| Compound ID |
Compound Name |
Compound Formula |
|
CP0427196
|
7-(5-methyl-3-isoxazolyl)-3-(3-{[4-methyl-5-(2-methyl-5-quinolinyl)-4H-1,2,4-triazol-3-yl]thio}propyl)-2,3,4,5-tetrahydro-1H-3-benzazepine
Show/Hide
|
C30H32N6OS
|
3
|
| 1 |
EC50 = 120 nM
|
|
|
| 2 |
IC50 = 125.89 nM
|
|
|
| 3 |
IC50 = 501.19 nM
|
|
|
|
CP0451174
|
US10207991, Ex. Cpd. No. 11
Show/Hide
|
C20H23Cl2NO2
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0189586
|
(2R)-4-(4-chlorophenyl)-N-[[4-(trifluoromethyl)phenyl]methyl]butan-2-amine
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|
C18H19ClF3N
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0534006
|
(2S)-4-(3,4-dichlorophenyl)-N-[[4-(trifluoromethyl)phenyl]methyl]butan-2-amine
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|
C18H18Cl2F3N
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0004712
|
(3S)-6-fluoro-3-[4-[4-(4-methylimidazol-1-yl)-3-(2,2,2-trifluoroethoxy)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C26H21F7N6O2
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0003449
|
(3S)-6-fluoro-3-[4-[2-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C25H22F4N6O2
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0415187
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2-methylsulfonyl-2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
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|
C25H29N5O3S2
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0481363
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2-pyrimidin-2-yl-2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
Show/Hide
|
C28H29N7OS
|
1
|
| 1 |
EC50 = 3350 nM
|
|
|
|
CP0561683
|
(2R)-4-(3,4-dichlorophenyl)-N-[[4-(trifluoromethyl)phenyl]methyl]butan-2-amine
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|
C18H18Cl2F3N
|
1
|
| 1 |
EC50 = 4400 nM
|
|
|
|
CP0417379
|
8-(5-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)pyridin-2-yl)-N-ethyl-2,8-diazaspiro[4.5]decane-2-carboxamide
Show/Hide
|
C27H32N6O2S
|
1
|
| 1 |
EC50 = 5000 nM
|
|
|
|
CP0463852
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-[2-(2-hydroxyethyl)-2,8-diazaspiro[4.5]decan-8-yl]pyridine-3-carboxamide
Show/Hide
|
C26H31N5O2S
|
1
|
| 1 |
EC50 = 6500 nM
|
|
|
|
CP0561641
|
US10207991, Ex. Cpd. No. 8
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|
C19H22FNO2
|
1
|
| 1 |
EC50 = 7000 nM
|
|
|
|
CP0004713
|
(3S)-6-fluoro-3-[4-[3-fluoro-2-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C25H21F5N6O2
|
1
|
| 1 |
EC50 = 7500 nM
|
|
|
|
CP0001151
|
(3S)-6-fluoro-3-[4-[4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C24H20F4N6O
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0003450
|
(3S)-6-fluoro-3-[4-[2-fluoro-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C24H19F5N6O
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0561643
|
US10207991, Ex. Cpd. No. 28
Show/Hide
|
C22H28FNO2
|
1
|
| 1 |
EC50 = 9600 nM
|
|
|
|
CP0064630
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
Show/Hide
|
C24H27N5OS
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0434686
|
6-(2-acetyl-2,7-diazaspiro[4.5]decan-7-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
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|
C26H29N5O2S
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0462589
|
6-(2-acetyl-2,7-diazaspiro[3.5]nonan-7-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
Show/Hide
|
C25H27N5O2S
|
1
|
| 1 |
EC50 = 10100 nM
|
|
|
|
CP0463851
|
6-(2-acetyl-2,8-diazaspiro[4.5]decan-8-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
Show/Hide
|
C26H29N5O2S
|
1
|
| 1 |
EC50 = 10100 nM
|
|
|
|
CP0415186
|
6-(7-acetyl-2,7-diazaspiro[4.4]nonan-2-yl)-N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
Show/Hide
|
C25H27N5O2S
|
1
|
| 1 |
EC50 = 10300 nM
|
|
|
|
CP0007180
|
(3S)-6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C25H22F4N6O2
|
1
|
| 1 |
EC50 = 13000 nM
|
|
|
|
CP0007807
|
(3S)-6-fluoro-3-[4-[3-methoxy-4-(3-methyl-1,2,4-triazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
Show/Hide
|
C24H21F4N7O2
|
1
|
| 1 |
EC50 = 15000 nM
|
|
|
|
CP0321380
|
4-[4-(1-acetylpiperidin-4-yl)phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
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|
C31H26F3NO3
|
1
|
| 1 |
EC50 = 16000 nM
|
|
|
|
CP0373424
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-(1-oxo-2,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
Show/Hide
|
C24H25N5O2S
|
1
|
| 1 |
EC50 = 18000 nM
|
|
|
|
CP0561645
|
US10207991, Ex. Cpd. No. 62
Show/Hide
|
C24H33NO4S
|
1
|
| 1 |
EC50 = 26000 nM
|
|
|
|
CP0494727
|
N-(2-amino-5-thiophen-2-ylphenyl)-6-(2-oxo-3-oxa-1,8-diazaspiro[4.5]decan-8-yl)pyridine-3-carboxamide
Show/Hide
|
C23H23N5O3S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0032210
|
4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
Show/Hide
|
C29H24F3NO2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0372898
|
4-(2-(4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-ylamino)piperidin-1-yl)ethyl)phenol
Show/Hide
|
C27H29FN4O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0046703
|
1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
Show/Hide
|
C24H26ClFN4O
|
3
|
| 1 |
IC50 = 2.7 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
| 3 |
IC50 = 10 nM
|
|
|
|
CP0371449
|
1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidine-2-thione
Show/Hide
|
C24H27FN4S
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0171480
|
(Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C24H27FN4O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0002229
|
(Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-phenyl)-ethyl]-methylamino}-ethoxy)-phenyl]-methanesulfonamide
Show/Hide
|
C19H27N3O5S2
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 630.96 nM
|
|
|
| 3 |
IC50 = 1460 nM
|
|
|
|
CP0198230
|
1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C24H24ClFN4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0425720
|
3-[3-[3-[[5-(3,4-dichlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H27Cl2N5OS
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0040184
|
1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-1,3-benzodiazol-2-amine
Show/Hide
|
C28H31FN4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0237326
|
N-[4-[4-[ethyl(heptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide
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|
C20H36N2O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0292876
|
1-[5-chloro-1-(4-fluorophenyl)indol-3-yl]-N,N-dimethylmethanamine
Show/Hide
|
C17H16ClFN2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0027419
|
1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C28H29F2N3O
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 50.12 nM
|
|
|
|
CP0058434
|
6-[[[1-[(1S)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C26H28FN5O5
|
2
|
| 1 |
IC50 = 18 nM
|
|
|
| 2 |
IC50 = 18000 nM
|
|
|
|
CP0372579
|
4-[4-methyl-5-[3-[7-(5-methyl-1,2-oxazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepin-3-yl]propylsulfanyl]-1,2,4-triazol-3-yl]benzonitrile
Show/Hide
|
C27H28N6OS
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0052474
|
(4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine-4-carbonyl}-phenyl)-methanesulfonamide
Show/Hide
|
C21H27N3O3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0298427
|
1-(2-{4-[1-(4-Fluoro-phenyl)-2,3-dihydro-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Show/Hide
|
C24H29FN4O
|
1
|
| 1 |
IC50 = 23.5 nM
|
|
|
|
CP0427205
|
3-[3-[3-[[5-(4-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28ClN5OS
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0461488
|
5-methyl-3-[3-[3-[[4-methyl-5-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C27H31N5OS
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0204754
|
1-(4-fluorobenzyl)-N-(piperidin-4-yl)-1H-benzo[d]imidazol-2-amine
Show/Hide
|
C19H21FN4
|
1
|
| 1 |
IC50 = 28.18 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
3
|
| 1 |
IC50 = 30.2 nM
|
|
|
| 2 |
IC50 = 32 nM
|
|
|
| 3 |
IC50 = 1100 nM
|
|
|
|
CP0464550
|
7-(2,5-dimethylpyrazol-3-yl)-3-[3-[[4-methyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C28H31F3N6S
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0040196
|
1-(1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C22H22FN3O2
|
1
|
| 1 |
IC50 = 32.36 nM
|
|
|
|
CP0311464
|
N-[1'-(6-cyano-1,2,3,4-tetrahydronaphthalen-2-yl)-4-hydroxyspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl]methanesulfonamide
Show/Hide
|
C25H29N3O4S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0306020
|
4-(5-Chloro-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-piperidin-4-yl}-indol-1-yl)-benzoic acid methyl ester
Show/Hide
|
C26H29ClN4O3
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0942199
|
2-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)ethanol
Show/Hide
|
C23H24F3N5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0064169
|
5-hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-(piperidin-1-ylmethyl)-1-benzofuran-3-carboxamide
Show/Hide
|
C22H24N2O4
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0372585
|
3-[3-[3-[[5-(2-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0379000
|
3-[3-[3-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C27H31N5O2S
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0404764
|
2-[3-[3-[[5-(1H-indol-5-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,3-oxazole
Show/Hide
|
C28H30N6OS
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0030226
|
4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide
Show/Hide
|
C23H29ClFN3O4
|
4
|
| 1 |
IC50 = 39.81 nM
|
|
|
| 2 |
IC50 = 45 nM
|
|
|
| 3 |
IC50 = 80 nM
|
|
|
| 4 |
IC50 = 98 nM
|
|
|
|
CP0240967
|
3-(4-Methylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinoline
Show/Hide
|
C22H22F3N5O2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0427207
|
2-[3-[3-[[5-(1H-indol-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,3-oxazole
Show/Hide
|
C28H30N6OS
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0033565
|
(+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol
Show/Hide
|
C32H41NO2
|
2
|
| 1 |
IC50 = 56 nM
|
|
|
| 2 |
IC50 = 199.53 nM
|
|
|
|
CP0163218
|
4-amino-5-chloro-N-[(3R,4S)-1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
Show/Hide
|
C23H29ClFN3O4
|
3
|
| 1 |
IC50 = 56 nM
|
|
|
| 2 |
IC50 = 190 nM
|
|
|
| 3 |
IC50 = 25000 nM
|
|
|
|
CP0404759
|
5-methyl-3-[3-[3-[[4-methyl-5-[4-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C27H28F3N5OS
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0465251
|
3-[3-[3-[[5-(2-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28ClN5OS
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0466839
|
3-[3-[3-[[5-(3-chlorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28ClN5OS
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0536676
|
3-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]naphthalen-2-ol
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0237321
|
1-{2-[4-(5-Chloro-1-phenyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-imidazolidin-2-one
Show/Hide
|
C24H27ClN4O
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0648622
|
N-(4-(1-(2-(6-methylpyridin-2-yl)ethyl)piperidine-4-carbonyl)phenyl)methanesulfonamide dihydrochloride
Show/Hide
|
C21H29Cl2N3O3S
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0135724
|
N-[1-[(3-ethoxy-4-methoxyphenyl)methyl]piperidin-4-yl]-1,3-benzoxazol-2-amine
Show/Hide
|
C22H27N3O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0542610
|
4-benzyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0709801
|
N-(benzo[c][1,2,5]oxadiazol-4-ylmethyl)-3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinolin-5-amine
Show/Hide
|
C22H21F3N6O
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0421328
|
6-(1-benzothiophen-2-yl)-N-methyl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine
Show/Hide
|
C22H28N4S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0056386
|
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one
Show/Hide
|
C21H21ClN4OS
|
1
|
| 1 |
IC50 = 120.23 nM
|
|
|
|
CP0427206
|
5-methyl-3-[3-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C24H27N5OS2
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0466797
|
5-methyl-3-[3-[3-[[4-methyl-5-(4-methylcyclohexyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C27H37N5OS
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0477527
|
N-[4-(1-phenylpyrrolo[2,3-c]pyridin-3-yl)pyridin-2-yl]cyclopropanecarboxamide
Show/Hide
|
C22H18N4O
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0297101
|
methyl 2-[4-[5-chloro-3-[1-[2-(2-oxoimidazolidin-1-yl)ethyl]piperidin-4-yl]indol-1-yl]phenyl]acetate
Show/Hide
|
C27H31ClN4O3
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0334084
|
1-{2-[4-(5-Chloro-1-cyclohexyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-imidazolidin-2-one
Show/Hide
|
C24H33ClN4O
|
1
|
| 1 |
IC50 = 137 nM
|
|
|
|
CP0036382
|
CAS_52-53-9
Show/Hide
|
C27H38N2O4
|
3
|
| 1 |
IC50 = 141.25 nM
|
|
|
| 2 |
IC50 = 143 nM
|
|
|
| 3 |
IC50 = 530 nM
|
|
|
|
CP0039958
|
(risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O2
|
1
|
| 1 |
IC50 = 151.36 nM
|
|
|
|
CP0465216
|
3-[3-[3-[[5-(6-methoxypyridin-3-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H30N6O2S
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0007317
|
(+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol
Show/Hide
|
C22H31NO
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0715131
|
[2H]-2-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)ethanol
Show/Hide
|
C23H24F3N5O3
|
1
|
| 1 |
IC50 = 160 nM
|
|
|
|
CP0068895
|
ethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate
Show/Hide
|
C22H23ClN2O2
|
1
|
| 1 |
IC50 = 169.82 nM
|
|
|
|
CP0672402
|
3-((3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinolin-5-ylamino)methyl)benzonitrile
Show/Hide
|
C23H22F3N5
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
|
CP0063599
|
N-[1-[(3-ethoxy-4-methoxyphenyl)methyl]piperidin-4-yl]-5-ethylsulfonyl-1,3-benzoxazol-2-amine
Show/Hide
|
C24H31N3O5S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0045063
|
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
Show/Hide
|
C17H20N4S
|
1
|
| 1 |
IC50 = 181.97 nM
|
|
|
|
CP0104272
|
1-[1,3-bis(chloranyl)-6-(trifluoromethyl)phenanthren-9-yl]-3-(dibutylamino)propan-1-ol;hydrochloride
Show/Hide
|
C26H30Cl2F3NO
|
2
|
| 1 |
IC50 = 196 nM
|
|
|
| 2 |
IC50 = 199.53 nM
|
|
|
|
CP0327634
|
1-(2-Chroman-4-yl-ethyl)-4-(3,4-dimethoxy-phenyl)-piperidine
Show/Hide
|
C24H31NO3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0568262
|
US9315520, Comparator 7
Show/Hide
|
C20H20ClFN4O2S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0689610
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(3-fluoro-4-trifluoromethylphenyl)prop2-en-1-amine Hydrochloride
Show/Hide
|
C21H22ClF4NO
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0714365
|
SID50107178
Show/Hide
|
C27H39ClN2O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0486292
|
2-methyl-4,9-bis(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C25H32N2O2
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0110939
|
5-Chloro-1-(4-fluoro-phenyl)-3-piperidin-4-yl-1H-indole
Show/Hide
|
C19H18ClFN2
|
1
|
| 1 |
IC50 = 204 nM
|
|
|
|
CP0659845
|
N-ethyl-4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazine-1-carboxamide
Show/Hide
|
C24H25F3N6O3
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0567561
|
5-pyrazol-1-yl-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]phenol
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0372576
|
3-[3-[3-[[5-(3-fluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C26H28FN5OS
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0378819
|
3-[3-[[5-(3,4-difluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-7-(2,5-dimethylpyrazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C27H30F2N6S
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0404758
|
5-methyl-3-[3-[3-[(4-methyl-5-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C25H28N6OS
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0404763
|
5-methyl-3-[3-[3-[[4-methyl-5-(1-methylpyrrol-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C25H30N6OS
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0264620
|
(S)-1-(2-(chroman-4-yl)ethyl)-4-(3,4-dimethoxyphenyl)piperidine
Show/Hide
|
C24H31NO3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0520709
|
US8975247, EBP661
Show/Hide
|
C23H28ClN3
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0720028
|
(+)-((1S,2S)-2-(2-(allyloxy)-5-chlorophenyl)cyclopropyl)methanamine trifluoroacetate
Show/Hide
|
C15H17ClF3NO3
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0572678
|
2-[6-(2,9-diazaspiro[4.5]decan-2-yl)pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol
Show/Hide
|
C21H24N6O
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0256763
|
2,6-dichloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
Show/Hide
|
C23H31Cl2N5O3S
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0485875
|
2-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-5-pyrazol-1-ylphenol
Show/Hide
|
C23H30N6O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0536677
|
3-hydroxy-4-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]benzonitrile
Show/Hide
|
C21H27N5O
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0372584
|
5-methyl-2-[3-[3-[(4-methyl-5-thiophen-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,3-oxazole
Show/Hide
|
C24H27N5OS2
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0404762
|
5-methyl-3-[3-[3-[[4-methyl-5-(trifluoromethyl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C21H24F3N5OS
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0426969
|
3-[3-[3-[[5-(2,3-dimethylquinoxalin-6-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C30H33N7OS
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0440995
|
4-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-N-methyl-N-(4-methylphenyl)sulfonylpiperidine-1-carboxamide
Show/Hide
|
C25H31Cl2N3O4S
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
IC50 = 323.59 nM
|
|
|
|
CP0034615
|
(6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
IC50 = 323.59 nM
|
|
|
|
CP0294516
|
10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine
Show/Hide
|
C21H26N2OS2
|
1
|
| 1 |
IC50 = 323.59 nM
|
|
|
|
CP0400471
|
US9266876, 80
Show/Hide
|
C23H21BrN8OS
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0035893
|
(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine
Show/Hide
|
C21H26N2S2
|
1
|
| 1 |
IC50 = 363.08 nM
|
|
|
|
CP0565786
|
US9266876, 73
Show/Hide
|
C26H26N8OS
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0894307
|
morpholino(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)methanone
Show/Hide
|
C26H27F3N6O4
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0465250
|
3-[3-[3-[(5-tert-butyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C24H33N5OS
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0097168
|
US9315520, Comparator 2
Show/Hide
|
C20H20F3N5O3S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0435812
|
2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0429608
|
ACP-103
Show/Hide
|
C25H34FN3O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0269624
|
2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylamino)benzo[d]oxazole-5-carboxamide
Show/Hide
|
C24H29FN4O4
|
1
|
| 1 |
IC50 = 430 nM
|
|
|
|
CP0146498
|
2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one
Show/Hide
|
C24H25FN6O
|
1
|
| 1 |
IC50 = 436.52 nM
|
|
|
|
CP0557041
|
6-[4-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]butoxy]-2-methyl-4H-1,4-benzoxazin-3-one
Show/Hide
|
C30H35N3O4
|
1
|
| 1 |
IC50 = 448 nM
|
|
|
|
CP0313890
|
4-[4-(Hydroxy-diphenyl-methyl)-piperidin-1-yl]-1-[4-(1-hydroxy-1-methyl-ethyl)-phenyl]-butan-1-ol
Show/Hide
|
C31H39NO3
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0135801
|
3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinoline
Show/Hide
|
C23H22F3N5O3
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0742393
|
[2H]-2-(4-(5-([2H]-3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)ethanol
Show/Hide
|
C23H24F3N5O3
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0474090
|
2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethoxy)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C25H25ClF3N3O3
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0531767
|
US8975247, EBP660
Show/Hide
|
C22H26ClN3
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0315809
|
7-fluoro-3-(4-methoxyphenyl)-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
|
C25H19FN4O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0423817
|
US9315520, Comparator 4
Show/Hide
|
C20H19F3N4O3S
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0372582
|
3-[2-[[5-(3,4-difluorophenyl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]ethyl]-7-(2,5-dimethylpyrazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C26H28F2N6S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0505483
|
5-methyl-2-[3-[3-[[4-methyl-5-(1-methylpyrrol-2-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,3-oxazole
Show/Hide
|
C25H30N6OS
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0576107
|
5-cyclopentyl-17-hydroxy-7,12,20-trioxa-5-azapentacyclo[11.8.0.02,11.03,8.014,19]henicosa-1(13),2(11),3(8),9,14(19),15,17-heptaen-21-one
Show/Hide
|
C22H19NO5
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0278751
|
BEPRIDIL HYDROCHLORIDE
Show/Hide
|
C24H34N2O
|
1
|
| 1 |
IC50 = 549.54 nM
|
|
|
|
CP0720695
|
Azimilide
Show/Hide
|
C23H28ClN5O3
|
2
|
| 1 |
IC50 = 560 nM
|
|
|
| 2 |
IC50 = 1412.54 nM
|
|
|
|
CP0421443
|
2-(3-chlorophenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamide
Show/Hide
|
C25H25ClF3N3O2
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0546732
|
1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-pyrrolo[3,2-c]pyridin-1-ylethanone
Show/Hide
|
C24H24F3N7O2S
|
1
|
| 1 |
IC50 = 570 nM
|
|
|
|
CP0170290
|
2-[4-[5-chloro-3-[1-[2-(2-oxoimidazolidin-1-yl)ethyl]piperidin-4-yl]indol-1-yl]phenyl]acetic acid
Show/Hide
|
C26H29ClN4O3
|
1
|
| 1 |
IC50 = 579 nM
|
|
|
|
CP0556605
|
US8975247, EBP881
Show/Hide
|
C23H28ClN3
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0968184
|
N-ethyl-N-(2-fluoro-5-(3-(4-(methylsulfinyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)benzyl)ethanamine
Show/Hide
|
C24H25FN4OS
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0396847
|
4-(1-phenylpyrrolo[2,3-c]pyridin-3-yl)pyridin-2-amine
Show/Hide
|
C18H14N4
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0048052
|
4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorobenzonitrile
Show/Hide
|
C23H24FN3O4S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0400687
|
N-[2-[(2S,6R)-2,6-dimethylpiperidin-1-yl]ethyl]-1-[(4-fluorophenyl)methyl]triazol-4-amine
Show/Hide
|
C18H26FN5
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0183196
|
6-[[[1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C26H28FN5O4
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0421329
|
6-(1-benzothiophen-2-yl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine
Show/Hide
|
C21H26N4S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0526449
|
4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]-N-pyrimidin-4-ylpyrimidin-2-amine
Show/Hide
|
C22H20FN7S
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0563709
|
US10266537, Compound 31
Show/Hide
|
C28H26F3N7O
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0407598
|
N-[(4-fluorophenyl)methyl]-N-(3-hydroxypropyl)-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C29H33F4N3O2
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0526109
|
US9266876, 47
Show/Hide
|
C23H22N8OS
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0013001
|
(+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0535903
|
US8975247, EBP425
Show/Hide
|
C20H22ClN3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0553258
|
N-[3-[2-[4-amino-1-[(3R)-1-methylpyrrolidin-3-yl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C27H24F3N7O
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0452144
|
3-Fluoro-4-[4-(2-isobutoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzonitrile
Show/Hide
|
C23H26FN3O4S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0051344
|
(S)-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)-3-methylbenzoic acid
Show/Hide
|
C29H26ClF2N3O3
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0456826
|
4-N-(oxan-4-yl)-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H17F3N4OS
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0530506
|
6-[[[1-[2-[6-methoxy-3-(trifluoromethyl)-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C27H28F3N5O4
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0343389
|
4-cyano-N-[(1R)-1-[(1S,5R)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
|
C23H20F2N4O
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0477961
|
US9266876, 49
Show/Hide
|
C24H24N8OS
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0372578
|
5-methyl-3-[3-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C25H28N6OS
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0372589
|
3-[3-[3-[(5-cyclopentyl-4-methyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C25H33N5OS
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0379040
|
3-[3-[3-[(4,5-dimethyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-5-methyl-1,2-oxazole
Show/Hide
|
C21H27N5OS
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0405809
|
5-methyl-2-[3-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,3-oxazole
Show/Hide
|
C30H32N6OS
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0067406
|
3-(4-fluorophenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
|
C22H19F4N3O3
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0457715
|
(R)-5-(4-chlorophenyl)-N-(1-(4-(3-(4-(cyclopropanecarbonyl)phenoxy)propyl)piperazin-1-yl)-1-oxopropan-2-yl)furan-2-carboxamide
Show/Hide
|
C31H34ClN3O5
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0491749
|
N-[bis(4-fluorophenyl)methyl]-2-[1-[[1-[5-(trifluoromethyl)pyridin-2-yl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H29F5N4O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0506346
|
N-[bis(4-fluorophenyl)methyl]-2-[4-[[1-[5-(trifluoromethyl)pyridin-2-yl]pyrrol-3-yl]methyl]piperazin-1-yl]acetamide
Show/Hide
|
C30H28F5N5O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0000082
|
CAS_68647
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
IC50 = 812.83 nM
|
|
|
|
CP0374821
|
4-N-piperidin-4-yl-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H18F3N5S
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0567101
|
N-[4-(4-methylpiperazin-1-yl)phenyl]-6-[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]pyrimidine-4-carboxamide
Show/Hide
|
C25H27F3N6O
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0563821
|
N-[(3S,4S)-1-cyclohexyl-3-(2-pyridin-2-ylethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C29H33F2N5O3
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0526126
|
US9266876, 146
Show/Hide
|
C25H26N8OS
|
1
|
| 1 |
IC50 = 960 nM
|
|
|
|
CP0531766
|
US8975247, EBP470
Show/Hide
|
C23H26ClN3
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0247101
|
3-(1H-indol-3-yl)-N-methyl-3-phenylpropan-1-amine
Show/Hide
|
C18H20N2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0456059
|
N-[1-(6-methoxypyridin-3-yl)pentyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C30H37F3N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0124785
|
8-(1H-benzimidazol-2-yl)-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0416262
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5-methyl-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C20H29N7O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0032520
|
4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]-N-(2-methylpyridin-4-yl)pyrimidin-2-amine
Show/Hide
|
C24H23FN6S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0407599
|
2-(1-((5-(4-chlorophenyl)furan-2-yl)methyl)piperidin-4-yl)-N-(3,3,3-trifluoro-2-hydroxypropyl)acetamide
Show/Hide
|
C21H24ClF3N2O3
|
1
|
| 1 |
IC50 = 1020 nM
|
|
|
|
CP0366397
|
6-[[[1-[2-(6-methoxy-3-methyl-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C27H31N5O4
|
1
|
| 1 |
IC50 = 1060 nM
|
|
|
|
CP0398983
|
2-(1-((5-(4-chlorophenyl)furan-2-yl)methyl)piperidin-4-yl)-N-(4-fluorobenzyl)-N-(2-hydroxy-3-methoxypropyl)acetamide
Show/Hide
|
C29H34ClFN2O4
|
1
|
| 1 |
IC50 = 1090 nM
|
|
|
|
CP0087489
|
6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C22H25N3O4
|
1
|
| 1 |
IC50 = 1096.48 nM
|
|
|
|
CP0435587
|
3-methyl-4-[2-[(3-pyridin-2-yl-1H-pyrazol-5-yl)methylamino]pyridin-4-yl]benzonitrile
Show/Hide
|
C22H18N6
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0400620
|
US8975247, EBP467
Show/Hide
|
C22H26ClN3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0556602
|
US8975247, EBP933
Show/Hide
|
C27H31BrClN3
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0547955
|
4-chloro-N-[(1R)-1-[(1R,5S)-3-(6-fluoro-2-methylbenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C24H25ClFN3O
|
2
|
| 1 |
IC50 = 1100 nM
|
|
|
| 2 |
IC50 = 21000 nM
|
|
|
|
CP0543621
|
1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2,2,2-trifluoroethoxy)phenyl]methyl]urea
Show/Hide
|
C22H26F4N4O2
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0015196
|
2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-(2-methylsulfonylethyl)-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
|
C22H22FN3O5S
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0461046
|
1-(3-fluorobenzyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C25H26F4N4O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0425944
|
4-[4-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C22H22F3N3O4S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0349959
|
1-cyclopropyl-3-[4-(1-phenylpyrrolo[2,3-c]pyridin-3-yl)pyridin-2-yl]urea
Show/Hide
|
C22H19N5O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0403664
|
3-(3,4-dimethoxyphenyl)-5-N-(1,2,2,6,6-pentamethylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Show/Hide
|
C30H38N6O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0572665
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(3-fluorophenyl)propanamide
Show/Hide
|
C24H30FN3O
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0427208
|
7-(2,5-dimethylpyrazol-3-yl)-3-[4-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]butan-2-yl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C32H37N7S
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0440408
|
5-methyl-3-[3-[3-[(4-methyl-5-propan-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C23H31N5OS
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0366411
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(6-tert-butylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C20H29N7O
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0010656
|
3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0780081
|
3-(4-methylpiperazin-1-yl)-N-([2H]-3-nitrobenzyl)-7-(trifluoromethyl)quinolin-5-amine
Show/Hide
|
C22H22F3N5O2
|
1
|
| 1 |
IC50 = 1270 nM
|
|
|
|
CP0732198
|
(S)-2-amino-1-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)propan-1-one
Show/Hide
|
C24H25F3N6O3
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0732199
|
4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)-N-propylpiperazine-1-carboxamide
Show/Hide
|
C25H27F3N6O3
|
1
|
| 1 |
IC50 = 1280 nM
|
|
|
|
CP0003286
|
N-[5-(3-fluorophenyl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutanamide
Show/Hide
|
C18H23FN4O
|
1
|
| 1 |
IC50 = 1290 nM
|
|
|
|
CP0081578
|
4-(4-fluoro-phenyl)-8-[1-(4-fluoro-phenyl)-cyclohexyl]-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C26H30F2N2O
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0192349
|
1-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide
Show/Hide
|
C31H32F3N5O
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0035744
|
1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl)urea
Show/Hide
|
C21H27FN4O
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0279273
|
N-[3-[(1R)-3-amino-1-(1-ethyl-5-methyl-6-oxopyridin-3-yl)-4-fluoroisoindol-1-yl]phenyl]-5-chloropyridine-2-carboxamide
Show/Hide
|
C28H23ClFN5O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0177352
|
6-[[[1-[2-(6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C26H29N5O4
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0564949
|
US8975247, EBP271
Show/Hide
|
C22H25ClN2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0689612
|
(E)-N-(Coumaran-5-methyl)-N-methyl-3-(4-difluoromethylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C20H22ClF2NO
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0526110
|
US9266876, 50
Show/Hide
|
C26H28N8OS
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0031250
|
N-[5-[5-[2-(cyclopropylmethylamino)pyrimidin-4-yl]-2-(1-methylpiperidin-4-yl)-1,3-thiazol-4-yl]-2-fluorophenyl]methanesulfonamide
Show/Hide
|
C24H29FN6O2S2
|
1
|
| 1 |
IC50 = 1340 nM
|
|
|
|
CP0055808
|
3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
IC50 = 1380.38 nM
|
|
|
|
CP0039737
|
5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carbonitrile
Show/Hide
|
C20H19N3
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0054458
|
(S)-2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-N,2-dicyclohexylacetamide
Show/Hide
|
C27H30ClF2N3O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0456825
|
2-N-methyl-4-N-(2-piperazin-1-ylethyl)-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C20H23F3N6S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0690827
|
1-[1-(2-methylpropanesulfonyl)-4-[4-(trifluoromethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-6-yl]piperazine
Show/Hide
|
C22H25F3N4O2S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0190228
|
(E)-N-methyl-N-(5,6,7,8-tetrahydronaphthalen-2-ylmethyl)-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-amine;hydrochloride
Show/Hide
|
C22H25ClF3N
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0537080
|
N-[(3S,4S)-1-(cyclobutylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C28H30F2N6O3
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0176864
|
CHEMBL4853672
Show/Hide
|
C24H22F2N4O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0013607
|
2-methoxyacetic acid [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methyl-amino]ethyl]-6-fluoro-1-isopropyl-tetralin-2-yl] ester;hydrate;hydrochloride
Show/Hide
|
C29H38FN3O3
|
2
|
| 1 |
IC50 = 1445.44 nM
|
|
|
| 2 |
IC50 = 3300 nM
|
|
|
|
CP0033479
|
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
Show/Hide
|
C17H19ClN2S
|
2
|
| 1 |
IC50 = 1470 nM
|
|
|
| 2 |
IC50 = 1479.11 nM
|
|
|
|
CP0351171
|
5-Chloro-3-(1-ethyl-propyl)-1-(4-fluoro-phenyl)-1H-indole
Show/Hide
|
C19H19ClFN
|
1
|
| 1 |
IC50 = 1480 nM
|
|
|
|
CP0455515
|
2-amino-1-[2-(4-fluorophenyl)-3-(4-methylanilino)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
|
C23H26FN5O
|
1
|
| 1 |
IC50 = 1500 nM
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CP0347512
|
6-(4-methoxyphenyl)-2-methyl-6-(3-pyrimidin-5-ylphenyl)pyrrolo[3,4-d][1,3]thiazol-4-amine
Show/Hide
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C23H19N5OS
|
1
|
| 1 |
IC50 = 1500 nM
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CP0490679
|
6-naphthalen-2-yl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine
Show/Hide
|
C23H28N4
|
1
|
| 1 |
IC50 = 1500 nM
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CP0527921
|
4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]-N-(pyridin-4-ylmethyl)pyrimidin-2-amine
Show/Hide
|
C24H23FN6S
|
1
|
| 1 |
IC50 = 1500 nM
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CP0556675
|
N-(2,6-dimethylpyridin-4-yl)-4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]pyrimidin-2-amine
Show/Hide
|
C25H25FN6S
|
1
|
| 1 |
IC50 = 1500 nM
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CP0426236
|
(2R)-4-ethyl-9-[2-(4-fluorophenyl)ethyl]-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C19H27FN2O2
|
1
|
| 1 |
IC50 = 1500 nM
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CP0444871
|
N-(1-cyclohexylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C21H25F2N3O2
|
1
|
| 1 |
IC50 = 1500 nM
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|
|
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CP0517204
|
N-[(3S,4S)-1-cyclohexyl-3-(2-pyridin-2-ylpropan-2-ylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C30H35F2N5O3
|
1
|
| 1 |
IC50 = 1500 nM
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|
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CP0035258
|
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Show/Hide
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C17H18F3NO
|
1
|
| 1 |
IC50 = 1513.56 nM
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CP0118632
|
N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclopentanecarboxamide
Show/Hide
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C26H39N5OS
|
1
|
| 1 |
IC50 = 1520 nM
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|
|
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CP0495572
|
N-[(4-chloro-2-hydroxyphenyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
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C25H25ClF3N3O2
|
1
|
| 1 |
IC50 = 1550 nM
|
|
|
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CP0506083
|
N-[(2-chloro-4-hydroxyphenyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C25H25ClF3N3O2
|
1
|
| 1 |
IC50 = 1550 nM
|
|
|
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CP0195878
|
2-[3-(4-fluorophenyl)-2-oxo-1-oxa-3-azaspiro[4.5]decan-8-yl]-3H-benzimidazole-5-carbonitrile
Show/Hide
|
C22H19FN4O2
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
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CP0476232
|
N-[(1S,2S)-1-[3-(2-methoxyethylamino)propanoylamino]-2,3-dihydro-1H-inden-2-yl]-1-methylindole-2-carboxamide
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
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CP0407597
|
N-[(2,4-dichlorophenyl)methyl]-4-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperazine-1-carboxamide
Show/Hide
|
C24H23Cl2F3N4O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0054413
|
(S)-2-(6-chloro-2-(4-chlorophenyl)-5-fluoro-1H-benzo[d]imidazol-1-yl)-N,2-dicyclohexylacetamide
Show/Hide
|
C27H30Cl2FN3O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
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CP0239466
|
6-chloro-2,4-dimethyl-N-[(3R)-3-[4-[methylcarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C24H34ClN5O2S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0315810
|
7-fluoro-3-[3-(5-fluoropyridin-3-yl)phenyl]-3-pyridin-4-ylisoindol-1-amine
Show/Hide
|
C24H16F2N4
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0241751
|
4-amino-N-[(4-chlorophenyl)-phenylmethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C25H25ClN6O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0066337
|
N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide
Show/Hide
|
C31H33ClN2O3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0282371
|
2-[4-[2-(tert-butylcarbamoylamino)ethyl]piperazin-1-yl]-N-(3,5-dichlorophenyl)acetamide
Show/Hide
|
C19H29Cl2N5O2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0105032
|
2-ethyl-2-(3-pyrimidin-5-ylphenyl)-1,3-benzoxazin-4-amine
Show/Hide
|
C20H18N4O
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0187394
|
(4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(3-methyl-1,2-oxazol-5-yl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
|
C17H17F2N3O2S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0529247
|
US8975247, EBP372
Show/Hide
|
C22H24ClN3
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0535161
|
N-[(4-chlorophenyl)-pyridin-4-ylmethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H30ClF3N4O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0046190
|
5-[3-[3-amino-4-fluoro-1-[2-(trifluoromethyl)pyridin-4-yl]isoindol-1-yl]phenyl]pyridine-3-carbonitrile
Show/Hide
|
C26H15F4N5
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0518475
|
1-(3,4-dichlorophenyl)-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C15H19Cl2N5
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0119048
|
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine
Show/Hide
|
C17H26ClNO
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0471501
|
2-(pyridin-3-ylmethyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C28H32F3N5O
|
1
|
| 1 |
IC50 = 1730 nM
|
|
|
|
CP0506350
|
N-[(4-fluorophenyl)-(6-methoxypyridin-3-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C32H32F4N4O2
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0177353
|
6-[[[1-[2-[3-(difluoromethyl)-6-methoxy-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C27H29F2N5O4
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0259576
|
oxalic acid;1-[5-(4-phenylphenoxy)pentyl]piperidine
Show/Hide
|
C24H31NO5
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0546731
|
US9266876, 51
Show/Hide
|
C24H21F3N8OS
|
1
|
| 1 |
IC50 = 1750 nM
|
|
|
|
CP0467252
|
4-N-[3-(dimethylamino)propyl]-2-N-methyl-6-(4-morpholin-4-ylphenyl)thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C22H30N6OS
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0556928
|
US9315520, Comparator 5
Show/Hide
|
C19H19N5O2S2
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
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CP0015258
|
6-[(1,1-dioxothiolan-2-yl)methyl]-2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
|
C24H24FN3O5S
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0506011
|
2-(4-fluorophenyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C28H30F4N4O
|
1
|
| 1 |
IC50 = 1810 nM
|
|
|
|
CP0486336
|
(2R)-1-(4-imidazo[1,2-a]pyridin-2-ylphenoxy)-3-[4-[2-(4-methoxyphenyl)phenyl]piperidin-1-yl]propan-2-ol
Show/Hide
|
C34H35N3O3
|
1
|
| 1 |
IC50 = 1863 nM
|
|
|
|
CP0482070
|
4-[3-[4-(5-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0453353
|
3-methyl-4-[2-(2H-pyrazolo[3,4-b]pyridin-3-ylmethylamino)pyridin-4-yl]benzonitrile
Show/Hide
|
C20H16N6
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0258690
|
N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-5-amine
Show/Hide
|
C20H22F3N5O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
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CP0756577
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(4-difluoromethylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C21H24ClF2NO
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0842644
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(4-bromorphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C20H23BrClNO
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0005212
|
US8987315, Ketoconazole
Show/Hide
|
C26H28Cl2N4O4
|
1
|
| 1 |
IC50 = 1905.46 nM
|
|
|
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CP0953124
|
N-(2-{7-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)propane-2-sulfonamide
Show/Hide
|
C21H32N4O5S
|
1
|
| 1 |
IC50 = 1905.46 nM
|
|
|
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CP0511767
|
(2R)-1-(4-imidazo[1,2-a]pyridin-2-ylphenoxy)-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]propan-2-ol
Show/Hide
|
C33H34N4O3
|
1
|
| 1 |
IC50 = 1907 nM
|
|
|
|
CP0232871
|
1-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-propan-1-one
Show/Hide
|
C17H13ClFNO
|
1
|
| 1 |
IC50 = 1947 nM
|
|
|
|
CP0043968
|
7-(2,5-dimethylpyrazol-3-yl)-3-[3-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C31H35N7S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0200768
|
N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide
Show/Hide
|
C28H30N4O
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
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CP0372583
|
5-methyl-3-[3-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
|
C26H29N5OS
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0399508
|
7-(2,5-dimethylpyrazol-3-yl)-3-[2-[[4-methyl-5-(2-methylquinolin-5-yl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C30H33N7S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0426962
|
7-(2,5-dimethylpyrazol-3-yl)-3-[2-[[4-methyl-5-(5-methylpyrazin-2-yl)-1,2,4-triazol-3-yl]sulfanyl]ethyl]-1,2,4,5-tetrahydro-3-benzazepine
Show/Hide
|
C25H30N8S
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
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CP0067425
|
3-phenyl-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C21H19F3N4O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0105440
|
CHEMBL1289609
Show/Hide
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C22H21F3N4O3
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
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CP0116427
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5-methoxy-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C20H29N7O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
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CP0452145
|
3-Fluoro-4-{4-[5-methanesulfonyl-2-(2,2,2-trifluoro-ethoxy)-benzoyl]-piperazin-1-yl}-benzonitrile
Show/Hide
|
C21H19F4N3O4S
|
1
|
| 1 |
IC50 = 2000 nM
|
|
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CP0380870
|
6-(2,1,3-benzoxadiazol-5-yl)-4-N-[3-(dimethylamino)propyl]-2-N-methylthieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H21N7OS
|
1
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| 1 |
IC50 = 2000 nM
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|
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CP0724214
|
(+)-((1S,2S)-2-(5-chloro-2-(2-fluoroethoxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
|
C12H16Cl2FNO
|
1
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| 1 |
IC50 = 2000 nM
|
|
|
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CP0567161
|
6-[[[1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-8-methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C27H30FN5O4
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
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CP0485355
|
3-(4-methoxyphenoxy)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)azetidine-1-carboxamide
Show/Hide
|
C28H31F3N4O3
|
1
|
| 1 |
IC50 = 2030 nM
|
|
|
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CP0343761
|
oxalic acid;1-[5-(4-phenylphenoxy)pentyl]azepane
Show/Hide
|
C25H33NO5
|
1
|
| 1 |
IC50 = 2030 nM
|
|
|
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CP0097120
|
N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclohexanecarboxamide
Show/Hide
|
C27H41N5OS
|
1
|
| 1 |
IC50 = 2060 nM
|
|
|
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CP0730899
|
5-(4-chlorophenyl)-N-(3-methylphenyl)furan-2-carboxamidine hydrochloride
Show/Hide
|
C18H16Cl2N2O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0462008
|
OXIPEROMIDE
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
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CP0257263
|
5-[3-amino-4-fluoro-1-(3-pyrimidin-5-ylphenyl)isoindol-1-yl]-2-methoxy-3-methylbenzonitrile
Show/Hide
|
C27H20FN5O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0123096
|
US8865706, 9
Show/Hide
|
C18H19F2N3O2S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
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CP0121807
|
6-(4-methylpiperazin-1-yl)-1-(2-methylpropylsulfonyl)-4-[4-(trifluoromethyl)phenyl]pyrrolo[2,3-b]pyridine
Show/Hide
|
C23H27F3N4O2S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
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CP0108306
|
2-phenyl-4-[2-phenylethyl-[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C27H28N4OS
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0444610
|
CHEMBL4870418
Show/Hide
|
C24H23ClN4O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0404742
|
1-((1-hydroxycyclohexyl)methyl)-1-methyl-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C26H35F3N4O2
|
1
|
| 1 |
IC50 = 2160 nM
|
|
|
|
CP0407596
|
N-[(4-fluorophenyl)-pyridin-3-ylmethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H30F4N4O
|
1
|
| 1 |
IC50 = 2170 nM
|
|
|
|
CP0237325
|
1-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-propan-1-ol
Show/Hide
|
C17H15ClFNO
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0169653
|
7-fluoro-3-(2-methoxypyridin-4-yl)-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
|
C24H18FN5O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
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CP0398164
|
1-[(3,4-dichlorophenyl)methyl]-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C16H21Cl2N5
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
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CP0472333
|
1-(3,4-difluorophenyl)-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C15H19F2N5
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0962515
|
(E)-N-(Coumaran-5-methyl)-N-methyl-3-(4-trifluoromethylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C20H21ClF3NO
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0559087
|
5-fluoro-2-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]phenol
Show/Hide
|
C20H27FN4O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0549549
|
N-[[4-(4-butylpiperazin-1-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C23H35F3N4O2
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1
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| 1 |
IC50 = 2200 nM
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CP0517372
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US9266876, 17
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C23H22N8OS
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1
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| 1 |
IC50 = 2200 nM
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CP0569956
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3-[2-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-oxoethyl]-1,3-benzoxazol-2-one
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C24H23F3N6O4S
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1
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| 1 |
IC50 = 2200 nM
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CP0535160
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N-[phenyl(pyridin-2-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
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C31H31F3N4O
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1
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| 1 |
IC50 = 2300 nM
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CP0501680
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2-amino-1-[3-(4-chloroanilino)-2-(4-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
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C22H23ClFN5O
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1
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| 1 |
IC50 = 2300 nM
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CP0123101
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(4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(4-methyl-1,3-oxazol-2-yl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
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C17H17F2N3O2S
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1
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| 1 |
IC50 = 2300 nM
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CP0496461
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N-[[4-[4-(2-phenoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C27H35F3N4O3
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1
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| 1 |
IC50 = 2300 nM
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CP0568737
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N-[[4-(4-benzylpiperazin-1-yl)oxan-4-yl]methyl]-N-phenylpropanamide
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C26H35N3O2
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1
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| 1 |
IC50 = 2300 nM
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CP0571632
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7-methyl-9-(1-methylpiperidin-4-yl)-2-[(7-methylquinoxalin-6-yl)amino]purin-8-one
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C21H24N8O
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1
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| 1 |
IC50 = 2300 nM
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CP0387632
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(3aR,7aS)-7a-(3,4-dichlorophenyl)-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole
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C15H19Cl2N
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1
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| 1 |
IC50 = 2320 nM
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CP0456056
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2-(1-((5-(4-chlorophenyl)furan-2-yl)methyl)piperidin-4-yl)-1-(3-(hydroxymethyl)piperidin-1-yl)ethanone
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C24H31ClN2O3
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1
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| 1 |
IC50 = 2340 nM
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CP0909621
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3,6-bis(3-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazine
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C20H17N3O4S2
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1
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| 1 |
IC50 = 2350 nM
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CP0909620
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3-(4-(methylsulfinyl)phenyl)-N-(3-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazin-6-amine
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C20H18N4O3S2
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1
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| 1 |
IC50 = 2360 nM
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CP0534873
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N-[3-[2-[4-amino-1-[(1-methylpyrrolidin-3-yl)methyl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
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C28H26F3N7O
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1
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| 1 |
IC50 = 2380 nM
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CP0027098
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N-[2-[[cyclohexyl(2-hydroxyethyl)amino]methyl]-4-(hydroxymethyl)phenyl]-6-fluoro-8-(methylamino)-2-oxo-1H-quinoline-3-carboxamide
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C27H33FN4O4
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1
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| 1 |
IC50 = 2390 nM
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CP0454255
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N-[(1-methylpyrrol-2-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
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C25H29F3N4O
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1
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| 1 |
IC50 = 2400 nM
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CP0449376
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4-N-pyrrolidin-3-yl-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
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C17H16F3N5S
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1
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| 1 |
IC50 = 2400 nM
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CP0543081
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4-[ethyl-[(3S)-piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
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C21H24N4OS
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1
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| 1 |
IC50 = 2400 nM
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CP0525848
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[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[3-[4-(trifluoromethyl)phenyl]azetidin-1-yl]methanone
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C22H21F6NO5S
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1
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| 1 |
IC50 = 2400 nM
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CP0213280
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6-[[[1-[2-(6-methoxy-3-methylsulfonyl-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
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C27H31N5O6S
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1
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| 1 |
IC50 = 2410 nM
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CP0364838
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4-[[(3S,6R)-6-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C20H22N4OS
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1
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| 1 |
IC50 = 2450 nM
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CP0569959
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7-[(4-fluoropiperidin-1-yl)methyl]-3,8-dihydroxy-[1]benzofuro[3,2-c]chromen-6-one
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C21H18FNO5
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1
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| 1 |
IC50 = 2460 nM
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CP0074886
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(4R,10aS)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a]indole
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C13H17ClN2
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1
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| 1 |
IC50 = 2500 nM
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CP0485877
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2-[6-[(3aR,6aS)-2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol
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C19H20N6O
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1
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| 1 |
IC50 = 2500 nM
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CP0416902
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N-[4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]pyrimidin-2-yl]-1,3,4-thiadiazol-2-amine
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C20H18FN7S2
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1
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| 1 |
IC50 = 2500 nM
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CP0426239
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(2R)-9-[2-(2,4-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C19H26F2N2O2
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1
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| 1 |
IC50 = 2500 nM
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CP0014180
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2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-(1,2-oxazol-5-ylmethyl)-7,8-dihydro-1,6-naphthyridin-5-one
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C23H19FN4O4
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1
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| 1 |
IC50 = 2500 nM
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CP0372580
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3-(5-methyl-1,2,4-oxadiazol-3-yl)-N-[4-[2-(7-methylsulfonyl-1,2,4,5-tetrahydro-3-benzazepin-3-yl)ethyl]cyclohexyl]benzamide
Show/Hide
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C29H36N4O4S
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1
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| 1 |
IC50 = 2511.89 nM
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CP0486356
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5-[5-[3-[7-(2,5-dimethylpyrazol-3-yl)-1,2,4,5-tetrahydro-3-benzazepin-3-yl]propylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]-4-methyl-1,3-oxazole
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C25H31N7OS
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1
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| 1 |
IC50 = 2511.89 nM
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CP0076411
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3-phenyl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
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C22H20F3N3O3
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1
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| 1 |
IC50 = 2511.89 nM
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CP0124786
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3-pyridin-2-yl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
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C21H19F3N4O3
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1
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| 1 |
IC50 = 2511.89 nM
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CP0377578
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N-[(3S)-5-pyridin-4-yl-3,4-dihydro-2H-chromen-3-yl]-4-(trifluoromethoxy)benzamide
Show/Hide
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C22H17F3N2O3
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1
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| 1 |
IC50 = 2511.89 nM
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CP0384837
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N-[(1R,2R)-1-[3-(dimethylamino)propanoylamino]-2,3-dihydro-1H-inden-2-yl]-5-methyl-1H-indole-2-carboxamide
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C24H28N4O2
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1
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| 1 |
IC50 = 2511.89 nM
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CP0858970
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rac-1-(2-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)phenyl)-3-phenylpropan-1-one hydrochloride
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C35H39ClN2O3
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1
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| 1 |
IC50 = 2600 nM
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CP0155918
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4-amino-N-[(4-chlorophenyl)-cyclopropylmethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C22H25ClN6O
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1
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| 1 |
IC50 = 2600 nM
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CP0080989
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(4S,6R)-4-[2,4-difluoro-5-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]phenyl]-4,6-dimethyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C17H20F5N3S
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1
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| 1 |
IC50 = 2600 nM
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CP0314362
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4-[[4-amino-6-[3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2-yl)-2-(hydroxymethyl)phenyl]-1,3,5-triazin-2-yl]amino]-1-methylpyrrole-2-carbonitrile
Show/Hide
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C28H23FN8O2
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1
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| 1 |
IC50 = 2600 nM
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CP0563822
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N-[(3S,4S)-1-cyclohexyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C29H32F2N6O3
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1
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| 1 |
IC50 = 2600 nM
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CP0549547
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N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(2-fluorophenyl)propanamide
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C24H30FN3O
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1
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| 1 |
IC50 = 2600 nM
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CP0490947
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US9266876, 144
Show/Hide
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C24H24N8OS
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1
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| 1 |
IC50 = 2600 nM
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CP0480159
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(E)-N-hydroxy-3-[2-[2-(2-methyl-1H-indol-3-yl)ethyl]-3,4-dihydro-1H-isoquinolin-7-yl]prop-2-enamide
Show/Hide
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C23H25N3O2
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1
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| 1 |
IC50 = 2700 nM
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CP0453355
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4-[2-[(6-fluoro-2H-pyrazolo[3,4-b]pyridin-3-yl)methylamino]pyridin-4-yl]-3-methylbenzonitrile
Show/Hide
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C20H15FN6
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1
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| 1 |
IC50 = 2700 nM
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CP0257262
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5-[3-amino-4-fluoro-1-[3-(5-fluoropyridin-3-yl)phenyl]isoindol-1-yl]-1-ethyl-3-methylpyridin-2-one
Show/Hide
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C27H22F2N4O
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1
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| 1 |
IC50 = 2700 nM
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CP0449375
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4-N-[3-(dimethylamino)propyl]-2-N-methyl-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H22F3N5S
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1
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| 1 |
IC50 = 2700 nM
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CP0558613
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4-[methyl-[(3S)-piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C20H22N4OS
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1
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| 1 |
IC50 = 2700 nM
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CP0554756
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N-(1-cyclohexylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,2,4-oxadiazole-3-carboxamide
Show/Hide
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C20H24F2N4O2
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1
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| 1 |
IC50 = 2700 nM
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CP0558454
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N-(1-cyclohexylpiperidin-4-yl)-5-(2,4-difluorophenyl)-1,3,4-oxadiazole-2-carboxamide
Show/Hide
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C20H24F2N4O2
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1
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| 1 |
IC50 = 2700 nM
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CP0179714
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5-[(1R)-3-amino-4-fluoro-1-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]isoindol-1-yl]-1-ethyl-3-methylpyridin-2-one
Show/Hide
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C30H25FN4O
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1
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| 1 |
IC50 = 2800 nM
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CP0156942
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2-methyl-2-(3-pyridin-3-ylphenyl)-1,3-benzoxazin-4-amine
Show/Hide
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C20H17N3O
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1
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| 1 |
IC50 = 2800 nM
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CP0387877
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4-N-[3-(dimethylamino)propyl]-2-N-methyl-6-[4-(trifluoromethoxy)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C19H22F3N5OS
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1
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| 1 |
IC50 = 2800 nM
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CP0543592
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2-(4-chloropyrazol-1-yl)-1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C20H21ClF3N7O2S
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1
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| 1 |
IC50 = 2800 nM
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CP0254223
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1-(2-(3,5-dimethyl-1H-pyrazol-1-yl)-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C31H35F3N6O
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1
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| 1 |
IC50 = 2840 nM
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CP0011846
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1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one
Show/Hide
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C21H27NO3
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1
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| 1 |
IC50 = 2880 nM
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CP0363812
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3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]isoindol-1-amine
Show/Hide
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C28H19F3N4
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1
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| 1 |
IC50 = 2900 nM
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CP0184986
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6-[[[1-[2-[3-fluoro-6-(2-hydroxyethoxy)-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
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C27H30FN5O5
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1
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| 1 |
IC50 = 2900 nM
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CP0816819
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(E)-N-(Coumaran-5-methyl)-N-methyl-3-(2-fluoro-4-trifluoromethylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
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C20H20ClF4NO
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1
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| 1 |
IC50 = 2900 nM
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CP0961086
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(E)-N-(Chroman-7-methyl)-N-methyl-3-(4-trifluoromethylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
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C21H23ClF3NO
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1
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| 1 |
IC50 = 2900 nM
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CP0549548
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N-[[3-(4-benzylpiperazin-1-yl)oxetan-3-yl]methyl]-N-phenylpropanamide
Show/Hide
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C24H31N3O2
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1
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| 1 |
IC50 = 2900 nM
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CP0015195
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2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-(oxolan-2-ylmethyl)-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
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C24H24FN3O4
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1
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| 1 |
IC50 = 2900 nM
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CP0015231
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(1,1-dioxothian-4-yl)-[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone
Show/Hide
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C25H26FN3O5S
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1
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| 1 |
IC50 = 2900 nM
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CP0452879
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3-(1,4-oxazepan-4-yl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)azetidine-1-carboxamide
Show/Hide
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C26H34F3N5O2
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1
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| 1 |
IC50 = 3000 nM
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CP0471043
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3-fluoro-4-[4-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl]piperazin-1-yl]benzonitrile
Show/Hide
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C22H21F4N3O4S
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1
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| 1 |
IC50 = 3000 nM
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CP0060491
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10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
Show/Hide
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C20H23N
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2
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| 1 |
IC50 = 3000 nM
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| 2 |
IC50 = 10000 nM
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CP0531626
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methyl N-[4-[4-amino-5-(3-amino-4-chlorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-1-bicyclo[2.2.2]octanyl]carbamate
Show/Hide
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C22H25ClN6O2
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2
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| 1 |
IC50 = 3000 nM
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| 2 |
IC50 = 9900 nM
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CP0572652
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1-[2-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-oxoethyl]-3H-indol-2-one
Show/Hide
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C25H25F3N6O3S
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1
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| 1 |
IC50 = 3000 nM
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CP0429471
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2-(2-hydroxyethyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
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C25H33F3N4O2
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1
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| 1 |
IC50 = 3080 nM
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CP0452884
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2-(pyridin-3-yl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
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C27H30F3N5O
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1
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| 1 |
IC50 = 3080 nM
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CP0009993
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N-[5-(3-methoxyphenyl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutanamide
Show/Hide
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C19H26N4O2
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1
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| 1 |
IC50 = 3080 nM
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CP0103195
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(3S)-7-fluoro-3-pyridin-4-yl-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
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C23H16FN5
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1
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| 1 |
IC50 = 3100 nM
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CP0440994
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5-[(1R)-3-amino-4,6-difluoro-1-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]isoindol-1-yl]-1-ethyl-3-methylpyridin-2-one
Show/Hide
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C30H24F2N4O
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1
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| 1 |
IC50 = 3100 nM
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CP0441695
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1-(4-chlorophenyl)-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
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C15H20ClN5
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1
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| 1 |
IC50 = 3100 nM
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CP0689611
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(2-fluoro-4-methoxylphenyl)prop-2-en-1amine Hydrochloride
Show/Hide
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C21H25ClFNO2
|
1
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| 1 |
IC50 = 3100 nM
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CP0530023
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4-ethyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C19H28N2O2
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1
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| 1 |
IC50 = 3100 nM
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CP0420196
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4-butoxy-N-[2-(1H-indol-3-yl)ethyl]benzenesulfonamide
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C20H24N2O3S
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1
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| 1 |
IC50 = 3180 nM
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CP0504540
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(E)-N-hydroxy-3-[3-[2-(2-methyl-1H-indol-3-yl)ethyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]prop-2-enamide
Show/Hide
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C24H27N3O2
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1
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| 1 |
IC50 = 3200 nM
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CP0069417
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(E)-3-(4-methoxyphenyl)-N-methyl-N-(6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-ylmethyl)prop-2-en-1-amine;hydrochloride
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C23H30ClNO
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1
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| 1 |
IC50 = 3200 nM
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CP0747670
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(E)-N-(Chroman-7-methyl)-N-methyl-3-(2-fluoro-4-trifluoromethylphenyl)prop2-en-1-amine Hydrochloride
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C21H22ClF4NO
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1
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| 1 |
IC50 = 3200 nM
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CP0549544
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N-[[4-(4-benzylpiperazin-1-yl)-2,2-dimethyloxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C28H37F3N4O2
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1
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| 1 |
IC50 = 3200 nM
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CP0014653
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2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-(oxolan-3-yl)-7,8-dihydro-1,6-naphthyridin-5-one
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C23H22FN3O4
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1
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| 1 |
IC50 = 3200 nM
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CP0071568
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5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrid[4,3-b]indol-1-one;hydrochloride
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C17H18N4O
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1
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| 1 |
IC50 = 3235.94 nM
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CP0921073
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-2,4-difluorobenzenesulfonamide
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C24H28F2N4O4S
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1
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| 1 |
IC50 = 3235.94 nM
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CP0471006
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3-Fluoro-4-[4-(2-isopropoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzonitrile
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C22H24FN3O4S
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1
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| 1 |
IC50 = 3300 nM
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CP0521777
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6-[methyl-[[4-(trifluoromethyl)phenyl]methyl]amino]-N-phenylpyrimidine-4-carboxamide
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C20H17F3N4O
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1
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| 1 |
IC50 = 3300 nM
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CP0110087
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CAS_1794
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C12H18ClN7O
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1
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| 1 |
IC50 = 3300 nM
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CP0010658
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5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Show/Hide
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C22H30N6O4S
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2
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| 1 |
IC50 = 3311.31 nM
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| 2 |
IC50 = 100000 nM
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CP0485233
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1-(4-chloro-2-(hydroxymethyl)phenyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
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C25H26ClF3N4O2
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1
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| 1 |
IC50 = 3330 nM
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CP0154125
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4,4-difluoro-N-[(1S)-3-[(1S,5R)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-(5-methylthiophen-2-yl)propyl]cyclohexane-1-carboxamide
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C28H41F2N5OS
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1
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| 1 |
IC50 = 3380 nM
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CP0036757
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3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
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C19H24N2
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2
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| 1 |
IC50 = 3388.44 nM
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| 2 |
IC50 = 3400 nM
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CP0425955
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6-fluoro-1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C24H27FN4O2
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1
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| 1 |
IC50 = 3400 nM
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CP0425956
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4-[3-[4-(4-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
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C23H25FN4O3
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1
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| 1 |
IC50 = 3400 nM
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CP0411415
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1-[6,6-bis(4-fluorophenyl)hexyl]-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine
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C32H40F2N2O3
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1
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| 1 |
IC50 = 3400 nM
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CP0517216
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N-[(3S,4S)-1-cyclohexyl-3-[[(1R)-1-pyridin-2-ylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C29H33F2N5O3
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1
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| 1 |
IC50 = 3400 nM
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CP0496456
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N-[[4-[4-(2-propoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C24H37F3N4O3
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1
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| 1 |
IC50 = 3400 nM
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CP0573261
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N-[[4-(2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C28H35F3N4O2
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1
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| 1 |
IC50 = 3400 nM
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CP0636848
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rac-1-(2-(2-hydroxy-3-(4-phenylpiperidin-1-yl)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
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C29H34ClNO3
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1
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| 1 |
IC50 = 3460 nM
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CP0316371
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5-Chloro-3-ethyl-1-(4-fluoro-phenyl)-1H-indole
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C16H13ClFN
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1
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| 1 |
IC50 = 3500 nM
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CP0506349
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N-[(2,4-dichlorophenyl)methyl]-1-[[1-[5-(trifluoromethyl)pyridin-2-yl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
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C24H23Cl2F3N4O
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1
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| 1 |
IC50 = 3500 nM
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CP0106403
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2-(1-(3-ethoxy-4-methoxybenzyl)piperidin-4-ylamino)benzo[d]oxazole-5-sulfonamide
Show/Hide
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C22H28N4O5S
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1
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| 1 |
IC50 = 3500 nM
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CP0169655
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3-(2-cyclopropylpyridin-4-yl)-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
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C26H20FN5
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1
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| 1 |
IC50 = 3500 nM
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CP0115542
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4-amino-N-[1-(4-chlorophenyl)-2-phenylethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C26H27ClN6O
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1
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| 1 |
IC50 = 3500 nM
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CP0210820
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(4S)-4-[2,4-difluoro-5-[[[1-(trifluoromethyl)cyclopropyl]amino]methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C16H18F5N3S
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1
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| 1 |
IC50 = 3500 nM
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CP0097118
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4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-2-ylpropyl]cyclohexane-1-carboxamide
Show/Hide
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C27H39F2N5OS
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1
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| 1 |
IC50 = 3500 nM
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CP0568736
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N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C24H29F3N4O
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1
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| 1 |
IC50 = 3500 nM
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CP0012685
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2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-(furan-2-ylmethyl)-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
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C24H20FN3O4
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1
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| 1 |
IC50 = 3500 nM
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CP0558729
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12-methyl-8-(2-phenylethyl)-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
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C19H26N2O2
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1
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| 1 |
IC50 = 3600 nM
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CP0496460
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N-[[4-(4-benzylpiperazin-1-yl)thian-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C26H33F3N4OS
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1
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| 1 |
IC50 = 3600 nM
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CP0014634
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[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-(oxolan-3-yl)methanone
Show/Hide
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C24H24FN3O4
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1
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| 1 |
IC50 = 3600 nM
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CP0571639
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3-[(2,2-dimethyl-3H-1-benzofuran-5-yl)methyl]-1-[(5-fluoropyridin-2-yl)methyl]-1-(1-methylpiperidin-4-yl)urea
Show/Hide
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C24H31FN4O2
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1
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| 1 |
IC50 = 3610 nM
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CP0376793
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(3aS,7aR)-7a-(3,4-dichlorophenyl)-1,2,3,3a,4,5,6,7-octahydroisoindole
Show/Hide
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C14H17Cl2N
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1
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| 1 |
IC50 = 3640 nM
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CP0365726
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3-[[(1R,2S)-2-aminocyclohexyl]amino]-5-[3-(triazol-2-yl)anilino]-1,2,4-triazine-6-carboxamide
Show/Hide
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C18H22N10O
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1
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| 1 |
IC50 = 3700 nM
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CP0722967
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5-(1H-indol-4-ylamino)-3-((1R,2S)-2-aminocyclohexylamino)-1,2,4-triazine-6-carboxamide
Show/Hide
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C18H22N8O
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1
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| 1 |
IC50 = 3700 nM
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CP0407602
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1-benzhydryl-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C31H31F3N4O
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1
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| 1 |
IC50 = 3800 nM
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CP0110666
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7-fluoro-3-(5-methoxy-4,6-dimethylpyridin-2-yl)-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
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C26H22FN5O
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1
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| 1 |
IC50 = 3800 nM
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CP0934042
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(E)-N-(Chroman-7-methyl)-N-methyl-3-(4-methylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
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C21H26ClNO
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1
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| 1 |
IC50 = 3800 nM
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CP0538857
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2-phenyl-4-[(3S)-piperidin-3-yl]oxythieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C19H19N3O2S
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1
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| 1 |
IC50 = 3800 nM
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CP0532055
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3,3-dimethyl-N-[4-[1-(oxan-4-yl)pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl]azetidine-1-carboxamide
Show/Hide
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C23H27N5O2
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1
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| 1 |
IC50 = 3800 nM
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CP0012684
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2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-methyl-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
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C20H18FN3O3
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1
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| 1 |
IC50 = 3800 nM
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CP0485354
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N-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]-3-[4-(trifluoromethyl)piperidin-1-yl]azetidine-1-carboxamide
Show/Hide
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C27H33F6N5O
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1
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| 1 |
IC50 = 3870 nM
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CP0179956
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N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide
Show/Hide
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C17H20F6N2O3
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1
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| 1 |
IC50 = 3890.45 nM
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CP0398166
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N-[2-(azepan-1-yl)ethyl]-1-[(3,4-dichlorophenyl)methyl]triazol-4-amine
Show/Hide
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C17H23Cl2N5
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1
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| 1 |
IC50 = 3900 nM
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CP0751236
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(E)-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-N-methyl-3-(4-(trifluoromethyl)phenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
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C20H21ClF3NO2
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1
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| 1 |
IC50 = 3900 nM
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CP0539898
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2-methyl-9-(2-phenylethyl)-4-propan-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C20H30N2O2
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1
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| 1 |
IC50 = 3900 nM
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CP0404745
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1-(((1R,2R)-2-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C25H33F3N4O2
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1
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| 1 |
IC50 = 3960 nM
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CP0782210
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(+)-((1S,2S)-2-(5-chloro-2-(2-fluoroallyloxy)phenyl)cyclopropyl)methanamine hydrochloride
Show/Hide
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C13H16Cl2FNO
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1
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| 1 |
IC50 = 3980 nM
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CP0461487
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5-methyl-3-[3-[3-[[4-methyl-5-(oxan-4-yl)-1,2,4-triazol-3-yl]sulfanyl]propyl]-1,2,4,5-tetrahydro-3-benzazepin-7-yl]-1,2-oxazole
Show/Hide
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C25H33N5O2S
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1
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| 1 |
IC50 = 3981.07 nM
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CP0041749
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1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
Show/Hide
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C20H21FN2O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0124787
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3-phenyl-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
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C22H20F3N3O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0124788
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3-pyridin-2-yl-8-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
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C21H19F3N4O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0163144
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3-(6-fluoropyridin-2-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
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C21H18F4N4O3
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1
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| 1 |
IC50 = 3981.07 nM
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CP0437804
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5-methyl-2-phenyl-N-[(3S)-5-pyridin-4-yl-3,4-dihydro-2H-chromen-3-yl]triazole-4-carboxamide
Show/Hide
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C24H21N5O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0136867
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5-chloro-6-methylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
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C17H22ClN7O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0235625
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5-methoxy-6-propylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
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C20H29N7O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0314046
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6-[[(2R)-1-amino-4-methylpentan-2-yl]amino]-4-[(6-tert-butylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
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C20H31N7O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0382344
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(6-cyclopropylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
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C19H25N7O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0411948
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N-[(1S,2S)-1-[3-(dimethylamino)propanoylamino]-2,3-dihydro-1H-inden-2-yl]-5,6-difluoro-1H-indole-2-carboxamide
Show/Hide
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C23H24F2N4O2
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1
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| 1 |
IC50 = 3981.07 nM
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CP0307921
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N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
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C24H26FN3O3S2
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1
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| 1 |
IC50 = 4000 nM
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CP0576016
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US8975247, EBP101
Show/Hide
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C24H21ClN2
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1
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| 1 |
IC50 = 4000 nM
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CP0190732
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N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]phenyl]acetamide
Show/Hide
|
C23H29N9O
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1
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| 1 |
IC50 = 4000 nM
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CP0851567
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3-(3-(methylsulfonyl)phenyl)-6-(4-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazine
Show/Hide
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C20H17N3O4S2
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1
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| 1 |
IC50 = 4000 nM
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CP0527836
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(2R)-4-ethyl-9-[2-(2-fluorophenyl)ethyl]-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H27FN2O2
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1
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| 1 |
IC50 = 4000 nM
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CP0452885
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1-(1-phenyl-2-(1H-pyrazol-1-yl)ethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C29H31F3N6O
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1
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| 1 |
IC50 = 4040 nM
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CP0573080
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1-[4-[3-[[1-(3,4-dichlorophenyl)-5-methylpyrazol-3-yl]methoxy]propyl]piperazin-1-yl]ethanone
Show/Hide
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C20H26Cl2N4O2
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1
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| 1 |
IC50 = 4084 nM
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CP0334974
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N-[1-[2-(tert-butylcarbamoylamino)ethyl]piperidin-3-yl]-3,5-dichlorobenzamide
Show/Hide
|
C19H28Cl2N4O2
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1
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| 1 |
IC50 = 4100 nM
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CP0558383
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6-[(4-fluorophenyl)methyl-methylamino]-N-(4-propan-2-yloxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C22H23FN4O2
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1
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| 1 |
IC50 = 4100 nM
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CP0300580
|
2-(4-chlorophenyl)-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide
Show/Hide
|
C20H21ClN4O
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1
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| 1 |
IC50 = 4100 nM
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CP0473759
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4-(2-hydroxyphenyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
|
C29H33F3N4O2
|
1
|
| 1 |
IC50 = 4120 nM
|
|
|
|
CP0451981
|
(3aS,7aR)-7a-(3,4-dichlorophenyl)-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole
Show/Hide
|
C15H19Cl2N
|
1
|
| 1 |
IC50 = 4140 nM
|
|
|
|
CP0407595
|
N-[(2,4-dichloro-6-hydroxyphenyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C25H24Cl2F3N3O2
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0539164
|
6-[(4-fluorophenyl)methyl-methylamino]-N-(1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
Show/Hide
|
C15H13FN6OS
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0565276
|
4-(4-cyclopropyl-2-piperidin-4-yl-1,3-thiazol-5-yl)-N-(2-methylpyridin-4-yl)pyrimidin-2-amine
Show/Hide
|
C21H24N6S
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0551916
|
1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-pyrrolo[2,3-b]pyridin-1-ylethanone
Show/Hide
|
C24H24F3N7O2S
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0014181
|
1-[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-3-methylsulfonylpropan-1-one
Show/Hide
|
C23H24FN3O5S
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
|
CP0453354
|
4-[2-[(6-amino-2H-pyrazolo[3,4-b]pyridin-3-yl)methylamino]pyridin-4-yl]-3-methylbenzonitrile
Show/Hide
|
C20H17N7
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0445227
|
6-[[[1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-7-methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C27H30FN5O4
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0556603
|
US8975247, EBP882
Show/Hide
|
C24H28ClN3
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0224530
|
US9045498, 8
Show/Hide
|
C17H19F6N3OS
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0477789
|
[2-(4,4-difluoropiperidin-1-yl)-5-methylsulfonylphenyl]-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
|
C24H23F3N4O3S
|
1
|
| 1 |
IC50 = 4300 nM
|
|
|
|
CP0637108
|
rac-1-(2-(2-hydroxy-3-(4-p-tolylpiperazin-1-yl)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
Show/Hide
|
C29H35ClN2O3
|
1
|
| 1 |
IC50 = 4310 nM
|
|
|
|
CP0429536
|
(3aR,7aS)-7a-(3,4-dichlorophenyl)-2-ethyl-3,3a,4,5,6,7-hexahydro-1H-isoindole
Show/Hide
|
C16H21Cl2N
|
1
|
| 1 |
IC50 = 4330 nM
|
|
|
|
CP0039740
|
5-(3-butylpyrrolidin-3-yl)-1H-indole
Show/Hide
|
C16H22N2
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0425957
|
1-[3-[4-(1H-indol-5-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C25H29N3O
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0507697
|
4-[3-[4-(6-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
|
C23H25FN4O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0551802
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-propyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H28F2N6O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0519216
|
US9266876, 113
Show/Hide
|
C26H26N8O2S
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0014982
|
2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-6-propan-2-yl-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
|
C22H22FN3O3
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0128076
|
8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C17H17ClN4
|
1
|
| 1 |
IC50 = 4466.84 nM
|
|
|
|
CP0547527
|
[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[2-(3-fluorophenyl)-5-methylsulfonylphenyl]methanone
Show/Hide
|
C25H19F2N3O3S
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0485876
|
6-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]quinolin-7-ol
Show/Hide
|
C23H29N5O
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0535146
|
(2R)-4-cyclopropyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C20H28N2O2
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0568051
|
5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]phenyl]pyrimidin-2-amine
Show/Hide
|
C31H40F2N6O3
|
1
|
| 1 |
IC50 = 4500 nM
|
|
|
|
CP0327632
|
1-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethanol
Show/Hide
|
C16H13ClFNO
|
1
|
| 1 |
IC50 = 4550 nM
|
|
|
|
CP0567047
|
6-[[[1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-7,8-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C28H32FN5O4
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0688715
|
(E)-N-(1,4-Benzodioxine-7-methyl)-N-methyl-3-(4-methylphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C20H24ClNO2
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0535419
|
1-cyclopropyl-3-[4-[1-(oxan-4-yl)pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl]urea
Show/Hide
|
C21H23N5O2
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0531395
|
N-(1H-indol-5-ylmethyl)-3-[[4-(trifluoromethyl)phenoxy]methyl]azetidine-1-carboxamide
Show/Hide
|
C21H20F3N3O2
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0003287
|
N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutanamide
Show/Hide
|
C19H26N4O2
|
1
|
| 1 |
IC50 = 4610 nM
|
|
|
|
CP0395249
|
methyl 2-[(4-bromophenyl)sulfonylamino]-3-(1H-indol-3-yl)propanoate
Show/Hide
|
C18H17BrN2O4S
|
1
|
| 1 |
IC50 = 4660 nM
|
|
|
|
CP0506010
|
4-methyl-2-phenyl-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperazine-1-carboxamide
Show/Hide
|
C29H34F3N5O
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0524602
|
[4-[7-amino-5-[(1,2,2,6,6-pentamethylpiperidin-4-yl)amino]-6-phenylpyrazolo[1,5-a]pyrimidin-3-yl]phenyl]-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]methanone
Show/Hide
|
C34H41N7O2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0539842
|
(2R)-4-ethyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H28N2O2
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0543476
|
2-(benzimidazol-1-yl)-1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
|
C24H24F3N7O2S
|
1
|
| 1 |
IC50 = 4700 nM
|
|
|
|
CP0387630
|
(3aS,7aR)-7a-(3,4-dichlorophenyl)-2-ethyl-3,3a,4,5,6,7-hexahydro-1H-isoindole
Show/Hide
|
C16H21Cl2N
|
1
|
| 1 |
IC50 = 4730 nM
|
|
|
|
CP0205798
|
(E)-N-hydroxy-3-[2-[2-(2-methyl-1H-indol-3-yl)ethyl]-1,3-dihydroisoindol-5-yl]prop-2-enamide
Show/Hide
|
C22H23N3O2
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0197532
|
2-amino-1-[3-(3,4-difluoroanilino)-2-(4-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
|
C22H22F3N5O
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0187510
|
(3S)-3-[2-(difluoromethyl)pyridin-4-yl]-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
|
C24H16F3N5
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0115128
|
US8865706, 16
Show/Hide
|
C18H20F2N4OS
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0118373
|
US8962616, 22
Show/Hide
|
C18H19F2N3O2S
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0549545
|
N-[[4-(1-benzylpiperidin-4-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C27H34F3N3O2
|
1
|
| 1 |
IC50 = 4800 nM
|
|
|
|
CP0637784
|
rac-1-(2-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropoxy)-5-fluorophenyl)-3-phenylpropan-1-one hydrochloride
Show/Hide
|
C35H38ClFN2O3
|
1
|
| 1 |
IC50 = 4840 nM
|
|
|
|
CP0510116
|
3-(hydroxymethyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
|
C24H31F3N4O2
|
1
|
| 1 |
IC50 = 4890 nM
|
|
|
|
CP0400789
|
(5-chloro-1-methylindol-2-yl)-[6-[(dimethylamino)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Show/Hide
|
C22H24ClN3O
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0456018
|
1-(2,4-dichlorophenyl)-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C15H19Cl2N5
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0724426
|
(4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1-methyl-1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
|
C17H18F2N4OS
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0463932
|
2-phenyl-4-piperidin-3-ylsulfanylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C19H19N3OS2
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0960371
|
(R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-(3-(4-(3-phenyl-1,2,4-oxadiazol-5-yl)piperazin-1-yl)propyl)-1H-purine-2,6(3H,7H)-dione hydrochloride
Show/Hide
|
C30H39ClN10O3
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0747132
|
(R)-2-amino-1-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)propan-1-one
Show/Hide
|
C24H25F3N6O3
|
1
|
| 1 |
IC50 = 4920 nM
|
|
|
|
CP0556046
|
US8975247, EBP106
Show/Hide
|
C19H11Cl4N3O
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0563072
|
US8975247, EBP484
Show/Hide
|
C21H24ClN3O2
|
1
|
| 1 |
IC50 = 5000 nM
|
|
|
|
CP0122485
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5,6-dimethoxypyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C18H25N7O3
|
1
|
| 1 |
IC50 = 5011.87 nM
|
|
|
|
CP0571705
|
1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-[3-(trifluoromethyl)pyrazol-1-yl]ethanone
Show/Hide
|
C21H21F6N7O2S
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0451707
|
1-(3,4-dichlorophenyl)-5-methyl-3-(2-pyrrolidin-1-ylethoxymethyl)pyrazole
Show/Hide
|
C17H21Cl2N3O
|
1
|
| 1 |
IC50 = 5123 nM
|
|
|
|
CP0472332
|
1-(3-fluorophenyl)-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C15H20FN5
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0909619
|
N-ethyl-N-(2-fluoro-4-(3-(4-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)benzyl)ethanamine
Show/Hide
|
C24H25FN4O2S
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0577506
|
2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[2-(trifluoromethyl)-4-[6-(trifluoromethyl)pyridin-3-yl]-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
|
C21H21F6N7OS
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0022971
|
4-Amino-N-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C19H21ClN6O
|
1
|
| 1 |
IC50 = 5235 nM
|
|
|
|
CP0376794
|
(3aR,6aS)-3a-(3,4-dichlorophenyl)-2,3,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole
Show/Hide
|
C13H15Cl2N
|
1
|
| 1 |
IC50 = 5280 nM
|
|
|
|
CP0208887
|
5-(4-chlorophenyl)-N-[(1-methyl-1,2,3,4-tetrahydroquinolin)-6-yl]furan-2-carboxamide
Show/Hide
|
C21H19ClN2O2
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0455528
|
5-fluoro-1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H27FN4O2
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0282368
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]piperidin-3-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C20H30Cl2N4O2
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0340177
|
4-[(3S,4S)-3-(aminomethyl)-4-(4-chlorophenyl)sulfonyl-3-hydroxypyrrolidin-1-yl]sulfonyl-3-chlorobenzonitrile
Show/Hide
|
C18H17Cl2N3O5S2
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0494169
|
methyl N-[4-[4-amino-5-(3-amino-4-chlorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexyl]carbamate
Show/Hide
|
C20H23ClN6O2
|
2
|
| 1 |
IC50 = 5300 nM
|
|
|
| 2 |
IC50 = 25000 nM
|
|
|
|
CP0012686
|
1-[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethanone
Show/Hide
|
C21H20FN3O3
|
1
|
| 1 |
IC50 = 5300 nM
|
|
|
|
CP0208389
|
1-(1-phenyl-2-(pyrazin-2-yl)ethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C30H31F3N6O
|
1
|
| 1 |
IC50 = 5340 nM
|
|
|
|
CP0527919
|
4-[4-(4-fluorophenyl)-2-morpholin-4-yl-1,3-thiazol-5-yl]-N-(4-piperazin-1-ylphenyl)pyrimidin-2-amine
Show/Hide
|
C27H28FN7OS
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0426647
|
(3aR,6aS)-3a-(3,4-dichlorophenyl)-2-methyl-1,3,4,5,6,6a-hexahydrocyclopenta[c]pyrrole
Show/Hide
|
C14H17Cl2N
|
1
|
| 1 |
IC50 = 5430 nM
|
|
|
|
CP0278310
|
6-chloro-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
|
C24H34ClN5O3S
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0356162
|
3-(3-pyrimidin-5-ylphenyl)-3-[2-(trifluoromethyl)pyridin-4-yl]isoindol-1-amine
Show/Hide
|
C24H16F3N5
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0517202
|
N-[(3S,4S)-1-cyclohexyl-3-(dimethylcarbamoyl)piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C24H30F2N4O3
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0024732
|
5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide
Show/Hide
|
C26H27N5O2
|
2
|
| 1 |
IC50 = 5550 nM
|
|
|
| 2 |
IC50 = 5600 nM
|
|
|
|
CP0225649
|
2-amino-1-[3-(4-fluoroanilino)-2-(4-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
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C22H23F2N5O
|
1
|
| 1 |
IC50 = 5600 nM
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CP0527397
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2-amino-1-[3-(4-chloro-3-fluoroanilino)-2-(4-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
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C22H22ClF2N5O
|
1
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| 1 |
IC50 = 5600 nM
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CP0546745
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6-[methyl-[[6-(trifluoromethyl)pyridin-3-yl]methyl]amino]-N-phenylpyrimidine-4-carboxamide
Show/Hide
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C19H16F3N5O
|
1
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| 1 |
IC50 = 5600 nM
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CP0527916
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4-[4-(4-fluorophenyl)-2-pyrrolidin-1-yl-1,3-thiazol-5-yl]-N-(4-piperazin-1-ylphenyl)pyrimidin-2-amine
Show/Hide
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C27H28FN7S
|
1
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| 1 |
IC50 = 5600 nM
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CP0418474
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CHEMBL4848514
Show/Hide
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C24H23ClN4O
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1
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| 1 |
IC50 = 5600 nM
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CP0550340
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1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-(5-methylpyrazol-1-yl)ethanone
Show/Hide
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C21H24F3N7O2S
|
1
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| 1 |
IC50 = 5600 nM
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CP0578734
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(1R)-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-(pentylamino)ethanol
Show/Hide
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C18H20F6N2O
|
1
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| 1 |
IC50 = 5600 nM
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CP0492802
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N-[3-[2-[4-amino-1-[(1-methylpiperidin-4-yl)methyl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C29H28F3N7O
|
1
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| 1 |
IC50 = 5620 nM
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CP0064841
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(2,8-Bis-trifluoromethyl-quinolin-4-yl)-(1-methyl-piperidin-2-yl)-methanol
Show/Hide
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C17H16F6N2O
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1
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| 1 |
IC50 = 5623.41 nM
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CP0387641
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(3aS,6aR)-3a-(3,4-dichlorophenyl)-2-methyl-1,3,4,5,6,6a-hexahydrocyclopenta[c]pyrrole
Show/Hide
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C14H17Cl2N
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1
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| 1 |
IC50 = 5640 nM
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CP0466587
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2-amino-1-[3-(4-fluoroanilino)-2-(3-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
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C22H23F2N5O
|
1
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| 1 |
IC50 = 5700 nM
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CP0458254
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7-fluoro-1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C24H27FN4O2
|
1
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| 1 |
IC50 = 5700 nM
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CP0687606
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rac-4-Fluoro-1-(pyridin-4-yl)-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine
Show/Hide
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C23H16FN5
|
1
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| 1 |
IC50 = 5700 nM
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CP0086258
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2-methyl-2-(3-pyrimidin-5-ylphenyl)-1,3-benzoxazin-4-amine
Show/Hide
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C19H16N4O
|
1
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| 1 |
IC50 = 5700 nM
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CP0409349
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1-benzyl-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C19H15N3
|
1
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| 1 |
IC50 = 5700 nM
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CP0517201
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N-[(3S,4S)-1-(cyclopropylmethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C27H28F2N6O3
|
1
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| 1 |
IC50 = 5700 nM
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CP0013265
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[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-(oxan-4-yl)methanone
Show/Hide
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C25H26FN3O4
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1
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| 1 |
IC50 = 5700 nM
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CP0201658
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5-(4-cyanophenyl)-N-(3-methylphenyl)furan-2-carboxamide
Show/Hide
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C19H14N2O2
|
1
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| 1 |
IC50 = 5800 nM
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CP0282366
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N-[[1-[2-(tert-butylcarbamoylamino)ethyl]pyrrolidin-3-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
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C19H28Cl2N4O2
|
1
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| 1 |
IC50 = 5800 nM
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CP0012668
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cyclopropyl-[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone
Show/Hide
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C23H22FN3O3
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1
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| 1 |
IC50 = 5800 nM
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CP0327633
|
MDL-74156
Show/Hide
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C19H22N2O3
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1
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| 1 |
IC50 = 5888.44 nM
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CP0177354
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6-[[[1-[2-[3-(hydroxymethyl)-6-methoxy-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
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C27H31N5O5
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1
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| 1 |
IC50 = 5900 nM
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CP0507047
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4-[[(2S,3S)-2-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C20H22N4OS
|
1
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| 1 |
IC50 = 5900 nM
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CP0525849
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[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[3-[4-(trifluoromethyl)phenyl]azetidin-1-yl]methanone
Show/Hide
|
C21H19F6NO4S
|
1
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| 1 |
IC50 = 5900 nM
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CP0572644
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2-imidazo[4,5-b]pyridin-3-yl-1-[(2R)-2-methyl-4-[4-(2-propylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
|
C24H25F3N8OS
|
1
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| 1 |
IC50 = 5900 nM
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CP0154391
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2-methyl-2-(3-pyrimidin-5-ylphenyl)-1,3-benzothiazin-4-amine
Show/Hide
|
C19H16N4S
|
1
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| 1 |
IC50 = 6000 nM
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CP0421437
|
2-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]-5-(1H-pyrazol-4-yl)phenol
Show/Hide
|
C23H30N6O
|
1
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| 1 |
IC50 = 6000 nM
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CP0572677
|
2-(6-piperidin-4-yloxypyridazin-3-yl)-5-pyrazol-1-ylphenol
Show/Hide
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C18H19N5O2
|
1
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| 1 |
IC50 = 6000 nM
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CP0494170
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methyl N-[4-[4-amino-5-(5-amino-4-chloro-2-fluorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-1-bicyclo[2.2.2]octanyl]carbamate
Show/Hide
|
C22H24ClFN6O2
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2
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| 1 |
IC50 = 6000 nM
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| 2 |
IC50 > 30000 nM
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CP0540230
|
4-(4-aminopiperidin-1-yl)-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidin-2-amine
Show/Hide
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C18H18F3N5S
|
1
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| 1 |
IC50 = 6100 nM
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CP0210818
|
(4S)-4-[2,4-difluoro-5-[(2,2,2-trifluoroethylamino)methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
|
C14H16F5N3S
|
1
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| 1 |
IC50 = 6100 nM
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CP0045630
|
2-[3-(3-chlorophenyl)phenyl]-2-methyl-5,6-dihydro-1,3-oxazin-4-amine
Show/Hide
|
C17H17ClN2O
|
1
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| 1 |
IC50 = 6150 nM
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CP0379280
|
2-[3-[4-[1-(benzenesulfonyl)indol-4-yl]piperazin-1-yl]propoxy]benzamide
Show/Hide
|
C28H30N4O4S
|
1
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| 1 |
IC50 = 6200 nM
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CP0533168
|
4-methyl-9-(2-phenylethyl)-2-propan-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C20H30N2O2
|
1
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| 1 |
IC50 = 6200 nM
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|
|
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CP0576564
|
N-[4-[[2-[4-fluoro-2-(2-fluoropropan-2-yl)phenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]phenyl]-1-(3-fluoropropyl)azetidin-3-amine
Show/Hide
|
C30H29F3N4OS
|
1
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| 1 |
IC50 = 6200 nM
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CP0012915
|
1-[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-2-methylsulfonylethanone
Show/Hide
|
C22H22FN3O5S
|
1
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| 1 |
IC50 = 6200 nM
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CP0425959
|
4-[3-[4-(7-fluoro-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
|
C23H25FN4O3
|
1
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| 1 |
IC50 = 6300 nM
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|
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CP0482046
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1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydro-1,8-naphthyridin-2-one
Show/Hide
|
C23H27N5O2
|
1
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| 1 |
IC50 = 6300 nM
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|
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CP0572656
|
Branaplam
Show/Hide
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C22H27N5O2
|
1
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| 1 |
IC50 = 6300 nM
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CP0067409
|
3-(2-fluorophenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
|
C22H19F4N3O3
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0377581
|
N-[(3S)-5-pyridin-4-yl-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C22H18F3N3O3
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1
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| 1 |
IC50 = 6309.57 nM
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CP0416294
|
N-[(3S)-5-pyrimidin-5-yl-3,4-dihydro-2H-chromen-3-yl]-6-(3,3,3-trifluoropropoxy)pyridine-3-carboxamide
Show/Hide
|
C22H19F3N4O3
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0443560
|
4-butoxy-N-[(3S)-5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]benzamide
Show/Hide
|
C25H33N3O3
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0084803
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C18H25N7O
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0085144
|
6-(2-aminoethylamino)-4-[(5-methyl-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C16H23N7O
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0122484
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(6-propylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C19H27N7O
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0008168
|
CAS_136434-34-9
Show/Hide
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C18H19NOS
|
1
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| 1 |
IC50 = 6309.57 nM
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CP0010657
|
CAS_99200-09-6
Show/Hide
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C22H25F2NO4
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1
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| 1 |
IC50 = 6309.57 nM
|
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CP0416899
|
N-[(1S,2R)-1-[3-(dimethylamino)propanoylamino]-2,3-dihydro-1H-inden-2-yl]-5-methyl-1H-indole-2-carboxamide
Show/Hide
|
C24H28N4O2
|
1
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| 1 |
IC50 = 6309.57 nM
|
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CP0076562
|
6-tert-butylsulfonyl-N-(5-methyl-1H-pyrazol-3-yl)quinolin-4-amine
Show/Hide
|
C17H20N4O2S
|
1
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| 1 |
IC50 = 6371 nM
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CP0387635
|
(3aS,6aR)-3a-(3,4-dichlorophenyl)-2,3,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole
Show/Hide
|
C13H15Cl2N
|
1
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| 1 |
IC50 = 6400 nM
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CP0489093
|
5-(1-azabicyclo[2.2.2]octan-3-yl)-3-(5-pyridin-3-ylfuran-2-yl)-1,2,4-oxadiazole
Show/Hide
|
C18H18N4O2
|
1
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| 1 |
IC50 = 6400 nM
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CP0335314
|
3-(2,6-dimethylpyridin-4-yl)-7-fluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
|
C25H20FN5
|
1
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| 1 |
IC50 = 6400 nM
|
|
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CP0013266
|
[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-(1,2-oxazol-5-yl)methanone
Show/Hide
|
C23H19FN4O4
|
1
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| 1 |
IC50 = 6400 nM
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CP0387638
|
(3aR,7aS)-7a-(3,4-dichlorophenyl)-1,2,3,3a,4,5,6,7-octahydroisoindole
Show/Hide
|
C14H17Cl2N
|
1
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| 1 |
IC50 = 6480 nM
|
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CP0067596
|
4-amino-N-[1-(4-chlorophenyl)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C21H25ClN6O
|
1
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| 1 |
IC50 = 6495 nM
|
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CP0288406
|
(2S)-2-amino-2-cyclopropyl-1-[(2S)-4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrol-1-yl]ethan-1-one
Show/Hide
|
C21H20F2N2O
|
1
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| 1 |
IC50 = 6500 nM
|
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CP0812569
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(4-formatemethylphenylprop-2-en-1-amine Hydrochloride
Show/Hide
|
C22H26ClNO3
|
1
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| 1 |
IC50 = 6500 nM
|
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CP0439897
|
4-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
|
C23H26N4O3
|
1
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| 1 |
IC50 = 6600 nM
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CP0156012
|
4-(4-methoxyphenyl)-4,4-diphenylbutan-1-amine
Show/Hide
|
C23H25NO
|
1
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| 1 |
IC50 = 6600 nM
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CP0282364
|
N-[1-[2-(tert-butylcarbamoylamino)ethyl]pyrrolidin-3-yl]-3,5-dichlorobenzamide
Show/Hide
|
C18H26Cl2N4O2
|
1
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| 1 |
IC50 = 6600 nM
|
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CP0527835
|
(2R)-4-ethyl-9-[2-(3-fluorophenyl)ethyl]-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H27FN2O2
|
1
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| 1 |
IC50 = 6600 nM
|
|
|
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CP0552477
|
(2R)-2-ethyl-4-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H28N2O2
|
1
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| 1 |
IC50 = 6600 nM
|
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CP0816806
|
(E)-N-(Coumaran-5-methyl)-N-methyl-3-(naphthalen-2-yl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C23H24ClNO
|
1
|
| 1 |
IC50 = 6700 nM
|
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CP0558618
|
2-(4-fluorophenyl)-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide
Show/Hide
|
C20H21FN4O
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
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CP0122596
|
[2-(4,4-difluoropiperidin-1-yl)-5-methylsulfonylphenyl]-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
|
C23H22F3N5O3S
|
1
|
| 1 |
IC50 = 6700 nM
|
|
|
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CP0206668
|
4-amino-N-[(1S)-1-(4-chlorophenyl)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C20H23ClN6O
|
1
|
| 1 |
IC50 = 6747 nM
|
|
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CP0553633
|
4-N-[3-(dimethylamino)propyl]-6-(6-methoxypyridin-3-yl)-2-N-methylthieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C18H24N6OS
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
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CP0420341
|
[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-(3-phenylazetidin-1-yl)methanone
Show/Hide
|
C21H22F3NO5S
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
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CP0549543
|
N-[[4-(4-benzylpiperazin-1-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C26H33F3N4O2
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
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CP0367712
|
1-(2-morpholino-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C30H36F3N5O2
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
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CP0425937
|
[4-[2-fluoro-4-(trifluoromethyl)phenyl]piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C22H21F7N2O4S
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
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CP0065472
|
[5-amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(1H-indol-2-yl)methanone
Show/Hide
|
C20H16N6O
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
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CP0132279
|
[5-amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(6-methyl-1H-indol-2-yl)methanone
Show/Hide
|
C21H18N6O
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
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CP0543502
|
4-(4,4-difluoropiperidin-1-yl)-3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile
Show/Hide
|
C24H22F2N6O
|
1
|
| 1 |
IC50 = 6900 nM
|
|
|
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CP0014894
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3,5-diamino-6-(1-benzofuran-2-yl)-N-(diaminomethylidene)pyrazine-2-carboxamide
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C14H13N7O2
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1
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| 1 |
IC50 = 6900 nM
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CP0048096
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5-(3-benzylpyrrolidin-3-yl)-1-methyl-1H-indole
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C20H22N2
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1
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| 1 |
IC50 = 7000 nM
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CP0510255
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1-[(4-chlorophenyl)methyl]-5,6-dimethylbenzimidazole
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C16H15ClN2
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1
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| 1 |
IC50 = 7000 nM
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CP0570845
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US8975247, EBP144
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C19H18ClN3O
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1
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| 1 |
IC50 = 7000 nM
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CP0580071
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(1S)-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-(heptylamino)ethanol
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C20H24F6N2O
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1
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| 1 |
IC50 = 7000 nM
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CP0674054
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rac-1-(2-(Difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine
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C24H16F3N5
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1
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| 1 |
IC50 = 7200 nM
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CP0696874
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rac-4-Amino-N-[1-(4-chlorophenyl)ethyl]-1-(7H-pyrrolo[2,3-d]-pyrimidin-4-yl)piperidine-4-carboxamide
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C20H23ClN6O
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1
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| 1 |
IC50 = 7200 nM
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CP0537076
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N-[(3S,4S)-1-cyclohexyl-3-[[(1S)-2-hydroxy-1-phenylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
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C30H34F2N4O4
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1
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| 1 |
IC50 = 7200 nM
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CP0576834
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3-[4-[4-[5-butyl-4-[4-(4-chlorophenoxy)phenyl]-1,3-thiazol-2-yl]piperidin-1-yl]butyl]-1-methylindole-5-carbonitrile
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C38H41ClN4OS
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1
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| 1 |
IC50 = 7200 nM
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CP0035807
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Cocaine
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C17H21NO4
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1
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| 1 |
IC50 = 7244.36 nM
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CP0195830
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(2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexyl-N-(4-hydroxycyclohexyl)acetamide
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C27H30ClF2N3O2
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1
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| 1 |
IC50 = 7300 nM
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CP0425952
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1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C24H28N4O2
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1
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| 1 |
IC50 = 7300 nM
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CP0557191
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6-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-1,4-benzoxazin-3-one
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C27H27FN4O5
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1
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| 1 |
IC50 = 7300 nM
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CP0431389
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1-(((1S,2R)-2-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
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C25H33F3N4O2
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1
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| 1 |
IC50 = 7330 nM
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CP0569727
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N-[4-[[2-[2-(1,1-difluoroethyl)-4,5-difluorophenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]phenyl]-1-(3-fluoropropyl)azetidin-3-amine
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C29H25F5N4OS
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1
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| 1 |
IC50 = 7400 nM
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CP0133950
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6-tert-butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine
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C20H19FN4O2S
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1
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| 1 |
IC50 = 7445 nM
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CP0517263
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methyl 4-[4-[7-amino-5-[(1,2,2,6,6-pentamethylpiperidin-4-yl)amino]-6-phenylpyrazolo[1,5-a]pyrimidin-3-yl]benzoyl]piperazine-1-carboxylate
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C35H44N8O3
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1
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| 1 |
IC50 = 7500 nM
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CP0003551
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N-(1-methylindol-5-yl)-2-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-2-oxoacetamide
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C23H26N4O2
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1
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| 1 |
IC50 = 7500 nM
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CP0051342
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4-[[(2S)-2-[2-(4-chlorophenyl)-5,6-difluorobenzimidazol-1-yl]-2-cyclohexylacetyl]amino]cyclohexane-1-carboxylic acid
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C28H30ClF2N3O3
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1
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| 1 |
IC50 = 7600 nM
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CP0224462
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4-[3-(3-methoxyphenyl)phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
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C18H20N2OS
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1
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| 1 |
IC50 = 7600 nM
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CP0573935
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5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[3-fluoro-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
Show/Hide
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C29H35F3N6O3
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1
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| 1 |
IC50 = 7600 nM
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CP0538858
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2-(3-fluorophenyl)-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide
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C20H21FN4O
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1
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| 1 |
IC50 = 7700 nM
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CP0062495
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(Z)-2-butenedioic acid;2-(2,2-dicyclohexylethyl)piperidine
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C19H35N
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1
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| 1 |
IC50 = 7762.47 nM
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CP0234117
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(S)-3-chloro-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)benzoic acid
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C28H23Cl2F2N3O3
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1
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| 1 |
IC50 = 7800 nM
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CP0435319
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4-[[4-amino-6-[3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2-yl)-2-(hydroxymethyl)phenyl]-1,3,5-triazin-2-yl]amino]-1-ethylpyrrole-2-carbonitrile
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C29H25FN8O2
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1
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| 1 |
IC50 = 7800 nM
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CP0877254
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2-((diethylamino)methyl)-4-(3-(4-(methylsulfinyl)phenyl)imidazo[1,2-b]pyridazin-6-ylamino)phenol
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C24H27N5O2S
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1
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| 1 |
IC50 = 7830 nM
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CP0949178
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3-(4-(methylsulfinyl)phenyl)-N-(pyrazin-2-yl)imidazo[1,2-b]pyridazin-6-amine
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C17H14N6OS
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1
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| 1 |
IC50 = 7840 nM
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CP0439898
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8-fluoro-1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
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C24H27FN4O2
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1
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| 1 |
IC50 = 7900 nM
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CP0314178
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(3S)-7-fluoro-3-(4-fluoro-3-pyrimidin-5-ylphenyl)-3-[2-(trifluoromethyl)pyridin-4-yl]isoindol-1-amine
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C24H14F5N5
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1
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| 1 |
IC50 = 7900 nM
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CP0552983
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1-[4-[3-[4-amino-5-(3-amino-4-chlorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl]piperazin-1-yl]ethanone
Show/Hide
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C22H26ClN7O
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2
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| 1 |
IC50 = 7900 nM
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| 2 |
IC50 = 19000 nM
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CP0485353
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4-benzyl-4-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
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C30H35F3N4O2
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1
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| 1 |
IC50 = 7930 nM
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CP0076412
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3-pyridin-3-yl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
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C21H19F3N4O3
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1
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| 1 |
IC50 = 7943.28 nM
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CP0377579
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5-methyl-N-[(3S)-5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]-2-phenyltriazole-4-carboxamide
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C24H28N6O2
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1
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| 1 |
IC50 = 7943.28 nM
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CP0416295
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N-[(3S)-5-(2-methoxypyrimidin-5-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
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C22H19F3N4O4
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1
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| 1 |
IC50 = 7943.28 nM
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CP0452262
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N-[(3S)-5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]-4-(trifluoromethoxy)benzamide
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C22H24F3N3O3
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1
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| 1 |
IC50 = 7943.28 nM
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CP0452263
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N-[(3S)-5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
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C22H25F3N4O3
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1
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| 1 |
IC50 = 7943.28 nM
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CP0084804
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6-[[(3R,4R)-3-aminooxan-4-yl]amino]-4-[(5-fluoro-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
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C18H24FN7O2
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1
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| 1 |
IC50 = 7943.28 nM
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CP0124831
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-(6,7-dihydro-5H-cyclopenta[b]pyridin-2-ylamino)pyridazine-3-carboxamide
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C19H25N7O
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1
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| 1 |
IC50 = 7943.28 nM
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CP0136868
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6-(2-aminoethylamino)-4-[(5-fluoro-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
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C15H20FN7O
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1
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| 1 |
IC50 = 7943.28 nM
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CP0416261
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
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C19H27N7O
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1
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| 1 |
IC50 = 7943.28 nM
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CP0002211
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N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
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C22H27FN4O2
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1
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| 1 |
IC50 = 7943.28 nM
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CP0476245
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N-[(1S,2S)-1-[3-(dimethylamino)propanoylamino]-2,3-dihydro-1H-inden-2-yl]-5-methyl-1H-indole-2-carboxamide
Show/Hide
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C24H28N4O2
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1
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| 1 |
IC50 = 7943.28 nM
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CP0318875
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5-[3-(3-methoxyphenyl)phenyl]-5-methyl-2,6-dihydro-1,4-oxazin-3-amine
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C18H20N2O2
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1
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| 1 |
IC50 = 8000 nM
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CP0323255
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4-[(3S,4S)-3-(aminomethyl)-4-(5-chloropyridin-2-yl)sulfonyl-3-hydroxypyrrolidin-1-yl]sulfonyl-3-chlorobenzonitrile
Show/Hide
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C17H16Cl2N4O5S2
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1
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| 1 |
IC50 = 8000 nM
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CP0340178
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4-[(3R,4S)-3-(aminomethyl)-4-(5-chloropyridin-2-yl)sulfonyl-3-hydroxypyrrolidin-1-yl]sulfonyl-3-chlorobenzonitrile
Show/Hide
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C17H16Cl2N4O5S2
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1
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| 1 |
IC50 = 8000 nM
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CP0317450
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2-[(2R)-4-(2-fluoro-4-methylsulfonylphenyl)-2-methylpiperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyrimidine-4-carboxamide
Show/Hide
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C27H34FN5O4S
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1
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| 1 |
IC50 = 8000 nM
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CP0531332
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(8S)-N-methyl-N-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]methyl]-5,6,7,8-tetrahydroquinolin-8-amine
Show/Hide
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C21H30N6
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1
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| 1 |
IC50 = 8000 nM
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CP0761533
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3-(1H-indol-7-ylamino)-5-((1R,2S)-2-aminocyclohexylamino)pyrazine-2-carboxamide
Show/Hide
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C19H23N7O
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1
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| 1 |
IC50 = 8100 nM
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CP0549536
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[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[2-[(2-methylpropan-2-yl)oxy]-5-methylsulfonylphenyl]methanone
Show/Hide
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C23H24FN3O4S
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1
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| 1 |
IC50 = 8100 nM
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CP0418436
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7-methyl-2-[(7-methylimidazo[1,2-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one
