ki = 9200 nM
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CP0394624
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2-(furan-2-yl)-5-(methylamino)-N-[(4-phenylphenyl)methyl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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C24H20N6O2
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1
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| 1 |
Ki = 9390 nM
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CP0437161
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(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)-2-chloropurin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
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C22H28ClN7O3
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1
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| 1 |
Ki = 9430 nM
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CP0379939
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ethyl 2-(furan-2-yl)-5-methylsulfanyl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C13H12N4O3S
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1
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| 1 |
Ki = 9500 nM
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CP0428385
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(2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol
Show/Hide
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C16H22ClN5O4
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1
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| 1 |
Ki = 9580 nM
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CP0374425
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9-Phenethyladenine
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C13H13N5
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1
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| 1 |
Ki = 9600 nM
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CP0385412
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9-Propyl-9H-adenine
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C8H11N5
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1
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| 1 |
Ki = 9600 nM
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CP0436832
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2-(4-Nitrophenyl)-8-methylpyrazolo[4,3-e]1,2,4-triazolo[1,5-c]-pyrimidin-5-amine
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C13H10N8O2
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1
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| 1 |
Ki = 9650 nM
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CP0386848
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4-O-ethyl 2-O-methyl 5-[[4-(dimethylamino)-2-(4-methoxyanilino)-1,3-thiazole-5-carbonyl]amino]-3-methylthiophene-2,4-dicarboxylate
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C23H26N4O6S2
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1
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| 1 |
Ki = 9660 nM
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CP0730942
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8-Hydroxy-3-(thiophen-3-yl)coumarin
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C13H8O3S
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1
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| 1 |
Ki = 9870 nM
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CP0395640
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N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-methylbenzamide
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C21H18ClN5O
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1
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| 1 |
Ki = 9900 nM
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CP0904720
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7,8-dihydroxy-3-(thiophen-2-yl)-2H-chromen-2-one
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C13H8O4S
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1
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| 1 |
Ki = 9980 nM
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CP0139904
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1-(3-Chloro-phenyl)-3-[2-furan-2-yl-8-(2-naphthalen-1-yl-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea
Show/Hide
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C29H21ClN8O2
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1
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| 1 |
Ki > 10000 nM
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CP0377686
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8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
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C24H25ClN6O4S
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1
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| 1 |
Ki > 10000 nM
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CP0001582
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2-(4-Methoxy-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
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C16H12N4O3
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1
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| 1 |
Ki > 10000 nM
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CP0001583
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8-Chloro-2-phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C15H9ClN4O2
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1
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| 1 |
Ki > 10000 nM
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CP0004429
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2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C15H10N4O2
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1
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| 1 |
Ki > 10000 nM
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CP0424321
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4-methoxy-N-(1-oxo-2-p-tolyl-1H-3,3,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-benzamide
Show/Hide
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C24H19N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0426978
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2-(4-Chloro-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C15H9ClN4O2
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1
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| 1 |
Ki > 10000 nM
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CP0428491
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8-Chloro-2-(4-chloro-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C15H8Cl2N4O2
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1
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| 1 |
Ki > 10000 nM
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CP0428493
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3-chloro-N-(8-chloro-1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-benzamide
Show/Hide
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C22H13Cl2N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0439430
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4-methoxy-N-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-benzamide
Show/Hide
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C23H17N5O3
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1
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| 1 |
Ki > 10000 nM
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CP0439431
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2-(4-fluoro-phenyl)-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C15H9FN4O2
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1
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| 1 |
Ki > 10000 nM
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CP0445433
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N-[9-chloro-2-(4-methylphenyl)-1-oxotriazolo[1,2-a][1,2,4]benzotriazin-5-yl]-4-methoxybenzamide
Show/Hide
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C24H18ClN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0477936
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N-[2-(4-chlorophenyl)-1-oxotriazolo[1,2-a][1,2,4]benzotriazin-5-yl]-4-methoxybenzamide
Show/Hide
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C23H16ClN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0477937
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3-chloro-N-(1-oxo-2-phenyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-benzamide
Show/Hide
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C22H14ClN5O2
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1
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| 1 |
Ki > 10000 nM
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CP0484225
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N-(9-chloro-1-oxo-2-phenyltriazolo[1,2-a][1,2,4]benzotriazin-5-yl)-4-methoxybenzamide
Show/Hide
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C23H16ClN5O3
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1
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| 1 |
Ki > 10000 nM
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CP0495633
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3-chloro-N-(1-oxo-2-p-tolyl-1H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalen-4-yl)-benzamide
Show/Hide
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C23H16ClN5O2
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1
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| 1 |
Ki > 10000 nM
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CP0500876
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8-chloro-2-p-tolyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C16H11ClN4O2
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1
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| 1 |
Ki > 10000 nM
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CP0513865
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2-p-Tolyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphthalene-1,4-dione
Show/Hide
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C16H12N4O2
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1
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| 1 |
Ki > 10000 nM
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CP0082002
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6-N-cyclohexyl-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine
Show/Hide
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C21H27N7O
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1
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| 1 |
Ki > 10000 nM
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CP0348781
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(2R,3R,4S,5R)-2-(6-(bicyclo[2.2.1]heptan-7-ylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
Show/Hide
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C17H23N5O4
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1
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| 1 |
Ki > 10000 nM
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CP0847899
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(1S,2R,3S,4R,5S)-4-(6-(bicyclo[2.2.1]heptan-7-ylamino)-2-chloro-9H-purin-9-yl)-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Show/Hide
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C20H25ClN6O3
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1
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| 1 |
Ki > 10000 nM
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CP0040132
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2,2 -(4H-1,2,4-triazole-3,5-diyl)dipyridine
Show/Hide
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C12H9N5
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1
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| 1 |
Ki > 10000 nM
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CP0392118
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2-(4-chloro-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C15H9ClN4
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1
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| 1 |
Ki > 10000 nM
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CP0392120
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2-ethyl-5,8-dimethyl-4,7-dihydro-1H-benzo[1,2-d:3,4-d':5,6-d'']-triimidazole
Show/Hide
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C13H14N6
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1
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| 1 |
Ki > 10000 nM
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CP0403419
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2,5,8-trimethyl-4,7-dihydro-1H-benzo[1,2-d:3,4-d :5,6-d ]triimidazole
Show/Hide
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C12H12N6
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1
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| 1 |
Ki > 10000 nM
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CP0403457
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2-(4,6-dichloro-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C15H8Cl2N4
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1
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| 1 |
Ki > 10000 nM
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CP0436874
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2-(6-chloro-4-methyl-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C16H11ClN4
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1
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| 1 |
Ki > 10000 nM
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CP0439042
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10-thia-1,4,5,6,8-pentazatricyclo[7.3.0.03,7]dodeca-3,6,8,11-tetraen-2-one
Show/Hide
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C6H3N5OS
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1
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| 1 |
Ki > 10000 nM
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CP0439043
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2-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C17H14N4
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1
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| 1 |
Ki > 10000 nM
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CP0439044
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2-(7H-purin-8-yl)quinoxaline
Show/Hide
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C13H8N6
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1
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| 1 |
Ki > 10000 nM
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CP0453444
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2-(4-nitro-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C15H9N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0453445
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2-(5-chloro-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C15H9ClN4
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1
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| 1 |
Ki > 10000 nM
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CP0456782
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2-(5-methyl-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C16H12N4
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1
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| 1 |
Ki > 10000 nM
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CP0456783
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2-(1H-imidazo[4,5-b]pyridin-2-yl)quinoxaline
Show/Hide
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C14H9N5
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1
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| 1 |
Ki > 10000 nM
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CP0469403
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3-(3-chloro-1H-pyrazol-5-yl)-1,2-dihydroquinoxalin-2-one
Show/Hide
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C11H7ClN4O
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1
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| 1 |
Ki > 10000 nM
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CP0469413
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2-(5-methoxy-1H-benzo[d]imidazol-2-yl)quinoxaline
Show/Hide
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C16H12N4O
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1
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| 1 |
Ki > 10000 nM
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CP0853841
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7-methyl-6,7-dihydro[1,3]thiazolo[3,2-a][1,2,3]traizolo[4,5-d]pyrimidin-9-(1H)-one
Show/Hide
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C7H7N5OS
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1
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| 1 |
Ki > 10000 nM
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CP0853842
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6,7-Dihydro-3H-thiazolo[3,2-a][1,2,3]triazolo[4,5-d]pyrimidin-9-one
Show/Hide
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C6H5N5OS
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1
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| 1 |
Ki > 10000 nM
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CP0881040
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7,8-Dihydro-3H,6H-5-thia-1,2,3,4,8a-pentaaza-cyclopenta[b]naphthalen-9-one
Show/Hide
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C7H7N5OS
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1
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| 1 |
Ki > 10000 nM
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CP0913758
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2-(1H-imidazo[4,5-c]pyridin-2-yl)quinoxaline
Show/Hide
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C14H9N5
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1
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| 1 |
Ki > 10000 nM
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CP0064086
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(2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-2-chloro-9H-purin-9-yl)-3,4-dihydroxy-N,N-dimethyl-tetrahydrothiophene-2-carboxamide
Show/Hide
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C19H20ClIN6O3S
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1
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| 1 |
Ki > 10000 nM
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CP0170985
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(2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-2-chloro-9H-purin-9-yl)-3,4-dihydroxy-N,N-dimethyl-tetrahydrofuran-2-carboxamide
Show/Hide
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C19H20ClIN6O4
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1
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| 1 |
Ki > 10000 nM
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CP0373452
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6-[4-[1-[4-(5-chloro-1,3-benzothiazol-2-yl)piperazin-1-yl]-2-methyl-1-oxopropan-2-yl]oxyphenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C29H29ClN6O4S
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1
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| 1 |
Ki = 10000 nM
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CP0400044
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N-benzoyl-N-[4-(4-methoxyphenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C28H21N7O3
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1
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| 1 |
Ki > 10000 nM
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CP0493947
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N-benzoyl-N-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H18ClN7O2
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1
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| 1 |
Ki > 10000 nM
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CP0376876
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1-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-phenylurea
Show/Hide
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C19H16N6O
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1
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| 1 |
Ki > 10000 nM
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CP0376877
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N-(2-benzylpyrazolo[3,4-d]pyrimidin-4-yl)-4-methoxybenzamide
Show/Hide
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C20H17N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0383486
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1-(3-chlorophenyl)-3-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)urea
Show/Hide
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C19H15ClN6O
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1
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| 1 |
Ki > 10000 nM
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CP0383489
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1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-(4-methoxyphenyl)urea
Show/Hide
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C26H22N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0386423
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1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-phenylurea
Show/Hide
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C25H20N6O
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1
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| 1 |
Ki > 10000 nM
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CP0401447
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2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-amine
Show/Hide
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C12H11N5
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1
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| 1 |
Ki > 10000 nM
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CP0401450
