Brief Information of the Compound and Protein
| Compound Name |
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
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PubChem ID | |||||
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Compound Structure |
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| Protein Name |
D(2) dopamine receptor
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Protein Classification |
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
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| Uniprot ID | Gene Name | DRD2 |
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Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Biochemical Assays
| 1 | IC50 = 7.09 nM | ||
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| 2 | Ki = 0.44 nM | ||
| 3 | Ki = 2.2 nM | ||
| 4 | Ki = 2.7 nM | ||
| 5 | Ki = 3.1 nM | ||
| 6 | Ki = 3.3 nM | ||
| 7 | Ki = 3.57 nM | ||
| 8 | Ki = 3.8 nM | ||
| 9 | Ki = 3.9 nM | ||
| 10 | Ki = 5.9 nM | ||
| 11 | Ki = 6.166 nM | ||
| 12 | Ki = 6.4 nM | ||
| 13 | Ki = 10 nM | ||