General Information of the Compound
Compound ID
CP0494064
Compound Name
N-[2,7-bis(furan-2-yl)-1,3-benzoxazol-5-yl]-3-[4-[4-(2-ethoxyethoxy)phenyl]piperazin-1-yl]propanamide
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Structure
Formula
C32H34N4O6
Molecular Weight
570.646
Canonical SMILES
CCOCCOc1ccc(cc1)N1CCN(CCC(=O)Nc2cc(-c3ccco3)c3oc(nc3c2)-c2ccco2)CC1
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InChI
InChI=1S/C32H34N4O6/c1-2-38-19-20-39-25-9-7-24(8-10-25)36-15-13-35(14-16-36)12-11-30(37)33-23-21-26(28-5-3-17-40-28)31-27(22-23)34-32(42-31)29-6-4-18-41-29/h3-10,17-18,21-22H,2,11-16,19-20H2,1H3,(H,33,37)
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InChIKey
AVSXERUVYKEECX-UHFFFAOYSA-N
Physicochemical Property
logP
5.9139
Rotatable Bonds
12
Heavy Atom Count
42
Polar Areas
106.35
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145989729
ChEMBL ID
CHEMBL4289393
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS