Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-(5-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)pyridin-2-yl)-N-ethyl-2,8-diazaspiro[4.5]decane-2-carboxamide
    Show/Hide
 PubChem ID
CID: 24744797
SID: 49638451
Canonical SMILES
CCNC(=O)N1CCC2(C1)CCN(CC2)c1ccc(cn1)C(=O)Nc1cc(ccc1N)-c1cccs1
    Show/Hide
Compound Formula C27H32N6O2S
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 460 nM
   TI
   LI
   LO
   TS