Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl N-[4-[4-amino-5-(5-amino-4-chloro-2-fluorophenyl)pyrrolo[2,3-d]pyrimidin-7-yl]-1-bicyclo[2.2.2]octanyl]carbamate
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Canonical SMILES
COC(=O)NC12CCC(CC1)(CC2)n1cc(-c2cc(N)c(Cl)cc2F)c2c(N)ncnc12
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Compound Formula C22H24ClFN6O2
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 6000 nM
   TI
   LI
   LO
   TS
2
IC50 > 30000 nM
   TI
   LI
   LO
   TS