Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+)butaclamol
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 PubChem ID
CID: 37461
SID: 99459565
Canonical SMILES
CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34
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Compound Formula C25H31NO
Compound Structure
Protein Name
 Protein Info 
D(2) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P14416
Gene Name
DRD2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 0.37 nM
   TI
   LI
   LO
   TS
2
Ki = 2.58 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.4 nM
2 IC50 = 2.2 nM
3 IC50 = 8.7 nM
4 IC50 = 8.9 nM
5 IC50 = 12 nM
6 IC50 = 15 nM
7 Ki = 0.5 nM
8 Ki = 0.6 nM
9 Ki = 0.74 nM
10 Ki = 2.9 nM