General Information of the Compound
Compound ID
CP0514625
Compound Name
ethyl 4-[2-[7-amino-4-(furan-2-yl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-10-yl]ethyl]benzoate
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Structure
Formula
C21H19N7O3
Molecular Weight
417.429
Canonical SMILES
CCOC(=O)c1ccc(CCn2ncc3c2nc(N)n2nc(nc32)-c2ccco2)cc1
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InChI
InChI=1S/C21H19N7O3/c1-2-30-20(29)14-7-5-13(6-8-14)9-10-27-18-15(12-23-27)19-24-17(16-4-3-11-31-16)26-28(19)21(22)25-18/h3-8,11-12H,2,9-10H2,1H3,(H2,22,25)
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InChIKey
KYOMRUOJDCTMFN-UHFFFAOYSA-N
Physicochemical Property
logP
2.7356
Rotatable Bonds
6
Heavy Atom Count
31
Polar Areas
126.36
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
10
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45482470
ChEMBL ID
CHEMBL576955
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS