| Compound ID |
Compound Name |
Compound Formula |
|
CP0681805
|
(R)-2-[(Benzylamino)methyl]chroman-7-ol oxalate
Show/Hide
|
C19H21NO6
|
1
|
| 1 |
EC50 = 0.01995 nM
|
|
|
|
CP0854346
|
(R)-2-[(3-Iodobenzylamino)methyl]chroman-7-ol oxalate
Show/Hide
|
C19H20INO6
|
1
|
| 1 |
EC50 = 0.03162 nM
|
|
|
|
CP0823240
|
(R)-2-[(Hexylamino)methyl]chroman-7-ol oxalate
Show/Hide
|
C18H27NO6
|
1
|
| 1 |
EC50 = 0.05012 nM
|
|
|
|
CP0387296
|
5-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H31N3O3
|
7
|
| 1 |
EC50 = 0.11 nM
|
|
|
| 2 |
EC50 = 0.39 nM
|
|
|
| 3 |
EC50 = 0.71 nM
|
|
|
| 4 |
EC50 = 0.74 nM
|
|
|
| 5 |
EC50 = 2.9 nM
|
|
|
| 6 |
EC50 = 12.4 nM
|
|
|
| 7 |
EC50 = 12.5 nM
|
|
|
|
CP0393754
|
(6S)-6-[propyl(4-pyrazolo[1,5-a]pyridin-6-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
8
|
| 1 |
EC50 = 0.11 nM
|
|
|
| 2 |
EC50 = 0.13 nM
|
|
|
| 3 |
EC50 = 0.3 nM
|
|
|
| 4 |
EC50 = 0.61 nM
|
|
|
| 5 |
EC50 = 0.81 nM
|
|
|
| 6 |
EC50 = 3 nM
|
|
|
| 7 |
EC50 = 13.7 nM
|
|
|
| 8 |
EC50 = 15.9 nM
|
|
|
|
CP0387293
|
6-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H31N3O3
|
8
|
| 1 |
EC50 = 0.12 nM
|
|
|
| 2 |
EC50 = 0.13 nM
|
|
|
| 3 |
EC50 = 0.31 nM
|
|
|
| 4 |
EC50 = 0.54 nM
|
|
|
| 5 |
EC50 = 0.72 nM
|
|
|
| 6 |
EC50 = 3 nM
|
|
|
| 7 |
EC50 = 13.4 nM
|
|
|
| 8 |
EC50 = 17.7 nM
|
|
|
|
CP0387645
|
(6S)-6-[propyl(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
7
|
| 1 |
EC50 = 0.12 nM
|
|
|
| 2 |
EC50 = 0.3 nM
|
|
|
| 3 |
EC50 = 0.65 nM
|
|
|
| 4 |
EC50 = 0.8 nM
|
|
|
| 5 |
EC50 = 1.3 nM
|
|
|
| 6 |
EC50 = 10.5 nM
|
|
|
| 7 |
EC50 = 14.5 nM
|
|
|
|
CP0849300
|
(R)-1-(4-(2-Fluoroethoxy)phenyl)-4-(4-(7-hydroxychroman-2-yl)-3-azabutyl)-piperazine oxalate
Show/Hide
|
C26H34FN3O7
|
1
|
| 1 |
EC50 = 0.1585 nM
|
|
|
|
CP0387262
|
(6S)-6-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-6-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H32N4O3
|
8
|
| 1 |
EC50 = 0.16 nM
|
|
|
| 2 |
EC50 = 0.19 nM
|
|
|
| 3 |
EC50 = 0.39 nM
|
|
|
| 4 |
EC50 = 0.6 nM
|
|
|
| 5 |
EC50 = 0.94 nM
|
|
|
| 6 |
EC50 = 1.5 nM
|
|
|
| 7 |
EC50 = 12.1 nM
|
|
|
| 8 |
EC50 = 13.1 nM
|
|
|
|
CP0387642
|
(6S)-6-[4-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H32N4O3
|
8
|
| 1 |
EC50 = 0.17 nM
|
|
|
| 2 |
EC50 = 0.21 nM
|
|
|
| 3 |
EC50 = 0.49 nM
|
|
|
| 4 |
EC50 = 0.67 nM
|
|
|
| 5 |
EC50 = 0.96 nM
|
|
|
| 6 |
EC50 = 1.7 nM
|
|
|
| 7 |
EC50 = 11.9 nM
|
|
|
| 8 |
EC50 = 13.2 nM
|
|
|
|
CP0240206
|
N-[4-[methyl-[(10R)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H27N5O2
|
6
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
EC50 = 1.1 nM
|
|
|
| 3 |
EC50 = 124.7 nM
|
|
|
| 4 |
EC50 = 154.5 nM
|
|
|
| 5 |
Ki = 5.78 nM
|
|
|
| 6 |
Ki = 4230 nM
|
|
|
|
CP0849299
|
(R)-2-[(4-(4-Fluorobutoxy)benzylamino)methyl]chroman-7-ol oxalate
Show/Hide
|
C23H28FNO7
|
1
|
| 1 |
EC50 = 0.3981 nM
|
|
|
|
CP0653714
|
SID50106387
Show/Hide
|
C8H12ClNO2
|
3
|
| 1 |
EC50 = 0.631 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
| 3 |
IC50 = 100000 nM
|
|
|
|
CP0866964
|
(R)-2-[(4-Iodobenzylamino)methyl]chroman-7-ol oxalate
Show/Hide
|
C19H20INO6
|
1
|
| 1 |
EC50 = 0.631 nM
|
|
|
|
CP0036921
|
3-HYDROXYTYRAMINE HYDROCHLORIDE
Show/Hide
|
C8H11NO2
|
17
|
| 1 |
EC50 = 0.67 nM
|
|
|
| 2 |
EC50 = 0.78 nM
|
|
|
| 3 |
EC50 = 0.8 nM
|
|
|
| 4 |
EC50 = 2.8 nM
|
|
|
| 5 |
EC50 = 3.9 nM
|
|
|
| 6 |
EC50 = 4.5 nM
|
|
|
| 7 |
EC50 = 18 nM
|
|
|
| 8 |
EC50 = 19 nM
|
|
|
| 9 |
EC50 = 156 nM
|
|
|
| 10 |
EC50 = 163 nM
|
|
|
| 11 |
EC50 = 226 nM
|
|
|
| 12 |
Ki = 2.9 nM
|
|
|
| 13 |
Ki = 8.73 nM
|
|
|
| 14 |
Ki = 16 nM
|
|
|
| 15 |
Ki = 260 nM
|
|
|
| 16 |
Ki = 2100 nM
|
|
|
| 17 |
Ki = 3690 nM
|
|
|
|
CP0393847
|
(10R)-10-(dipropylamino)-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C19H29N3O
|
9
|
| 1 |
EC50 = 0.9 nM
|
|
|
| 2 |
EC50 = 1 nM
|
|
|
| 3 |
EC50 = 16.8 nM
|
|
|
| 4 |
EC50 = 20.5 nM
|
|
|
| 5 |
IC50 = 98.9 nM
|
|
|
| 6 |
IC50 = 157.8 nM
|
|
|
| 7 |
IC50 = 931.1 nM
|
|
|
| 8 |
Ki = 2.59 nM
|
|
|
| 9 |
Ki = 146 nM
|
|
|
|
CP0006107
|
CAS_85760-74-3
Show/Hide
|
C13H21N3
|
26
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 = 1.3 nM
|
|
|
| 3 |
EC50 = 1.6 nM
|
|
|
| 4 |
EC50 = 3 nM
|
|
|
| 5 |
EC50 = 5.1 nM
|
|
|
| 6 |
EC50 = 5.9 nM
|
|
|
| 7 |
EC50 = 10.9 nM
|
|
|
| 8 |
EC50 = 38.7 nM
|
|
|
| 9 |
EC50 = 51 nM
|
|
|
| 10 |
EC50 = 64 nM
|
|
|
| 11 |
EC50 = 73 nM
|
|
|
| 12 |
EC50 = 83 nM
|
|
|
| 13 |
EC50 = 86 nM
|
|
|
| 14 |
EC50 = 147.6 nM
|
|
|
| 15 |
EC50 = 151 nM
|
|
|
| 16 |
EC50 = 240 nM
|
|
|
| 17 |
EC50 = 295 nM
|
|
|
| 18 |
EC50 = 353.2 nM
|
|
|
| 19 |
EC50 = 360 nM
|
|
|
| 20 |
EC50 = 616.6 nM
|
|
|
| 21 |
EC50 = 1621.81 nM
|
|
|
| 22 |
EC50 = 2300 nM
|
|
|
| 23 |
EC50 = 2800 nM
|
|
|
| 24 |
Ki = 5.56 nM
|
|
|
| 25 |
Ki = 13.1 nM
|
|
|
| 26 |
Ki = 2950 nM
|
|
|
|
CP0395266
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(2S)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C34H49N5O4
|
5
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
EC50 = 2.1 nM
|
|
|
| 3 |
EC50 = 2.9 nM
|
|
|
| 4 |
EC50 = 3.1 nM
|
|
|
| 5 |
EC50 = 4 nM
|
|
|
|
CP0387634
|
(6R)-6-[propyl(4-pyrazolo[1,5-a]pyridin-5-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
8
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
EC50 = 1.7 nM
|
|
|
| 3 |
EC50 = 5.2 nM
|
|
|
| 4 |
EC50 = 8.4 nM
|
|
|
| 5 |
EC50 = 9.8 nM
|
|
|
| 6 |
EC50 = 48 nM
|
|
|
| 7 |
EC50 = 54 nM
|
|
|
| 8 |
EC50 = 161 nM
|
|
|
|
CP0405801
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine
Show/Hide
|
C22H28N4O2
|
5
|
| 1 |
EC50 = 1.5 nM
|
|
|
| 2 |
EC50 = 1.9 nM
|
|
|
| 3 |
EC50 = 2.1 nM
|
|
|
| 4 |
EC50 = 4.4 nM
|
|
|
| 5 |
EC50 = 5 nM
|
|
|
|
CP0854344
|
(R)-1-(4-Iodophenyl)-4-(4-(7-hydroxychroman-2-yl)-3-azabutyl)-piperazine oxalate
Show/Hide
|
C24H30IN3O6
|
1
|
| 1 |
EC50 = 1.585 nM
|
|
|
|
CP0405798
|
(6R)-6-[propyl(4-pyrazolo[1,5-a]pyridin-6-yloxybutyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C24H31N3O2
|
8
|
| 1 |
EC50 = 1.7 nM
|
|
|
| 2 |
EC50 = 2.2 nM
|
|
|
| 3 |
EC50 = 5.5 nM
|
|
|
| 4 |
EC50 = 8.7 nM
|
|
|
| 5 |
EC50 = 9.6 nM
|
|
|
| 6 |
EC50 = 61 nM
|
|
|
| 7 |
EC50 = 98 nM
|
|
|
| 8 |
EC50 = 218 nM
|
|
|
|
CP0042751
|
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
Show/Hide
|
C17H17NO2
|
10
|
| 1 |
EC50 = 1.8 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
| 3 |
EC50 = 5.8 nM
|
|
|
| 4 |
Ki = 0.62 nM
|
|
|
| 5 |
Ki = 3.6 nM
|
|
|
| 6 |
Ki = 42 nM
|
|
|
| 7 |
Ki = 50 nM
|
|
|
| 8 |
Ki = 53 nM
|
|
|
| 9 |
Ki = 98 nM
|
|
|
| 10 |
Ki = 244 nM
|
|
|
|
CP0042468
|
4-Hydroxy-7-{2-[2-(3-phenethyloxy-propane-1-sulfonyl)-ethylamino]-ethyl}-3H-benzothiazol-2-one
Show/Hide
|
C22H28N2O5S2
|
1
|
| 1 |
EC50 = 1.995 nM
|
|
|
|
CP0401110
|
5-hydroxy-8-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O5
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
EC50 = 1100 nM
|
|
|
|
CP0393750
|
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H28N4O3
|
4
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
EC50 = 4.2 nM
|
|
|
| 3 |
EC50 = 7.7 nM
|
|
|
| 4 |
EC50 = 10.1 nM
|
|
|
|
CP0845763
|
1-(4-Hydroxybenzyl)-apomorphine Hydrochloride
Show/Hide
|
C24H24ClNO3
|
2
|
| 1 |
EC50 = 2.7 nM
|
|
|
| 2 |
Ki = 47 nM
|
|
|
|
CP0386863
|
(NE)-N-[[6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-3-yl]methylidene]hydroxylamine
Show/Hide
|
C23H29N5O3
|
5
|
| 1 |
EC50 = 2.9 nM
|
|
|
| 2 |
EC50 = 4.3 nM
|
|
|
| 3 |
EC50 = 6.8 nM
|
|
|
| 4 |
EC50 = 10.7 nM
|
|
|
| 5 |
EC50 = 13.1 nM
|
|
|
|
CP0393849
|
(10R)-10-[methyl-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]amino]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C24H28N4O3
|
6
|
| 1 |
EC50 = 3.1 nM
|
|
|
| 2 |
EC50 = 74 nM
|
|
|
| 3 |
EC50 = 157.8 nM
|
|
|
| 4 |
EC50 = 188.8 nM
|
|
|
| 5 |
IC50 > 5000 nM
|
|
|
| 6 |
Ki = 40.1 nM
|
|
|
|
CP0555516
|
N-[4-[1-[2-[2-[2-[2-[2-[2-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]butyl]-N-propyl-2,3-dihydro-1H-inden-2-amine
Show/Hide
|
C48H74N8O5
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0848870
|
1-(Hydroxymethyl)-apomorphine Hydrochloride
Show/Hide
|
C18H20ClNO3
|
2
|
| 1 |
EC50 = 3.4 nM
|
|
|
| 2 |
Ki = 43 nM
|
|
|
|
CP0560742
|
N-hex-5-ynyl-N-propyl-2,3-dihydro-1H-inden-2-amine
Show/Hide
|
C18H25N
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0118796
|
Cariprazine
Show/Hide
|
C21H32Cl2N4O
|
3
|
| 1 |
EC50 = 3.467 nM
|
|
|
| 2 |
Ki = 0.49 nM
|
|
|
| 3 |
Ki = 0.5012 nM
|
|
|
|
CP0042927
|
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C23H27Cl2N3O2
|
17
|
| 1 |
EC50 = 4.8 nM
|
|
|
| 2 |
EC50 = 8.7 nM
|
|
|
| 3 |
EC50 = 14.9 nM
|
|
|
| 4 |
EC50 = 17.5 nM
|
|
|
| 5 |
EC50 = 19.4 nM
|
|
|
| 6 |
EC50 = 38.9 nM
|
|
|
| 7 |
EC50 = 158.49 nM
|
|
|
| 8 |
EC50 > 5000 nM
|
|
|
| 9 |
Ki = 0.3 nM
|
|
|
| 10 |
Ki = 0.34 nM
|
|
|
| 11 |
Ki = 0.343 nM
|
|
|
| 12 |
Ki = 0.48 nM
|
|
|
| 13 |
Ki = 0.8 nM
|
|
|
| 14 |
Ki = 2.6 nM
|
|
|
| 15 |
Ki = 2.8 nM
|
|
|
| 16 |
Ki = 3.1 nM
|
|
|
| 17 |
Ki = 4.5 nM
|
|
|
|
CP0860429
|
1-Methylapomorphine Hydrochloride
Show/Hide
|
C18H20ClNO2
|
2
|
| 1 |
EC50 = 5.1 nM
|
|
|
| 2 |
Ki = 54 nM
|
|
|
|
CP0393756
|
(NE)-N-[[5-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridin-3-yl]methylidene]hydroxylamine
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
EC50 = 6.2 nM
|
|
|
|
CP0565806
|
N-[4-[1-[2-[2-[2-[2-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]butyl]-N-propyl-2,3-dihydro-1H-inden-2-amine
Show/Hide
|
C44H66N8O3
|
1
|
| 1 |
EC50 = 7.2 nM
|
|
|
|
CP0419868
|
5-hydroxy-8-[(1S)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
2
|
| 1 |
EC50 = 7.3 nM
|
|
|
| 2 |
EC50 = 8800 nM
|
|
|
|
CP0084819
|
(R)-5-Propylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
Show/Hide
|
C13H17N3O
|
6
|
| 1 |
EC50 = 9.1 nM
|
|
|
| 2 |
EC50 = 17.1 nM
|
|
|
| 3 |
EC50 = 111.2 nM
|
|
|
| 4 |
EC50 = 121.9 nM
|
|
|
| 5 |
Ki = 2.78 nM
|
|
|
| 6 |
Ki = 2430 nM
|
|
|
|
CP0574171
|
N-[4-[1-[2-[2-[2-[2-[2-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]butyl]-N-propyl-2,3-dihydro-1H-inden-2-amine
Show/Hide
|
C46H70N8O4
|
1
|
| 1 |
EC50 = 9.4 nM
|
|
|
|
CP0041034
|
US8748608, 16
Show/Hide
|
C26H28Cl2N4O2
|
2
|
| 1 |
EC50 = 15.8 nM
|
|
|
| 2 |
Ki = 267 nM
|
|
|
|
CP0406353
|
N-[4-[[(1S)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
5
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
EC50 = 92 nM
|
|
|
| 3 |
EC50 = 130 nM
|
|
|
| 4 |
EC50 = 1300 nM
|
|
|
| 5 |
EC50 = 1500 nM
|
|
|
|
CP0401111
|
8-hydroxy-5-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-1H-quinolin-2-one
Show/Hide
|
C29H32N2O4
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
EC50 = 240 nM
|
|
|
|
CP0393846
|
(10R)-3-[4-(4-phenylbutoxy)butyl]-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C27H37N3O2
|
5
|
| 1 |
EC50 = 24.6 nM
|
|
|
| 2 |
EC50 = 25.6 nM
|
|
|
| 3 |
EC50 = 194.5 nM
|
|
|
| 4 |
EC50 = 196.8 nM
|
|
|
| 5 |
Ki = 37.2 nM
|
|
|
|
CP0399135
|
4-[2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO4
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0460373
|
(S)-N-(4-(4-Phenylbenzoylamino)butyl)-N-propyl-5-amino-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine
Show/Hide
|
C27H34N4O
|
2
|
| 1 |
EC50 = 26 nM
|
|
|
| 2 |
EC50 = 370 nM
|
|
|
|
CP0431629
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(3R)-6-ethynyl-3,4-dihydro-2H-pyran-3-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C31H45N5O4
|
5
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
EC50 = 52 nM
|
|
|
| 3 |
EC50 = 110 nM
|
|
|
| 4 |
EC50 = 380 nM
|
|
|
| 5 |
EC50 = 660 nM
|
|
|
|
CP0386244
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(2R)-5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C34H49N5O4
|
3
|
| 1 |
EC50 = 30 nM
|
|
|
| 2 |
EC50 = 530 nM
|
|
|
| 3 |
EC50 = 830 nM
|
|
|
|
CP0178363
|
(R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
Show/Hide
|
C11H13N3O
|
8
|
| 1 |
EC50 = 32.2 nM
|
|
|
| 2 |
EC50 = 74.8 nM
|
|
|
| 3 |
EC50 = 165 nM
|
|
|
| 4 |
EC50 = 501.2 nM
|
|
|
| 5 |
EC50 = 543.3 nM
|
|
|
| 6 |
Ki = 17.1 nM
|
|
|
| 7 |
Ki = 46.3 nM
|
|
|
| 8 |
Ki = 16300 nM
|
|
|
|
CP0847329
|
Phenyl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C21H25Cl2N3O2
|
1
|
| 1 |
EC50 = 37.6 nM
|
|
|
|
CP0857932
|
1-Benzylapomorphine Hydrochloride
Show/Hide
|
C24H24ClNO2
|
2
|
| 1 |
EC50 = 49 nM
|
|
|
| 2 |
Ki = 77 nM
|
|
|
|
CP0408435
|
5-[4-[4-(8-hydroxy-2-oxo-1H-quinolin-5-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C25H27N5O4
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0447260
|
N-[4-[(10R)-10-(dipropylamino)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-3-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C29H37N5O2
|
9
|
| 1 |
EC50 = 53.8 nM
|
|
|
| 2 |
EC50 = 56.9 nM
|
|
|
| 3 |
EC50 = 184.9 nM
|
|
|
| 4 |
EC50 = 269.8 nM
|
|
|
| 5 |
IC50 = 712.9 nM
|
|
|
| 6 |
IC50 = 2013.7 nM
|
|
|
| 7 |
IC50 = 3647.5 nM
|
|
|
| 8 |
IC50 > 5000 nM
|
|
|
| 9 |
Ki = 86.8 nM
|
|
|
|
CP0381103
|
N-[4-[[(1R)-4-ethynylcyclohex-3-en-1-yl]-propylamino]butyl]-4-phenylbenzamide
Show/Hide
|
C28H34N2O
|
5
|
| 1 |
EC50 = 55 nM
|
|
|
| 2 |
EC50 = 66 nM
|
|
|
| 3 |
EC50 = 140 nM
|
|
|
| 4 |
EC50 = 400 nM
|
|
|
| 5 |
EC50 = 2400 nM
|
|
|
|
CP0393445
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H24ClN3O2S
|
1
|
| 1 |
EC50 = 56 nM
|
|
|
|
CP0574172
|
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-[4-[[1-[2-[2-[2-[2-[2-[2-[4-[[4-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]phenyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]phenyl]benzamide
Show/Hide
|
C76H96N10O9
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0398933
|
N-[4-[methyl-[(10R)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C24H26N4O3
|
6
|
| 1 |
EC50 = 65.9 nM
|
|
|
| 2 |
EC50 = 78.2 nM
|
|
|
| 3 |
EC50 = 163.3 nM
|
|
|
| 4 |
EC50 = 209.9 nM
|
|
|
| 5 |
Ki = 15.5 nM
|
|
|
| 6 |
Ki = 14700 nM
|
|
|
|
CP0436910
|
5-[4-[4-(5-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H27N5O5
|
2
|
| 1 |
EC50 = 68 nM
|
|
|
| 2 |
EC50 > 1000 nM
|
|
|
|
CP0860438
|
1-(4-Hydroxynaphthylmethyl)-apomorphine Hydrochloride
Show/Hide
|
C28H26ClNO3
|
2
|
| 1 |
EC50 = 76 nM
|
|
|
| 2 |
Ki = 170 nM
|
|
|
|
CP0393856
|
(10R)-10-(methylamino)-3-[2-[2-[2-(4-phenylbutoxy)ethoxy]ethoxy]ethyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C27H37N3O4
|
6
|
| 1 |
EC50 = 88.7 nM
|
|
|
| 2 |
EC50 = 139 nM
|
|
|
| 3 |
EC50 = 279.3 nM
|
|
|
| 4 |
EC50 = 677.6 nM
|
|
|
| 5 |
IC50 > 5000 nM
|
|
|
| 6 |
Ki = 34.7 nM
|
|
|
|
CP0078778
|
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
Show/Hide
|
C16H24N2O
|
2
|
| 1 |
EC50 = 89 nM
|
|
|
| 2 |
EC50 = 330 nM
|
|
|
|
CP0406354
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[[(3S)-6-ethynyl-3,4-dihydro-2H-pyran-3-yl]-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C31H45N5O4
|
5
|
| 1 |
EC50 = 90 nM
|
|
|
| 2 |
EC50 = 410 nM
|
|
|
| 3 |
EC50 = 480 nM
|
|
|
| 4 |
EC50 = 1900 nM
|
|
|
| 5 |
EC50 = 2900 nM
|
|
|
|
CP0049308
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C26H28Cl2N4O
|
2
|
| 1 |
EC50 = 92 nM
|
|
|
| 2 |
Ki = 24.8 nM
|
|
|
|
CP0401112
|
5-hydroxy-8-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C28H32N2O6
|
2
|
| 1 |
EC50 = 98 nM
|
|
|
| 2 |
EC50 = 13000 nM
|
|
|
|
CP0432721
|
(10R)-10-(methylamino)-3-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C24H28N4O3
|
7
|
| 1 |
EC50 = 104.5 nM
|
|
|
| 2 |
EC50 = 255.3 nM
|
|
|
| 3 |
EC50 = 712.9 nM
|
|
|
| 4 |
EC50 = 1499.7 nM
|
|
|
| 5 |
IC50 = 4102 nM
|
|
|
| 6 |
IC50 > 5000 nM
|
|
|
| 7 |
Ki = 338 nM
|
|
|
|
CP0399133
|
4-[2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO4
|
2
|
| 1 |
EC50 = 110 nM
|
|
|
| 2 |
EC50 = 2600 nM
|
|
|
|
CP0436908
|
5-hydroxy-8-[4-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl]piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Show/Hide
|
C24H28N6O5
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0224357
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C27H32N4O2
|
3
|
| 1 |
EC50 = 114 nM
|
|
|
| 2 |
IC50 = 107 nM
|
|
|
| 3 |
Ki = 28.3 nM
|
|
|
|
CP0408430
|
5-hydroxy-8-(4-propylpiperazin-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
|
C15H21N3O3
|
2
|
| 1 |
EC50 = 130 nM
|
|
|
| 2 |
EC50 = 980 nM
|
|
|
|
CP0386241
|
4-[3-(1-butyltriazol-4-yl)propoxy]-N-[4-[2-(8-hydroxy-2-oxo-1H-quinolin-5-yl)ethyl-propylamino]butyl]-3-methoxybenzamide
Show/Hide
|
C35H48N6O5
|
5
|
| 1 |
EC50 = 140 nM
|
|
|
| 2 |
EC50 = 980 nM
|
|
|
| 3 |
EC50 = 1700 nM
|
|
|
| 4 |
EC50 = 3800 nM
|
|
|
| 5 |
EC50 = 7300 nM
|
|
|
|
CP0185379
|
N-[[(1S,2S)-2-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]cyclopropyl]methyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C27H28Cl2N4O
|
3
|
| 1 |
EC50 = 150 nM
|
|
|
| 2 |
IC50 = 672 nM
|
|
|
| 3 |
Ki = 53.7 nM
|
|
|
|
CP0384609
|
4-[(1R)-1-hydroxy-2-[2-(2-methoxyphenoxy)ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C17H21NO5
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0408432
|
8-[4-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl]piperazin-1-yl]-2,3-dihydro-1,4-benzodioxin-5-ol
Show/Hide
|
C24H29N5O5
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0861963
|
1-[4-(N,N-Dimethylamino)-benzyl]-apomorphine Dihydrochloride
Show/Hide
|
C26H30Cl2N2O2
|
2
|
| 1 |
EC50 = 174 nM
|
|
|
| 2 |
Ki = 79 nM
|
|
|
|
CP0413701
|
5-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H23Cl2N7O
|
2
|
| 1 |
EC50 = 190.55 nM
|
|
|
| 2 |
EC50 = 954.99 nM
|
|
|
|
CP0413705
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C22H21Cl2N7O
|
2
|
| 1 |
EC50 = 199.53 nM
|
|
|
| 2 |
EC50 = 3548.13 nM
|
|
|
|
CP0384600
|
4-[(1R)-1-hydroxy-2-[2-[3-methoxy-4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]benzene-1,2-diol
Show/Hide
|
C26H31NO5
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0065125
|
N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]-4-(1-oxidopyridin-1-ium-2-yl)benzamide
Show/Hide
|
C26H26Cl2N4O2
|
3
|
| 1 |
EC50 = 231 nM
|
|
|
| 2 |
IC50 = 22.9 nM
|
|
|
| 3 |
Ki = 25.8 nM
|
|
|
|
CP0093924
|
4-hydroxy-7-[(1R)-1-hydroxy-2-[2-[3-[[(2-methoxyphenyl)methylamino]methyl]phenyl]ethylamino]ethyl]-3H-1,3-benzothiazol-2-one
Show/Hide
|
C26H29N3O4S
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0560743
|
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-[4-[[1-[2-[2-[2-[2-[4-[[4-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]phenyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]phenyl]benzamide
Show/Hide
|
C72H88N10O7
|
1
|
| 1 |
EC50 = 292 nM
|
|
|
|
CP0408434
|
5-hydroxy-8-(4-methylpiperazin-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
|
C13H17N3O3
|
1
|
| 1 |
EC50 = 300 nM
|
|
|
|
CP0377739
|
[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-(dithiolan-3-yl)pentanoate
Show/Hide
|
C27H33NO2S2
|
2
|
| 1 |
EC50 = 320 nM
|
|
|
| 2 |
Ki = 174 nM
|
|
|
|
CP0552200
|
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-(4-prop-2-ynoxyphenyl)benzamide
Show/Hide
|
C32H36N2O2
|
1
|
| 1 |
EC50 = 321 nM
|
|
|
|
CP0393853
|
N-[4-[[(10R)-2-oxo-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]-propylamino]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C29H37N5O2
|
8
|
| 1 |
EC50 = 338.1 nM
|
|
|
| 2 |
EC50 = 458.1 nM
|
|
|
| 3 |
EC50 = 944 nM
|
|
|
| 4 |
EC50 = 1153.5 nM
|
|
|
| 5 |
IC50 = 2971.7 nM
|
|
|
| 6 |
IC50 = 4529 nM
|
|
|
| 7 |
IC50 > 5000 nM
|
|
|
| 8 |
Ki = 8.43 nM
|
|
|
|
CP0393860
|
(10R)-10-(methylamino)-3-[2-[2-(4-phenylbutoxy)ethoxy]ethyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C25H33N3O3
|
6
|
| 1 |
EC50 = 350.8 nM
|
|
|
| 2 |
EC50 = 1227.4 nM
|
|
|
| 3 |
EC50 = 1853.5 nM
|
|
|
| 4 |
EC50 = 2471.7 nM
|
|
|
| 5 |
IC50 > 5000 nM
|
|
|
| 6 |
Ki = 111 nM
|
|
|
|
CP0408279
|
(Z)-1-(4-fluorophenyl)-4-(4-pyridin-2-ylpiperazin-1-yl)butan-1-one O-methyloxime
Show/Hide
|
C20H25FN4O
|
2
|
| 1 |
EC50 = 366 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0413700
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C21H21Cl2N7
|
2
|
| 1 |
EC50 = 478.63 nM
|
|
|
| 2 |
EC50 = 1096.48 nM
|
|
|
|
CP0565430
|
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-[4-[[1-[2-[2-[2-[2-[2-[4-[[4-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]phenyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]phenyl]benzamide
Show/Hide
|
C74H92N10O8
|
1
|
| 1 |
EC50 = 542 nM
|
|
|
|
CP0413703
|
5-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C23H25N7O2
|
2
|
| 1 |
EC50 = 549.54 nM
|
|
|
| 2 |
EC50 = 4365.16 nM
|
|
|
|
CP0447259
|
(10R)-10-(methylamino)-3-[12-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]dodecyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C32H44N4O3
|
6
|
| 1 |
EC50 = 570.2 nM
|
|
|
| 2 |
EC50 = 666.8 nM
|
|
|
| 3 |
EC50 = 1458.8 nM
|
|
|
| 4 |
EC50 > 5000 nM
|
|
|
| 5 |
IC50 > 5000 nM
|
|
|
| 6 |
Ki = 284 nM
|
|
|
|
CP0413702
|
5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]pyrazolo[1,5-a]pyridine-3-carbaldehyde
Show/Hide
|
C24H25Cl2N7O
|
2
|
| 1 |
EC50 = 691.83 nM
|
|
|
| 2 |
EC50 = 1862.09 nM
|
|
|
|
CP0393850
|
(10R)-10-(methylamino)-3-[10-(4-phenylbutoxy)decyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C31H45N3O2
|
7
|
| 1 |
EC50 = 709.6 nM
|
|
|
| 2 |
EC50 = 2529.3 nM
|
|
|
| 3 |
EC50 > 5000 nM
|
|
|
| 4 |
IC50 = 801.7 nM
|
|
|
| 5 |
IC50 = 4487.5 nM
|
|
|
| 6 |
IC50 > 5000 nM
|
|
|
| 7 |
Ki = 23.8 nM
|
|
|
|
CP0444166
|
5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
|
C23H25Cl2N7
|
1
|
| 1 |
EC50 = 741.31 nM
|
|
|
|
CP0434990
|
5-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
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C23H27N7O
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1
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| 1 |
EC50 = 977.24 nM
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CP0412938
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(10R)-10-(methylamino)-3-[2-[2-[2-[2-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]ethoxy]ethoxy]ethoxy]ethyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
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C28H36N4O6
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6
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| 1 |
EC50 = 1004.6 nM
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| 2 |
EC50 = 1064.1 nM
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| 3 |
EC50 = 1870.7 nM
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| 4 |
EC50 = 3981.1 nM
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| 5 |
IC50 > 5000 nM
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| 6 |
Ki = 306 nM
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CP0389291
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5-hydroxy-8-(4-propyl-1,4-diazepan-1-yl)-4H-1,4-benzoxazin-3-one
Show/Hide
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C16H23N3O3
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1
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| 1 |
EC50 = 1100 nM
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CP0413704
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5-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]triazol-1-yl]pyrazolo[1,5-a]pyridine
Show/Hide
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C22H23Cl2N7
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1
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| 1 |
EC50 = 1122.02 nM
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CP0847327
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(4-carbamoyl-1-naphthyl)-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
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C26H29Cl3N4O3
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1
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| 1 |
EC50 = 2600 nM
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CP0848403
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2,3-dihydro-1,4-benzodioxin-5-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
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C23H28Cl3N3O4
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1
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| 1 |
EC50 = 3500 nM
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CP0885395
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1-naphthyl N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]carbamate
Show/Hide
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C25H29N3O3
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1
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| 1 |
EC50 = 4100 nM
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CP0904711
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1-naphthyl N-[4-[4-(o-tolyl)piperazin-1-yl]butyl]carbamate hydrochloride
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C26H32ClN3O2
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1
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| 1 |
EC50 = 5300 nM
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CP0847330
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1H-benzimidazol-4-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate hydrochloride
Show/Hide
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C22H26Cl3N5O2
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1
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| 1 |
EC50 = 9900 nM
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CP0437337
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2-methoxy-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)-benzamide
Show/Hide
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C21H26N2O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
Ki = 27 nM
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CP0159532
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N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
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C20H22N4O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0374846
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(Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)propan-1-one O-methyloxime
Show/Hide
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C20H26N4O
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3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 68 nM
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CP0374857
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(E)-1-phenyl-3-(4-thiazol-2-ylpiperazin-1-yl)propanon-1-one O-ethyloxime
Show/Hide
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C18H24N4OS
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3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 257 nM
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CP0374863
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1-(4-chlorophenyl)-2-methyl-3-(4-pyridin-2-ylpiperazin-1-yl)-propanon-1-one O-methyloxime
Show/Hide
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C20H25ClN4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 146 nM
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CP0374864
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2-hydroxy-1-pyridin-3-yl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C18H23N5O2
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0374886
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(Z)-1-(3,5-difluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
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C19H22F2N4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 225 nM
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CP0374887
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(E)-1-(3,5-dimethylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
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C21H28N4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0374888
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(E)-1-(3-chloro-4-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H22ClFN4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 171 nM
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CP0376146
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(E)-1-(4-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H23ClN4O
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3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 63.8 nM
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CP0379506
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2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-3,4-dihydro-2H-naphthalen-1-one O-ethyloxime
Show/Hide
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C22H28N4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0379535
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(Z)-1-(3-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H23ClN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0379536
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(Z)-1-(4-bromophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H23BrN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0379537
|
(Z)-1-(2,4-dichlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C19H22Cl2N4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0379538
|
(E)-1-(3,4-dimethylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
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C21H28N4O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 137 nM
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CP0381691
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(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H24N4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 172 nM
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CP0384404
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(Z)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
Show/Hide
|
C19H23ClN4O2
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 368 nM
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CP0384418
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(E)-1-(2-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H23ClN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0384421
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(Z)-1-(4-chlorophenyl)-2-methoxy-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
Show/Hide
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C20H25ClN4O2
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0386019
|
(E)-3-[4-(3-methylpyridin-2-yl)piperazin-1-yl]-1-phenylpropanon-1-one O-ethyloxime
Show/Hide
|
C21H28N4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0386031
|
(E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)propan-1-one O-methyloxime
Show/Hide
|
C20H26N4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 68.4 nM
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CP0390663
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2-[(E)-[1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propylidene]amino]oxyacetonitrile
Show/Hide
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C20H23N5O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 140 nM
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CP0390664
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(E)-1-(3-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23FN4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 101 nM
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CP0390665
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(Z)-1-(4-chlorophenyl)-3-(2-methyl-4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H25ClN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0390666
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(Z)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one Om-ethyloxime
Show/Hide
|
C19H24N4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0391206
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(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-ethyloxime
Show/Hide
|
C20H26N4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 128 nM
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CP0393866
|
(Z)-1-(3,4-dichlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C19H22Cl2N4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0393867
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(Z)-4-[1-methoxyimino-3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzonitrile
Show/Hide
|
C20H23N5O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 125 nM
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CP0394645
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1-(4-chlorophenyl)-2-(methoxyaminomethyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
Show/Hide
|
C21H28ClN5O2
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 164 nM
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CP0394655
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(E)-1-(4-chlorophenyl)-3-(2-methyl-4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H25ClN4O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 76.5 nM
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CP0395313
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(E)-1-(3,5-difluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C19H22F2N4O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 132 nM
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CP0395329
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(E)-1-(4-fluorophenyl)-4-(4-pyridin-2-ylpiperazin-1-yl)butan-1-one O-methyloxime
Show/Hide
|
C20H25FN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0395330
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(E)-1-(4-chlorophenyl)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H24ClN3O
|
3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 25.3 nM
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CP0395334
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(E)-2-[4-(ethoxyimino-3-phenylpropyl)piperazin-1-yl]benzonitrile
Show/Hide
|
C22H26N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0395335
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(Z)-N-ethoxy-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-imine
Show/Hide
|
C20H26N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0395336
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(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-propyloxime
Show/Hide
|
C21H28N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0395337
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(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-butyloxime
Show/Hide
|
C22H30N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0395338
|
(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-isopropyloxime
Show/Hide
|
C21H28N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0395340
|
(Z)-1-(3-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23FN4O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 46.6 nM
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CP0403315
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(E)-2-[4-(3-ethoxyimino-3-phenylpropyl)piperazin-1-yl]nicotinonitrile
Show/Hide
|
C21H25N5O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0407226
|
1-pyridin-3-yl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C18H23N5O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 1820 nM
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CP0407232
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(Z)-1-(4-chlorophenyl)-3-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)propan-1-one O-methyl-oxime
Show/Hide
|
C20H24ClN3O2
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0407233
|
(Z)-1-(4-chloro-3-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H25ClN4O
|
3
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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|
|
| 3 |
Ki = 60.9 nM
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CP0408265
|
(Z)-1-(4-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23FN4O
|
3
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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|
|
| 3 |
Ki = 221 nM
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CP0408270
|
(Z)-1-(4-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23ClN4O
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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|
|
|
CP0408371
|
(E)-1-(3-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23ClN4O
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
| 3 |
Ki = 98.7 nM
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CP0408376
|
(E)-1-(4-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23FN4O
|
3
|
| 1 |
EC50 > 10000 nM
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|
|
| 2 |
IC50 > 10000 nM
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|
|
| 3 |
Ki = 168 nM
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CP0408463
|
(E)-3-[4-(2-ethoxyphenyl)piperazin-1-yl]-1-phenylpropan-1-oneO-ethyloxime
Show/Hide
|
C23H31N3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0408464
|
(E)-4-[1-methoxyimino-3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzonitrile
Show/Hide
|
C20H23N5O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0408470
|
(Z)-1-(4-chlorophenyl)-3-(3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H24ClN3O
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
| 3 |
Ki = 19.4 nM
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CP0408471
|
(E)-1-(4-chlorophenyl)-3-(3',4',5',6'-tetrahydro-2'H-[2,3']bipyridinyl-1'-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H24ClN3O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0408472
|
(E)-1-(4-bromophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C19H23BrN4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0408474
|
(E)-1-(2,4-dichlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C19H22Cl2N4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
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|
|
CP0408475
|
(E)-1-(3,4-dichlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C19H22Cl2N4O
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3
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 64.5 nM
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CP0408476
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(E)-1-(4-chlorophenyl)-3-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4']bipyridinyl-1'-yl)propan-1-one O-methyl-oxime
Show/Hide
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C20H24ClN3O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0419599
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(E)-3-[4-(4-Methoxyphenyl)piperazin-1-yl]-1-phenylpropan-1-one O-ethyloxime
Show/Hide
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C22H29N3O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0419605
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(Z)-1-(3-chloro-4-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H22ClFN4O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0424761
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(Z)-1-(2-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
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C19H23ClN4O
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0424767
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(E)-1-(4-chlorophenyl)-2-methoxy-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
Show/Hide
|
C20H25ClN4O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0424849
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(Z)-1-(4-Fluorophenyl)-2-(4-pyridin-2-yl)ethanone O-Methyloxime
Show/Hide
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C18H21FN4O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 2530 nM
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CP0428205
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(E)-1-(4-chloro-3-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-methyloxime
Show/Hide
|
C20H25ClN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0432611
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(E)-3-[4-(3-methoxyphenyl)piperazin-1-yl]-1-phenylpropan-1-one O-ethyloxime
Show/Hide
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C22H29N3O2
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2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0432613
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(Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)propan-1-one O-methyloxime
Show/Hide
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C20H26N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0433495
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(E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)propan-1-one O-methyloxime
Show/Hide
|
C20H26N4O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 112 nM
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CP0439429
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(E)-1-(4-fluorophenyl)-2-(4-pyridin-2-yl)ethanone O-methyloxime
Show/Hide
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C18H21FN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0441840
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(E)-1-phenyl-3-(4-pyrimidin-2-ylpiperazin-1-yl)propanon-1-one-O-ethyloxime
Show/Hide
|
C19H25N5O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0453082
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(E)-1-(4-chlorophenyl)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
Show/Hide
|
C19H23ClN4O2
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 995 nM
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CP0458090
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(E)3-[4-(2-methoxyphenyl)piperazin-1-yl]-1-phenylpropan-1-one O-ethyloxime
Show/Hide
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C22H29N3O2
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0458099
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(Z)-1-(3,5-dimethylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C21H28N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0497175
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(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one O-allyloxime
Show/Hide
|
C21H26N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0501106
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1-(4-chlorophenyl)-2-isopropoxymethyl-3-(4-pyridin-2-ylpiperazin-1-yl)propanon-1-one O-methyloxime
Show/Hide
|
C23H31ClN4O2
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0502053
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(E)-1-phenyl-3-(4-phenylpiperazin-1-yl)propan-1-one O-ethyloxime
Show/Hide
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C21H27N3O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0522364
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(Z)-1-(3,4-dimethylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one O-methyloxime
Show/Hide
|
C21H28N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0845750
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(Z)-1-(4-fluorophenyl)-2-(4-pyridin-2-yl)ethanone oxime
Show/Hide
|
C17H19FN4O
|
2
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| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0846794
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(Z)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)propan-1-one oxime
Show/Hide
|
C19H24N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0846830
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(E)-1-(3,5-dimethylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one oxime
Show/Hide
|
C20H26N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0846831
|
(Z)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H22N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0848082
|
(Z)-1-(2-Chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H21ClN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0848083
|
(Z)-1-(3,5-difluorophenyl)-3-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H20F2N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0849208
|
(E)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)-propan-1-one oxime
Show/Hide
|
C19H24N4O2
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0849209
|
(E)-2-methoxy-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)-propan-1-one O-methyloxime
Show/Hide
|
C20H26N4O2
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0849239
|
(E)-1-(2-hydroxy-5-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C19H24N4O2
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0850200
|
(Z)-2-hydroxy-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)-propan-1-one oxime
Show/Hide
|
C19H24N4O2
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0850207
|
(E)-1-(4-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H21FN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0850208
|
3-[1-hydroxyimino-3-(4-pyridin-2-ylpiperazin-1-yl)propyl]-benzonitrile
Show/Hide
|
C19H21N5O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0851016
|
(E)-1-(3,5-Difluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one Oxime
Show/Hide
|
C18H20F2N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0851022
|
(E)-1-(4-fluorophenyl)-2-(4-pyridin-2-yl)ethanone oxime
Show/Hide
|
C17H19FN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0853248
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(E)-1-(4-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H21ClN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0853251
|
(E)-1-(4-fluorophenyl)-4-(4-pyridin-2-ylpiperazin-1-yl)butan-1-one oxime
Show/Hide
|
C19H23FN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0854850
|
(E)-1-(3-fluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H21FN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0854851
|
(E)-1-phenyl-3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-1-oxime
Show/Hide
|
C17H21N5O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0855412
|
(E)-1-phenyl-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H22N4O
|
3
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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| 3 |
Ki = 257 nM
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CP0856098
|
(E)-1-phenyl-3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-1-oxime
Show/Hide
|
C17H21N5O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0856105
|
(E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(o-tolyl)propan-1-one oxime
Show/Hide
|
C19H24N4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0860026
|
(E)-1-(3-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H21ClN4O
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0860027
|
(E)-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)propan-1-one oxime
Show/Hide
|
C19H24N4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
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| 2 |
IC50 > 10000 nM
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CP0861683
|
(Z)-1-(4-fluorophenyl)-4-(4-pyridin-2-ylpiperazin-1-yl)butan-1-one oxime
Show/Hide
|
C19H23FN4O
|
2
|
| 1 |
EC50 > 10000 nM
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| 2 |
IC50 > 10000 nM
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CP0862362
|
(Z)-2-[4-(3-hydroxyimino-3-phenylpropyl)piperazin-1-yl]nicotinonitrile
Show/Hide
|
C19H21N5O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
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| 2 |
IC50 > 10000 nM
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CP0862370
|
(Z)-2-methoxy-3-(4-pyridin-2-ylpiperazin-1-yl)-1-(m-tolyl)-propan-1-one O-methyloxime
Show/Hide
|
C20H26N4O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
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|
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CP0862485
|
(Z)-1-(4-fluorophenyl)-3-(4-(3-isopropoxyphenyl)piperazin-1-yl)propan-1-one O-methyl oxime
Show/Hide
|
C23H30FN3O2
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0862520
|
(E)-1-(2-chlorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C18H21ClN4O
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0862522
|
(E)-1-(2-benzyloxy-5-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C26H30N4O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
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| 2 |
IC50 > 10000 nM
|
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CP0862523
|
(E)-2-[4-(3-hydroxyimino-3-phenylpropyl)piperazin-1-yl]nicotinonitrile
Show/Hide
|
C19H21N5O
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0875445
|
(E)-1-phenyl-3-(4-thiazol-2-ylpiperazin-1-yl)propan-1-one oxime
Show/Hide
|
C16H20N4OS
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0881778
|
(E)-1-(2,4-difluorophenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)-propan-1-one oxime
Show/Hide
|
C18H20F2N4O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
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| 2 |
IC50 > 10000 nM
|
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CP0891812
|
(E)-1-(4-fluorophenyl)-3-(4-(3-isopropoxyphenyl)piperazin-1-yl)propan-1-one O-methyl oxime
Show/Hide
|
C23H30FN3O2
|
2
|
| 1 |
EC50 > 10000 nM
