General Information of the Compound
| Compound ID |
CP0146498
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| Compound Name |
2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3H)-one
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| Synonyms |
2-((1-(1-(p-Fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3H)-pyrimidinone
2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one
Allphar brand of mizolastine
Galderma brand of mizolastine
MKC-431
Mistalin
Mistamine
Mizolastina
Mizolastina [INN-Spanish]
Mizolastine
Mizolastine (JAN/INN)
Mizolastine [INN]
Mizolastinum
Mizolastinum [INN-Latin]
Mizolen
Mizollen
Mizollen (TN)
Novag brand of mizolastine
SL 85.0324
SL-85.0324
Sanofi Synthelabo brand of mizolastine
Schwarz brand of mizolastine
Zolim
Zolistam
Zolistan
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| Structure |
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| Formula |
C24H25FN6O
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| Molecular Weight |
432.503
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| Canonical SMILES |
CN(C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1)c1nccc(=O)[nH]1
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| InChI |
InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)
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| InChIKey |
PVLJETXTTWAYEW-UHFFFAOYSA-N
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| CAS |
108612-45-9
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT01206, Histamine H1 receptor
Protein ID: PT01310, Muscarinic acetylcholine receptor M1
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Cell-based Assay
Clinical Information about the Compound