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C19H21N7O2
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1
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| 1 |
IC50 = 8100 nM
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CP0573936
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5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[5-methoxy-6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyridin-3-yl]pyrimidin-2-amine
Show/Hide
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C29H37F2N7O4
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1
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| 1 |
IC50 = 8100 nM
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CP0086802
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1-(1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-[2-(2-methoxyphenyl)ethylamino]ethanone
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C26H34N2O2
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1
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| 1 |
IC50 = 8300 nM
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CP0262055
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N-[3-[(2S,5R)-6-amino-5-ethylsulfonyl-2-(fluoromethyl)-5-methyl-3,4-dihydropyridin-2-yl]-4-fluorophenyl]-2,2-difluoro-[1,3]dioxolo[4,5-c]pyridine-6-carboxamide
Show/Hide
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C22H22F4N4O5S
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1
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| 1 |
IC50 = 8300 nM
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CP0015167
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2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-N,N-dimethyl-7,8-dihydro-5H-1,6-naphthyridine-6-carboxamide
Show/Hide
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C22H23FN4O3
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1
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| 1 |
IC50 = 8300 nM
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CP0158438
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6-tert-butylsulfonyl-N-(1H-pyrazol-5-yl)quinolin-4-amine
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C16H18N4O2S
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1
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| 1 |
IC50 = 8305 nM
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CP0285118
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6-chloro-N-[(3R)-3-[4-[(2-methoxyacetyl)-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
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C25H35ClN4O3S
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1
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| 1 |
IC50 = 8400 nM
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CP0214767
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4-[[(2S,3S,6R)-2,6-dimethylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C21H24N4OS
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1
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| 1 |
IC50 = 8400 nM
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CP0905312
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3,6-bis(3-(methylsulfinyl)phenyl)imidazo[1,2-b]pyridazine
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C20H17N3O2S2
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1
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| 1 |
IC50 = 8450 nM
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CP0279376
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5-[(1R)-3-amino-1-[3-(2-cyclopropylethynyl)phenyl]-4-fluoroisoindol-1-yl]-1-ethyl-3-methylpyridin-2-one
Show/Hide
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C27H24FN3O
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1
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| 1 |
IC50 = 8500 nM
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CP0556824
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4-N-[3-(dimethylamino)propyl]-2-N-methyl-6-phenylthieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
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C18H23N5S
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1
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| 1 |
IC50 = 8500 nM
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CP0121931
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-2-[3-(triazol-2-yl)anilino]pyridine-3-carboxamide
Show/Hide
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C20H24N8O
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1
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| 1 |
IC50 = 8500 nM
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CP0318773
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4-(4-methoxyphenyl)-2-methyl-4-(3-pyrimidin-5-ylphenyl)imidazo[1,5-b]pyrazol-6-amine
Show/Hide
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C23H20N6O
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1
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| 1 |
IC50 = 8600 nM
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CP0093554
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BIIB-057
Show/Hide
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C19H23N9O
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1
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| 1 |
IC50 = 8600 nM
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CP0065543
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US10689705, Compound 7
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C26H25F2N7O
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1
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| 1 |
IC50 = 8600 nM
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CP0168851
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6-tert-butylsulfonyl-N-(4,5,6,7-tetrahydro-1H-indazol-3-yl)quinolin-4-amine
Show/Hide
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C20H24N4O2S
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1
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| 1 |
IC50 = 8635 nM
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CP0688798
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(2E,4E,6E)-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-N-methyl-7-(4-(trifluoromethyl)phenyl)hepta-2,4,6-trien-1-amine Hydrochloride
Show/Hide
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C24H25ClF3NO2
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1
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| 1 |
IC50 = 8700 nM
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CP0496462
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N-[[4-[4-[2-(2,2,2-trifluoroethoxy)ethyl]piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C23H32F6N4O3
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1
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| 1 |
IC50 = 8700 nM
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CP0555362
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US8975247, EBP461
Show/Hide
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C24H24ClN3
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1
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| 1 |
IC50 = 8800 nM
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CP0429773
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4-(3-fluorophenyl)-3-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile
Show/Hide
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C24H15F2N5O
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1
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| 1 |
IC50 = 8800 nM
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CP0572643
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2-imidazo[4,5-b]pyridin-3-yl-1-[(2R)-4-[4-(4-methoxyphenyl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C24H23F3N6O2S
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1
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| 1 |
IC50 = 8800 nM
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CP0568809
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(1S)-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-(pentylamino)ethanol
Show/Hide
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C18H20F6N2O
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1
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| 1 |
IC50 = 8800 nM
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CP0543586
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2-imidazo[4,5-b]pyridin-3-yl-1-[(2R)-4-[4-(6-methoxypyridin-3-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C23H22F3N7O2S
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1
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| 1 |
IC50 = 8900 nM
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CP0039741
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(+)-5-(3-benzylpyrrolidin-3-yl)-1H-indole
Show/Hide
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C19H20N2
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1
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| 1 |
IC50 = 9000 nM
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CP0039769
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5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole
Show/Hide
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C19H19FN2
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1
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| 1 |
IC50 = 9000 nM
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CP0110257
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5-[3-(3-methoxyphenyl)phenyl]-5-methyl-2,6-dihydro-1,4-thiazin-3-amine
Show/Hide
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C18H20N2OS
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0318714
|
5-fluoro-2-methyl-2-(3-pyrimidin-5-ylphenyl)-1,3-benzoxazin-4-amine
Show/Hide
|
C19H15FN4O
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0124822
|
US9315520, 7
Show/Hide
|
C17H18ClN5O2S2
|
1
|
| 1 |
IC50 = 9000 nM
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|
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CP0343336
|
4-[5-(2-chloro-6-fluoroanilino)pyrazolo[3,4-b]pyridin-1-yl]-N-methylthiophene-2-carboxamide
Show/Hide
|
C18H13ClFN5OS
|
1
|
| 1 |
IC50 = 9000 nM
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|
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CP0128301
|
4-amino-N-[(1R)-1-(4-chlorophenyl)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C20H23ClN6O
|
1
|
| 1 |
IC50 = 9092 nM
|
|
|
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CP0438690
|
(E)-N-Hydroxy-3-{4-[2-(2-methyl-1H-indol-3-ylmethyl)piperidin-1-ylmethyl]phenyl}acrylamide
Show/Hide
|
C25H29N3O2
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
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CP0014182
|
[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-morpholin-4-ylmethanone
Show/Hide
|
C24H25FN4O4
|
1
|
| 1 |
IC50 = 9100 nM
|
|
|
|
CP0102831
|
2-[3-(3-methoxyphenyl)phenyl]-2-methyl-5H-1,3-thiazol-4-amine
Show/Hide
|
C17H18N2OS
|
1
|
| 1 |
IC50 = 9200 nM
|
|
|
|
CP0425958
|
1-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethoxy]-3,4-dihydroquinolin-2-one
Show/Hide
|
C23H26N4O3
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
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CP0085485
|
4-amino-N-[1-(4-chlorophenyl)-3-methoxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C22H27ClN6O2
|
1
|
| 1 |
IC50 = 9369 nM
|
|
|
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CP0369776
|
2-[3-[4-amino-6-[(1-cyclopropylpyrazol-4-yl)amino]-1,3,5-triazin-2-yl]-2-(hydroxymethyl)phenyl]-6-cyclopropyl-8-fluoroisoquinolin-1-one
Show/Hide
|
C28H25FN8O2
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
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CP0496459
|
N-[[4-[4-[2-(2-methylpropoxy)ethyl]piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C25H39F3N4O3
|
1
|
| 1 |
IC50 = 9500 nM
|
|
|
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CP0462103
|
methyl 2-[(4-cyclopentyloxyphenyl)sulfonylamino]-3-(1H-indol-3-yl)propanoate
Show/Hide
|
C23H26N2O5S
|
1
|
| 1 |
IC50 = 9560 nM
|
|
|
|
CP0097508
|
US9315520, 45
Show/Hide
|
C19H21F2N5O3S2
|
1
|
| 1 |
IC50 = 9600 nM
|
|
|
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CP0558456
|
N-[(3S,4S)-1-cyclopentyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C28H30F2N6O3
|
1
|
| 1 |
IC50 = 9600 nM
|
|
|
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CP0569061
|
7-methyl-9-[(3R)-1-methylpyrrolidin-3-yl]-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 = 9600 nM
|
|
|
|
CP0550188
|
7-methyl-9-(1-methylpiperidin-4-yl)-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
IC50 = 9700 nM
|
|
|
|
CP0533059
|
(E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-1-ylmethyl]-3-chlorophenyl}-N-hydroxyacrylamide
Show/Hide
|
C27H32ClN3O2
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0190427
|
4-[5-[[4-[(5R)-5-(3-chlorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]-6-methylpyridin-2-yl]oxybenzoic acid
Show/Hide
|
C33H37ClN4O5
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0390884
|
[2-(cyclopropylmethoxy)-5-methylsulfonylphenyl]-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
|
C23H22FN3O4S
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0451121
|
4-chloro-N-[(1R)-1-[(1R,5S)-3-(6-fluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H23ClFN3O
|
1
|
| 1 |
IC50 = 9900 nM
|
|
|
|
CP0162544
|
5-tert-Butyl-1-(4-fluoro-phenyl)-1H-indole
Show/Hide
|
C18H18FN
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0224890
|
1-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethanone
Show/Hide
|
C16H11ClFNO
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0297102
|
5-Chloro-1-(4-fluoro-phenyl)-3-isopropyl-1H-indole
Show/Hide
|
C17H15ClFN
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0068493
|
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
Show/Hide
|
C25H29I2NO3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0072374
|
BAY-E-5009
Show/Hide
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C18H20N2O6
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0048094
|
5-(3-benzylpyrrolidin-3-yl)-N-methyl-1H-indole-2-carboxamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0048099
|
1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane
Show/Hide
|
C11H11Cl2N
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0211853
|
5-(3-benzylpyrrolidin-3-yl)-1H-indole-2-carboxamide
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0427238
|
1-(2-(pyrrolidine-1-carbonyl)piperidin-1-yl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
|
C29H37F3N4O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0454254
|
N-(2-pyridin-2-ylethyl)-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C25H27F3N4O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0063692
|
2-(1-(4-chloro-3,5-diethoxybenzyl)piperidin-4-ylamino)benzo[d]oxazole-5-carboxylic acid
Show/Hide
|
C24H28ClN3O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0106411
|
2-(1-(4-chloro-3-ethoxybenzyl)piperidin-4-ylamino)benzo[d]oxazole-6-carboxylic acid
Show/Hide
|
C22H24ClN3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0401874
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Show/Hide
|
C22H22F6N2O4S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0425932
|
[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C21H20ClF6N3O4S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0124784
|
2-(2-oxo-3-phenyl-1-oxa-3-azaspiro[4.5]decan-8-yl)-3H-benzimidazole-5-carbonitrile
Show/Hide
|
C22H20N4O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0048148
|
4-[[(2S)-2-cyclohexyl-2-[2-(2,6-dimethoxypyridin-3-yl)-5,6-difluorobenzimidazol-1-yl]acetyl]amino]cyclohexane-1-carboxylic acid
Show/Hide
|
C29H34F2N4O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0048152
|
(S)-2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexyl-N-(2-fluoro-4-(1H-tetrazol-5-yl)phenyl)acetamide
Show/Hide
|
C28H23ClF3N7O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0076201
|
N-[(3S)-5-[6-(hydroxymethyl)pyridin-3-yl]-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C23H20F3N3O4
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0416296
|
N-[(3S)-5-(2-methylpyrimidin-5-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C22H19F3N4O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0493834
|
2-(2,4-dimethylphenyl)-5-methyl-N-[(3S)-5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]triazole-4-carboxamide
Show/Hide
|
C26H32N6O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0105037
|
2-(4-methoxyphenyl)-2-(3-pyridin-3-ylphenyl)-5H-1,3-thiazol-4-amine
Show/Hide
|
C21H19N3OS
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0055664
|
2-(4-methylpiperazin-1-yl)-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
Show/Hide
|
C32H32N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0218531
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(6-methylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C17H23N7O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0411804
|
6-(2-aminoethylamino)-4-[(5-methoxy-6-propylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C16H23N7O2
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0245877
|
5-[[(1R,2S)-2-aminocyclohexyl]amino]-3-[3-(triazol-2-yl)anilino]pyrazine-2-carboxamide
Show/Hide
|
C19H23N9O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0141502
|
4-[2-(5-methyl-1-naphthalen-2-ylpyrazol-3-yl)oxyethyl]morpholine
Show/Hide
|
C20H23N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0381939
|
1-(3-fluorophenyl)-N-[2-(1,4-oxazepan-4-yl)ethyl]triazol-4-amine
Show/Hide
|
C15H20FN5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0381940
|
1-benzyl-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C16H23N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0381942
|
1-(1-adamantyl)-N-ethyl-N-(2-morpholin-4-ylethyl)triazol-4-amine
Show/Hide
|
C20H33N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0398163
|
1-(3,4-difluorophenyl)-N-[2-(4,4-difluoropiperidin-1-yl)ethyl]triazol-4-amine
Show/Hide
|
C15H17F4N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0398165
|
1-[(3,4-difluorophenyl)methyl]-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C16H21F2N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0400671
|
N-[2-(azepan-1-yl)ethyl]-1-benzyltriazol-4-amine
Show/Hide
|
C17H25N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0441698
|
1-[(3,4-dichlorophenyl)methyl]-N-(2-morpholin-4-ylethyl)triazol-4-amine
Show/Hide
|
C15H19Cl2N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0456017
|
1-(1-adamantyl)-N-(2-morpholin-4-ylethyl)triazol-4-amine
Show/Hide
|
C18H29N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472330
|
1-[(3,4-difluorophenyl)methyl]-N-[2-(4,4-difluoropiperidin-1-yl)ethyl]triazol-4-amine
Show/Hide
|
C16H19F4N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0472331
|
N-[2-(4,4-difluoropiperidin-1-yl)ethyl]-1-[(4-fluorophenyl)methyl]triazol-4-amine
Show/Hide
|
C16H20F3N5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0518476
|
1-(3,4-dichlorophenyl)-N-(2-morpholin-4-ylethyl)triazol-4-amine
Show/Hide
|
C14H17Cl2N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0518479
|
1-[(4-fluorophenyl)methyl]-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C16H22FN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531838
|
1-[(3-fluorophenyl)methyl]-N-(2-piperidin-1-ylethyl)triazol-4-amine
Show/Hide
|
C16H22FN5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0188530
|
6-(4-chlorophenyl)-3-[6-(4-hydroxypiperidin-1-yl)pyridin-3-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one
Show/Hide
|
C22H20ClN5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0475392
|
US8975247, EBP462
Show/Hide
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C24H22ClN3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0530602
|
US8975247, EBP468
Show/Hide
|
C23H27ClN2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0531768
|
US8975247, EBP475
Show/Hide
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C22H19ClN2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0536271
|
US8975247, EBP376
Show/Hide
|
C22H19ClN2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0566391
|
US8975247, EBP325
Show/Hide
|
C22H25ClN2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0376862
|
5-(4-bromophenyl)-3-(4-fluorophenyl)-N-phenyl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H17BrFN3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0459413
|
5-(4-bromophenyl)-N-(3-fluorophenyl)-3-(4-fluorophenyl)-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C22H16BrF2N3O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0061346
|
US8829199, 74
Show/Hide
|
C26H20N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0065546
|
US10689705, Compound 46
Show/Hide
|
C21H18N6O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0065547
|
[5-amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-[5-(morpholin-4-ylmethyl)-1H-indol-2-yl]methanone
Show/Hide
|
C25H25N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0132074
|
US8829199, 132
Show/Hide
|
C25H25N7O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0202564
|
[5-amino-1-(2-methyl-3H-benzimidazol-5-yl)pyrazol-4-yl]-(6-bromo-1H-indol-2-yl)methanone
Show/Hide
|
C20H15BrN6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0392805
|
5-fluoro-N-[(1S,2S)-1-[[(3S)-pyrrolidine-3-carbonyl]amino]-2,3-dihydro-1H-inden-2-yl]-1H-indole-2-carboxamide
Show/Hide
|
C23H23FN4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0075337
|
(2-phenyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)-[5-propan-2-ylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
|
C24H24F3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0148784
|
3-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile
Show/Hide
|
C21H15F4N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0148785
|
[2-(4,4-difluoropiperidin-1-yl)-5-methylsulfonylphenyl]-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
|
C24H25F2N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0148786
|
[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
|
C22H21F3N4O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0148793
|
[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-(2-phenyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)methanone
Show/Hide
|
C22H20F3N3O4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0149053
|
3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-propan-2-yloxybenzonitrile
Show/Hide
|
C22H21N5O2
|
2
|
| 1 |
IC50 = 10000 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
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CP0199188
|
[5-ethylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
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C22H20F4N4O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0199190
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[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C22H19F4N3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0364500
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4-(cyclopropylmethoxy)-3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile
Show/Hide
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C23H21N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0364501
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3-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile
Show/Hide
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C22H16F4N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0390883
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3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile
Show/Hide
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C22H18F3N5O2
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1
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| 1 |
IC50 = 10000 nM
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CP0390885
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[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-(5-methylsulfonyl-2-propan-2-yloxyphenyl)methanone
Show/Hide
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C22H22FN3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0390886
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[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C21H18F4N4O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0390888
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[5-ethylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[2-(2-fluorophenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
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C23H21F4N3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0390890
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(2-cyclopentyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C21H24F3N3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0390891
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[2-(3-fluorophenyl)-5-methylsulfonylphenyl]-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
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C24H18F2N4O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0390892
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3-(2-cyclopentyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl)-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile
Show/Hide
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C21H21F3N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0414908
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4-(3-fluorophenyl)-3-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]benzonitrile
Show/Hide
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C25H18FN5O
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1
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| 1 |
IC50 = 10000 nM
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CP0429685
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3-(2-phenyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl)-4-propan-2-yloxybenzonitrile
Show/Hide
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C22H20N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0429771
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[5-ethylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
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C23H23F3N4O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0429772
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3-[2-(5-fluoropyridin-3-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-propan-2-yloxybenzonitrile
Show/Hide
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C21H18FN5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0464397
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[2-(3-methylphenyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C23H22F3N3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0545831
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[2-(3-fluorophenyl)-5-methylsulfonylphenyl]-[2-(2-methylpyridin-4-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]methanone
Show/Hide
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C25H21FN4O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0403072
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7,8-dichloro-1-(furan-2-ylmethylamino)-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
Show/Hide
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C18H9Cl2F3N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0440595
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7,8-dichloro-1-(thiophen-2-ylmethylamino)-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
Show/Hide
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C18H9Cl2F3N4S
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1
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| 1 |
IC50 > 10000 nM
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CP0440596
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7,8-dichloro-1-[(2-fluorophenyl)methylamino]-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
Show/Hide
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C20H10Cl2F4N4
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1
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| 1 |
IC50 > 10000 nM
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CP0440597
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7,8-dichloro-1-[(3-fluorophenyl)methylamino]-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
Show/Hide
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C20H10Cl2F4N4
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1
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| 1 |
IC50 > 10000 nM
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CP0491758
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1-[4-(trifluoromethoxy)anilino]-3-(trifluoromethyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
Show/Hide
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C20H10F6N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0032823
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3-chloro-4-[(3R,4S)-4-(4-chlorophenyl)sulfonyl-3-hydroxy-3-(hydroxymethyl)pyrrolidin-1-yl]sulfonylbenzonitrile
Show/Hide
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C18H16Cl2N2O6S2
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1
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| 1 |
IC50 > 10000 nM
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CP0121507
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[3-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]azetidin-1-yl]-[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C21H19ClF6N2O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0420359
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3-[2-(5-fluoropyridin-2-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-2-methoxy-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile
Show/Hide
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C22H17F4N5O3
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0420360
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2-chloro-3-[2-(5-fluoropyridin-2-yl)-4,6-dihydropyrrolo[3,4-c]pyrazole-5-carbonyl]-4-[(2S)-1,1,1-trifluoropropan-2-yl]oxybenzonitrile
Show/Hide
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C21H14ClF4N5O2
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1
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| 1 |
IC50 > 10000 nM
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CP0473005
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[3-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]azetidin-1-yl]-[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C21H19F7N2O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0525818
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[2-(5-fluoropyridin-2-yl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl]-[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone
Show/Hide
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C22H20F4N4O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0525820
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[2-methoxy-3-methylsulfonyl-6-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]-[3-[5-(trifluoromethyl)pyridin-2-yl]azetidin-1-yl]methanone
Show/Hide
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C21H20F6N2O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0125925
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OXYCODONE
Show/Hide
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C18H21NO4
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1
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| 1 |
IC50 > 10000 nM
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CP0252205
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(2R)-9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0324869
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8-[2-(2-fluorophenyl)ethyl]-12-[2-(trifluoromethyl)pyridin-3-yl]-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
Show/Hide
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C24H25F4N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0426234
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(2R)-2,4-dimethyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C18H26N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0426235
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(2S)-9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0426240
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(2R)-9-[2-(2,3-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0471523
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4-[2-(2-fluorophenyl)ethyl]-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C25H31FN2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0472861
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2,4-dimethyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C18H26N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0424560
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1-[4-[2-[[1-(3,4-dichlorophenyl)-5-methylpyrazol-3-yl]methoxy]ethyl]piperazin-1-yl]ethanone
Show/Hide
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C19H24Cl2N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0553115
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1-[4-[2-[[1-(3,4-difluorophenyl)-5-methylpyrazol-3-yl]methoxy]ethyl]piperazin-1-yl]ethanone
Show/Hide
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C19H24F2N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0559035
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1-[4-[2-[[1-(3,4-difluorophenyl)pyrazol-3-yl]methoxy]ethyl]piperazin-1-yl]ethanone;hydrochloride
Show/Hide
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C18H23ClF2N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0444872
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5-(2,4-difluorophenyl)-N-[(3S,4S)-1-(2-methoxyethyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C26H28F2N6O4
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1
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| 1 |
IC50 > 10000 nM
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CP0444886
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N-[(3S,4S)-3-(benzylcarbamoyl)-1-cyclohexylpiperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C29H32F2N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0517205
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N-[(3S,4S)-1-acetyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C25H24F2N6O4
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1
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| 1 |
IC50 > 10000 nM
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CP0517217
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5-(2,4-difluorophenyl)-N-[(3S,4S)-1-methyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C24H24F2N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0538277
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N-[(3S,4S)-1-cyclohexyl-3-[(1-pyridin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C30H33F2N5O3
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1
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| 1 |
IC50 > 10000 nM
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CP0551804
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N-[(3S,4S)-1-cyclohexyl-3-[[(1R)-1-phenylethyl]carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C30H34F2N4O3
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1
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| 1 |
IC50 > 10000 nM
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CP0552289
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N-[(3S,4S)-1-cyclopropyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C26H26F2N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0554598
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5-(2,4-difluorophenyl)-N-[(3S,4S)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C23H22F2N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0554599
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5-(2,4-difluorophenyl)-N-[(3S,4S)-1-propan-2-yl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C26H28F2N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0558270
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5-(2,4-difluorophenyl)-N-[(3S,4S)-1-[(1-fluorocyclopropyl)methyl]-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C27H27F3N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0560994
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N-[(3S,4S)-1-cyclobutyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C27H28F2N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0572606
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5-(2,4-difluorophenyl)-N-[(3S,4S)-1-ethyl-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C25H26F2N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0574402
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5-(2,4-difluorophenyl)-N-[(3S,4S)-1-(3-fluoropropyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
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C26H27F3N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0574635
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N-[(3S,4S)-1-(3,3-difluorocyclobutyl)-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-5-(2,4-difluorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
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C27H26F4N6O3
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1
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| 1 |
IC50 > 10000 nM
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CP0219639
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7-fluoro-2-[(4-hydroxycyclohexyl)amino]-5-methylpyrido[4,3-b][1,4]benzoxazepin-6-one
Show/Hide
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C19H20FN3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0219640
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2-[(4-hydroxycyclohexyl)amino]-5-methylpyrido[4,3-b][1,4]benzoxazepin-6-one
Show/Hide
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C19H21N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0555421
|
10-fluoro-2-[(4-hydroxycyclohexyl)amino]-5-methylpyrido[4,3-b][1,4]benzoxazepin-6-one
Show/Hide
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C19H20FN3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0562918
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7,10-difluoro-2-[(4-hydroxycyclohexyl)amino]-5-methylpyrido[4,3-b][1,4]benzoxazepin-6-one
Show/Hide
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C19H19F2N3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0572635
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2-[(4-hydroxycyclohexyl)amino]-10-methoxy-5-methylpyrido[4,3-b][1,4]benzoxazepin-6-one
Show/Hide
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C20H23N3O4
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1
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| 1 |
IC50 > 10000 nM
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CP0573411
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10-chloro-2-[(4-hydroxycyclohexyl)amino]-5-methylpyrido[4,3-b][1,4]benzoxazepin-6-one
Show/Hide
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C19H20ClN3O3
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1
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| 1 |
IC50 > 10000 nM
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CP0004748
|
N-Cyclopropyl-2-[2-oxo-6-[3-(trifluoromethyl)phenyl]-3H-imidazo[4,5- b]pyridin-1-yl]acetamide
Show/Hide
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C18H15F3N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0013612
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2-[6-(4-Fluoro-3-methyl-phenyl)pyrrolo[3,2-b]pyridin-1-yl]-N,N-
Show/Hide
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C18H18FN3O
|
1
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| 1 |
IC50 > 10000 nM
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CP0015127
|
N,N-Dimethyl-2-[6-[5-(trifluoromethyl)-2-thienyl]pyrrolo[3,2-
Show/Hide
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C16H14F3N3OS
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1
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| 1 |
IC50 > 10000 nM
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CP0466216
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N,N-Dimethyl-2-[3-methyl-6-(4-methyl-2-thienyl)-2-oxo-imidazo[4,5- b]pyridin-1-yl]acetamide
Show/Hide
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C16H18N4O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0487650
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1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-3-methyl-6-(5-methyl-2- thienyl)imidazo[4,5-b]pyridin-2-one
Show/Hide
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C17H18N4O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0487651
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N,N-Dimethyl-2-[3-methyl-2-oxo-6-[5-(trifluoromethyl)-2- thienyl]imidazo[4,5-b]pyridin-1-yl]acetamide
Show/Hide
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C16H15F3N4O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0487652
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1-[2-(3-Fluoroazetidin-1-yl)-2-oxo-ethyl]-3-methyl-6-[5-(trifluoromethyl)-2- thienyl]imidazo[4,5-b]pyridin-2-one
Show/Hide
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C17H14F4N4O2S
|
1
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| 1 |
IC50 > 10000 nM
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CP0487653
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1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-[5-(difluoromethyl)-2-thienyl]-3-methyl- imidazo[4,5-b]pyridin-2-one
Show/Hide
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C17H16F2N4O2S
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0487654
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1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-[4-(difluoromethyl)-2-thienyl]-3-methyl- imidazo[4,5-b]pyridin-2-one
Show/Hide
|
C17H16F2N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0566161
|
1-[2-(3-Fluoroazetidin-1-yl)-2-oxo-ethyl]-3-methyl-6-[3- (trifluoromethyl)phenyl]imidazo[4,5-b]pyridin-2-one
Show/Hide
|
C19H16F4N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0566162
|
1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-(5-cyclopropyl-2-thienyl)-3-methyl- imidazo[4,5-b]pyridin-2-one
Show/Hide
|
C19H20N4O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0568912
|
1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-3-methyl-6-[3- (trifluoromethyl)phenyl]imidazo[4,5-b]pyridin-2-one
Show/Hide
|
C19H17F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0578928
|
N,N-Dimethyl-2-[3-methyl-2-oxo-6-[3-(trifluoromethyl)phenyl]imidazo[4,5- b]pyridin-1-yl]acetamide
Show/Hide
|
C18H17F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0137438
|
4-[5-(2-chloro-6-fluoroanilino)-6-methylpyrazolo[3,4-b]pyridin-1-yl]-N-(oxetan-3-yl)thiophene-2-carboxamide
Show/Hide
|
C21H17ClFN5O2S
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0496454
|
N-[(4-piperazin-1-yloxan-4-yl)methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C19H27F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0496458
|
N-[[4-[4-(2-methylpropyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0496463
|
N-[[4-[4-(2-hydroxy-2-methylpropyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0549542
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(2-hydroxyphenyl)propanamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0549546
|
N-[[4-[4-(2-ethoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0568691
|
N-[[4-[4-(3-methoxypropyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569288
|
N-[[4-[4-(1-phenylethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C27H35F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0569685
|
N-[[4-(4-benzylpiperazin-1-yl)-1-methylpiperidin-4-yl]methyl]-N-phenylpropanamide
Show/Hide
|
C27H38N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0570045
|
N-[[4-(4-propylpiperazin-1-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C22H33F3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0574138
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(3-fluoropyridin-2-yl)propanamide
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0574140
|
N-[[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C24H37F3N4O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0543407
|
ASP-5878
Show/Hide
|
C18H19F2N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0574966
|
5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
Show/Hide
|
C31H40F2N6O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0014179
|
2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-6H-1,6-naphthyridin-5-one
Show/Hide
|
C19H16FN3O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0014188
|
[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-piperidin-1-ylmethanone
Show/Hide
|
C25H27FN4O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0014678
|
cyclobutyl-[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone
Show/Hide
|
C24H24FN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0015197
|
[2-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-pyrrolidin-1-ylmethanone
Show/Hide
|
C24H25FN4O3
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0123099
|
US8865706, 13
Show/Hide
|
C18H18F3N3O2S
|
1
|
| 1 |
IC50 = 10100 nM
|
|
|
|
CP0375176
|
N-(4-methoxyphenyl)-2-[3-[2-[(4-methoxyphenyl)sulfonylamino]ethyl]indol-1-yl]acetamide
Show/Hide
|
C26H27N3O5S
|
1
|
| 1 |
IC50 = 10230 nM
|
|
|
|
CP0571297
|
BMS-207147
Show/Hide
|
C22H17F2N5OS
|
1
|
| 1 |
IC50 = 10370 nM
|
|
|
|
CP0041757
|
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
IC50 = 10471.29 nM
|
|
|
|
CP0123103
|
US8962616, 1
Show/Hide
|
C16H15F2N3O2S
|
1
|
| 1 |
IC50 = 10600 nM
|
|
|
|
CP0211683
|
2-chloro-6-cyano-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4-methylpyridine-3-carboxamide
Show/Hide
|
C24H31ClN6O3S
|
1
|
| 1 |
IC50 = 10800 nM
|
|
|
|
CP0359960
|
4-phenyl-8-(3-phenyl-tetrahydro-pyran-3-yl)-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
IC50 > 11000 nM
|
|
|
|
CP0064497
|
3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine
Show/Hide
|
C19H19NS
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0114198
|
7-fluoro-3-(3-pyrimidin-5-ylphenyl)-3-[2-(trifluoromethyl)pyridin-4-yl]isoindol-1-amine
Show/Hide
|
C24H15F4N5
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0450546
|
6-methoxy-N-(oxan-4-ylmethyl)-3-[[4-(triazol-1-ylmethyl)naphthalene-1-carbonyl]amino]pyridine-2-carboxamide
Show/Hide
|
C27H28N6O4
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0318876
|
2-[3-(3-methoxyphenyl)phenyl]-2-methyl-5,6-dihydro-1,3-thiazin-4-amine
Show/Hide
|
C18H20N2OS
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0908800
|
N-[5-[[3-cyano-7-(cyclobutylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]acetamide
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0349958
|
N-[4-[1-(oxan-4-yl)pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl]morpholine-4-carboxamide
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0537172
|
5-(2,4-difluorophenyl)-N-[(3S,4S)-1-[(1-methylcyclopropyl)methyl]-3-[(1-pyrimidin-2-ylcyclopropyl)carbamoyl]piperidin-4-yl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C28H30F2N6O3
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0838670
|
(R)-3-((6-(2-Ethoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-3-phenylpropan-1-ol
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0534438
|
4-chloro-N-[(1R)-1-[(1S,5R)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
|
C23H22ClF2N3O
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0512077
|
2-amino-1-[2-(4-fluorophenyl)-3-(4-methylanilino)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
|
C21H22FN5O
|
1
|
| 1 |
IC50 = 11100 nM
|
|
|
|
CP0359991
|
(4S)-4-[2,4-difluoro-5-[[(1,1,1-trifluoro-2-methylpropan-2-yl)amino]methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
|
C16H20F5N3S
|
1
|
| 1 |
IC50 = 11200 nM
|
|
|
|
CP0682161
|
(E)-N-(Coumaran-5-methyl)-N-methyl-3-(4-biphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C25H26ClNO
|
1
|
| 1 |
IC50 = 11300 nM
|
|
|
|
CP0472051
|
N-[1H-imidazol-5-yl(phenyl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C29H30F3N5O
|
1
|
| 1 |
IC50 = 11400 nM
|
|
|
|
CP0406304
|
N-(4-chlorophenyl)-2-[3-[2-[(4-methoxyphenyl)sulfonylamino]ethyl]indol-1-yl]acetamide
Show/Hide
|
C25H24ClN3O4S
|
1
|
| 1 |
IC50 = 11490 nM
|
|
|
|
CP0545265
|
N-[4-[[2-[2-(1,1-difluoroethyl)-4-fluorophenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]-2-methoxyphenyl]-1-(3-fluoropropyl)azetidin-3-amine
Show/Hide
|
C30H28F4N4O2S
|
1
|
| 1 |
IC50 = 11500 nM
|
|
|
|
CP0428855
|
5-(3-chlorophenyl)-3-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,2,4-oxadiazole
Show/Hide
|
C18H15ClN6O2
|
1
|
| 1 |
IC50 = 11600 nM
|
|
|
|
CP0214763
|
2-phenyl-4-[[(3S)-piperidin-3-yl]amino]-1H-indole-7-carboxamide
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 11600 nM
|
|
|
|
CP0506347
|
N-[(1-hydroxycyclohexyl)methyl]-1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidine-4-carboxamide
Show/Hide
|
C25H32F3N3O2
|
1
|
| 1 |
IC50 = 11700 nM
|
|
|
|
CP0473760
|
3-(pyrrolidine-1-carbonyl)-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)piperidine-1-carboxamide
Show/Hide
|
C28H36F3N5O2
|
1
|
| 1 |
IC50 = 11700 nM
|
|
|
|
CP0032414
|
3-[(dipentylamino)methyl]-4-[[6-fluoro-8-(methylamino)-2-oxo-1H-quinoline-3-carbonyl]amino]benzoic acid
Show/Hide
|
C29H37FN4O4
|
1
|
| 1 |
IC50 = 11900 nM
|
|
|
|
CP0155467
|
2-[3-(3-methoxyphenyl)phenyl]-2-pyridin-4-yl-5H-1,3-thiazol-4-amine
Show/Hide
|
C21H19N3OS
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0479605
|
4-chloro-N-[2-[(1R,5S)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propan-2-yl]benzamide
Show/Hide
|
C23H22ClF2N3O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0264622
|
Anzemet Cinv
Show/Hide
|
C19H20N2O3
|
1
|
| 1 |
IC50 = 12022.64 nM
|
|
|
|
CP0731167
|
(2E,4E)-N-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)-N-methyl-5-(4-(trifluoromethyl)phenyl)penta-2,4-dien-1-amine Hydrochloride
Show/Hide
|
C22H23ClF3NO2
|
1
|
| 1 |
IC50 = 12100 nM
|
|
|
|
CP0255485
|
6-tert-butylsulfonyl-N-(5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-yl)quinolin-4-amine
Show/Hide
|
C19H18FN5O2S
|
1
|
| 1 |
IC50 = 12140 nM
|
|
|
|
CP0044706
|
(2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)prop-2-enamide
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
IC50 = 12200 nM
|
|
|
|
CP0120511
|
2-[3-(5-chloropyridin-3-yl)phenyl]-2-cyclopropyl-5-methylimidazol-4-amine
Show/Hide
|
C18H17ClN4
|
1
|
| 1 |
IC50 = 12400 nM
|
|
|
|
CP0067407
|
2-(2-oxo-3-pyridin-2-yl-1-oxa-3-azaspiro[4.5]decan-8-yl)-3H-benzimidazole-5-carbonitrile
Show/Hide
|
C21H19N5O2
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0062157
|
N-[(3S)-5-(5-methoxypyrazin-2-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxymethyl)pyridine-3-carboxamide
Show/Hide
|
C23H21F3N4O4
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0443557
|
N-[(3S)-5-(4-methylpiperazin-1-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(3,3,3-trifluoropropoxy)pyridine-3-carboxamide
Show/Hide
|
C23H27F3N4O3
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0452260
|
N-[(3S)-5-(2-methoxypyrimidin-5-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(3,3,3-trifluoropropoxy)pyridine-3-carboxamide
Show/Hide
|
C23H21F3N4O4
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0411750
|
6-(2-aminoethylamino)-4-[(5-methoxy-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C16H23N7O2
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0010652
|
ALFUZOSIN
Show/Hide
|
C19H27N5O4
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0521806
|
N-[(1R,2R)-1-[2-(dimethylamino)ethylcarbamoyl]-2,3-dihydro-1H-inden-2-yl]-1H-indole-2-carboxamide