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N-(2-benzyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)-4-methoxybenzamide
Show/Hide
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C26H21N5O2
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1
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| 1 |
Ki > 10000 nM
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CP0401451
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N-(2-benzylpyrazolo[3,4-d]pyrimidin-4-yl)benzamide
Show/Hide
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C19H15N5O
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1
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| 1 |
Ki > 10000 nM
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CP0421990
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1-(2-benzyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)-3-(3-chlorophenyl)urea
Show/Hide
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C25H19ClN6O
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1
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| 1 |
Ki > 10000 nM
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CP0421995
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N-(2-benzyl-6-phenylpyrazolo[3,4-d]pyrimidin-4-yl)-3-chlorobenzamide
Show/Hide
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C25H18ClN5O
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1
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| 1 |
Ki > 10000 nM
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CP0473074
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1-(3-chlorophenyl)-3-(2-phenethyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)urea
Show/Hide
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C26H21ClN6O
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1
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| 1 |
Ki > 10000 nM
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CP0479810
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1-(4-methoxyphenyl)-3-(2-phenethyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)urea
Show/Hide
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C27H24N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0479811
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1-(4-methoxyphenyl)-3-(2-methyl-6-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-yl)urea
Show/Hide
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C20H18N6O2
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1
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| 1 |
Ki > 10000 nM
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CP0460006
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N-[4-(4-bromophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C28H22BrN7O
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1
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| 1 |
Ki > 10000 nM
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CP0142536
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3,10-Diphenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
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C21H14N4O
|
1
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| 1 |
Ki > 10000 nM
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CP0378166
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3-phenyl-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
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C23H18N4O
|
1
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| 1 |
Ki > 10000 nM
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CP0399821
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10-Benzyl-3-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
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C22H16N4O
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1
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| 1 |
Ki > 10000 nM
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CP0416455
|
10-methyl-3-phenyl-10H-benzo[4,5]imidazo[2,1-c][1,2,4]triazin-4-one
Show/Hide
|
C16H12N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0416457
|
10-(4-chlorophenyl)-3-phenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C21H13ClN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0416922
|
7-chloro-3,10-diphenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C21H13ClN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0424403
|
7-chloro-3-(furan-2-yl)-10-phenyl-[1,2,4]triazino[4,3-a]benzimidazol-4-one
Show/Hide
|
C19H11ClN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0847642
|
3-phenyl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-one
Show/Hide
|
C15H10N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0433620
|
9-(1-adamantyl)-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
Show/Hide
|
C20H27N5O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489088
|
[4-(1,3-dimethyl-2,4-dioxo-6,7,8,9-tetrahydropurino[7,8-a][1,3]diazepin-10-yl)cyclohexyl] acetate
Show/Hide
|
C19H27N5O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375529
|
N-methyl-N-(4-oxo-3,1-benzothiazin-2-yl)-4-phenylbutanamide
Show/Hide
|
C19H18N2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0397156
|
N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methoxybenzamide
Show/Hide
|
C27H23N5O2S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0397157
|
4-methoxy-N-[4-phenyl-5-(pyridine-3-carbonyl)-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C23H17N3O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440163
|
N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]benzamide
Show/Hide
|
C26H21N5OS2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0465316
|
N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
|
C27H23N5OS2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375156
|
1-(1-benzylindol-3-yl)-2-(furan-2-yl)ethane-1,2-dione
Show/Hide
|
C21H15NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0375157
|
1-(1-benzylindol-3-yl)-2-phenylethane-1,2-dione
Show/Hide
|
C23H17NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0390547
|
2-(1-benzylindol-3-yl)-2-oxo-N-phenylacetamide
Show/Hide
|
C23H18N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0432902
|
N,1-dibenzylindole-3-carboxamide
Show/Hide
|
C23H20N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0461894
|
N-benzyl-2-(1-benzylindol-3-yl)-2-oxoacetamide
Show/Hide
|
C24H20N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0462184
|
1-benzyl-N-phenylindole-3-carboxamide
Show/Hide
|
C22H18N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0469201
|
1-(1-benzylindol-3-yl)-2-thiophen-2-ylethane-1,2-dione
Show/Hide
|
C21H15NO2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0379395
|
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-(dimethylamino)-2-(4-methylanilino)-1,3-thiazole-5-carboxamide
Show/Hide
|
C22H23N5OS2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0386845
|
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(4-methoxyanilino)-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H26N4O3S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0386847
|
ethyl 2-[[2-(4-methoxyanilino)-4-(4-methylphenyl)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
|
C29H29N3O4S2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0398409
|
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(4-methylanilino)-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H24N4OS2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0413121
|
US9326978, 32
Show/Hide
|
C22H22N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0414494
|
US9326978, 33
Show/Hide
|
C21H18Cl2N4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0414495
|
US9326978, 34
Show/Hide
|
C21H19ClN4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0408868
|
5-N,2-diphenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0405409
|
N-[5-amino-2-(furan-2-yl)-1,3-benzoxazol-7-yl]-2-piperidin-1-ylacetamide
Show/Hide
|
C18H20N4O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0457568
|
2-(furan-2-yl)-1,3-benzoxazol-5-amine
Show/Hide
|
C11H8N2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0494064
|
N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-3-[4-[4-(2-ethoxyethoxy)phenyl]piperazin-1-yl]propanamide
Show/Hide
|
C32H34N4O6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0529255
|
2-(furan-2-yl)-7-morpholin-4-yl-1,3-benzoxazol-5-amine
Show/Hide
|
C15H15N3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0536611
|
3-(3,4-dihydro-1H-isoquinolin-2-yl)-N-[7-(3,4-dimethoxyphenyl)-2-(furan-2-yl)-1,3-benzoxazol-5-yl]propanamide
Show/Hide
|
C31H29N3O5
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0561743
|
2-(furan-2-yl)-7-(4-methylphenyl)-1,3-benzoxazol-5-amine
Show/Hide
|
C18H14N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0572663
|
2-(furan-2-yl)-7-[4-(trifluoromethyl)phenyl]-1,3-benzoxazol-5-amine
Show/Hide
|
C18H11F3N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0542031
|
ethyl 2-(furan-2-yl)-5-pyrrolidin-1-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C16H17N5O3
|
1
|
| 1 |
Ki = 10200 nM
|
|
|
|
CP0454467
|
(2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C20H26ClN7O3
|
1
|
| 1 |
Ki = 10200 nM
|
|
|
|
CP0864683
|
(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(2-(4-chlorophenylamino)-4-methylthiazol-5-yl)methanone
Show/Hide
|
C21H18ClN5O2S
|
1
|
| 1 |
Ki = 10300 nM
|
|
|
|
CP0394476
|
2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylcarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
|
C18H25ClN6O5
|
1
|
| 1 |
Ki = 10400 nM
|
|
|
|
CP0421843
|
(2R,3R,4R,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-3,4-diol
Show/Hide
|
C16H23N5O4
|
1
|
| 1 |
Ki = 10400 nM
|
|
|
|
CP0342353
|
2-[(4-acetylphenyl)ethynyl]-N6-methoxy-5'-N-methylcarboxamidoadenosine
Show/Hide
|
C22H22N6O6
|
1
|
| 1 |
Ki = 10400 nM
|
|
|
|
CP0461206
|
(2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(methoxyamino)-2-((4-methoxyphenyl)ethynyl)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide
Show/Hide
|
C21H22N6O6
|
1
|
| 1 |
Ki = 10400 nM
|
|
|
|
CP0454469
|
(2S,3S,4R,5R)-2-(chloromethyl)-5-[6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C14H18ClN5O4
|
1
|
| 1 |
Ki = 10400 nM
|
|
|
|
CP0437163
|
(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)-2-(3,5-dimethylphenyl)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C30H37N7O3
|
1
|
| 1 |
Ki = 10500 nM
|
|
|
|
CP0496305
|
(2S,3S,4R,5R)-5-[6-Amino-2-(3-cyclopentyl-propionylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid ethylamide
Show/Hide
|
C20H29N7O5
|
1
|
| 1 |
Ki = 10800 nM
|
|
|
|
CP0228381
|
2-(6-Amino-purin-9-yl)-ethanol
Show/Hide
|
C7H9N5O
|
1
|
| 1 |
Ki = 11000 nM
|
|
|
|
CP0431050
|
9-Cycloheptyl-9H-adenine
Show/Hide
|
C12H17N5
|
1
|
| 1 |
Ki = 11000 nM
|
|
|
|
CP0446720
|
2-N-(4-chlorophenyl)-7-N,7-N-diethyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine
Show/Hide
|
C15H16ClN5S
|
1
|
| 1 |
Ki = 11200 nM
|
|
|
|
CP0869630
|
(2-amino-1-(4-chlorophenyl)-1H-imidazol-5-yl)(4-methyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
|
C20H16ClN5OS
|
1
|
| 1 |
Ki = 11200 nM
|
|
|
|
CP0450090
|
ethyl 6-[(4-fluorobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C16H14FN5O3
|
1
|
| 1 |
Ki = 11500 nM
|
|
|
|
CP0399695
|
2-Chloro-N6-(+/-)-endo-norbornyl-9H-(2-C-methyl-beta-D-ribofuranosyl)adenine
Show/Hide
|
C18H24ClN5O4
|
1
|
| 1 |
Ki = 11800 nM
|
|
|
|
CP0418071
|
ethyl 2-methyl-6-[(4-methylbenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C17H17N5O3
|
1
|
| 1 |
Ki = 11800 nM
|
|
|
|
CP0862331
|
N-(5-(2-amino-1-(4-chlorophenyl)-1H-imidazole-5-carbonyl)-4-(dimethylamino)thiazol-2-yl)benzamide
Show/Hide
|
C22H19ClN6O2S
|
1
|
| 1 |
Ki = 11800 nM
|
|
|
|
CP0454462
|
(2R,3R,4S,5R)-2-[2-chloro-6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C19H24ClN7O4
|
1
|
| 1 |
Ki = 11900 nM
|
|
|
|
CP0506270
|
7-Isopropyl-7H-adenine
Show/Hide
|
C8H11N5
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0395579
|
N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-4-methylbenzamide
Show/Hide
|
C14H12ClN5O
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0850611
|
N-phenethyl-9-propyl-9H-purin-6-amine
Show/Hide
|
C16H19N5
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0510605
|
6-[4-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-2-oxoethoxy]-2-methoxyphenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
|
C26H26N4O5
|
1
|
| 1 |
Ki = 12022.64 nM
|
|
|
|
CP0435875
|
(2S,3S,4R)-3,4-dihydroxy-5-((S)-2-iodo-6-methoxyamino-9H-purin-3-yl)-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
|
C12H15IN6O5
|
1
|
| 1 |
Ki = 12100 nM
|
|
|
|
CP0508141
|
7,8-dihydroxy-3-phenylchromen-2-one
Show/Hide
|
C15H10O4
|
1
|
| 1 |
Ki = 12100 nM
|
|
|
|
CP0657339
|
3-(4-bromothiophen-2-yl)-7,8-dihydroxy-2H-chromen-2-one
Show/Hide
|
C13H7BrO4S
|
1
|
| 1 |
Ki = 12200 nM
|
|
|
|
CP0453273
|
(2R,3S,4R)-2-hydroxymethyl-5-((S)-2-iodo-6-methoxyamino-9H-purin-3-yl)-tetrahydro-furan-3,4-diol
Show/Hide
|
C11H14IN5O5
|
1
|
| 1 |
Ki = 12400 nM
|
|
|
|
CP0375194
|
2-(furan-2-yl)-5-[(4-methoxyphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C18H15N5O4
|
1
|
| 1 |
Ki = 12400 nM
|
|
|
|
CP0852522
|
(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(4-methyl-2-(p-tolylamino)thiazol-5-yl)methanone
Show/Hide
|
C21H18FN5OS
|
1
|
| 1 |
Ki = 12400 nM
|
|
|
|
CP0399473
|
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-(2-pyridin-3-ylethynyl)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C18H18N6O5
|
1
|
| 1 |
Ki = 12500 nM
|
|
|
|
CP0088880
|
2-(4-Fluorophenyl)ethynyl-N6-methyl-5'-N-methylcarboxamidoadenosine
Show/Hide
|
C20H19FN6O4
|
1
|
| 1 |
Ki = 12700 nM
|
|
|
|
CP0870388
|
4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)-piperazin-1-ium chloride
Show/Hide
|
C15H17ClN8O
|
1
|
| 1 |
Ki = 12900 nM
|
|
|
|
CP0946757
|
N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine
Show/Hide
|
C17H21N5
|
1
|
| 1 |
Ki = 13000 nM
|
|
|
|
CP0862330
|
(2-amino-1-(4-fluorophenyl)-1H-imidazol-5-yl)(2-(4-chlorophenylamino)-4-methylthiazol-5-yl)methanone
Show/Hide
|
C20H15ClFN5OS
|
1
|
| 1 |
Ki = 13000 nM
|
|
|
|
CP0445853
|
N-(4-chlorophenyl)-7-piperidin-1-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
|
C16H16ClN5S
|
1
|
| 1 |
Ki = 13200 nM
|
|
|
|
CP0857113
|
(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(4-methyl-2-(phenylamino)thiazol-5-yl)methanone
Show/Hide
|
C21H19N5O2S
|
1
|
| 1 |
Ki = 13400 nM
|
|
|
|
CP0408741
|
N-cyclohexyl-2-phenylsulfanyl-7H-purin-6-amine
Show/Hide
|
C17H19N5S
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0455153
|
3-(3,4-dihydroxyphenyl)-8-hydroxychromen-2-one
Show/Hide
|
C15H10O5
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0396639
|
N-[5-(4-amino-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
|
C24H19N5O2S2
|
1
|
| 1 |
Ki = 14400 nM
|
|
|
|
CP0552686
|
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C20H27N7O3
|
1
|
| 1 |
Ki = 14500 nM
|
|
|
|
CP0446164
|
(2S,3S,4R,5R)-3,4-dihydroxy-5-[6-(methoxyamino)-2-[2-(4-methylphenyl)ethynyl]purin-9-yl]-N-methyloxolane-2-carboxamide
Show/Hide
|
C21H22N6O5
|
1
|
| 1 |
Ki = 14700 nM
|
|
|
|
CP0756037
|
8-Acetoxy-3-(thiophen-3-yl)coumarin
Show/Hide
|
C15H10O4S
|
1
|
| 1 |
Ki = 14700 nM
|
|
|
|
CP0922130
|
7,8-dihydroxy-3-(thiophen-3-yl)-2H-chromen-2-one
Show/Hide
|
C13H8O4S
|
1
|
| 1 |
Ki = 14700 nM
|
|
|
|
CP0436903
|
N-[2-[4-(8-amino-3-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-6-yl)phenoxy]ethyl]-3,5-ditert-butyl-4-hydroxybenzamide
Show/Hide
|
C34H38N6O4
|
1
|
| 1 |
Ki = 14750 nM
|
|
|
|
CP0381898
|
8-Bromo-9-cyclohexyl-9H-adenine
Show/Hide
|
C11H14BrN5
|
1
|
| 1 |
Ki = 15000 nM
|
|
|
|
CP0418075
|
6-amino-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxamide
Show/Hide
|
C14H14N6O
|
1
|
| 1 |
Ki = 15700 nM
|
|
|
|
CP0417215
|
2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl-5-N-methylthiocarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
|
C17H23ClN6O5S
|
1
|
| 1 |
Ki = 15900 nM
|
|
|
|
CP0378155
|
N-cyclohexyl-2-phenoxy-7H-purin-6-amine
Show/Hide
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C17H19N5O
|
1
|
| 1 |
Ki = 16000 nM
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|
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CP0374423
|
9-(sec-Butyl)-9H-adenine
Show/Hide
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C9H13N5
|
1
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| 1 |
Ki = 16000 nM
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CP0418069
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ethyl 6-benzamido-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C16H15N5O3
|
1
|
| 1 |
Ki = 16100 nM
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|
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CP0420985
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8-(2-oxopropoxy)-3-phenylchromen-2-one
Show/Hide
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C18H14O4
|
1
|
| 1 |
Ki = 16100 nM
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CP0503246
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2-Chloro-N6-cyclopentyl-9H-(2-C-methyl-5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
Show/Hide
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C16H21Cl2N5O3
|
1
|
| 1 |
Ki = 16200 nM
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CP0336395
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(2S,3S,4R)-3,4-dihydroxy-5-((R)-6-methoxyamino-2-phenylethynyl-9H-purin-3-yl)-tetrahydro-furan-2-carboxylic acid methylamide
Show/Hide
|
C20H20N6O5
|
1
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| 1 |
Ki = 16300 nM
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|
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CP0435769
|
N-[4-chloro-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C21H15ClF3N5O
|
1
|
| 1 |
Ki = 16400 nM
|
|
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CP0864681
|
N-(5-(2-amino-1-(4-(trifluoromethyl)phenyl)-1H-imidazole-5-carbonyl)-4-(dimethylamino)thiazol-2-yl)benzamide
Show/Hide
|
C23H19F3N6O2S
|
1
|
| 1 |
Ki = 16700 nM
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CP0395638
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N-benzoyl-N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
|
C20H14ClN5O2
|
1
|
| 1 |
Ki = 17500 nM
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CP0396839
|
ethyl 2-(furan-2-yl)-5-morpholin-4-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
|
C16H17N5O4
|
1
|
| 1 |
Ki = 17600 nM
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|
|
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CP0226002
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(2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(methoxyamino)-2-(pyridin-2-ylethynyl)-9H-purin-9-yl)-N-methyltetrahydrofuran-2-carboxamide
Show/Hide
|
C19H19N7O5
|
1
|
| 1 |
Ki = 18000 nM
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|
|
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CP0467847
|
7-Propyl-7H-adenine
Show/Hide
|
C8H11N5
|
1
|
| 1 |
Ki = 18000 nM
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CP0508102
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2-(furan-2-yl)-5-[[4-(trifluoromethyl)phenyl]methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C18H12F3N5O3
|
1
|
| 1 |
Ki = 18000 nM
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CP0398412
|
ethyl 2-[[4-(dimethylamino)-2-(4-methylanilino)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
|
C24H28N4O3S2
|
1
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| 1 |
Ki = 18000 nM
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CP0276322
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(2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(methoxyamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide
Show/Hide
|
C20H19FN6O5
|
1
|
| 1 |
Ki = 18700 nM
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|
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CP0758153
|
8-Acetoxy-3-(thiophen-2-yl)coumarin
Show/Hide
|
C15H10O4S
|
1
|
| 1 |
Ki = 18800 nM
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|
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CP0399694
|
(2S,3S,4R,5R)-2-[(2-fluorophenyl)sulfanylmethyl]-5-[6-(oxolan-3-ylamino)purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C20H22FN5O4S
|
1
|
| 1 |
Ki = 18900 nM
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|
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CP0848773
|
trans-9-(4-hydroxycyclohexyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-f]purine-2,4(1H,3H)-dione
Show/Hide
|
C16H23N5O3
|
1
|
| 1 |
Ki = 19000 nM
|
|
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CP0452425
|
N-[4-(4-chlorophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
|
C27H20ClN7O
|
1
|
| 1 |
Ki = 19400 nM
|
|
|
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CP0437166
|
(2R,3R,4S,5R)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
|
C22H29N7O3
|
1
|
| 1 |
Ki = 19600 nM
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|
|
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CP0442956
|
N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-4-fluorobenzamide
Show/Hide
|
C13H9ClFN5O
|
1
|
| 1 |
Ki = 20500 nM
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|
|
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CP0730941
|
2-oxo-3-(thiophen-3-yl)-2H-chromene-7,8-diyl diacetate
Show/Hide
|
C17H12O6S
|
1
|
| 1 |
Ki = 20600 nM
|
|
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CP0439928
|
(8-acetyloxy-2-oxo-3-phenylchromen-7-yl) acetate
Show/Hide
|
C19H14O6
|
1
|
| 1 |
Ki = 21100 nM
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|
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CP0902320
|
4-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo-[1,5-c]pyrimidin-5-yl)piperazine-1-carboxylic acid tert-butyl ester
Show/Hide
|
C20H24N8O3
|
1
|
| 1 |
Ki = 21400 nM
|
|
|
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CP0376574
|
CHEMBL2153622
Show/Hide
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C18H25N5O4
|
1
|
| 1 |
Ki = 21900 nM
|
|
|
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CP0472360
|
N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-(dimethylamino)-2-(4-methylanilino)-1,3-thiazole-5-carboxamide
Show/Hide
|
C22H25N5O2S2
|
1
|
| 1 |
Ki = 22300 nM
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|
|
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CP0902367
|
N-benzyl-9-propyl-9H-purin-6-amine
