Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(6S)-6-[4-[3-[(Z)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
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 PubChem ID
CID: 137659990
Canonical SMILES
CCCN(CCCCOc1ccn2ncc(\C=N/O)c2c1)[C@H]1CCc2c(O)cccc2C1
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Compound Formula C25H32N4O3
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.87 nM
   TI
   LI
   LO
   TS
2
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
EC50 = 0.17 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.21 nM
   TI
   LI
   LO
   TS
3
EC50 = 0.49 nM
   TI
   LI
   LO
   TS
4
EC50 = 0.67 nM
   TI
   LI
   LO
   TS
5
EC50 = 0.96 nM
   TI
   LI
   LO
   TS
6
EC50 = 1.7 nM
   TI
   LI
   LO
   TS
7
EC50 = 11.9 nM
   TI
   LI
   LO
   TS
8
EC50 = 13.2 nM
   TI
   LI
   LO
   TS