General Information of the Compound
Compound ID
CP0372857
Compound Name
Bis[N-propylnoraporphin-11-O-yl]succinate
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Structure
Formula
C42H44N2O4
Molecular Weight
640.824
Canonical SMILES
CCCN1CCc2cccc3-c4cc(OC(=O)CCC(=O)Oc5cccc6C[C@H]7N(CCC)CCc8cccc(c78)-c56)ccc4C[C@@H]1c23
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InChI
InChI=1S/C42H44N2O4/c1-3-20-43-22-18-27-8-5-11-32-34-26-31(15-14-29(34)24-35(43)40(27)32)47-38(45)16-17-39(46)48-37-13-7-10-30-25-36-41-28(19-23-44(36)21-4-2)9-6-12-33(41)42(30)37/h5-15,26,35-36H,3-4,16-25H2,1-2H3/t35-,36-/m1/s1
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InChIKey
BCYVFMPPKQJVKU-LQFQNGICSA-N
Physicochemical Property
logP
8.0424
Rotatable Bonds
9
Heavy Atom Count
48
Polar Areas
59.08
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
48

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44579033
ChEMBL ID
CHEMBL455318
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01448, 5-hydroxytryptamine receptor 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS