Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(E)-4-[4-(2,3-dichlorophenyl)piperazin-1-yl]but-2-enyl]-4-pyridin-2-ylbenzamide
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 PubChem ID
CID: 11477180
SID: 16577963
Canonical SMILES
Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc(cc3)-c3ccccn3)CC2)c1Cl
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Compound Formula C26H26Cl2N4O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 80.9 nM
   TI
   LI
   LO
   TS
2
Ki = 74 nM
   TI
   LI
   LO
   TS
3
Ki = 93.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 93.3 nM