Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3R)-5-fluoro-3-hydroxy-3-[[4-[(4-methyl-2,3-dihydropyrido[3,2-b][1,4]oxazin-6-yl)methylamino]-2-oxabicyclo[2.2.2]octan-1-yl]methyl]-1,7-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7,9-tetraen-11-one
    Show/Hide
 PubChem ID
CID: 118736763
Canonical SMILES
CN1CCOc2ccc(CNC34CCC(C[C@]5(O)Cn6c7c5c(F)cnc7ccc6=O)(CC3)OC4)nc12
    Show/Hide
Compound Formula C27H30FN5O4
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 60000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 > 60000 nM