Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-pyridin-3-yl-2-(4-pyridin-2-ylpiperazin-1-yl)acetamide
    Show/Hide
 PubChem ID
CID: 155568867
Canonical SMILES
O=C(CN1CCN(CC1)c1ccccn1)Nc1cccnc1
    Show/Hide
Compound Formula C16H19N5O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 1965 nM
   TI
   LI
   LO
   TS
2
EC50 = 48503 nM
   TI
   LI
   LO
   TS
3
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki > 50000 nM
   TI
   LI
   LO
   TS