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0367711
|
1-((1H-imidazol-2-yl)(phenyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C28H29F3N6O
|
1
|
| 1 |
IC50 = 12700 nM
|
|
|
|
CP0093918
|
5-[(4-benzylpiperazin-1-yl)methyl]-3-phenyl-1,2,4-oxadiazole
Show/Hide
|
C20H22N4O
|
1
|
| 1 |
IC50 = 12700 nM
|
|
|
|
CP0094025
|
(5-chloro-1-methylindol-2-yl)-[6-[(dimethylamino)methyl]-7-methyl-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Show/Hide
|
C23H26ClN3O
|
1
|
| 1 |
IC50 = 12900 nM
|
|
|
|
CP0443620
|
4-[3-[4-(2-oxo-1H-imidazo[4,5-b]pyridin-3-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
|
C22H25N5O3
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0428854
|
5-[[4-(1,3-benzothiazol-2-ylmethyl)piperazin-1-yl]methyl]-3-phenyl-1,2,4-oxadiazole
Show/Hide
|
C21H21N5OS
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0127886
|
N-[1-[2-(tert-butylcarbamoylamino)ethyl]azetidin-3-yl]-3,5-dichlorobenzamide
Show/Hide
|
C17H24Cl2N4O2
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0282370
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]piperidin-4-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C20H30Cl2N4O2
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0546734
|
1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-(3-methylpyrazol-1-yl)ethanone
Show/Hide
|
C21H24F3N7O2S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0550342
|
1-[(2R)-4-[4-(2-cyclopropylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-(3,5-dimethyl-1,2,4-triazol-1-yl)ethanone
Show/Hide
|
C22H25F3N8OS
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0567946
|
2-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
|
C22H26F3N7O2S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0572651
|
1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-imidazo[4,5-b]pyridin-3-ylethanone
Show/Hide
|
C23H23F3N8O2S
|
1
|
| 1 |
IC50 = 13000 nM
|
|
|
|
CP0553868
|
4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]-N-[4-(4-methylpiperazin-1-yl)phenyl]pyrimidin-2-amine
Show/Hide
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C29H32FN7S
|
1
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| 1 |
IC50 = 13200 nM
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CP0430639
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(E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)pyrrolidin-1-ylmethyl]phenyl}acrylamide
Show/Hide
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C23H25N3O2
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1
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| 1 |
IC50 = 13400 nM
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CP0175008
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2-amino-1-[3-(4-fluoroanilino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
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C22H23F2N5O
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1
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| 1 |
IC50 = 13400 nM
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CP0470583
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2-amino-1-[(8R)-3-(3-chloro-4-fluoroanilino)-2-(4-fluorophenyl)-8-propan-2-yl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
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C23H24ClF2N5O
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1
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| 1 |
IC50 = 13400 nM
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CP0490756
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(E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}-N-hydroxyacrylamide
Show/Hide
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C27H33N3O2
|
1
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| 1 |
IC50 = 13500 nM
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CP0165068
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2-[3-[4-amino-6-[[1-(1-cyclopropylethyl)pyrazol-4-yl]amino]-1,3,5-triazin-2-yl]-2-(hydroxymethyl)phenyl]-6-cyclopropyl-8-fluoroisoquinolin-1-one
Show/Hide
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C30H29FN8O2
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1
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| 1 |
IC50 = 13500 nM
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CP0095633
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(S,R)-MEFLOQUINE
Show/Hide
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C17H16F6N2O
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1
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| 1 |
IC50 = 13600 nM
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CP0210815
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(4S)-4-[5-[[[1-(difluoromethyl)cyclopropyl]amino]methyl]-2,4-difluorophenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C16H19F4N3S
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1
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| 1 |
IC50 = 13700 nM
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CP0123098
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US8865706, 22
Show/Hide
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C18H19F3N4OS
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1
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| 1 |
IC50 = 13800 nM
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CP0207108
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(4S)-4-[2,4-difluoro-5-[[[(2R)-1,1,1-trifluoropropan-2-yl]amino]methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C15H18F5N3S
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1
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| 1 |
IC50 = 13900 nM
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CP0883851
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4-phenyl-8-(4-phenyl-tetrahydro-pyran-4-yl)-2,8-diaza-spiro[4.5]decan-1-one
Show/Hide
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C25H31IN2O2
|
1
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| 1 |
IC50 > 14000 nM
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CP0534432
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1-(4-(pyrrolidine-1-carbonyl)piperazin-1-yl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
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C28H36F3N5O2
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1
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| 1 |
IC50 = 14000 nM
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CP0017037
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8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one
Show/Hide
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C25H19NO3S
|
1
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| 1 |
IC50 = 14000 nM
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CP0456623
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6-[methyl-[[6-(trifluoromethyl)pyridin-3-yl]methyl]amino]-N-(1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide
Show/Hide
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C15H12F3N7OS
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1
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| 1 |
IC50 = 14000 nM
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CP0559088
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7-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]isoquinolin-6-ol
Show/Hide
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C23H29N5O
|
1
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| 1 |
IC50 = 14000 nM
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CP0487664
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[4-[7-amino-5-[(1,2,2,6,6-pentamethylpiperidin-4-yl)amino]-6-phenylpyrazolo[1,5-a]pyrimidin-3-yl]phenyl]-(4-methylsulfonylpiperazin-1-yl)methanone
Show/Hide
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C34H44N8O3S
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1
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| 1 |
IC50 = 14000 nM
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CP0570604
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4-chloro-N-[(1S)-1-[(1R,5S)-3-(6-fluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H23ClFN3O
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1
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| 1 |
IC50 = 14000 nM
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CP0543408
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5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyridin-3-yl]pyrimidin-2-amine
Show/Hide
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C28H35F2N7O3
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1
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| 1 |
IC50 = 14000 nM
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CP0569860
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N-[5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]pyrimidin-2-yl]-2-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrimidin-5-amine
Show/Hide
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C27H34F2N8O3
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1
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| 1 |
IC50 = 14000 nM
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CP0407242
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2-(3-fluorophenyl)-4-[[(3S)-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C19H19FN4OS
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1
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| 1 |
IC50 = 14200 nM
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CP0120528
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2-cyclopropyl-5-methyl-2-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]imidazol-4-amine
Show/Hide
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C21H20N4
|
1
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| 1 |
IC50 = 14400 nM
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CP0076564
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6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-methoxyquinolin-4-amine
Show/Hide
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C19H24N4O3S
|
1
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| 1 |
IC50 = 14500 nM
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CP0508158
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1-((1H-benzo[d]imidazol-2-yl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C26H27F3N6O
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1
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| 1 |
IC50 = 14700 nM
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CP0210817
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(4S)-4-[5-[(2,2-difluoroethylamino)methyl]-2,4-difluorophenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C14H17F4N3S
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1
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| 1 |
IC50 = 14700 nM
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CP0533365
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(E)-N-hydroxy-3-[2-[2-(2-methyl-1H-indol-3-yl)ethyl]-3,4-dihydro-1H-isoquinolin-6-yl]prop-2-enamide
Show/Hide
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C23H25N3O2
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1
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| 1 |
IC50 = 14800 nM
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CP0363811
|
5-[3-amino-4-fluoro-1-(3-pyrimidin-5-ylphenyl)isoindol-1-yl]-1-ethyl-3-methylpyridin-2-one
Show/Hide
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C26H22FN5O
|
1
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| 1 |
IC50 = 15000 nM
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CP0145132
|
AZD7762
Show/Hide
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C17H19FN4O2S
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1
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| 1 |
IC50 = 15000 nM
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CP0543561
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2-imidazo[4,5-b]pyridin-3-yl-1-[(2R)-2-methyl-4-[4-(2-methylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
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C22H21F3N8OS
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1
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| 1 |
IC50 = 15000 nM
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CP0550339
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1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-pyrazolo[3,4-b]pyridin-1-ylethanone
Show/Hide
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C23H23F3N8O2S
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1
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| 1 |
IC50 = 15000 nM
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CP0071793
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(S)-[2,8-bis(trifluoromethyl)-4-quinolinyl]-[(2R)-2-piperidinyl]methanol;hydrochloride
Show/Hide
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C17H16F6N2O
|
1
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| 1 |
IC50 = 15000 nM
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CP0491269
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(E)-3-{3-Fluoro-4-[3-(1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}-N-hydroxyacrylamide
Show/Hide
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C23H24FN3O2
|
1
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| 1 |
IC50 = 15300 nM
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CP0523533
|
ethyl 4-[[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]methyl]piperazine-1-carboxylate
Show/Hide
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C16H19ClN4O3
|
1
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| 1 |
IC50 = 15500 nM
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CP0316875
|
6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)quinolin-4-amine
Show/Hide
|
C18H22N4O2S
|
1
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| 1 |
IC50 = 15500 nM
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CP0532052
|
1-(cyclopropylmethyl)-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C16H15N3
|
1
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| 1 |
IC50 = 15500 nM
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CP0546742
|
N-[4-[[2-[2-(1,1-difluoroethyl)-4,5-difluorophenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]-2-methoxyphenyl]-1-(3-fluoropropyl)azetidin-3-amine
Show/Hide
|
C30H27F5N4O2S
|
1
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| 1 |
IC50 = 15600 nM
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CP0312988
|
3-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-pentan-3-ol
Show/Hide
|
C19H19ClFNO
|
1
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| 1 |
IC50 = 15700 nM
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CP0343337
|
4-[5-(2-chlorophenoxy)indazol-1-yl]-N-methylthiophene-2-carboxamide
Show/Hide
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C19H14ClN3O2S
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1
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| 1 |
IC50 = 15700 nM
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CP0120535
|
N-[5-(5-fluoropyridin-3-yl)-1H-pyrazol-3-yl]-4-piperidin-1-ylbutanamide
Show/Hide
|
C17H22FN5O
|
1
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| 1 |
IC50 = 15800 nM
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CP0237115
|
3-(2-fluoropyridin-3-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
|
C21H18F4N4O3
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1
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| 1 |
IC50 = 15848.93 nM
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CP0416293
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N-[(3S)-5-[2-(hydroxymethyl)pyridin-4-yl]-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C23H20F3N3O4
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1
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| 1 |
IC50 = 15848.93 nM
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CP0433781
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N-[(3S)-5-(2-methoxypyrimidin-5-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxymethyl)pyridine-3-carboxamide
Show/Hide
|
C23H21F3N4O4
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1
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| 1 |
IC50 = 15848.93 nM
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CP0443558
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N-[(3S)-5-[6-(hydroxymethyl)pyridin-3-yl]-3,4-dihydro-2H-chromen-3-yl]-6-[2-(2,2,2-trifluoroethoxy)ethoxy]pyridine-3-carboxamide
Show/Hide
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C25H24F3N3O5
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1
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| 1 |
IC50 = 15848.93 nM
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CP0122486
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6-[[(3R,4R)-3-aminooxan-4-yl]amino]-4-[(5-methoxy-6-propan-2-ylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
|
C19H27N7O3
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1
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| 1 |
IC50 = 15848.93 nM
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CP0367859
|
6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5-fluoro-6-methylpyridin-2-yl)amino]pyridazine-3-carboxamide
Show/Hide
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C17H22FN7O
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1
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| 1 |
IC50 = 15848.93 nM
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CP0407600
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N,N-diethyl-1-[2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetyl]piperidine-3-carboxamide
Show/Hide
|
C29H39F3N4O2
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1
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| 1 |
IC50 = 16000 nM
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CP0256764
|
6-chloro-N-[(3R)-3-[4-[(2-cyanoacetyl)-(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
|
C25H32ClN5O2S
|
1
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| 1 |
IC50 = 16000 nM
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CP0186928
|
3-pyridin-4-yl-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
|
C23H17N5
|
1
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| 1 |
IC50 = 16000 nM
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CP0835810
|
rac-4-Fluoro-1-(4-fluoro-3-(pyrimidin-5-yl)phenyl)-1-(2-(trifluoromethyl)pyridin-4-yl)-1H-isoindol-3-amine
Show/Hide
|
C24H14F5N5
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1
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| 1 |
IC50 = 16000 nM
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CP0846722
|
N-(5-(3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-4-fluoro-2-methylphenyl)acetamide
Show/Hide
|
C19H18FN7O
|
1
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| 1 |
IC50 = 16000 nM
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CP0903919
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N-[5-[[3-cyano-7-(cyclobutylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-4-fluoro-2-methylphenyl]acetamide
Show/Hide
|
C20H20FN7O
|
1
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| 1 |
IC50 = 16000 nM
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CP0490680
|
5-(3-aminopyrazol-1-yl)-2-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]phenol
Show/Hide
|
C23H31N7O
|
1
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| 1 |
IC50 = 16000 nM
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CP0567486
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5-[4-(hydroxymethyl)pyrazol-1-yl]-2-[6-[methyl-(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridazin-3-yl]phenol
Show/Hide
|
C24H32N6O2
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1
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| 1 |
IC50 = 16000 nM
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CP0579065
|
7-methyl-9-[(3S)-1-methylpyrrolidin-3-yl]-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C21H23N7O
|
1
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| 1 |
IC50 = 16000 nM
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CP0961085
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(naphth-2-yl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C24H26ClNO
|
1
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| 1 |
IC50 = 16200 nM
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CP0557192
|
(3R)-3-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C27H28FN3O5
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1
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| 1 |
IC50 = 16500 nM
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CP0213393
|
(4S)-4-[2,4-difluoro-5-[[[3-(trifluoromethyl)oxetan-3-yl]amino]methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C16H18F5N3OS
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1
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| 1 |
IC50 = 16500 nM
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CP0246350
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2-[3-(3-methoxyphenyl)phenyl]-2,5-dimethylimidazol-4-amine
Show/Hide
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C18H19N3O
|
1
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| 1 |
IC50 = 16700 nM
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CP0093117
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[2-[(2S)-3,3-dimethylbutan-2-yl]oxy-5-methylsulfonylphenyl]-[4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C24H29F4N3O4S
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1
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| 1 |
IC50 = 17000 nM
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CP0425343
|
N-(cyclobutylmethyl)-3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]pyrazine-2-carboxamide
Show/Hide
|
C23H24N4O3S
|
1
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| 1 |
IC50 = 17000 nM
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CP0432267
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5-(1H-pyrazol-4-yl)-2-[6-[(2,2,6,6-tetramethylpiperidin-4-yl)methyl]pyridazin-3-yl]phenol
Show/Hide
|
C23H29N5O
|
1
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| 1 |
IC50 = 17000 nM
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CP0578733
|
(1S)-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-[[(2S)-1-methoxy-3-phenylpropan-2-yl]amino]ethanol
Show/Hide
|
C23H22F6N2O2
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1
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| 1 |
IC50 = 17300 nM
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CP0027760
|
3-amino-6-[4-chloro-3-[(2,3-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
Show/Hide
|
C18H14ClF2N5O3S
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1
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| 1 |
IC50 = 17318 nM
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CP0077731
|
(+)-cis-Diltiazem
Show/Hide
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C22H26N2O4S
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1
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| 1 |
IC50 = 17378.01 nM
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CP0259182
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2-(4-methoxy-3,5-dimethylphenyl)-5-methyl-2-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]imidazol-4-amine
Show/Hide
|
C27H26N4O
|
1
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| 1 |
IC50 = 17500 nM
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CP0946460
|
6-(4-(methylsulfinyl)phenyl)-3-(4-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazine
Show/Hide
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C20H17N3O3S2
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1
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| 1 |
IC50 = 17900 nM
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CP0043064
|
4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzamide
Show/Hide
|
C33H39N5O4
|
1
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| 1 |
IC50 = 18000 nM
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CP0082827
|
AT-4140
Show/Hide
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C19H22F2N4O3
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1
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| 1 |
IC50 = 18197.01 nM
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CP0955538
|
N-(3-(methylsulfinyl)phenyl)-3-(4-(methylsulfinyl)phenyl)imidazo[1,2-b]pyridazin-6-amine
Show/Hide
|
C20H18N4O2S2
|
1
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| 1 |
IC50 = 18200 nM
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CP0892683
|
2-amino-1-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)ethanone
Show/Hide
|
C23H23F3N6O3
|
1
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| 1 |
IC50 = 18300 nM
|
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CP0388306
|
N-(2-chlorophenyl)-2-[3-[(E)-[(4-methylphenyl)sulfonylhydrazinylidene]methyl]indol-1-yl]acetamide
Show/Hide
|
C24H21ClN4O3S
|
1
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| 1 |
IC50 = 18660 nM
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CP0107784
|
N-[2-methyl-4-[(3S)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]phenyl]oxane-4-carboxamide
Show/Hide
|
C22H33N3O2
|
1
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| 1 |
IC50 = 18900 nM
|
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CP0141193
|
2-amino-1-[3-(1,3-benzodioxol-5-ylamino)-2-phenyl-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
|
C21H21N5O3
|
1
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| 1 |
IC50 = 19000 nM
|
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CP0184993
|
2-(4-methoxyphenyl)-5-methyl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Show/Hide
|
C22H20N4O
|
1
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| 1 |
IC50 = 19000 nM
|
|
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CP0057281
|
(3S)-3-[2-(difluoromethyl)pyridin-4-yl]-5,7-difluoro-3-(3-pyrimidin-5-ylphenyl)isoindol-1-amine
Show/Hide
|
C24H15F4N5
|
1
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| 1 |
IC50 = 19000 nM
|
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CP0846721
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N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-cyclopropylphenyl]acetamide
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C21H21N7O
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1
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| 1 |
IC50 = 19000 nM
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CP0912079
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N-[2-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-5-methyl-4-pyridyl]acetamide
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C18H18N8O
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1
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| 1 |
IC50 = 19000 nM
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CP0550334
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US9266876, 225
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C24H24N8O2S
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1
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| 1 |
IC50 = 19000 nM
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CP0551814
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1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-pyrazol-1-ylethanone
Show/Hide
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C20H22F3N7O2S
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1
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| 1 |
IC50 = 19000 nM
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CP0533058
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(E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piperidin-1-ylmethyl]phenyl}-N-hydroxyacrylamide
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C29H28FN3O2
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1
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| 1 |
IC50 = 19300 nM
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CP0452092
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(E)-N-Hydroxy-3-(4-{1-[2-(2-methyl-1H-indol-3-yl)ethyl]-pyrrolidin-2-yl}phenyl)acrylamide
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C24H27N3O2
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1
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| 1 |
IC50 = 19400 nM
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CP0404744
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5-chloro-6-oxo-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)-1,6-dihydropyridine-3-carboxamide
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C23H22ClF3N4O2
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1
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| 1 |
IC50 = 19600 nM
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CP0058522
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(4S,4aR,6R,8aS)-8a-(2,4-difluorophenyl)-4-(fluoromethyl)-6-(4-methyl-1,3-oxazol-2-yl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Show/Hide
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C18H18F3N3O2S
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1
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| 1 |
IC50 = 19600 nM
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CP0446908
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8-hydroxy-5-[4-[4-[(2-oxo-3,4-dihydro-1H-quinolin-7-yl)oxy]butyl]-1,4-diazepan-1-yl]-1H-quinolin-2-one
Show/Hide
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C27H32N4O4
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1
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| 1 |
IC50 = 19700 nM
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CP0306005
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(S)-2-phenyl-4-(piperidin-3-ylamino)thieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C19H20N4OS
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1
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| 1 |
IC50 = 19700 nM
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CP0457062
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4-[4-(2,4-dichloro-3-methylphenoxy)piperidin-1-yl]-N-[4-(dimethylamino)phenyl]sulfonylpiperidine-1-carboxamide
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C26H34Cl2N4O4S
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1
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| 1 |
IC50 > 19952.62 nM
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CP0218532
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6-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[(5,6-dimethylpyridin-2-yl)amino]pyridazine-3-carboxamide
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C18H25N7O
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1
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| 1 |
IC50 = 19952.62 nM
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CP0401887
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[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
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C21H21F6N3O4S
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1
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| 1 |
IC50 = 20000 nM
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CP0844912
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rac-4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]-[5-methanesulfonyl-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]-methanone
Show/Hide
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C21H20F7N3O4S
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1
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| 1 |
IC50 = 20000 nM
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CP0048147
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(S)-4-(2-(2-(4-chlorophenyl)-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)-3-(trifluoromethyl)benzoic acid
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C29H25ClF3N3O3
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1
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| 1 |
IC50 > 20000 nM
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CP0048150
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(S)-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)-3-fluorobenzoic acid
Show/Hide
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C28H23ClF3N3O3
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1
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| 1 |
IC50 > 20000 nM
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CP0140156
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(S)-1-(4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)-3-fluorophenoxy)cyclopropanecarboxylic acid
Show/Hide
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C31H27ClF3N3O4
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1
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| 1 |
IC50 > 20000 nM
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CP0225310
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(S)-4-(2-(2-(4-chlorophenyl)-5,6-difluoro-1H-benzo[d]imidazol-1-yl)-2-cyclohexylacetamido)benzoic acid
Show/Hide
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C28H24ClF2N3O3
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1
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| 1 |
IC50 > 20000 nM
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CP0026924
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N-[1-[3-(3-oxo-1,4-benzoxazin-4-yl)propyl]piperidin-4-yl]-2-phenylacetamide
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C24H29N3O3
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1
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| 1 |
IC50 = 20000 nM
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CP0075478
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2-(4-ethylpiperazin-1-yl)-N-(4-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-1-yl)acetamide
Show/Hide
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C33H34N4O4S
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1
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| 1 |
IC50 > 20000 nM
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CP0702676
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(S)-4,11-Dimethoxy-14-methyl-7,8,13b,14-tetrahydroindolo-[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
Show/Hide
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C21H21N3O3
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1
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| 1 |
IC50 = 20000 nM
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CP0413582
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US9266876, 223
Show/Hide
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C26H29N9OS
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1
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| 1 |
IC50 = 20000 nM
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CP0543593
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-4-[4-(2-ethylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C21H25F3N8OS
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1
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| 1 |
IC50 > 20000 nM
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CP0546729
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2-imidazo[4,5-b]pyridin-3-yl-1-[(2R)-4-[4-[2-(2-methoxyethoxy)pyrimidin-5-yl]-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C24H25F3N8O3S
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1
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| 1 |
IC50 > 20000 nM
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CP0546733
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-4-[4-(2-methoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C20H23F3N8O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0546735
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1-[(2R)-4-[4-(2-tert-butylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-(3,5-dimethyl-1,2,4-triazol-1-yl)ethanone
Show/Hide
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C23H29F3N8OS
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1
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| 1 |
IC50 > 20000 nM
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CP0550338
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1-[(2R)-4-[4-[2-[2-(dimethylamino)ethoxy]pyrimidin-5-yl]-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-imidazo[4,5-b]pyridin-3-ylethanone
Show/Hide
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C25H28F3N9O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0550341
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[4-(2-methylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
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C20H23F3N8OS
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1
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| 1 |
IC50 > 20000 nM
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CP0567922
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2-imidazo[4,5-b]pyridin-3-yl-1-[(2R)-4-[4-(2-methoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C22H21F3N8O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0569001
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[4-(2-propylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
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C22H27F3N8OS
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1
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| 1 |
IC50 > 20000 nM
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CP0569010
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[2-(trifluoromethyl)-4-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
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C20H20F6N8OS
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1
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| 1 |
IC50 > 20000 nM
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CP0570252
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-4-[4-(6-methoxypyridin-3-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C21H24F3N7O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0571706
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[4-(2-propan-2-yloxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
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C22H27F3N8O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0573963
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[4-(2-pyrrolidin-1-ylpyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]piperazin-1-yl]ethanone
Show/Hide
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C23H28F3N9OS
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1
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| 1 |
IC50 > 20000 nM
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CP0573965
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-4-[4-(6-ethoxypyridin-3-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C22H26F3N7O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0575647
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2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]ethanone
Show/Hide
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C21H25F3N8O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0578313
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1-[(2R)-4-[4-(2-cyclobutyloxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-(3,5-dimethyl-1,2,4-triazol-1-yl)ethanone
Show/Hide
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C23H27F3N8O2S
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1
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| 1 |
IC50 > 20000 nM
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CP0579887
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9-[(3S)-1-(2-methoxyethyl)pyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
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C23H27N7O2
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1
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| 1 |
IC50 = 20000 nM
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CP0475638
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2-(1-azabicyclo[2.2.2]octan-3-yl)-5-(5-pyridin-3-ylfuran-2-yl)-1,3,4-oxadiazole
Show/Hide
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C18H18N4O2
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1
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| 1 |
IC50 = 20200 nM
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CP0210816
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(4S)-4-[2,4-difluoro-5-[(3,3,3-trifluoropropylamino)methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C15H18F5N3S
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1
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| 1 |
IC50 = 20400 nM
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CP0044035
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1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine
Show/Hide
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C16H19ClN2
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1
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| 1 |
IC50 = 20892.96 nM
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CP0229834
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1-(1-(1H-imidazol-1-yl)-3-methylbutan-2-yl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C26H33F3N6O
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1
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| 1 |
IC50 = 20900 nM
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CP0496060
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(4R,9aR)-4,6-dimethyl-1,2,3,4,9,9a-hexahydro-2,4a,5-triaza-fluorene
Show/Hide
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C12H17N3
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1
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| 1 |
IC50 = 21000 nM
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CP0466588
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2-amino-1-[3-(4-chloro-3-fluoroanilino)-2-(4-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
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C20H18ClF2N5O
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1
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| 1 |
IC50 = 21000 nM
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CP0076328
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2-[3-(3-methoxyphenyl)phenyl]-5-methyl-2-(oxan-4-yl)imidazol-4-amine
Show/Hide
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C22H25N3O2
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1
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| 1 |
IC50 = 21000 nM
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CP0075219
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N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methylphenyl]acetamide
Show/Hide
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C19H19N7O
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1
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| 1 |
IC50 = 21000 nM
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CP0012665
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2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-N-(oxolan-3-yl)-7,8-dihydro-5H-1,6-naphthyridine-6-carboxamide
Show/Hide
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C23H25FN6O3
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1
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| 1 |
IC50 = 21000 nM
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CP0067592
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4-amino-N-[(1S)-1-(4-chlorophenyl)-3-pyrrolidin-1-ylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C25H32ClN7O
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1
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| 1 |
IC50 = 21030 nM
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CP0905313
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3-(3-(methylsulfinyl)phenyl)-6-(4-(methylsulfinyl)phenyl)imidazo[1,2-b]pyridazine
Show/Hide
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C20H17N3O2S2
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1
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| 1 |
IC50 = 21100 nM
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CP0475637
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2-(3-chlorophenyl)-5-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,3,4-oxadiazole
Show/Hide
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C18H15ClN6O2
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1
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| 1 |
IC50 = 21500 nM
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CP0432517
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2-amino-1-[3-(4-fluoroanilino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
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C24H27F2N5O
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1
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| 1 |
IC50 = 21900 nM
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CP0445519
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4-[3-[4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
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C22H25N5O3
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1
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| 1 |
IC50 = 22000 nM
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CP0836441
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(R)-3-Phenyl-3-((6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)propan-1-ol
Show/Hide
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C21H20N4O
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1
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| 1 |
IC50 = 22000 nM
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CP0025032
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2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid
Show/Hide
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C32H39NO4
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1
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| 1 |
IC50 = 23000 nM
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CP0187250
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5-(4-methoxyphenyl)-5-(3-pyrimidin-5-ylphenyl)-3,4-dihydropyrrol-2-amine
Show/Hide
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C21H20N4O
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1
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| 1 |
IC50 = 23000 nM
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CP0513224
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N-ethyl-N-(2-hydroxyethyl)-7-[3-(trifluoromethyl)phenyl]pyrrolo[1,2-b]pyridazine-6-carboxamide
Show/Hide
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C19H18F3N3O2
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1
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| 1 |
IC50 = 23442.29 nM
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CP0073203
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(S)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C26H29F3N4O2
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1
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| 1 |
IC50 = 23900 nM
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CP0239702
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6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-ethylquinolin-4-amine
Show/Hide
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C20H26N4O2S
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1
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| 1 |
IC50 = 23990 nM
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CP0387125
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2-[3-[4-amino-6-[(1-methylpyrazol-4-yl)amino]-1,3,5-triazin-2-yl]-2-(hydroxymethyl)phenyl]-6-cyclopropyl-8-fluoroisoquinolin-1-one
Show/Hide
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C26H23FN8O2
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1
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| 1 |
IC50 = 24000 nM
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CP0074461
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(2S,6R)-2,6-dimethyl-N-[4-[1-(oxan-4-yl)pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl]morpholine-4-carboxamide
Show/Hide
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C24H29N5O3
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1
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| 1 |
IC50 = 24000 nM
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CP0571633
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7-methyl-2-[(7-methylquinolin-6-yl)amino]-9-piperidin-4-ylpurin-8-one
Show/Hide
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C21H23N7O
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1
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| 1 |
IC50 > 24000 nM
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CP0577525
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9-[(3R,4S)-4-fluoro-1-methylpyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
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C21H22FN7O
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1
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| 1 |
IC50 = 24000 nM
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CP0011420
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5-(4-acetyl-1,4-diazepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]pentanamide
Show/Hide
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C22H31N5O3
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1
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| 1 |
IC50 = 24200 nM
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CP0208242
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4-(4-amino-2-cyclopropyl-5-methylimidazol-2-yl)-2-(5-prop-1-ynylpyridin-3-yl)phenol
Show/Hide
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C21H20N4O
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1
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| 1 |
IC50 = 24500 nM
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CP0482451
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3-[2-[2-(hydroxymethyl)piperidine-1-carbonyl]indolizin-3-yl]benzonitrile
Show/Hide
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C22H21N3O2
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1
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| 1 |
IC50 = 24547.09 nM
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CP0183353
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6-[[(3R,4R)-3-aminooxan-4-yl]amino]-8-(1H-indol-7-ylamino)-2H-2,7-naphthyridin-1-one
Show/Hide
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C21H22N6O2
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1
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| 1 |
IC50 = 24900 nM
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CP0039077
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(2R)-2-amino-3-{[(4-methoxyphenyl)diphenylmethyl]sulfanyl}propanoic acid
Show/Hide
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C23H23NO3S
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1
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| 1 |
IC50 > 25000 nM
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CP0086325
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2-amino-5-(3,4-dimethylphenyl)-5,5-diphenylpentanoic acid
Show/Hide
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C25H27NO2
