General Information of the Compound
Compound ID
CP0883762
Compound Name
(+/-)-trans-2-(4-Hydroxyphenyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline-8,9-diol Hydrobromide
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Structure
Formula
C19H22BrNO3
Molecular Weight
392.293
Canonical SMILES
Br.Oc1ccc([C@H]2CN[C@@H]3CCc4cc(O)c(O)cc4[C@H]3C2)cc1
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InChI
InChI=1S/C19H21NO3.BrH/c21-14-4-1-11(2-5-14)13-7-16-15-9-19(23)18(22)8-12(15)3-6-17(16)20-10-13;/h1-2,4-5,8-9,13,16-17,20-23H,3,6-7,10H2;1H/t13-,16-,17-;/m1./s1
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InChIKey
HVXKRBGIMSFFEJ-WGUYJYMSSA-N
Physicochemical Property
logP
3.5568
Rotatable Bonds
1
Heavy Atom Count
24
Polar Areas
72.72
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71454926
SID: 163447651
ChEMBL ID
CHEMBL2158636
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01195, D(1A) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 550 nM
   TI
   LI
   LO
   TS
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 490 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 50 nM
   TI
   LI
   LO
   TS