Brief Information of the Compound and Protein
Compound Name
5-N-[(2-methoxyphenyl)methyl]-2-thiophen-2-yl-[1,3]thiazolo[5,4-d]pyrimidine-5,7-diamine
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PubChem ID
CID: 145958464
Canonical SMILES
COc1ccccc1CNc1nc(N)c2nc(sc2n1)-c1cccs1
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Compound Formula C17H15N5OS2
Compound Structure
Protein Name
Adenosine receptor A2a
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Nucleotide-like receptor (family A GPCR)
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Adenosine receptor
Uniprot ID
P29274
Gene Name
ADORA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 3.36 nM
   TI
   LI
   LO
   TS
2
IC50 = 4.41 nM
   TI
   LI
   LO
   TS
3
Ki = 2.24 nM
   TI
   LI
   LO
   TS