Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]pyrazolo[1,5-a]pyridine-3-carbaldehyde
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 PubChem ID
CID: 25072941
SID: 56411191
Canonical SMILES
COc1ccccc1N1CCN(CCCCOc2ccc3c(C=O)cnn3c2)CC1
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Compound Formula C23H28N4O3
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 7.7 nM
   TI
   LI
   LO
   TS
2
Ki = 7.8 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  4
1
EC50 = 2.6 nM
   TI
   LI
   LO
   TS
2
EC50 = 4.2 nM
   TI
   LI
   LO
   TS
3
EC50 = 7.7 nM
   TI
   LI
   LO
   TS
4
EC50 = 10.1 nM
   TI
   LI
   LO
   TS