General Information of the Compound
Compound ID
CP0854344
Compound Name
(R)-1-(4-Iodophenyl)-4-(4-(7-hydroxychroman-2-yl)-3-azabutyl)-piperazine oxalate
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Structure
Formula
C24H30IN3O6
Molecular Weight
583.423
Canonical SMILES
O=C(O)C(=O)O.Oc1ccc2c(c1)O[C@@H](CNCCN1CCN(c3ccc(I)cc3)CC1)CC2
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InChI
InChI=1S/C22H28IN3O2.C2H2O4/c23-18-3-5-19(6-4-18)26-13-11-25(12-14-26)10-9-24-16-21-8-2-17-1-7-20(27)15-22(17)28-21;3-1(4)2(5)6/h1,3-7,15,21,24,27H,2,8-14,16H2;(H,3,4)(H,5,6)/t21-;/m1./s1
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InChIKey
YNLXAVVGSZRKMZ-ZMBIFBSDSA-N
Physicochemical Property
logP
2.2578
Rotatable Bonds
6
Heavy Atom Count
34
Polar Areas
122.57
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
7
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76321555
ChEMBL ID
CHEMBL3115578
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 1.585 nM
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