Show/Hide
|
C15H17N5
|
1
|
| 1 |
Ki = 22600 nM
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|
|
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CP0386798
|
2-(furan-2-yl)-5-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C17H20N6O5
|
1
|
| 1 |
Ki = 22600 nM
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|
|
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CP0043620
|
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Show/Hide
|
C8H10N4O2
|
1
|
| 1 |
Ki = 23400 nM
|
|
|
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CP0395581
|
N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-2-phenylacetamide
Show/Hide
|
C18H20ClN5O
|
1
|
| 1 |
Ki = 23600 nM
|
|
|
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CP0495890
|
N-[11-methyl-4-(4-nitrophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
|
C21H16N8O3
|
1
|
| 1 |
Ki = 23900 nM
|
|
|
|
CP0485049
|
(2R,3R,4R,5S)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-(chloromethyl)-3-methyloxolane-3,4-diol
Show/Hide
|
C18H24ClN5O3
|
1
|
| 1 |
Ki = 24000 nM
|
|
|
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CP0395578
|
N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)benzamide
Show/Hide
|
C13H10ClN5O
|
1
|
| 1 |
Ki = 24200 nM
|
|
|
|
CP0335818
|
2-(2-Pyridinyl)ethynyl-N6-methyl-5'-N-methylcarboxamidoadenosine
Show/Hide
|
C19H19N7O4
|
1
|
| 1 |
Ki = 24300 nM
|
|
|
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CP0487929
|
5-(cyclohexylcarbamoylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C17H18N6O4
|
1
|
| 1 |
Ki = 24700 nM
|
|
|
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CP0452426
|
N-[4-(4-methoxyphenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
|
C28H23N7O2
|
1
|
| 1 |
Ki = 25200 nM
|
|
|
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CP0478861
|
3-(3,4-dihydroxyphenyl)-7,8-dihydroxychromen-2-one
Show/Hide
|
C15H10O6
|
1
|
| 1 |
Ki = 25500 nM
|
|
|
|
CP0395635
|
N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-4-(trifluoromethyl)benzamide
Show/Hide
|
C14H9ClF3N5O
|
1
|
| 1 |
Ki = 25600 nM
|
|
|
|
CP0415060
|
1,3-Dibenzyl-1H-1,3,4b,9-tetraaza-fluorene-2,4-dione
Show/Hide
|
C23H18N4O2
|
1
|
| 1 |
Ki = 25800 nM
|
|
|
|
CP0533579
|
3-(3,4-dimethoxyphenyl)-8-methylchromen-2-one
Show/Hide
|
C18H16O4
|
1
|
| 1 |
Ki = 25900 nM
|
|
|
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CP0379397
|
4-O-ethyl 2-O-methyl 5-[[4-(dimethylamino)-2-(4-methylanilino)-1,3-thiazole-5-carbonyl]amino]-3-methylthiophene-2,4-dicarboxylate
Show/Hide
|
C23H26N4O5S2
|
1
|
| 1 |
Ki = 26600 nM
|
|
|
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CP0379815
|
2-(furan-2-yl)-5-(pentylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
|
C15H17N5O3
|
1
|
| 1 |
Ki = 26900 nM
|
|
|
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CP0446154
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-[6-(methoxyamino)-2-[2-(4-pentylphenyl)ethynyl]purin-9-yl]oxolane-2-carboxamide
Show/Hide
|
C26H32N6O5
|
1
|
| 1 |
Ki = 27100 nM
|
|
|
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CP0472359
|
ethyl 2-[[2-anilino-4-(4-methylphenyl)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
|
C28H27N3O3S2
|
1
|
| 1 |
Ki = 28400 nM
|
|
|
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CP0454463
|
(2R,3S,4R,5R)-2-[(3,5-dimethylpyrazol-1-yl)methyl]-5-[6-[[(3R)-oxolan-3-yl]amino]purin-9-yl]oxolane-3,4-diol
Show/Hide
|
C19H25N7O4
|
1
|
| 1 |
Ki = 28600 nM
|
|
|
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CP0379873
|
7-chloro-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
|
C11H7ClN6O
|
1
|
| 1 |
Ki = 29900 nM
|
|
|
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CP0395580
|
N-(4-chloro-2-methylpyrazolo[3,4-d]pyrimidin-6-yl)-2-phenylacetamide
Show/Hide
|
C14H12ClN5O
|
1
|
| 1 |
Ki = 29900 nM
|
|
|
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CP0374393
|
7-Ethyl-7H-adenine
Show/Hide
|
C7H9N5
|
1
|
| 1 |
Ki = 30000 nM
|
|
|
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CP0372973
|
2-(4-Bromophenyl)-8-phenylethylpyrazolo[4,3-e]1,2,4-triazolo-[1,5-c]pyrimidin-5-amine
Show/Hide
|
C20H16BrN7
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0390097
|
11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C19H15N7
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0440625
|
1-(4-fluorophenyl)-3-[11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
|
C21H14F4N8O
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0486048
|
1-[11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
|
C26H20N8O
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0388103
|
4-(furan-2-yl)-7-methoxy-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaene
Show/Hide
|
C12H10N6O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0391355
|
4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,9-tetraen-7-one
Show/Hide
|
C11H8N6O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0397425
|
N-(1-adamantyl)-4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-amine
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0380971
|
N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methoxybenzamide
Show/Hide
|
C25H21N5O2S2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0489123
|
N-[5-(4-amino-5,6-dimethylthieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
Show/Hide
|
C25H21N5OS2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0386846
|
ethyl 2-[[2-(4-methylanilino)-4-(4-methylphenyl)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
|
C29H29N3O3S2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0398410
|
N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-(4-methoxyanilino)-4-(4-methylphenyl)-1,3-thiazole-5-carboxamide
Show/Hide
|
C27H24N4O2S2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0398411
|
ethyl 2-[[4-methyl-2-(4-methylanilino)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
|
C23H25N3O3S2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0418719
|
2-anilino-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-4-(dimethylamino)-1,3-thiazole-5-carboxamide
Show/Hide
|
C21H21N5OS2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0487741
|
4-O-ethyl 2-O-methyl 3-methyl-5-[[4-methyl-2-(4-methylanilino)-1,3-thiazole-5-carbonyl]amino]thiophene-2,4-dicarboxylate
Show/Hide
|
C22H23N3O5S2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0424461
|
7-chloro-N-(4-nitrophenyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
|
C11H6ClN5O2S
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0432532
|
6-(4-methylphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C18H14N4O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0447254
|
8-amino-2-phenyl-6-(3-phenylmethoxyphenyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C24H19N5O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0447255
|
2-(2-hydroxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C17H12N4O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0447256
|
6-(4-methoxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C18H14N4O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0448678
|
2-(2-methoxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C18H14N4O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0448679
|
2-(4-methoxyphenyl)-6-methyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C13H12N4O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0456470
|
2-(4-methoxyphenyl)-6-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C18H14N4O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0458429
|
2,6-diphenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C17H12N4O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0458575
|
8-amino-6-(4-methylphenyl)-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C18H15N5O
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0472716
|
6-(4-hydroxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C17H12N4O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0479664
|
8-amino-6-[4-(cyclobutylmethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C22H21N5O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0479669
|
6-methyl-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
Show/Hide
|
C12H10N4O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0492103
|
8-amino-6-[4-(cyclopropylmethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0533476
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6-(3-methoxyphenyl)-2-phenyl-7H-[1,2,4]triazolo[4,3-a]pyrazine-3,8-dione
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C18H14N4O3
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1
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| 1 |
Ki > 30000 nM
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CP0386797
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ethyl 2-(furan-2-yl)-5-piperazin-1-yl-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C16H18N6O3
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1
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| 1 |
Ki > 30000 nM
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CP0427863
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4-methoxy-N-(5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
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C20H16N4O2S
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1
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| 1 |
Ki > 30000 nM
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CP0517715
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4-chloro-N-(5-methyl-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidin-7-yl)benzamide
Show/Hide
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C19H13ClN4OS
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1
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| 1 |
Ki > 30000 nM
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CP0567585
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8-amino-6-[4-(2-chloroethoxy)phenyl]-2-phenyl-[1,2,4]triazolo[4,3-a]pyrazin-3-one
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C19H16ClN5O2
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1
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| 1 |
Ki > 30000 nM
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CP0417325
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-(2-C-methyl-5-chloro-5-deoxy-beta-D-ribofuranosyl)adenine
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C18H23Cl2N5O3
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1
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| 1 |
Ki = 31600 nM
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CP0437022
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(2S,3S,4R,5R)-3,4-dihydroxy-5-[6-(methoxyamino)-2-[2-(4-pentylphenyl)ethynyl]purin-9-yl]-N-methyloxolane-2-carboxamide
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C25H30N6O5
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1
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| 1 |
Ki = 31700 nM
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CP0475489
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8-methyl-3-(3,4,5-trimethoxyphenyl)chromen-2-one
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C19H18O5
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1
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| 1 |
Ki = 32900 nM
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CP0379840
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5-(2-ethylhexylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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C18H23N5O3
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1
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| 1 |
Ki = 33800 nM
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CP0396846
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5-(cyclohexylmethylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
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C17H19N5O3
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1
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| 1 |
Ki = 33900 nM
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CP0864687
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(2-amino-1-p-tolyl-1H-imidazol-5-yl)(2-morpholino-4-phenylthiazol-5-yl)methanone
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C24H23N5O2S
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1
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| 1 |
Ki = 34000 nM
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CP0483813
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(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methoxyamino)-2-[2-(4-methylphenyl)ethynyl]purin-9-yl]oxolane-3,4-diol
Show/Hide
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C20H21N5O5
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1
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| 1 |
Ki = 35100 nM
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CP0420986
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(2-oxo-3-phenylchromen-8-yl) acetate
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C17H12O4
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1
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| 1 |
Ki = 35700 nM
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CP0390259
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1-[11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-phenylurea
Show/Hide
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C21H15F3N8O
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1
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| 1 |
Ki = 36000 nM
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CP0521358
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2-(3-cyclopropyl-4-oxo-7-phenylpyrrolo[3,2-d]pyrimidin-5-yl)-N-[(4-fluorophenyl)methyl]acetamide
Show/Hide
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C24H21FN4O2
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1
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| 1 |
Ki = 36307.81 nM
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CP0419830
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5-(cyclopentylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C15H15N5O3
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1
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| 1 |
Ki = 37300 nM
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CP0384080
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2-amino-4-(3-bromophenyl)-6-(4-methoxyphenyl)pyridine-3-carbonitrile
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C19H14BrN3O
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1
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| 1 |
Ki = 38018.94 nM
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CP0378173
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6-N-(2-bicyclo[2.2.1]heptanyl)-2-N-(4-morpholin-4-ylphenyl)-7H-purine-2,6-diamine
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C22H27N7O
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1
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| 1 |
Ki = 39000 nM
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CP0294742
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(2S,3S,4R,5R)-3,4-dihydroxy-N-methyl-5-[6-(methylamino)-2-(2-phenylethynyl)purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C20H20N6O4
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1
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| 1 |
Ki = 41700 nM
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CP0420989
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8-methyl-3-phenylchromen-2-one
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C16H12O2
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1
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| 1 |
Ki = 42100 nM
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CP0262712
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8-Hydroxy-3-phenylcoumarin
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C15H10O3
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1
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| 1 |
Ki = 42300 nM
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CP0411867
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ethyl 2-(furan-2-yl)-5-[(2-phenylacetyl)amino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C20H17N5O4
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1
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| 1 |
Ki = 42700 nM
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CP0466904
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6-N-cyclooctyl-2-N-phenyl-7H-purine-2,6-diamine
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C19H24N6
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1
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| 1 |
Ki = 46000 nM
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CP0887833
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(E)-3-[6-Amino-9-((3S,4R,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-8-yl]-1-phenyl-propenone
Show/Hide
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C19H19N5O5
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1
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| 1 |
Ki = 46600 nM
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CP0251309
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8-Ethoxy-3-phenylcoumarin
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C17H14O3
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1
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| 1 |
Ki = 55000 nM
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CP0533580
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7,8-dihydroxy-3-(4-hydroxyphenyl)chromen-2-one
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C15H10O5
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1
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| 1 |
Ki = 55300 nM
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CP0478849
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8-methoxy-3-(4-nitrophenyl)chromen-2-one
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C16H11NO5
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1
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| 1 |
Ki = 59100 nM
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CP0470627
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8-ethoxy-3-(4-methylphenyl)chromen-2-one
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C18H16O3
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1
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| 1 |
Ki > 60000 nM
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CP0491850
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[2-acetyloxy-4-(8-acetyloxy-2-oxochromen-3-yl)phenyl] acetate
Show/Hide
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C21H16O8
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1
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| 1 |
Ki = 64400 nM
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CP0446051
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6-amino-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidine-4-carboxamide
Show/Hide
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C11H16N6O
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1
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| 1 |
Ki > 80000 nM
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CP0849991
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(2R,3R,4S,5R)-2-(6-amino-8-(hex-1-ynyl)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Show/Hide
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C16H21N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0885586
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8-(2-phenylethynyl)adenosine
Show/Hide
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C18H17N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0424788
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2'-Me-tecadenoson
Show/Hide
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C15H21N5O5
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1
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| 1 |
Ki > 100000 nM
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CP0446517
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2-chloro-N6-(R)-3-tetrahydrofuranyl-9H-(2-C-methyl-5-N-methylcarbamoyl-beta-D-ribofuranosyl)adenine
Show/Hide
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C17H23ClN6O6
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1
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| 1 |
Ki > 100000 nM
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CP0449107
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2-chloro-2'-C-methyl-tecadenoson
Show/Hide
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C15H20ClN5O5
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1
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| 1 |
Ki > 100000 nM
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CP0381891
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7-(3-Hydroxypropyl)-7H-adenine
Show/Hide
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C8H11N5O
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1
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| 1 |
Ki > 100000 nM
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CP0381893
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7-Methyl-7H-adenine
Show/Hide
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C6H7N5
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1
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| 1 |
Ki > 100000 nM
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CP0381895
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9-Isobutyl-9H-adenine
Show/Hide
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C9H13N5
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1
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| 1 |
Ki > 100000 nM
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CP0381897
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9-Cyclohexyl-9H-adenine
Show/Hide
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C11H15N5
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1