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|
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| 2 |
IC50 > 10000 nM
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CP0885396
|
1H-indol-4-yl N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]carbamate
Show/Hide
|
C23H26Cl2N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0848420
|
1-naphthyl N-[3-[4-(o-tolyl)piperazin-1-yl]propyl]carbamate hydrochloride
Show/Hide
|
C25H30ClN3O2
|
1
|
| 1 |
EC50 = 14000 nM
|
|
|
|
CP0393851
|
(10R)-10-(methylamino)-3-[8-(4-phenylbutoxy)octyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C29H41N3O2
|
3
|
| 1 |
EC50 > 5000 nM
|
|
|
| 2 |
IC50 > 5000 nM
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|
| 3 |
Ki = 38.7 nM
|
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CP0163132
|
(+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol
Show/Hide
|
C25H31NO
|
4
|
| 1 |
IC50 = 0.81 nM
|
|
|
| 2 |
IC50 = 1.1 nM
|
|
|
| 3 |
Ki = 0.04 nM
|
|
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| 4 |
Ki = 0.27 nM
|
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CP0556149
|
(1R,6S,8S)-6-tert-butyl-3-azapentacyclo[11.8.1.03,8.09,22.016,21]docosa-9,11,13(22),16,18,20-hexaen-6-ol
Show/Hide
|
C25H31NO
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0040671
|
8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C23H26FN3O2
|
8
|
| 1 |
IC50 = 1.27 nM
|
|
|
| 2 |
IC50 = 2.56 nM
|
|
|
| 3 |
Ki = 0.06 nM
|
|
|
| 4 |
Ki = 0.28 nM
|
|
|
| 5 |
Ki = 0.44 nM
|
|
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| 6 |
Ki = 0.5 nM
|
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| 7 |
Ki = 1.08 nM
|
|
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| 8 |
Ki = 1.2 nM
|
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|
CP0421573
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
|
C24H28FN3O4S
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0483490
|
4-chloro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
|
C24H27ClFN3O4S
|
1
|
| 1 |
IC50 = 2 nM
|
|
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|
CP0424881
|
N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)-4-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C25H27F4N3O4S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0424886
|
4-fluoro-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
|
C24H27F2N3O4S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0421575
|
4-cyano-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzenesulfonamide
Show/Hide
|
C25H27FN4O4S
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0218398
|
6-[5-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]pentanoyl]-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-11-one
Show/Hide
|
C28H30FN3O3
|
1
|
| 1 |
IC50 = 9.02 nM
|
|
|
|
CP0531998
|
N-(cyclopropylmethyl)-N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]benzamide
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C26H30FN3O2
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1
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| 1 |
IC50 = 10.8 nM
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CP0424877
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-propylbenzamide
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C25H30FN3O2
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1
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| 1 |
IC50 = 18.5 nM
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CP0046341
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8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)
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C17H18ClNO
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1
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| 1 |
IC50 = 31 nM
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CP0049309
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N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]-4-(6-oxo-1H-pyridin-2-yl)benzamide
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C26H26Cl2N4O2
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2
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| 1 |
IC50 = 41 nM
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| 2 |
Ki = 23.6 nM
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CP0424879
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-propan-2-ylbenzamide
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C25H30FN3O2
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1
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| 1 |
IC50 = 59.3 nM
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CP0061556
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N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]-4-pyridin-2-ylbenzamide
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C26H26Cl2N4O
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3
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| 1 |
IC50 = 80.9 nM
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| 2 |
Ki = 74 nM
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| 3 |
Ki = 93.3 nM
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CP0167371
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US8748608, 21
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C26H28Cl2N4O2
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2
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| 1 |
IC50 = 88.3 nM
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| 2 |
Ki = 28.4 nM
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CP0419313
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(13S)-17-methoxy-6,8-dioxa-1-azapentacyclo[11.8.0.03,11.05,9.014,19]henicosa-3,5(9),10,14,16,18-hexaen-16-ol
Show/Hide
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C19H19NO4
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3
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| 1 |
IC50 = 91.11 nM
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| 2 |
Ki = 32 nM
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| 3 |
Ki = 32.16 nM
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CP0089986
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STEPHOLIDINE
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C19H21NO4
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3
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| 1 |
IC50 = 105.41 nM
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| 2 |
Ki = 11 nM
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| 3 |
Ki = 56.17 nM
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CP0552795
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N-[3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propyl]-N-(oxetan-3-yl)benzamide
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C25H28FN3O3
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1
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| 1 |
IC50 = 156 nM
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CP0252256
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N-[(E)-4-[4-(2-methoxyphenyl)piperazin-1-yl]but-2-enyl]-4-pyridin-2-ylbenzamide
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C27H30N4O2
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2
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| 1 |
IC50 = 175 nM
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| 2 |
Ki = 69 nM
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CP0167369
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N-[(E)-4-[4-(2-methoxyphenyl)piperazin-1-yl]but-2-enyl]-9H-fluorene-2-carboxamide
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C29H31N3O2
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2
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| 1 |
IC50 = 179 nM
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| 2 |
Ki = 48.4 nM
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CP0261925
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide
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C29H33N3O2
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2
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| 1 |
IC50 = 224 nM
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| 2 |
Ki = 55.4 nM
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CP0531999
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N-(cyclopropylmethyl)-N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]benzamide
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C25H33N3O2
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1
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| 1 |
IC50 = 288.7 nM
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CP0065126
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N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]-4-(3-methylpyridin-2-yl)benzamide
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C27H28Cl2N4O
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2
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| 1 |
IC50 = 368 nM
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| 2 |
Ki = 92 nM
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CP0419584
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(13aS)-3-methoxy-9,11-dimethyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
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C20H23NO2
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3
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| 1 |
IC50 = 456.13 nM
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| 2 |
Ki = 160.99 nM
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| 3 |
Ki = 161 nM
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CP0552800
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N-(cyclopropylmethyl)-N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]benzamide
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C24H29Cl2N3O
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1
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| 1 |
IC50 = 459.2 nM
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CP0424878
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-N-propylbenzamide
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C24H33N3O2
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1
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| 1 |
IC50 = 466.9 nM
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CP0376636
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(rac)-3-(3-(4-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-1-yl)propyl)-1-o-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol
Show/Hide
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C36H46N6O3
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2
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| 1 |
IC50 = 480 nM
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| 2 |
Ki = 19.1 nM
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CP0532001
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-propylbenzamide
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C23H29Cl2N3O
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1
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| 1 |
IC50 = 484.7 nM
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CP0377500
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(13aS)-12-(hydroxymethyl)-3,9,11-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
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C21H25NO5
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3
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| 1 |
IC50 = 514.46 nM
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| 2 |
Ki = 146.99 nM
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| 3 |
Ki = 147 nM
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CP0424880
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-propan-2-ylbenzamide
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C23H29Cl2N3O
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1
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| 1 |
IC50 = 528 nM
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CP0008601
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4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
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C21H23ClFNO2
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9
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| 1 |
IC50 = 550 nM
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| 2 |
Ki = 0.85 nM
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| 3 |
Ki = 1 nM
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| 4 |
Ki = 1.1 nM
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| 5 |
Ki = 1.4 nM
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| 6 |
Ki = 1.9 nM
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| 7 |
Ki = 2 nM
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| 8 |
Ki = 4.5 nM
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| 9 |
Ki = 5.9 nM
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CP0483496
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-N-propan-2-ylbenzamide
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C24H33N3O2
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1
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| 1 |
IC50 = 823.5 nM
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CP0416645
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(13aS)-3,11-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
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C19H21NO3
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3
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| 1 |
IC50 = 873.14 nM
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| 2 |
Ki = 346.76 nM
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| 3 |
Ki = 347 nM
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CP0044469
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(1S)-16-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-17-ol
Show/Hide
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C19H19NO4
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2
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| 1 |
IC50 = 1000 nM
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| 2 |
Ki = 145 nM
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CP0416646
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(13aS)-2,3-dimethoxy-9,11-dimethyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
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C21H25NO2
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2
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| 1 |
IC50 = 1155.3 nM
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| 2 |
Ki = 223.61 nM
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CP0411956
|
US9359372, DC037012
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C19H17NO4
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2
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| 1 |
IC50 = 1239.4 nM
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| 2 |
Ki = 239.9 nM
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CP0079495
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9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
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C28H29Cl2N3O
|
3
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| 1 |
IC50 = 1280 nM
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| 2 |
Ki = 54.7 nM
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| 3 |
Ki = 112 nM
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CP0202185
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N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]-4-(6-methylpyridin-2-yl)benzamide
Show/Hide
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C27H28Cl2N4O
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2
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| 1 |
IC50 = 1300 nM
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| 2 |
Ki = 105 nM
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CP0376635
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(rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)butyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol
Show/Hide
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C37H48N6O3
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2
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| 1 |
IC50 = 1570 nM
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| 2 |
Ki = 80 nM
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CP0411955
|
US9359372, DC037008
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C21H25NO4
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2
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| 1 |
IC50 = 1727.6 nM
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| 2 |
Ki = 334.38 nM
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CP0424883
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N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]-N-(oxetan-3-yl)benzamide
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C23H27Cl2N3O2
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1
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| 1 |
IC50 = 1878 nM
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CP0411958
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US9359372, DC037013
Show/Hide
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C20H21NO4
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2
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| 1 |
IC50 = 2508.05 nM
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| 2 |
Ki = 485.43 nM
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CP0483493
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-N-(oxetan-3-yl)benzamide
Show/Hide
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C24H31N3O3
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1
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| 1 |
IC50 = 3765 nM
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CP0483491
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N-propyl-N-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]benzamide
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C22H30N4O
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1
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| 1 |
IC50 = 6935 nM
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CP0795225
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1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
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C19H16N2O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0894678
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N-(4-methoxy-3-phenethoxyphenethyl)-N-propylpropan-1-amine hydrochloride
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C23H34ClNO2
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1
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| 1 |
IC50 > 10000 nM
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CP0070454
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6-amino-3-(pyrrolidin-1-ylmethyl)chromen-2-one
Show/Hide
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C14H16N2O2
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1
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| 1 |
IC50 = 16280 nM
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CP0169939
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(-)-Corydalmine
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C20H23NO4
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2
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| 1 |
IC50 = 18730 nM
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| 2 |
Ki = 305 nM
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CP0084884
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3-(pyrrolidin-1-ylmethyl)-6-(trifluoromethoxy)chromen-2-one
Show/Hide
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C15H14F3NO3
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1
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| 1 |
IC50 > 26000 nM
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CP0072122
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3-(pyrrolidin-1-ylmethyl)-6-(trifluoromethyl)chromen-2-one
Show/Hide
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C15H14F3NO2
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1
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| 1 |
IC50 > 30000 nM
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CP0084882
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6-methoxy-3-(pyrrolidin-1-ylmethyl)chromen-2-one
Show/Hide
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C15H17NO3
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1
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| 1 |
IC50 > 30000 nM
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CP0084998
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3-(propylaminomethyl)chromen-2-one
Show/Hide
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C13H15NO2
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1
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| 1 |
IC50 > 30000 nM
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CP0084999
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6-nitro-3-(pyrrolidin-1-ylmethyl)chromen-2-one
Show/Hide
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C14H14N2O4
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1
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| 1 |
IC50 > 30000 nM
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CP0382963
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MLS001173843
Show/Hide
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C21H26N2O4
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1
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| 1 |
IC50 > 100000 nM
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CP0243806
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
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C23H24Cl2FN3O2
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4
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| 1 |
Kd = 0.03 nM
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| 2 |
Ki = 960 nM
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| 3 |
Ki = 9163 nM
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| 4 |
Ki = 14600 nM
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CP0059646
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7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one
Show/Hide
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C24H23N3O2
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2
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| 1 |
Ki = 0.04 nM
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| 2 |
Ki = 0.1 nM
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CP0887640
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7-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one oxalate
Show/Hide
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C27H32FN3O7
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1
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| 1 |
Ki = 0.07 nM
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CP0053105
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(S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide
Show/Hide
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C17H25ClN2O3
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2
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| 1 |
Ki = 0.086 nM
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| 2 |
Ki = 0.26 nM
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CP0400288
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5-(3-fluoropropyl)-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C20H29FN2O3
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1
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| 1 |
Ki = 0.097 nM
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CP0396617
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6-fluoro-3-[1-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
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C27H29FN4O3S
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1
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| 1 |
Ki = 0.1 nM
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CP0338716
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1-Chloro-2-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H20ClNO
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1
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| 1 |
Ki = 0.13 nM
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CP0337664
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8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
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C24H28FN3O2
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1
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| 1 |
Ki = 0.133 nM
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CP0913681
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7-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one oxalate
Show/Hide
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C26H31N3O7
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1
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| 1 |
Ki = 0.14 nM
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CP0219574
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3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C26H29N5O2S2
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1
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| 1 |
Ki = 0.14 nM
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CP0489687
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4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
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C27H32FN3O2S
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1
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| 1 |
Ki = 0.17 nM
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CP0847130
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7-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C26H33N3O7
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1
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| 1 |
Ki = 0.22 nM
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CP0847131
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7-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C27H34FN3O7
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1
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| 1 |
Ki = 0.26 nM
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CP0396077
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3-[4-[2-[(2R)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
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1
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| 1 |
Ki = 0.3 nM
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CP0241906
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7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one
Show/Hide
|
C25H27N3O2S
|
1
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| 1 |
Ki = 0.3 nM
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CP0195473
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1-Methyl-4-[8-(2-methyl-2H-tetrazol-5-ylmethyl)-10,11-dihydro-dibenzo[b,f]thiepin-10-yl]piperazine
Show/Hide
|
C22H26N6S
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1
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| 1 |
Ki = 0.35 nM
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CP0049047
|
(+)butaclamol
Show/Hide
|
C25H31NO
|
2
|
| 1 |
Ki = 0.37 nM
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| 2 |
Ki = 2.58 nM
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CP0277803
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C19H24Cl2N4
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1
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| 1 |
Ki = 0.4 nM
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CP0205851
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1-Methyl-4-(8-(2-methyl-2H-tetrazol-5-yl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine
Show/Hide
|
C21H24N6S
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1
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| 1 |
Ki = 0.44 nM
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CP0487359
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3-[4-[2-[(2S)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
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1
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| 1 |
Ki = 0.5 nM
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CP0040242
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16-methoxy-11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene
Show/Hide
|
C19H23NO
|
1
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| 1 |
Ki = 0.55 nM
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CP0240252
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-phenylpyridin-2-amine
Show/Hide
|
C25H28Cl2N4
|
1
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| 1 |
Ki = 0.55 nM
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CP0321301
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-5-phenylpyridin-2-amine
Show/Hide
|
C25H28Cl2N4
|
1
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| 1 |
Ki = 0.59 nM
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CP0036302
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C23H26Cl2N4
|
1
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| 1 |
Ki = 0.6 nM
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CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
1
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| 1 |
Ki = 0.6 nM
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CP0186639
|
3,11-Dimethoxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C20H25NO2
|
1
|
| 1 |
Ki = 0.62 nM
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CP0400225
|
3-(3-fluoropropyl)-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C18H25FN2O
|
1
|
| 1 |
Ki = 0.63 nM
|
|
|
|
CP0450839
|
3-[4-[2-[(2R)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0329826
|
4-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)pyridin-2-amine
Show/Hide
|
C26H29F3N4
|
1
|
| 1 |
Ki = 0.76 nM
|
|
|
|
CP0370155
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C20H28N4O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0056386
|
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
Show/Hide
|
C21H21ClN4OS
|
3
|
| 1 |
Ki = 0.8 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
| 3 |
Ki = 2.1 nM
|
|
|
|
CP0467853
|
7-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C25H32ClN3O2
|
1
|
| 1 |
Ki = 0.844 nM
|
|
|
|
CP0861004
|
4-(4-Iodophenyl)-1-((4-methoxy-1H-indol-3-yl)methyl)-piperidin-4-ol oxalate
Show/Hide
|
C23H25IN2O6
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0902372
|
4-(4-Iodophenyl)-1-((5-methoxy-1H-indol-3-yl)methyl)-piperidin-4-ol oxalate
Show/Hide
|
C23H25IN2O6
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0544829
|
4-(4-Iodophenyl)-1-((4-methoxy-1H-indol-3-yl)methyl)-piperidin-4-ol oxalate
Show/Hide
|
C21H23IN2O2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0445918
|
3-[4-[2-[(2R)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0228156
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]isoquinolin-1-amine
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0332248
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]isoquinolin-1-amine
Show/Hide
|
C24H27F3N4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0416051
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C26H29N5O2S2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0414533
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C27H33N5OS
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0530031
|
(1R,2S,6R,7S)-4-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H34N4O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0467727
|
2-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C24H31N3O4S
|
2
|
| 1 |
Ki = 1 nM
|
|
|
| 2 |
Ki = 61 nM
|
|
|
|
CP0701083
|
endo-8-(Benzofur-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H22ClNO2
|
1
|
| 1 |
Ki = 1.06 nM
|
|
|
|
CP0297520
|
5-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)pyridin-2-amine
Show/Hide
|
C26H29F3N4
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0869617
|
endo-8-(5-Fluorobenzofur-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H21ClFNO2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0371909
|
3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)quinazolin-4(3H)-one
Show/Hide
|
C23H28N4O2
|
2
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 184 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
3
|
| 1 |
Ki = 1.2 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
| 3 |
Ki = 6.1 nM
|
|
|
|
CP0036333
|
(S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide
Show/Hide
|
C15H20Cl2N2O3
|
2
|
| 1 |
Ki = 1.21 nM
|
|
|
| 2 |
Ki = 12.7 nM
|
|
|
|
CP0881590
|
endo-8-(5-Fluorobenzofur-3-ylmethyl)-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H20Cl2FNO2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0381494
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C82H122N18O20S
|
1
|
| 1 |
Ki = 1.47 nM
|
|
|
|
CP0869616
|
endo-8-(5-Methoxybenzofur-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C23H24ClNO3
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0918928
|
endo-8-(Benzofur-3-ylmethyl)-3-(4-bromophenyl)-8-azabicyclo-[3.2.1]octan-3-ol
Show/Hide
|
C22H22BrNO2
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0297521
|
N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]-4-phenylpyridin-2-amine
Show/Hide
|
C25H29FN4
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0332247
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C24H27F3N4
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0888512
|
endo-8-(Benzofur-3-ylmethyl)-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H21Cl2NO2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0390939
|
6-fluoro-3-[1-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0455867
|
CAS_441351-20-8
Show/Hide
|
C28H36N4O2S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0535496
|
7-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H34ClN3O3
|
1
|
| 1 |
Ki = 1.86 nM
|
|
|
|
CP0267433
|
1-Methyl-4-[8-(1-methyl-1H-tetrazol-5-ylmethyl)-10,11-dihydrodibenzo-[b,f]thiepin-10-yl]piperazine
Show/Hide
|
C22H26N6S
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0902370
|
8-(Benzofuran-3-ylmethyl)-3-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate
Show/Hide
|
C29H31FN6O6
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0860173
|
N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-5-methoxy-1H-indole-3-carboxamide oxalic acid
Show/Hide
|
C28H35FN4O7
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0389125
|
6-fluoro-3-[1-[2-[(2R)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperidin-4-yl]-1,2-benzoxazole
Show/Hide
|
C27H29FN4O3S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0417068
|
3-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C27H36N4O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0514794
|
2-[[4-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]phenyl]methyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C26H27N3O4S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0375780
|
N-[3-[4-(2-methylsulfanylphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
|
C22H27N5OS
|
2
|
| 1 |
Ki = 2.2 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
|
CP0162854
|
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C16H25NO
|
4
|
| 1 |
Ki = 2.27 nM
|
|
|
| 2 |
Ki = 142 nM
|
|
|
| 3 |
Ki = 143 nM
|
|
|
| 4 |
Ki = 202 nM
|
|
|
|
CP0377177
|
4-(4-bromophenyl)-1-((4-methoxy-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23BrN2O2
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0860992
|
1-(Benzofuran-3-ylmethyl)-4-(4-iodophenyl)piperidin-4-ol oxalate
Show/Hide
|
C22H22INO6
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0141367
|
1,3-Dichloro-2-methoxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C19H21Cl2NO
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0506201
|
4-(4-bromophenyl)-1-((5-methoxy-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23BrN2O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0321300
|
N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]-5-phenylpyridin-2-amine
Show/Hide
|
C25H29FN4
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0913682
|
7-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propoxy)quinolin-2(1H)-one oxalate
Show/Hide
|
C25H29N3O7
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0158026
|
1-butyl-4-(2-chloro-3-ethylphenyl)piperazine
Show/Hide
|
C16H25ClN2
|
1
|
| 1 |
Ki = 2.93 nM
|
|
|
|
CP0390937
|
3-[4-[2-[(2S)-1-quinolin-4-ylsulfonylazepan-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C28H33N5O2S2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0391297
|
3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0466249
|
4-[(2R)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0529086
|
3-[4-[2-[(2S)-1-isoquinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0036303
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinolin-1-amine
Show/Hide
|
C23H26Cl2N4
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0424070
|
1-butyl-4-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C14H20Cl2N2
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0140332
|
6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol
Show/Hide
|
C16H22INO
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0419149
|
(-)-(S)-6-(Propyl(2-(4-(quinolin-4-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
Ki = 3.74 nM
|
|
|
|
CP0375619
|
(S)-6-(propyl(2-(4-(quinolin-4-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 3.74 nM
|
|
|
|
CP0901061
|
1-((1H-Indol-3-yl)methyl)-4-(4-iodophenyl)piperidin-4-ol oxalate
Show/Hide
|
C22H23IN2O5
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0373714
|
6-Methyl-5,6,7,8,13,15-hexahydro-4H-indolo[4,3a,3-fg][3]benzazacycloundecene
Show/Hide
|
C20H22N2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
5
|
| 1 |
Ki = 4 nM
|
|
|
| 2 |
Ki = 6.1 nM
|
|
|
| 3 |
Ki = 7 nM
|
|
|
| 4 |
Ki = 9 nM
|
|
|
| 5 |
Ki = 32 nM
|
|
|
|
CP0391298
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzoxazole
Show/Hide
|
C26H29N5O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0396080
|
5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0476720
|
3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylazepan-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C28H33N5O2S2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0424210
|
2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
|
C21H25N3O3S
|
2
|
| 1 |
Ki = 4.1 nM
|
|
|
| 2 |
Ki = 38 nM
|
|
|
|
CP0504160
|
4-(4-chlorophenyl)-1-((5-methoxy-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0504457
|
4-(4-chlorophenyl)-1-((4-methoxy-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0073485
|
1-benzyl-4-(3-hydroxyphenyl)piperazine
Show/Hide
|
C17H20N2O
|
2
|
| 1 |
Ki = 4.6 nM
|
|
|
| 2 |
Ki = 115 nM
|
|
|
|
CP0913527
|
7-(4-(4-(2-Methoxy-4-methylphenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C27H35N3O7
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0561496
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-5-methylimidazo[2,1-b][1,3]thiazole-6-carboxamide
Show/Hide
|
C23H30ClN5OS
|
1
|
| 1 |
Ki = 4.65 nM
|
|
|
|
CP0127400
|
(-)-Pramipexole
Show/Hide
|
C10H17N3S
|
2
|
| 1 |
Ki = 4.7 nM
|
|
|
| 2 |
Ki = 11.1 nM
|
|
|
|
CP0059813
|
3-Chloro-2-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H20ClNO
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0406019
|
1-((1H-indol-3-yl)methyl)-4-(4-bromophenyl)piperidin-4-ol
Show/Hide
|
C20H21BrN2O
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0891096
|
7-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C25H31N3O7
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0894766
|
6-(Propyl(2-(4-(quinolin-4-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
Ki = 4.89 nM
|
|
|
|
CP0881592
|
endo-8-(Benzofur-3-ylmethyl)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H22FNO2
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0396620
|
4-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0416050
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0450842
|
5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0487358
|
3-[4-[2-[(2R)-1-quinolin-4-ylsulfonylpiperidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C27H31N5O2S2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0542762
|
2-N-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H28Cl2N8
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0860172
|
N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-1H-indole-3-carboxamide oxalic acid
Show/Hide
|
C27H33FN4O6
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0496628
|
1-(2,3-dichlorophenyl)-4-propylpiperazine
Show/Hide
|
C13H18Cl2N2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0452975
|
7-(Propyl(2-(4-(quinolin-5-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 5.22 nM
|
|
|
|
CP0455926
|
N-[4-[methyl-[(10R)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C29H30N4O2
|
2
|
| 1 |
Ki = 5.47 nM
|
|
|
| 2 |
Ki = 3700 nM
|
|
|
|
CP0409144
|
1-((5-methoxy-1H-indol-3-yl)methyl)-4-(4-(methylthio)phenyl)piperidin-4-ol
Show/Hide
|
C22H26N2O2S
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0224535
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O
|
1
|
| 1 |
Ki = 5.5 nM
|
|
|
|
CP0879780
|
endo-8-(Naphtho[1,2-b]fur-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C26H24ClNO2
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0240250
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinolin-2-amine
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
Ki = 5.6 nM
|
|
|
|
CP0424340
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C24H30ClN5O
|
1
|
| 1 |
Ki = 5.64 nM
|
|
|
|
CP0869495
|
(E)-N-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)but-2-en-1-yl)-6-methoxy-1H-indole-3-carboxamide oxalic acid
Show/Hide
|
C28H33FN4O7
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0551805
|
(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-[[(E)-[4-[ditert-butyl(fluoro)silyl]phenyl]methylideneamino]oxycarbonylamino]-2-[3-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]hexanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C104H156FN21O23SSi
|
1
|
| 1 |
Ki = 5.98 nM
|
|
|
|
CP0408251
|
4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azepan-1-yl]sulfonylisoquinoline
Show/Hide
|
C29H34N4O2S2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0415732
|
4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0165743
|
4-Chloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H20ClNO
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0371907
|
2-(4-(4-phenyl-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
|
C22H27N3O4S
|
2
|
| 1 |
Ki = 6.2 nM
|
|
|
| 2 |
Ki = 360 nM
|
|
|
|
CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0224534
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C25H30ClN3O2
|
1
|
| 1 |
Ki = 6.34 nM
|
|
|
|
CP0035955
|
(R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C16H22INO
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0912199
|
1-(Benzofuran-3-ylmethyl)-4-(4-bromophenyl)piperidin-4-ol oxalate
Show/Hide
|
C22H22BrNO6
|
1
|
| 1 |
Ki = 6.6 nM
|
|
|
|
CP0480201
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-2-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
1
|
| 1 |
Ki = 6.83 nM
|
|
|
|
CP0421766
|
1-((1H-indol-3-yl)methyl)-4-(3,4-dichlorophenyl)piperidin-4-ol
Show/Hide
|
C20H20Cl2N2O
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0396615
|
3-[4-[2-[(2R)-1-quinolin-5-ylsulfonylpiperidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
|
C27H31N5O2S2
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0317610
|
1,1-dioxo-2-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C24H28F3N3O3S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0562769
|
2-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C17H24Cl2N8
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0452974
|
7-(Propyl(2-(4-(quinolin-4-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 7.08 nM
|
|
|
|
CP0919567
|
8-(Benzofuran-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate
Show/Hide
|
C25H27N3O6
|
1
|
| 1 |
Ki = 7.1 nM
|
|
|
|
CP0871789
|
7-(5-(4-(2-Methoxyphenyl)piperazin-1-yl)pentyloxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C27H35N3O7
|
1
|
| 1 |
Ki = 7.3 nM
|
|
|
|
CP0551806
|
5-[3-[1-[6-[2-[2-[2-[2-(3-amino-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethylamino]-6-oxohexyl]-2,5-dioxopyrrolidin-3-yl]sulfanylpropyl]-2,3-dimethoxy-N-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methyl]benzamide
Show/Hide
|
C41H65N5O11S
|
1
|
| 1 |
Ki = 7.31 nM
|
|
|
|
CP0438619
|
7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-prop-2-ynyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C27H33Cl2N3O
|
1
|
| 1 |
Ki = 7.37 nM
|
|
|
|
CP0920165
|
7-(5-(4-(2-Methoxyphenyl)piperazin-1-yl)pentyloxy)quinolin-2(1H)-one oxalate
Show/Hide
|
C27H33N3O7
|
1
|
| 1 |
Ki = 7.4 nM
|
|
|
|
CP0869498
|
(E)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)but-2-en-1-yl)-5-methoxy-1H-indole-3-carboxamide oxalic acid
Show/Hide
|
C28H33FN4O7
|
1
|
| 1 |
Ki = 7.5 nM
|
|
|
|
CP0041232
|
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
Show/Hide
|
C20H21ClN2O
|
3
|
| 1 |
Ki = 7.5 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
| 3 |
Ki = 11.2 nM
|
|
|
|
CP0059821
|
1-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0860998
|
8-(Benzofuran-3-ylmethyl)-3-(2-fluoroethyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate
Show/Hide
|
C26H28FN3O6
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0433627
|
5-chloro-N-[(3S)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C22H23ClN2O3S2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0418453
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-4-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0445925
|
5-[(2R)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0429636
|
2-[6-(4-naphthalen-1-ylpiperazin-1-yl)hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C27H31N3O3S
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0571683
|
2-N-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H26Cl2N8
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0555952
|
(4S)-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]acetyl]amino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]pentanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
Show/Hide
|
C150H216N36O44S
|
1
|
| 1 |
Ki = 8.01 nM
|
|
|
|
CP0401191
|
(10R)-3-propyl-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C16H23N3O
|
2
|
| 1 |
Ki = 8.08 nM
|
|
|
| 2 |
Ki = 868 nM
|
|
|
|
CP0399204
|
(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-amino-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-5-carbamimidamido-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]pentanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]hexanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]-5-oxopentanoyl]amino]-4-oxobutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylsulfanylbutanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]hexanoic acid
Show/Hide
|
C134H209N37O26S2
|
1
|
| 1 |
Ki = 8.14 nM
|
|
|
|
CP0427965
|
N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C27H29N3OS
|
1
|
| 1 |
Ki = 8.37 nM
|
|
|
|
CP0455628
|
N-[[(1R,2R)-2-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]cyclopropyl]methyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H26Cl2N4O
|
1
|
| 1 |
Ki = 8.41 nM
|
|
|
|
CP0175178
|
11-methyl-11-aza-tricyclo[12.4.0.03,8]octadeca-1(18),3(8),4,6,14,16-hexaene
Show/Hide
|
C18H21N
|
2
|
| 1 |
Ki = 8.47 nM
|
|
|
| 2 |
Ki = 56.5 nM
|
|
|
|
CP0438793
|
7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C27H37Cl2N3O
|
1
|
| 1 |
Ki = 8.78 nM
|
|
|
|
CP0439252
|
7-((2-(4-(Naphthalen-2-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C29H37N3O
|
1
|
| 1 |
Ki = 8.85 nM
|
|
|
|
CP0418452
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-3-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0472438
|
4-[4-[2-[(2S)-1-quinolin-5-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
|
C26H29N5O4S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0429637
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C24H28N4O3S2
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0491001
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C23H28N6OS
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0568818
|
7-[4-[4-(pyridine-2-carbonyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0568318
|
2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C22H27Cl2N5O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0555052
|
2-[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-1-yl]phenol
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 9.4 nM
|
|
|
|
CP0277805
|
5-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)oxazol-2-amine
Show/Hide
|
C24H27F3N4O
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0381492
|
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-5-carbamimidamido-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoic acid
Show/Hide
|
C83H147N33O17S
|
1
|
| 1 |
Ki = 9.69 nM
|
|
|
|
CP0300588
|
6-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C16H22INO
|
1
|
| 1 |
Ki = 9.7 nM
|
|
|
|
CP0426093
|
N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]quinoline-8-sulfonamide
Show/Hide
|
C24H29N3O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0433625
|
4-fluoro-N-[(3S)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H25FN2O3S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0538829
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C24H26Cl2N4O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0390936
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azepan-1-yl]sulfonylquinoline
Show/Hide
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C29H34N4O2S2
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1
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| 1 |
Ki = 10 nM
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CP0390938
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3-[4-[2-[(2S)-1-isoquinolin-4-ylsulfonylazetidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C25H27N5O2S2
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1
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| 1 |
Ki = 10 nM
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CP0417090
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2-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
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1
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| 1 |
Ki = 10 nM
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CP0348615
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2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-hexyl]-isoindole-1,3-dione
Show/Hide
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C25H28N4O2S
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1
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| 1 |
Ki = 10 nM
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CP0569927
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2-[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C23H28Cl2N6
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1
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| 1 |
Ki = 10 nM
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CP0558934
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(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
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C71H101N17O15S
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1
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| 1 |
Ki = 10.32 nM
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CP0351947
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3-[((E)-3-Iodo-allyl)-propyl-amino]-chroman-8-ol
Show/Hide
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C15H20INO2
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1
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| 1 |
Ki = 10.8 nM
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CP0350789
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N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
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C19H25FN4
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1
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| 1 |
Ki = 11 nM
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CP0445255
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4-fluoro-N-[1-(2-phenoxyethyl)pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C18H21FN2O3S
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1
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| 1 |
Ki = 11 nM
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CP0418454
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]quinoline-7-sulfonamide
Show/Hide
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C23H26Cl2N4O2S
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1
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| 1 |
Ki = 11 nM
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CP0086335
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4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C27H30N4O2S2
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1
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| 1 |
Ki = 11 nM
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CP0396072
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5-[(2S)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C28H29ClN4O2S
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1
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| 1 |
Ki = 11 nM
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CP0415694
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3-[4-[2-[(2S)-1-quinolin-5-ylsulfonylazetidin-2-yl]ethyl]piperazin-1-yl]-1,2-benzothiazole
Show/Hide
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C25H27N5O2S2
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1
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| 1 |
Ki = 11 nM
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CP0417089
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1-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
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C29H35N3O2
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1
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| 1 |
Ki = 11 nM
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CP0409653
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(R)-5-Dipropylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one
Show/Hide
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C16H23N3O
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1
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| 1 |
Ki = 11.4 nM
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CP0847346
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endo-8-(Naphtho[2,1-b]fur-1-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
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C26H24ClNO2
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1
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| 1 |
Ki = 11.7 nM
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CP0898311
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(E)-5-Methoxy-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but-2-en-1-yl)-1H-indole-3-carboxamide oxalic acid
Show/Hide
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C27H32N4O7
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1
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| 1 |
Ki = 11.7 nM
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CP0277804
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N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
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C21H30N4
|
1
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| 1 |
Ki = 12 nM
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CP0410602
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C22H25Cl2N5O
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1
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| 1 |
Ki = 12 nM
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CP0390940
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4-[4-[2-[(2R)-1-isoquinolin-4-ylsulfonylpyrrolidin-2-yl]ethyl]piperazin-1-yl]-3H-1,3-benzoxazol-2-one
Show/Hide
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C26H29N5O4S
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1
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| 1 |
Ki = 12 nM
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CP0396618
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4-[(2R)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C28H29ClN4O2S
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1
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| 1 |
Ki = 12 nM
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CP0408250
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5-[(2R)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
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C27H32N4O4S
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1
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| 1 |
Ki = 12 nM
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CP0488182
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N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-5-methyl-1H-imidazole-2-carboxamide
Show/Hide
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C21H30ClN5O
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1
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| 1 |
Ki = 12.2 nM
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CP0434235
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(2S)-2-[[(2S,3S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-3-carboxy-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]acetyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]hexanoyl]amino]-3-methylpentanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]hexanoyl]amino]hexanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
Show/Hide
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C164H265N35O41S
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1
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| 1 |
Ki = 12.27 nM
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CP0414228
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N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
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C26H29NO4
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1
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| 1 |
Ki = 12.3 nM
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CP0919398
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1-(1-((5-Methoxy-1H-indol-3-yl)methyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one oxalate
Show/Hide
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C24H26N4O6
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1
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| 1 |
Ki = 12.5 nM
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CP0409654
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(10R)-10-[methyl(propyl)amino]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
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C14H19N3O
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2
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| 1 |
Ki = 12.5 nM
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| 2 |
Ki = 1180 nM
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CP0421285
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N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]butyl]-5-ethyl-1H-imidazole-2-carboxamide
Show/Hide
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C22H32ClN5O
|
1
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| 1 |
Ki = 12.5 nM
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CP0410554
|
2-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-1-yl]phenol
Show/Hide
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C22H27N5O2
|
1
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| 1 |
Ki = 12.8 nM
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CP0398936
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(10R)-3-butyl-10-(methylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
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C15H21N3O
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2
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| 1 |
Ki = 12.8 nM
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| 2 |
Ki = 361 nM
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CP0701087
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endo-8-(Benzothien-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
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C22H22ClNOS
|
1
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| 1 |
Ki = 12.9 nM
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CP0057834
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N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]-1H-indole-2-carboxamide
Show/Hide
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C27H30N4O
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1
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| 1 |
Ki = 12.9 nM
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CP0383395
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(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
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C85H143N23O19S2
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1
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| 1 |
Ki = 12.96 nM
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CP0100739
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazolo[1,5-a]pyridine-3-carboxamide
Show/Hide
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C22H27N5O2
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2
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| 1 |
Ki = 13 nM
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| 2 |
Ki = 83 nM
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CP0125484
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4-phenyl-N-(4-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)butyl)thiazol-2-amine
Show/Hide
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C24H27F3N4S
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1
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| 1 |
Ki = 13 nM
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CP0356699
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1-(3-chlorophenyl)-3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]urea
Show/Hide
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C22H29ClN4O2
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1
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| 1 |
Ki = 13 nM
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CP0391303
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4-[(2S)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
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C28H29ClN4O2S
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1
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| 1 |
Ki = 13 nM
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CP0396619
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5-[(2S)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H32N4O4S
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1
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| 1 |
Ki = 13 nM
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CP0542758
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2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C28H37N9O
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1
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| 1 |
Ki = 13 nM
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CP0903618
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2-(2-Fluoroethoxy)-5-iodo-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C26H31FIN3O7
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1
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| 1 |
Ki = 13.2 nM
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CP0398934
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(10R)-10-(methylamino)-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C14H19N3O
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2
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| 1 |
Ki = 13.2 nM
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| 2 |
Ki = 751 nM
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CP0847306
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5-Bromo-2-(2-fluoroethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C26H31BrFN3O7
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1
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| 1 |
Ki = 13.4 nM
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CP0419143
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7-((2-(4-(Naphthalen-1-yl)-piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
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C29H37N3O
|
1
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| 1 |
Ki = 13.5 nM
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CP0861001
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1-(1-(Benzofuran-3-ylmethyl)piperidin-4-yl)-1Hbenzo[d]imidazol-2-(3H)-one oxalate
Show/Hide
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C23H23N3O6
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1
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| 1 |
Ki = 13.6 nM
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CP0902374
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4-(4-Bromophenyl)-1-((5-(2-fluoroethoxy)-1H-indol-3-yl)-methyl)piperidin-4-ol oxalate
Show/Hide
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C24H26BrFN2O6
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1
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| 1 |
Ki = 13.8 nM
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CP0381583
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5-methoxy-N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]-1H-indole-2-carboxamide
Show/Hide
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C28H32N4O2
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1
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| 1 |
Ki = 13.8 nM
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CP0230643
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1-[4-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-3-(1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
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C29H31FN4O2
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1
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| 1 |
Ki = 14 nM
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CP0525896
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N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzamide
Show/Hide
|
C24H30N4OS
|
1
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| 1 |
Ki = 14 nM
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CP0856731
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4-(2-(2-Fluoroethoxy)ethoxy)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
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C29H39F2N3O8
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1
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| 1 |
Ki = 14.2 nM
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CP0912200
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1-(Benzofuran-2-ylmethyl)-4-(4-iodophenyl)piperidin-4-ol oxalate
Show/Hide
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C22H22INO6
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1
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| 1 |
Ki = 14.3 nM
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CP0473012
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N-[2-[(1S,2R)-2-[(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)methyl]cyclopropyl]ethyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
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C24H25N5O
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1
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| 1 |
Ki = 14.4 nM
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CP0434348
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6-[(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
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C25H33Cl2N3O
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1
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| 1 |
Ki = 14.6 nM
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CP0435435
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1-butyl-4-[2-(2-fluoroethoxy)phenyl]piperazine
Show/Hide
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C16H25FN2O
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2
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| 1 |
Ki = 14.7 nM
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| 2 |
Ki = 22.3 nM
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CP0550061
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N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]-1-benzofuran-2-carboxamide
Show/Hide
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C27H29N3O2
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1
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| 1 |
Ki = 14.8 nM
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CP0381349
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2,3-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzamide
Show/Hide
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C25H24F2N2O2
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1
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| 1 |
Ki = 15 nM
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CP0385588
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N-(cyclopropylmethyl)-3-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H35FN2O3S
|
1
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| 1 |
Ki = 15 nM
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CP0476721
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5-[(2R)-2-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H29ClN4O2S
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1
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| 1 |
Ki = 15 nM
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CP0462115
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1,1-dioxo-2-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C26H30N4O3S
|
1
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| 1 |
Ki = 15 nM
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CP0653272
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4-(Dimethylamino)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
|
C27H37FN4O6
|
1
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| 1 |
Ki = 15.1 nM
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CP0785530
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4-(2-Fluoroethoxy)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
|
C27H35F2N3O7
|
1
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| 1 |
Ki = 15.1 nM
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CP0427930
|
4-(4-chlorophenyl)-1-((2-methyl-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O
|
1
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| 1 |
Ki = 15.4 nM
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CP0396051
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2-[2-[(6,6-diphenyl-1,4-dioxan-2-yl)methylamino]ethoxy]phenol
Show/Hide
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C25H27NO4
|
1
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| 1 |
Ki = 15.49 nM
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CP0488181
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]propanamide
Show/Hide
|
C17H25Cl2N3O
|
1
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| 1 |
Ki = 15.6 nM
|
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CP0850773
|
5-Hydroxy-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C26H32N4O7
|
1
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| 1 |
Ki = 15.7 nM
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CP0045182
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N-[4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]quinoline-3-carboxamide
Show/Hide
|
C28H30N4O
|
1
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| 1 |
Ki = 15.8 nM
|
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CP0486996
|
N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C19H26N2O3S2
|
1
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| 1 |
Ki = 16 nM
|
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CP0486998
|
4-fluoro-N-[(3R)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H25FN2O3S
|
1
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| 1 |
Ki = 16 nM
|
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CP0508203
|
N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C22H24N2O3S2
|
1
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| 1 |
Ki = 16 nM
|
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CP0418456
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]quinoline-7-sulfonamide
Show/Hide
|
C22H24Cl2N4O2S
|
1
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| 1 |
Ki = 16 nM
|
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CP0403500
|
N-(cyclopropylmethyl)-1-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C27H34N4O3S
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0396076
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0422317
|
1-[4-[4-(1H-indol-3-yl)piperidin-1-yl]butyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C30H34N4O3
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0473056
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1,3-benzoxazol-2-one
Show/Hide
|
C24H28N4O2S
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0484413
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-1H-benzimidazol-2-one
Show/Hide
|
C24H29N5OS
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0424341
|
N-[(E)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]but-2-enyl]-5-methyl-1H-imidazole-2-carboxamide
Show/Hide
|
C21H28ClN5O
|
1
|
| 1 |
Ki = 16.1 nM
|
|
|
|
CP0321299
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C20H25F3N4
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0418455
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-3-sulfonamide
Show/Hide
|
C23H26Cl2N4O2S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0548405
|
2-[5-[4-(2,3-dichlorophenyl)piperazin-1-yl]pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C22H25Cl2N3O3S
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0902371
|
1-(Benzofuran-2-ylmethyl)-4-(4-bromophenyl)piperidin-4-ol oxalate
Show/Hide
|
C22H22BrNO6
|
1
|
| 1 |
Ki = 17.3 nM
|
|
|
|
CP0082770
|
(-)-3-(1-Propyl-piperidin-3-yl)-phenol
Show/Hide
|
C14H21NO
|
2
|
| 1 |
Ki = 17.4 nM
|
|
|
| 2 |
Ki = 2268 nM
|
|
|
|
CP0853848
|
3-hydroxy-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine hydrobromide
Show/Hide
|
C18H22BrNO
|
2
|
| 1 |
Ki = 17.5 nM
|
|
|
| 2 |
Ki = 33.5 nM
|
|
|
|
CP0722004
|
4-(2-Fluoroethyl)-N-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C27H33F2N3O6
|
1
|
| 1 |
Ki = 17.7 nM
|
|
|
|
CP0410571
|
5-[4-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]triazol-1-yl]isoquinoline
Show/Hide
|
C27H32N6O
|
1
|
| 1 |
Ki = 17.7 nM
|
|
|
|
CP0857036
|
2-(2-Fluoroethoxy)-5-methyl-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C27H34FN3O7
|
1
|
| 1 |
Ki = 17.8 nM
|
|
|
|
CP0381351
|
2,5-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H24F2N2O3S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0429858
|
N-(cyclopropylmethyl)-1-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C24H36N4O3S
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0526780
|
3-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0545006
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C26H33ClN4O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0508464
|
N-[4-[(10R)-2-oxo-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-3-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H31N5O2
|
1
|
| 1 |
Ki = 18.5 nM
|
|
|
|
CP0082972
|
11-methyl-11,21-diazatetracyclo[12.7.0.0^{3,8}.0^{15,20}]henicosa-1(14),3(8),4,6,15,17,19-heptaene
Show/Hide
|
C20H22N2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0099064
|
3,11-Dihydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0155138
|
2-Hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0386823
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0396073
|
4-[(2S)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H32N4O4S
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0394125
|
3-(5-fluoro-1H-indol-3-yl)-1-[4-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C29H30F2N4O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0410572
|
1-(2-methoxyphenyl)-4-[5-(1-phenyltriazol-4-yl)pentyl]piperazine
Show/Hide
|
C24H31N5O
|
1
|
| 1 |
Ki = 19.4 nM
|
|
|
|
CP0396214
|
N-[[(1R,2R)-2-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]cyclopropyl]methyl]quinoline-4-carboxamide
Show/Hide
|
C25H26Cl2N4O
|
1
|
| 1 |
Ki = 19.9 nM
|
|
|
|
CP0445257
|
5-chloro-N-[(3R)-1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C19H25ClN2O3S2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0385589
|
N-(cyclopropylmethyl)-4-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H35FN2O3S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0394123
|
3-(5-fluoro-1H-indol-3-yl)-1-[4-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C30H33FN4O3
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0540390
|
2-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H29N3O4S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0548407
|
2-[5-(4-naphthalen-1-ylpiperazin-1-yl)pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C26H29N3O3S
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0568014
|
2-N-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C20H32N8O
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0053493
|
(+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3
|
2
|
| 1 |
Ki = 20.5 nM
|
|
|
| 2 |
Ki = 28 nM
|
|
|
|
CP0266478
|
1-Butyl-4-(2-methoxy-phenyl)-piperazine
Show/Hide
|
C15H24N2O
|
1
|
| 1 |
Ki = 20.6 nM
|
|
|
|
CP0890281
|
4-(2-(2-Fluoroethoxy)ethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
|
C28H38FN3O8
|
1
|
| 1 |
Ki = 20.9 nM
|
|
|
|
CP0409143
|
1-(benzofuran-3-ylmethyl)-4-(3,4-dichlorophenyl)piperidin-4-ol
Show/Hide
|
C20H19Cl2NO2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0449024
|
1-(benzofuran-3-ylmethyl)-4-(4-chlorophenyl)piperidin-4-ol
Show/Hide
|
C20H20ClNO2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0445915
|
5-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C28H32N4O2S2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0129619
|
N-[3-[2-[[(6S)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
|
C27H34N4O2S
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0059815
|
2-methoxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 21.1 nM
|
|
|
|
CP0857031
|
4-(2-Fluoroethyl)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)-butyl)benzamide oxalic acid salt
Show/Hide
|
C27H35F2N3O6
|
1
|
| 1 |
Ki = 21.4 nM
|
|
|
|
CP0558933
|
(2S)-5-amino-2-[[(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-5-carbamimidamido-2-[[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]acetyl]amino]pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid
Show/Hide
|
C100H172N38O22S
|
1
|
| 1 |
Ki = 21.47 nM
|
|
|
|
CP0434349
|
6-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalene-2,3-diol
Show/Hide
|
C27H39N3O2
|
1
|
| 1 |
Ki = 21.7 nM
|
|
|
|
CP0452360
|
7-((2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
Ki = 21.7 nM
|
|
|
|
CP0869497
|
5-(2-(2-Fluoroethoxy)ethoxy)-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C30H39FN4O8
|
1
|
| 1 |
Ki = 21.8 nM
|
|
|
|
CP0463698
|
N-[4-[methyl-[(10R)-2-oxo-3-propyl-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-10-yl]amino]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C27H33N5O2
|
1
|
| 1 |
Ki = 21.8 nM
|
|
|
|
CP0416052
|
4-[(2R)-2-[2-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H32N4O4S
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0411141
|
(11S)-N-[(4-cyanophenyl)methyl]-5-ethyl-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C24H19N3O3S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0472430
|
4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C28H32N4O2S2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0861003
|
1-(1-((4-Methoxy-1H-indol-3-yl)methyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one oxalate
Show/Hide
|
C24H26N4O6
|
1
|
| 1 |
Ki = 23.3 nM
|
|
|
|
CP0449146
|
1-(2-methoxyphenyl)-4-[4-(4-naphthalen-2-yltriazol-1-yl)butyl]piperazine
Show/Hide
|
C27H31N5O
|
1
|
| 1 |
Ki = 23.3 nM
|
|
|
|
CP0397121
|
1-[5-[1-(4-fluorophenyl)triazol-4-yl]pentyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C24H30FN5O
|
1
|
| 1 |
Ki = 23.7 nM
|
|
|
|
CP0415503
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[3-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]propoxy]ethoxy]ethoxy]propanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C81H120N18O19S
|
1
|
| 1 |
Ki = 23.78 nM
|
|
|
|
CP0467837
|
1-((1H-indol-3-yl)methyl)-4-(4-(methylthio)phenyl)piperidin-4-ol
Show/Hide
|
C21H24N2OS
|
1
|
| 1 |
Ki = 23.9 nM
|
|
|
|
CP0869493
|
5-(2-fluoroethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C28H35FN4O7
|
1
|
| 1 |
Ki = 23.9 nM
|
|
|
|
CP0426091
|
N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]quinoline-2-carboxamide
Show/Hide
|
C28H27N3O2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0481685
|
3,4-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C24H24F2N2O3S
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0396074
|
5-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azetidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H28N4O2S2
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0432718
|
2-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28FN3O3S
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0384351
|
7-[(2-(4-phenylpiperazin-1-yl)ethyl)(2-(thiophen-2-yl)ethyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C28H35N3OS
|
1
|
| 1 |
Ki = 24.6 nM
|
|
|
|
CP0040677
|
12-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0453913
|
5-chloro-N-[(3S)-1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C19H25ClN2O3S2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0453916
|
3-chloro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C21H27ClN2O3S
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0555953
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C98H154N18O28S
|
1
|
| 1 |
Ki = 25.27 nM
|
|
|
|
CP0891095
|
7-(4-(4-(2,4-Dimethoxyphenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C27H35N3O8
|
1
|
| 1 |
Ki = 25.3 nM
|
|
|
|
CP0371911
|
2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C23H26F3N3O
|
2
|
| 1 |
Ki = 26 nM
|
|
|
| 2 |
Ki = 387 nM
|
|
|
|
CP0452361
|
(R)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0376400
|
(-)-(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 26 nM
|
|
|
|
CP0375779
|
N-[4-[4-(2-methylsulfanylphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5OS
|
2
|
| 1 |
Ki = 26 nM
|
|
|
| 2 |
Ki = 37 nM
|
|
|
|
CP0540392
|
2-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C21H23Cl2N3O3S
|
1
|
| 1 |
Ki = 26 nM
|
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|
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CP0162167
|
2-Amino-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
Ki = 26.1 nM
|
|
|
|
CP0409196
|
1-((1H-indol-3-yl)methyl)-4-(2,3-dichlorophenyl)piperidin-4-ol
Show/Hide
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C20H20Cl2N2O
|
1
|
| 1 |
Ki = 26.1 nM
|
|
|
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CP0553679
|
(4S)-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[3-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]acetyl]amino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]pentanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
Show/Hide
|
C161H237N37O49S
|
1
|
| 1 |
Ki = 26.13 nM
|
|
|
|
CP0234732
|
1-(2-methoxyphenyl)-4-[5-[1-(4-methylsulfanylphenyl)triazol-4-yl]pentyl]piperazine
Show/Hide
|
C25H33N5OS
|
1
|
| 1 |
Ki = 26.6 nM
|
|
|
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CP0469370
|
1,1-dioxo-2-[6-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C24H28F3N3O3S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
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CP0384574
|
2-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C30H35N3O3
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0526778
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H32N4O2S2
|
1
|
| 1 |
Ki = 27 nM
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|
|
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CP0786650
|
4-(2-Fluoroethoxy)-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)-butyl)benzamide oxalic acid salt
Show/Hide
|
C26H34FN3O7
|
1
|
| 1 |
Ki = 27.1 nM
|
|
|
|
CP0381493
|
(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-1-[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S,3R)-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]-3-hydroxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C101H140N22O21S2
|
1
|
| 1 |
Ki = 27.32 nM
|
|
|
|
CP0557696
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C86H130N18O22S
|
1
|
| 1 |
Ki = 27.39 nM
|
|
|
|
CP0422348
|
7-({2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C25H33Cl2N3O
|
1
|
| 1 |
Ki = 27.4 nM
|
|
|
|
CP0904688
|
4-(4-Bromophenyl)-1-((4-(2-fluoroethoxy)-1H-indol-3-yl)-methyl)piperidin-4-ol oxalate
Show/Hide
|
C24H26BrFN2O6
|
1
|
| 1 |
Ki = 27.7 nM
|
|
|
|
CP0786649
|
4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
|
C29H34FN3O6S
|
1
|
| 1 |
Ki = 27.7 nM
|
|
|
|
CP0135680
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O2
|
1
|
| 1 |
Ki = 27.8 nM
|
|
|
|
CP0416728
|
2-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28ClN3O3S
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0558935
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[4-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]butanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C75H108N18O16S
|
1
|
| 1 |
Ki = 28.43 nM
|
|
|
|
CP0904376
|
(+/-)-3-Methyl-6-(naphthalen-2-yl)-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide
Show/Hide
|
C28H28BrNO2
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0466254
|
4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]azetidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H28N4O2S2
|
1
|
| 1 |
Ki = 29 nM
|
|
|
|
CP0449015
|
4-(4-chlorophenyl)-1-((1-methyl-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
Ki = 29.6 nM
|
|
|
|
CP0879779
|
endo-8-(Benzothien-3-ylmethyl)-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H21Cl2NOS
|
1
|
| 1 |
Ki = 29.8 nM
|
|
|
|
CP0135682
|
1-butyl-4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazine
Show/Hide
|
C17H27ClN2O
|
1
|
| 1 |
Ki = 29.8 nM
|
|
|
|
CP0448728
|
4-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H30Cl2N4O2S
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0483351
|
3-[6-[4-(2-ethoxyphenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C28H35N3O3S
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0499319
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C77H112N18O18S
|
1
|
| 1 |
Ki = 30.33 nM
|
|
|
|
CP0410743
|
1-(2-methoxyphenyl)-4-[4-(1-phenyltriazol-4-yl)butyl]piperazine
Show/Hide
|
C23H29N5O
|
2
|
| 1 |
Ki = 30.9 nM
|
|
|
| 2 |
Ki = 53.6 nM
|
|
|
|
CP0414548
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzenesulfonamide
Show/Hide
|
C23H30N4O2S2
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0478914
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]naphthalene-1-sulfonamide
Show/Hide
|
C27H32N4O2S2
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0400383
|
1-(2-methoxyphenyl)-4-[4-(1-naphthalen-2-yltriazol-4-yl)butyl]piperazine
Show/Hide
|
C27H31N5O
|
1
|
| 1 |
Ki = 31.5 nM
|
|
|
|
CP0860667
|
4-(2-(2-(2-Fluoroethoxy)ethoxy)ethoxy)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt
Show/Hide
|
C31H43F2N3O9
|
1
|
| 1 |
Ki = 31.7 nM
|
|
|
|
CP0350790
|
N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]pyridin-2-amine
Show/Hide
|
C20H28N4
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0525831
|
5-chloro-N-[[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]methyl]thiophene-2-sulfonamide
Show/Hide
|
C24H27ClN2O3S2
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0545014
|
2-[6-(4-naphthalen-1-ylpiperazin-1-yl)hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C26H31N5O
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0538566
|
2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexylsulfanyl]-1,3-benzoxazole
Show/Hide
|
C24H28N4OS2
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0772878
|
endo-8-(1H-Indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo-[3.2.1]octan-3-ol
Show/Hide
|
C22H23ClN2O
|
1
|
| 1 |
Ki = 33.4 nM
|
|
|
|
CP0059819
|
11-methyl-11-aza-tricyclo[12.4.0.0.3,8]octadeca-1(18),3(8),4,6,14,16-hexaen-6-ol
Show/Hide
|
C18H21NO
|
1
|
| 1 |
Ki = 33.5 nM
|
|
|
|
CP0071762
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H31N3O2
|
3
|
| 1 |
Ki = 33.6 nM
|
|
|
| 2 |
Ki = 52 nM
|
|
|
| 3 |
Ki = 186 nM
|
|
|
|
CP0906705
|
(E)-N-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)but-2-en-1-yl)-5-hydroxy-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C27H31FN4O7
|
1
|
| 1 |
Ki = 33.6 nM
|
|
|
|
CP0371912
|
2-(4-(4-phenyl-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C23H29N3O2
|
2
|
| 1 |
Ki = 34 nM
|
|
|
| 2 |
Ki = 319 nM
|
|
|
|
CP0487886
|
1-(2-methoxyphenyl)-4-(5-naphthalen-2-yloxypentyl)piperazine
Show/Hide
|
C26H32N2O2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0543362
|
1,1-dioxo-2-[5-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]pentyl]-1,2-benzothiazol-3-one
Show/Hide
|
C23H26F3N3O3S
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0494802
|
6-fluoro-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C25H29FN4O2
|
1
|
| 1 |
Ki = 34.1 nM
|
|
|
|
CP0181036
|
4-(dimethylamino)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide
Show/Hide
|
C24H34N4O2
|
1
|
| 1 |
Ki = 34.4 nM
|
|
|
|
CP0382715
|
7-[4-[(2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H30N4O3
|
1
|
| 1 |
Ki = 34.6 nM
|
|
|
|
CP0298954
|
1-Benzyl-4-(3-hydroxyphenyl)piperidine
Show/Hide
|
C18H21NO
|
2
|
| 1 |
Ki = 35 nM
|
|
|
| 2 |
Ki = 285 nM
|
|
|
|
CP0406918
|
N,1-dimethyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C24H30N4O3S
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0525902
|
(1S,2R,6S,7R)-4-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H34ClN3O2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0847307
|
4-(Dimethylamino)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C27H35FN4O6
|
1
|
| 1 |
Ki = 35.2 nM
|
|
|
|
CP0666613
|
endo-8-(1H-Indol-3-ylmethyl)-3-(3,4-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H22Cl2N2O
|
1
|
| 1 |
Ki = 35.3 nM
|
|
|
|
CP0400204
|
(4S)-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[3-[2-[2-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]acetyl]amino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]pentanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
Show/Hide
|
C165H245N37O51S
|
1
|
| 1 |
Ki = 35.77 nM
|
|
|
|
CP0513237
|
3-chloro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C19H23ClN2O3S2
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0382642
|
N-[[4-(methoxymethoxy)phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C31H39N3O3
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0417575
|
5-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H30Cl2N4O2S
|
1
|
| 1 |
Ki = 36 nM
|
|
|
|
CP0109326
|
5-Fluoro-1H-indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2FN4O
|
1
|
| 1 |
Ki = 36.8 nM
|
|
|
|
CP0403510
|
N-(cyclopropylmethyl)-4-fluoro-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C29H33FN2O3S
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0448727
|
4-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H31ClN4O2S
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0487624
|
4-[(2S)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0314424
|
1H-Indole-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C24H30N4O2
|
1
|
| 1 |
Ki = 37.4 nM
|
|
|
|
CP0059816
|
2,4-dichloro-3-hydroxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C18H19Cl2NO
|
1
|
| 1 |
Ki = 37.5 nM
|
|
|
|
CP0362283
|
1-(2-methoxyphenyl)-4-[4-[1-(4-methylsulfanylphenyl)triazol-4-yl]butyl]piperazine
Show/Hide
|
C24H31N5OS
|
1
|
| 1 |
Ki = 37.7 nM
|
|
|
|
CP0861000
|
1-(1-(Benzo[b]thiophen-3-ylmethyl)piperidin-4-yl)-1Hbenzo[d]imidazol-2-(3H)-one oxalate
Show/Hide
|
C23H23N3O5S
|
1
|
| 1 |
Ki = 37.8 nM
|
|
|
|
CP0847308
|
4-(2-Fluoroethoxy)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C27H33F2N3O7
|
1
|
| 1 |
Ki = 37.9 nM
|
|
|
|
CP0542761
|
2-N-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H30N8O
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0435436
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C26H31N3O2S
|
1
|
| 1 |
Ki = 38.6 nM
|
|
|
|
CP0445258
|
5-chloro-N-[(3R)-1-[2-(2-phenylphenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C22H23ClN2O3S2
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0432719
|
2-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28ClN3O3S
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0526779
|
6-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C26H32N4O2S
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0542763
|
4-N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C27H33Cl2N9
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0418174
|
(rac)-3-(3-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-o-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol
Show/Hide
|
C36H46N6O3
|
1
|
| 1 |
Ki = 39.1 nM
|
|
|
|
CP0504692
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-6-fluoroquinoline-3-carboxamide
Show/Hide
|
C24H25Cl2FN4O
|
1
|
| 1 |
Ki = 39.2 nM
|
|
|
|
CP0880729
|
endo-8-(5-Methoxy-1H-indol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C23H25ClN2O2
|
1
|
| 1 |
Ki = 39.4 nM
|
|
|
|
CP0059820
|
1-methoxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
Show/Hide
|
C19H23NO
|
1
|
| 1 |
Ki = 39.9 nM
|
|
|
|
CP0852046
|
endo-8-(Benzofur-3-ylmethyl)-3-(2,3-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H21Cl2NO2
|
1
|
| 1 |
Ki = 40.1 nM
|
|
|
|
CP0869500
|
(E)-N-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)but-2-en-1-yl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C27H31FN4O6
|
1
|
| 1 |
Ki = 40.4 nM
|
|
|
|
CP0439502
|
(+)-(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 40.6 nM
|
|
|
|
CP0453912
|
4-fluoro-N-[1-[2-(2-methylsulfanylphenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C19H23FN2O3S2
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0473055
|
(1R,2S,6R,7S)-4-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H37N3O3
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0880731
|
endo-8-(1H-Indol-3-ylmethyl)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H23FN2O
|
1
|
| 1 |
Ki = 41.4 nM
|
|
|
|
CP0375620
|
5-((4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)methyl)quinolin-8-ol
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
Ki = 41.4 nM
|
|
|
|
CP0391293
|
5-[(2S)-2-[2-[4-(1H-indol-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0362281
|
5-[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-1-yl]isoquinoline
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
Ki = 42.3 nM
|
|
|
|
CP0898479
|
5-(2-(2-(2-Fluoroethoxy)ethoxy)ethoxy)-N-(4-(4-(2-methoxy-phenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C32H43FN4O9
|
1
|
| 1 |
Ki = 42.4 nM
|
|
|
|
CP0433591
|
6-[1-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-4-yl]quinoline
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
Ki = 42.5 nM
|
|
|
|
CP0410495
|
(4S)-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]acetyl]amino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]pentanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
Show/Hide
|
C169H253N37O53S
|
1
|
| 1 |
Ki = 42.8 nM
|
|
|
|
CP0059097
|
N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C25H29ClN4O2
|
1
|
| 1 |
Ki = 43.1 nM
|
|
|
|
CP0396657
|
5-bromo-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]thiophene-2-carboxamide
Show/Hide
|
