General Information of the Compound
| Compound ID |
CP0035893
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| Compound Name |
(Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine
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| Synonyms |
(+-)-Thioridazine
10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine
10-[2-(1-methyl-2-piperidyl)ethyl]-2-methylsulfanyl-phenothiazine
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylthio)-10H-phenothiazine
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine
3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine
Aldazine
Dl-Thioridazine
Mallorol
Malloryl
Meleril
Mellaril
Mellaril (*Hydrochloride*)
Mellaril (TN)
Mellaril-S
Mellaril-S (TN)
Mellarit
Mellerets
Mellerette
Melleretten
Melleril
Melleril (liquid)
Melleryl
Metlaril
Novoridazine
Novoridazine (TN)
Orsanil
Ridazine
Sonapax
Stalleril
TP-21
Thioridazin
Thioridazine
Thioridazine (USP/INN)
Thioridazine Hcl
Thioridazine Hcl Intensol
Thioridazine [USAN:INN:BAN]
Thioridazine prolongatum
Thioridazine, prolongatum
Thioridazinum
Thioridazinum [INN-Latin]
Thioril (TN)
Thioxidazine
Thoridazine hydrochloride
Tioridazin
Tioridazina
Tioridazina [INN-Spanish]
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| Structure |
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| Formula |
C21H26N2S2
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| Molecular Weight |
370.587
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| Canonical SMILES |
CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1
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| InChI |
InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
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| InChIKey |
KLBQZWRITKRQQV-UHFFFAOYSA-N
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| CAS |
50-52-2
57129-06-3
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01002, Cytochrome P450 1A2
Protein ID: PT01049, Cytochrome P450 2C19
Protein ID: PT00817, Cytochrome P450 2D6
Protein ID: PT06109, Geminin
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT01105, Sodium channel protein type 5 subunit alpha
Protein ID: PT01102, Voltage-dependent L-type calcium channel subunit alpha-1C
Clinical Information about the Compound