General Information of the Compound
| Compound ID |
CP0033565
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| Compound Name |
(+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butan-1-ol
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| Synonyms |
1-(4-tert-Butylphenyl)-4-(4-(alpha-hydroxybenzhydryl)piperidino)-butan-1-ol
1-(4-tert-butylphenyl)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-ol
1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
1-(p-tert-Butylphenyl)-4-(4'-(alpha-hydroxydiphenylmethyl)-1'-piperidyl)butanol
1-[4-(1,1-dimethylethyl)phenyl]-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butan-1-ol
Aldaban
Aliud Brand of Terfenadine
Allerplus
Alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol
Alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenyl-methyl)-1-piperidine butanol
Alpha-(4-[1,1-Dimethylethyl]phenyl)-4-[hydroxydiphenylmethyl]-1-piperidinebutanol
Alpha-(p-tert-Butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Alpha-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol
Balkis Saft Spezial
Bial Brand of Terfenadine
Cantabria Brand of Terfenadine
Ct Arzneimittel Brand of Terfenadine
Ct-Arzneimittel Brand of Terfenadine
Cyater
Dolorgiet Brand of Terfenadine
Heumann Brand of Terfenadine
Hisfedin
Hoechst Brand of Terfenadine
MDL 9918
MDL-9918
Merck dura Brand of Terfenadine
Mundipharma Brand of Terfenadine
RMI 9918
RMI-9918
RMI9918
Rapidal
Ratiopharm Brand of Terfenadine
Seldane
Seldane (TN)
Sigma Tau Brand of Terfenadine
Sigma-Tau Brand of Terfenadine
Stadapharm Brand of Terfenadine
T 9652
Teldane
Teldane (TN)
Teldanex
Terdin
Terfedura
Terfemundin
Terfen
Terfenadin AL
Terfenadin Heumann
Terfenadin Stada
Terfenadin von ct
Terfenadin-ratiopharm
Terfenadina
Terfenadina [INN-Spanish]
Terfenadine
Terfenadine (JAN/USAN/INN)
Terfenadine [USAN:BAN:INN:JAN]
Terfenadinum
Terfenadinum [INN-Latin]
Terfenidine
Terfex
Ternadin
Triludan
Triludan (TN)
Wolff Brand of Terfenadine
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| Structure |
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| Formula |
C32H41NO2
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| Molecular Weight |
471.685
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| Canonical SMILES |
CC(C)(C)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
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| InChI |
InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3
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| InChIKey |
GUGOEEXESWIERI-UHFFFAOYSA-N
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| CAS |
50679-08-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Protein ID: PT06079, ATP-dependent translocase ABCB1
Protein ID: PT01685, ATP-dependent translocase ABCB1
Protein ID: PT02795, Cytochrome P450 2J2
Protein ID: PT01206, Histamine H1 receptor
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Cell-based Assay
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT01105, Sodium channel protein type 5 subunit alpha
Protein ID: PT01102, Voltage-dependent L-type calcium channel subunit alpha-1C
Clinical Information about the Compound