C21H28BrN3O2S
|
1
|
| 1 |
Ki = 43.7 nM
|
|
|
|
CP0389480
|
5-[1-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-4-yl]-1H-indole
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
Ki = 43.7 nM
|
|
|
|
CP0400278
|
1-(2-methoxyphenyl)-4-[3-[1-(4-methylsulfanylphenyl)triazol-4-yl]propyl]piperazine
Show/Hide
|
C23H29N5OS
|
1
|
| 1 |
Ki = 44.1 nM
|
|
|
|
CP0400205
|
(4S)-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]acetyl]amino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]pentanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
Show/Hide
|
C173H261N37O55S
|
1
|
| 1 |
Ki = 44.67 nM
|
|
|
|
CP0041389
|
Benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2N3O2
|
1
|
| 1 |
Ki = 44.8 nM
|
|
|
|
CP0420682
|
3-fluoro-N-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0482089
|
2-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H28ClN3O3S
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0482432
|
1-(2,3-dichlorophenyl)-4-methylpiperazine
Show/Hide
|
C11H14Cl2N2
|
1
|
| 1 |
Ki = 45.9 nM
|
|
|
|
CP0371883
|
3-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)quinazolin-4(3H)-one
Show/Hide
|
C22H26N4O
|
2
|
| 1 |
Ki = 46 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0484860
|
4-fluoro-N-[[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C26H29FN2O3S
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0375463
|
N,1-dimethyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]pyrazole-4-sulfonamide
Show/Hide
|
C21H32N4O3S
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0569637
|
2-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H28N8O
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0400385
|
5-[4-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-1-yl]-1H-indole
Show/Hide
|
C24H26Cl2N6
|
1
|
| 1 |
Ki = 46.6 nM
|
|
|
|
CP0397122
|
1-[4-[1-(4-fluorophenyl)triazol-4-yl]butyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C23H28FN5O
|
1
|
| 1 |
Ki = 46.7 nM
|
|
|
|
CP0927947
|
1-(Benzo[b]thiophen-2-ylmethyl)-4-(4-bromophenyl)-piperidin-4-ol oxalate
Show/Hide
|
C22H23NO5S
|
1
|
| 1 |
Ki = 46.8 nM
|
|
|
|
CP0156136
|
N-[4-[4-(2-chloro-5-methylphenyl)piperazin-1-yl]butyl]-2-oxo-3H-1,3-benzoxazole-5-carboxamide
Show/Hide
|
C23H27ClN4O3
|
1
|
| 1 |
Ki = 46.9 nM
|
|
|
|
CP0469532
|
(S)-(4-(2-((5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)(1H-indol-2-yl)methanone
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
Ki = 47.5 nM
|
|
|
|
CP0311502
|
1,1-dioxo-2-[6-(4-phenylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C23H29N3O3S
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0381348
|
3-chloro-N-[[1-[2-(2-methylsulfanylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C21H27ClN2O3S2
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0413769
|
4-fluoro-N-[[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0375465
|
4-fluoro-N-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C23H31FN2O3S
|
1
|
| 1 |
Ki = 50 nM
|
|
|
|
CP0410746
|
1-[4-[4-(9H-fluoren-2-yl)triazol-1-yl]butyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C30H33N5O
|
1
|
| 1 |
Ki = 50.1 nM
|
|
|
|
CP0486999
|
4-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C22H29FN2O3S
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0683568
|
2-fluoro-N-(1-(2-(2-isopropylphenoxy)ethyl)piperidin-4-yl)benzenesulfonamide
Show/Hide
|
C22H29FN2O3S
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0391600
|
1,1-dioxo-2-[6-(4-pyrimidin-2-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C21H27N5O3S
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0444621
|
5-[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-1-yl]-1H-indole
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
Ki = 51.8 nM
|
|
|
|
CP0771814
|
4-(2-(2-(2-Fluoroethoxy)ethoxy)ethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-l)butyl)benzamide oxalic acid salt
Show/Hide
|
C30H42FN3O9
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0375466
|
N-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H30N2O3S
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0232302
|
N-[4-[4-(2-oxo-1,3-dihydroindol-4-yl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0542766
|
2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[4-(4-phenylpiperazin-1-yl)butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C27H35N9
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0434239
|
(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C104H160N24O28S
|
1
|
| 1 |
Ki = 52.03 nM
|
|
|
|
CP0494803
|
N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H29ClN4O2
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0382643
|
N-[(1S)-1-phenylethyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0909483
|
6-(1-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)quinoline
Show/Hide
|
C25H26Cl2N6
|
1
|
| 1 |
Ki = 53.9 nM
|
|
|
|
CP0377728
|
(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C90H138N18O24S
|
1
|
| 1 |
Ki = 53.92 nM
|
|
|
|
CP0372385
|
1-(benzofuran-3-ylmethyl)-4-(4-(methylthio)phenyl)piperidin-4-ol
Show/Hide
|
C21H23NO2S
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0375468
|
4-fluoro-N-methyl-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C26H29FN2O3S
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0231075
|
4-(2-fluoroethyl)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzamide
Show/Hide
|
C24H32FN3O2
|
1
|
| 1 |
Ki = 54.5 nM
|
|
|
|
CP0381742
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]-9H-fluorene-3-carboxamide
Show/Hide
|
C28H29Cl2N3O2
|
1
|
| 1 |
Ki = 54.7 nM
|
|
|
|
CP0463700
|
(10R)-3-[6-(4-phenylbutoxy)hexyl]-10-(propylamino)-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C29H41N3O2
|
1
|
| 1 |
Ki = 54.8 nM
|
|
|
|
CP0356698
|
N-[4-[4-[3-(methanesulfonamido)phenyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H32N4O3S
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0530033
|
(1R,2S,6R,7S)-4-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H33Cl2N3O2
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0400351
|
7-Methyl-6,7,8,9,10,15-hexahydroindolo[2,3-f][3]benzazecine
Show/Hide
|
C20H22N2
|
1
|
| 1 |
Ki = 55.1 nM
|
|
|
|
CP0847579
|
4-(2-Fluoroethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-transbutyl-2-enyl)benzamide oxalic acid salt
Show/Hide
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C26H32FN3O7
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1
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| 1 |
Ki = 55.3 nM
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CP0474888
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11-Butyryloxy-N-n-propylnoraporphine
Show/Hide
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C23H27NO2
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2
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| 1 |
Ki = 55.5 nM
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| 2 |
Ki > 10000 nM
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CP0414547
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1-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
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C28H30N4OS
|
1
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| 1 |
Ki = 56 nM
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CP0443217
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5-[1-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]triazol-4-yl]-1H-indole
Show/Hide
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C24H26Cl2N6
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1
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| 1 |
Ki = 56.1 nM
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CP0477829
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N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-5-methylthiophene-2-carboxamide
Show/Hide
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C22H31N3O2S
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1
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| 1 |
Ki = 56.5 nM
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CP0410742
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1-[4-[1-(9H-fluoren-2-yl)triazol-4-yl]butyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
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C30H33N5O
|
1
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| 1 |
Ki = 57.2 nM
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CP0847769
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5-Bromo-2-(2-fluoroethoxy)-3-methoxy-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
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C27H33BrFN3O8
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1
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| 1 |
Ki = 57.6 nM
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CP0402682
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(-)-(S)-N6-Propyl-N6-(2-(4-(quinolin-5-yl)piperazin-1-yl)ethyl)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
Show/Hide
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C25H34N6S
|
1
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| 1 |
Ki = 57.7 nM
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CP0416669
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1-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
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C27H31Cl2N3O
|
1
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| 1 |
Ki = 58 nM
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CP0224532
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1-(2-chloro-3-ethylphenyl)-4-methylpiperazine
Show/Hide
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C13H19ClN2
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1
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| 1 |
Ki = 58.1 nM
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CP0409198
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ethyl 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidine-4-carboxylate
Show/Hide
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C23H25ClN2O2
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1
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| 1 |
Ki = 58.8 nM
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CP0103545
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(-)-5-hydroxy-2-(dipropylamino)tetralin
Show/Hide
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C16H25NO
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1
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| 1 |
Ki = 58.8 nM
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CP0116811
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5-Bromo-N-{4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-2,3-dimethoxy-benzamide
Show/Hide
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C23H28BrCl2N3O3
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1
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| 1 |
Ki = 58.8 nM
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CP0532785
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2-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H30N4O2S
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1
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| 1 |
Ki = 59 nM
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CP0905141
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4-(2-(2-Fluoroethoxy)ethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-trans-butyl-2-enyl)benzamide oxalic acid salt
Show/Hide
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C28H36FN3O8
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1
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| 1 |
Ki = 59.2 nM
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CP0467821
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methyl 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidine-4-carboxylate
Show/Hide
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C22H23ClN2O2
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1
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| 1 |
Ki = 60 nM
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CP0371906
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2-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
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C22H27N3O
|
2
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| 1 |
Ki = 60 nM
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| 2 |
Ki = 189 nM
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CP0486997
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2,5-difluoro-N-[1-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
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C22H26F2N2O3S
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1
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| 1 |
Ki = 60 nM
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CP0906704
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(E)-5-(2-fluoroethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but-2-en-1-yl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
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C28H33FN4O7
|
1
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| 1 |
Ki = 60 nM
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CP0385629
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N-methyl-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
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C23H32N2O3S
|
1
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| 1 |
Ki = 60 nM
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CP0402811
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4-fluoro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
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C24H31FN2O3S
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1
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| 1 |
Ki = 60 nM
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CP0569767
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2-[6-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C24H31N5O3
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1
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| 1 |
Ki = 60 nM
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CP0463699
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(10R)-10-(methylamino)-3-[6-(4-phenylbutoxy)hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
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C27H37N3O2
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1
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| 1 |
Ki = 60.6 nM
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CP0861002
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1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-iodophenyl)piperidin-4-ol oxalate
Show/Hide
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C21H22IN3O5
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1
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| 1 |
Ki = 61 nM
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CP0772206
|
SID56463240
Show/Hide
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C26H32ClN3O2
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1
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| 1 |
Ki = 61 nM
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CP0387086
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1-[4-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
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C30H33FN4O3
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1
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| 1 |
Ki = 62 nM
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CP0568317
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2-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C23H28F3N5O
|
1
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| 1 |
Ki = 62 nM
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CP0474295
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4-[4-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]triazol-1-yl]-N,N-dimethylaniline
Show/Hide
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C26H36N6O
|
1
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| 1 |
Ki = 62.6 nM
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CP0490608
|
1-(2-methoxyphenyl)-4-[5-[1-(2-methoxyphenyl)triazol-4-yl]pentyl]piperazine
Show/Hide
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C25H33N5O2
|
1
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| 1 |
Ki = 62.7 nM
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CP0286302
|
7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-2-ol
Show/Hide
|
C19H23NO
|
1
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| 1 |
Ki = 63 nM
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CP0381352
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3,4-difluoro-N-[1-[2-(2-phenylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
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C25H26F2N2O3S
|
1
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| 1 |
Ki = 63 nM
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CP0554781
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
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C25H27Cl2N3OS
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1
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| 1 |
Ki = 63.1 nM
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CP0449717
|
2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethanol
Show/Hide
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C12H16Cl2N2O
|
1
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| 1 |
Ki = 63.7 nM
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CP0555051
|
1-(2-methoxyphenyl)-4-[3-(1-phenyltriazol-4-yl)propyl]piperazine
Show/Hide
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C22H27N5O
|
1
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| 1 |
Ki = 64 nM
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CP0376749
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N-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
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C36H48N4O3
|
1
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| 1 |
Ki = 64 nM
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CP0554334
|
(4S)-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-4-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[6-[3-[3-[3,4-dimethoxy-5-[[(2S)-1-prop-2-enylpyrrolidin-2-yl]methylcarbamoyl]phenyl]propylsulfanyl]-2,5-dioxopyrrolidin-1-yl]hexanoylamino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]pentanoyl]amino]acetyl]amino]-6-[[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetyl]amino]hexanoyl]amino]pentanoyl]amino]-4-oxobutanoyl]amino]-4-oxobutanoyl]amino]-3-phenylpropanoyl]amino]-6-[4-[(1E,3E)-4-[4-(dimethylamino)phenyl]buta-1,3-dienyl]-2,6-dimethylpyridin-1-ium-1-yl]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-carboxybutanoyl]amino]-5-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-5-oxopentanoic acid
Show/Hide
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C169H236N37O44S+
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1
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| 1 |
Ki = 64.16 nM
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CP0478203
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-benzothiophene-3-carboxamide
Show/Hide
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C23H25Cl2N3OS
|
1
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| 1 |
Ki = 64.7 nM
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CP0856728
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4-(2-(2-Fluoroethoxy)ethoxy)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)-trans-but-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C29H37F2N3O8
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1
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| 1 |
Ki = 64.8 nM
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CP0873320
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7-methyl-2,3-dihydroxy-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine hydrobromide
Show/Hide
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C18H22BrNO2
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2
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| 1 |
Ki = 65.7 nM
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| 2 |
Ki > 5000 nM
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CP0486994
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3-chloro-N-[[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C23H31ClN2O3S
|
1
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| 1 |
Ki = 66 nM
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CP0869499
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(E)-N-(4-(4-(2-(2-Fluoroethoxy)phenyl)piperazin-1-yl)but-2-en-1-yl)-5-methoxy-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C28H33FN4O7
|
1
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| 1 |
Ki = 66.3 nM
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CP0407878
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-2-carboxamide
Show/Hide
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C25H30N4O2
|
1
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| 1 |
Ki = 66.8 nM
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CP0381395
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5-chloro-N-[1-[2-(2,3-dichlorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H17Cl3N2O3S2
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1
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| 1 |
Ki = 67 nM
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CP0495774
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3-((4-(4-chlorophenyl)-4-methoxypiperidin-1-yl)methyl)-1H-indole
Show/Hide
|
C21H23ClN2O
|
1
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| 1 |
Ki = 68.1 nM
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CP0139957
|
3-[Bis-(4-fluoro-phenyl)-methoxy]-8-butyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C24H29F2NO
|
1
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| 1 |
Ki = 68.1 nM
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CP0528747
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6-fluoro-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-2-carboxamide
Show/Hide
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C25H29FN4O2
|
1
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| 1 |
Ki = 68.2 nM
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CP0394596
|
(+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-ynylamino}-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C27H35N3O
|
1
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| 1 |
Ki = 68.4 nM
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CP0510175
|
US8748608, 23
Show/Hide
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C29H33N3O3
|
1
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| 1 |
Ki = 68.4 nM
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CP0181449
|
1-(3-Hydroxyphenyl)-4-propylpiperazine
Show/Hide
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C13H20N2O
|
2
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| 1 |
Ki = 69 nM
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| 2 |
Ki = 721 nM
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CP0452963
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1-(2-methoxyphenyl)-4-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]piperazine
Show/Hide
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C29H33N5O
|
1
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| 1 |
Ki = 69 nM
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CP0375617
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N-(1-benzothiophen-3-ylmethyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-propylbutan-1-amine
Show/Hide
|
C27H37N3OS
|
1
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| 1 |
Ki = 69.9 nM
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CP0384350
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6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalene-2,3-diol
Show/Hide
|
C25H35N3O2
|
1
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| 1 |
Ki = 70.3 nM
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CP0844267
|
4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)-trans-but-2-enyl)benzamides oxalic acid salt
Show/Hide
|
C29H32FN3O6S
|
1
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| 1 |
Ki = 70.5 nM
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CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
3
|
| 1 |
Ki = 71 nM
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| 2 |
Ki = 72 nM
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| 3 |
Ki = 150 nM
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CP0912198
|
8-(Benzo[b]thiophen-3-ylmethyl)-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate
Show/Hide
|
C25H27N3O5S
|
1
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| 1 |
Ki = 71.4 nM
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CP0445256
|
4-fluoro-N-[1-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C22H27FN2O3S
|
1
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| 1 |
Ki = 72 nM
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CP0453914
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N-[1-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
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C20H26N2O3S2
|
1
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| 1 |
Ki = 72 nM
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CP0400253
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-3-[(dimethylamino)methyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C28H39F3N8O
|
3
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| 1 |
Ki = 72 nM
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| 2 |
Ki = 191 nM
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| 3 |
Ki = 301 nM
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CP0376253
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N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C24H28ClN3O3
|
1
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| 1 |
Ki = 72.3 nM
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CP0463017
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3-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-quinazolin-4(3H)-one
Show/Hide
|
C23H25F3N4O
|
2
|
| 1 |
Ki = 73 nM
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| 2 |
Ki > 10000 nM
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CP0375407
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1-[3-[1-(4-fluorophenyl)triazol-4-yl]propyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C22H26FN5O
|
1
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| 1 |
Ki = 73.5 nM
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CP0207464
|
7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-3-ol
Show/Hide
|
C19H23NO
|
1
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| 1 |
Ki = 74 nM
|
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CP0530888
|
N-[[4-[(dimethylamino)methyl]phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C32H42N4O
|
1
|
| 1 |
Ki = 75 nM
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CP0478414
|
1-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31Cl2N3O
|
1
|
| 1 |
Ki = 75 nM
|
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CP0063621
|
N-[(3R)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
1
|
| 1 |
Ki = 75.8 nM
|
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CP0433626
|
2-ethoxy-N-[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]benzamide
Show/Hide
|
C22H27FN2O3
|
1
|
| 1 |
Ki = 76 nM
|
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CP0472682
|
5-[4-[2-[4-(3-chlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31ClN4O2S
|
1
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| 1 |
Ki = 76 nM
|
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CP0426092
|
5-chloro-N-[1-[2-(2,5-dichlorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H17Cl3N2O3S2
|
1
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| 1 |
Ki = 78 nM
|
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CP0385310
|
US10913711, Compound 10j
Show/Hide
|
C28H32F2N2O2S
|
1
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| 1 |
Ki = 78.6 nM
|
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CP0508202
|
N-[1-[2-(2-propan-2-ylphenoxy)ethyl]pyrrolidin-3-yl]quinoline-2-carboxamide
Show/Hide
|
C25H29N3O2
|
1
|
| 1 |
Ki = 79 nM
|
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CP0375302
|
5-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-1-yl]isoquinoline
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
Ki = 79.3 nM
|
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CP0463676
|
N-[(3R)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H30ClFN4O
|
1
|
| 1 |
Ki = 80.2 nM
|
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CP0384679
|
N-(3-methylphenyl)-3-(4-pyridin-2-ylpiperidin-1-yl)propanamide
Show/Hide
|
C20H25N3O
|
2
|
| 1 |
Ki = 80.3 nM
|
|
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| 2 |
Ki = 5940 nM
|
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CP0389180
|
1-(2,3-dichlorophenyl)-4-[4-(1-naphthalen-2-yltriazol-4-yl)butyl]piperazine
Show/Hide
|
C26H27Cl2N5
|
1
|
| 1 |
Ki = 80.8 nM
|
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CP0571682
|
2-[4-[3-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
Ki = 81 nM
|
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CP0384573
|
1-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
|
C30H32N4O
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0574555
|
[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]-pyridin-2-ylmethanone
Show/Hide
|
C23H29Cl2N5O
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0419602
|
7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine
Show/Hide
|
C21H24N2
|
2
|
| 1 |
Ki = 82.6 nM
|
|
|
| 2 |
Ki = 253 nM
|
|
|
|
CP0409195
|
N-[4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-yl]acetamide
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
Ki = 83.1 nM
|
|
|
|
CP0410750
|
6-[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-1-yl]isoquinoline
Show/Hide
|
C26H30N6O
|
1
|
| 1 |
Ki = 83.4 nM
|
|
|
|
CP0384905
|
US8748608, 22
Show/Hide
|
C28H29Cl2N3O2
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0381350
|
N-[1-(2-phenoxyethyl)piperidin-4-yl]thiophene-2-sulfonamide
Show/Hide
|
C17H22N2O3S2
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0500313
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]propanamide
Show/Hide
|
C18H29N3O2
|
1
|
| 1 |
Ki = 84 nM
|
|
|
|
CP0849204
|
3-Chloro-N-{1-[2-(biphenyl-2-yloxy)ethyl]piperidin-4-yl}-benzenesulfonamide
Show/Hide
|
C25H27ClN2O3S
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0545007
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-2-thione
Show/Hide
|
C26H33ClN4S
|
1
|
| 1 |
Ki = 85 nM
|
|
|
|
CP0431322
|
(12S)-11,12-dimethyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene
Show/Hide
|
C21H24N2
|
1
|
| 1 |
Ki = 85.3 nM
|
|
|
|
CP0430951
|
5-((4-(2-((7-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)methyl)quinolin-8-ol
Show/Hide
|
C28H36N4O2
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0202373
|
3-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0519609
|
5-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C17H15ClN4O2S
|
1
|
| 1 |
Ki = 87 nM
|
|
|
|
CP0444479
|
N-[2-[(1R,2S)-2-[[(2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]methyl]cyclopropyl]ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31N5O2
|
2
|
| 1 |
Ki = 87.8 nM
|
|
|
| 2 |
Ki = 1610 nM
|
|
|
|
CP0377980
|
(+/-)-11-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-N-propylnoraporphine
Show/Hide
|
C34H43N3O2
|
1
|
| 1 |
Ki = 88 nM
|
|
|
|
CP0456795
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-9-oxofluorene-2-carboxamide
Show/Hide
|
C28H27Cl2N3O2
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0530680
|
(11S)-5-ethyl-N-[(4-fluorophenyl)methyl]-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C23H19FN2O3S
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0384693
|
3-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31ClFN3O2S
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0417214
|
8-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]-6,7,8,9-tetrahydro-1H-benzo[e]indol-2(3H)-one
Show/Hide
|
C27H36N4O
|
1
|
| 1 |
Ki = 90.6 nM
|
|
|
|
CP0397826
|
(13aS)-3,9,10-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0074631
|
6-methyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]benzazecine
Show/Hide
|
C16H19NS
|
2
|
| 1 |
Ki = 92 nM
|
|
|
| 2 |
Ki = 198 nM
|
|
|
|
CP0543385
|
1,1-dioxo-2-[5-(4-pyridin-2-ylpiperazin-1-yl)pentyl]-1,2-benzothiazol-3-one
Show/Hide
|
C21H26N4O3S
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0435434
|
N-[4-[4-(2-cyanophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C26H28N4OS
|
1
|
| 1 |
Ki = 92.9 nM
|
|
|
|
CP0417546
|
(2S)-1-[4-(2,3-dichlorophenyl)piperazin-1-yl]butan-2-ol
Show/Hide
|
C14H20Cl2N2O
|
1
|
| 1 |
Ki = 93.1 nM
|
|
|
|
CP0407076
|
3-chloro-N-[8-[2-(3-phenylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C27H29ClN2O3S
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0417077
|
1-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H30Cl3N3O
|
1
|
| 1 |
Ki = 94 nM
|
|
|
|
CP0093139
|
1-(2-methoxyphenyl)-4-[4-[1-(4-thiophen-3-ylphenyl)triazol-4-yl]butyl]piperazine
Show/Hide
|
C27H31N5OS
|
1
|
| 1 |
Ki = 94.3 nM
|
|
|
|
CP0356696
|
N-[4-[4-(1H-indol-4-yl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0440174
|
4-fluoro-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C23H30FN3O2
|
1
|
| 1 |
Ki = 95.2 nM
|
|
|
|
CP0867161
|
1-[3-(2,4-Dimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride
Show/Hide
|
C22H31ClN2O2
|
1
|
| 1 |
Ki = 97 nM
|
|
|
|
CP0449016
|
4-biphenyl-4-yl-1-(1H-indol-3-ylmethyl)-piperidin-4-ol
Show/Hide
|
C26H26N2O
|
1
|
| 1 |
Ki = 98.4 nM
|
|
|
|
CP0519086
|
4-thiophen-3-yl-N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
|
C26H28F3N3OS
|
1
|
| 1 |
Ki = 99.7 nM
|
|
|
|
CP0397771
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-9-oxofluorene-4-carboxamide
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0382131
|
(11S)-5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H18N2O3S2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0396653
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-4-methylsulfanylbenzamide
Show/Hide
|
C24H33N3O2S
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0891097
|
7-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C26H33N3O7
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0107214
|
3-fluoro-N-[1-[2-(2-propan-2-ylphenoxy)ethyl]piperidin-4-yl]benzenesulfonamide
Show/Hide
|
C22H29FN2O3S
|
1
|
| 1 |
Ki = 102 nM
|
|
|
|
CP0042204
|
1H-Indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H26Cl2N4O
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0547198
|
1-(2,3-dichlorophenyl)-4-[4-(4-naphthalen-2-yltriazol-1-yl)butyl]piperazine
Show/Hide
|
C26H27Cl2N5
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0485627
|
4-[1-(2,5-dichlorophenoxy)pentyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C19H26Cl2N6O
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0850796
|
5-N-(1-{2-[(Propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-quinolinesulfonamide
Show/Hide
|
C25H31N3O3S
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0871615
|
N-((1S,4r)-4-(2-((2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholino)ethyl)cyclohexyl)-1H-indole-2-carboxamide
Show/Hide
|
C27H35N5O2
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0389448
|
N-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-2-[2-(methoxymethoxy)phenoxy]ethanamine
Show/Hide
|
C27H31NO5
|
1
|
| 1 |
Ki = 104.71 nM
|
|
|
|
CP0258622
|
(13aR)-3,9,10-trimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-2-ol
Show/Hide
|
C20H23NO4
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0471830
|
2-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H27Cl2N3O3S
|
1
|
| 1 |
Ki = 105 nM
|
|
|
|
CP0501761
|
1-((1H-indol-3-yl)methyl)-4-(3-(trifluoromethyl)phenyl)piperidin-4-ol
Show/Hide
|
C21H21F3N2O
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0382710
|
N-[2-[2-[[(2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]methyl]cyclopropyl]ethyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31N5O2
|
2
|
| 1 |
Ki = 106 nM
|
|
|
| 2 |
Ki = 8280 nM
|
|
|
|
CP0532783
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-4-methyl-N-phenylbenzenesulfonamide
Show/Hide
|
C30H36N4O2S2
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0380992
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-5-phenylthiophene-2-carboxamide
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0375440
|
4-(2-fluoroethyl)-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C25H34FN3O2
|
1
|
| 1 |
Ki = 108 nM
|
|
|
|
CP0402681
|
(-)-(S)-N6-Propyl-N6-(2-(4-(quinolin-4-yl)piperazin-1-yl)ethyl)-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine
Show/Hide
|
C25H34N6S
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0093141
|
1-(2-methoxyphenyl)-4-[5-[1-(4-thiophen-3-ylphenyl)triazol-4-yl]pentyl]piperazine
Show/Hide
|
C28H33N5OS
|
1
|
| 1 |
Ki = 109 nM
|
|
|
|
CP0569929
|
2-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C24H32N6O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0397169
|
4-chloro-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C23H30ClN3O2
|
1
|
| 1 |
Ki = 111 nM
|
|
|
|
CP0421822
|
1-[(6,6-diphenyl-1,4-dioxan-2-yl)methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H32N2O3
|
1
|
| 1 |
Ki = 112.2 nM
|
|
|
|
CP0371905
|
2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1, 2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
|
C22H24F3N3O3S
|
2
|
| 1 |
Ki = 113 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0105348
|
(S)-2,9-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline-3,10-diol
Show/Hide
|
C19H21NO4
|
1
|
| 1 |
Ki = 113 nM
|
|
|
|
CP0459145
|
2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C24H31N3O4S
|
1
|
| 1 |
Ki = 113 nM
|
|
|
|
CP0382713
|
7-[4-[(5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H30N4O3
|
1
|
| 1 |
Ki = 113 nM
|
|
|
|
CP0402972
|
(+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C27H39N3O
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0050995
|
(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol
Show/Hide
|
C19H21NO
|
2
|
| 1 |
Ki = 114 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0401190
|
(10R)-10-amino-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C10H11N3O
|
2
|
| 1 |
Ki = 114 nM
|
|
|
| 2 |
Ki = 12100 nM
|
|
|
|
CP0417069
|
1-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
|
C28H33N3O2
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0470625
|
(rac)-3-(3-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol
Show/Hide
|
C36H46N6O3
|
1
|
| 1 |
Ki = 115 nM
|
|
|
|
CP0376752
|
N-[(1R)-1-phenylethyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 116 nM
|
|
|
|
CP0417065
|
3-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C25H30N4O2S
|
1
|
| 1 |
Ki = 118 nM
|
|
|
|
CP0460211
|
4-(4-(2-Methoxyphenyl)piperazin-1-yl)-N-(naphthalen-2-ylmethyl)-N-propylbutan-1-amine
Show/Hide
|
C29H39N3O
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0181209
|
(-)-Tetrahydroberberine
Show/Hide
|
C20H21NO4
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0381617
|
4-(dimethylamino)-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C25H36N4O2
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0381618
|
6-chloro-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C22H29ClN4O2
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0869494
|
(E)-5-Methoxy-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but-2-en-1-yl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C27H32N4O7
|
1
|
| 1 |
Ki = 119 nM
|
|
|
|
CP0445424
|
3-((4-(4-chlorophenyl)-4-fluoropiperidin-1-yl)methyl)-1H-indole
Show/Hide
|
C20H20ClFN2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0045034
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]pyrazolo[1,5-a]pyridine-2-carboxamide
Show/Hide
|
C23H29N5O2
|
2
|
| 1 |
Ki = 120 nM
|
|
|
| 2 |
Ki = 150 nM
|
|
|
|
CP0860158
|
(E)-5-(2-(2-Fluoroethoxy)ethoxy)-N-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)but-2-en-1-yl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C30H37FN4O8
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0569537
|
[4-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propyl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C24H30Cl2N4O
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0455784
|
(10R)-10-(methylamino)-3-[4-(4-phenylbutoxy)butyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0417576
|
5-[4-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H30Cl2N4O2S
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0416668
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0472714
|
(10R)-10-(methylamino)-3-[12-(4-phenylbutoxy)dodecyl]-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-2-one
Show/Hide
|
C33H49N3O2
|
1
|
| 1 |
Ki = 124 nM
|
|
|
|
CP0375438
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C25H31N3O3
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0381642
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C25H31N3O2S
|
1
|
| 1 |
Ki = 125 nM
|
|
|
|
CP0449026
|
1-((1H-indol-3-yl)methyl)-4-(4-fluorophenyl)piperidin-4-ol
Show/Hide
|
C20H21FN2O
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0397957
|
3-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C25H31FN4O4
|
1
|
| 1 |
Ki = 127 nM
|
|
|
|
CP0384369
|
2-(4-phenylpiperidin-1-yl)-N-(m-tolyl)acetamide
Show/Hide
|
C20H24N2O
|
2
|
| 1 |
Ki = 127 nM
|
|
|
| 2 |
Ki = 821 nM
|
|
|
|
CP0426892
|
2-[4-[4-(N-benzylanilino)piperidin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0397773
|
4-ethenyl-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0469462
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C27H33N3O2S
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0435244
|
1-((1H-indol-3-yl)methyl)-4-(3-chlorophenyl)piperidin-4-ol
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
Ki = 129 nM
|
|
|
|
CP0568817
|
2-[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C23H30N6O
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0576950
|
[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperazin-1-yl]-(1-methylindazol-3-yl)methanone
Show/Hide
|
C25H30Cl2N6O
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0903635
|
4-(2-Fluoroethyl)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)-transbutyl-2-enyl)benzamide oxalic acid salt
Show/Hide
|
C26H32FN3O6
|
1
|
| 1 |
Ki = 131 nM
|
|
|
|
CP0534532
|
N-[4-[4-(2-oxo-1,3-dihydrobenzimidazol-4-yl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C26H29N5O2
|
1
|
| 1 |
Ki = 131 nM
|
|
|
|
CP0416732
|
2-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C23H27Cl2N3O3S
|
1
|
| 1 |
Ki = 132 nM
|
|
|
|
CP0157764
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
2
|
| 1 |
Ki = 132 nM
|
|
|
| 2 |
Ki = 151 nM
|
|
|
|
CP0167372
|
US8748608, 20
Show/Hide
|
C28H30Cl2N4O3
|
1
|
| 1 |
Ki = 134 nM
|
|
|
|
CP0382695
|
N-[4-[(2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C23H29N5O2
|
2
|
| 1 |
Ki = 134 nM
|
|
|
| 2 |
Ki = 21000 nM
|
|
|
|
CP0510649
|
N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]naphthalene-2-carboxamide
Show/Hide
|
C33H37N3O
|
1
|
| 1 |
Ki = 136 nM
|
|
|
|
CP0377049
|
N-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C35H46N4O3
|
1
|
| 1 |
Ki = 136 nM
|
|
|
|
CP0266687
|
1-(2-methoxyphenyl)-4-[4-(4-phenyltriazol-1-yl)butyl]piperazine
Show/Hide
|
C23H29N5O
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0224533
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C26H32ClN3O3
|
1
|
| 1 |
Ki = 137 nM
|
|
|
|
CP0364794
|
1-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C10H12Cl2N2
|
1
|
| 1 |
Ki = 137.3 nM
|
|
|
|
CP0397772
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H32N4O2
|
1
|
| 1 |
Ki = 138 nM
|
|
|
|
CP0375299
|
1-(2-methoxyphenyl)-4-[4-[1-(2-methoxyphenyl)triazol-4-yl]butyl]piperazine
Show/Hide
|
C24H31N5O2
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0157763
|
1-(2-chloro-3-ethylphenyl)piperazine
Show/Hide
|
C12H17ClN2
|
1
|
| 1 |
Ki = 139 nM
|
|
|
|
CP0371910
|
3-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)quinazolin-4(3H)-one
Show/Hide
|
C22H25ClN4O
|
2
|
| 1 |
Ki = 140 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0853601
|
1-Methyl-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-1H-pyrazole-4-sulfonamide
Show/Hide
|
C20H30N4O3S
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0466448
|
N-[4-[4-(3-hydroxyphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0454412
|
(+)-R-11-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-N-propylnoraporphine
Show/Hide
|
C34H43N3O2
|
1
|
| 1 |
Ki = 141 nM
|
|
|
|
CP0448726
|
5-[4-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31ClN4O2S
|
1
|
| 1 |
Ki = 141 nM
|
|
|
|
CP0495705
|
2-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C28H30N4O4
|
1
|
| 1 |
Ki = 141 nM
|
|
|
|
CP0378423
|
7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C25H35N3O
|
2
|
| 1 |
Ki = 142 nM
|
|
|
| 2 |
Ki = 213 nM
|
|
|
|
CP0495707
|
3-[6-[4-(2-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H31Cl2N3O2S
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0568316
|
2-[6-(4-quinolin-8-ylpiperazin-1-yl)hexyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0887641
|
7-(4-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-piperidin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C27H32N4O7
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0465278
|
6-bromo-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C22H29BrN4O2
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0448742
|
4-[4-[2-[4-(3,4-dichlorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H30Cl2N4O2S
|
1
|
| 1 |
Ki = 145 nM
|
|
|
|
CP0860096
|
2,5-Difluoro-N-(1-{2-[(propan-2-yl)phenoxy]ethyl}piperidin-4-yl)-benzenesulfonamide
Show/Hide
|
C22H28F2N2O3S
|
1
|
| 1 |
Ki = 147 nM
|
|
|
|
CP0379465
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H32F3N7O
|
3
|
| 1 |
Ki = 148 nM
|
|
|
| 2 |
Ki = 511 nM
|
|
|
| 3 |
Ki = 702 nM
|
|
|
|
CP0475051
|
4-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H31F3N4O2S
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0545010
|
2-[[4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H24ClN5O
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0475050
|
5-[4-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C27H31F3N4O2S
|
1
|
| 1 |
Ki = 149 nM
|
|
|
|
CP0480200
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-5-methyl-1H-imidazole-2-carboxamide
Show/Hide
|
C21H30ClN5O2
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0375439
|
4-(2-hydroxyethyl)-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C25H35N3O3
|
1
|
| 1 |
Ki = 151 nM
|
|
|
|
CP0396656
|
2,3-dimethoxy-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]benzamide
Show/Hide
|
C25H35N3O4
|
1
|
| 1 |
Ki = 152 nM
|
|
|
|
CP0424212
|
1-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-indolin-2-one
Show/Hide
|
C22H27N3O
|
2
|
| 1 |
Ki = 153 nM
|
|
|
| 2 |
Ki = 162 nM
|
|
|
|
CP0853986
|
3-{2-Hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-2-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H32N4O4
|
1
|
| 1 |
Ki = 153 nM
|
|
|
|
CP0869496
|
(E)-5-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)-N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)but-2-en-1-yl)-1H-indole-2-carboxamide oxalic acid
Show/Hide
|
C32H41FN4O9
|
1
|
| 1 |
Ki = 155 nM
|
|
|
|
CP0480089
|
4-[1-(3,5-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H20Cl2N6O
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0535796
|
N-[1-[(3,4-difluorophenyl)methyl]piperidin-4-yl]-6-(trifluoromethyl)pyridazin-3-amine
Show/Hide
|
C17H17F5N4
|
1
|
| 1 |
Ki = 158 nM
|
|
|
|
CP0367294
|
1-(2-methoxyphenyl)-4-[3-[1-(4-thiophen-3-ylphenyl)triazol-4-yl]propyl]piperazine
Show/Hide
|
C26H29N5OS
|
1
|
| 1 |
Ki = 158 nM
|
|
|
|
CP0449021
|
1-((1H-indol-3-yl)methyl)-4-(4-(hexyloxy)phenyl)piperidin-4-ol
Show/Hide
|
C26H34N2O2
|
1
|
| 1 |
Ki = 159 nM
|
|
|
|
CP0513756
|
N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]thiophene-2-carboxamide
Show/Hide
|
C26H30ClN3OS
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0883761
|
(2S,4aR,10bR)-2-(4-hydroxyphenyl)-4-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline-8,9-diol hydrobromide
Show/Hide
|
C22H28BrNO3
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0375469
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N-(cyclopropylmethyl)-4-fluorobenzenesulfonamide
Show/Hide
|
C27H37FN2O3S
|
1
|
| 1 |
Ki = 160 nM
|
|
|
|
CP0445343
|
(E)-N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
|
C31H37N3O
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0380583
|
3-(1H-indol-3-yl)-1-[4-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C30H34N4O3
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0417075
|
1-[6-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 161 nM
|
|
|
|
CP0487362
|
N-(1-benzothiophen-3-ylmethyl)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-propylbutan-1-amine
Show/Hide
|
C26H33Cl2N3S
|
1
|
| 1 |
Ki = 162 nM
|
|
|
|
CP0386825
|
N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C23H26F3N5O
|
1
|
| 1 |
Ki = 162 nM
|
|
|
|
CP0474296
|
4-[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]triazol-1-yl]-N,N-dimethylaniline
Show/Hide
|
C24H32N6O
|
1
|
| 1 |
Ki = 162 nM
|
|
|
|
CP0873149
|
1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
|
| 1 |
Ki = 162 nM
|
|
|
|
CP0511136
|
N-[4-[4-(2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H33N3O2
|
1
|
| 1 |
Ki = 163 nM
|
|
|
|
CP0250704
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C25H30ClN3O3
|
1
|
| 1 |
Ki = 164 nM
|
|
|
|
CP0527898
|
N-[6-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]hexyl]-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide
Show/Hide
|
C30H33F3N4O2S2
|
1
|
| 1 |
Ki = 164 nM
|
|
|
|
CP0449025
|
3-((4-(allyloxy)-4-(4-chlorophenyl)piperidin-1-yl)methyl)-1H-indole
Show/Hide
|
C23H25ClN2O
|
1
|
| 1 |
Ki = 165 nM
|
|
|
|
CP0558696
|
1,1-dioxo-2-[5-(4-phenylpiperazin-1-yl)pentyl]-1,2-benzothiazol-3-one
Show/Hide
|
C22H27N3O3S
|
1
|
| 1 |
Ki = 165 nM
|
|
|
|
CP0501917
|
7-[(3-(4-phenylpiperazin-1-yl)propyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C26H37N3O
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0457523
|
4-[5-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
Ki = 167 nM
|
|
|
|
CP0065124
|
9H-Fluorene-2-carboxylic acid {(E)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide
Show/Hide
|
C28H27Cl2N3O
|
2
|
| 1 |
Ki = 168 nM
|
|
|
| 2 |
Ki = 198 nM
|
|
|
|
CP0231667
|
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]cyclohexanecarboxamide
Show/Hide
|
C22H35N3O2
|
1
|
| 1 |
Ki = 168 nM
|
|
|
|
CP0525901
|
(1R,2S,6R,7S)-4-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C26H34F3N3O2
|
1
|
| 1 |
Ki = 168 nM
|
|
|
|
CP0397770
|
N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]-4-(methylamino)benzamide
Show/Hide
|
C24H34N4O2
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0520078
|
N-[4-[4-(2-chlorophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H28ClN3OS
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0234731
|
4-[4-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]triazol-1-yl]-N,N-dimethylaniline
Show/Hide
|
C25H34N6O
|
1
|
| 1 |
Ki = 171 nM
|
|
|
|
CP0363247
|
3-methoxy-8-methyl-5,6,7,8,9,10,11,16-octahydrodibenzo[e,h]azacyclododecene
Show/Hide
|
C21H27NO
|
1
|
| 1 |
Ki = 172 nM
|
|
|
|
CP0454413
|
(-)-S-11-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butoxy)-N-propylnoraporphine
Show/Hide
|
C34H43N3O2
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1
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| 1 |
Ki = 174 nM
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CP0847873
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N-(Benzothiazol-2-yl)-5-(4-(2-fluorophenyl)piperazin-1-yl)pentanamide
Show/Hide
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C22H25FN4OS
|
1
|
| 1 |
Ki = 175 nM
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CP0379464
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-5-[(dimethylamino)methyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C28H39F3N8O
|
3
|
| 1 |
Ki = 176 nM
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| 2 |
Ki = 245 nM
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| 3 |
Ki = 298 nM
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CP0449017
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1-((1H-indol-3-yl)methyl)-4-(4-methoxyphenyl)piperidin-4-ol
Show/Hide
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C21H24N2O2
|
1
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| 1 |
Ki = 177 nM
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CP0424213
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2-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)-1,2-benzisothiazole-3(2H)-one 1,1-dioxide
Show/Hide
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C21H24ClN3O3S
|
2
|
| 1 |
Ki = 177 nM
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| 2 |
Ki > 10000 nM
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CP0538554
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6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[(1S)-1-phenylethyl]hexanamide
Show/Hide
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C31H39N3O2
|
1
|
| 1 |
Ki = 177 nM
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CP0553536
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N-[4-(4-phenylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C22H27N5O
|
1
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| 1 |
Ki = 178 nM
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CP0445704
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N-benzyl-6-[(2R)-2-methyl-4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 178 nM
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CP0421348
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4-[5-[[2-(4-methoxy-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
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C22H22N2O3
|
1
|
| 1 |
Ki = 178 nM
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CP0384571
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1-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
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C28H33N3O2
|
1
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| 1 |
Ki = 180 nM
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CP0481572
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N-[2-[(1S,2R)-2-[(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)methyl]cyclopropyl]ethyl]-1H-indole-2-carboxamide
Show/Hide
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C25H26N4O
|
1
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| 1 |
Ki = 182 nM
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CP0427783
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1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-amine
Show/Hide
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C20H22ClN3
|
1
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| 1 |
Ki = 184 nM
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CP0372388
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4-(4-chlorophenyl)-1-((1-hexyl-1H-indol-3-yl)methyl)piperidin-4-ol
Show/Hide
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C26H33ClN2O
|
1
|
| 1 |
Ki = 188 nM
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CP0417064
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1-[6-(4-pyrimidin-2-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
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C25H29N5O
|
1
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| 1 |
Ki = 188 nM
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CP0485814
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N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]cyclohexanecarboxamide
Show/Hide
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C28H38ClN3O
|
1
|
| 1 |
Ki = 189 nM
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CP0410753
|
1-[4-(2-methoxyphenyl)piperazin-1-yl]-4-(4-naphthalen-2-yltriazol-1-yl)butan-2-ol
Show/Hide
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C27H31N5O2
|
1
|
| 1 |
Ki = 189 nM
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CP0864251
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
Show/Hide
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C24H36Cl2N2O3
|
1
|
| 1 |
Ki = 189 nM
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CP0490048
|
5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H18N2O3S2
|
1
|
| 1 |
Ki = 190 nM
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CP0396209
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N-[[(1R,2S)-2-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclopropyl]methyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
Ki = 190 nM
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CP0416278
|
3-(5-fluoro-1H-indol-3-yl)-1-[4-[4-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C29H31FN4O2
|
1
|
| 1 |
Ki = 190 nM
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CP0391046
|
N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
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C26H31N3OS
|
1
|
| 1 |
Ki = 190 nM
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CP0425930
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N-[4-[4-(2-tert-butyl-6-cyclopropylpyrimidin-4-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C27H37N7O
|
1
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| 1 |
Ki = 191 nM
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CP0513106
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N-[4-[4-[3-cyano-5-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C24H25F3N6O
|
1
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| 1 |
Ki = 191 nM
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CP0434495
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C24H30ClN5O2
|
1
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| 1 |
Ki = 193 nM
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CP0260081
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]naphthalene-2-carboxamide
Show/Hide
|
C25H26Cl2FN3O
|
1
|
| 1 |
Ki = 195 nM
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CP0914958
|
endo-8-(1H-Indol-3-ylmethyl)-3-(2-naphthyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C26H26N2O
|
1
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| 1 |
Ki = 196 nM
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CP0473557
|
N-(9H-fluoren-2-ylmethyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]-N-propylbutan-1-amine
Show/Hide
|
C32H41N3O
|
1
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| 1 |
Ki = 196 nM
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CP0483353
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1-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
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C27H31Cl2N3O
|
1
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| 1 |
Ki = 197 nM
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|
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CP0477399
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undec-4-ene
Show/Hide
|
C28H35N5OS
|
1
|
| 1 |
Ki = 197 nM
|
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|
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CP0421765
|
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidine-4-carbonitrile
Show/Hide
|
C21H20ClN3
|
1
|
| 1 |
Ki = 199 nM
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CP0390348
|
3-fluoro-N-[8-[2-(3-propan-2-ylphenoxy)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzenesulfonamide
Show/Hide
|
C24H31FN2O3S
|
1
|
| 1 |
Ki = 199 nM
|
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CP0470410
|
(rac)-3-(3-(1-(3-(4-(Benzo[d]isothiazol-3-yl)piperazin-1-yl)-propyl)-1H-1,2,3-triazol-4-yl)propyl)-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
Show/Hide
|
C36H43N7O2S
|
1
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| 1 |
Ki = 200 nM
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CP0384372
|
N-(3-methylphenyl)-3-(4-pyridin-2-ylpiperazin-1-yl)propanamide
Show/Hide
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C19H24N4O
|
2
|
| 1 |
Ki = 200 nM
|
|
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| 2 |
Ki = 11900 nM
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CP0384375
|
N-(3-methylphenyl)-2-(4-naphthalen-1-ylpiperazin-1-yl)acetamide
Show/Hide
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C23H25N3O
|
2
|
| 1 |
Ki = 200 nM
|
|
|
| 2 |
Ki = 1489 nM
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CP0467819
|
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)azepan-4-ol
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
Ki = 201 nM
|
|
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CP0044536
|
(2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C16H25NO
|
1
|
| 1 |
Ki = 202 nM
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CP0471596
|
N-[(3R)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]quinoline-3-carboxamide
Show/Hide
|
C24H26Cl2N4O2
|
1
|
| 1 |
Ki = 202 nM
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CP0869682
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N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide hydrochloride
Show/Hide
|
C23H27Cl3N4O
|
1
|
| 1 |
Ki = 202.3 nM
|
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CP0416670
|
1-[6-[4-(4-bromophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31BrClN3O
|
1
|
| 1 |
Ki = 204 nM
|
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CP0395781
|
(+/-)-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine
Show/Hide
|
C39H50N6O2
|
1
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| 1 |
Ki = 206 nM
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CP0537420
|
4-[3-(2,3-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C17H22Cl2N6O
|
1
|
| 1 |
Ki = 206 nM
|
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CP0183414
|
(R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol
Show/Hide
|
C17H17NO
|
1
|
| 1 |
Ki = 208 nM
|
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CP0845828
|
(+/-)-3-Methyl-1,6-di-(m-tolyl)-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol hydrobromide
Show/Hide
|
C25H28BrNO2
|
1
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| 1 |
Ki = 210 nM
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CP0382130
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(11S)-5-methyl-6,11-dioxo-N-(2-pyrrolidin-1-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H23N3O3S
|
1
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| 1 |
Ki = 210 nM
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CP0576876
|
2-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C22H26Cl2N6
|
1
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| 1 |
Ki = 210 nM
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CP0919397
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1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-bromophenyl)piperidin-4-ol oxalate
Show/Hide
|
C21H22BrN3O5
|
1
|
| 1 |
Ki = 212 nM
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CP0263105
|
(13aS)-3,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolin[2,1-b]isoquinoline-2,9-diol
Show/Hide
|
C19H21NO4
|
1
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| 1 |
Ki = 214 nM
|
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CP0197218
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]-5-methoxy-1H-indole-2-carboxamide
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
Ki = 217 nM
|
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CP0416279
|
3-(5-methoxy-1H-indol-3-yl)-1-[4-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C31H36N4O4
|
1
|
| 1 |
Ki = 217 nM
|
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CP0063623
|
N-[(3S)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H31ClN4O2
|
1
|
| 1 |
Ki = 219 nM
|
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CP0496624
|
2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyrazolo[1,5-a]-pyridine
Show/Hide
|
C22H27ClN4
|
1
|
| 1 |
Ki = 220 nM
|
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CP0426435
|
4-[5-[[2-(5-methoxy-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C22H22N2O3
|
1
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| 1 |
Ki = 220 nM
|
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CP0483144
|
3-[6-[4-(2,3-dichlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H30Cl3N3O2S
|
1
|
| 1 |
Ki = 220 nM
|
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CP0417573
|
5-[4-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
|
C26H31FN4O2S
|
1
|
| 1 |
Ki = 223 nM
|
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CP0880730
|
endo-8-(1H-Indazol-3-ylmethyl)-3-(4-chlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C21H22ClN3O
|
1
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| 1 |
Ki = 225 nM
|
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CP0530032
|
(1S,2R,6S,7R)-4-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
|
C25H34ClN3O2
|
1
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| 1 |
Ki = 225 nM
|
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CP0515023
|
2-[4-[4-[(4-chlorophenyl)-phenylmethyl]-1,4-diazepan-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C30H32ClN3O2
|
1
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| 1 |
Ki = 226 nM
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CP0451508
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N-[2-[bis(4-fluorophenyl)methylsulfanyl]ethyl]-3-phenylpropan-1-amine
Show/Hide
|
C24H25F2NS
|
1
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| 1 |
Ki = 228 nM
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CP0451281
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4-[1-(2,5-dichlorophenoxy)butyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C18H24Cl2N6O
|
1
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| 1 |
Ki = 229 nM
|
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CP0576365
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1-(3-chlorophenyl)-4-[6-(sulfamoylamino)hexyl]piperazine
Show/Hide
|
C16H27ClN4O2S
|
1
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| 1 |
Ki = 229 nM
|
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CP0190973
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-5-methoxy-1H-indole-2-carboxamide
Show/Hide
|
C24H27Cl2FN4O2
|
1
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| 1 |
Ki = 230 nM
|
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CP0038689
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(4aS,5R,10bR)-5-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[h]isoquinoline-7,8-diol
Show/Hide
|
C19H21NO2
|
1
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| 1 |
Ki = 230 nM
|
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CP0375470
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N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N-(cyclopropylmethyl)-1-methylpyrazole-4-sulfonamide
Show/Hide
|
C25H38N4O3S
|
1
|
| 1 |
Ki = 230 nM
|
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CP0167921
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1-(3-chloro-5-ethyl-2-methoxyphenyl)-4-methylpiperazine
Show/Hide
|
C14H21ClN2O
|
1
|
| 1 |
Ki = 233 nM
|
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CP0445985
|
3-methyl-N-[(4-phenylpiperidin-1-yl)methyl]benzamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
Ki = 235 nM
|
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|
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CP0470894
|
(R)-(-)-2-methoxy-11-hydroxyaporphine
Show/Hide
|
C18H19NO2
|
1
|
| 1 |
Ki = 235 nM
|
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|
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CP0568128
|
6-[4-(3-chlorophenyl)piperazin-1-yl]hexylurea
Show/Hide
|
C17H27ClN4O
|
1
|
| 1 |
Ki = 235 nM
|
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CP0160210
|
N-[4-[4-(2-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28ClN3O
|
1
|
| 1 |
Ki = 238 nM
|
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CP0432567
|
1,1-dioxo-2-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]-1,2-benzothiazol-3-one
Show/Hide
|
C22H28N4O3S
|
1
|
| 1 |
Ki = 239 nM
|
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CP0411142
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(11S)-N-[(4-bromophenyl)methyl]-5-methyl-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C22H17BrN2O3S
|
1
|
| 1 |
Ki = 240 nM
|
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CP0430225
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7-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 240 nM
|
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CP0294038
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N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C24H28FN3O2S
|
1
|
| 1 |
Ki = 241 nM
|
|
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CP0445710
|
N-[(1R)-1-(4-cyanophenyl)ethyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H38N4O2
|
1
|
| 1 |
Ki = 243 nM
|
|
|
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CP0476100
|
N-benzyl-6-[(2S)-2-methyl-4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
Ki = 243 nM
|
|
|
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CP0410752
|
1-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-(4-quinolin-6-yltriazol-1-yl)butan-2-ol
Show/Hide
|
C25H26Cl2N6O
|
1
|
| 1 |
Ki = 244 nM
|
|
|
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CP0377326
|
7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol
Show/Hide
|
C25H31N3O
|
1
|
| 1 |
Ki = 245 nM
|
|
|
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CP0416667
|
1-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H30Cl3N3O
|
1
|
| 1 |
Ki = 246 nM
|
|
|
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CP0126478
|
N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H30ClFN4O
|
1
|
| 1 |
Ki = 247 nM
|
|
|
|
CP0377890
|
US8748608, 19
Show/Hide
|
C29H33N3O3
|
1
|
| 1 |
Ki = 249 nM
|
|
|
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CP0461813
|
[(1S,2R,5R,6R,7R)-3-benzyl-2-phenyl-7-pyrrolidin-1-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0384374
|
2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)-N-(m-tolyl)acetamide
Show/Hide
|
C19H23N3O
|
3
|
| 1 |
Ki = 251 nM
|
|
|
| 2 |
Ki = 2900 nM
|
|
|
| 3 |
Ki = 6250 nM
|
|
|
|
CP0398688
|
N-[4-[2-[[3-(benzenesulfonyl)-6,7-dihydrocyclobuta[e]indol-7-yl]methyl-methylamino]ethyl]phenyl]acetamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0471200
|
N-[4-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C34H34ClN3O
|
1
|
| 1 |
Ki = 252 nM
|
|
|
|
CP0545009
|
3-[6-[4-(3-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene 2,2-dioxide
Show/Hide
|
C25H33ClN4O2S
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0919407
|
1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-(methylthio)phenyl)piperidin-4-ol oxalate
Show/Hide
|
C22H25N3O5S
|
1
|
| 1 |
Ki = 254 nM
|
|
|
|
CP0483352
|
3-[6-[4-(3,4-dichlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C26H30Cl3N3O2S
|
1
|
| 1 |
Ki = 254 nM
|
|
|
|
CP0514793
|
2-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
|
C22H26ClN3O3S
|
1
|
| 1 |
Ki = 254 nM
|
|
|
|
CP0945583
|
3-{2-Hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H32N4O4
|
1
|
| 1 |
Ki = 256 nM
|
|
|
|
CP0427967
|
N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]cyclohexanecarboxamide
Show/Hide
|
C28H37N3O
|
1
|
| 1 |
Ki = 258 nM
|
|
|
|
CP0109608
|
N-[3-hydroxy-4-(4-naphthalen-1-ylpiperazin-1-yl)butyl]quinoline-3-carboxamide
Show/Hide
|
C28H30N4O2
|
1
|
| 1 |
Ki = 258 nM
|
|
|
|
CP0445705
|
6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[[4-(3-morpholin-4-ylpropoxy)phenyl]methyl]hexanamide
Show/Hide
|
C37H50N4O4
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0001212
|
1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
Show/Hide
|
C23H29N5OS
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0569536
|
[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C25H34N4O2
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0122652
|
3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C30H33FN4O3
|
1
|
| 1 |
Ki = 261 nM
|
|
|
|
CP0554865
|
4-thiophen-3-yl-N-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
|
C26H28F3N3OS
|
1
|
| 1 |
Ki = 261 nM
|
|
|
|
CP0392147
|
3,6-dimethyl-4,5,6,7,8,13-hexahydro-3H-pyrrolo[2,3-f][3]benzazecine
Show/Hide
|
C17H22N2
|
2
|
| 1 |
Ki = 264 nM
|
|
|
| 2 |
Ki = 712 nM
|
|
|
|
CP0402710
|
(S)-N*6*-[2-(4-Biphenyl-4-yl-piperazin-1-yl)-ethyl]-N*6*-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine
Show/Hide
|
C28H37N5S
|
1
|
| 1 |
Ki = 264 nM
|
|
|
|
CP0852965
|
3-{2-Hydroxy-3-[4-(2-cyanophenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-2-yl)imidazolidine-2,4-dione
Show/Hide
|
C28H29N5O3
|
1
|
| 1 |
Ki = 264 nM
|
|
|
|
CP0417091
|
3-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide
Show/Hide
|
C26H30N4O4S
|
1
|
| 1 |
Ki = 264 nM
|
|
|
|
CP0476869
|
1-(2-methoxyphenyl)-4-methylpiperazine
Show/Hide
|
C12H18N2O
|
1
|
| 1 |
Ki = 265 nM
|
|
|
|
CP0548044
|
5-(4-bromophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H30BrClN4O4
|
1
|
| 1 |
Ki = 267 nM
|
|
|
|
CP0392875
|
[(12R)-11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaen-12-yl]methanol
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 268 nM
|
|
|
|
CP0470858
|
3-[2-[4-(3-phenylpyridin-2-yl)piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C28H31F3N4O2
|
1
|
| 1 |
Ki = 268 nM
|
|
|
|
CP0417544
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]quinoline-3-carboxamide
Show/Hide
|
C24H26Cl2N4O2
|
2
|
| 1 |
Ki = 268 nM
|
|
|
| 2 |
Ki = 321 nM
|
|
|
|
CP0411950
|
(-)-(S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine
Show/Hide
|
C25H34N6S
|
1
|
| 1 |
Ki = 269 nM
|
|
|
|
CP0478474
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-(9H-fluoren-2-ylmethyl)-N-propylbutan-1-amine
Show/Hide
|
C31H37Cl2N3
|
1
|
| 1 |
Ki = 269 nM
|
|
|
|
CP0411953
|
5-(3-fluorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H30ClFN4O4
|
1
|
| 1 |
Ki = 269 nM
|
|
|
|
CP0402706
|
(-)-(S)-N6-Propyl-N6-(2-(4-(4-(pyridin-4-yl)phenyl)piperazin-1-yl)-ethyl)-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine
Show/Hide
|
C27H36N6S
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0451282
|
4-[1-(3,5-dichlorophenoxy)pentyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C19H26Cl2N6O
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0417067
|
2-[6-[4-(3-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
|
C29H33N3O3
|
1
|
| 1 |
Ki = 271 nM
|
|
|
|
CP0483747
|
1-(2-methoxyphenyl)-4-[3-[1-(2-methoxyphenyl)triazol-4-yl]propyl]piperazine
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 272 nM
|
|
|
|
CP0852963
|
3-{3-[4-(Diphenylmethyl)piperazin-1-yl]-2-hydroxypropyl}-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione
Show/Hide
|
C34H36N4O3
|
1
|
| 1 |
Ki = 273 nM
|
|
|
|
CP0207473
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methoxy-1-benzofuran-2-carboxamide
Show/Hide
|
C25H30FN3O4
|
1
|
| 1 |
Ki = 274 nM
|
|
|
|
CP0273713
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-5-methoxy-1-benzofuran-2-carboxamide
Show/Hide
|
C24H26Cl2FN3O3
|
1
|
| 1 |
Ki = 279 nM
|
|
|
|
CP0852047
|
endo-8-(Benzothien-3-ylmethyl)-3-(2,3-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H21Cl2NOS
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0407660
|
5-(4-fluorophenyl)-N-[4-[4-(2-methoxyphenyl)-1,4-diazepan-1-yl]butyl]thiophene-2-carboxamide
Show/Hide
|
C27H32FN3O2S
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0375464
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N,1-dimethylpyrazole-4-sulfonamide
Show/Hide
|
C22H34N4O3S
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0277136
|
US8748608, 18
Show/Hide
|
C27H32N4O3
|
2
|
| 1 |
Ki = 284 nM
|
|
|
| 2 |
Ki = 1090 nM
|
|
|
|
CP0424211
|
1-(4-(4-phenyl-1-piperazinyl)butyl)indolin-2-one
Show/Hide
|
C23H29N3O2
|
2
|
| 1 |
Ki = 286 nM
|
|
|
| 2 |
Ki = 405 nM
|
|
|
|
CP0393635
|
1-[3-[4-(2-phenylethyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C25H32N2O
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0380862
|
(11S)-5-ethyl-N-[(1R)-1-naphthalen-2-ylethyl]-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C28H24N2O3S
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0385587
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-3-fluoro-N-methylbenzenesulfonamide
Show/Hide
|
C24H33FN2O3S
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0475836
|
(-)-S-11-((1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine
Show/Hide
|
C37H46N6O2
|
1
|
| 1 |
Ki = 293 nM
|
|
|
|
CP0445706
|
N-[(4-cyanophenyl)methyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C31H36N4O2
|
1
|
| 1 |
Ki = 293 nM
|
|
|
|
CP0507071
|
6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[(1R)-1-phenylethyl]hexanamide
Show/Hide
|
C31H39N3O2
|
1
|
| 1 |
Ki = 295 nM
|
|
|
|
CP0853989
|
5-(4-Fluorophenyl)-3-{2-hydroxy-3-[4-(naphthalen-1-yl)-piperazin-1-yl]propyl}-5-methylimidazolidine-2,4-dione
Show/Hide
|
C27H29FN4O3
|
1
|
| 1 |
Ki = 295 nM
|
|
|
|
CP0436454
|
[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-[(3R)-dithiolan-3-yl]pentanoate
Show/Hide
|
C27H33NO2S2
|
1
|
| 1 |
Ki = 296 nM
|
|
|
|
CP0464096
|
US10913711, Compound 10d
Show/Hide
|
C22H28F2N2O2S
|
1
|
| 1 |
Ki = 298 nM
|
|
|
|
CP0873148
|
1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
Show/Hide
|
C20H27Cl3N2O
|
1
|
| 1 |
Ki = 299 nM
|
|
|
|
CP0377527
|
5-ethyl-6,11-diketo-N-p-anisyl-benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C24H22N2O4S
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0122857
|
(R)-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydroxybutyl)-1H-indole-2-carboxamide
Show/Hide
|
C23H26Cl2N4O2
|
2
|
| 1 |
Ki = 300 nM
|
|
|
| 2 |
Ki = 433 nM
|
|
|
|
CP0412015
|
5-(2-fluorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H30ClFN4O4
|
1
|
| 1 |
Ki = 301 nM
|
|
|
|
CP0273714
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-5-methoxy-1H-indole-2-carboxamide
Show/Hide
|
C25H31FN4O3
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0133068
|
N-[4-[4-(2,3-dimethylphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C27H33N3O
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0397956
|
3-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H25Cl2FN4O3
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0430227
|
5-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0477980
|
3-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methyl-5-phenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C25H33ClN4O4
|
1
|
| 1 |
Ki = 303 nM
|
|
|
|
CP0478413
|
3-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C27H31ClF3N3O2S
|
1
|
| 1 |
Ki = 304 nM
|
|
|
|
CP0377051
|
N-[(1S)-1-(4-cyanophenyl)ethyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H38N4O2
|
1
|
| 1 |
Ki = 308 nM
|
|
|
|
CP0891094
|
7-(4-(4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C27H31ClN4O7
|
1
|
| 1 |
Ki = 309 nM
|
|
|
|
CP0411140
|
(11S)-5-methyl-6,11-dioxo-N-(pyridin-3-ylmethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H17N3O3S
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0309749
|
N-[4-[4-(2-fluorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28FN3O
|
1
|
| 1 |
Ki = 310 nM
|
|
|
|
CP0501038
|
N-[4-[4-[bis(2-methoxyphenyl)methyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C34H39N3O3
|
1
|
| 1 |
Ki = 313 nM
|
|
|
|
CP0495123
|
4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-N-(naphthalen-2-ylmethyl)-N-propylbutan-1-amine
Show/Hide
|
C28H35Cl2N3
|
1
|
| 1 |
Ki = 313 nM
|
|
|
|
CP0417545
|
N-[(3S)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]quinoline-3-carboxamide
Show/Hide
|
C24H26Cl2N4O2
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0485739
|
(2S)-1-[4-(2,3-dichlorophenyl)piperazin-1-yl]propan-2-ol
Show/Hide
|
C13H18Cl2N2O
|
1
|
| 1 |
Ki = 317 nM
|
|
|
|
CP0462945
|
5-chloro-N-[1-(2-phenoxyethyl)pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H19ClN2O3S2
|
1
|
| 1 |
Ki = 318 nM
|
|
|
|
CP0065116
|
US8748608, 17
Show/Hide
|
C28H29Cl2N3O2
|
1
|
| 1 |
Ki = 319 nM
|
|
|
|
CP0384691
|
1-[6-[4-(2-fluorophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C27H31ClFN3O
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0517109
|
4-[1-(2,5-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C17H22Cl2N6O
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0376759
|
N-[[4-(methoxymethoxy)phenyl]methyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C32H41N3O4
|
1
|
| 1 |
Ki = 321 nM
|
|
|
|
CP0095896
|
2-cyclohexyl-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]acetamide
Show/Hide
|
C23H37N3O2
|
1
|
| 1 |
Ki = 322 nM
|
|
|
|
CP0413781
|
N-[1-[2-(2-cyclopentylphenoxy)ethyl]piperidin-4-yl]-3-fluorobenzenesulfonamide
Show/Hide
|
C24H31FN2O3S
|
1
|
| 1 |
Ki = 322 nM
|
|
|
|
CP0371914
|
1-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-indolin-2-one
Show/Hide
|
C23H26F3N3O
|
2
|
| 1 |
Ki = 323 nM
|
|
|
| 2 |
Ki = 416 nM
|
|
|
|
CP0535381
|
N-[(3,3-diphenyl-1,4-dioxan-2-yl)methyl]-2-(2-methoxyphenoxy)ethanamine
Show/Hide
|
C26H29NO4
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0403509
|
N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-4-fluoro-N-methylbenzenesulfonamide
Show/Hide
|
C24H33FN2O3S
|
1
|
| 1 |
Ki = 324 nM
|
|
|
|
CP0452532
|
(12R)-5-amino-11-methyl-6-thia-4,11-diazapentacyclo[10.7.1.03,7.08,20.014,19]icosa-1,3(7),4,8(20),14(19),15,17-heptaene-17,18-diol
Show/Hide
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C18H17N3O2S
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1
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| 1 |
Ki = 328 nM
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CP0156829
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]-5-fluoro-1H-indole-2-carboxamide
Show/Hide
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C23H25Cl2FN4O2
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1
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| 1 |
Ki = 328 nM
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CP0063614
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N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
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C25H29ClFN3O2
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1
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| 1 |
Ki = 328 nM
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CP0038049
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N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
Show/Hide
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C24H28FN3O3
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1
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| 1 |
Ki = 329 nM
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CP0438623
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4-[(2-chlorophenyl)sulfanylmethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C15H19ClN6S
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1
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| 1 |
Ki = 329 nM
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CP0386830
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1H-benzimidazole-2-carboxamide
Show/Hide
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C25H32F3N7O
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1
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| 1 |
Ki = 336 nM
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CP0495706
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3-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
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C26H31Cl2N3O2S
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1
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| 1 |
Ki = 336 nM
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CP0400251
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1-benzyl-N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]piperidine-4-carboxamide
Show/Hide
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C30H43F3N6O
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1
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| 1 |
Ki = 337 nM
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CP0438516
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7-[(E)-4-[(2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]but-2-enoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C23H28N4O3
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1
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| 1 |
Ki = 341 nM
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CP0436564
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[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] 5-[(3S)-dithiolan-3-yl]pentanoate
Show/Hide
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C27H33NO2S2
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1
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| 1 |
Ki = 342 nM
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CP0376742
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3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
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C29H32F3N3O2
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1
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| 1 |
Ki = 345 nM
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CP0282475
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3-(N-propylpiperidin-4-yl)phenol
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C14H21NO
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2
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| 1 |
Ki = 349 nM
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| 2 |
Ki = 2570 nM
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CP0427419
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2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyrazolo[1,5-a]pyridine
Show/Hide
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C19H22N4O
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2
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| 1 |
Ki = 350 nM
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| 2 |
Ki = 3600 nM
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CP0426138
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(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-amine
Show/Hide
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C19H22N2
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1
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| 1 |
Ki = 352 nM
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CP0377602
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N-[2-[(7-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-[3-(4-phenylpiperazin-1-yl)propyl]amino]ethyl]benzamide
Show/Hide
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C32H40N4O2
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1
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| 1 |
Ki = 354 nM
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CP0551591
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4-[3-(3,4-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22Cl2N6O
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1
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| 1 |
Ki = 356 nM
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CP0385628
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N-[1-[2-(2-tert-butylphenoxy)ethyl]piperidin-4-yl]-N-methylbenzenesulfonamide
Show/Hide
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C24H34N2O3S
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1
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| 1 |
Ki = 360 nM
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CP0410601
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N-[4-[4-(2,6-ditert-butylpyrimidin-4-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C28H41N7O
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1
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| 1 |
Ki = 361 nM
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CP0556695
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N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C25H32ClN3O5
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1
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| 1 |
Ki = 364 nM
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CP0386820
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N-[4-[4-(2-tert-butyl-6-methylpyrimidin-4-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C25H35N7O
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1
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| 1 |
Ki = 366 nM
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CP0426411
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5-(4-chlorophenyl)-3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
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C24H30Cl2N4O4
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1
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| 1 |
Ki = 366 nM
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CP0542765
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2-N-[4-(4-phenylpiperazin-1-yl)butyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C17H26N8
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1
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| 1 |
Ki = 366 nM
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CP0443918
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2-(1H-indol-3-yl)-N-methyl-N-[(5-phenylfuran-2-yl)methyl]ethanamine
Show/Hide
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C22H22N2O
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1
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| 1 |
Ki = 368 nM
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CP0471354
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4-[1-(3,5-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22Cl2N6O
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1
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| 1 |
Ki = 368 nM
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CP0473054
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(1S,2R,6S,7R)-4-[6-[4-(4-chlorophenyl)piperazin-1-yl]hexyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
Show/Hide
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C25H34ClN3O2
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1
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| 1 |
Ki = 370 nM
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CP0364137
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N-[4-[4-(3-hydroxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C25H29N3O2
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1
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| 1 |
Ki = 373 nM
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CP0371908
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1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indolin-2-one
Show/Hide
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C22H26ClN3O
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2
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| 1 |
Ki = 375 nM
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| 2 |
Ki = 1747 nM
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CP0476102
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6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-N-[[4-(2-morpholin-4-ylethoxy)phenyl]methyl]hexanamide
Show/Hide
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C36H48N4O4
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1
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| 1 |
Ki = 375 nM
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CP0549040
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4-[1-(2,5-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H20Cl2N6O
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1
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| 1 |
Ki = 375 nM
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CP0249646
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4-[5-[[2-(5-fluoro-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
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C21H19FN2O2
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1
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| 1 |
Ki = 376 nM
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CP0451283
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4-[1-(3,5-dichlorophenoxy)butyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C18H24Cl2N6O
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1
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| 1 |
Ki = 377 nM
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CP0190972
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-4-pyridin-2-ylbenzamide
Show/Hide
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C26H27Cl2FN4O
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1
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| 1 |
Ki = 378 nM
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CP0449014
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1-((1H-indol-3-yl)methyl)-4-(2-chlorophenyl)piperidin-4-ol
Show/Hide
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C20H21ClN2O
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1
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| 1 |
Ki = 382 nM
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CP0346837
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8-methyl-5,6,7,8,9,10,11,16-octahydrodibenzo[e,h]azacyclododecene-3-ol
Show/Hide
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C20H25NO
|
1
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| 1 |
Ki = 382 nM
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CP0207472
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N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-4-pyridin-2-ylbenzamide
Show/Hide
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C27H31FN4O2
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1
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| 1 |
Ki = 390 nM
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CP0557796
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3-[5-[[2-(5-methoxy-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
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C22H22N2O3
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1
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| 1 |
Ki = 391 nM
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CP0362715
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1-Benzyl-4-[3-(methylsulfonyl)phenyl]piperidine
Show/Hide
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C19H23NO2S
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2
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| 1 |
Ki = 392 nM
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| 2 |
Ki = 841 nM
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CP0377050
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3-[2-[4-[3-(4-fluorophenyl)pyridin-2-yl]piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
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C28H30F4N4O2
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1
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| 1 |
Ki = 393 nM
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CP0454411
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(+/-)-N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)-N-(3-(N-propylnoraporphin-11-yloxy)-propyl)methanesulfonamide
Show/Hide
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C37H50N4O4S
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1
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| 1 |
Ki = 399 nM
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CP0420078
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N-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C26H31N3O
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1
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| 1 |
Ki = 404 nM
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CP0444754
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4-[3-(2,5-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22Cl2N6O
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1
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| 1 |
Ki = 413 nM
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CP0874391
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3-{2-Hydroxy-3-[4-(2-cyanophenyl)piperazin-1-yl]propyl}-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione
Show/Hide
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C28H29N5O3
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1
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| 1 |
Ki = 416 nM
