General Information of the Compound
Compound ID
CP0058054
Compound Name
N-(6-amino-1-oxo-2-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-yl)acetamide
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Structure
Formula
C17H14N6O2
Molecular Weight
334.339
Canonical SMILES
CC(=O)Nc1nc2c(N)cccc2n2c1nn(-c1ccccc1)c2=O
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InChI
InChI=1S/C17H14N6O2/c1-10(24)19-15-16-21-23(11-6-3-2-4-7-11)17(25)22(16)13-9-5-8-12(18)14(13)20-15/h2-9H,18H2,1H3,(H,19,20,24)
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InChIKey
KTKFGKLOHICPDE-UHFFFAOYSA-N
Physicochemical Property
logP
1.574
Rotatable Bonds
2
Heavy Atom Count
25
Polar Areas
107.31
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11660022
SID: 16763669
ChEMBL ID
CHEMBL378514
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 367 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 48 nM
   TI
   LI
   LO
   TS