General Information of the Compound
| Compound ID |
CP0002229
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| Compound Name |
(Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-phenyl)-ethyl]-methylamino}-ethoxy)-phenyl]-methanesulfonamide
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| Synonyms |
1-(4-methanesulfonamidophenoxy)-2-(N-(4-methanesulfonamidophenethyl)-N-methylamine)ethane
1-MSPMPE
Beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide
Dofetilida
Dofetilida [INN-Spanish]
Dofetilide
Dofetilide (JAN/USAN/INN)
Dofetilide [USAN:BAN:INN]
Dofetilidum
Dofetilidum [INN-Latin];Tikosyn (TN)
Methanesulfonamide, N-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)ethyl)amino)ethyl)phenyl)
N-(4-{2-[methyl(2-{4-[(methylsulfonyl)amino]phenoxy}ethyl)amino]ethyl}phenyl)methanesulfonamide
N-[4-[2-[2-[4-(methanesulfonamido)phenoxy]ethyl-methylamino]ethyl]phenyl]methanesulfonamide
Tikosyn
Tikosyn, UK68798, Dofetilide
UK 68,798
UK 68798
UK-68,798
UK-68798
Xelide
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| Structure |
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| Formula |
C19H27N3O5S2
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| Molecular Weight |
441.575
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| Canonical SMILES |
CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1
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| InChI |
InChI=1S/C19H27N3O5S2/c1-22(13-12-16-4-6-17(7-5-16)20-28(2,23)24)14-15-27-19-10-8-18(9-11-19)21-29(3,25)26/h4-11,20-21H,12-15H2,1-3H3
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| InChIKey |
IXTMWRCNAAVVAI-UHFFFAOYSA-N
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| CAS |
115256-11-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Cell-based Assay
Clinical Information about the Compound