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CP0448725
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4-[4-[2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
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C26H31FN4O2S
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1
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| 1 |
Ki = 418 nM
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CP0568683
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4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
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C25H31N9
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1
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| 1 |
Ki = 418 nM
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CP0376750
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N-[[4-(2-hydroxyethoxy)phenyl]methyl]-6-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
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C32H41N3O4
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1
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| 1 |
Ki = 419 nM
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CP0190971
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N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
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C24H29FN4O2
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1
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| 1 |
Ki = 421 nM
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CP0517110
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4-[1-(2,3-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C17H22Cl2N6O
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1
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| 1 |
Ki = 421 nM
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CP0381747
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1-[4-(2-methoxyphenyl)piperazin-1-yl]-4-(4-quinolin-6-yltriazol-1-yl)butan-2-ol
Show/Hide
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C26H30N6O2
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1
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| 1 |
Ki = 424 nM
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CP0433590
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1-(2,3-dichlorophenyl)-4-[4-[1-(9H-fluoren-2-yl)triazol-4-yl]butyl]piperazine
Show/Hide
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C29H29Cl2N5
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1
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| 1 |
Ki = 424 nM
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CP0530038
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N-[4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-hydroxybutyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C24H30ClN3O4
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1
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| 1 |
Ki = 424 nM
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CP0439809
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(E)-N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
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C30H33N3O
|
1
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| 1 |
Ki = 429 nM
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CP0298955
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1-Benzyl-4-[3-(methylsulfonyl)phenyl]piperazine
Show/Hide
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C18H22N2O2S
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2
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| 1 |
Ki = 431 nM
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| 2 |
Ki = 1923 nM
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CP0417066
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1-[6-[4-(2-nitrophenyl)piperazin-1-yl]hexyl]benzo[cd]indol-2-one
Show/Hide
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C27H30N4O3
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1
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| 1 |
Ki = 431 nM
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CP0444753
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4-[1-(2,3-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H20Cl2N6O
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1
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| 1 |
Ki = 432 nM
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CP0426894
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N-[4-(4-benzhydrylpiperazin-1-yl)butyl]cyclohexanecarboxamide
Show/Hide
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C28H39N3O
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1
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| 1 |
Ki = 435 nM
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CP0386822
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyrimidine-2-carboxamide
Show/Hide
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C24H31F3N8O
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1
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| 1 |
Ki = 436 nM
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CP0449018
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1-((1H-indazol-3-yl)methyl)-4-(3,4-dichlorophenyl)piperidin-4-ol
Show/Hide
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C19H19Cl2N3O
|
1
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| 1 |
Ki = 438 nM
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CP0466465
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4-[5-[[2-(6-fluoro-1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
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C21H19FN2O2
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1
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| 1 |
Ki = 446 nM
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CP0378578
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyrazine-2-carboxamide
Show/Hide
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C24H31F3N8O
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1
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| 1 |
Ki = 450 nM
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CP0426895
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N-[4-(4-benzhydrylpiperazin-1-yl)butyl]naphthalene-2-carboxamide
Show/Hide
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C32H35N3O
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1
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| 1 |
Ki = 457 nM
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CP0489929
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1-[3-(4-phenylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C23H28N2O
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1
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| 1 |
Ki = 457.09 nM
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CP0038047
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C23H24Cl2FN3OS
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1
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| 1 |
Ki = 472 nM
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CP0520091
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N-[[(1R,2S)-2-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclopropyl]methyl]-1H-indole-2-carboxamide
Show/Hide
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C25H26N4O
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1
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| 1 |
Ki = 476 nM
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CP0520591
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3-amino-N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]thieno[2,3-b]pyridine-2-carboxamide
Show/Hide
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C25H32F3N7OS
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1
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| 1 |
Ki = 481 nM
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CP0071764
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N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]morpholine-4-carboxamide
Show/Hide
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C20H32N4O3
|
1
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| 1 |
Ki = 482 nM
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CP0115686
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N-[4-[2-(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]-1H-indole-2-carboxamide
Show/Hide
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C27H30N4O
|
1
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| 1 |
Ki = 485 nM
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CP0883762
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(+/-)-trans-2-(4-Hydroxyphenyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline-8,9-diol Hydrobromide
Show/Hide
|
C19H22BrNO3
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1
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| 1 |
Ki = 490 nM
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CP0396168
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3-(4-butylpiperazin-1-yl)benzonitrile
Show/Hide
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C15H21N3
|
1
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| 1 |
Ki = 493 nM
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CP0567761
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4-[1-(2,3-dichlorophenoxy)butyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C18H24Cl2N6O
|
1
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| 1 |
Ki = 495 nM
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CP0384692
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1-[6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
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| 1 |
Ki = 496 nM
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CP0445341
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N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]thiophene-2-carboxamide
Show/Hide
|
C26H29N3OS
|
1
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| 1 |
Ki = 497 nM
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CP0480662
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3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5,5-diphenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C29H33ClN4O4
|
1
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| 1 |
Ki = 497 nM
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CP0135185
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4-[5-[[2-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C20H18FN3O2
|
1
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| 1 |
Ki = 505 nM
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CP0475930
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2-[4-[3-[4-(4-bromophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
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C24H27BrClN5O3
|
1
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| 1 |
Ki = 506 nM
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CP0382740
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4-(4-methylpiperazin-1-yl)-6-(phenylselanylmethyl)-1,3,5-triazin-2-amine
Show/Hide
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C15H20N6Se
|
1
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| 1 |
Ki = 506 nM
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CP0517111
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4-[1-(2,3-dichlorophenoxy)pentyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C19H26Cl2N6O
|
1
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| 1 |
Ki = 506 nM
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CP0378665
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7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene-12-ol
Show/Hide
|
C19H23NO
|
1
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| 1 |
Ki = 518 nM
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CP0402157
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4-[1-(2-chlorophenyl)sulfanylethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H21ClN6S
|
1
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| 1 |
Ki = 520 nM
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CP0046432
|
N-[(4-cyanophenyl)methyl]-6-[4-[4-fluoro-2-(4-methoxyphenyl)phenyl]piperazin-1-yl]hexanamide
Show/Hide
|
C31H35FN4O2
|
1
|
| 1 |
Ki = 522 nM
|
|
|
|
CP0484847
|
3,4-difluoro-N-[1-[2-(3-fluorophenoxy)ethyl]pyrrolidin-3-yl]benzenesulfonamide
Show/Hide
|
C18H19F3N2O3S
|
1
|
| 1 |
Ki = 523 nM
|
|
|
|
CP0411640
|
1-[3-(4-pentylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H34N2O
|
1
|
| 1 |
Ki = 524.81 nM
|
|
|
|
CP0258057
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C23H25Cl2FN4O
|
1
|
| 1 |
Ki = 526 nM
|
|
|
|
CP0378576
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-3-[(dimethylamino)methyl]-1H-indole-2-carboxamide
Show/Hide
|
C29H40F3N7O
|
1
|
| 1 |
Ki = 527 nM
|
|
|
|
CP0480949
|
(11S)-N-[(1R)-1-(4-bromophenyl)ethyl]-5-ethyl-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C24H21BrN2O3S
|
1
|
| 1 |
Ki = 530 nM
|
|
|
|
CP0412016
|
2-[4-[3-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)-2-hydroxypropyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
|
C29H30ClN5O3
|
1
|
| 1 |
Ki = 534 nM
|
|
|
|
CP0376747
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-(3-phenylpyridin-2-yl)piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H31N5O2
|
1
|
| 1 |
Ki = 537 nM
|
|
|
|
CP0565213
|
N-[4-[4-(6-ethyl-1,3-benzodioxol-5-yl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H32N4O4
|
1
|
| 1 |
Ki = 537 nM
|
|
|
|
CP0935609
|
endo-8-(1H-Indol-3-ylmethyl)-3-(2,3-dichlorophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C22H22Cl2N2O
|
1
|
| 1 |
Ki = 545 nM
|
|
|
|
CP0467820
|
1-((1H-indazol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
Show/Hide
|
C19H20ClN3O
|
1
|
| 1 |
Ki = 548 nM
|
|
|
|
CP0919167
|
endo-8-(5-Methoxy-1H-indol-3-ylmethyl)-3-(4-methylthiophenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C24H28N2O2S
|
1
|
| 1 |
Ki = 554 nM
|
|
|
|
CP0427968
|
2-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
Ki = 559 nM
|
|
|
|
CP0545013
|
2-[[4-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]cyclohexyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
|
C24H30ClN5O
|
1
|
| 1 |
Ki = 559 nM
|
|
|
|
CP0455245
|
3-chloro-N-[[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
|
C20H24ClFN2O3S
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0870327
|
endo-8-(1H-Indol-3-ylmethyl)-3-(4-(methylthio)phenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C23H26N2OS
|
1
|
| 1 |
Ki = 565 nM
|
|
|
|
CP0382746
|
4-[1-(3-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 566 nM
|
|
|
|
CP0443914
|
N-[[5-(4-chlorophenyl)furan-2-yl]methyl]-2-(5-methoxy-1H-indol-3-yl)ethanamine
Show/Hide
|
C22H21ClN2O2
|
1
|
| 1 |
Ki = 571 nM
|
|
|
|
CP0386824
|
N-[4-(4-quinolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H28N6O
|
1
|
| 1 |
Ki = 572 nM
|
|
|
|
CP0551590
|
4-[1-(3,4-dichlorophenoxy)propyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C17H22Cl2N6O
|
1
|
| 1 |
Ki = 580 nM
|
|
|
|
CP0454990
|
N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C32H34ClN3O
|
1
|
| 1 |
Ki = 587 nM
|
|
|
|
CP0463440
|
(2R)-1-[4-(2,3-dichlorophenyl)piperazin-1-yl]butan-2-ol
Show/Hide
|
C14H20Cl2N2O
|
1
|
| 1 |
Ki = 588 nM
|
|
|
|
CP0477826
|
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H33N3OS
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0545408
|
[4-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]-pyridin-2-ylmethanone
Show/Hide
|
C24H33N5O2
|
1
|
| 1 |
Ki = 590 nM
|
|
|
|
CP0426888
|
2-[4-(4-benzhydrylpiperazin-1-yl)butyl]isoindole-1,3-dione
Show/Hide
|
C29H31N3O2
|
1
|
| 1 |
Ki = 598 nM
|
|
|
|
CP0473216
|
(-)-S-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine
Show/Hide
|
C37H46N6O2
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0531665
|
3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-chlorophenyl)-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C30H34Cl2N4O3
|
1
|
| 1 |
Ki = 601 nM
|
|
|
|
CP0384370
|
N-(3-ethylphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C19H24N4O
|
2
|
| 1 |
Ki = 603 nM
|
|
|
| 2 |
Ki > 50000 nM
|
|
|
|
CP0410751
|
4-[4-(9H-fluoren-2-yl)triazol-1-yl]-1-[4-(2-methoxyphenyl)piperazin-1-yl]butan-2-ol
Show/Hide
|
C30H33N5O2
|
1
|
| 1 |
Ki = 607 nM
|
|
|
|
CP0887642
|
7-(4-(3-Methyl-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)butoxy)-3,4-dihydro-quinolin-2(1H)-one oxalate
Show/Hide
|
C29H36N4O7
|
1
|
| 1 |
Ki = 611 nM
|
|
|
|
CP0500980
|
(+)-R-11-((1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine
Show/Hide
|
C37H46N6O2
|
1
|
| 1 |
Ki = 616 nM
|
|
|
|
CP0509473
|
N-[4-[4-[bis(2-methoxyphenyl)methyl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C32H37N3O3S
|
1
|
| 1 |
Ki = 619 nM
|
|
|
|
CP0135681
|
1-(3-chloro-5-ethyl-2-methoxyphenyl)piperazine
Show/Hide
|
C13H19ClN2O
|
1
|
| 1 |
Ki = 619 nM
|
|
|
|
CP0435207
|
N-[4-(4-benzhydrylpiperazin-1-yl)butyl]thiophene-2-carboxamide
Show/Hide
|
C26H31N3OS
|
1
|
| 1 |
Ki = 621 nM
|
|
|
|
CP0383352
|
4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amino}-butyronitrile
Show/Hide
|
C27H36N4O
|
1
|
| 1 |
Ki = 622 nM
|
|
|
|
CP0434739
|
N-[3-[2-[[(1R,2S)-2-(4-chlorophenyl)cyclopropyl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
|
C29H33ClN2O2
|
1
|
| 1 |
Ki = 623 nM
|
|
|
|
CP0445345
|
N-[4-[4-[(2-methoxyphenyl)-phenylmethyl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H35N3O2S
|
1
|
| 1 |
Ki = 626 nM
|
|
|
|
CP0573228
|
[4-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]piperazin-1-yl]-(1-methylindazol-3-yl)methanone
Show/Hide
|
C26H34N6O2
|
1
|
| 1 |
Ki = 630 nM
|
|
|
|
CP0507070
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C29H32N4O2
|
1
|
| 1 |
Ki = 631 nM
|
|
|
|
CP0426890
|
N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C31H35N3OS
|
1
|
| 1 |
Ki = 633 nM
|
|
|
|
CP0434347
|
2-N-[2-(4-phenylpiperazin-1-yl)ethyl]-2-N-propyl-1,2,3,4-tetrahydronaphthalene-2,7-diamine
Show/Hide
|
C25H36N4
|
1
|
| 1 |
Ki = 638 nM
|
|
|
|
CP0378422
|
6-[(2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino]-5,6,7,8-tetrahydronaphthalen-2-ol
Show/Hide
|
C25H35N3O
|
1
|
| 1 |
Ki = 649 nM
|
|
|
|
CP0523746
|
(E)-N-[4-(4-benzhydrylpiperazin-1-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
|
C30H35N3O
|
1
|
| 1 |
Ki = 652 nM
|
|
|
|
CP0386828
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-6-chloroimidazo[1,2-b]pyridazine-2-carboxamide
Show/Hide
|
C24H30ClF3N8O
|
1
|
| 1 |
Ki = 655 nM
|
|
|
|
CP0402058
|
4-(4-methylpiperazin-1-yl)-6-(1-phenylselanylethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6Se
|
1
|
| 1 |
Ki = 656 nM
|
|
|
|
CP0379138
|
1-[3-[4-(3-hydroxypropyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
Ki = 660.69 nM
|
|
|
|
CP0906113
|
(+/-)-11-((1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine
Show/Hide
|
C37H46N6O2
|
1
|
| 1 |
Ki = 661 nM
|
|
|
|
CP0445342
|
N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]thiophene-2-carboxamide
Show/Hide
|
C27H33N3OS
|
1
|
| 1 |
Ki = 663 nM
|
|
|
|
CP0282476
|
1-[3-(Methylsulfonyl)phenyl]-4-propylpiperazine
Show/Hide
|
C14H22N2O2S
|
2
|
| 1 |
Ki = 664 nM
|
|
|
| 2 |
Ki = 1211 nM
|
|
|
|
CP0060505
|
N-[3-[2-[[2-(4-chlorophenyl)cyclopropyl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
|
C29H33ClN2O2
|
1
|
| 1 |
Ki = 667 nM
|
|
|
|
CP0438624
|
4-[(3-chlorophenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6O
|
1
|
| 1 |
Ki = 674 nM
|
|
|
|
CP0443912
|
2-(1H-indol-3-yl)-N-[(5-phenylfuran-2-yl)methyl]ethanamine
Show/Hide
|
C21H20N2O
|
1
|
| 1 |
Ki = 676 nM
|
|
|
|
CP0232092
|
1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C21H32N2O
|
1
|
| 1 |
Ki = 676.08 nM
|
|
|
|
CP0046762
|
(N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine
Show/Hide
|
C11H16N2O
|
1
|
| 1 |
Ki = 679.6 nM
|
|
|
|
CP0534583
|
6-fluoro-N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C25H29FN4O3
|
1
|
| 1 |
Ki = 682 nM
|
|
|
|
CP0399511
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]thieno[2,3-b]pyridine-2-carboxamide
Show/Hide
|
C25H31F3N6OS
|
1
|
| 1 |
Ki = 683 nM
|
|
|
|
CP0376744
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-[3-(4-fluorophenyl)pyridin-2-yl]piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H30FN5O2
|
1
|
| 1 |
Ki = 685 nM
|
|
|
|
CP0451512
|
1-[4-[2-[bis(4-fluorophenyl)methylsulfanyl]ethyl]piperazin-1-yl]propan-2-ol
Show/Hide
|
C22H28F2N2OS
|
1
|
| 1 |
Ki = 693 nM
|
|
|
|
CP0396210
|
N-[[(1R,2R)-2-[(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)methyl]cyclopropyl]methyl]-1H-indole-2-carboxamide
Show/Hide
|
C24H24N4O
|
1
|
| 1 |
Ki = 695 nM
|
|
|
|
CP0426891
|
N-[4-[4-(N-benzylanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C33H37N3O
|
1
|
| 1 |
Ki = 703 nM
|
|
|
|
CP0376254
|
N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-6-methylquinoline-3-carboxamide
Show/Hide
|
C26H32N4O3
|
1
|
| 1 |
Ki = 707 nM
|
|
|
|
CP0438428
|
4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H17ClN4O2S
|
1
|
| 1 |
Ki = 708 nM
|
|
|
|
CP0211080
|
(5aR,11bS)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol
Show/Hide
|
C18H21NO2S
|
1
|
| 1 |
Ki = 710 nM
|
|
|
|
CP0692353
|
5-(4-fluorophenyl)-3-(2-hydroxy-3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H29FN4O4
|
1
|
| 1 |
Ki = 715 nM
|
|
|
|
CP0293888
|
N-[(3S)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C23H26Cl2N4O2
|
2
|
| 1 |
Ki = 715 nM
|
|
|
| 2 |
Ki = 790 nM
|
|
|
|
CP0453915
|
N-[1-[2-(3-fluorophenoxy)ethyl]pyrrolidin-3-yl]thiophene-2-sulfonamide
Show/Hide
|
C16H19FN2O3S2
|
1
|
| 1 |
Ki = 729 nM
|
|
|
|
CP0382741
|
4-(4-methylpiperazin-1-yl)-6-(phenylsulfanylmethyl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H20N6S
|
1
|
| 1 |
Ki = 734 nM
|
|
|
|
CP0402155
|
4-[(3-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6O
|
1
|
| 1 |
Ki = 740 nM
|
|
|
|
CP0159265
|
N-[4-[4-(3-cyanophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C26H28N4OS
|
1
|
| 1 |
Ki = 743 nM
|
|
|
|
CP0057840
|
US8748608, 34
Show/Hide
|
C23H26Cl2N4O2
|
2
|
| 1 |
Ki = 746 nM
|
|
|
| 2 |
Ki = 750 nM
|
|
|
|
CP0537421
|
4-[1-(3,4-dichlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H20Cl2N6O
|
1
|
| 1 |
Ki = 754 nM
|
|
|
|
CP0308847
|
(S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine
Show/Hide
|
C15H23NO2S
|
2
|
| 1 |
Ki = 755 nM
|
|
|
| 2 |
Ki = 3884 nM
|
|
|
|
CP0457522
|
4-[5-[[2-(1H-indol-3-yl)ethylamino]methyl]furan-2-yl]phenol
Show/Hide
|
C21H20N2O2
|
1
|
| 1 |
Ki = 757 nM
|
|
|
|
CP0478827
|
N-[4-[4-(2,4-dichlorophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H27Cl2N3OS
|
1
|
| 1 |
Ki = 757 nM
|
|
|
|
CP0378343
|
2-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)-1-isoindolinone
Show/Hide
|
C22H26ClN3O
|
2
|
| 1 |
Ki = 760 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0381017
|
(+)-R-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine
Show/Hide
|
C37H46N6O2
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0543606
|
2-[4-[3-(4-phenylpiperazin-1-yl)propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
|
C23H30N6
|
1
|
| 1 |
Ki = 770 nM
|
|
|
|
CP0376255
|
N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-6-methoxyquinoline-3-carboxamide
Show/Hide
|
C26H32N4O4
|
1
|
| 1 |
Ki = 774 nM
|
|
|
|
CP0454594
|
N-[4-[(7-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-[3-(4-phenylpiperazin-1-yl)propyl]amino]butyl]benzamide
Show/Hide
|
C34H44N4O2
|
1
|
| 1 |
Ki = 782 nM
|
|
|
|
CP0477977
|
2-[4-[2-hydroxy-3-[4-(4-methoxyphenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]propyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
|
C25H30ClN5O4
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1
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| 1 |
Ki = 782 nM
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CP0852588
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(rac)-4-(4-(1H-Indol-5-yl)-1H-1,2,3-triazol-1-yl)-1-(4-(2-methoxyphenyl)piperazin-1-yl)butan-2-ol
Show/Hide
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C25H30N6O2
|
1
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| 1 |
Ki = 789 nM
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CP0144741
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4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
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C18H17ClN4O2S
|
1
|
| 1 |
Ki = 794 nM
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CP0451468
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(10S,16R)-5-(benzenesulfonyl)-5,13-diazatetracyclo[7.7.0.02,6.010,16]hexadeca-1(9),2(6),3,7-tetraene
Show/Hide
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C20H20N2O2S
|
1
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| 1 |
Ki = 794.33 nM
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CP0410937
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N-[(3R)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
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C23H24Cl2FN3O2
|
1
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| 1 |
Ki = 800 nM
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CP0454988
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2-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]isoindole-1,3-dione
Show/Hide
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C29H29N3O2
|
1
|
| 1 |
Ki = 808 nM
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CP0400252
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1-phenylpiperidine-4-carboxamide
Show/Hide
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C29H41F3N6O
|
1
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| 1 |
Ki = 809 nM
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CP0301336
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N-[[4-[5-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]pentoxy]phenyl]methyl]-N-methylprop-2-yn-1-amine
Show/Hide
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C34H40N4O3S
|
1
|
| 1 |
Ki = 813 nM
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CP0433565
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1-[4-(2-methoxyphenyl)piperazin-1-yl]-4-[4-(4-phenylphenyl)triazol-1-yl]butan-2-ol
Show/Hide
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C29H33N5O2
|
1
|
| 1 |
Ki = 819 nM
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CP0542701
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N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]-6-fluoroquinoline-3-carboxamide
Show/Hide
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C24H25Cl2FN4O2
|
1
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| 1 |
Ki = 827 nM
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CP0438521
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N-[2-[(1S,2R)-2-[[(2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]methyl]cyclopropyl]ethyl]-1H-indole-2-carboxamide
Show/Hide
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C25H31N5O2
|
2
|
| 1 |
Ki = 831 nM
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| 2 |
Ki = 70600 nM
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CP0408800
|
2-butyl-3,4-dihydro-1H-isoquinoline-7-carbonitrile
Show/Hide
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C14H18N2
|
1
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| 1 |
Ki = 832 nM
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CP0484861
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4-fluoro-N-[[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]methyl]benzenesulfonamide
Show/Hide
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C20H24F2N2O3S
|
1
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| 1 |
Ki = 839 nM
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CP0381931
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3-[3-[4-(2-chlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
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C23H26ClFN4O3
|
1
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| 1 |
Ki = 839 nM
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CP0460996
|
N-[4-[4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C32H32ClN3OS
|
1
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| 1 |
Ki = 849 nM
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CP0513011
|
(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) 2-phenylsulfanylacetate
Show/Hide
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C27H27NO2S
|
1
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| 1 |
Ki = 851 nM
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CP0389537
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(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol
Show/Hide
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C19H21NO
|
1
|
| 1 |
Ki = 854 nM
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CP0286303
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6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecin-12-ol
Show/Hide
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C18H21NO
|
1
|
| 1 |
Ki = 857 nM
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CP0580053
|
N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]pyrazine-2-carboxamide
Show/Hide
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C19H25N5O2
|
1
|
| 1 |
Ki = 860 nM
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CP0384570
|
1-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]benzo[cd]indol-2-one
Show/Hide
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C26H30N4O
|
1
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| 1 |
Ki = 867 nM
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CP0460213
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4-(((9H-Fluoren-2-yl)methyl)(methyl)amino)-1-(4-(2,3-dichlorophenyl)piperazin-1-yl)butan-2-ol
Show/Hide
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C29H33Cl2N3O
|
1
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| 1 |
Ki = 869 nM
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CP0380688
|
[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-tert-butylcarbamate
Show/Hide
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C24H30N2O2
|
1
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| 1 |
Ki = 871 nM
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CP0411952
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3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methyl-5-(4-methylphenyl)imidazolidine-2,4-dione;hydrochloride
Show/Hide
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C25H33ClN4O4
|
1
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| 1 |
Ki = 876 nM
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CP0389182
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1-(2,3-dichlorophenyl)-4-[4-[4-(9H-fluoren-2-yl)triazol-1-yl]butyl]piperazine
Show/Hide
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C29H29Cl2N5
|
1
|
| 1 |
Ki = 885 nM
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CP0376256
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N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]quinoline-3-carboxamide
Show/Hide
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C25H29ClN4O3
|
1
|
| 1 |
Ki = 885 nM
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CP0565212
|
N-[(3S)-4-[4-(2-chloro-3-ethylphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C25H30ClFN4O
|
1
|
| 1 |
Ki = 891 nM
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|
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CP0459429
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4-(2-chlorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35ClN4O2
|
1
|
| 1 |
Ki = 896 nM
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CP0364135
|
ethyl N-[3-[4-[4-(naphthalene-2-carbonylamino)butyl]piperazin-1-yl]phenyl]carbamate
Show/Hide
|
C28H34N4O3
|
1
|
| 1 |
Ki = 911 nM
|
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|
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CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 912.01 nM
|
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CP0393633
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1-[3-(4-propylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C20H30N2O
|
1
|
| 1 |
Ki = 912.01 nM
|
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CP0386826
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33F3N6O
|
1
|
| 1 |
Ki = 913 nM
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|
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CP0072089
|
N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-3-carboxamide
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
Ki = 915 nM
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|
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CP0341205
|
N-[3-[2-[[(1S,2R)-2-(2-chlorophenyl)cyclopropyl]-propylamino]ethyl]-3-hydroxycyclobutyl]naphthalene-2-carboxamide
Show/Hide
|
C29H33ClN2O2
|
1
|
| 1 |
Ki = 923 nM
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CP0417076
|
3-[6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]-2lambda6-thia-3-azatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene 2,2-dioxide;hydrochloride
Show/Hide
|
C27H31ClF3N3O2S
|
1
|
| 1 |
Ki = 927 nM
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CP0382164
|
N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-2-carboxamide
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
Ki = 929 nM
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CP0434556
|
2-[4-[3-[4-(4-fluorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C24H26FN5O3
|
1
|
| 1 |
Ki = 931 nM
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CP0476107
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3-[3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-methoxyphenyl)-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C31H37ClN4O4
|
1
|
| 1 |
Ki = 931 nM
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CP0393625
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1-[3-[4-(7-hydroxyheptyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H38N2O2
|
1
|
| 1 |
Ki = 933.25 nM
|
|
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CP0482020
|
N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-5-(hydroxymethyl)imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C26H34F3N7O2
|
1
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| 1 |
Ki = 934 nM
|
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CP0464674
|
3-methyl-6-phenyl-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole
Show/Hide
|
C21H24N2
|
1
|
| 1 |
Ki = 943 nM
|
|
|
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CP0417078
|
1-[6-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]hexyl]benzo[cd]indol-2-one;hydrochloride
Show/Hide
|
C28H31ClF3N3O
|
1
|
| 1 |
Ki = 945 nM
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CP0554601
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2-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]-1,1-dioxo-1,2-benzothiazol-3-one
Show/Hide
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C24H31N3O4S
|
1
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| 1 |
Ki = 950 nM
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CP0548406
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1,1-dioxo-2-[5-(4-pyrimidin-2-ylpiperazin-1-yl)pentyl]-1,2-benzothiazol-3-one
Show/Hide
|
C20H25N5O3S
|
1
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| 1 |
Ki = 954 nM
|
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CP0409215
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(E)-N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
|
C30H34ClN3O
|
1
|
| 1 |
Ki = 963 nM
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CP0852589
|
(rac)-4-(4-(1H-Indol-5-yl)-1H-1,2,3-triazol-1-yl)-1-(4-(2,3-dichlorophenyl)piperazin-1-yl)butan-2-ol
Show/Hide
|
C24H26Cl2N6O
|
1
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| 1 |
Ki = 963 nM
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CP0463475
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4-(4-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H31FN4O2
|
1
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| 1 |
Ki = 963 nM
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CP0471199
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(E)-N-[4-[4-[bis(2-methoxyphenyl)methyl]piperazin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
|
C32H39N3O3
|
1
|
| 1 |
Ki = 972 nM
|
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CP0445423
|
3-((4-(4-chlorophenyl)-4-methylpiperidin-1-yl)methyl)-1H-indole
Show/Hide
|
C21H23ClN2
|
1
|
| 1 |
Ki = 992 nM
|
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CP0073333
|
3-benzenesulfonyl-8-piperazin-1-ylquinoline
Show/Hide
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C19H19N3O2S
|
1
|
| 1 |
Ki = 997 nM
|
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CP0526468
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N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H32ClN3OS
|
1
|
| 1 |
Ki = 1000 nM
|
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CP0381584
|
6-fluoro-N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-2-carboxamide
Show/Hide
|
C25H29FN4O3
|
1
|
| 1 |
Ki = 1000 nM
|
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CP0414404
|
N-methyl-1-(3-naphthalen-1-ylsulfonyl-6,7-dihydrocyclobuta[e]indol-7-yl)methanamine
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
Ki = 1000 nM
|
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CP0402156
|
4-[1-(2-chlorophenoxy)ethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 1001 nM
|
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CP0542757
|
2-N-[6-(4-phenylpiperazin-1-yl)hexyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C19H30N8
|
1
|
| 1 |
Ki = 1009 nM
|
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CP0944914
|
N-(4-((2S,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholino)-3-hydroxybutyl)-1H-indole-2-carboxamide
Show/Hide
|
C23H29N5O3
|
1
|
| 1 |
Ki = 1010 nM
|
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CP0448724
|
4-[4-[2-[4-(3-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C26H31FN4O2S
|
1
|
| 1 |
Ki = 1011 nM
|
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CP0443218
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1-[4-(2-methoxyphenyl)piperazin-1-yl]-4-[4-(2-methoxyphenyl)triazol-1-yl]butan-2-ol
Show/Hide
|
C24H31N5O3
|
1
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| 1 |
Ki = 1020 nM
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CP0478897
|
2-(5-methoxy-1H-indol-3-yl)-N-[(5-quinolin-3-ylfuran-2-yl)methyl]ethanamine
Show/Hide
|
C25H23N3O2
|
1
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| 1 |
Ki = 1025 nM
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CP0341419
|
5,6-dimethoxy-11-methyl-11-aza-tricyclo[13.4.0.0.3,8]nonadeca-1(15),3(8),4,6,16,18-hexaene
Show/Hide
|
C21H27NO2
|
1
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| 1 |
Ki = 1028 nM
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CP0427966
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N-[3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-7-carboxamide
Show/Hide
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C25H30N4O3
|
1
|
| 1 |
Ki = 1030 nM
|
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CP0426410
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3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-methyl-5-phenylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C24H31ClN4O4
|
1
|
| 1 |
Ki = 1033 nM
|
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CP0542994
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2-N-[5-(4-phenylpiperazin-1-yl)pentyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C18H28N8
|
1
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| 1 |
Ki = 1039 nM
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CP0435657
|
2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-fluorophenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H34F2N4O2
|
1
|
| 1 |
Ki = 1047 nM
|
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CP0277135
|
N-[[(1S,2R)-2-[[4-(2,3-dichlorophenyl)piperazin-1-yl]methyl]cyclopropyl]methyl]-4-pyridin-2-ylbenzamide
Show/Hide
|
C27H28Cl2N4O
|
1
|
| 1 |
Ki = 1050 nM
|
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|
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CP0481686
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N-[[1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl]methyl]thiophene-2-sulfonamide
Show/Hide
|
C18H23FN2O3S2
|
1
|
| 1 |
Ki = 1059 nM
|
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CP0402158
|
4-(4-methylpiperazin-1-yl)-6-[(5-methyl-2-propan-2-ylphenoxy)methyl]-1,3,5-triazin-2-amine
Show/Hide
|
C19H28N6O
|
1
|
| 1 |
Ki = 1094 nM
|
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CP0232093
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1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 1096.48 nM
|
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CP0530347
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2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C32H34N4O3
|
1
|
| 1 |
Ki = 1129 nM
|
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CP0379466
|
N-[4-(4-quinazolin-4-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C24H27N7O
|
1
|
| 1 |
Ki = 1133 nM
|
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CP0460995
|
2-[4-[4-(8-oxo-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidin-1-yl]butyl]isoindole-1,3-dione
Show/Hide
|
C30H28N2O3S
|
1
|
| 1 |
Ki = 1149 nM
|
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|
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CP0166592
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H27Cl2N3O
|
1
|
| 1 |
Ki = 1149 nM
|
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|
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CP0913770
|
3-{3-[4-(Diphenylmethyl)piperazin-1-yl]-2-hydroxypropyl}-5,5-dimethylimidazolidine-2,4-dione
Show/Hide
|
C25H32N4O3
|
1
|
| 1 |
Ki = 1152 nM
|
|
|
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CP0384677
|
N-(3-ethylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
Ki = 1159 nM
|
|
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CP0167370
|
4-(2,3-dichlorophenyl)-1-(4-(4-(pyridin-2-yl)benzamido)-transbut-2-enyl)piperazine 1-oxide
Show/Hide
|
C26H26Cl2N4O2
|
1
|
| 1 |
Ki = 1160 nM
|
|
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CP0468994
|
3-(2-methoxyphenyl)-9-[3-[(5-phenyl-1H-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 1162 nM
|
|
|
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CP0476106
|
3-[2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]-5-(4-methoxyphenyl)-5-methylimidazolidine-2,4-dione;hydrochloride
Show/Hide
|
C25H33ClN4O5
|
1
|
| 1 |
Ki = 1165 nM
|
|
|
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CP0554271
|
7-[5-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
|
C22H18ClN3O2S
|
1
|
| 1 |
Ki = 1168 nM
|
|
|
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CP0378647
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1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C22H34N2O2
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1
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| 1 |
Ki = 1174.9 nM
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CP0159262
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5-methyl-4-(1-naphthalen-1-ylsulfonylindol-3-yl)-1H-imidazol-2-amine;hydrochloride
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C22H19ClN4O2S
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1
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| 1 |
Ki = 1175 nM
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CP0519612
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4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N-benzyl-5-methyl-1H-imidazol-2-amine
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C26H24N4O3S
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1
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| 1 |
Ki = 1175 nM
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CP0513759
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2-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]isoindole-1,3-dione
Show/Hide
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C30H33N3O2
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1
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| 1 |
Ki = 1180 nM
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CP0159204
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5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
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C18H17ClN4O3S
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1
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| 1 |
Ki = 1202 nM
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CP0395780
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(+/-)-11-((1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)methoxy)-N-propylnoraporphine
Show/Hide
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C36H44N6O2
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1
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| 1 |
Ki = 1203 nM
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CP0853339
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1-{2-[2-(2,3-Dimethylphenoxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
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C24H36Cl2N2O2
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1
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| 1 |
Ki = 1206 nM
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CP0381741
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1-[4-(2-methoxyphenyl)piperazin-1-yl]-4-(4-phenyltriazol-1-yl)butan-2-ol
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C23H29N5O2
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1
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| 1 |
Ki = 1210 nM
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CP0217150
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IDALOPIRDINE
Show/Hide
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C20H19F5N2O
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1
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| 1 |
Ki = 1215 nM
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CP0460397
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4-[4-[2-(4-phenylpiperazin-1-yl)ethyl]piperidin-1-yl]sulfonylisoquinoline
Show/Hide
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C26H32N4O2S
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1
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| 1 |
Ki = 1218 nM
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CP0260574
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CHEMBL3265065
Show/Hide
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C29H33ClN2O2
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1
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| 1 |
Ki = 1220 nM
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CP0059583
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1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one
Show/Hide
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C19H23N5O3S
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1
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| 1 |
Ki = 1224 nM
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CP0431612
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4-[(4-chloro-3-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C16H21ClN6O
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1
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| 1 |
Ki = 1224 nM
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CP0438423
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2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine;hydrochloride
Show/Hide
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C22H23ClN4O3S
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1
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| 1 |
Ki = 1230 nM
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CP0382742
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4-[(2,4-dichlorophenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
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C15H18Cl2N6O
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1
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| 1 |
Ki = 1234 nM
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CP0470500
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5-[4-[2-(4-phenylpiperazin-1-yl)ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
