Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
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 PubChem ID
CID: 3038495
SID: 14782328
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1
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Compound Formula C26H31N3O2
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
Ki = 61 nM
   TI
   LI
   LO
   TS
2
Ki = 200 nM
   TI
   LI
   LO
   TS
3
Ki = 220 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 33.6 nM
   TI
   LI
   LO
   TS
2
Ki = 52 nM
   TI
   LI
   LO
   TS
3
Ki = 186 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 208.93 nM
2 Ki = 210 nM