Brief Information of the Compound and Protein
Compound Name
4-chloro-N-[(1R)-1-[(1S,5R)-3-(5,6-difluorobenzimidazol-1-yl)-6-bicyclo[3.1.0]hexanyl]propyl]benzamide
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Canonical SMILES
CC[C@@H](NC(=O)c1ccc(Cl)cc1)[C@@H]1[C@H]2C[C@@H](C[C@@H]12)n1cnc2cc(F)c(F)cc12
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Compound Formula C23H22ClF2N3O
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2400 nM
2 IC50 = 11000 nM