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1
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| 1 |
IC50 > 25000 nM
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CP0156010
|
(2R)-2-amino-3-[(3-ethyl-4-methylphenyl)-diphenylmethyl]sulfanylpropanoic acid
Show/Hide
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C25H27NO2S
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1
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| 1 |
IC50 > 25000 nM
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CP0250629
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(2R)-2-amino-3-[(3,4-dimethylphenyl)-diphenylmethyl]sulfanylpropanoic acid
Show/Hide
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C24H25NO2S
|
1
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| 1 |
IC50 > 25000 nM
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CP0037412
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(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorobenzene)sulfonyl]-2-hydroxy-2-methylpropanamide
Show/Hide
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C18H14F4N2O4S
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1
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| 1 |
IC50 > 25000 nM
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CP0435179
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2-hydroxy-2-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-3-[2-(trifluoromethyl)phenoxy]propanamide
Show/Hide
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C17H15F8NO3S
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1
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| 1 |
IC50 > 25000 nM
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CP0435180
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2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-[3-(pentafluoro-lambda6-sulfanyl)phenoxy]propanamide
Show/Hide
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C17H14F8N2O5S
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1
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| 1 |
IC50 > 25000 nM
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CP0508139
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N-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-[4-(pentafluoro-lambda6-sulfanyl)phenoxy]propanamide
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C18H14F11NO3S
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1
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| 1 |
IC50 > 25000 nM
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CP0037987
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N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Show/Hide
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C22H23N3O4
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1
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| 1 |
IC50 > 25000 nM
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CP0642000
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(S)-2-(6-(4-(hydroxymethyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-phenylethanol
Show/Hide
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C21H20N4O2
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1
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| 1 |
IC50 > 25000 nM
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CP0719016
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(S)-2-(6-(4-(hydroxymethyl)-2-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-phenylethanol
Show/Hide
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C22H22N4O3
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1
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| 1 |
IC50 > 25000 nM
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CP0834035
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(S)-2-((6-(4-(((2-(Dimethylamino)ethyl)amino)methyl)-2-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-phenylethan-1-ol
Show/Hide
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C26H32N6O2
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1
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| 1 |
IC50 > 25000 nM
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CP0910394
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(S)-2-phenyl-2-((6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)ethan-1-ol
Show/Hide
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C20H18N4O
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1
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| 1 |
IC50 > 25000 nM
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CP0954281
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(S)-2-(3-(4-((2-Hydroxy-1-phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl)acetamide
Show/Hide
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C22H21N5O2
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1
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| 1 |
IC50 > 25000 nM
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CP0955541
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(S)-2-(6-(2-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-2-phenylethanol
Show/Hide
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C21H20N4O2
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1
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| 1 |
IC50 > 25000 nM
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CP0957322
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(S)-2-((6-(4-(((2-(Dimethylamino)ethyl)amino)methyl)-3-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-phenylethan-1-ol
Show/Hide
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C25H29FN6O
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1
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| 1 |
IC50 > 25000 nM
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CP0959438
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(S)-2-((6-(2-(Methoxy-d3)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-phenylethan-1-ol
Show/Hide
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C21H20N4O2
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1
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| 1 |
IC50 > 25000 nM
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CP0436277
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N-[(3S)-5-(5-fluoro-6-methoxypyridin-3-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
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C23H19F4N3O4
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1
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| 1 |
IC50 = 25118.86 nM
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CP0452264
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N-[(3S)-5-pyridin-3-yl-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
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C22H18F3N3O3
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1
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| 1 |
IC50 = 25118.86 nM
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CP0010654
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4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-ylamino)-3,5-dimethylbenzonitrile
Show/Hide
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C20H15BrN6O
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1
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| 1 |
IC50 = 25118.86 nM
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CP0476246
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N-[(1R,2S)-1-[3-(dimethylamino)propanoylamino]-2,3-dihydro-1H-inden-2-yl]-5-methyl-1H-indole-2-carboxamide
Show/Hide
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C24H28N4O2
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1
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| 1 |
IC50 = 25118.86 nM
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CP0555289
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6-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]thiazin-3-one
Show/Hide
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C26H26FN5O4S
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1
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| 1 |
IC50 = 25700 nM
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CP0135402
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(R)-1-(2-hydroxy-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C26H29F3N4O2
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1
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| 1 |
IC50 = 25800 nM
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CP0658097
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5-(1H-indol-7-ylamino)-3-((1R,2S)-2-aminocyclohexylamino)-1,2,4-triazine-6-carboxamide
Show/Hide
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C18H22N8O
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1
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| 1 |
IC50 = 25900 nM
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CP0946461
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3-(4-(methylsulfinyl)phenyl)-N-(1-(methylsulfonyl)piperidin-4-yl)imidazo[1,2-b]pyridazin-6-amine
Show/Hide
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C19H23N5O3S2
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1
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| 1 |
IC50 = 25900 nM
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CP0353237
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5-Chloro-1-(4-fluoro-phenyl)-3-propyl-1H-indole
Show/Hide
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C17H15ClFN
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1
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| 1 |
IC50 = 26000 nM
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CP0433107
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1-(1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-(cyclohexylmethylamino)ethanone
Show/Hide
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C24H36N2O
|
1
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| 1 |
IC50 = 26000 nM
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CP0955539
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3-(4-(methylsulfinyl)phenyl)-N-(4-(methylsulfonyl)phenyl)imidazo[1,2-b]pyridazin-6-amine
Show/Hide
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C20H18N4O3S2
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1
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| 1 |
IC50 = 26100 nM
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CP0526305
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2-[[methyl-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]amino]methyl]-3H-quinazolin-4-one
Show/Hide
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C19H17N5O2
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1
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| 1 |
IC50 = 26200 nM
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CP0546807
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N-[3-[2-[4-amino-1-(4-hydroxycyclohexyl)pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C28H25F3N6O2
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1
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| 1 |
IC50 = 26420 nM
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CP0456057
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N-[2-(2-methylimidazol-1-yl)-1-phenylethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
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C31H34F3N5O
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1
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| 1 |
IC50 = 26600 nM
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CP0208245
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2-(4-methoxyphenyl)-5-propan-2-yl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
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C23H23N5O
|
1
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| 1 |
IC50 = 26800 nM
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CP0056899
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(2-Benzhydryloxy-ethyl)-dimethyl-amine
Show/Hide
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C17H21NO
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1
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| 1 |
IC50 = 26915.35 nM
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CP0232176
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4-amino-N-[1-(4-fluorophenyl)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C20H23FN6O
|
1
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| 1 |
IC50 = 26957 nM
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CP0221355
|
5-(4-chlorophenyl)-N-(3-methylphenyl)furan-2-carboxamide
Show/Hide
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C18H14ClNO2
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1
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| 1 |
IC50 = 27000 nM
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CP0061167
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2-[(4-benzylpiperazin-1-yl)methyl]-5-phenyl-1,3,4-oxadiazole
Show/Hide
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C20H22N4O
|
1
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| 1 |
IC50 = 27300 nM
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CP0543544
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N-[4-[[2-[2-(1,1-difluoroethyl)-4-fluorophenyl]-6H-thieno[2,3-e]indazol-3-yl]oxy]-2-fluorophenyl]-1-(3-fluoropropyl)azetidin-3-amine
Show/Hide
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C29H25F5N4OS
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1
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| 1 |
IC50 = 27500 nM
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CP0522085
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(E)-N-Hydroxy-3-{4-[3-(2-methyl-1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}acrylamide
Show/Hide
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C24H27N3O2
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1
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| 1 |
IC50 = 27600 nM
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CP0496554
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N-methyl-N-(3-oxo-3-pyrrolidin-1-ylpropyl)-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
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C27H35F3N4O2
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1
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| 1 |
IC50 = 28000 nM
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CP0486889
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[2-[(2R)-3,3-dimethylbutan-2-yl]oxy-5-methylsulfonylphenyl]-[4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
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C24H29F4N3O4S
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1
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| 1 |
IC50 = 28000 nM
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CP0419808
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4-[[(3S)-piperidin-3-yl]amino]-2-thiophen-3-ylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C17H18N4OS2
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1
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| 1 |
IC50 = 28000 nM
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CP0566822
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(3R)-3-[[4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C26H24F3N3O5
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1
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| 1 |
IC50 = 28200 nM
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CP0030612
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4-[4-(4-fluorophenyl)-2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-N-(4-piperazin-1-ylphenyl)pyrimidin-2-amine
Show/Hide
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C29H32FN7S
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1
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| 1 |
IC50 = 28200 nM
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CP0483342
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2-[[4-[4-(4-fluorophenyl)-2-piperidin-4-yl-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]-1-pyridin-4-ylethanol
Show/Hide
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C25H25FN6OS
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1
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| 1 |
IC50 = 28200 nM
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CP0532348
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(E)-N-Hydroxy-3-{4-[3-(2-phenyl-1H-indol-3-yl)piperidin-1-ylmethyl]phenyl}acrylamide
Show/Hide
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C29H29N3O2
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1
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| 1 |
IC50 = 28400 nM
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CP0210814
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1-[[5-[(4S)-2-amino-4-methyl-5,6-dihydro-1,3-thiazin-4-yl]-2,4-difluorophenyl]methylamino]cyclopropane-1-carbonitrile
Show/Hide
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C16H18F2N4S
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1
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| 1 |
IC50 = 28400 nM
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CP0239141
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2-cyclohexyl-5-methyl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Show/Hide
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C21H24N4
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1
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| 1 |
IC50 = 28800 nM
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CP0946923
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4-((3-(4-(Methylsulfinyl)phenyl)imidazo[1,2-b]pyridazin-6-yl)amino)tetrahydro-2Hthiopyran-1,1-dioxide
Show/Hide
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C18H20N4O3S2
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1
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| 1 |
IC50 = 28800 nM
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CP0470133
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(E)-N-Hydroxy-3-{4-[3-(1H-indol-3-yl)piperidin-1-ylmethyl]-phenyl}acrylamide
Show/Hide
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C23H25N3O2
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1
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| 1 |
IC50 = 29300 nM
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CP0067496
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4-amino-N-[(1S)-1-(4-chlorophenyl)-3-piperidin-1-ylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C26H34ClN7O
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1
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| 1 |
IC50 = 29367 nM
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CP0059838
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(4R,9aR)-6-Cyclopropylmethoxymethyl-4-methyl-1,2,3,4,9,9a-hexahydro-2,4a,5-triaza-fluorene
Show/Hide
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C16H23N3O
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1
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| 1 |
IC50 > 30000 nM
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CP0051021
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5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide
Show/Hide
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C19H16ClNO4
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1
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| 1 |
IC50 > 30000 nM
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CP0210100
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5-(4-chlorophenyl)-N-cyano-N'-(3-methylphenyl)furan-2-carboxamide
Show/Hide
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C19H14ClN3O
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1
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| 1 |
IC50 > 30000 nM
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CP0215373
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5-(4-chlorophenyl)-N-[(5-methyl)pyridin-3-yl]furan-2-carboxamide
Show/Hide
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C17H13ClN2O2
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1
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| 1 |
IC50 > 30000 nM
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CP0261810
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5-[(4-trifluoromethoxy)phenyl]-N-(3-methylphenyl)furan-2-carboxamide
Show/Hide
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C19H14F3NO3
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1
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| 1 |
IC50 > 30000 nM
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CP0158421
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5-(3-(pyridin-2-ylmethyl)pyrrolidin-3-yl)-1H-indole
Show/Hide
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C18H19N3
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1
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| 1 |
IC50 > 30000 nM
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CP0376561
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(E)-3-{4-[3-(2-tert-Butyl-1H-indol-3-yl)piperidin-1-ylmethyl]-3-fluorophenyl}-N-hydroxyacrylamide
Show/Hide
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C27H32FN3O2
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1
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| 1 |
IC50 = 30000 nM
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CP0503451
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2-amino-1-[3-(4-fluoroanilino)-2-(3-fluorophenyl)-6,8-dihydro-5H-imidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
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C20H19F2N5O
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1
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| 1 |
IC50 > 30000 nM
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CP0434131
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2-amino-1-[2-(4-fluorophenyl)-8,8-dimethyl-3-(4-methylanilino)-5,6-dihydroimidazo[1,2-a]pyrazin-7-yl]-2-methylpropan-1-one
Show/Hide
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C25H30FN5O
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1
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| 1 |
IC50 > 30000 nM
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CP0459283
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2-amino-1-[3-(3,4-difluoroanilino)-2-(4-fluorophenyl)-8,8-dimethyl-5,6-dihydroimidazo[1,2-a]pyrazin-7-yl]ethanone
Show/Hide
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C22H22F3N5O
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1
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| 1 |
IC50 > 30000 nM
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CP0514863
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3-(3-chloro-4-fluoroanilino)-2-(4-fluorophenyl)-8,8-dimethyl-5,7-dihydroimidazo[1,2-a]pyrazin-6-one
Show/Hide
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C20H17ClF2N4O
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1
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| 1 |
IC50 > 30000 nM
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CP0165878
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(2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylphenyl)sulfonylpiperidine-2-carboxamide
Show/Hide
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C23H25N3O4S2
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1
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| 1 |
IC50 > 30000 nM
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CP0434783
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2-[[4-(1,3-benzothiazol-2-ylmethyl)piperazin-1-yl]methyl]-5-phenyl-1,3,4-oxadiazole
Show/Hide
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C21H21N5OS
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1
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| 1 |
IC50 = 30000 nM
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CP0482543
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4-[2-[(4-chloro-3-phenyl-1H-pyrazol-5-yl)methylamino]pyridin-4-yl]-3-methylbenzonitrile
Show/Hide
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C23H18ClN5
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1
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| 1 |
IC50 = 30000 nM
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CP0482544
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4-[2-[(4-chloro-3-pyridin-2-yl-1H-pyrazol-5-yl)methylamino]pyridin-4-yl]-3-methylbenzonitrile
Show/Hide
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C22H17ClN6
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1
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| 1 |
IC50 > 30000 nM
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CP0055294
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2-[4-(2-hydroxyethyl)piperazin-1-yl]-N-[4-(2-morpholin-4-yl-4-oxochromen-8-yl)dibenzothiophen-1-yl]acetamide
Show/Hide
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C33H34N4O5S
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1
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| 1 |
IC50 > 30000 nM
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CP0053415
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4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
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C33H38N4O5
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1
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| 1 |
IC50 > 30000 nM
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CP0075166
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4-[6-ethyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
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C34H40N4O5
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1
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| 1 |
IC50 > 30000 nM
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CP0085221
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4-[5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]sulfanylbenzoic acid
Show/Hide
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C32H36N4O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0068661
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2-[4-[[3-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]propan-2-ol
Show/Hide
|
C21H25ClN4O
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1
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| 1 |
IC50 > 30000 nM
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CP0114551
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2-[4-[[3-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexyl]propan-2-ol
Show/Hide
|
C22H25F3N4O
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1
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| 1 |
IC50 > 30000 nM
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CP0114708
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4-[[3-[3-(trifluoromethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexan-1-ol
Show/Hide
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C19H19F3N4O2
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1
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| 1 |
IC50 > 30000 nM
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CP0177776
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4-[[3-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-5-yl]amino]cyclohexan-1-ol
Show/Hide
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C19H19F3N4O
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1
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| 1 |
IC50 > 30000 nM
|
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CP0118574
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7-[[(1R,2S)-2-aminocyclohexyl]amino]-5-(1H-indol-7-ylamino)-3H-pyrido[4,3-d]pyrimidin-4-one
Show/Hide
|
C21H23N7O
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1
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| 1 |
IC50 > 30000 nM
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|
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CP0776455
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4-(1H-indol-7-ylamino)-2-((1R,2S)-2-aminocyclohexylamino)pyrimidine-5-carboxamide
Show/Hide
|
C19H23N7O
|
1
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| 1 |
IC50 > 30000 nM
|
|
|
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CP0796446
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2-(1H-indol-7-ylamino)-6-((1R,2S)-2-aminocyclohexylamino)nicotinamide
Show/Hide
|
C20H24N6O
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0194663
|
7-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-1H-pyrido[3,4-b][1,4]oxazin-2-one
Show/Hide
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C26H26FN5O5
|
1
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| 1 |
IC50 = 30000 nM
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CP0367923
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2-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-8H-pyrimido[5,4-b][1,4]oxazin-7-one
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C25H25FN6O5
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1
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| 1 |
IC50 = 30000 nM
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CP0511084
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2-(4-chlorophenyl)-5-[4-[(3S,4S)-3,4-dihydroxypyrrolidin-1-yl]-3-methoxyphenyl]-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
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C22H21ClN4O4
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1
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| 1 |
IC50 > 30000 nM
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CP0272596
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N-[1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]-N-methyl-3-oxo-4H-pyrido[3,2-b][1,4]oxazine-6-carboxamide
Show/Hide
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C27H28FN5O5
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1
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| 1 |
IC50 > 30000 nM
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CP0453242
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N-[1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]-3-oxo-4H-pyrido[3,2-b][1,4]oxazine-6-carboxamide
Show/Hide
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C26H26FN5O5
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1
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| 1 |
IC50 > 30000 nM
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CP0366449
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6-[[[1-[(1S)-2-[3-fluoro-6-(2-hydroxyethoxy)-1,5-naphthyridin-4-yl]-1-hydroxyethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
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C27H30FN5O6
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1
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| 1 |
IC50 > 30000 nM
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CP0528791
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(1R,2S)-2-[[7-fluoro-8-[2-[4-[(3-oxo-4H-pyrido[3,2-b][1,4]oxazin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]ethyl]-1,5-naphthyridin-2-yl]oxymethyl]cyclopropane-1-carboxylic acid
Show/Hide
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C30H32FN5O6
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1
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| 1 |
IC50 > 30000 nM
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CP0567159
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6-[[[1-[2-[6-(2-aminoethoxy)-3-fluoro-1,5-naphthyridin-4-yl]ethyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
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C27H31FN6O4
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1
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| 1 |
IC50 > 30000 nM
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CP0567336
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(1S,2S)-2-[[7-fluoro-8-[2-[4-[(3-oxo-4H-pyrido[3,2-b][1,4]oxazin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]ethyl]-1,5-naphthyridin-2-yl]oxymethyl]cyclopropane-1-carboxylic acid
Show/Hide
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C30H32FN5O6
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1
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| 1 |
IC50 > 30000 nM
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CP0468176
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MLS000328049
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C18H21N3O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0500194
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US8975247, EBP143
Show/Hide
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C15H13ClN2O
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1
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| 1 |
IC50 > 30000 nM
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CP0576018
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US8975247, EBP108
Show/Hide
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C16H13F3N2O2S
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1
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| 1 |
IC50 > 30000 nM
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CP0519453
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4-[[(3S)-piperidin-3-yl]amino]-2-thiophen-2-ylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
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C17H18N4OS2
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1
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| 1 |
IC50 > 30000 nM
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CP0429796
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(8S)-N-methyl-N-[[6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]methyl]-5,6,7,8-tetrahydroquinolin-8-amine
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C20H28N6
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1
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| 1 |
IC50 > 30000 nM
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CP0082507
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4-[[4-amino-6-[3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2-yl)-2-(hydroxymethyl)phenyl]-1,3,5-triazin-2-yl]amino]-1-propan-2-ylpyrrole-2-carbonitrile
Show/Hide
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C30H27FN8O2
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1
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| 1 |
IC50 = 30000 nM
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CP0435320
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4-[[4-amino-6-[3-(6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2-yl)-2-(hydroxymethyl)phenyl]-1,3,5-triazin-2-yl]amino]-1-cyclopropylpyrrole-2-carbonitrile
Show/Hide
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C30H25FN8O2
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1
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| 1 |
IC50 = 30000 nM
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CP0421331
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2-[6-(3,3-difluoropiperidin-4-yl)oxypyridazin-3-yl]-5-pyrazol-1-ylphenol
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C18H17F2N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0421332
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5-pyrazol-1-yl-2-[6-[2,2,6,6-tetramethyl-1-(2,2,2-trifluoroethyl)piperidin-4-yl]oxypyridazin-3-yl]phenol
Show/Hide
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C24H28F3N5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0421436
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6-naphthalen-1-yl-N-(2,2,6,6-tetramethylpiperidin-4-yl)pyridazin-3-amine
Show/Hide
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C23H28N4
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1
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| 1 |
IC50 > 30000 nM
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CP0076563
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2-[6-tert-butylsulfonyl-4-[(4,5-dimethyl-1H-pyrazol-3-yl)amino]quinolin-7-yl]oxyethanol
Show/Hide
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C20H26N4O4S
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1
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| 1 |
IC50 > 30000 nM
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CP0202738
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6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-(trifluoromethoxy)quinolin-4-amine
Show/Hide
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C19H21F3N4O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0243151
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6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-(2-methoxyethoxy)quinolin-4-amine
Show/Hide
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C21H28N4O4S
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1
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| 1 |
IC50 = 30000 nM
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CP0249226
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6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-ethoxyquinolin-4-amine
Show/Hide
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C20H26N4O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0115609
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N-hydroxy-2-[2-[6-(6-methoxypyridin-3-yl)-4-methylquinazolin-8-yl]oxyethyl-methylamino]pyrimidine-5-carboxamide
Show/Hide
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C23H23N7O4
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1
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| 1 |
IC50 > 30000 nM
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CP0136714
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7-[6-(5-fluoro-6-methoxypyridin-3-yl)-4-methylquinazolin-8-yl]oxy-N-hydroxyheptanamide
Show/Hide
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C22H25FN4O4
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1
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| 1 |
IC50 > 30000 nM
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CP0412290
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-bromo-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Show/Hide
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C21H26BrFN3O9P
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1
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| 1 |
IC50 > 30000 nM
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CP0412295
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propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-bromo-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate
Show/Hide
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C21H26BrFN3O9P
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1
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| 1 |
IC50 > 30000 nM
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CP0074483
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4-ethyl-N-[4-[1-(oxan-4-yl)pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl]piperazine-1-carboxamide
Show/Hide
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C24H30N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0270792
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(2S,6R)-N-[4-[1-(4-hydroxy-4-methylcyclohexyl)pyrrolo[2,3-c]pyridin-3-yl]pyridin-2-yl]-2,6-dimethylmorpholine-4-carboxamide
Show/Hide
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C26H33N5O3
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1
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| 1 |
IC50 > 30000 nM
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CP0390388
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1-(oxan-4-yl)-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C17H17N3O
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1
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| 1 |
IC50 > 30000 nM
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CP0396849
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1-[(3-methyloxetan-3-yl)methyl]-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C17H17N3O
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1
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| 1 |
IC50 > 30000 nM
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CP0414623
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1-(2-methylpropyl)-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C16H17N3
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1
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| 1 |
IC50 = 30000 nM
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CP0493840
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1-phenyl-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C18H13N3
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1
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| 1 |
IC50 > 30000 nM
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CP0532054
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1-(2-methoxyethyl)-3-pyridin-4-ylpyrrolo[2,3-c]pyridine
Show/Hide
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C15H15N3O
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1
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| 1 |
IC50 > 30000 nM
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CP0029277
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4-[[6-fluoro-4-hydroxy-8-(methylamino)-2-oxo-1H-quinoline-3-carbonyl]amino]benzoic acid
Show/Hide
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C18H14FN3O5
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1
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| 1 |
IC50 > 30000 nM
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CP0029700
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3-[[cyclohexyl(2-hydroxyethyl)amino]methyl]-4-[[6-fluoro-8-(methylamino)-2-oxo-1H-quinoline-3-carbonyl]amino]benzoic acid;hydrochloride
Show/Hide
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C27H32ClFN4O5
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1
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| 1 |
IC50 > 30000 nM
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CP0033595
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N-[4-(dimethylsulfamoylcarbamoyl)phenyl]-6-fluoro-4-hydroxy-8-(methylamino)-2-oxo-1H-quinoline-3-carboxamide
Show/Hide
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C20H20FN5O6S
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1
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| 1 |
IC50 > 30000 nM
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CP0562640
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1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-3-methyl-6-[5-(trifluoromethyl)-2- thienyl]imidazo[4,5-b]pyridin-2-one
Show/Hide
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C17H15F3N4O2S
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1
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| 1 |
IC50 > 30000 nM
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CP0004656
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3,5-diamino-N-(diaminomethylidene)-6-(2-methoxypyrimidin-5-yl)pyrazine-2-carboxamide
Show/Hide
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C11H13N9O2
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1
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| 1 |
IC50 > 30000 nM
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CP0083553
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3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride
Show/Hide
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C6H8ClN7O
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1
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| 1 |
IC50 > 30000 nM
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CP0189395
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3-amino-5-(azepan-1-yl)-N-(diaminomethylidene)-6-(2-methoxypyrimidin-5-yl)pyrazine-2-carboxamide
Show/Hide
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C17H23N9O2
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1
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| 1 |
IC50 > 30000 nM
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CP0142470
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US10266537, Compound 93
Show/Hide
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C29H27F3N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0492803
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N-[3-[2-[4-amino-1-[(2S)-3-hydroxy-2-methylpropyl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C26H23F3N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0492804
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N-[3-[2-[4-amino-1-[(2S)-3-hydroxy-2-methylpropyl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-4-methyl-3-(trifluoromethyl)benzamide
Show/Hide
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C27H25F3N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0511774
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N-[3-[2-[4-amino-1-[(2R)-3-hydroxy-2-methylpropyl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Show/Hide
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C26H23F3N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0568850
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N-[3-[2-[4-amino-1-[(2S)-3-hydroxy-2-methylpropyl]pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-4-chloro-3-(trifluoromethyl)benzamide
Show/Hide
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C26H22ClF3N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0573294
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N-[3-[2-[4-amino-1-(4-hydroxycyclohexyl)pyrazolo[3,4-d]pyrimidin-3-yl]ethynyl]-4-methylphenyl]-4-chloro-3-(trifluoromethyl)benzamide
Show/Hide
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C28H24ClF3N6O2
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1
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| 1 |
IC50 > 30000 nM
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CP0549751
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2-methyl-4-(4-methylpiperazin-1-yl)-6-[[(2S)-2-(3-methylpyridin-2-yl)pyrrolidin-1-yl]methyl]pyrimidine
Show/Hide
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C21H30N6
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1
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| 1 |
IC50 > 30000 nM
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CP0551575
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4-[4-[5-(hydroxymethyl)-1,2-oxazol-3-yl]phenyl]-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
Show/Hide
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C28H18F3NO4
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1
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| 1 |
IC50 > 30000 nM
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CP0131014
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4-[5-(2-chloroanilino)-6-fluoroindazol-1-yl]-N-methylthiophene-2-carboxamide
Show/Hide
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C19H14ClFN4OS
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1
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| 1 |
IC50 > 30000 nM
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CP0131029
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4-[4-[(2-chlorophenyl)carbamoylamino]pyrazol-1-yl]-N-(oxetan-3-yl)thiophene-2-carboxamide
Show/Hide
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C18H16ClN5O3S
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1
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| 1 |
IC50 > 30000 nM
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CP0176840
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4-[5-(2-chloro-6-fluoroanilino)-6-methylpyrazolo[3,4-b]pyridin-1-yl]-N-methylthiophene-2-carboxamide
Show/Hide
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C19H15ClFN5OS
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1
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| 1 |
IC50 > 30000 nM
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CP0547938
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4-chloro-N-[(1R)-1-[(1S,5R)-3-(6-chlorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
Show/Hide
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C23H23Cl2N3O
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1
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| 1 |
IC50 > 30000 nM
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CP0557813
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4-chloro-N-[(1R)-1-[(1R,5S)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]ethyl]benzamide
Show/Hide
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C22H20ClF2N3O
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1
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| 1 |
IC50 > 30000 nM
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CP0274501
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3,8-dihydroxy-7-(piperidin-1-ylmethyl)-[1]benzofuro[3,2-c]chromen-6-one
Show/Hide
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C21H19NO5
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1
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| 1 |
IC50 > 30000 nM
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CP0579976
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9-[(3S)-1-(2-hydroxyethyl)pyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
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C22H25N7O2
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1
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| 1 |
IC50 = 30000 nM
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CP0576005
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(1R)-1-[2,8-bis(trifluoromethyl)quinolin-4-yl]-2-(heptylamino)ethanol
Show/Hide
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C20H24F6N2O
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1
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| 1 |
IC50 > 30000 nM
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CP0012669
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2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-6-(2-methylsulfonylethyl)-7,8-dihydro-1,6-naphthyridin-5-one
Show/Hide
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C21H22FN5O4S
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1
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| 1 |
IC50 = 30000 nM
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CP0013148
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1-[2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-5,7-dihydropyrrolo[3,4-b]pyridin-6-yl]ethanone
Show/Hide
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C19H18FN5O2
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1
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| 1 |
IC50 = 30000 nM
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CP0013267
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4-[2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridine-6-carbonyl]-1-methylpyrrolidin-2-one
Show/Hide
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C24H25FN6O3
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1
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| 1 |
IC50 = 30000 nM
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CP0014557
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[2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-(oxolan-2-yl)methanone
Show/Hide
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C23H24FN5O3
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1
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| 1 |
IC50 > 30000 nM
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CP0014603
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[2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-(oxolan-3-yl)methanone
Show/Hide
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C23H24FN5O3
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1
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| 1 |
IC50 = 30000 nM
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CP0014635
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2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-N-(1-methyl-5-oxopyrrolidin-3-yl)-7,8-dihydro-5H-1,6-naphthyridine-6-carboxamide
Show/Hide
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C24H26FN7O3
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1
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| 1 |
IC50 > 30000 nM
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CP0015089
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1-[2-[[3-(4-fluorophenyl)-5-methyltriazol-4-yl]methoxy]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethanone
Show/Hide
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C20H20FN5O2
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1
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| 1 |
IC50 > 30000 nM
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CP0150720
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2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Show/Hide
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C21H25ClN2O3
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1
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| 1 |
IC50 = 30199.52 nM
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CP0448237
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(3R)-3-[[4-[(5,7-dichloro-2,3-dihydro-1,4-benzodioxin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C27H26Cl2FN3O5
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1
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| 1 |
IC50 = 30400 nM
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CP0566820
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[6-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-3-oxo-4H-pyrido[3,2-b][1,4]oxazin-7-yl] benzoate
Show/Hide
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C33H30FN5O7
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1
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| 1 |
IC50 = 30500 nM
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CP0546528
|
(3R)-3-[[4-[(1,4-dimethyl-2,3-dihydropyrido[2,3-b]pyrazin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C28H33FN6O3
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1
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| 1 |
IC50 = 30600 nM
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CP0398984
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1-(3-(pyrrolidine-1-carbonyl)piperidin-1-yl)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
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C29H37F3N4O2
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1
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| 1 |
IC50 = 31000 nM
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CP0383079
|
ethyl 4-[[5-(5-chloro-2-fluorophenyl)-1,2,4-oxadiazol-3-yl]methyl]piperazine-1-carboxylate
Show/Hide
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C16H18ClFN4O3
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1
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| 1 |
IC50 = 31000 nM
|
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CP0053278
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(5-bromo-1-methylpyrrolo[2,3-c]pyridin-2-yl)-[6-[(dimethylamino)methyl]-3,4-dihydro-1H-isoquinolin-2-yl]methanone
Show/Hide
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C21H23BrN4O
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1
|
| 1 |
IC50 = 31200 nM
|
|
|
|
CP0372478
|
N-[(5-chloro-6-oxo-1H-pyridin-3-yl)-(4-fluorophenyl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H29ClF4N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0407601
|
1-(2-(pyrrolidine-1-carbonyl)morpholino)-2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ethanone
Show/Hide
|
C28H35F3N4O3
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0454256
|
N-[(4-fluorophenyl)-(6-oxo-1H-pyridin-3-yl)methyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H30F4N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0456058
|
3-((4-fluorophenyl)(2-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)acetamido)methyl)pyridine 1-oxide
Show/Hide
|
C31H30F4N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0472052
|
N-[1-(6-oxo-1H-pyridin-3-yl)pentyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C29H35F3N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0534722
|
N-[1-(6-oxo-1H-pyridin-3-yl)ethyl]-2-[1-[[1-[4-(trifluoromethyl)phenyl]pyrrol-3-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C26H29F3N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0127555
|
3-phenyl-3-(3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)ureido)propanoic acid
Show/Hide
|
C27H29F3N4O3
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0208350
|
1-(1-(1H-imidazol-1-yl)propan-2-yl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C24H29F3N6O
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0208352
|
1-(1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C28H30F3N7O
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0254230
|
1-(2-(1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C29H31F3N6O
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0357226
|
1-(2-(2-methyl-1H-imidazol-1-yl)-1-phenylethyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C30H33F3N6O
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0398527
|
1-((1-hydroxycyclohexyl)methyl)-3-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C25H33F3N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0404743
|
(R)-3-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C22H27F3N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0422023
|
4-fluoro-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-ylcarbamoyl)benzenesulfonamide
Show/Hide
|
C24H24F4N4O3S
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0422024
|
3-(1,1-Dioxo-1lambda6-thiomorpholin-4-yl)-azetidine-1-carboxylic acid{1-[1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-ylmethyl]-piperidin-4-yl}-amide
Show/Hide
|
C25H32F3N5O3S
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0431390
|
(S)-3-hydroxy-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C22H27F3N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0452878
|
3-acetamido-N-(1-((1-(4-(trifluoromethyl)phenyl)-1H-pyrrol-3-yl)methyl)piperidin-4-yl)pyrrolidine-1-carboxamide
Show/Hide
|
C24H30F3N5O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0534807
|
1-(3-Hydroxy-adamantan-1-yl)-3-{1-[1-(4-trifluoromethyl-phenyl)-1H-pyrrol-3-ylmethyl]-piperidin-4-yl}-urea
Show/Hide
|
C28H35F3N4O2
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0448239
|
(3R)-3-[[4-[(5,6-dichloro-2,3-dihydro-1,4-benzodioxin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H26Cl2FN3O5
|
1
|
| 1 |
IC50 = 31600 nM
|
|
|
|
CP0042443
|
(S)-1-(5-phenyl-3-(piperidin-3-ylcarbamoyl)thiophen-2-yl)urea
Show/Hide
|
C17H20N4O2S
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0120980
|
4-[2-hydroxyethyl-[(3S)-piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C21H24N4O2S
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0419809
|
2-phenyl-7-[[(3S)-piperidin-3-yl]amino]thieno[2,3-c]pyridine-4-carboxamide
Show/Hide
|
C19H20N4OS
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0463930
|
4-[[(2R,3S)-2-methylpiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C20H22N4OS
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0519454
|
2-(3-fluorophenyl)-7-[[(3S)-piperidin-3-yl]amino]thieno[2,3-c]pyridine-4-carboxamide
Show/Hide
|
C19H19FN4OS
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0534744
|
4-[[(2R,3S)-2-(2-hydroxyethyl)piperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C21H24N4O2S
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0558622
|
4-[[(3S,4S)-4-hydroxypiperidin-3-yl]amino]-2-phenylthieno[3,2-c]pyridine-7-carboxamide
Show/Hide
|
C19H20N4O2S
|
1
|
| 1 |
IC50 > 31600 nM
|
|
|
|
CP0436278
|
N-[(3S)-5-(5-methylpyrazin-2-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C22H19F3N4O3
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0523038
|
N-[(3S)-5-(5-methoxypyrazin-2-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide
Show/Hide
|
C22H19F3N4O4
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0410428
|
N-ethyl-N-(2-hydroxyethyl)-7-(3-methylphenyl)pyrrolo[1,2-b]pyridazine-6-carboxamide
Show/Hide
|
C19H21N3O2
|
1
|
| 1 |
IC50 > 31622.78 nM
|
|
|
|
CP0079365
|
N-[(1S,2S)-1-[2-(dimethylamino)ethylcarbamoyl]-2,3-dihydro-1H-inden-2-yl]-1H-indole-2-carboxamide
Show/Hide
|
C23H26N4O2
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0429018
|
3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
IC50 > 32000 nM
|
|
|
|
CP0450472
|
6-methoxy-3-[[4-(methylsulfinylmethyl)naphthalene-1-carbonyl]amino]-N-(oxan-4-ylmethyl)pyridine-2-carboxamide
Show/Hide
|
C26H29N3O5S
|
1
|
| 1 |
IC50 > 32000 nM
|
|
|
|
CP0967782
|
(E)-N-(Chroman-7-methyl)-N-methyl-3-(4-biphenyl)prop-2-en-1-amine Hydrochloride
Show/Hide
|
C26H28ClNO
|
1
|
| 1 |
IC50 = 32100 nM
|
|
|
|
CP0899462
|
N,3-bis(4-(methylsulfinyl)phenyl)imidazo[1,2-b]pyridazin-6-amine
Show/Hide
|
C20H18N4O2S2
|
1
|
| 1 |
IC50 = 32300 nM
|
|
|
|
CP0383239
|
ethyl 4-[[5-(5-chloro-2-fluorophenyl)-1,3,4-oxadiazol-2-yl]methyl]piperazine-1-carboxylate
Show/Hide
|
C16H18ClFN4O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0428853
|
2-[[methyl-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]amino]methyl]-3H-quinazolin-4-one
Show/Hide
|
C19H17N5O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0489095
|
ethyl 4-[[5-(3-chlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]piperazine-1-carboxylate
Show/Hide
|
C16H19ClN4O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0139044
|
5-N-[(3R)-3-[4-[methoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-4,6-dimethyl-2-N-propan-2-ylpyridine-2,5-dicarboxamide
Show/Hide
|
C28H42N6O4S
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0076329
|
2-phenyl-5-propan-2-yl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
|
C22H21N5
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0103310
|
2,5-dimethyl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Show/Hide
|
C16H16N4
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0120529
|
(2R)-2-(4-methoxy-3,5-dimethylphenyl)-5-methyl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0149822
|
(2R)-2-benzyl-5-methyl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
|
C21H19N5
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0184992
|
1-[4-[4-amino-2-[3-(3-methoxyphenyl)phenyl]-5-methylimidazol-2-yl]piperidin-1-yl]ethanone
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0186617
|
2-(4-fluorophenyl)-5-methyl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Show/Hide
|
C21H17FN4
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0187560
|
(2S)-2-(4-methoxy-3,5-dimethylphenyl)-5-methyl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0210692
|
2-(4-methoxy-3-methylphenyl)-5-methyl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
|
C22H21N5O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0300566
|
2-methyl-5-phenyl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Show/Hide
|
C21H18N4
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0335078
|
2-(4-methoxyphenyl)-5-methyl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
Show/Hide
|
C21H19N5O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0487940
|
2-methyl-5-propan-2-yl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Show/Hide
|
C18H20N4
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0724458
|
2-(4-Methoxy-3,5-dimethylphenyl)-5-methyl-2-(3-(pyrimidin-5-yl)phenyl)-2H-imidazol-4-amine
Show/Hide
|
C23H23N5O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0192105
|
5-[3-amino-4-fluoro-1-(3-pyrimidin-5-ylphenyl)isoindol-1-yl]-1,3-dimethylpyridin-2-one
Show/Hide
|
C25H20FN5O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0010753
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]-4-(hydroxymethyl)piperidin-4-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C21H32Cl2N4O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0296630
|
N-(1-adamantyl)-2-[4-[2-(tert-butylcarbamoylamino)ethyl]piperazin-1-yl]acetamide
Show/Hide
|
C23H41N5O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0333311
|
N-[[1-[2-(tert-butylcarbamoylamino)ethyl]-4-hydroxypiperidin-4-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C20H30Cl2N4O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0449008
|
N-[[4-[2-(tert-butylcarbamoylamino)ethyl]morpholin-2-yl]methyl]-3,5-dichlorobenzamide
Show/Hide
|
C19H28Cl2N4O3
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0105035
|
2-methyl-2-(3-pyrimidin-5-ylphenyl)-5,6-dihydro-1,3-thiazin-4-amine
Show/Hide
|
C15H16N4S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0338940
|
1-[5-amino-2-[3-(3-methoxyphenyl)phenyl]-2-methyl-4H-imidazol-3-yl]ethanone
Show/Hide
|
C19H21N3O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0846704
|
N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-4-fluoro-2-methylphenyl)acetamide
Show/Hide
|
C19H18FN7O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0853304
|
N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylphenyl)acetamide
Show/Hide
|
C19H19N7O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0861956
|
N-[5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-isopropyl-phenyl]acetamide
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0883719
|
N-[5-[[3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-cyclopropyl-4-fluorophenyl]acetamide
Show/Hide
|
C21H20FN7O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0884122
|
N-[2-Chloro-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide
Show/Hide
|
C18H16ClN7O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0908801
|
N-(5-(3-Cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-methylpyridin-3-yl)acetamide
Show/Hide
|
C18H18N8O
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0921304
|
N-(5-(3-cyano-7-(oxetan-3-ylamino)pyrazolo[1,5-a]pyrimidin-5-ylamino)-2-cyclopropylphenyl)acetamide
Show/Hide
|
C21H21N7O2
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0334283
|
8-[1-[2-(4-acetylpiperazin-1-yl)ethoxy]dibenzothiophen-4-yl]-2-morpholin-4-ylchromen-4-one
Show/Hide
|
C33H33N3O5S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0401455
|
2-N-methyl-4-N-(2,2,2-trifluoroethyl)-6-[4-(trifluoromethyl)phenyl]thieno[3,2-d]pyrimidine-2,4-diamine
Show/Hide
|
C16H12F6N4S
|
1
|
| 1 |
IC50 > 33000 nM
|
|
|
|
CP0308349
|
(4S)-4-[5-[(cyclopropylmethylamino)methyl]-2,4-difluorophenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
|
C16H21F2N3S
|
1
|
| 1 |
IC50 = 33000 nM
|
|
|
|
CP0377615
|
N-ethyl-N-(2-hydroxyethyl)-3-(3-methoxyphenyl)indolizine-2-carboxamide
Show/Hide
|
C20H22N2O3
|
1
|
| 1 |
IC50 > 33113.11 nM
|
|
|
|
CP0486606
|
[2-(hydroxymethyl)piperidin-1-yl]-[3-(3-methoxyphenyl)indolizin-2-yl]methanone
Show/Hide
|
C22H24N2O3
|
1
|
| 1 |
IC50 > 33113.11 nM
|
|
|
|
CP0493886
|
N-ethyl-N-(2-hydroxyethyl)-3-(6-methoxypyridin-2-yl)indolizine-2-carboxamide
Show/Hide
|
C19H21N3O3
|
1
|
| 1 |
IC50 > 33113.11 nM
|
|
|
|
CP0065817
|
N-[2-acetamido-1-(4-chlorophenyl)ethyl]-4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C22H26ClN7O2
|
1
|
| 1 |
IC50 > 33300 nM
|
|
|
|
CP0065819
|
4-amino-N-[(1S)-1-(4-chlorophenyl)-3-(dimethylamino)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C23H30ClN7O
|
1
|
| 1 |
IC50 > 33300 nM
|
|
|
|
CP0067594
|
4-amino-N-(1-pyridin-3-ylethyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C19H23N7O
|
1
|
| 1 |
IC50 > 33300 nM
|
|
|
|
CP0085487
|
4-amino-N-[1-(4-chlorophenyl)-3-sulfamoylpropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C21H26ClN7O3S
|
1
|
| 1 |
IC50 > 33300 nM
|
|
|
|
CP0085488
|
4-amino-N-[1-(4-chlorophenyl)-4-piperidin-1-ylbutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C27H36ClN7O
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1
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| 1 |
IC50 > 33300 nM
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CP0115541
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4-amino-N-(1-pyridin-2-ylethyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C19H23N7O
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1
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| 1 |
IC50 > 33300 nM
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CP0142487
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4-amino-N-[1-(4-chlorophenyl)-2-(methanesulfonamido)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C21H26ClN7O3S
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1
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| 1 |
IC50 > 33300 nM
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CP0156043
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4-amino-N-(1-phenylethyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
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C20H24N6O
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1
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| 1 |
IC50 > 33300 nM
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CP0214202
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4-amino-N-[1-(4-chlorophenyl)-3-(dimethylamino)-3-oxopropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C23H28ClN7O2
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1
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| 1 |
IC50 > 33300 nM
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CP0232178
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4-amino-N-[1-(4-chlorophenyl)-2-sulfamoylethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C20H24ClN7O3S
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1
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| 1 |
IC50 > 33300 nM
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CP0250592
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4-amino-N-[1-(4-methylsulfonylphenyl)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
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C21H26N6O3S
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1
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| 1 |
IC50 > 33300 nM
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CP0556138
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(3R)-5-fluoro-3-hydroxy-3-[[4-([1,3]oxathiolo[5,4-c]pyridin-6-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
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C25H25FN4O4S
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1
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| 1 |
IC50 = 33600 nM
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CP0478172
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ALBACONAZOLE
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C20H16ClF2N5O2
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1
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| 1 |
IC50 = 34860 nM
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CP0475527
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4-(4-fluorophenyl)-5-[2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine
Show/Hide
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C23H22FN7S
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1
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| 1 |
IC50 = 35500 nM
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CP0070912
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3,5-dimethyl-N-[2-methyl-4-[(3S)-3-[(2S)-2-methylpyrrolidin-1-yl]pyrrolidin-1-yl]phenyl]-1,2-oxazole-4-carboxamide
Show/Hide
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C22H30N4O2
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1
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| 1 |
IC50 = 37000 nM
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CP0483341
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N-[4-(4-fluorophenyl)-5-[2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-yl]acetamide
Show/Hide
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C25H24FN7OS
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1
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| 1 |
IC50 = 38000 nM
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CP0571631
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7-methyl-2-[(7-methylquinolin-6-yl)amino]-9-[(3S)-1-(oxetan-3-yl)pyrrolidin-3-yl]purin-8-one
Show/Hide
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C23H25N7O2
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1
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| 1 |
IC50 > 38000 nM
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CP0436958
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(4R,9aR)-6-chloro-4-methyl-1,2,3,4,9,9a-hexahydro-2,4a,5-triaza-fluorene
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C11H14ClN3
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1
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| 1 |
IC50 = 40000 nM
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CP0425945
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[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]methanone
Show/Hide
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C20H20F6N4O4S
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1
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| 1 |
IC50 > 40000 nM
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CP0438725
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[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone
Show/Hide
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C20H20F6N4O4S
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1
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| 1 |
IC50 > 40000 nM
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CP0504367
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[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]methanone
Show/Hide
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C20H20F6N4O4S
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1
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| 1 |
IC50 > 40000 nM
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CP0073217
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6-chloro-N-[(3R)-3-[4-[2-methoxyethoxycarbamoyl(thiophen-3-ylmethyl)amino]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
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C26H38ClN5O4S
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1
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| 1 |
IC50 > 40000 nM
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CP0403864
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4-[4-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]benzoic acid
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C33H37N3O5
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1
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| 1 |
IC50 > 40000 nM
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CP0041632
|
ITRAZOLE
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C35H38Cl2N8O4
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1
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| 1 |
IC50 > 40000 nM
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CP0083484
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(2R,3S)-2,3-bis(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
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C16H14F3N5O
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1
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| 1 |
IC50 > 40000 nM
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CP0469357
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(2R,3R)-2-(2,4-difluorophenyl)-3-(2-pyrimidin-5-yl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridin-5-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol;sulfuric acid;hydrate
Show/Hide
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C22H21F2N7OS
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1
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| 1 |
IC50 > 40000 nM
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CP0549701
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5-[7-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-6,8-dihydro-5H-[1,2,4]triazolo[1,5-a]pyrazin-2-yl]pyridine-2-carbonitrile
Show/Hide
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C23H21F2N9O
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1
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| 1 |
IC50 > 40000 nM
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CP0380504
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N-[1-(4-bromo-2-fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide
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C23H24BrFN4O3
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1
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| 1 |
IC50 > 40000 nM
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CP0380505
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N'-hydroxy-N-[1-(naphthalen-2-ylamino)isoquinolin-7-yl]octanediamide
Show/Hide
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C27H28N4O3
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1
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| 1 |
IC50 > 40000 nM
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CP0428724
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N'-hydroxy-N-[1-(4-methylanilino)isoquinolin-7-yl]octanediamide
Show/Hide
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C24H28N4O3
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1
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| 1 |
IC50 > 40000 nM
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CP0431475
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N-[1-(3-chloro-2-fluoroanilino)isoquinolin-7-yl]-N'-hydroxyoctanediamide
Show/Hide
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C23H24ClFN4O3
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1
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| 1 |
IC50 > 40000 nM
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CP0184289
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1-(3-methyl-4-morpholin-4-ylphenyl)-3-[4-(3-methyl-2H-pyrazolo[3,4-b]pyridin-4-yl)phenyl]urea
Show/Hide
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C25H26N6O2
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1
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| 1 |
IC50 > 40000 nM
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CP0681670
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(E,E)-N-(Chroman-7-methyl)-N-methyl-5-(4-biphenyl)pent-2,4-dien-1-amine Hydrochloride
Show/Hide
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C28H30ClNO
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1
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| 1 |
IC50 > 40000 nM
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CP0198404
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4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-thiophen-3-ylpropyl]cyclohexane-1-carboxamide
Show/Hide
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C27H39F2N5OS
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1
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| 1 |
IC50 > 40000 nM
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CP0024094
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(4'R,6'S,7'S)-17'-fluoro-13'-[(5R)-5-(methoxymethyl)-2-oxo-1,3-thiazolidin-3-yl]-4',6'-dimethylspiro[1,3-diazinane-5,8'-5,15-dioxa-2,14-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(17),10,12(16),13-tetraene]-2,4,6-trione
Show/Hide
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C23H24FN5O7S
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1
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| 1 |
IC50 > 40000 nM
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CP0029328
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(4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(5S)-5-methyl-2-oxo-1,3-thiazolidin-3-yl]spiro[1,3-diazinane-5,8'-5,15-dioxa-2,14-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(17),10,12(16),13-tetraene]-2,4,6-trione
Show/Hide
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C22H22FN5O6S
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1
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| 1 |
IC50 > 40000 nM
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CP0030583
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(4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(5R)-5-methyl-2-oxo-1,3-thiazolidin-3-yl]spiro[1,3-diazinane-5,8'-5,15-dioxa-2,14-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(17),10,12(16),13-tetraene]-2,4,6-trione
Show/Hide
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C22H22FN5O6S
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1
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| 1 |
IC50 > 40000 nM
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CP0034062
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(4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-(5-oxo-4-oxa-6-azaspiro[2.4]heptan-6-yl)spiro[1,3-diazinane-5,8'-5,15-dioxa-2,14-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(17),10,12(16),13-tetraene]-2,4,6-trione
Show/Hide
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C23H22FN5O7
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1
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| 1 |
IC50 > 40000 nM
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CP0528951
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(4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-(2-oxo-1,3-thiazolidin-3-yl)spiro[1,3-diazinane-5,8'-5,15-dioxa-2,14-diazatetracyclo[8.7.0.02,7.012,16]heptadeca-1(17),10,12(16),13-tetraene]-2,4,6-trione
Show/Hide
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C21H20FN5O6S
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1
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| 1 |
IC50 > 40000 nM
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CP0498403
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3-[4-[4-[4-[3-(1-benzylpiperidin-4-yl)propanoyl]phenyl]piperazin-1-yl]butyl]-1H-indole-5-carbonitrile
Show/Hide
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C38H45N5O
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1
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| 1 |
IC50 > 40000 nM
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CP0552016
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9-[(3R,4R)-4-fluoro-1-methylpyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
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C21H22FN7O
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1
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| 1 |
IC50 > 40000 nM
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CP0578239
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7-methyl-2-[(7-methylcinnolin-6-yl)amino]-9-(1-methylpiperidin-4-yl)purin-8-one
Show/Hide
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C21H24N8O
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1
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| 1 |
IC50 > 40000 nM
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CP0579416
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9-[(3R,4S)-4-fluoropyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
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C20H20FN7O
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1
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| 1 |
IC50 > 40000 nM
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CP0545402
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2-[2-(1,1-difluoroethyl)-4,5-difluorophenyl]-3-[3-fluoro-4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6H-thieno[2,3-e]indazole
Show/Hide
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C29H23F6N3O2S
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1
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| 1 |
IC50 > 40000 nM
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CP0551988
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2-[2-(1,1-difluoroethyl)-4-fluorophenyl]-3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxy-3-methoxyphenoxy]-6H-thieno[2,3-e]indazole
Show/Hide
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C30H27F4N3O3S
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1
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| 1 |
IC50 > 40000 nM
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CP0568223
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2-[4-fluoro-2-(2-fluoropropan-2-yl)phenyl]-3-[3-fluoro-4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-6H-thieno[2,3-e]indazole
Show/Hide
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C30H27F4N3O2S
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1
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| 1 |
IC50 > 40000 nM
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CP0569178
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2-[4-fluoro-2-(2-fluoropropan-2-yl)phenyl]-3-[4-[1-(3-fluoropropyl)azetidin-3-yl]oxy-3-methoxyphenoxy]-6H-thieno[2,3-e]indazole
Show/Hide
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C31H30F3N3O3S
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1
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| 1 |
IC50 > 40000 nM
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CP0571814
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3-[3-fluoro-4-[1-(3-fluoropropyl)azetidin-3-yl]oxyphenoxy]-2-[4-fluoro-2-(2,2,2-trifluoroethyl)phenyl]-6H-thieno[2,3-e]indazole
Show/Hide
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C29H23F6N3O2S
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1
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| 1 |
IC50 > 40000 nM
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CP0388305
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N-(2,4-difluorophenyl)-2-[3-[(E)-[(4-methylphenyl)sulfonylhydrazinylidene]methyl]indol-1-yl]acetamide
Show/Hide
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C24H20F2N4O3S
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1
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| 1 |
IC50 = 42970 nM
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CP0523029
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2-[3-[(E)-[(4-methylphenyl)sulfonylhydrazinylidene]methyl]indol-1-yl]-N-phenylacetamide
Show/Hide
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C24H22N4O3S
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1
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| 1 |
IC50 = 43620 nM
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CP0482064
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4-[3-[4-(2-oxo-3H-imidazo[4,5-c]pyridin-1-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
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C22H25N5O3
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1
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| 1 |
IC50 = 46000 nM
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CP0085504
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1-(1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-[(1-hydroxycyclohexyl)methylamino]ethanone
Show/Hide
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C24H36N2O2
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1
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| 1 |
IC50 = 46100 nM
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CP0207107
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(4S)-4-[5-[(cyclopropylamino)methyl]-2,4-difluorophenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Show/Hide
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C15H19F2N3S
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1
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| 1 |
IC50 = 49200 nM
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CP0420948
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1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydro-1,5-naphthyridin-2-one
Show/Hide
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C23H27N5O2
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1
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| 1 |
IC50 > 50000 nM
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CP0425953
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1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydro-1,6-naphthyridin-2-one
Show/Hide
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C23H27N5O2
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1
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| 1 |
IC50 > 50000 nM
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CP0455529
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4-[3-[4-(2-oxo-1H-imidazo[4,5-c]pyridin-3-yl)piperidin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
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C22H25N5O3
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1
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| 1 |
IC50 > 50000 nM
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CP0459323
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1-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-3,4-dihydro-1,7-naphthyridin-2-one
Show/Hide
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C23H27N5O2
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1
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| 1 |
IC50 > 50000 nM
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CP0283663
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4-[[[[1-[(2R)-4-[(6-chloro-2,4-dimethylpyridine-3-carbonyl)amino]butan-2-yl]piperidin-4-yl]-(thiophen-3-ylmethyl)carbamoyl]amino]methyl]benzoic acid
Show/Hide
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C31H38ClN5O4S
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1
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| 1 |
IC50 > 50000 nM
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CP0406690
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1-(1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-[(1-hydroxycycloheptyl)methylamino]ethanone
Show/Hide
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C25H38N2O2
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1
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| 1 |
IC50 = 50100 nM
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CP0521153
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N-[4-(4-fluorophenyl)-5-[2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-1-methylpiperidine-4-carboxamide
Show/Hide
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C30H33FN8OS
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1
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| 1 |
IC50 = 50100 nM
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CP0046619
|
Adalat
Show/Hide
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C17H18N2O6
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1
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| 1 |
IC50 = 50118.72 nM
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CP0052206
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1-Cyclopropyl-6-fluoro-5-methyl-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4,4a,8a-tetrahydro-quinoline-3-carboxylic acid (Grepafloxacin)
Show/Hide
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C19H22FN3O3
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1
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| 1 |
IC50 = 50118.72 nM
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CP0270696
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3-(2-methylpyridin-3-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
Show/Hide
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C22H21F3N4O3
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1
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| 1 |
IC50 = 50118.72 nM
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CP0006743
|
4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
Show/Hide
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C16H19NO3S
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1
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| 1 |
IC50 > 50118.72 nM
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CP0005166
|
BMS-354825
Show/Hide
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C22H26ClN7O2S
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1
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| 1 |
IC50 = 50118.72 nM
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CP0011140
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N-[(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]-1-benzofuran-2-carboxamide
Show/Hide
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C22H23N3O2
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1
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| 1 |
IC50 = 54000 nM
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CP0550847
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1-(1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-[2-(2,6-dichlorophenyl)ethylamino]ethanone
Show/Hide
|
C25H30Cl2N2O
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1
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| 1 |
IC50 = 54700 nM
|
|
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CP0067589
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4-amino-N-[1-(4-chlorophenyl)-4-hydroxybutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C22H27ClN6O2
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1
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| 1 |
IC50 = 57793 nM
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CP0133264
|
A-56268
Show/Hide
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C38H69NO13
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1
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| 1 |
IC50 = 58884.37 nM
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CP0123212
|
(3R)-3-[[4-[(5-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C27H27ClFN3O5
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1
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| 1 |
IC50 > 60000 nM
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CP0194662
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6-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-7-methyl-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
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C27H28FN5O5
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1
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| 1 |
IC50 > 60000 nM
|
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CP0194683
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(3R)-3-[[4-[(8-chloro-2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C26H26ClFN4O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0194684
|
(3R)-5-fluoro-3-hydroxy-3-[[4-(1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-6-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C26H29FN6O3
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0257060
|
(3R)-5-fluoro-3-hydroxy-3-[[4-[(3-methyl-2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H29FN4O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0257224
|
(3R)-3-[[4-(1,3-benzodioxol-5-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C26H26FN3O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0257248
|
(3R)-5-fluoro-3-[[4-[(6-fluoro-2,3-dihydro-1,4-benzodioxin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H27F2N3O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0286018
|
(3R)-5-fluoro-3-hydroxy-3-[[4-[(2-methyl-2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H29FN4O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0286019
|
(3R)-3-[[4-[(1,1-dioxo-2,3-dihydro-[1,4]oxathiino[2,3-c]pyridin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
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C26H27FN4O6S
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0286020
|
(3R)-5-fluoro-3-hydroxy-3-[[4-[(4-methyl-2,3-dihydropyrido[3,2-b][1,4]oxazin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H30FN5O4
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0347527
|
(3R)-3-[[4-(6,7-dihydro-[1,4]dioxino[2,3-c]pyridazin-3-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C25H26FN5O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0362596
|
7-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-8-carbonitrile
Show/Hide
|
C27H26FN5O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0367924
|
(3R)-3-[[4-[(5,8-dichloro-2,3-dihydro-1,4-benzodioxin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H26Cl2FN3O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0463213
|
(3R)-3-[[4-[(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C27H27ClFN3O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0511464
|
(3R)-3-[[4-(2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C26H27FN4O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0511465
|
(3R)-3-[[4-(3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazin-6-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C26H28FN5O4
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0560825
|
7-ethyl-6-[[[1-[[(3R)-5-fluoro-3-hydroxy-11-oxo-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-3-yl]methyl]-2-oxabicyclo[2.2.2]octan-4-yl]amino]methyl]-4H-pyrido[3,2-b][1,4]oxazin-3-one
Show/Hide
|
C28H30FN5O5
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0560826
|
(3R)-3-[[4-(2,3-dihydro-[1,4]oxathiino[3,2-c]pyridin-7-ylmethylamino)-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C26H27FN4O4S
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0566821
|
(3R)-3-[[4-[(4,4-dioxo-2,3-dihydro-[1,4]oxathiino[3,2-c]pyridin-7-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-5-fluoro-3-hydroxy-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
Show/Hide
|
C26H27FN4O6S
|
1
|
| 1 |
IC50 > 60000 nM
|
|
|
|
CP0115543
|
4-amino-N-[1-(4-chlorophenyl)-4-morpholin-4-ylbutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C26H34ClN7O2
|
1
|
| 1 |
IC50 = 74807 nM
|
|
|
|
CP0322115
|
4-(5-Chloro-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-piperidin-4-yl}-indol-1-yl)-benzoic acid
Show/Hide
|
C25H27ClN4O3
|
1
|
| 1 |
IC50 = 75000 nM
|
|
|
|
CP0571634
|
9-[(3R,4R)-4-fluoropyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
IC50 = 75000 nM
|
|
|
|
CP0840926
|
3-(4-methylpiperazin-1-yl)-N-(quinolin-7-ylmethyl)-7-(trifluoromethyl)quinolin-5-amine
Show/Hide
|
C25H24F3N5
|
1
|
| 1 |
IC50 = 75800 nM
|
|
|
|
CP0448337
|
1-[(1R)-1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl]-2-[(1-hydroxycyclohexyl)methylamino]ethanone
Show/Hide
|
C24H36N2O2
|
1
|
| 1 |
IC50 = 76000 nM
|
|
|
|
CP0386934
|
1-(1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-[(1-hydroxycyclopentyl)methylamino]ethanone
Show/Hide
|
C23H34N2O2
|
1
|
| 1 |
IC50 = 78600 nM
|
|
|
|
CP0002124
|
4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1S,5S)-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-phenyl-propyl}-amide
Show/Hide
|
C29H41F2N5O
|
1
|
| 1 |
IC50 = 79432.82 nM
|
|
|
|
CP0002231
|
2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phenyl}-5-methyl-7-propyl-3H,4H-imidazo[1,5-a][1,2,4]triazin-4-one
Show/Hide
|
C23H32N6O4S
|
1
|
| 1 |
IC50 = 79432.82 nM
|
|
|
|
CP0550048
|
2-(4-chlorophenyl)-5-[4-[(3R)-3-hydroxypyrrolidin-1-yl]-3-methoxyphenyl]-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C22H21ClN4O3
|
1
|
| 1 |
IC50 > 80000 nM
|
|
|
|
CP0085486
|
4-amino-N-[1-(4-chlorophenyl)-3-(methanesulfonamido)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C22H28ClN7O3S
|
1
|
| 1 |
IC50 = 80124 nM
|
|
|
|
CP0732200
|
1-ethyl-3-(3-((3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinolin-5-ylamino)methyl)phenyl)urea
Show/Hide
|
C25H29F3N6O
|
1
|
| 1 |
IC50 = 81700 nM
|
|
|
|
CP0572655
|
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[1-[2-[(1-methylpiperidin-4-yl)amino]ethyl]pyrazol-4-yl]pyrimidin-2-amine;trihydrochloride
Show/Hide
|
C24H34Cl3F2N7O3
|
1
|
| 1 |
IC50 = 83000 nM
|
|
|
|
CP0778289
|
(S)-1-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)-3-(pyrrolidin-2-yl)prop-2-en-1-one
Show/Hide
|
C28H29F3N6O3
|
1
|
| 1 |
IC50 = 86200 nM
|
|
|
|
CP0573945
|
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[1-(2-piperazin-1-ylethyl)pyrazol-4-yl]pyrimidin-2-amine;trihydrochloride
Show/Hide
|
C22H30Cl3F2N7O3
|
1
|
| 1 |
IC50 = 89000 nM
|
|
|
|
CP0049757
|
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
Show/Hide
|
C21H29N3O
|
1
|
| 1 |
IC50 = 91201.08 nM
|
|
|
|
CP0840924
|
4-(dimethylamino)-1-(4-(5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)but-2-en-1-one
Show/Hide
|
C27H29F3N6O3
|
1
|
| 1 |
IC50 = 92100 nM
|
|
|
|
CP0840925
|
1-(3-((3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinolin-5-ylamino)methyl)phenyl)ethanone
Show/Hide
|
C24H25F3N4O
|
1
|
| 1 |
IC50 = 93600 nM
|
|
|
|
CP0052645
|
1-[(1S)-1-cyclohexyl-3,4-dihydro-1H-isoquinolin-2-yl]-2-[(1-hydroxycyclohexyl)methylamino]ethanone
Show/Hide
|
C24H36N2O2
|
1
|
| 1 |
IC50 = 98000 nM
|
|
|
|
CP0308131
|
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine
Show/Hide
|
C16H15N3
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0067497
|
4-amino-N-[1-(4-chlorophenyl)-4-pyrrolidin-1-ylbutyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C26H34ClN7O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0067595
|
4-amino-N-[1-(4-chlorophenyl)-4-(dimethylamino)butyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C24H32ClN7O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0115544
|
4-amino-N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C23H30ClN7O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0115545
|
4-amino-N-[1-(3,4-dimethoxyphenyl)ethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C22H28N6O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0156046
|
4-amino-N-[2-amino-1-(4-chlorophenyl)-2-oxoethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C20H22ClN7O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0232175
|
4-amino-N-[1-(4-chlorophenyl)-2-hydroxyethyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C20H23ClN6O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0669680
|
(S)-4-Amino-N-[1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7Hpyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C21H25ClN6O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0696504
|
rac-4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
Show/Hide
|
C21H25ClN6O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0843165
|
1-(4-(5-([2H]-3-nitrobenzylamino)-7-(trifluoromethyl)quinolin-3-yl)piperazin-1-yl)ethanone
Show/Hide
|
C23H22F3N5O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0426050
|
1-[6,6-bis(4-fluorophenyl)hexyl]-4-[[4-methoxy-3,5-bis[(2-methylpropan-2-yl)oxy]phenyl]methyl]piperazine-2,5-dione
Show/Hide
|
C38H48F2N2O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0013112
|
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate
Show/Hide
|
C27H37N3O7S
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0055239
|
N-[2-[2-aminoethyl(methyl)amino]-5-[[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino]phenyl]acetamide
