Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(2-amino-5-thiophen-2-ylphenyl)-6-[2-(2-hydroxyethyl)-2,8-diazaspiro[4.5]decan-8-yl]pyridine-3-carboxamide
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 PubChem ID
CID: 44590016
Canonical SMILES
Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CCN(CCO)C2)CC1)-c1cccs1
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Compound Formula C26H31N5O2S
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 6500 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 170 nM
   TI
   LI
   LO
   TS