Brief Information of the Compound and Protein
Compound Name
2-(4-phenylpiperidin-1-yl)-N-(m-tolyl)acetamide
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PubChem ID
CID: 16094666
SID: 24741043
Canonical SMILES
Cc1cccc(NC(=O)CN2CCC(CC2)c2ccccc2)c1
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Compound Formula C20H24N2O
Compound Structure
Protein Name
D(2) dopamine receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
IC50 = 7692 nM
   TI
   LI
   LO
   TS
2
IC50 = 16447 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
Ki = 127 nM
   TI
   LI
   LO
   TS
2
Ki = 821 nM
   TI
   LI
   LO
   TS