Show/Hide
|
C21H25N9O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0176871
|
4-[5-(2-chloroanilino)pyrazolo[3,4-b]pyridin-1-yl]-N-methylthiophene-2-carboxamide
Show/Hide
|
C18H14ClN5OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0473312
|
7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one
Show/Hide
|
C18H20N8O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0070817
|
N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine
Show/Hide
|
C20H22F3N5O
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0069510
|
CAS_442-52-4
Show/Hide
|
C19H20ClN3
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0442922
|
US8975247, EBP163
Show/Hide
|
C20H22ClN3O
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0556045
|
US8975247, EBP315
Show/Hide
|
C21H24ClN3
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0131026
|
4-[5-(2-chloroanilino)-6-fluoroindazol-1-yl]-N-[(3S)-1-(trideuteriomethyl)pyrrolidin-3-yl]thiophene-2-carboxamide
Show/Hide
|
C23H21ClFN5OS
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0356524
|
4-[5-(2-chloroanilino)indazol-1-yl]-N-[(3S)-1-(trideuteriomethyl)pyrrolidin-3-yl]thiophene-2-carboxamide
Show/Hide
|
C23H22ClN5OS
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0568052
|
5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-[methyl-(1-methylpiperidin-4-yl)amino]piperidin-1-yl]phenyl]pyrimidin-2-amine;tetrahydrochloride
Show/Hide
|
C33H48Cl4F2N6O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
|
CP0579302
|
Azeliragon
Show/Hide
|
C32H38ClN3O2
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0046202
|
4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-5'-yloxy)-hexyl]phenoxy}butyric Acid
Show/Hide
|
C37H40O6
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0068015
|
4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobiphenyl-3-yloxy)hexyl)-2-(2-carboxyethyl)phenoxy)butanoic acid
Show/Hide
|
C38H39FO8
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0093685
|
4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-yloxy)hexyl)phenoxy)butanoic acid
Show/Hide
|
C36H39NO6
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0093691
|
4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphenoxy)hexyl]-2-(2-carboxyethyl)phenoxy}butyric Acid
Show/Hide
|
C36H38O8S
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0018791
|
US10112937, Example 228
Show/Hide
|
C17H12F5N7O
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0030383
|
US10112937, Example 220
Show/Hide
|
C18H13F5N6O
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0123962
|
3-amino-5-(azepan-1-yl)-6-(1-benzofuran-2-yl)-N-(diaminomethylidene)pyrazine-2-carboxamide
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 < 3000 nM
|
|
|
|
CP0543518
|
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]pyrimidin-2-amine
Show/Hide
|
C25H29F2N5O4
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0567849
|
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
Show/Hide
|
C30H38F2N6O4
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0570287
|
5-[(2,6-difluoro-3,5-dimethoxyphenyl)methoxy]-N-[3-ethoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
Show/Hide
|
C31H40F2N6O4
|
1
|
| 1 |
IC50 > 3000 nM
|
|
|
|
CP0567919
|
1-[(2R)-4-[4-(2-ethoxypyrimidin-5-yl)-2-(trifluoromethyl)-1,3-thiazol-5-yl]-2-methylpiperazin-1-yl]-2-[3-(trifluoromethyl)-1,2,4-triazol-1-yl]ethanone
Show/Hide
|
C20H20F6N8O2S
|
1
|
| 1 |
IC50 > 6000 nM
|
|
|
|
CP0847421
|
N-(2-{7-[2-(4-chlorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-cyano-N-methylbenzenesulfonamide
Show/Hide
|
C24H29ClN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847426
|
N-[2-(7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)ethyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C21H26FN3O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847427
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)propane-2-sulfonamide
Show/Hide
|
C21H32N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847428
|
N-[2-(7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)ethyl]-4-cyanobenzenesulfonamide
Show/Hide
|
C23H28N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847429
|
4-cyano-N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
|
C23H25N5O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847430
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-methoxybenzenesulfonamide
Show/Hide
|
C25H32N4O5S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847431
|
4-cyano-N-(2-{7-[3-(3,4-difluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C24H28F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847432
|
4-cyano-N-(2-{7-[(5-fluoro-1H-indol-3-yl)methyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C24H26FN5O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847433
|
N-(3-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-4-fluorobenzenesulfonamide
Show/Hide
|
C24H29FN4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847434
|
N-(3-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
|
C24H29FN4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0847435
|
N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-2,3-dihydro-1-benzofuran-5-sulfonamide
Show/Hide
|
C25H29FN4O5S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0851330
|
4-cyano-N-(3-{7-[2-(2,6-difluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
|
C24H28F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0851347
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1,1,1-trifluoromethanesulfonamide
Show/Hide
|
C19H25F3N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0858389
|
N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-2-fluorobenzenesulfonamide
Show/Hide
|
C23H27FN4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0858390
|
4-cyano-N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}-N-methylbenzenesulfonamide
Show/Hide
|
C24H27N5O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0858391
|
N-(2-(7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo[3.3.1]nonan-3-yl)ethyl)-4-fluorobenzenesulfonamide
Show/Hide
|
C22H25FN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0858392
|
N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diaza-bicyclo [3.3.1]non-3-yl}ethyl)-N-methyl-2,3-dihydro-1-benzofuran-5-sulfonamide
Show/Hide
|
C26H31FN4O5S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0862740
|
N-(tert-butyl)-3-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propane-1-sulfonamide
Show/Hide
|
C23H36N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0862741
|
N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}-1-phenylmethanesulfonamide
Show/Hide
|
C23H28N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0862742
|
N-{3-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]propyl}-3,5-dimethylisoxazole-4-sulfonamide
Show/Hide
|
C22H29N5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864368
|
N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1-phenylmethanesulfonamide
Show/Hide
|
C24H30N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864369
|
N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1-[4-(trifluoromethyl)phenyl]methane-sulfonamide
Show/Hide
|
C25H29F3N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864370
|
5-chloro-N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diaza-bicyclo[3.3.1]non-3-yl}ethyl)-1,3-dimethyl-1H-pyrazole-4-sulfonamide
Show/Hide
|
C22H29ClN6O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864371
|
N-(3-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-1-phenylmethanesulfonamide
Show/Hide
|
C25H32N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864372
|
3-cyano-N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C24H27N5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864373
|
N-(3-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)-4-fluorobenzenesulfonamide
Show/Hide
|
C24H28F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864374
|
4-cyano-N-[2-(7-{2-[4-(trifluoromethyl)phenyl]ethyl}-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)ethyl]benzenesulfonamide
Show/Hide
|
C24H27F3N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864375
|
4-cyano-N-(2-{7-[2-(2,6-difluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C23H26F2N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864376
|
4-cyano-N-(2-{7-[2-(2-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C23H27FN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864377
|
N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]-non-3-yl}ethyl)-N-methyl-2,3-dihydro-1-benzofuran-5-sulfonamide
Show/Hide
|
C26H32N4O5S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0864378
|
4-cyano-N-(3-{7-[2-(4-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
|
C24H29FN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919412
|
N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)methanesulfonamide
Show/Hide
|
C18H26N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919413
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)butane-1-sulfonamide
Show/Hide
|
C22H34N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919414
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-2,3-dihydro-1-benzofuran-5-sulfonamide
Show/Hide
|
C26H32N4O5S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919415
|
4-cyano-N-(2-{7-[3-(2,5-difluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C24H28F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919416
|
4-cyano-N-[2-(7-{2-[(4-fluorobenzyl)oxy]ethyl}-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)ethyl]benzenesulfonamide
Show/Hide
|
C24H29FN4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919417
|
4-cyano-N-(2-{7-[2-(3,4-difluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C23H26F2N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919418
|
4-cyano-N-(2-{7-[(3,5-dimethylisoxazol-4-yl)methyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C21H27N5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919419
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-5-methylisoxazole-4-sulfonamide
Show/Hide
|
C22H29N5O5S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919420
|
N-(3-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
|
C24H30N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919421
|
4-cyano-N-(2-{7-[2-(2,6-difluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C23H26F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919422
|
4-cyano-N-(3-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
|
C25H28FN5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919423
|
N-(3-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)-2,4-difluorobenzene-sulfonamide
Show/Hide
|
C24H27F3N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919424
|
N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-4-fluorobenzenesulfonamide
Show/Hide
|
C23H26F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919425
|
N-[2-(7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)ethyl]-4-cyano-N-methylbenzenesulfonamide
Show/Hide
|
C23H28N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919426
|
4-cyano-N-{3-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]propyl}benzenesulfonamide
Show/Hide
|
C24H27N5O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919427
|
4-cyano-N-{3-[7-(4-fluorobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]propyl}benzenesulfonamide
Show/Hide
|
C23H27FN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0919428
|
4-cyano-N-(3-{7-[2-(2,6-difluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
|
C24H28F2N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921072
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1-phenylmethanesulfonamide
Show/Hide
|
C25H32N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921074
|
4-cyano-N-{2-[7-(4-fluorobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}-N-methylbenzenesulfonamide
Show/Hide
|
C23H27FN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921075
|
N-(4-cyanobenzyl)-2-{7-[(3,5-dimethylisoxazol-4-yl)methyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethanesulfonamide
Show/Hide
|
C22H29N5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921076
|
N-{2-[7-(1,2-benzisoxazol-3-ylmethyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}-4-cyanobenzenesulfonamide
Show/Hide
|
C23H25N5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921077
|
N-[3-(7-benzyl-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl)propyl]-4-cyanobenzenesulfonamide
Show/Hide
|
C23H28N4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921078
|
4-cyano-N-(2-{7-[3-(4-fluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
|
C25H31FN4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0921079
|
4-cyano-N-(2-{7-[3-(2,4-difluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C24H28F2N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0933012
|
N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C24H30N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0933014
|
4-cyano-N-(2-{7-[2-(4-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C23H27FN4O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0933017
|
2-cyano-N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C25H29N5O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0942311
|
N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
|
C23H28N4O4S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0942351
|
4-cyano-N-{2-[7-(1H-indol-3-yl)methyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethylbenzenesulfonamide
Show/Hide
|
C24H27N5O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0942352
|
2-cyano-N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
|
C23H25N5O3S
|
1
|
| 1 |
IC50 < 31622.78 nM
|
|
|
|
CP0942353
|
N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-3-fluorobenzenesulfonamide
Show/Hide
|
C23H26F2N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0942354
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N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
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C23H27FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0942355
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N-(4-cyanobenzyl)-2-{7-[2-(4-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethanesulfonamide
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C24H29FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0942356
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N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-1-phenylmethanesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0942357
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4-cyano-N-(2-{7-[2-(4-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
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C24H29FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0942358
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4-cyano-N-(3-{7-[2-(3-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
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C24H29FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0945380
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4-cyano-N-(2-{7-[2-(2-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
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C24H29FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0945381
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N-(3-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)propane-2-sulfonamide
Show/Hide
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C22H34N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0945382
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N-(3-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-3,5-dimethylisoxazole-4-sulfonamide
Show/Hide
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C23H31N5O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0947624
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N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-fluorobenzenesulfonamide
Show/Hide
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C23H27FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0947625
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4-cyano-N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H27N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0947634
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tert-butyl {2-[7-(2-{[(4-fluorophenyl)sulfonyl]amino}ethyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}carbamate
Show/Hide
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C21H33FN4O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0948423
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4-cyano-N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C25H29N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0948424
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2-cyano-N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H27N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0949639
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4-cyano-N-(2-{7-[2-(3,5-dimethyl-1H-pyrazol-1-yl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C22H30N6O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0949653
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4-cyano-N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H26FN5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0950618
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4-cyano-N-(2-{7-[3-(2-fluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953090
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4-cyano-N-{2-[7-(4-cyano-2-fluorobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}-N-methylbenzenesulfonamide
Show/Hide
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C24H26FN5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953092
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4-fluoro-N-{2-[7-(2-phenylethyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C22H28FN3O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953094
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4-Cyano-N-(2-{7-[2-(2,4-difluoro-phenyl)-ethyl]-9-oxa-3,7-diaza-bicyclo[3.3.1]non-3-yl}-ethyl)-N-methyl-benzenesulfonamide
Show/Hide
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C24H28F2N4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953125
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1-methyl-1H-imidazole-4-sulfonamide
Show/Hide
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C22H30N6O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953126
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-2-(trifluoromethoxy)benzenesulfonamide
Show/Hide
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C25H29F3N4O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953127
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4-cyano-N-(2-{7-[3-(3-fluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953128
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N-(3-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-1-phenylmethanesulfonamide
Show/Hide
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C26H34N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953129
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N-(2-{7-[2-(4-chlorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-cyanobenzenesulfonamide
Show/Hide
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C23H27ClN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953130
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N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-2,4-difluorobenzenesulfonamide
Show/Hide
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C23H26F2N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953548
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N-{2-[7-(1-benzofuran-3-ylmethyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}-4-cyanobenzenesulfonamide
Show/Hide
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C24H26N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953549
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4-cyano-N-(2-{7-[(2-methyl-1H-indol-3-yl)methyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C25H29N5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953550
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N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}-3,5-dimethylisoxazole-4-sulfonamide
Show/Hide
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C21H27N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953551
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N-(4-cyanobenzyl)-2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethanesulfonamide
Show/Hide
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C23H25N5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0953552
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3-cyano-N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H26FN5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954598
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4-cyano-N-(3-{7-[3-(4-fluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
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C25H31FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954603
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)methanesulfonamide
Show/Hide
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C19H28N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954605
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4-cyano-N-(2-{7-[3-(4-cyano-2-fluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C25H28FN5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954606
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4-cyano-N-methyl-N-{2-[7-(2-phenylethyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C24H30N4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954610
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4-cyano-N-(2-{7-[3-(2,4-difluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
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C25H30F2N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954612
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N-(4-cyanobenzyl)-N-[(3,5-dimethylisoxazol-4-yl)methyl]-2-{7-[(3,5-dimethylisoxazol-4-yl)methyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethanesulfonamide
Show/Hide
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C28H36N6O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0954613
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N-(3-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-2-fluorobenzenesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0957500
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1-[4-(trifluoromethyl)phenyl]methane-sulfonamide
Show/Hide
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C26H31F3N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0957911
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-fluorobenzenesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0959884
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5-chloro-N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diaza-bicyclo[3.3.1]non-3-yl}ethyl)-1,3-dimethyl-1H-pyrazole-4-sulfonamide
Show/Hide
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C23H31ClN6O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0959885
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N-(4-cyanobenzyl)-2-[7-(2-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethanesulfonamide
Show/Hide
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C24H27N5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0959889
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4-fluoro-N-(2-{7-[2-(3-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C22H27F2N3O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0959890
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4-cyano-N-(2-{7-[3-(4-fluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961108
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N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-1-methyl-1H-imidazole-4-sulfonamide
Show/Hide
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C21H28N6O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961109
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-3,5-dimethylisoxazole-4-sulfonamide
Show/Hide
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C23H31N5O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961110
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4-cyano-N-{2-[7-(4-fluorobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C22H25FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961111
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N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-2,3-dihydro-1-benzofuran-5-sulfonamide
Show/Hide
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C25H30N4O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961112
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4-cyano-N-(2-{7-[2-(2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C23H27FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961113
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N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-3-fluorobenzenesulfonamide
Show/Hide
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C24H29FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961114
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N-(3-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-2,4-difluorobenzenesulfonamide
Show/Hide
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C24H28F2N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961115
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N-(3-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
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C25H32N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961116
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4-cyano-N-(2-{7-[2-(3-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C23H27FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961117
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4-cyano-N-(2-{7-[3-(4-cyano-2,6-difluorophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C25H27F2N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961118
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N-(3-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)-3,5-dimethylisoxazole-4-sulfonamide
Show/Hide
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C24H33N5O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961119
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3-cyano-N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C25H29N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961121
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4-cyano-N-(2-{7-[2-(3,4-difluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
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C24H28F2N4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0961122
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4-cyano-N-(3-{7-[2-(3,4-difluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
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C24H28F2N4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0962778
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3-cyano-N-{2-[7-(4-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C23H25N5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0962779
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N-(2-{7-[2-(4-cyanophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-fluorobenzenesulfonamide
Show/Hide
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C23H27FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0962780
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N-(3-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diaza-bicyclo[3.3.1]non-3-yl}propyl)-N-methylbenzenesulfonamide
Show/Hide
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C25H31FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0962781
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4-cyano-N-{2-[7-(4-cyano-2-fluorobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C23H24FN5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0962782
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4-fluoro-N-(2-{7-[2-(2-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C22H27F2N3O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963505
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4-cyano-N-{2-[7-(2-cyanobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
|
C23H25N5O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963506
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N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-3-fluorobenzenesulfonamide
Show/Hide
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C23H27FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963507
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N-{2-[7-(1,3-benzoxazol-2-ylmethyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}-4-cyanobenzenesulfonamide
Show/Hide
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C23H25N5O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963508
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N-(2-{7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-3,5-dimethylisoxazole-4-sulfonamiide
Show/Hide
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C22H28FN5O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963509
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4-cyano-N-(2-{7-[2-(2,6-difluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
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C24H28F2N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963510
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4-cyano-N-(3-{7-[2-(2-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}propyl)benzenesulfonamide
Show/Hide
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C24H29FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963511
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4-cyano-N-(2-{7-[2-(2,4-difluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C23H26F2N4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0963512
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N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-4-methoxybenzenesulfonamide
Show/Hide
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C24H30N4O5S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967271
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4-cyano-N-{2-[7-(2-phenylethyl)-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C23H28N4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967272
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4-cyano-N-(2-{7-[2-(3-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)-N-methylbenzenesulfonamide
Show/Hide
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C24H29FN4O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967273
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4-fluoro-N-{2-[7-(4-fluorobenzyl)-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl]ethyl}benzenesulfonamide
Show/Hide
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C21H25F2N3O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967274
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4-fluoro-N-(2-{7-[2-(4-fluorophenyl)ethyl]-9-oxa-3,7-diazabicyclo-[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C22H27F2N3O3S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967277
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1-(3-chlorophenyl)-N-(2-{7-[2-(4-cyanophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)methanesulfonamide
Show/Hide
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C23H27ClN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967278
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1-(3-chlorophenyl)-N-(2-{7-[3-(4-cyanophenoxy)propyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)methanesulfonamide
Show/Hide
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C25H31ClN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967279
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4-cyano-N-(2-{7-[4-(difluoromethoxy)benzyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C23H26F2N4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0967280
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4-cyano-N-(2-{7-[2-(4-7-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]non-3-yl}ethyl)benzenesulfonamide
Show/Hide
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C23H27FN4O4S
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1
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| 1 |
IC50 < 31622.78 nM
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CP0374304
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-2-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H31F2N3O2
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1
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| 1 |
Ki = 4.65 nM
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CP0462856
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(2,6-difluorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
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C28H34F4N2O2
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1
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| 1 |
Ki = 5 nM
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CP0430472
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridin-3-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H31F2N3O2
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1
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| 1 |
Ki = 5.07 nM
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CP0402317
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-(pyridin-2-yl)piperidin-1-yl)methanone
Show/Hide
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C27H35F2N3O2
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1
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| 1 |
Ki = 5.84 nM
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CP0374305
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((3R,4S)-1-cyclobutyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C28H34F2N2O2
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1
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| 1 |
Ki = 5.87 nM
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CP0383467
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((3S,4R)-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C24H28F2N2O2
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1
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| 1 |
Ki = 6.65 nM
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CP0845107
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(3R,4R,5S)-1-{[(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}-4-(4-fluorophenyl)-3,5-dimethylpiperidin-4-ol Hydrochloride
Show/Hide
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C28H36ClF3N2O2
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1
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| 1 |
Ki = 7.91 nM
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CP0218850
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6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H26N4O2
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1
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| 1 |
Ki = 63.1 nM
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CP0382003
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7-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H26N4O2
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1
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| 1 |
Ki = 100 nM
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CP0415190
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4-(2,2-difluoroethyl)-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C26H28F2N4O2
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1
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| 1 |
Ki = 398.11 nM
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CP0423701
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8-[3-[4-(2-methylquinolin-5-yl)piperazin-1-yl]propyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 630.96 nM
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CP0126585
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4-methyl-6-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 794.33 nM
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CP0406077
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1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C27H32N4O
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1
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| 1 |
Ki = 794.33 nM
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CP0437527
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5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
Show/Hide
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C28H31FN4O
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1
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| 1 |
Ki = 1258.93 nM
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CP0415189
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4-(cyclopropylmethyl)-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C28H32N4O2
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1
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| 1 |
Ki = 1584.89 nM
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CP0423700
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4-cyclopropyl-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C27H30N4O2
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1
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| 1 |
Ki = 1584.89 nM
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CP0406074
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1,6-dimethyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C28H32N4O
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1
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| 1 |
Ki = 1584.89 nM
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CP0406076
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1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperidin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C28H31N3O
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1
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| 1 |
Ki = 1995.26 nM
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CP0283739
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8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4H-1,4-benzoxazin-3-one
Show/Hide
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C24H26N4O2
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1
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| 1 |
Ki = 2511.89 nM
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CP0502072
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5-[2-[2,2-dimethyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
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C28H32N4O
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1
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| 1 |
Ki = 2511.89 nM
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CP0505428
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5-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,6-dimethylquinolin-2-one
Show/Hide
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C27H29FN4O
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1
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| 1 |
Ki = 2511.89 nM
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CP0322800
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4-methyl-7-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 3162.28 nM
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CP0373427
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8-[3-[(2R)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]propyl]-4-methyl-1,4-benzoxazin-3-one
Show/Hide
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C27H31FN4O2
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1
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| 1 |
Ki = 3162.28 nM
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CP0462326
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8-[2-[(2R)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-4-methyl-1,4-benzoxazin-3-one
Show/Hide
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C26H29FN4O2
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1
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| 1 |
Ki = 3162.28 nM
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CP0406079
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5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C25H28N4O
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1
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| 1 |
Ki = 3162.28 nM
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CP0270386
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4-methyl-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C25H28N4O2
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1
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| 1 |
Ki = 3981.07 nM
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CP0498761
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8-[2-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4-methyl-1,4-benzoxazin-3-one
Show/Hide
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C25H27FN4O2
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1
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| 1 |
Ki = 3981.07 nM
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CP0406080
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1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C26H30N4O
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1
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| 1 |
Ki = 3981.07 nM
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CP0479139
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1,6-dimethyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C27H30N4O
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1
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| 1 |
Ki = 3981.07 nM
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CP0504542
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6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-3,4-dihydro-1H-quinolin-2-one
Show/Hide
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C26H30N4O
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1
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| 1 |
Ki = 3981.07 nM
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CP0291722
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4-methyl-8-[3-[4-(2-methylquinolin-5-yl)piperazin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
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C26H30N4O2
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1
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| 1 |
Ki = 5011.87 nM
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CP0373426
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8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-4-propan-2-yl-1,4-benzoxazin-3-one
Show/Hide
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C27H32N4O2
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1
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| 1 |
Ki = 5011.87 nM
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CP0386021
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6-chloro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C26H27ClN4O
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1
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| 1 |
Ki = 5011.87 nM
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CP0446892
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1-methyl-5-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C27H30N4O
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1
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| 1 |
Ki = 5011.87 nM
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CP0352008
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4-methyl-8-[3-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]propyl]-1,4-benzoxazin-3-one
Show/Hide
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C27H32N4O2
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1
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| 1 |
Ki = 6309.57 nM
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CP0498771
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8-[3-[4-(7-fluoro-2-methylquinolin-5-yl)piperazin-1-yl]propyl]-4-methyl-1,4-benzoxazin-3-one
Show/Hide
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C26H29FN4O2
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1
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| 1 |
Ki = 6309.57 nM
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CP0406075
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5-[2-[(2S)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
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C27H29FN4O
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1
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| 1 |
Ki = 6309.57 nM
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CP0502266
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4-ethyl-8-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C26H30N4O2
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1
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| 1 |
Ki = 7943.28 nM
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CP0502075
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1,6-dimethyl-5-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C28H32N4O
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1
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| 1 |
Ki = 7943.28 nM
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CP0435069
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4-methyl-8-[2-[(2R)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C26H30N4O2
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1
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| 1 |
Ki = 10000 nM
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CP0386020
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1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C26H28N4O
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1
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| 1 |
Ki = 10000 nM
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CP0454396
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5-[2-[(2R)-4-(7-fluoro-2-methylquinolin-5-yl)-2-methylpiperazin-1-yl]ethyl]-1-methylquinolin-2-one
Show/Hide
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C27H29FN4O
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1
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| 1 |
Ki = 10000 nM
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CP0415188
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4-methyl-8-[2-[(2S)-2-methyl-4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1,4-benzoxazin-3-one
Show/Hide
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C26H30N4O2
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1
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| 1 |
Ki = 12589.25 nM
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CP0406078
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6-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
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C26H28N4O
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1
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| 1 |
Ki = 25118.86 nM
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CP0502082
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6-fluoro-1-methyl-5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]quinolin-2-one
Show/Hide
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C26H27FN4O
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1
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| 1 |
Ki = 31622.78 nM
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CP0502083
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5-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]-1H-quinolin-2-one
Show/Hide
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C25H26N4O
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1
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| 1 |
Ki > 31622.78 nM
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CP0402318
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((3R,4S)-4-(2,4-difluorophenyl)-1-(tetrahydro-2H-pyran-4-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C29H36F2N2O3
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1
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| 1 |
Ki > 5.27 nM
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CP0383468
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((3S,4R)-4-(2,4-difluorophenyl)-1-isopropylpyrrolidin-3-yl)((3S,4R,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C27H34F2N2O2
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1
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| 1 |
Ki > 7.88 nM
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CP0374306
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((3R,4S)-1-cyclopropyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C27H32F2N2O2
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1
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| 1 |
Ki > 9.17 nM
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CP0383465
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyrimidin-4-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C28H30F2N4O2
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1
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| 1 |
Ki > 10 nM
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CP0400031
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((3R,4S)-4-(2,4-difluorophenyl)-1-(pyridazin-3-yl)pyrrolidin-3-yl)((3S,4S,5R)-4-hydroxy-3,5-dimethyl-4-phenylpiperidin-1-yl)methanone
Show/Hide
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C28H30F2N4O2
|
1
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| 1 |
Ki > 10 nM
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CP0401418
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((3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl)((3S,4R,5R)-4-(4-chlorophenyl)-4-hydroxy-3,5-dimethylpiperidin-1-yl)methanone
Show/Hide
|
C28H35ClF2N2O2
|
1
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| 1 |
Ki > 10 nM
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CP0845516
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(3R,4R,5S)-1-{[(3S,4R)-4-(2,4-Difluorophenyl)-1-pyridazin-3-ylpyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-propylpiperidin-4-ol Hydrochloride
Show/Hide
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C25H33ClF2N4O2
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1
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| 1 |
Ki > 10 nM
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CP0849935
|
(3R,4R,5S)-4-Cyclopropyl-1-{[(3S,4R)-4-(2,4-difluorophenyl)-1-pyridazin-3-ylpyrrolidin-3-yl]carbonyl}-3,5-dimethylpiperidin-4-ol Hydrochloride
Show/Hide
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C25H31ClF2N4O2
|
1
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| 1 |
Ki > 10 nM
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CP0849936
|
(3R,4R,5S)-1-{[(3S,4R)-1-tert-Butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}-3,5-dimethyl-4-phenylpiperidin-4-ol Hydrochloride
Show/Hide
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C28H37ClF2N2O2
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1
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| 1 |
Ki > 10 nM
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