Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3',4',-5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-yl)-N-(m-tolyl)acetamide
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 PubChem ID
CID: 10425450
SID: 15444520
Canonical SMILES
Cc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1
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Compound Formula C19H23N3O
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 5846 nM
   TI
   LI
   LO
   TS
2
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 251 nM
   TI
   LI
   LO
   TS
2
Ki = 2900 nM
   TI
   LI
   LO
   TS
3
Ki = 6250 nM
   TI
   LI
   LO
   TS