Brief Information of the Compound and Protein
Compound Name
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
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PubChem ID
CID: 135398745
SID: 14923451
Canonical SMILES
CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12
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Compound Formula C17H20N4S
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 181.97 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 36000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 181 nM
2 IC50 = 181.97 nM
3 IC50 = 231.3 nM