General Information of the Compound
Compound ID
CP0849299
Compound Name
(R)-2-[(4-(4-Fluorobutoxy)benzylamino)methyl]chroman-7-ol oxalate
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Structure
Formula
C23H28FNO7
Molecular Weight
449.475
Canonical SMILES
O=C(O)C(=O)O.Oc1ccc2c(c1)O[C@@H](CNCc1ccc(OCCCCF)cc1)CC2
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InChI
InChI=1S/C21H26FNO3.C2H2O4/c22-11-1-2-12-25-19-8-3-16(4-9-19)14-23-15-20-10-6-17-5-7-18(24)13-21(17)26-20;3-1(4)2(5)6/h3-5,7-9,13,20,23-24H,1-2,6,10-12,14-15H2;(H,3,4)(H,5,6)/t20-;/m1./s1
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InChIKey
KUVBELKHWOCLLE-VEIFNGETSA-N
Physicochemical Property
logP
3.1597
Rotatable Bonds
9
Heavy Atom Count
32
Polar Areas
125.32
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
6
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 76325151
ChEMBL ID
CHEMBL3115579
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 0.3981 nM
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