Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1,3-dipropyl-8-cyclopentylxanthine
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 PubChem ID
CID: 1329
SID: 12014525
Canonical SMILES
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1
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Compound Formula C16H24N4O2
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A2a
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P29274
Gene Name
ADORA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  7
1
IC50 = 132 nM
   TI
   LI
   LO
   TS
2
Ki = 97 nM
   TI
   LI
   LO
   TS
3
Ki = 129 nM
   TI
   LI
   LO
   TS
4
Ki = 130 nM
   TI
   LI
   LO
   TS
5
Ki = 260 nM
   TI
   LI
   LO
   TS
6
Ki = 260.3 nM
   TI
   LI
   LO
   TS
7
Ki = 337 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
Ki = 226 nM
   TI
   LI
   LO
   TS
2
Ki = 291 nM
   TI
   LI
   LO
   TS
3
Ki = 788 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 261 nM
   TI
   LI
   LO
   TS
2
Ki = 56 nM
   TI
   LI
   LO
   TS
3
Ki = 129 nM
   TI
   LI
   LO
   TS
4
Ki = 130 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 157 nM
   TI
   LI
   LO
   TS
2
Ki = 260 nM
   TI
   LI
   LO
   TS