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| 1 |
Ki > 100000 nM
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CP0386727
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7-(sec-Butyl)-7H-adenine
Show/Hide
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C9H13N5
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1
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| 1 |
Ki > 100000 nM
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CP0399763
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7-(2-Hydroxyethyl)-7H-adenine
Show/Hide
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C7H9N5O
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1
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| 1 |
Ki > 100000 nM
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CP0399764
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7-(2,3-Dihydroxypropyl)-7H-adenine
Show/Hide
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C8H11N5O2
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1
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| 1 |
Ki > 100000 nM
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CP0417368
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7-(2-Hydroxypropyl)-7H-adenine
Show/Hide
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C8H11N5O
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1
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| 1 |
Ki > 100000 nM
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CP0417372
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7-Isobutyl-7H-adenine
Show/Hide
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C9H13N5
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1
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| 1 |
Ki > 100000 nM
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CP0439344
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8-Bromo-9-cycloheptyl-9H-adenine
Show/Hide
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C12H16BrN5
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1
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| 1 |
Ki > 100000 nM
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CP0399698
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2-Chloro-N6-cyclopentyl-9H-[2-C-methyl-5-deoxy-5-(2-fluorophenylthio)-beta-D-ribofuranosyl]adenine
Show/Hide
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C22H25ClFN5O3S
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1
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| 1 |
Ki > 100000 nM
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CP0415649
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2-Chloro-N6-(+/-)-endo-norbornyl-9H-[2-C-methyl-5-deoxy-5-(2-fluorophenylthio)-beta-D-ribofuranosyl]adenine
Show/Hide
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C24H27ClFN5O3S
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1
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| 1 |
Ki > 100000 nM
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CP0491862
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(2R,3R,4R,5S)-2-[6-(cyclopentylamino)purin-9-yl]-5-[(2-fluorophenyl)sulfanylmethyl]-3-methyloxolane-3,4-diol
Show/Hide
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C22H26FN5O3S
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1
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| 1 |
Ki > 100000 nM
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CP0491866
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(2R,3R,4R,5S)-2-[6-(2-bicyclo[2.2.1]heptanylamino)purin-9-yl]-5-[(2-fluorophenyl)sulfanylmethyl]-3-methyloxolane-3,4-diol
Show/Hide
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C24H28FN5O3S
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1
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| 1 |
Ki > 100000 nM
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CP0510001
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(2R,3R,4R,5S)-5-(chloromethyl)-2-[6-(cyclopentylamino)purin-9-yl]-3-methyloxolane-3,4-diol
Show/Hide
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C16H22ClN5O3
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1
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| 1 |
Ki > 100000 nM
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CP0400008
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N-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C21H16BrN7O
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1
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| 1 |
Ki > 100000 nM
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CP0400043
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N-[11-methyl-4-(4-nitrophenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14N8O3
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1
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| 1 |
Ki > 100000 nM
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CP0493941
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N-[4-(4-bromophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14BrN7O
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1
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| 1 |
Ki > 100000 nM
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CP0502326
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N-[4-(4-bromophenyl)-11-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C27H20BrN7O
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1
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| 1 |
Ki > 100000 nM
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CP0504230
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N-[4-(4-chlorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14ClN7O
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1
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| 1 |
Ki > 100000 nM
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CP0504275
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N-[4-(4-methoxyphenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2-phenylacetamide
Show/Hide
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C22H19N7O2
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1
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| 1 |
Ki > 100000 nM
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CP0507716
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N-[4-(4-methoxyphenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C21H17N7O2
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1
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| 1 |
Ki > 100000 nM
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CP0514610
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N-[4-(4-fluorophenyl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]benzamide
Show/Hide
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C20H14FN7O
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1
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| 1 |
Ki > 100000 nM
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CP0390264
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1-(4-methoxyphenyl)-3-[11-methyl-4-[4-(trifluoromethyl)phenyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C22H17F3N8O2
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1
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| 1 |
Ki > 100000 nM
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CP0440626
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1-(4-fluorophenyl)-3-[11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C26H19FN8O
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1
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| 1 |
Ki > 100000 nM
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CP0486047
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1-(4-methoxyphenyl)-3-[11-methyl-4-(4-phenylphenyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C27H22N8O2
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1
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| 1 |
Ki > 100000 nM
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CP0465317
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N-[5-(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)-4-phenyl-1,3-thiazol-2-yl]furan-2-carboxamide
Show/Hide
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C22H16N4O3S2
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1
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| 1 |
Ki > 100000 nM
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CP0387954
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ethyl 2-(2,2-dimethylpropyl)-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C21H22F3N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0395577
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N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]-4-(trifluoromethyl)benzamide
Show/Hide
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C18H17ClF3N5O
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1
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| 1 |
Ki > 100000 nM
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CP0396085
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ethyl 2-(2,2-dimethylpropyl)-6-[(4-methylbenzoyl)amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C21H25N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0415742
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N-benzoyl-N-[4-chloro-2-(2,2-dimethylpropyl)pyrazolo[3,4-d]pyrimidin-6-yl]benzamide
Show/Hide
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C24H22ClN5O2
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1
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| 1 |
Ki > 100000 nM
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CP0379819
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5-[(4-chlorophenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C17H12ClN5O3
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1
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| 1 |
Ki > 100000 nM
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CP0379836
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5-(benzhydrylamino)-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C23H17N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0397027
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2-(furan-2-yl)-5-[(4-phenylphenyl)methylamino]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C23H17N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0414534
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ethyl 2-(furan-2-yl)-5-(morpholin-4-ylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
Show/Hide
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C16H18N6O4
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1
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| 1 |
Ki > 100000 nM
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CP0419805
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2-(furan-2-yl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylic acid
Show/Hide
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C11H9N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0429152
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ethyl 2-[[2-(acetyloxyamino)-4-(dimethylamino)-1,3-thiazole-5-carbonyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
Show/Hide
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C19H24N4O5S2
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1
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| 1 |
Ki > 100000 nM
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CP0380638
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ethyl 6-(dibenzoylamino)-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C30H25N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0386784
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ethyl 6-[(3,4-dichlorobenzoyl)amino]-2-(2-phenylethyl)pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H19Cl2N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0395503
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ethyl 6-[bis(3,4-difluorobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H15F4N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0418070
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ethyl 2-methyl-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C17H14F3N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0418076
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ethyl 6-[bis(4-bromobenzoyl)amino]-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H17Br2N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0448365
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ethyl 6-(dibenzoylamino)-2-propan-2-ylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C25H23N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0459772
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ethyl 2-propan-2-yl-6-[[4-(trifluoromethyl)benzoyl]amino]pyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
|
C19H18F3N5O3
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1
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| 1 |
Ki > 100000 nM
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CP0480605
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ethyl 6-(dibenzoylamino)-2-methylpyrazolo[3,4-d]pyrimidine-4-carboxylate
Show/Hide
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C23H19N5O4
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1
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| 1 |
Ki > 100000 nM
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CP0756382
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8-Acetoxy-3-(4-bromothiophen-2-yl)coumarin
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C15H9BrO4S
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1
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| 1 |
Ki > 100000 nM
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CP0799799
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3-(4-Bromothiophen-2-yl)-8-hydroxycoumarin
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C13H7BrO3S
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1
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| 1 |
Ki > 100000 nM
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CP0801197
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7,8-Diacetoxy-3-(thiophen-2-yl)coumarin
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C17H12O6S
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1
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| 1 |
Ki > 100000 nM
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CP0890934
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3-(4-bromothiophen-2-yl)-2-oxo-2H-chromene-7,8-diyl diacetate
Show/Hide
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C17H11BrO6S
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1
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| 1 |
Ki > 100000 nM
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CP0415543
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N-(4-chlorophenyl)-7-(4-methylpiperazin-1-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
Show/Hide
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C16H17ClN6S
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1
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| 1 |
Ki > 100000 nM
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CP0424362
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2-N-(4-chlorophenyl)-7-N,7-N-dimethyl-[1,3]thiazolo[5,4-d]pyrimidine-2,7-diamine
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C13H12ClN5S
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1
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| 1 |
Ki > 100000 nM
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CP0424460
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7-chloro-N-(2-morpholin-4-ylethyl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C11H14ClN5OS
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1
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| 1 |
Ki > 100000 nM
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CP0445858
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N-phenyl-7-(4-piperidin-1-ylpiperidin-1-yl)-[1,3]thiazolo[5,4-d]pyrimidin-2-amine
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C21H26N6S
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1
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| 1 |
Ki > 100000 nM
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CP0437159
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(2R,3R,4S,5R)-2-[2-chloro-6-(4-chloro-2-fluoroanilino)purin-9-yl]-5-[(3,5-dimethylpyrazol-1-yl)methyl]oxolane-3,4-diol
Show/Hide
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C21H20Cl2FN7O3
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1
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| 1 |
Ki > 100000 nM
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CP0393010
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4-[6-(cyclopentylamino)-9-methylpurin-8-yl]benzoic acid
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C18H19N5O2
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1
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| 1 |
Ki > 100000 nM
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CP0864685
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(2-amino-1-(4-methoxyphenyl)-1H-imidazol-5-yl)(2-morpholino-4-phenylthiazol-5-yl)methanone
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C24H23N5O3S
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1
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| 1 |
Ki > 100000 nM
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CP0394646
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ethyl 2-(furan-2-yl)-5-[4-[(2-methylpropan-2-yl)oxycarbonyl]piperazin-1-yl]-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxylate
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C21H26N6O5
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1
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| 1 |
Ki > 100000 nM
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CP0262711
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8-Ethoxy-3-(4'-methoxyphenyl)coumarin
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C18H16O4
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1
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| 1 |
Ki > 100000 nM
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CP0286485
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8-methoxy-3-(4-methoxyphenyl)chromen-2-one
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C17H14O4
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1
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| 1 |
Ki > 100000 nM
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CP0420984
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3-(4-methylphenyl)-8-(2-oxopropoxy)chromen-2-one
Show/Hide
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C19H16O4
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1
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| 1 |
Ki > 100000 nM
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CP0420987
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3-(4-bromophenyl)-8-hydroxychromen-2-one
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C15H9BrO3
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1
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| 1 |
Ki > 100000 nM
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CP0420988
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3-(4-bromophenyl)-8-ethoxychromen-2-one
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C17H13BrO3
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1
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| 1 |
Ki > 100000 nM
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CP0439927
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8-methyl-3-(3,4,5-trihydroxyphenyl)chromen-2-one
Show/Hide
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C16H12O5
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1
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| 1 |
Ki > 100000 nM
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CP0443765
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8-methyl-3-(4-nitrophenyl)chromen-2-one
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C16H11NO4
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1
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| 1 |
Ki > 100000 nM
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CP0455154
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3-(2,4-dimethoxyphenyl)-8-ethoxychromen-2-one
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C19H18O5
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1
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| 1 |
Ki > 100000 nM
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CP0470628
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8-methyl-3-(4-methylphenyl)chromen-2-one
Show/Hide
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C17H14O2
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1
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| 1 |
Ki > 100000 nM
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CP0475490
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3-(3,4-dimethoxyphenyl)-8-ethoxychromen-2-one
Show/Hide
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C19H18O5
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1
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| 1 |
Ki > 100000 nM
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CP0477026
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3-(4-bromophenyl)-8-(2-oxopropoxy)chromen-2-one
Show/Hide
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C18H13BrO4
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1
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| 1 |
Ki > 100000 nM
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CP0477027
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8-ethoxy-3-(3,4,5-trimethoxyphenyl)chromen-2-one
Show/Hide
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C20H20O6
