General Information of the Compound
Compound ID
CP0560743
Compound Name
N-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butyl]-4-[4-[[1-[2-[2-[2-[2-[4-[[4-[4-[4-[2,3-dihydro-1H-inden-2-yl(propyl)amino]butylcarbamoyl]phenyl]phenoxy]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methoxy]phenyl]benzamide
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Formula
C72H88N10O7
Molecular Weight
1205.559
Canonical SMILES
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccc(OCc2cn(CCOCCOCCOCCn3cc(COc4ccc(cc4)-c4ccc(cc4)C(=O)NCCCCN(CCC)C4Cc5ccccc5C4)nn3)nn2)cc1)C1Cc2ccccc2C1
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InChI
InChI=1S/C72H88N10O7/c1-3-35-79(67-47-61-13-5-6-14-62(61)48-67)37-11-9-33-73-71(83)59-21-17-55(18-22-59)57-25-29-69(30-26-57)88-53-65-51-81(77-75-65)39-41-85-43-45-87-46-44-86-42-40-82-52-66(76-78-82)54-89-70-31-27-58(28-32-70)56-19-23-60(24-20-56)72(84)74-34-10-12-38-80(36-4-2)68-49-63-15-7-8-16-64(63)50-68/h5-8,13-32,51-52,67-68H,3-4,9-12,33-50,53-54H2,1-2H3,(H,73,83)(H,74,84)
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InChIKey
ZHXPQJBVBDKOKM-UHFFFAOYSA-N
Physicochemical Property
logP
10.8904
Rotatable Bonds
38
Heavy Atom Count
89
Polar Areas
172.25
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
15
Complexity
89

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4748201
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 292 nM
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