General Information of the Compound
Compound ID
CP0854346
Compound Name
(R)-2-[(3-Iodobenzylamino)methyl]chroman-7-ol oxalate
    Show/Hide
Structure
Formula
C19H20INO6
Molecular Weight
485.274
Canonical SMILES
O=C(O)C(=O)O.Oc1ccc2c(c1)O[C@@H](CNCc1cccc(I)c1)CC2
    Show/Hide
InChI
InChI=1S/C17H18INO2.C2H2O4/c18-14-3-1-2-12(8-14)10-19-11-16-7-5-13-4-6-15(20)9-17(13)21-16;3-1(4)2(5)6/h1-4,6,8-9,16,19-20H,5,7,10-11H2;(H,3,4)(H,5,6)/t16-;/m1./s1
    Show/Hide
InChIKey
YQZZGWRXVUXVCC-PKLMIRHRSA-N
Physicochemical Property
logP
2.6358
Rotatable Bonds
4
Heavy Atom Count
27
Polar Areas
116.09
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
5
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 76325149
ChEMBL ID
CHEMBL3115575
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 0.03162 nM
   TI
   LI
   LO
   TS