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1
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| 1 |
Ki > 100000 nM
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CP0477468
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[2-acetyloxy-4-(7,8-diacetyloxy-2-oxochromen-3-yl)phenyl] acetate
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C23H18O10
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1
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| 1 |
Ki > 100000 nM
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CP0482593
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8-ethoxy-3-(4-nitrophenyl)chromen-2-one
Show/Hide
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C17H13NO5
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1
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| 1 |
Ki > 100000 nM
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CP0508140
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[4-(7,8-diacetyloxy-2-oxochromen-3-yl)phenyl] acetate
Show/Hide
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C21H16O8
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1
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| 1 |
Ki > 100000 nM
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CP0468872
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5-(4-chlorophenyl)-2-pyrrolidin-1-yl-3H-pyrido[2,3-d]pyrimidin-4-one
Show/Hide
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C17H15ClN4O
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1
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| 1 |
Ki > 100000 nM
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CP0478441
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N-cyclopentyl-5-methyl-3-[(4-methylbenzoyl)amino]-1H-indole-2-carboxamide
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C23H25N3O2
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1
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| 1 |
Ki > 100000 nM
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CP0483161
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2-amino-4-(1,3-benzodioxol-5-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
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C17H15N3O2
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1
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| 1 |
Ki > 100000 nM
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CP0548760
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3-prop-2-enyl-2-(pyridin-2-ylmethylsulfanyl)-5H-pyrimido[5,4-b]indol-4-one
Show/Hide
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C19H16N4OS
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1
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| 1 |
Ki > 100000 nM
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CP0380869
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1,3-dimethyl-8-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]-7H-purine-2,6-dione
Show/Hide
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C21H27N5O4
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1
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| 1 |
Ki > 10 nM
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CP0395277
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8-[[4-(3-chloropropoxy)phenyl]methyl]-1,3-dimethyl-7H-purine-2,6-dione
Show/Hide
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C17H19ClN4O3
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1
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| 1 |
Ki > 10 nM
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CP0376352
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2-(5-Morpholin-4-ylmethyl-furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C23H24N8O2
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1
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| 1 |
Ki > 1000 nM
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CP0480975
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2-[5-(4-Methyl-piperazin-1-ylmethyl)-furan-2-yl]-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C24H27N9O
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1
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| 1 |
Ki > 1000 nM
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CP0376396
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8-Methyl-2-[5-(4-methyl-piperazin-1-ylmethyl)-furan-2-yl]-9-methylsulfanyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C18H23N9OS
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1
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| 1 |
Ki > 1000 nM
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CP0384189
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4-(5-Amino-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-phenol
Show/Hide
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C20H17N7O
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1
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| 1 |
Ki > 1000 nM
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CP0394380
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4-(5-Amino-2-furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-9-ylamino)-phenol
Show/Hide
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C17H14N8O2
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1
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| 1 |
Ki > 1000 nM
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CP0401422
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2-Furan-2-yl-N*9*-(4-methoxy-phenyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine-5,9-diamine
Show/Hide
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C18H16N8O2
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1
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| 1 |
Ki > 1000 nM
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CP0405407
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1-[2-Furan-2-yl-8-methyl-9-(4-methyl-piperazin-1-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-(4-methoxy-phenyl)-urea
Show/Hide
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C24H26N10O3
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1
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| 1 |
Ki > 1000 nM
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CP0409362
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2-[4-(5-Amino-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-phenoxy]-N-(4-iodo-phenyl)-acetamide
Show/Hide
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C28H23IN8O2
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1
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| 1 |
Ki > 1000 nM
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CP0430285
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7-Phenethyl-2-phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C20H17N7
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1
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| 1 |
Ki > 1000 nM
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CP0436749
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ethyl 2-[4-[7-amino-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl]phenoxy]acetate
Show/Hide
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C24H23N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0453036
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2-[4-[7-amino-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl]phenoxy]acetic acid
Show/Hide
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C22H19N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0487506
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2-(2-Ethoxy-phenyl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
Show/Hide
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C22H21N7O
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1
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| 1 |
Ki > 1000 nM
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CP0374591
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[(4-morpholin-4-ylsulfonylphenyl)carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C23H28N8O8S
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1
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| 1 |
Ki > 1000 nM
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CP0377943
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[[4-[methyl(prop-2-enyl)sulfamoyl]phenyl]carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C23H28N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0378050
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(2S,3S,4R)-5-[6-[[4-(tert-butylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C23H30N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0391549
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(2S,3S,4R)-5-[6-[[4-(2,5-dihydropyrrol-1-ylsulfonyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C23H26N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0391650
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(2S,3S,4R)-5-[6-[[4-(diethylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C23H30N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393965
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(2S,3S,4R)-5-[6-[[4-(dipropylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H34N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393982
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[(4-pyrrolidin-1-ylsulfonylphenyl)carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C23H28N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393984
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(2S,3S,4R)-5-[6-[[4-[bis(2-chloroethyl)sulfamoyl]phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C23H28Cl2N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393986
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(2S,3S,4R)-5-[6-[[4-(1-adamantylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C29H36N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393987
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(2S,3S,4R)-5-[6-[[4-(cyclopentylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C24H30N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393988
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[[4-[methyl(propan-2-yl)sulfamoyl]phenyl]carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C23H30N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393989
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(2S,3S,4R)-5-[6-[[4-(dimethylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C21H26N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0393991
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(2S,3S,4R)-5-[6-[[4-[bis(prop-2-enyl)sulfamoyl]phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H30N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0435321
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[[4-(propylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C22H28N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0448715
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(2S,3S,4R)-5-[6-[[4-(benzylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C26H28N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0451745
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[[4-(pentylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C24H32N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0480654
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[(4-piperidin-1-ylsulfonylphenyl)carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C24H30N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0480655
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(2S,3S,4R)-N-ethyl-5-[6-[[4-(ethylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C21H26N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0480656
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(2S,3S,4R)-5-[6-[[4-(cyclohexylsulfamoyl)phenyl]carbamoylamino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Show/Hide
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C25H32N8O7S
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1
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| 1 |
Ki > 1000 nM
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CP0493050
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(2S,3S,4R)-N-ethyl-3,4-dihydroxy-5-[6-[[4-[(4-methoxyphenyl)sulfamoyl]phenyl]carbamoylamino]purin-9-yl]oxolane-2-carboxamide
Show/Hide
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C26H28N8O8S
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1
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| 1 |
Ki > 1000 nM
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CP0376366
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1-[8-(2-benzyloxy-ethyl)-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-3-yl-urea
Show/Hide
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C25H21N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0376368
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1-[8-(2-benzyloxy-ethyl)-2-furan-2-yl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-4-yl-urea
Show/Hide
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C25H21N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0394720
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1-[2-furan-2-yl-8-(2-hydroxy-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-3-yl-urea
Show/Hide
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C18H15N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0408271
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1-[2-furan-2-yl-8-(2-hydroxy-ethyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-4-yl-urea
Show/Hide
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C18H15N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0449386
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5-[[(4-pyridyl)amino]carbonyl]amino-[8-(3-benzyloxypropyl)-2-(furan-2-yl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine
Show/Hide
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C26H23N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0453022
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1-[2-furan-2-yl-8-(3-hydroxy-propyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-3-pyridin-4-yl-urea
Show/Hide
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C19H17N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0374603
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1-Benzyl-7-methyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
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C18H19N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0375694
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1-Benzyl-7-cyclopropyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
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C20H21N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0375735
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1-Benzyl-7-phenyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C23H21N5O2
|
1
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| 1 |
Ki > 1000 nM
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CP0375736
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1-Benzyl-7-(4-methoxy-phenyl)-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
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C24H23N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0377977
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1-Benzyl-7-phenyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
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C24H22N4O2
|
1
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| 1 |
Ki > 1000 nM
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CP0377978
|
1-Benzyl-7-ethyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0393417
|
1-Benzyl-7-ethyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0394888
|
1-Benzyl-7-tert-butyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C21H25N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402019
|
1-Benzyl-7-methyl-3-allyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C18H17N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402020
|
1-Benzyl-6,7-dimethyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H22N4O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402021
|
1-Benzyl-7-ethyl-6-methyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402022
|
1-Benzyl-7-(4-fluoro-phenyl)-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C23H20FN5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402023
|
1,3-Dipropyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402024
|
1,3,7-Trimethyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C10H11N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402026
|
1-Benzyl-6,7-dimethyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402027
|
1-Benzyl-7-biphenyl-4-yl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C29H25N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402028
|
1,3-Dimethyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C15H13N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0402029
|
1-Benzyl-7-methyl-3-prop-2-ynyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C18H15N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0423157
|
1-Benzyl-7-cyclohexyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0423158
|
1-Benzyl-7-methyl-1H,3H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C15H13N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0423159
|
1-Benzyl-7-methyl-3-(2-hydroxy-ethyl)-1H,8Himidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C17H17N5O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0431376
|
1,3-Diisobutyl-7-phenyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C21H25N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0431377
|
1-Benzyl-3-(2-dimethylamino-ethyl)-7-methyl-1H,8Himidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H22N6O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0431379
|
(1-Benzyl-7-methyl-2,4-dioxo-1,2,4,8-tetrahydro-imidazo-[2,1-f]purin-3-yl)-acetic acid ethyl ester
Show/Hide
|
C19H19N5O4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0435571
|
1-Benzyl-7-methyl-3-propyl-1H,6H-pyrrolo[2,1-f]purine-2,4-dione
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0439600
|
1-Benzyl-7-methyl-3-(2-hydroxy-propyl)-1H,8H-imidazo-[2,1-f]purine-2,4-dione
Show/Hide
|
C18H19N5O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0452625
|
1-Benzyl-8-ethyl-7-methyl-3-propyl-1H,8H-imidazo[2,1-f]-purine-2,4-dione
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0452626
|
1-Benzyl-7-methyl-3-(2-oxo-propyl)-1H,8H-imidazo-[2,1-f]purine-2,4-dione
Show/Hide
|
C18H17N5O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0474676
|
1-Benzyl-8-(2-hydroxy-1-methyl-ethyl)-7-methyl-1H,8Himidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C18H19N5O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0474680
|
1-Benzyl-8-ethyl-7-methyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C17H17N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0474681
|
1-Benzyl-7-isopropyl-3-propyl-1H,8H-imidazo[2,1-f]purine-2,4-dione
Show/Hide
|
C20H23N5O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0870348
|
7-methyl-3-propyl-1-(pyridin-4-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride
Show/Hide
|
C17H19ClN6O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0870350
|
7-methyl-3-propyl-1-(pyridin-3-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride
Show/Hide
|
C17H19ClN6O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0870380
|
7-methyl-3-propyl-1-(pyridin-2-ylmethyl)-1H-imidazo[1,2-a]purine-2,4(3H,8H)-dione hydrochloride
Show/Hide
|
C17H19ClN6O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374607
|
2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C17H13N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374608
|
2-(4-Fluoro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C16H10FN3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374610
|
2-Phenyl-2H-pyrazolo[4,3-c]quinoline
Show/Hide
|
C16H11N3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374611
|
4-Methoxy-2-phenyl-2H-pyrazolo[4,3-c]quinoline
Show/Hide
|
C17H13N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0374612
|
2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinoline-4-thione
Show/Hide
|
C16H11N3S
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0375688
|
2-Phenyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C16H11N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0375689
|
2-p-Tolyl-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C17H13N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0375691
|
2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C18H15N3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0375706
|
Benzyl-(2-phenyl-2H-pyrazolo[4,3-c]quinolin-4-yl)-amine
Show/Hide
|
C23H18N4
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0394767
|
2-(2-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C16H10ClN3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0448674
|
2-(4-Chloro-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one
Show/Hide
|
C16H10ClN3O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373607
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-oxo-2-(pyridin-4-ylamino)ethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C25H26N8O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373608
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-iodophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26IN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373609
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-chlorophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26ClN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373610
|
(2S,3S,4R,5R)-5-(6-(4-(2-(cyclohexylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H33N7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0394486
|
(2S,3S,4R,5R)-5-(6-(4-(2-(benzylamino)-2-oxoethoxy)phenylamino)-2-chloro-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H28ClN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0399501
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-morpholinophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C30H34N8O7
