General Information of the Compound
Compound ID
CP0499327
Compound Name
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
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Structure
Formula
C52H101N27O11
Molecular Weight
1280.558
Canonical SMILES
NCCCC[C@H](NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
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InChI
InChI=1S/C52H101N27O11/c53-21-3-1-12-30(72-39(81)29(55)11-5-23-67-48(57)58)40(82)73-31(13-2-4-22-54)42(84)77-35(16-8-26-70-51(63)64)46(88)79-28-10-18-37(79)45(87)76-34(19-20-38(56)80)44(86)75-32(14-6-24-68-49(59)60)41(83)74-33(15-7-25-69-50(61)62)43(85)78-36(47(89)90)17-9-27-71-52(65)66/h29-37H,1-28,53-55H2,(H2,56,80)(H,72,81)(H,73,82)(H,74,83)(H,75,86)(H,76,87)(H,77,84)(H,78,85)(H,89,90)(H4,57,58,67)(H4,59,60,68)(H4,61,62,69)(H4,63,64,70)(H4,65,66,71)/t29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1
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InChIKey
XOBCYBIYOHGQPS-IZROAPMXSA-N
Physicochemical Property
logP
-8.37725
Rotatable Bonds
47
Heavy Atom Count
90
Polar Areas
691.96
Hydrogen Bond Donor Count
27
Hydrogen Bond Acceptor Count
18
Complexity
90

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 90643434
ChEMBL ID
CHEMBL3265328
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS