Brief Information of the Compound and Protein
Compound Name
5-N-[(2-methoxyphenyl)methyl]-2-phenyl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
    Show/Hide
PubChem ID
CID: 145962355
Canonical SMILES
COc1ccccc1CNc1nc(N)c2nc(sc2n1)-c1ccccc1
    Show/Hide
Compound Formula C19H17N5OS
Compound Structure
Protein Name
Adenosine receptor A2a
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P29274
Gene Name
ADORA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 5.34 nM
   TI
   LI
   LO
   TS
2
IC50 = 7.63 nM
   TI
   LI
   LO
   TS
3
Ki = 4.72 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.72 nM