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0399503
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-methoxybenzylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C28H31N7O7
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0405561
|
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-(cyclohexylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H32ClN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0405562
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-bromophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26BrN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0407994
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-(4-methoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H29N7O7
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0408013
|
(2S,3S,4R,5R)-5-(6-(4-(2-(3,4-dimethoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C28H31N7O8
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0412406
|
(2S,3S,4R,5R)-5-(6-(4-(2-(benzylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H29N7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0412531
|
(2S,3S,4R,5R)-5-(6-(4-(2-(benzo[d][1,3]dioxol-5-ylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H27N7O8
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0421958
|
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-oxo-2-(phenylamino)ethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26ClN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0432015
|
(2S,3S,4R,5R)-N-ethyl-3,4-dihydroxy-5-(6-(4-(2-oxo-2-(phenylamino)ethoxy)phenylamino)-9H-purin-9-yl)-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H27N7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0454289
|
(2S,3S,4R,5R)-5-(6-(4-(2-(3,5-dimethoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C28H31N7O8
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0454290
|
(2S,3S,4R,5R)-5-(2-chloro-6-(4-(2-(4-methoxyphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C27H28ClN7O7
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0457726
|
(2S,3S,4R,5R)-5-(6-(4-(2-(4-tert-butylphenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C30H35N7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0457727
|
(2S,3S,4R,5R)-N-ethyl-5-(6-(4-(2-(4-fluorophenylamino)-2-oxoethoxy)phenylamino)-9H-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
Show/Hide
|
C26H26FN7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0493012
|
1-deoxy-1-[6-{4-[(2-trifluoromethyl-phenylcarbamoyl)-methoxy]-phenylamino}-9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
|
C27H26F3N7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0099921
|
N-(1,3-benzodioxol-5-yl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
|
C24H27N7O6
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0371890
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-[4-(2-methylpropyl)phenyl]acetamide
Show/Hide
|
C27H35N7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0371891
|
N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H26ClN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373431
|
2-[4-bromo-3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-chlorophenyl)acetamide
Show/Hide
|
C23H25BrClN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373432
|
2-[4-chloro-3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-chlorophenyl)acetamide
Show/Hide
|
C23H25Cl2N7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373433
|
N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)pyrazol-1-yl]acetamide
Show/Hide
|
C22H24ClN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373434
|
N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-ethylpyrazol-1-yl]acetamide
Show/Hide
|
C24H28ClN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373435
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-fluorophenyl)acetamide
Show/Hide
|
C23H26FN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373436
|
N-[4-(dimethylamino)phenyl]-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C25H32N8O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373438
|
2-(3,4-Dimethoxy-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C25H31N7O5
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373439
|
N-(3-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H26ClN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0373440
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-iodophenyl)acetamide
Show/Hide
|
C23H26IN7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0378549
|
2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-methylphenyl)acetamide
Show/Hide
|
C24H29N7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0382371
|
N-(3,4-dichlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
|
C23H25Cl2N7O3
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0399756
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2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-methoxyphenyl)acetamide
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C24H29N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0399758
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2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(3-methoxyphenyl)acetamide
Show/Hide
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C24H29N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0399759
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N-(3,4-dimethylphenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
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C25H31N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0435132
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N-(3,4-dimethoxyphenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
Show/Hide
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C25H31N7O5
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1
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| 1 |
Ki > 1000 nM
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CP0435133
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N-(4-bromophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]acetamide
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C23H26BrN7O3
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1
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| 1 |
Ki > 1000 nM
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CP0440938
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2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-phenylacetamide
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C23H27N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0440939
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2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-naphthalen-1-ylacetamide
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C27H29N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0459941
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N-(4-chlorophenyl)-2-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-4-iodo-5-methylpyrazol-1-yl]acetamide
Show/Hide
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C23H25ClIN7O3
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1
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| 1 |
Ki > 1000 nM
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CP0246556
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8-(4-Amino-phenyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C17H21N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0373225
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1-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-3-(3-methoxy-phenyl)-urea
Show/Hide
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C25H28N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0374684
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4-{2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-acetylamino}-benzoic acid ethyl ester
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C26H31N7O6
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1
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| 1 |
Ki > 1000 nM
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CP0374742
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8-{2-Methyl-5-[2-oxo-2-(4-phenyl-piperazin-1-yl)-ethoxy]-2H-pyrazol-3-yl}-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C27H34N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0374815
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N-(3,4-dimethoxyphenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
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C25H31N7O6
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1
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| 1 |
Ki > 1000 nM
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CP0375424
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-[4-[(4-nitrophenyl)methoxy]phenyl]acetamide
Show/Hide
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C30H32N8O6
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1
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| 1 |
Ki > 1000 nM
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CP0375425
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-p-tolyl-acetamide
Show/Hide
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C24H29N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0375426
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8-{2-Methyl-5-[2-(4-methyl-piperazin-1-yl)-2-oxo-ethoxy]-2H-pyrazol-3-yl}-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C22H32N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0375493
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-fluorophenyl)acetamide
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C23H26FN7O3
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1
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| 1 |
Ki > 1000 nM
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CP0375834
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-[4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]acetamide
Show/Hide
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C31H32F3N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0376492
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4-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]amino]-4-oxobutanoic acid
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C19H25N7O5
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1
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| 1 |
Ki > 1000 nM
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CP0376493
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N-(4-acetylphenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
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C25H29N7O5
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1
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| 1 |
Ki > 1000 nM
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CP0376494
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N-(3,4-dichlorophenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
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C23H25Cl2N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0376495
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2-[5-[1,3-bis(2-methylpropyl)-2,6-dioxo-7H-purin-8-yl]-2-methylpyrazol-3-yl]oxy-N-(4-bromophenyl)acetamide
Show/Hide
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C25H30BrN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0380156
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide
Show/Hide
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C23H26FN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0380221
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(S)-N-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-2-phenyl-propionamide
Show/Hide
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C24H29N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0380266
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2-(3,4-Difluoro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
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C23H25F2N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0380267
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2-(3,4-Dimethoxy-phenyl)-N-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-acetamide
Show/Hide
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C27H31N5O5
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1
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| 1 |
Ki > 1000 nM
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CP0392623
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-(4-morpholin-4-yl-phenyl)-acetamide
Show/Hide
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C27H34N8O5
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1
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| 1 |
Ki > 1000 nM
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CP0392677
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(R)-N-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-2-phenyl-propionamide
Show/Hide
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C24H29N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0392679
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2-[5-[1,3-bis(2-methylpropyl)-2,6-dioxo-7H-purin-8-yl]-1-methylpyrazol-3-yl]oxy-N-(4-bromophenyl)acetamide
Show/Hide
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C25H30BrN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0392722
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N-[5-(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-phenylacetamide
Show/Hide
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C19H19N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0395373
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-[4-(trifluoromethyl)phenyl]acetamide
Show/Hide
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C24H26F3N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0395424
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2-(4-Dimethylamino-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
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C25H32N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0397484
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-methoxyphenyl)acetamide
Show/Hide
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C24H29N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0402118
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8-(5-Amino-2-methyl-2H-pyrazol-3-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C15H21N7O2
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1
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| 1 |
Ki > 1000 nM
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CP0402119
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(3-fluorophenyl)acetamide
Show/Hide
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C23H26FN7O3
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1
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| 1 |
Ki > 1000 nM
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CP0404316
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1-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-3-(4-methoxy-phenyl)-urea
Show/Hide
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C23H28N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0409273
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]acetamide
Show/Hide
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C31H32F3N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0414779
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2-[6-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-pyridazin-3-yloxy]-N-(4-iodo-phenyl)-acetamide
Show/Hide
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C23H24IN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0420840
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-isoxazol-3-yloxy]-N-(4-methoxy-phenyl)-acetamide
Show/Hide
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C23H26N6O6
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1
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| 1 |
Ki > 1000 nM
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CP0423138
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2-(4-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
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C23H26ClN7O3
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1
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| 1 |
Ki > 1000 nM
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CP0426011
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5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-2-methyl-2H-pyrazole-3-carboxylic acid
Show/Hide
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C16H20N6O4
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1
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| 1 |
Ki > 1000 nM
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CP0426029
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(3,4,5-trimethoxyphenyl)acetamide
Show/Hide
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C26H33N7O6
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1
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| 1 |
Ki > 1000 nM
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CP0429027
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-phenylacetamide
Show/Hide
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C23H27N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0429028
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-2-methylpyrazol-3-yl]-2-phenylacetamide
Show/Hide
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C23H27N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0429029
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1-(4-Dimethylamino-phenyl)-3-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-urea
Show/Hide
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C24H31N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0430224
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N-(4-bromophenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
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C23H26BrN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0430234
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8-(5-Amino-1-methyl-1H-pyrazol-3-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C15H21N7O2
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1
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| 1 |
Ki > 1000 nM
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CP0430510
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4-{2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-acetylamino}-benzoic acid
Show/Hide
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C24H27N7O6
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1
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| 1 |
Ki > 1000 nM
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CP0430511
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2-[5-(1,3-Diisobutyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-2-methyl-2H-pyrazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide
Show/Hide
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C25H30FN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0430514
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8-(5-Amino-1-methyl-1H-pyrazol-3-yl)-1,3-dimethyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C11H13N7O2
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1
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| 1 |
Ki > 1000 nM
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CP0430515
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N-(4-butan-2-ylphenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
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C27H35N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0430550
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N-(1,3-benzodioxol-5-yl)-2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1,2-oxazol-3-yl]oxy]acetamide
Show/Hide
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C23H24N6O7
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1
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| 1 |
Ki > 1000 nM
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CP0430566
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1-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-3-(3-methoxy-phenyl)-urea
Show/Hide
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C23H28N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0430569
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(3-methoxyphenyl)acetamide
Show/Hide
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C24H29N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0430570
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8-(5-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-2-oxo-ethoxy}-2-methyl-2H-pyrazol-3-yl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C27H33FN8O4
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1
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| 1 |
Ki > 1000 nM
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CP0430592
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-(3-methyl-1,4-dihydro-pyridin-4-yl)-acetamide
Show/Hide
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C23H28N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0436670
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8-{5-[2-(4-Benzyl-piperazin-1-yl)-2-oxo-ethoxy]-2-methyl-2H-pyrazol-3-yl}-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C28H36N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0448476
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2-[5-(1,3-Diisobutyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide
Show/Hide
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C25H30FN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0448526
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-nitrophenyl)acetamide
Show/Hide
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C23H26N8O5
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1
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| 1 |
Ki > 1000 nM
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CP0451903
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-isoxazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide
Show/Hide
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C22H23FN6O5
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1
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| 1 |
Ki > 1000 nM
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CP0451918
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1-(3-Chloro-phenyl)-3-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-urea
Show/Hide
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C22H25ClN8O3
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1
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| 1 |
Ki > 1000 nM
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CP0451994
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1-(3-Chloro-phenyl)-3-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl]-urea
Show/Hide
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C24H25ClN6O3
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1
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| 1 |
Ki > 1000 nM
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CP0454714
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N-(3,4-dimethoxyphenyl)-2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1,2-oxazol-3-yl]oxy]acetamide
Show/Hide
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C24H28N6O7
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1
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| 1 |
Ki > 1000 nM
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CP0455691
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-phenylmethoxyphenyl)acetamide
Show/Hide
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C30H33N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0455694
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-hydroxyphenyl)acetamide
Show/Hide
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C23H27N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0459866
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-pyridin-2-yloxy]-N-(4-iodo-phenyl)-acetamide
Show/Hide
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C24H25IN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0460823
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-(4-hydroxy-3-methoxyphenyl)acetamide
Show/Hide
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C24H29N7O5
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1
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| 1 |
Ki > 1000 nM
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CP0463661
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-pyridin-4-yl-acetamide
Show/Hide
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C22H26N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0463678
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N-(3,4-dimethylphenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
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C25H31N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0480744
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2-(3-Chloro-phenyl)-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
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C23H26ClN7O3
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1
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| 1 |
Ki > 1000 nM
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CP0486451
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N-[4-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)phenyl]-2-phenylacetamide
Show/Hide
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C25H27N5O3
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1
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| 1 |
Ki > 1000 nM
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CP0487097
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2-Benzo[1,3]dioxol-5-yl-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-acetamide
Show/Hide
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C24H27N7O5
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1
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| 1 |
Ki > 1000 nM
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CP0489978
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N-[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]-2-[4-(2-methylpropyl)phenyl]acetamide
Show/Hide
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C27H35N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0521937
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8-(4-Amino-phenyl)-7-methyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione
Show/Hide
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C18H23N5O2
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1
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| 1 |
Ki > 1000 nM
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CP0860964
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N-(4-Bromo-phenyl)-2-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-acetamide
Show/Hide
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C23H26BrN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0878146
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2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yloxy]-N-(4-fluoro-phenyl)-acetamide
Show/Hide
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C23H26FN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0885838
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4-Amino-N-[5-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol-3-yl]-butyramide hydrochloride
Show/Hide
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C19H29ClN8O3
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1
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| 1 |
Ki > 1000 nM
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CP0895197
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8-{2-Methyl-5-[2-oxo-2-(4-phenyl-piperazin-1-yl)-ethoxy]-2H-pyrazol-3-yl}-1,3-bis-((E)-propenyl)-3,7-dihydro-purine-2,6-dione
Show/Hide
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C27H30N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0385420
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1-[11-(furan-2-yl)-3-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C27H24N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0385421
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1-[11-(furan-2-yl)-4-(3-phenylpropyl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,5,7,10-pentaen-8-yl]-3-(4-methoxyphenyl)urea
Show/Hide
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C27H24N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0387993
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11-(furan-2-yl)-3-methyl-8-(4-phenylpiperazin-1-yl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaene
Show/Hide
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C21H20N8O
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1
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| 1 |
Ki > 1000 nM
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CP0401404
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4-[11-(furan-2-yl)-3-methyl-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaen-8-yl]morpholine
Show/Hide
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C15H15N7O2
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1
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| 1 |
Ki > 1000 nM
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CP0401405
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11-(furan-2-yl)-3-methyl-8-(4-methylpiperazin-1-yl)-3,4,7,9,10,12-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2(6),4,7,10-pentaene
Show/Hide
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C16H18N8O
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1
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| 1 |
Ki > 1000 nM
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CP0428653
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,11-pentazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-pyridin-4-ylurea
Show/Hide
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C18H14N8O2
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1
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| 1 |
Ki > 1000 nM
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CP0387788
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8-[2-methyl-5-[(4-oxo-3H-quinazolin-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H26N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0387790
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8-[3-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C22H21ClFN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0387791
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8-[5-[[4,6-bis(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C25H24F6N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0387798
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8-[3-[(6-methoxy-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H25N7O5
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1
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| 1 |
Ki > 1000 nM
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CP0387799
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6-[5-(1H-benzimidazol-2-ylmethoxy)-2-methylpyrazol-3-yl]-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
Show/Hide
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C24H27N7O3
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1
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| 1 |
Ki > 1000 nM
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CP0387800
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2-[5-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-1-methylpyrazol-3-yl]oxy-N-(4-fluorophenyl)acetamide
Show/Hide
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C24H27FN6O4
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1
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| 1 |
Ki > 1000 nM
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CP0391927
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8-[5-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H24ClFN8O3
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1
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| 1 |
Ki > 1000 nM
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CP0391929
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8-[5-[(6-methoxy-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H28N8O4
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1
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| 1 |
Ki > 1000 nM
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CP0391930
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ethyl 2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxymethyl]-3H-benzimidazole-5-carboxylate
Show/Hide
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C26H30N8O5
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1
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| 1 |
Ki > 1000 nM
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CP0391931
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8-[3-[(6-bromo-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C22H22BrN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0403597
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8-(2-methyl-5-oxo-1H-pyrazol-3-yl)-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C15H20N6O3
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1
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| 1 |
Ki > 1000 nM
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CP0403599
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8-[5-(1H-benzo[f]benzimidazol-2-ylmethoxy)-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C27H28N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0403600
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8-[3-[(6-chloro-1H-benzimidazol-2-yl)methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C22H22ClN7O4
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1
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| 1 |
Ki > 1000 nM
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CP0403601
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8-[3-[[4-chloro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H21ClF3N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0403602
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8-[2-methyl-5-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H25F3N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0403603
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2-[[5-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-1-methylpyrazol-3-yl]oxymethyl]-3H-benzimidazole-5-carboxylic acid
Show/Hide
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C24H26N8O5
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1
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| 1 |
Ki > 1000 nM
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CP0403606
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8-[5-[(6-bromo-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H25BrN8O3
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1
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| 1 |
Ki > 1000 nM
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CP0403615
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8-[5-(1H-benzimidazol-2-ylmethoxy)-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H26N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0418732
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8-[2-methyl-5-[(6-methyl-1H-benzimidazol-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H28N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0418733
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8-[5-[[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C25H28N8O5
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1
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| 1 |
Ki > 1000 nM
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CP0437627
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8-[2-methyl-5-[(4-methyl-1H-benzimidazol-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H28N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0437628
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1,3-dipropyl-8-[3-[[6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-1,2-oxazol-5-yl]-7H-purine-2,6-dione
Show/Hide
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C23H22F3N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0437629
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8-[3-(1H-benzimidazol-2-ylmethoxy)-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C22H23N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0437630
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8-[5-[(6-fluoro-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H25FN8O3
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1
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| 1 |
Ki > 1000 nM
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CP0437642
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8-[5-[(5,6-dimethyl-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C25H30N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0437643
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N-(1,3-benzodioxol-5-yl)-2-[5-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)-1-methylpyrazol-3-yl]oxyacetamide
Show/Hide
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C25H28N6O6
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1
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| 1 |
Ki > 1000 nM
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CP0462138
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8-[3-[[4,6-bis(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-1,2-oxazol-5-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H21F6N7O4
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1
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| 1 |
Ki > 1000 nM
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CP0462139
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8-[5-[(6-chloro-1H-benzimidazol-2-yl)methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H25ClN8O3
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1
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| 1 |
Ki > 1000 nM
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CP0462151
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8-[2-methyl-5-[(6-nitro-1H-benzimidazol-2-yl)methoxy]pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C23H25N9O5
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1
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| 1 |
Ki > 1000 nM
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CP0480462
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8-[2-methyl-5-(7H-purin-8-ylmethoxy)pyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C21H24N10O3
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1
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| 1 |
Ki > 1000 nM
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CP0496331
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8-[5-[[4-chloro-6-(trifluoromethyl)-1H-benzimidazol-2-yl]methoxy]-2-methylpyrazol-3-yl]-1,3-dipropyl-7H-purine-2,6-dione
Show/Hide
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C24H24ClF3N8O3
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1
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| 1 |
Ki > 1000 nM
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CP0375533
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4-[4-[(2-chlorophenyl)methyl]piperazine-1-carbonyl]-N-(4-oxo-3,1-benzothiazin-2-yl)benzamide
Show/Hide
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C27H23ClN4O3S
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1
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| 1 |
Ki > 1000 nM
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CP0375536
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3-(3-methoxyphenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)prop-2-ynamide
Show/Hide
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C18H12N2O3S
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1
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| 1 |
Ki >= 1000 nM
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CP0420745
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(E)-3-(3-chlorophenyl)-N-(4-oxo-3,1-benzothiazin-2-yl)prop-2-enamide
Show/Hide
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C17H11ClN2O2S
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1
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| 1 |
Ki > 1000 nM
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CP0380794
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1,3-bis(4-fluorophenyl)-2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C24H17F2N9O
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1
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| 1 |
Ki > 1000 nM
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CP0380796
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1,3-bis(4-bromophenyl)-2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C24H17Br2N9O
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1
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| 1 |
Ki > 1000 nM
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CP0389282
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2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-1,3-bis(3-methoxyphenyl)guanidine
Show/Hide
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C26H23N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0389283
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1,3-bis(4-chlorophenyl)-2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C24H17Cl2N9O
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1
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| 1 |
Ki > 1000 nM
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CP0389286
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1,3-bis(4-cyanophenyl)-2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C10H12N4O5S
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1
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| 1 |
Ki > 1000 nM
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CP0389287
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1,3-bis(3-chlorophenyl)-2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C24H17Cl2N9O
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1
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| 1 |
Ki > 1000 nM
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CP0395988
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2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-1,3-bis(4-methoxyphenyl)guanidine
Show/Hide
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C26H23N9O3
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1
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| 1 |
Ki > 1000 nM
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CP0396000
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2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-1,3-bis[3-(trifluoromethyl)phenyl]guanidine
Show/Hide
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C26H17F6N9O
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1
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| 1 |
Ki > 1000 nM
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CP0396001
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2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-1,3-diphenylguanidine
Show/Hide
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C24H19N9O
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1
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| 1 |
Ki > 1000 nM
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CP0401226
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-2,3-di(propan-2-yl)guanidine
Show/Hide
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C18H23N9O
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1
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| 1 |
Ki > 1000 nM
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CP0401227
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2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-1,3-bis(4-methylphenyl)guanidine
Show/Hide
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C26H23N9O
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1
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| 1 |
Ki > 1000 nM
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CP0401228
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2-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-1,3-bis(4-nitrophenyl)guanidine
Show/Hide
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C24H17N11O5
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1
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| 1 |
Ki > 1000 nM
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CP0401229
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1,2-dicyclohexyl-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C24H31N9O
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1
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| 1 |
Ki > 1000 nM
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CP0401230
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2-[3-(dimethylamino)propyl]-1-ethyl-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]guanidine
Show/Hide
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C19H26N10O
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1
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| 1 |
Ki > 1000 nM
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|
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CP0855288
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(R/S)-N-[6-(1-Phenylethoxy)-2-(propylsulfanyl)pyrimidin-4-yl]acetamide
Show/Hide
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C17H21N3O2S
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1
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| 1 |
Ki > 1000 nM
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|
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CP0855289
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(R/S)-N-[2-(Benzylsulfanyl)-6-(butan-2-yloxy)pyrimidin-4-yl]acetamide
Show/Hide
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C17H21N3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0864899
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(R/S)-N-{2-[(1-Phenylethyl)sulfanyl]-6-propoxypyrimidin-4-yl}acetamide
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C17H21N3O2S
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1
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| 1 |
Ki > 1000 nM
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CP0420799
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8-[4-[4-(3-chloro-4-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C25H27ClN6O5S
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1
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| 1 |
Ki > 1000 nM
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CP0420800
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8-[4-[4-(4-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-3-methyl-1-propyl-7H-purine-2,6-dione
Show/Hide
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C25H27ClN6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0420803
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8-[4-[4-(4-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C24H25BrN6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0420820
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8-[4-[4-(3-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C24H25FN6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0420866
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8-[4-[4-(3-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25BrN6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0420867
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8-[4-[4-(3-fluoro-4-methoxyphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C25H27FN6O5S
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1
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| 1 |
Ki > 1000 nM
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CP0420868
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8-[4-[4-(4-chloro-2-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H24ClFN6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0423080
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8-[4-[4-(2-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C24H25FN6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0424431
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8-[4-[4-(4-methylphenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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C25H28N6O4S
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1
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| 1 |
Ki > 1000 nM
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CP0869451
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8-(4-((4-(1-Phenylethyl)piperazin-1-yl)sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
Show/Hide
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C26H30N6O4S
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1
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| 1 |
Ki >= 1000 nM
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CP0099745
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4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imidazole
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C16H18N2O2
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1
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| 1 |
Ki > 1000 nM
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CP0239657
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cyclopropyl-[4-(3-piperidin-1-ylpropoxy)phenyl]methanone
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C18H25NO2
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1
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| 1 |
Ki > 1000 nM
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CP0542598
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4-phenyl-7-(3-pyrrolidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
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C24H26N4O
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1
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| 1 |
Ki > 1000 nM
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CP0551161
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4-phenyl-7-(3-piperidin-1-ylpropoxy)-5H-indeno[1,2-d]pyrimidin-2-amine
Show/Hide
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C25H28N4O
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1
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| 1 |
Ki > 1000 nM
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CP0383333
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1-deoxy-1-{6-[N'-(pyridine-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
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C18H20N8O5
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1
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| 1 |
Ki > 5000 nM
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CP0408626
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1-deoxy-1-{6-[N'-(1-methyl-4-nitro-1H-imidazole-2-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C17H20N10O7
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1
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| 1 |
Ki > 5000 nM
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CP0408811
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1-deoxy-1-[6-(N'-benzoyl-hydrazino)-2-chloro-9H-purin-9-yl]-N-ethyl-beta-Dribofuranuronamide
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C19H20ClN7O5
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1
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| 1 |
Ki > 5000 nM
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CP0441868
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1-deoxy-1-{2-chloro-6-[N'-(5-methyl-isoxazole-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C17H19ClN8O6
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1
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| 1 |
Ki > 5000 nM
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CP0442338
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1-deoxy-1-{2-chloro-6-[N'-(5-phenyl-isoxazole-3-carbonyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C22H21ClN8O6
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1
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| 1 |
Ki > 5000 nM
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CP0445616
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1-deoxy-1-[6-(N'-(4-chlorobenzoyl)hydrazino)-9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C19H20ClN7O5
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1
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| 1 |
Ki > 5000 nM
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CP0499897
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1-deoxy-1-[6-(N'-benzoylhydrazino)-9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide
Show/Hide
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C19H21N7O5
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1
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| 1 |
Ki > 5000 nM
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CP0387747
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4-benzyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0387748
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(8S)-4-benzyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0387749
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8-ethyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-4-prop-2-enyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C23H25N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0387750
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4-benzyl-8-ethyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0459537
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(8R)-4-benzyl-2-(5-methoxy-2-methylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0459538
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4-benzyl-8-ethyl-2-(3-methoxy-1,2-oxazol-5-yl)-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H20N6O3
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1
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| 1 |
Ki > 5000 nM
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CP0459539
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4-benzyl-2-(3-methoxy-1,2-oxazol-5-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C19H18N6O3
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1
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| 1 |
Ki > 5000 nM
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CP0459540
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4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-methyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C20H21N7O
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1
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| 1 |
Ki > 5000 nM
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CP0472589
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(8R)-4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-ethyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki > 5000 nM
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CP0484705
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8-methyl-2-(2-methyl-5-phenylmethoxypyrazol-3-yl)-4-prop-2-enyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C22H23N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0484708
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4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-ethyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki > 5000 nM
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CP0484714
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(8S)-4-benzyl-2-(2,5-dimethylpyrazol-3-yl)-8-ethyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki > 5000 nM
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CP0851863
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(R)-4-Allyl-7,8-dihydro-8-methyl-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 5000 nM
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CP0851864
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(R)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0851865
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(S)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 5000 nM
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CP0851866
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(R,S)-4-Allyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-8-methyl-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0851867
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(R,S)-4-Benzyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C21H23N7O
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1
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| 1 |
Ki > 5000 nM
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CP0851868
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(R,S)-4-Benzyl-7,8-dihydro-8-methyl-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C20H21N7O
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1
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| 1 |
Ki > 5000 nM
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CP0851869
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0888367
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(R)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 5000 nM
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CP0888369
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O
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1
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| 1 |
Ki > 5000 nM
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CP0894369
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(R,S)-4-Allyl-7,8-dihydro-2-(3-methoxyisoxazol-5-yl)-8-methyl-1Himidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C15H16N6O3
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1
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| 1 |
Ki > 5000 nM
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CP0894370
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(R,S)-4-Allyl-7,8-dihydro-8-methyl-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 5000 nM
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CP0894373
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(S)-4-Allyl-7,8-dihydro-8-methyl-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 5000 nM
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CP0894374
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(S)-4-Allyl-8-ethyl-7,8-dihydro-2-(3-methoxy-1-methyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O2
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1
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| 1 |
Ki > 5000 nM
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CP0903359
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(R,S)-4-Allyl-7,8-dihydro-8-methyl-2-(1,5-dimethyl-1H-pyrazol-3-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C16H19N7O
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1
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| 1 |
Ki > 5000 nM
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CP0921109
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(R,S)-4-Allyl-8-ethyl-7,8-dihydro-2-(1,3-dimethyl-1H-pyrazol-5-yl)-1H-imidazo[2,1-i]purin-5(4H)-one
Show/Hide
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C17H21N7O
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1
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| 1 |
Ki > 5000 nM
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CP0398649
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-[(4-nitrophenyl)methyl]piperidin-4-yl]urea
Show/Hide
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C24H24N10O4
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1
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| 1 |
Ki > 5000 nM
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CP0399747
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-(pyridin-3-ylmethyl)piperidin-4-yl]urea
Show/Hide
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C23H24N10O2
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1
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| 1 |
Ki > 5000 nM
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CP0399755
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-[(4-methylphenyl)methyl]piperidin-4-yl]urea
Show/Hide
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C25H27N9O2
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1
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| 1 |
Ki > 5000 nM
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CP0410153
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N-cyclopentyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C23H28N10O3
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1
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| 1 |
Ki > 5000 nM
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CP0410320
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N-benzyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C25H26N10O3
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1
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| 1 |
Ki > 5000 nM
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CP0410322
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N-cycloheptyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C25H32N10O3
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1
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| 1 |
Ki > 5000 nM
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CP0415669
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-(pyridin-4-ylmethyl)piperidin-4-yl]urea
Show/Hide
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C23H24N10O2
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1
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| 1 |
Ki > 5000 nM
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CP0415670
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N-cyclohexyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C24H30N10O3
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1
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| 1 |
Ki > 5000 nM
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CP0415671
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-propan-2-ylpiperidine-1-carboxamide
Show/Hide
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C21H26N10O3
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1
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| 1 |
Ki > 5000 nM
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CP0423985
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-(1-methylpiperidin-4-yl)urea
Show/Hide
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C18H21N9O2
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1
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| 1 |
Ki > 5000 nM
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CP0424051
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-[1-[(4-methoxyphenyl)methyl]piperidin-4-yl]urea
Show/Hide
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C25H27N9O3
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1
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| 1 |
Ki > 5000 nM
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CP0436047
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1-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C24H24FN9O2
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1
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| 1 |
Ki > 5000 nM
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CP0445368
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N-ethyl-4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]piperidine-1-carboxamide
Show/Hide
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C20H24N10O3
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1
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| 1 |
Ki > 5000 nM
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CP0445370
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4-[[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]carbamoylamino]-N-[(4-methoxyphenyl)methyl]piperidine-1-carboxamide
Show/Hide
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C26H28N10O4
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1
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| 1 |
Ki > 5000 nM
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CP0445371
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1-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]-3-piperidin-4-ylurea
Show/Hide
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C17H19N9O2
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1
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| 1 |
Ki > 5000 nM
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CP0483179
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1-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-3-[4-(furan-2-yl)-11-methyl-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(12),2,4,7,9-pentaen-7-yl]urea
Show/Hide
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C24H24ClN9O2
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1
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| 1 |
Ki > 5000 nM
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CP0867155
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N-[1-(Cyclohexylmethyl)piperidin-4-yl]-N'-[2-(2-furyl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-urea hydrochloride
Show/Hide
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C24H32ClN9O2
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1
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| 1 |
Ki > 5000 nM
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