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C26H32N4O2S
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1
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| 1 |
Ki = 1237 nM
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CP0460991
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(E)-N-[4-(3,4-dihydro-1H-isoquinolin-2-yl)butyl]-3-phenylprop-2-enamide
Show/Hide
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C22H26N2O
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1
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| 1 |
Ki = 1272 nM
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CP0476109
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2-[4-[3-[4-(4-chlorophenyl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-2-hydroxypropyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
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C24H27Cl2N5O3
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1
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| 1 |
Ki = 1285 nM
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CP0541083
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2-[6-(4-pyridin-2-ylpiperazin-1-yl)hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C27H30N4O2
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1
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| 1 |
Ki = 1302 nM
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CP0400250
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N-[4-[4-(3,5-ditert-butylphenyl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C30H43N5O
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1
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| 1 |
Ki = 1303 nM
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CP0435403
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4-(5-methoxy-1-naphthalen-1-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-amine;hydrochloride
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C23H21ClN4O3S
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1
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| 1 |
Ki = 1318 nM
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CP0426889
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N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]naphthalene-2-carboxamide
Show/Hide
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C32H33N3O
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1
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| 1 |
Ki = 1324 nM
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CP0382745
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4-(4-methylpiperazin-1-yl)-6-(phenoxymethyl)-1,3,5-triazin-2-amine
Show/Hide
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C15H20N6O
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1
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| 1 |
Ki = 1348 nM
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CP0272134
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(4-fluorophenyl)-[1-[(3S,4S)-1-[(4-fluorophenyl)methyl]-3-hydroxypiperidin-4-yl]piperidin-4-yl]methanone
Show/Hide
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C24H28F2N2O2
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1
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| 1 |
Ki = 1350 nM
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CP0421349
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2-(5-methoxy-1H-indol-3-yl)-N-[[5-(4-methoxyphenyl)furan-2-yl]methyl]ethanamine
Show/Hide
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C23H24N2O3
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1
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| 1 |
Ki = 1365 nM
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CP0376748
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6-[4-[2-(4-cyanophenyl)-4-fluorophenyl]piperazin-1-yl]-N-[(4-cyanophenyl)methyl]hexanamide
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C31H32FN5O
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1
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| 1 |
Ki = 1385 nM
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CP0545011
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2-[[4-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]phenyl]methyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Show/Hide
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C24H24ClN5O
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1
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| 1 |
Ki = 1390 nM
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CP0277602
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2-methoxy-7-methyl-6,7,8,9,10,15-hexahydro-5H-dibenzo[d,g]azacycloundecene
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C20H25NO
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1
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| 1 |
Ki = 1396 nM
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CP0919396
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1-((5-Methoxy-1H-indol-3-yl)methyl)-4-phenylpiperidin-4-ol oxalate
Show/Hide
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C23H26N2O6
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1
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| 1 |
Ki = 1396 nM
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CP0560050
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(2R)-1-[4-(2,3-dichlorophenyl)piperazin-1-yl]propan-2-ol
Show/Hide
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C13H18Cl2N2O
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1
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| 1 |
Ki = 1400 nM
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CP0530224
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6-[3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylquinoline
Show/Hide
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C22H19N3O2S
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1
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| 1 |
Ki = 1410 nM
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CP0693927
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SID50106425
Show/Hide
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C16H26BrNO
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1
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| 1 |
Ki = 1430 nM
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CP0396213
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N-[[(1R,2R)-2-[(7-cyano-3,4-dihydro-1H-isoquinolin-2-yl)methyl]cyclopropyl]methyl]quinoline-4-carboxamide
Show/Hide
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C25H24N4O
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1
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| 1 |
Ki = 1440 nM
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CP0417011
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N-[4-[4-(6-ethyl-1,3-benzodioxol-5-yl)piperazin-1-yl]-3-hydroxybutyl]-1-benzofuran-2-carboxamide
Show/Hide
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C26H31N3O5
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1
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| 1 |
Ki = 1440 nM
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CP0513107
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N-[4-[4-(2-tert-butylquinazolin-4-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C28H35N7O
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1
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| 1 |
Ki = 1452 nM
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CP0401522
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5,6,8,9,10,14c-Hexahydroindolo[3',2':3,4,]pyrido[2,1-a]isoquinoline
Show/Hide
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C19H18N2
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1
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| 1 |
Ki = 1476 nM
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CP0296558
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[1-[(3S,4S)-1-[(4-fluorophenyl)methyl]-3-hydroxypiperidin-4-yl]piperidin-4-yl]-(4-methoxyphenyl)methanone
Show/Hide
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C25H31FN2O3
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1
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| 1 |
Ki = 1489 nM
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CP0384371
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N-(3-methylphenyl)-3-(4-pyrimidin-2-ylpiperazin-1-yl)propanamide
Show/Hide
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C18H23N5O
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2
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| 1 |
Ki = 1490 nM
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| 2 |
Ki = 1850 nM
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CP0573200
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2-[4-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C24H32N6O
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1
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| 1 |
Ki = 1500 nM
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CP0537415
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4-(4-methylpiperazin-1-yl)-6-(1-phenoxypropyl)-1,3,5-triazin-2-amine
Show/Hide
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C17H24N6O
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1
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| 1 |
Ki = 1506 nM
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CP0386829
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N-[4-[4-[2-tert-butyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]-4-phenylcyclohexane-1-carboxamide
Show/Hide
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C30H42F3N5O
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1
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| 1 |
Ki = 1510 nM
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CP0037328
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(6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium
Show/Hide
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C17H17NO2
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1
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| 1 |
Ki = 1520 nM
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CP0566754
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3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-methyl-1-phenylurea
Show/Hide
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C23H32N4O2
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1
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| 1 |
Ki = 1549 nM
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CP0067696
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(1R,3S)-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1H-2-benzopyran-5,6-diol;hydrochloride
Show/Hide
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C20H27NO3
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1
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| 1 |
Ki = 1550 nM
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CP0095889
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N-[4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
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C26H28F3N3O
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1
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| 1 |
Ki = 1553 nM
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CP0482018
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N-[4-(4-quinolin-2-ylpiperazin-1-yl)butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C25H28N6O
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1
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| 1 |
Ki = 1563 nM
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CP0454989
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N-[4-[4-(N-benzylanilino)piperidin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Show/Hide
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C31H35N3OS
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1
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| 1 |
Ki = 1570 nM
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CP0483103
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2-[4-[5-[3-[3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecan-9-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]phenyl]-1,3-oxazole
Show/Hide
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C31H38N6O2S
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1
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| 1 |
Ki = 1574 nM
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CP0552643
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4-[1-(benzenesulfonyl)indol-3-yl]-5-ethyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
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C19H19ClN4O2S
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1
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| 1 |
Ki = 1585 nM
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CP0443872
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N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1-benzofuran-2-carboxamide
Show/Hide
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C26H32ClN3O4
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1
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| 1 |
Ki = 1620 nM
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CP0046420
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CAS_3853
Show/Hide
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C18H19ClN4
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1
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| 1 |
Ki = 1621.81 nM
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CP0424446
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4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
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C20H21ClN4O3S
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1
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| 1 |
Ki = 1622 nM
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CP0423148
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4-(4-chlorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35ClN4O2
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1
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| 1 |
Ki = 1651 nM
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CP0476108
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2-[4-[2-hydroxy-3-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)propyl]piperazin-1-yl]benzonitrile;hydrochloride
Show/Hide
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C24H28ClN5O3
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1
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| 1 |
Ki = 1690 nM
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CP0429032
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[(1S,2R,5R,6R,7R)-3-benzyl-7-(diethylamino)-2-phenyl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
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C24H32N2O
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1
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| 1 |
Ki = 1700 nM
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CP0462367
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5-(4-fluorophenyl)-3-[3-[4-(2-fluorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methylimidazolidine-2,4-dione
Show/Hide
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C23H26F2N4O3
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1
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| 1 |
Ki = 1709 nM
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CP0035276
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1-(4-fluorophenyl)-4-(4-hydroxy-5-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-5-yl)butan-1-one
Show/Hide
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C21H22FNO2
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1
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| 1 |
Ki = 1724 nM
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CP0443917
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2-(5-methoxy-1H-indol-3-yl)-N-[[5-(1H-pyrazol-4-yl)furan-2-yl]methyl]ethanamine
Show/Hide
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C19H20N4O2
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1
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| 1 |
Ki = 1730 nM
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CP0425631
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5-[(5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine
Show/Hide
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C13H21N3O
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1
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| 1 |
Ki = 1740 nM
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CP0459430
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2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C33H40N4O4
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1
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| 1 |
Ki = 1802 nM
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CP0404556
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3-[3-[4-(2,5-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
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C25H31FN4O3
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1
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| 1 |
Ki = 1814 nM
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CP0417574
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5-[4-[2-[4-(3-fluorophenyl)piperazin-1-yl]ethyl]piperidin-1-yl]sulfonylquinoline
Show/Hide
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C26H31FN4O2S
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1
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| 1 |
Ki = 1821 nM
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CP0519605
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N-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
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C26H31N3O2S
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1
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| 1 |
Ki = 1832 nM
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CP0421835
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5-bromo-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
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C12H10BrN3
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1
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| 1 |
Ki = 1862 nM
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CP0513108
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N-[4-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
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C25H27ClN6O
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1
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| 1 |
Ki = 1883 nM
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CP0569187
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4-(3-chlorophenyl)-N-[6-(3-oxo-[1,2,4]triazolo[4,3-a]pyridin-2-yl)hexyl]piperazine-1-carboxamide
Show/Hide
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C23H29ClN6O2
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1
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| 1 |
Ki = 1940 nM
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CP0376741
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N-[(4-cyanophenyl)methyl]-3-[2-[4-[2-(4-fluorophenyl)pyridin-3-yl]piperazin-1-yl]ethoxy]propanamide
Show/Hide
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C28H30FN5O2
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1
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| 1 |
Ki = 1959 nM
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CP0397958
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3-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
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C23H25Cl2FN4O3
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1
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| 1 |
Ki = 1976 nM
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CP0384283
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4-(4-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35FN4O2
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1
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| 1 |
Ki = 1977 nM
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CP0414871
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1-[3-(benzenesulfonyl)-6,7-dihydrocyclobuta[e]indol-7-yl]-N-methylmethanamine
Show/Hide
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C18H18N2O2S
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1
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| 1 |
Ki = 1995.26 nM
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CP0449020
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N-[[4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-yl]methyl]acetamide
Show/Hide
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C23H26ClN3O
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1
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| 1 |
Ki = 2000 nM
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CP0502925
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[(1S,2R,5R,6R,7R)-3-benzyl-2-(4-bromophenyl)-7-(diethylamino)-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
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C24H31BrN2O
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1
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| 1 |
Ki = 2000 nM
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CP0509754
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[(1S,2R,5R,6R,7R)-3-benzyl-2-phenyl-7-piperidin-1-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
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C25H32N2O
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1
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| 1 |
Ki = 2000 nM
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CP0426136
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(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) N-naphthalen-1-ylcarbamate
Show/Hide
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C30H28N2O2
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1
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| 1 |
Ki = 2005 nM
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CP0075581
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N-[4-[4-(3,5-dichlorophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
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C25H27Cl2N3OS
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1
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| 1 |
Ki = 2049 nM
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CP0206600
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4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-(9H-fluoren-2-ylmethyl)-3-fluoro-N-methylbutan-1-amine
Show/Hide
|
C29H32Cl2FN3
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1
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| 1 |
Ki = 2060 nM
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CP0908362
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endo-8-(1H-Indol-3-ylmethyl)-3-(2-methoxyphenyl)-8-azabicyclo[3.2.1]octan-3-ol
Show/Hide
|
C23H26N2O2
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1
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| 1 |
Ki = 2070 nM
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CP0482239
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4-(((9H-Fluoren-2-yl)methyl)amino)-1-(4-(2,3-dichlorophenyl)piperazin-1-yl)butan-2-ol
Show/Hide
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C28H31Cl2N3O
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1
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| 1 |
Ki = 2090 nM
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CP0569926
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2-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]piperazin-1-yl]pyridine-3-carbonitrile
Show/Hide
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C23H27N5O2
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1
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| 1 |
Ki = 2100 nM
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CP0577590
|
phenyl-[4-[3-(4-phenylpiperazin-1-yl)propyl]piperazin-1-yl]methanone
Show/Hide
|
C24H32N4O
|
1
|
| 1 |
Ki = 2100 nM
|
|
|
|
CP0456678
|
5-[5-[3-[(1S,5R)-1-[2-fluoro-4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hexan-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
Show/Hide
|
C22H23F4N5OS
|
1
|
| 1 |
Ki = 2110 nM
|
|
|
|
CP0492204
|
3-(2-methoxyphenyl)-9-[3-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H39N5O2S
|
1
|
| 1 |
Ki = 2112 nM
|
|
|
|
CP0853987
|
3-{2-Hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}-5,5-dimethylimidazolidine-2,4-dione
Show/Hide
|
C19H28N4O4
|
1
|
| 1 |
Ki = 2130 nM
|
|
|
|
CP0519608
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-N-(2-phenylethyl)-1H-imidazol-2-amine
Show/Hide
|
C27H26N4O3S
|
1
|
| 1 |
Ki = 2138 nM
|
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|
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CP0532000
|
N-cyclohexyl-2-[4-[3-(5-fluoro-1H-indol-3-yl)propyl]piperazin-1-yl]-N-phenylacetamide
Show/Hide
|
C29H37FN4O
|
1
|
| 1 |
Ki = 2161.35 nM
|
|
|
|
CP0869680
|
2-(4-(4-(2,3-difluorophenyl)piperazin-1-yl)butyl)isoindoline-1,3-dione
Show/Hide
|
C22H23F2N3O2
|
1
|
| 1 |
Ki = 2163.1 nM
|
|
|
|
CP0426667
|
1-[[(2R)-3,3-diphenyl-1,4-dioxan-2-yl]methyl]-4-(2-methoxyphenyl)piperazine
Show/Hide
|
C28H32N2O3
|
1
|
| 1 |
Ki = 2187.76 nM
|
|
|
|
CP0426137
|
[(6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl] N-benzylcarbamate
Show/Hide
|
C27H28N2O2
|
1
|
| 1 |
Ki = 2200 nM
|
|
|
|
CP0434555
|
3-[3-[4-(3,4-dimethylphenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C25H31FN4O3
|
1
|
| 1 |
Ki = 2261 nM
|
|
|
|
CP0445344
|
2-(4-(4-(2-methoxyphenylamino)piperidin-1-yl)butyl)isoindoline-1,3-dione
Show/Hide
|
C24H29N3O3
|
1
|
| 1 |
Ki = 2288 nM
|
|
|
|
CP0460520
|
N-[[(1R,2R)-2-[[4-(3-cyanophenyl)piperazin-1-yl]methyl]cyclopropyl]methyl]quinoline-4-carboxamide
Show/Hide
|
C26H27N5O
|
1
|
| 1 |
Ki = 2290 nM
|
|
|
|
CP0052067
|
2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine
Show/Hide
|
C18H19ClN4
|
2
|
| 1 |
Ki = 2300 nM
|
|
|
| 2 |
Ki = 47000 nM
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|
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CP0440942
|
5-[(2S,5S)-5-methylmorpholin-2-yl]pyridin-2-amine
Show/Hide
|
C10H15N3O
|
1
|
| 1 |
Ki = 2340 nM
|
|
|
|
CP0566208
|
4-(5-methoxy-1-naphthalen-2-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C23H21ClN4O3S
|
1
|
| 1 |
Ki = 2344 nM
|
|
|
|
CP0423146
|
2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H36N4O2
|
1
|
| 1 |
Ki = 2349 nM
|
|
|
|
CP0382744
|
4-[(2-chlorophenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6O
|
1
|
| 1 |
Ki = 2362 nM
|
|
|
|
CP0449019
|
(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-yl)methanol
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
Ki = 2370 nM
|
|
|
|
CP0384667
|
N-(3-methylphenyl)-2-(4-pyrimidin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C17H21N5O
|
2
|
| 1 |
Ki = 2420 nM
|
|
|
| 2 |
Ki = 6400 nM
|
|
|
|
CP0382644
|
3-[2-[4-(2-phenylphenyl)piperazin-1-yl]ethoxy]-N-(pyridin-4-ylmethyl)propanamide
Show/Hide
|
C27H32N4O2
|
1
|
| 1 |
Ki = 2450 nM
|
|
|
|
CP0414817
|
N-[(3S)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C23H24Cl2FN3O2
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0382704
|
2-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]isoindole-1,3-dione
Show/Hide
|
C26H30N2O5
|
1
|
| 1 |
Ki = 2510 nM
|
|
|
|
CP0398689
|
N-methyl-1-(9-naphthalen-1-ylsulfonyl-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl)methanamine
Show/Hide
|
C22H20N2O2S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0864137
|
1-(4-(4-([1,10-Biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)-butyl)-4-(2,3-dichlorophenyl)piperazine
Show/Hide
|
C28H29Cl2N5
|
1
|
| 1 |
Ki = 2590 nM
|
|
|
|
CP0891093
|
7-(4-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one oxalate
Show/Hide
|
C26H31ClN2O7
|
1
|
| 1 |
Ki = 2604 nM
|
|
|
|
CP0548208
|
7-[3-[3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecan-9-yl]propoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C28H37N3O3
|
1
|
| 1 |
Ki = 2630 nM
|
|
|
|
CP0422924
|
7-[4-[(2R,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H30N4O3
|
1
|
| 1 |
Ki = 2660 nM
|
|
|
|
CP0525594
|
3-[2-[4-(2-phenylpyridin-3-yl)piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C28H31F3N4O2
|
1
|
| 1 |
Ki = 2766 nM
|
|
|
|
CP0468996
|
N-[4-[3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecan-9-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C31H39N3O2S
|
1
|
| 1 |
Ki = 2766 nM
|
|
|
|
CP0466071
|
(6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl) N-tert-butylcarbamate
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
Ki = 2800 nM
|
|
|
|
CP0055980
|
N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-2-methoxy-5-methylbenzamide
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
Ki = 2850 nM
|
|
|
|
CP0372344
|
1-((1H-indol-3-yl)methyl)-4-(4-chlorobenzyl)piperidin-4-ol
Show/Hide
|
C21H23ClN2O
|
1
|
| 1 |
Ki = 2890 nM
|
|
|
|
CP0294037
|
N-[3-fluoro-4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C29H32FN3O2
|
1
|
| 1 |
Ki = 2890 nM
|
|
|
|
CP0472031
|
5-(4-fluorophenyl)-3-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
Ki = 2906 nM
|
|
|
|
CP0431614
|
4-[(4-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6O
|
1
|
| 1 |
Ki = 2916 nM
|
|
|
|
CP0431323
|
[(12S)-11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaen-12-yl]methanol
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 2923 nM
|
|
|
|
CP0417454
|
3-[(3-chlorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
Show/Hide
|
C20H24ClN5
|
1
|
| 1 |
Ki = 2941 nM
|
|
|
|
CP0421837
|
3-(3-ethylimidazol-4-yl)-7-fluoro-5-iodo-1H-indole
Show/Hide
|
C13H11FIN3
|
1
|
| 1 |
Ki = 3020 nM
|
|
|
|
CP0544200
|
4-N-[2-(2,3-dichlorophenyl)ethyl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H21Cl2N7
|
1
|
| 1 |
Ki = 3077 nM
|
|
|
|
CP0519614
|
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-1H-imidazo[1,2-a]pyridin-4-ium;bromide
Show/Hide
|
C23H20BrN3O3S
|
1
|
| 1 |
Ki = 3162 nM
|
|
|
|
CP0544198
|
6-[4-(2,3-dichlorophenyl)piperazin-1-yl]-2-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C23H24Cl2N8
|
1
|
| 1 |
Ki = 3207 nM
|
|
|
|
CP0573032
|
3-(2-methoxyphenyl)-9-[3-[[4-methyl-5-(4-thiophen-3-ylphenyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C32H39N5OS2
|
1
|
| 1 |
Ki = 3250 nM
|
|
|
|
CP0430226
|
4-[5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)indol-1-yl]sulfonylisoquinoline
Show/Hide
|
C23H21N3O3S
|
1
|
| 1 |
Ki = 3319 nM
|
|
|
|
CP0384672
|
N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C18H22N4O
|
2
|
| 1 |
Ki = 3320 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0095894
|
N-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28ClN3O
|
1
|
| 1 |
Ki = 3323 nM
|
|
|
|
CP0864861
|
3-{2-Hydroxy-3-[4-(2-cyanophenyl)piperazin-1-yl]propyl}-5,5-dimethylimidazolidine-2,4-dione
Show/Hide
|
C19H25N5O3
|
1
|
| 1 |
Ki = 3429 nM
|
|
|
|
CP0389653
|
3-[(3-fluorophenyl)methyl]-7-piperazin-1-yl-2-propan-2-ylimidazo[4,5-b]pyridine
Show/Hide
|
C20H24FN5
|
1
|
| 1 |
Ki = 3436 nM
|
|
|
|
CP0476734
|
N-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
Ki = 3449 nM
|
|
|
|
CP0376746
|
3-[2-[4-[2-(4-fluorophenyl)pyridin-3-yl]piperazin-1-yl]ethoxy]-N-[[4-(trifluoromethyl)phenyl]methyl]propanamide
Show/Hide
|
C28H30F4N4O2
|
1
|
| 1 |
Ki = 3460 nM
|
|
|
|
CP0073332
|
2-ethyl-3-[(3-fluorophenyl)methyl]-7-piperazin-1-ylimidazo[4,5-b]pyridine
Show/Hide
|
C19H22FN5
|
1
|
| 1 |
Ki = 3482 nM
|
|
|
|
CP0464229
|
3-methyl-N-(3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
Ki = 3500 nM
|
|
|
|
CP0043442
|
Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Show/Hide
|
C23H25Cl2N3OS
|
1
|
| 1 |
Ki = 3600 nM
|
|
|
|
CP0493761
|
N-[4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 3631 nM
|
|
|
|
CP0386821
|
N-[4-[4-[6-methyl-2-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C22H26F3N7O
|
1
|
| 1 |
Ki = 3646 nM
|
|
|
|
CP0574554
|
4-(dimethylamino)-N-[4-[3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecan-9-yl]butyl]benzamide
Show/Hide
|
C29H42N4O2
|
1
|
| 1 |
Ki = 3762 nM
|
|
|
|
CP0472845
|
1-[3-(4-benzylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
Ki = 3801.89 nM
|
|
|
|
CP0476616
|
5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1-(2,2-difluoroethyl)-4-methylimidazol-2-amine
Show/Hide
|
C21H20F2N4O3S
|
1
|
| 1 |
Ki = 3802 nM
|
|
|
|
CP0438518
|
N-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C27H33N3O4
|
1
|
| 1 |
Ki = 3860 nM
|
|
|
|
CP0458244
|
[(1R,2S,5R,6R,7R)-3-benzyl-7-(diethylamino)-2-methyl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C19H30N2O
|
1
|
| 1 |
Ki = 3900 nM
|
|
|
|
CP0542759
|
4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(2-methoxyanilino)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C22H26N8O
|
1
|
| 1 |
Ki = 3907 nM
|
|
|
|
CP0144745
|
4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N-(2,2-difluoroethyl)-5-methyl-1H-imidazol-2-amine
Show/Hide
|
C21H20F2N4O3S
|
1
|
| 1 |
Ki = 3981 nM
|
|
|
|
CP0435404
|
5-[1-(benzenesulfonyl)indol-4-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C17H15ClN4O2S
|
1
|
| 1 |
Ki = 3981 nM
|
|
|
|
CP0657734
|
(5aS,11bR)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol hydrochloride
Show/Hide
|
C18H22ClNO2S
|
1
|
| 1 |
Ki = 4020 nM
|
|
|
|
CP0852964
|
3-{3-[4-(4-Chlorophenoxy)piperidin-1-yl]-2-hydroxypropyl}-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H27ClFN3O4
|
1
|
| 1 |
Ki = 4116 nM
|
|
|
|
CP0382743
|
4-[(2-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H22N6O
|
1
|
| 1 |
Ki = 4247 nM
|
|
|
|
CP0471920
|
(4aR,10bR)-2,3,4,4a,5,10b-hexahydrochromeno[4,3-b][1,4]oxazin-9-ol
Show/Hide
|
C11H13NO3
|
1
|
| 1 |
Ki = 4250 nM
|
|
|
|
CP0434552
|
3-[3-[4-(4-chlorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H26ClFN4O3
|
1
|
| 1 |
Ki = 4255 nM
|
|
|
|
CP0329850
|
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-fluorobutyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C28H28Cl2FN3O
|
1
|
| 1 |
Ki = 4260 nM
|
|
|
|
CP0372387
|
1-((1H-indol-3-yl)methyl)-3-(4-chlorophenyl)piperidin-3-ol
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
Ki = 4265 nM
|
|
|
|
CP0919252
|
(6aR,S)-N-n-Propylnoraporphin-11-ylbenzylcarbamate
Show/Hide
|
C27H28N2O2
|
1
|
| 1 |
Ki = 4300 nM
|
|
|
|
CP0445867
|
N-[(4-cyanophenyl)methyl]-3-[2-[4-(2-phenylpyridin-3-yl)piperazin-1-yl]ethoxy]propanamide
Show/Hide
|
C28H31N5O2
|
1
|
| 1 |
Ki = 4346 nM
|
|
|
|
CP0864860
|
5-(4-Fluorophenyl)-3-[2-hydroxy-3-(4-phenoxypiperidin-1-yl)-propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H28FN3O4
|
1
|
| 1 |
Ki = 4353 nM
|
|
|
|
CP0431613
|
4-[(4-chloro-2-methylphenoxy)methyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C16H21ClN6O
|
1
|
| 1 |
Ki = 4369 nM
|
|
|
|
CP0568664
|
4-N-[2-(1H-indol-3-yl)ethyl]-2-N-[2-(2-methoxyphenoxy)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C22H25N7O2
|
1
|
| 1 |
Ki = 4402 nM
|
|
|
|
CP0575067
|
2-N-[2-(2,3-dichlorophenoxy)ethyl]-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H21Cl2N7O
|
1
|
| 1 |
Ki = 4402 nM
|
|
|
|
CP0400347
|
2,6,7,9,10,14b-Hexahydroindolo[3',4':3,4,5]azepino[2,1-a]-isoquinoline
Show/Hide
|
C19H18N2
|
1
|
| 1 |
Ki = 4458 nM
|
|
|
|
CP0393627
|
1-[3-(4-methylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C18H26N2O
|
1
|
| 1 |
Ki = 4466.84 nM
|
|
|
|
CP0482017
|
N-[4-[4-(6-tert-butyl-2-methylpyrimidin-4-yl)piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C25H35N7O
|
1
|
| 1 |
Ki = 4604 nM
|
|
|
|
CP0460993
|
N-[4-[4-(N-benzoyl-2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C34H37N3O3
|
1
|
| 1 |
Ki = 4620 nM
|
|
|
|
CP0087918
|
(R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
Show/Hide
|
C16H17NO2
|
1
|
| 1 |
Ki = 4670 nM
|
|
|
|
CP0489689
|
N-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
Ki = 4753 nM
|
|
|
|
CP0413064
|
3-(3-ethylimidazol-4-yl)-5-iodo-1H-indole
Show/Hide
|
C13H12IN3
|
2
|
| 1 |
Ki = 4847 nM
|
|
|
| 2 |
Ki = 4898 nM
|
|
|
|
CP0396167
|
3-piperazin-1-ylbenzonitrile
Show/Hide
|
C11H13N3
|
1
|
| 1 |
Ki = 4890 nM
|
|
|
|
CP0426893
|
N-[4-(2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaen-5-yl)butyl]-1-benzothiophene-2-carboxamide
Show/Hide
|
C30H31N3OS
|
1
|
| 1 |
Ki = 4925 nM
|
|
|
|
CP0853338
|
1-[3-(Mesityloxy)propyl]-4-(4-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C23H34Cl2N2O2
|
1
|
| 1 |
Ki = 4963 nM
|
|
|
|
CP0482019
|
N-[4-[4-[7-(trifluoromethyl)quinolin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C26H27F3N6O
|
1
|
| 1 |
Ki = 4983 nM
|
|
|
|
CP0409126
|
[(1R,2S,5S,6S,7S)-3-benzyl-2-(4-bromophenyl)-7-(diethylamino)-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C24H31BrN2O
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0544199
|
2-N-[2-(2,3-dichloroanilino)ethyl]-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H22Cl2N8
|
1
|
| 1 |
Ki = 5003 nM
|
|
|
|
CP0071763
|
N-[4-[4-(2-hydroxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H29N3O2
|
1
|
| 1 |
Ki = 5031 nM
|
|
|
|
CP0447952
|
(10R)-10-(methylamino)-2-oxo-1,3-diazatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-6-carbonitrile
Show/Hide
|
C12H12N4O
|
1
|
| 1 |
Ki = 5120 nM
|
|
|
|
CP0411642
|
1-[3-(4-butylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C20H31N3O
|
1
|
| 1 |
Ki = 5128.61 nM
|
|
|
|
CP0476602
|
4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1,3-thiazol-2-amine
Show/Hide
|
C18H15N3O2S2
|
1
|
| 1 |
Ki = 5129 nM
|
|
|
|
CP0200768
|
N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
Show/Hide
|
C28H30N4O
|
1
|
| 1 |
Ki = 5160 nM
|
|
|
|
CP0416956
|
3-(2-ethoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H39N5OS
|
1
|
| 1 |
Ki = 5165 nM
|
|
|
|
CP0381934
|
5-(4-fluorophenyl)-3-[2-hydroxy-3-[4-(3-methoxyphenyl)piperazin-1-yl]propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H29FN4O4
|
1
|
| 1 |
Ki = 5187 nM
|
|
|
|
CP0382707
|
N-[4-[(2R,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]butyl]-1H-indole-2-carboxamide
Show/Hide
|
C23H29N5O2
|
1
|
| 1 |
Ki = 5220 nM
|
|
|
|
CP0900154
|
5-(4-Fluorophenyl)-3-(2-hydroxy-3-{4-[(naphthalen-1-yl)-methyl]piperazin-1-yl}propyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C28H31FN4O3
|
1
|
| 1 |
Ki = 5233 nM
|
|
|
|
CP0521240
|
N-[4-[1-(benzenesulfonyl)indol-6-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki = 5248 nM
|
|
|
|
CP0460212
|
4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-N-(9H-fluoren-2-ylmethyl)-3-fluorobutan-1-amine
Show/Hide
|
C28H30Cl2FN3
|
1
|
| 1 |
Ki = 5270 nM
|
|
|
|
CP0464320
|
1-((1H-indol-3-yl)methyl)-4-(4-hydroxyphenyl)piperidin-4-ol
Show/Hide
|
C20H22N2O2
|
1
|
| 1 |
Ki = 5360 nM
|
|
|
|
CP0576951
|
[4-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]piperazin-1-yl]-phenylmethanone
Show/Hide
|
C25H34N4O2
|
1
|
| 1 |
Ki = 5500 nM
|
|
|
|
CP0519118
|
N-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]-1,3-benzothiazole-2-carboxamide
Show/Hide
|
C26H31N3O4S
|
1
|
| 1 |
Ki = 5510 nM
|
|
|
|
CP0757055
|
3-(1-methyl-1H-imidazol-5-yl)-1H-indole-5-carboxamide
Show/Hide
|
C13H12N4O
|
1
|
| 1 |
Ki = 5561 nM
|
|
|
|
CP0889346
|
N-(Benzothiazol-2-yl)-5-(4-(2,4-dichlorophenyl)piperazin-1-yl)pentanamide hydrochloride
Show/Hide
|
C22H25Cl3N4OS
|
1
|
| 1 |
Ki = 5586 nM
|
|
|
|
CP0381937
|
5-(4-fluorophenyl)-3-[3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H26F2N4O3
|
1
|
| 1 |
Ki = 5641 nM
|
|
|
|
CP0416960
|
9-[3-[(4-ethyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H39N5OS
|
1
|
| 1 |
Ki = 5650 nM
|
|
|
|
CP0393626
|
1-[3-[4-(2-phenylethyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H31N3O
|
1
|
| 1 |
Ki = 5754.4 nM
|
|
|
|
CP0900155
|
5-(4-Fluorophenyl)-3-[2-hydroxy-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-5-methylimidazolidine-2,4-dione
Show/Hide
|
C22H24FN3O3
|
1
|
| 1 |
Ki = 5848 nM
|
|
|
|
CP0922740
|
N-(4-((4aS,10bS)-9-hydroxy-2,3,4a,5-tetrahydrochromeno[4,3-b][1,4]oxazin-4(10bH)-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
Ki = 5880 nM
|
|
|
|
CP0416955
|
3-(2-methoxyphenyl)-9-[3-[(5-phenyl-1H-imidazol-2-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H36N4OS
|
1
|
| 1 |
Ki = 5891 nM
|
|
|
|
CP0417452
|
3-[(3-chlorophenyl)methyl]-2-ethyl-7-piperazin-1-ylimidazo[4,5-b]pyridine
Show/Hide
|
C19H22ClN5
|
1
|
| 1 |
Ki = 6100 nM
|
|
|
|
CP0098320
|
2-(2-methoxyphenyl)-8-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,8-diazaspiro[4.5]decane
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 6168 nM
|
|
|
|
CP0382712
|
7-[4-[(4aR,10bR)-9-hydroxy-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-4-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C24H28N2O5
|
1
|
| 1 |
Ki = 6260 nM
|
|
|
|
CP0399599
|
2-[(4S,5R)-9-(benzenesulfonyl)-5-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 6309.57 nM
|
|
|
|
CP0547879
|
2-(2-methoxyphenyl)-7-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,7-diazaspiro[4.4]nonane
Show/Hide
|
C26H33N5OS
|
1
|
| 1 |
Ki = 6370 nM
|
|
|
|
CP0416957
|
3-[2-(2-fluoroethoxy)phenyl]-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H38FN5OS
|
1
|
| 1 |
Ki = 6379 nM
|
|
|
|
CP0382711
|
N-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]-9H-fluorene-2-carboxamide
Show/Hide
|
C32H36N2O4
|
1
|
| 1 |
Ki = 6710 nM
|
|
|
|
CP0392641
|
3-[3-[4-(2,4-difluorophenyl)piperazin-1-yl]-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C23H25F3N4O3
|
1
|
| 1 |
Ki = 6790 nM
|
|
|
|
CP0423854
|
[(1R,2S,5S,6S,7S)-3-benzyl-2-phenyl-7-piperidin-1-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C25H32N2O
|
1
|
| 1 |
Ki = 7000 nM
|
|
|
|
CP0440884
|
5-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-1H-imidazol-2-amine;hydrochloride
Show/Hide
|
C18H16ClFN4O3S
|
1
|
| 1 |
Ki = 7079 nM
|
|
|
|
CP0344919
|
3-(3-ethylimidazol-4-yl)-4-fluoro-5-iodo-1H-indole
Show/Hide
|
C13H11FIN3
|
1
|
| 1 |
Ki = 7080 nM
|
|
|
|
CP0382705
|
5-[(2R,5S)-5-methylmorpholin-2-yl]pyridin-2-amine
Show/Hide
|
C10H15N3O
|
1
|
| 1 |
Ki = 7100 nM
|
|
|
|
CP0847582
|
(+/-)-11-(3-(4-((4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine
Show/Hide
|
C37H46N6O2
|
1
|
| 1 |
Ki = 7384 nM
|
|
|
|
CP0470560
|
[(1R,2S,5S,6S,7S)-3-benzyl-2-phenyl-7-pyrrolidin-1-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
Ki = 7400 nM
|
|
|
|
CP0410131
|
N-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C23H24Cl2FN3O2
|
1
|
| 1 |
Ki = 7400 nM
|
|
|
|
CP0566757
|
3-(2,3-dichlorophenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H33Cl2N5S
|
1
|
| 1 |
Ki = 7501 nM
|
|
|
|
CP0282477
|
4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine
Show/Hide
|
C15H23NO2S
|
2
|
| 1 |
Ki = 7521 nM
|
|
|
| 2 |
Ki = 17550 nM
|
|
|
|
CP0405332
|
(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki = 7580 nM
|
|
|
|
CP0384675
|
N-(3-methylphenyl)-2-[4-(4-methylphenyl)piperidin-1-yl]acetamide
Show/Hide
|
C21H26N2O
|
1
|
| 1 |
Ki = 7824 nM
|
|
|
|
CP0467854
|
5-[(5S)-5-methyl-4-propylmorpholin-2-yl]-N,N-dipropylpyridin-2-amine
Show/Hide
|
C19H33N3O
|
1
|
| 1 |
Ki = 8240 nM
|
|
|
|
CP0396211
|
2-butyl-3,4-dihydro-1H-isoquinoline-6-carbonitrile
Show/Hide
|
C14H18N2
|
1
|
| 1 |
Ki = 8300 nM
|
|
|
|
CP0575068
|
2-N-[2-(1H-indol-3-yl)ethyl]-6-(4-phenylpiperazin-1-yl)-1,3,5-triazine-2,4-diamine
Show/Hide
|
C23H26N8
|
1
|
| 1 |
Ki = 8333 nM
|
|
|
|
CP0489688
|
N-[4-(4-phenylpiperazin-1-yl)butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H29N3OS
|
1
|
| 1 |
Ki = 8434 nM
|
|
|
|
CP0530508
|
3-(3-ethylimidazol-4-yl)-5-(trifluoromethyl)-1H-indole
Show/Hide
|
C14H12F3N3
|
1
|
| 1 |
Ki = 8710 nM
|
|
|
|
CP0542995
|
2-N-(2-anilinoethyl)-4-N-[2-(1H-indol-3-yl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C21H24N8
|
1
|
| 1 |
Ki = 8749 nM
|
|
|
|
CP0468995
|
3-(2-methoxyphenyl)-9-[2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]ethyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 9004 nM
|
|
|
|
CP0382714
|
N-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]-1,3-benzothiazole-5-carboxamide
Show/Hide
|
C26H31N3O4S
|
1
|
| 1 |
Ki = 9160 nM
|
|
|
|
CP0536765
|
3-(2-methoxyphenyl)-9-[4-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]butyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H39N5OS
|
1
|
| 1 |
Ki = 9248 nM
|
|
|
|
CP0528510
|
5-chloro-3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H11ClFN3
|
1
|
| 1 |
Ki = 9333 nM
|
|
|
|
CP0946433
|
N-(4-((4aS,10bR)-9-hydroxy-2,3,4a,5-tetrahydrochromeno[4,3-b][1,4]oxazin-4(10bH)-yl)butyl)-1H-indole-2-carboxamide
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
Ki = 9420 nM
|
|
|
|
CP0438519
|
N-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C27H32N2O5
|
1
|
| 1 |
Ki = 9450 nM
|
|
|
|
CP0396212
|
N-[[(1R,2R)-2-[(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)methyl]cyclopropyl]methyl]quinoline-4-carboxamide
Show/Hide
|
C25H24N4O
|
1
|
| 1 |
Ki = 9500 nM
|
|
|
|
CP0162156
|
3-(4-fluorophenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H34FN5S
|
1
|
| 1 |
Ki = 9792 nM
|
|
|
|
CP0215286
|
2-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'bipyridine]-1'-yl)-N-(m-tolyl)acetamide
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0283744
|
ABT-670
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0286510
|
6-(4-((1H-benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)pyridin-3-ol
Show/Hide
|
C17H19N5O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0378824
|
N-(4-fluoro-2-methylphenyl)-2-[4-(1-oxidopyridin-1-ium-2-yl)piperidin-1-yl]acetamide
Show/Hide
|
C19H22FN3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0372386
|
(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-yl)methanamine
Show/Hide
|
C21H24ClN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0501799
|
1-((1H-indol-2-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
Show/Hide
|
C20H21ClN2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0849920
|
(1R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hyrobromide
Show/Hide
|
C16H18BrNO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0320610
|
11-valeryloxynoraporphine
Show/Hide
|
C24H29NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0372853
|
11-Heptanoyloxy-N-n-propylnoraporphine
Show/Hide
|
C26H33NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0372855
|
11-Hexanoyloxy-N-n-propylnoraporphine
Show/Hide
|
C25H31NO2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0372857
|
Bis[N-propylnoraporphin-11-O-yl]succinate
Show/Hide
|
C42H44N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0467392
|
11-[2-(Benzyloxycarbonylamino)acetyloxy]-N-npropylnoraporphine
Show/Hide
|
C29H30N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0491417
|
11-Propionyloxy-N-n-propylnoraporphine
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C22H25NO2
|
1
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| 1 |
Ki > 10000 nM
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CP0510086
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Bis(N-propylnoraporphin-11-O-yl) glutamate
Show/Hide
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C43H46N2O4
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1
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| 1 |
Ki > 10000 nM
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CP0268685
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1,2,3,4,6,7,12,12b-Octahydro-indolo[2,3-a]quinolizine
Show/Hide
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C15H18N2
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1
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| 1 |
Ki > 10000 nM
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CP0386568
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3-methyl-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole
Show/Hide
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C15H20N2
|
1
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| 1 |
Ki > 10000 nM
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CP0394607
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N-[2-(1H-indol-3-yl)ethyl]-5-oxo-5-phenylpentanamide
Show/Hide
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C21H22N2O2
|
1
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| 1 |
Ki > 10000 nM
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CP0403287
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7,8,13,13b-tetrahydro-5H-benz[1,2]indolizino[8,7-b]indole
Show/Hide
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C18H16N2
|
1
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| 1 |
Ki > 10000 nM
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CP0403289
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1-phenyl-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole
Show/Hide
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C20H20N2
|
1
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| 1 |
Ki > 10000 nM
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CP0403290
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4-phenyloxolan-2-one
Show/Hide
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C10H10O2
|
1
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| 1 |
Ki > 10000 nM
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CP0403313
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6-allyl-4,5,6,7,8,13-hexahydrothieno[2,3-f][3]benzazecine
Show/Hide
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C18H21NS
|
1
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| 1 |
Ki > 10000 nM
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CP0403316
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3-phenyl-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole
Show/Hide
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C20H20N2
|
1
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| 1 |
Ki > 10000 nM
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CP0403385
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3,6-dimethyl-3,4,5,6,7,9,13,14-octahydro[3,2-g]azecine
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C19H23N3
|
1
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| 1 |
Ki > 10000 nM
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CP0403386
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ethyl 3-bromo-2-phenylpropanoate
Show/Hide
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C11H13BrO2
|
1
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| 1 |
Ki > 10000 nM
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CP0403387
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3-phenyltetrahydro-2H-pyran-2-one
Show/Hide
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C11H12O2
|
1
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| 1 |
Ki > 10000 nM
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CP0403389
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7-phenylethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine
Show/Hide
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C27H28N2
|
1
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| 1 |
Ki > 10000 nM
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CP0403391
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ethyl 5-bromo-5-phenylpentanoate
Show/Hide
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C13H17BrO2
|
1
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| 1 |
Ki > 10000 nM
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CP0403393
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3-methyl-8-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-azecino[5,4-b]indole
Show/Hide
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C22H26N2
|
1
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| 1 |
Ki > 10000 nM
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CP0403394
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6-phenyltetrahydro-2H-pyran-2-one
Show/Hide
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C11H12O2
|
1
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| 1 |
Ki > 10000 nM
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CP0419595
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5-hydroxy-N-[2-(1H-indol-3-yl)ethyl]-5-phenylpentanamide
Show/Hide
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C22H25NO2
|
1
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| 1 |
Ki > 10000 nM
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CP0422189
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ethyl 5-bromo-2-phenylpentanoate
Show/Hide
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C13H17BrO2
|
1
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| 1 |
Ki > 10000 nM
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CP0422265
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7-allyl-2,3-dimethoxy-5,6,7,8,9,14-hexahydrodibenz[d,g]azecine
Show/Hide
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C22H27NO2
|
1
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| 1 |
Ki > 10000 nM
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CP0422279
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5-methyl-1-phenyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizin-5-ium
Show/Hide
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C22H25N2+
|
1
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| 1 |
Ki > 10000 nM
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CP0428356
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N-[2-(1H-indol-3-yl)ethyl]-4-oxo-4-phenylbutanamide
Show/Hide
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C20H20N2O2
|
1
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| 1 |
Ki > 10000 nM
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CP0428357
|
Alpha-Phenyl-Gamma-Butyrolactone
Show/Hide
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C10H10O2
|
1
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| 1 |
Ki > 10000 nM
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CP0433459
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6-ethyl-5,6,7,8,13,14-hexahydroindolo[3,2-e]benzazonine
Show/Hide
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C20H22N2
|
1
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| 1 |
Ki > 10000 nM
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CP0433462
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3-methyl-5-phenyl-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole
Show/Hide
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C21H24N2
|
1
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| 1 |
Ki > 10000 nM
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CP0433463
|
2,3-dimethoxy-7-phenylethyl-5,6,7,8,9,14-hexahydrodibenz-[d,g]azecine
Show/Hide
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C27H31NO2
|
1
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| 1 |
Ki > 10000 nM
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CP0433464
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3-methyl-7-phenyl-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole
Show/Hide
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C21H24N2
|
1
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| 1 |
Ki > 10000 nM
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CP0433465
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3-methyl-1,2,3,4,5,6,7,8-octahydro-9H-azecino[5,4-b]indole
Show/Hide
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C16H22N2
|
1
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| 1 |
Ki > 10000 nM
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CP0441718
|
1-[2-(1H-indol-3-yl)ethyl]-6-phenylpiperidin-2-one
Show/Hide
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C22H23NO
|
1
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| 1 |
Ki > 10000 nM
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CP0441730
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1-[2-(1H-indol-3-yl)ethyl]-3-phenyl-2-piperidinone
Show/Hide
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C21H22N2O
|
1
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| 1 |
Ki > 10000 nM
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CP0442541
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12b-phenyl-1,2,3,4,6,7,12,12b-octahydroindolo-[2,3-a]quinolizine
Show/Hide
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C21H22N2
|
1
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| 1 |
Ki > 10000 nM
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CP0442543
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3-cyclopropylmethyl-1,2,3,4,5,6,7,8-octahydro-9H-azecino[5,4-b]indole
Show/Hide
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C19H26N2
|
1
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| 1 |
Ki > 10000 nM
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CP0442544
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1-phenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine
Show/Hide
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C21H22N2
|
1
|
| 1 |
Ki > 10000 nM
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CP0442555
|
2-phenyl-2,3,5,6,11,11b-hexahydro-1H-indolizino[8,7-b]indole
Show/Hide
|
C20H20N2
|
1
|
| 1 |
Ki > 10000 nM
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CP0442562
|
3-methyl-7-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-azecino[5,4-b]indole
Show/Hide
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C22H26N2
|
1
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| 1 |
Ki > 10000 nM
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CP0449796
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4-phenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine
Show/Hide
|
C21H22N2
|
1
|
| 1 |
Ki > 10000 nM
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CP0040673
|
2-[2-(3-chloro-4-methoxyphenyl)ethyl]-2,3,4,5-tetrahydro-1H-2-benzazepine
Show/Hide
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C19H22ClNO
|
1
|
| 1 |
Ki > 10000 nM
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CP0040675
|
3-methoxy-6,7,9,10,11,15b-hexahydro-5H-[2]benzazepino[1,2-a][2]benzazepine
Show/Hide
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C20H23NO
|
1
|
| 1 |
Ki > 10000 nM
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CP0277604
|
3-chloro-2-methoxy-5,6,8,9,10,14b-hexahydroisoquino[1,2-a][2]benzazepine
Show/Hide
|
C19H20ClNO
|
1
|
| 1 |
Ki > 10000 nM
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CP0373716
|
5-Methyl-4,5,6,7-tetrahydroindolo[4,3a,3-ef][3]benzazecine
Show/Hide
|
C19H20N2
|
1
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| 1 |
Ki > 10000 nM
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CP0429881
|
2,8,9,13b-Tetrahydro-6H-isoquino[2,1-b]pyrrolo[4,3,2-de]-isoquinoline
Show/Hide
|
C18H16N2
|
1
|
| 1 |
Ki > 10000 nM
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|
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CP0417882
|
2-Methoxy-11-allyloxy-N-methylaporphine
Show/Hide
|
C21H23NO2
|
1
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| 1 |
Ki > 10000 nM
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CP0417883
|
10-Allyl-11-hydroxy-N-methylaporphine
Show/Hide
|
C20H21NO
|
1
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| 1 |
Ki > 10000 nM
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CP0417884
|
10-Allyl-11-hydroxy-N-propylnoraporphine
Show/Hide
|
C22H25NO
|
1
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| 1 |
Ki > 10000 nM
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CP0417885
|
2-Methoxy-10-allyl-11-hydroxy-N-methylaporphine
Show/Hide
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C21H23NO2
|
1
|
| 1 |
Ki > 10000 nM
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CP0421895
|
11-Propargyloxy-N-propylnoraporphine
Show/Hide
|
C22H23NO
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0421899
|
11-Allyloxy-N-methylaporphine
Show/Hide
|
C20H21NO
|
1
|
| 1 |
Ki > 10000 nM
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CP0426885
|
8-(2-Methyl-2-buten-4-yl)-11-hydroxy-N-propylnoraporphine
Show/Hide
|
C24H29NO
|
1
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| 1 |
Ki > 10000 nM
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CP0426886
|
(R)-11-(allyloxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C22H25NO
|
1
|
| 1 |
Ki > 10000 nM
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CP0430913
|
(R)-11-(3-methylbut-2-enyloxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C24H29NO
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0439157
|
(5S,12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene
Show/Hide
|
C20H21NO
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0447706
|
(R)-11-(2-methylallyloxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Show/Hide
|
C23H27NO
|
1
|
| 1 |
Ki > 10000 nM
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|
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CP0447707
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(5R,12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene
Show/Hide
|
C20H21NO
|
1
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| 1 |
Ki > 10000 nM
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CP0458990
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(12R)-5,5-dimethyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),8,16(20),17-hexaene
Show/Hide
|
C23H27NO
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0464019
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(12R)-5-methyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaene
Show/Hide
|
C22H23NO
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0464020
|
10-(2-Methylallyl)-11-hydroxy-N-propylnoraporphine
Show/Hide
|
C23H27NO
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0470891
|
11-(2-Butynyloxy)-N-propylnoraporphine
Show/Hide
|
C23H25NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0502315
|
(12R)-5,6-dimethyl-13-propyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaene
Show/Hide
|
C23H25NO
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0502638
|
(12R)-5,13-dimethyl-4-oxa-13-azapentacyclo[10.7.1.02,10.03,7.016,20]icosa-1(19),2(10),3(7),5,8,16(20),17-heptaene
Show/Hide
|
C20H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0502639
|
11-Propargyloxy-N-methylaporphine
Show/Hide
|
C20H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0918962
|
N-Methyl-2'-methyl-2',3'-dihydrofuro[m]aporphine
Show/Hide
|
C20H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0057703
|
N-[2-(4-hydroxy-5-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-5-yl)ethyl]-2-methoxy-5-methylbenzamide
Show/Hide
|
C22H26N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0057753
|
5-[2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl]-5-azahexacyclo[5.4.1.02,6.03,10.04,8.09,12]dodecan-4-ol
Show/Hide
|
C28H31NO3
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0392876
|
(12R)-11,12-dimethyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene
Show/Hide
|
C21H24N2
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0392877
|
11-methyl-11,21-diazatetracyclo[12.7.0.03,8.015,20]henicosa-1(14),3,5,7,15,17,19-heptaene-12-carboxylic acid
Show/Hide
|
C21H22N2O2
|
1
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| 1 |
Ki > 10000 nM
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CP0052483
|
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-amide
Show/Hide
|
C24H24BrCl2N3O2
|
1
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| 1 |
Ki > 10000 nM
|
|
|
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CP0002070
|
1-(1H-Indol-3-yl)-2-propanamine
Show/Hide
|
C11H14N2
|
1
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| 1 |
Ki > 10000 nM
|
|
|
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CP0002071
|
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
Show/Hide
|
C17H22N2O
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0399600
|
2-[(6S,7S)-3-(benzenesulfonyl)-6-(methylamino)-6,7-dihydrocyclobuta[e]indol-7-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0432198
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2-[(4R,5R)-9-(benzenesulfonyl)-4-(dimethylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C20H22N2O3S
|
1
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| 1 |
Ki > 10000 nM
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|
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CP0466956
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2-[(6R,7R)-3-(benzenesulfonyl)-7-(methylamino)-6,7-dihydrocyclobuta[e]indol-6-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki > 10000 nM
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|
|
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CP0466957
|
2-[(6R,7S)-3-(benzenesulfonyl)-6-(methylamino)-6,7-dihydrocyclobuta[e]indol-7-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0466962
|
(2R,8S)-12-(benzenesulfonyl)-5,12-diazatetracyclo[7.7.0.02,8.011,15]hexadeca-1(9),10,13,15-tetraene
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0471145
|
2-[(4S,5S)-9-(benzenesulfonyl)-5-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-4-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
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CP0423253
|
N-[4-[1-(benzenesulfonyl)indol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0424448
|
N-[4-[1-(benzenesulfonyl)indol-3-yl]-5-ethyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0424449
|
N-[4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C22H21FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435386
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435387
|
N-[4-[1-(benzenesulfonyl)-2-methylindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435391
|
2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-3-methyl-1H-imidazo[1,2-a]pyrimidin-4-ium;bromide
Show/Hide
|
C22H19BrN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435398
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]-2-phenylacetamide
Show/Hide
|
C27H24N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
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CP0435400
|
N-[4-[1-(benzenesulfonyl)-5-fluoroindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0435406
|
N-[4-(5-methoxy-1-naphthalen-1-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C25H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438422
|
N-[5-methyl-4-(1-naphthalen-1-ylsulfonylindol-3-yl)-1H-imidazol-2-yl]propanamide
Show/Hide
|
C25H22N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438427
|
N-[4-(5-methoxy-1-naphthalen-2-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C25H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0438431
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440882
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C23H24N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440887
|
1-[3-[1-(benzenesulfonyl)indol-3-yl]-2-methyl-6,7-dihydro-5H-imidazo[1,2-a]pyrimidin-8-yl]ethanone
Show/Hide
|
C23H22N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0476615
|
1-[5-[1-(benzenesulfonyl)indol-3-yl]-6-methyl-2,3-dihydroimidazo[1,2-a]imidazol-1-yl]ethanone
Show/Hide
|
C22H20N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489682
|
N-[5-[1-(benzenesulfonyl)indol-3-yl]-1H-imidazol-2-yl]acetamide
Show/Hide
|
C19H16N4O3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489683
|
N-[5-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H18N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489684
|
N-[4-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-5-ethyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0489726
|
N-[5-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-1H-imidazol-2-yl]acetamide
Show/Hide
|
C20H17FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0519613
|
N-[4-[1-(3-fluorophenyl)sulfonyl-5-methoxyindol-3-yl]-5-methyl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C21H19FN4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0538216
|
N-[4-(5-methoxy-1-naphthalen-2-ylsulfonylindol-3-yl)-5-methyl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C26H24N4O4S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0423149
|
4-(2-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H35FN4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0098968
|
3-(3-ethylimidazol-4-yl)-1H-indole-5-carboxamide
Show/Hide
|
C14H14N4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0859942
|
3-(1-ethyl-1H-imidazol-5-yl)-1H-indole-5-sulfonamide
Show/Hide
|
C13H14N4O2S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0900183
|
methyl 3-(1-ethyl-1H-imidazol-5-yl)-1H-indole-5-carboxylate
Show/Hide
|
C15H15N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0384376
|
N-(3-methylphenyl)-2-[4-(5-methylpyridin-2-yl)piperidin-1-yl]acetamide
Show/Hide
|
C20H25N3O
|
2
|
| 1 |
Ki > 10000 nM
|
|
|
| 2 |
Ki > 50000 nM
|
|
|
|
CP0416633
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-(3-methylphenyl)acetamide
Show/Hide
|
C18H21ClN4O
|
2
|
| 1 |
Ki > 10000 nM
|
|
|
| 2 |
Ki > 50000 nM
|
|
|
|
CP0421663
|
5-chloro-3-(3-ethylimidazol-4-yl)-6-fluoro-1H-indole
Show/Hide
|
C13H11ClFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421833
|
5-ethoxy-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C15H17N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421834
|
5-bromo-3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H11BrFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421836
|
3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole-5-carboxamide
Show/Hide
|
C14H13FN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421838
|
3-(3-ethylimidazol-4-yl)-5-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0421839
|
3-(3-ethylimidazol-4-yl)-4,5-difluoro-1H-indole
Show/Hide
|
C13H11F2N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0426679
|
4,5-difluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9F2N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440388
|
3-(3-ethylimidazol-4-yl)-5-methyl-1H-indole
Show/Hide
|
C14H15N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440390
|
5-chloro-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12ClN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440391
|
5-bromo-3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12BrN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0440392
|
5-iodo-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H10IN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528449
|
5-bromo-4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9BrFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528508
|
3-(3-ethylimidazol-4-yl)-5-methoxy-1H-indole
Show/Hide
|
C14H15N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528509
|
3-(3-ethylimidazol-4-yl)-4-fluoro-5-methoxy-1H-indole
Show/Hide
|
C14H14FN3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0528511
|
4-fluoro-5-methoxy-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H12FN3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0537948
|
4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole-5-carboxamide
Show/Hide
|
C13H11FN4O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541120
|
5-chloro-4-fluoro-3-(3-methylimidazol-4-yl)-1H-indole
Show/Hide
|
C12H9ClFN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541121
|
3-(3-ethylimidazol-4-yl)-6-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0541126
|
3-(3-ethylimidazol-4-yl)-5-(trifluoromethoxy)-1H-indole
Show/Hide
|
C14H12F3N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0553532
|
3-(3-ethylimidazol-4-yl)-1H-indole
Show/Hide
|
C13H13N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0562326
|
3-(3-ethylimidazol-4-yl)-4-fluoro-1H-indole
Show/Hide
|
C13H12FN3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0000082
|
CAS_68647
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0853988
|
3-[3-(4-Benzoylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H27FN4O4
|
1
|
| 1 |
Ki = 10080 nM
|
|
|
|
CP0471921
|
7-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C27H34N2O5
|
1
|
| 1 |
Ki = 10100 nM
|
|
|
|
CP0063610
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-fluorobutyl]-1-benzofuran-2-carboxamide
Show/Hide
|
C26H31ClFN3O3
|
1
|
| 1 |
Ki = 10800 nM
|
|
|
|
CP0239897
|
N-[(3R)-4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O3
|
1
|
| 1 |
Ki = 10800 nM
|
|
|
|
CP0003459
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H37N5OS
|
1
|
| 1 |
Ki = 10895 nM
|
|
|
|
CP0530348
|
2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)pyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C33H36N4O4
|
1
|
| 1 |
Ki = 11160 nM
|
|
|
|
CP0043573
|
1,2,3,4-Tetrahydro-isoquinoline-7-carbonitrile
Show/Hide
|
C10H10N2
|
1
|
| 1 |
Ki = 11400 nM
|
|
|
|
CP0157762
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O3
|
2
|
| 1 |
Ki = 11400 nM
|
|
|
| 2 |
Ki = 13200 nM
|
|
|
|
CP0423855
|
[(1S,2R,5R,6R,7R)-3-benzyl-7-(diethylamino)-2-pyridin-2-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C23H31N3O
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0475616
|
[(1R,2S,5S,6S,7S)-3-benzyl-7-(diethylamino)-2-phenyl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
Ki = 12000 nM
|
|
|
|
CP0438434
|
N-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C25H28ClN3OS
|
1
|
| 1 |
Ki = 12046 nM
|
|
|
|
CP0492203
|
4-[5-[3-[3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecan-9-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-N,N-dimethylaniline
Show/Hide
|
C30H42N6OS
|
1
|
| 1 |
Ki = 12137 nM
|
|
|
|
CP0541054
|
N-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C25H28ClN3O
|
1
|
| 1 |
Ki = 12143 nM
|
|
|
|
CP0483049
|
9-[3-[(5-cyclohexyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H43N5OS
|
1
|
| 1 |
Ki = 12584 nM
|
|
|
|
CP0542760
|
2-N-[2-(1H-indol-3-yl)ethyl]-4-N-[2-(2-methoxyphenyl)ethyl]-1,3,5-triazine-2,4,6-triamine
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 13300 nM
|
|
|
|
CP0503881
|
N-[4-[4-(N-acetyl-2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C29H35N3O3
|
1
|
| 1 |
Ki = 13350 nM
|
|
|
|
CP0463359
|
N-heptan-4-yl-1H-indole-2-carboxamide
Show/Hide
|
C16H22N2O
|
1
|
| 1 |
Ki = 13400 nM
|
|
|
|
CP0542764
|
2-N-[2-(1H-indol-3-yl)ethyl]-6-[4-(2-methoxyphenyl)piperazin-1-yl]-1,3,5-triazine-2,4-diamine
Show/Hide
|
C24H28N8O
|
1
|
| 1 |
Ki = 13460 nM
|
|
|
|
CP0063619
|
N-[(3S)-4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-hydroxybutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H33ClN4O3
|
1
|
| 1 |
Ki = 13500 nM
|
|
|
|
CP0425933
|
N-[4-[4-[2-(trifluoromethyl)quinolin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C26H27F3N6O
|
1
|
| 1 |
Ki = 13567 nM
|
|
|
|
CP0208172
|
N-butyl-1H-indole-2-carboxamide
Show/Hide
|
C13H16N2O
|
1
|
| 1 |
Ki = 13570 nM
|
|
|
|
CP0416961
|
3-[3-[3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecan-9-yl]propylsulfanyl]-5-phenyl-1,2,4-triazol-4-amine
Show/Hide
|
C27H36N6OS
|
1
|
| 1 |
Ki = 13904 nM
|
|
|
|
CP0389447
|
1-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-[4-(4-phenylphenyl)triazol-1-yl]butan-2-ol
Show/Hide
|
C28H29Cl2N5O
|
1
|
| 1 |
Ki = 15100 nM
|
|
|
|
CP0492205
|
9-[3-[[5-(4-fluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H36FN5OS
|
1
|
| 1 |
Ki = 15768 nM
|
|
|
|
CP0377493
|
2-[(6S,7R)-3-(benzenesulfonyl)-7-(methylamino)-6,7-dihydrocyclobuta[e]indol-6-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 15848.93 nM
|
|
|
|
CP0399598
|
2-[(4S,5R)-9-(benzenesulfonyl)-4-(methylamino)-9-azatricyclo[6.3.0.03,6]undeca-1,3(6),7,10-tetraen-5-yl]ethanol
Show/Hide
|
C19H20N2O3S
|
1
|
| 1 |
Ki = 15848.93 nM
|
|
|
|
CP0458243
|
[(1R,2S,5R,6R,7R)-3-benzyl-2-methyl-7-pyrrolidin-1-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C19H28N2O
|
1
|
| 1 |
Ki = 16000 nM
|
|
|
|
CP0435437
|
N-[4-[4-(3-methylphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C26H31N3OS
|
1
|
| 1 |
Ki = 16318 nM
|
|
|
|
CP0521214
|
N-[4-[4-(4-methoxyphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C26H31N3O2S
|
1
|
| 1 |
Ki >= 17000 nM
|
|
|
|
CP0384496
|
2-[9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecan-3-yl]phenol
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 17595 nM
|
|
|
|
CP0444016
|
2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenylpyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H32N4O2
|
1
|
| 1 |
Ki = 17670 nM
|
|
|
|
CP0397790
|
1-[4-(2,3-dichlorophenyl)piperazin-1-yl]-4-(4-naphthalen-2-yltriazol-1-yl)butan-2-ol
Show/Hide
|
C26H27Cl2N5O
|
1
|
| 1 |
Ki = 18800 nM
|
|
|
|
CP0417010
|
N-[(3S)-4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H32ClFN4O2
|
1
|
| 1 |
Ki = 18900 nM
|
|
|
|
CP0416962
|
3-(4-fluoro-2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H36FN5OS
|
1
|
| 1 |
Ki = 19634 nM
|
|
|
|
CP0411136
|
9-[3-[[5-(2-fluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H36FN5OS
|
1
|
| 1 |
Ki = 19655 nM
|
|
|
|
CP0519090
|
N-[4-[4-(4-cyanophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
|
C26H28N4OS
|
1
|
| 1 |
Ki > 20000 nM
|
|
|
|
CP0887578
|
3-[3-(4-Benzylpiperazin-1-yl)-2-hydroxypropyl]-5-(4-fluorophenyl)-5-methylimidazolidine-2,4-dione
Show/Hide
|
C24H29FN4O3
|
1
|
| 1 |
Ki = 20030 nM
|
|
|
|
CP0063606
|
N-[4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
|
C26H32ClFN4O2
|
1
|
| 1 |
Ki = 20800 nM
|
|
|
|
CP0416958
|
8-(2-methoxyphenyl)-2-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,8-diazaspiro[4.5]decane
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 21098 nM
|
|
|
|
CP0519115
|
7-[(E)-4-[(2R,5S)-2-(6-aminopyridin-3-yl)-5-methylmorpholin-4-yl]but-2-enoxy]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
|
C23H28N4O3
|
1
|
| 1 |
Ki = 21100 nM
|
|
|
|
CP0416710
|
3-[2-fluoro-4-(trifluoromethyl)phenyl]-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C28H33F4N5S
|
1
|
| 1 |
Ki = 21172 nM
|
|
|
|
CP0547878
|
2-(2-methoxyphenyl)-6-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,6-diazaspiro[3.3]heptane
Show/Hide
|
C24H29N5OS
|
1
|
| 1 |
Ki = 21216 nM
|
|
|
|
CP0468878
|
N-[(3R)-4-[4-(3-chloro-5-ethyl-2-methoxyphenyl)piperazin-1-yl]-3-fluorobutyl]-1H-indole-2-carboxamide
Show/Hide
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C26H32ClFN4O2
|
1
|
| 1 |
Ki = 21400 nM
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CP0876922
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N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide hydrochloride
Show/Hide
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C23H27Cl3N4O
|
1
|
| 1 |
Ki > 23889 nM
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CP0400254
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N-[4-[4-[2-methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperazin-1-yl]butyl]imidazo[1,2-a]pyridine-2-carboxamide
Show/Hide
|
C22H26F3N7O
|
1
|
| 1 |
Ki = 24938 nM
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CP0519088
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N-[4-[4-(4-methylphenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
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C26H31N3OS
|
1
|
| 1 |
Ki = 24994 nM
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CP0535809
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8-butyl-2-(2-methoxyphenyl)-2,8-diazaspiro[4.5]decane
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C19H30N2O
|
1
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| 1 |
Ki = 25823 nM
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CP0477400
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7-butyl-2-(2-methoxyphenyl)-2,7-diazaspiro[4.4]nonane
Show/Hide
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C18H28N2O
|
1
|
| 1 |
Ki = 26050 nM
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CP0384492
|
3-(2-fluorophenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H34FN5S
|
1
|
| 1 |
Ki = 26253 nM
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CP0541816
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9-butyl-3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C20H32N2O
|
1
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| 1 |
Ki = 26739 nM
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CP0462359
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N-[4-[[(4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-yl]oxy]butyl]-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Show/Hide
|
C26H32N4O4
|
1
|
| 1 |
Ki = 27000 nM
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CP0466447
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N-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]-4-thiophen-3-ylbenzamide
Show/Hide
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C25H28ClN3OS
|
1
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| 1 |
Ki = 27359 nM
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CP0437100
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1-(2-methoxyphenyl)-7-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,7-diazaspiro[3.5]nonane
Show/Hide
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C26H33N5OS
|
1
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| 1 |
Ki = 29300 nM
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CP0396207
|
N-pentan-2-yl-1H-indole-2-carboxamide
Show/Hide
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C14H18N2O
|
1
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| 1 |
Ki > 30000 nM
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CP0391044
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4-thiophen-3-yl-N-[4-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]benzamide
Show/Hide
|
C26H28F3N3OS
|
1
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| 1 |
Ki > 30000 nM
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CP0384711
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3-(2-methoxyphenyl)-9-[3-(1-methyl-5-phenylimidazol-2-yl)sulfanylpropyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H38N4OS
|
1
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| 1 |
Ki = 35720 nM
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CP0407283
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2-(2-methoxyphenyl)-7-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,7-diazaspiro[3.5]nonane
Show/Hide
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C26H33N5OS
|
1
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| 1 |
Ki = 37579 nM
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CP0429033
|
[(1S,2R,5S,6S,7S)-3-benzyl-7-(diethylamino)-2-methyl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C19H30N2O
|
1
|
| 1 |
Ki = 38000 nM
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CP0417063
|
2-[6-[4-(4-methoxyphenyl)piperazin-1-yl]hexyl]benzo[de]isoquinoline-1,3-dione
Show/Hide
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C29H33N3O3
|
1
|
| 1 |
Ki = 40040 nM
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CP0409127
|
[(1R,2S,5S,6S,7S)-3-benzyl-7-(diethylamino)-2-pyridin-2-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C23H31N3O
|
1
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| 1 |
Ki = 42000 nM
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CP0384367
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-(3-ethylphenyl)acetamide
Show/Hide
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C19H23ClN4O
|
1
|
| 1 |
Ki = 46260 nM
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CP0384491
|
3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-pyridin-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H36N6OS
|
1
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| 1 |
Ki = 48584 nM
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CP0411143
|
(11R)-5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide
Show/Hide
|
C21H18N2O3S2
|
1
|
| 1 |
Ki > 50000 nM
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CP0384366
|
2-[4-(4-chlorophenyl)piperidin-1-yl]-N-(3-methylphenyl)acetamide
Show/Hide
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C20H23ClN2O
|
1
|
| 1 |
Ki > 50000 nM
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CP0384381
|
N-pyridin-3-yl-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
Show/Hide
|
C16H19N5O
|
1
|
| 1 |
Ki > 50000 nM
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CP0384383
|
2-(4-pyridin-2-ylpiperazin-1-yl)-N-pyrimidin-5-ylacetamide
Show/Hide
|
C15H18N6O
|
1
|
| 1 |
Ki > 50000 nM
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|
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CP0384678
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-pyrimidin-5-ylacetamide
Show/Hide
|
C15H17ClN6O
|
1
|
| 1 |
Ki > 50000 nM
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CP0421988
|
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-pyridin-3-ylacetamide
Show/Hide
|
C16H18ClN5O
|
1
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| 1 |
Ki > 50000 nM
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CP0431611
|
4-[(2-chlorophenyl)sulfonylmethyl]-6-(4-methylpiperazin-1-yl)-1,3,5-triazin-2-amine
Show/Hide
|
C15H19ClN6O2S
|
1
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| 1 |
Ki = 50140 nM
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CP0396205
|
1,2,3,4-tetrahydroisoquinoline-6-carbonitrile
Show/Hide
|
C10H10N2
|
1
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| 1 |
Ki = 53800 nM
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CP0407284
|
3-[9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecan-3-yl]benzonitrile
Show/Hide
|
C28H34N6S
|
1
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| 1 |
Ki = 57101 nM
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CP0559802
|
4,4-dimethyl-1-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperidine
Show/Hide
|
C19H28N4S
|
1
|
| 1 |
Ki = 59994 nM
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CP0547876
|
7-(2-methoxyphenyl)-2-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,7-diazaspiro[3.4]octane
Show/Hide
|
C25H31N5OS
|
1
|
| 1 |
Ki = 60152 nM
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|
|
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CP0403227
|
3-(2,4-dimethoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C29H39N5O2S
|
1
|
| 1 |
Ki = 65229 nM
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|
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CP0423853
|
[(1S,2R,5S,6S,7S)-3-benzyl-2-methyl-7-pyrrolidin-1-yl-3-azabicyclo[3.2.0]heptan-6-yl]methanol
Show/Hide
|
C19H28N2O
|
1
|
| 1 |
Ki = 66000 nM
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|
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CP0384478
|
1-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
Show/Hide
|
C16H23N5S
|
1
|
| 1 |
Ki = 74272 nM
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CP0573634
|
9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3-pyridin-2-yl-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C26H34N6S
|
1
|
| 1 |
Ki = 83671 nM
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|
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CP0562951
|
1-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperidine
Show/Hide
|
C17H24N4S
|
1
|
| 1 |
Ki = 98462 nM
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|
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CP0548209
|
3-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C16H24N2O
|
1
|
| 1 |
Ki = 99379 nM
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|
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CP0390315
|
(R)-Modafinil
Show/Hide
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C15H15NO2S
|
1
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| 1 |
Ki > 100000 nM
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CP0396215
|
N-propan-2-yl-1H-indole-2-carboxamide
Show/Hide
|
C12H14N2O
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
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CP0470556
|
N-(cyclopropylmethyl)-1H-indole-2-carboxamide
Show/Hide
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C13H14N2O
|
1
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| 1 |
Ki > 100000 nM
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CP0416963
|
4-methyl-3-phenyl-5-propylsulfanyl-1,2,4-triazole
Show/Hide
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C12H15N3S
|
1
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| 1 |
Ki = 180375 nM
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CP0442525
|
3-methyl-4-phenyl-1,2,3,4,5,6,7,8-octahydroazonino[5,4-b]indole
Show/Hide
|
C21H24N2
|
1
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| 1 |
Ki ~ 100 nM
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CP0403384
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3-methyl-4-phenyl-2,3,4,5,6,7,8,9-octahydro-1H-azecino[5,4-b]indole
Show/Hide
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C22H26N2
|
1
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| 1 |
Ki ~ 500 nM
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CP0409214
|
N-[4-[4-(8-oxo-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C33H32N2O2S
|
1
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| 1 |
Ki > 1000 nM
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CP0511133
|
(E)-N-[4-[4-(2-methoxyanilino)piperidin-1-yl]butyl]-3-phenylprop-2-enamide
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
Ki > 1000 nM
|
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CP0541733
|
N-[4-[4-(2-methoxy-N-propanoylanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
Show/Hide
|
C30H37N3O3
|
1
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| 1 |
Ki > 1000 nM
|
|
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CP0415505
|
(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[6-[3-[(2R)-2-amino-2-carboxyethyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]hexanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-6-[[(E)-[4-[ditert-butyl(fluoro)silyl]phenyl]methylideneamino]oxycarbonylamino]hexanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C87H133FN20O22SSi
|
1
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| 1 |
Ki > 1000 nM
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CP0499327
|
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Show/Hide
|
C52H101N27O11
|
1
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| 1 |
Ki > 1000 nM
|
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CP0553680
|
(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-oxopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carboxylic acid
Show/Hide
|
C55H102N20O13S
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0555954
|
(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Show/Hide
|
C41H60N14O9
|
1
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| 1 |
Ki > 1000 nM
|
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CP0400236
|
3-methyl-8-[(2-methylphenyl)methylamino]-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C25H28N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0400238
|
3-methyl-8-naphthalen-2-yl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C27H25NO
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0400239
|
3-methyl-8-(2-methylphenyl)-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C24H25NO
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0400240
|
7-(aminomethyl)-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0410524
|
8-(diethylamino)-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C21H28N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
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CP0410525
|
3-methyl-5-phenyl-8-pyrrol-1-yl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C21H22N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0410526
|
3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-amine
Show/Hide
|
C17H20N2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0410530
|
8-amino-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0410531
|
8-[(3-chlorophenyl)methylamino]-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C24H25ClN2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0424268
|
3-methyl-8-[(4-methylphenyl)methylamino]-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C25H28N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0424270
|
3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-amine
Show/Hide
|
C17H20N2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
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CP0426632
|
3-methyl-8-(3-methylphenyl)-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C24H25NO
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0443430
|
3-methyl-8-(4-methylphenyl)-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C24H25NO
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0443431
|
N,N,3-trimethyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-amine
Show/Hide
|
C19H24N2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0443432
|
7-amino-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0443434
|
8-(benzylamino)-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C24H26N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0443435
|
8-(4-hydroxyphenyl)-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C23H23NO2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0487148
|
N-(7-hydroxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-yl)acetamide
Show/Hide
|
C19H22N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0509154
|
3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C17H19NO
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0509155
|
7-methyl-5-phenyl-5,6,8,9-tetrahydro-3H-[1,3]oxazolo[5,4-h][3]benzazepin-2-one
Show/Hide
|
C18H18N2O2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0509156
|
7-methyl-5-phenyl-5,6,8,9-tetrahydro-[1,3]oxazolo[5,4-h][3]benzazepine
Show/Hide
|
C18H18N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0509157
|
3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
Show/Hide
|
C17H19NO
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0509165
|
N,3-dimethyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-amine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0509167
|
3-methyl-8-[(3-methylphenyl)methylamino]-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol
Show/Hide
|
C25H28N2O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0529531
|
7-(hydroxymethyl)-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol
Show/Hide
|
C18H21NO2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0530690
|
7-methyl-2-(4-methylpiperazin-1-yl)-5-phenyl-5,6,8,9-tetrahydro-[1,3]oxazolo[5,4-h][3]benzazepine
Show/Hide
|
C23H28N4O
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0540059
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8-methyl-6-phenyl-6,7,9,10-tetrahydro-4H-[1,4]oxazino[2,3-h][3]benzazepin-3-one
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C19H20N2O2
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1
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| 1 |
Ki > 1000 nM
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CP0392142
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7-cyclopropylmethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine
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C23H26N2
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1
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| 1 |
Ki > 5000 nM
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CP0392149
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2,3-dimethoxy-7-methyl-5,6,7,8,9,14-hexahydrodibenzo[d,g]azecine
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C20H25NO2
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1
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| 1 |
Ki > 5000 nM
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CP0230384
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(-)-Tetrahydropalmatine
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C21H25NO4
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1
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| 1 |
Ki > 5000 nM
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CP0440159
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(1S)-17-methoxy-5,7-dioxa-13-azapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-2,4(8),9,15(20),16,18-hexaen-16-ol
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C19H19NO4
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1
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| 1 |
Ki > 5000 nM
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CP0443214
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(13aS)-2,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-3,9-diol
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C19H21NO4
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1
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| 1 |
Ki > 5000 nM
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CP0478825
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N-butyl-4-thiophen-3-ylbenzamide
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C15H17NOS
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1
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| 1 |
Ki > 5000 nM
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