Brief Information of the Compound and Protein
Compound Name
2-thiophen-2-yl-5-N-(thiophen-2-ylmethyl)-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
    Show/Hide
PubChem ID
CID: 145954098
Canonical SMILES
Nc1nc(NCc2cccs2)nc2sc(nc12)-c1cccs1
    Show/Hide
Compound Formula C14H11N5S3
Compound Structure
Protein Name
Adenosine receptor A2a
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P29274
Gene Name
ADORA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 13.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 17.6 nM
   TI
   LI
   LO
   TS
3
Ki = 10.1 nM
   TI
   LI
   LO
   TS