| Compound ID |
Compound Name |
Compound Formula |
|
CP0579696
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)amino]-7-methylnaphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
Show/Hide
|
C35H33N3O6S
|
1
|
| 1 |
EC50 = 148 nM
|
|
|
|
CP0575730
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)-methylamino]naphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
Show/Hide
|
C35H33N3O6S
|
1
|
| 1 |
EC50 = 232 nM
|
|
|
|
CP0568564
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)-methylamino]-7-methylnaphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
Show/Hide
|
C36H35N3O6S
|
1
|
| 1 |
EC50 = 260 nM
|
|
|
|
CP0546362
|
3-[4-methoxy-3-[[8-[(3-methoxybenzoyl)amino]naphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
Show/Hide
|
C34H31N3O6S
|
1
|
| 1 |
EC50 = 473 nM
|
|
|
|
CP0571657
|
3-[4-methoxy-3-[[8-[(4-methoxybenzoyl)-methylamino]naphthalen-2-yl]sulfamoyl]phenyl]-N,N-dimethylbenzamide
Show/Hide
|
C35H33N3O6S
|
1
|
| 1 |
EC50 = 654 nM
|
|
|
|
CP0544594
|
3-[3-[(7-benzamidonaphthalen-2-yl)sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C33H29N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0545034
|
3-[3-[[7-[benzoyl(methyl)amino]naphthalen-2-yl]sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C34H31N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0548118
|
3-[3-[(8-benzamidonaphthalen-2-yl)sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C33H29N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0569492
|
N-[7-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]naphthalen-1-yl]-2-methoxy-N-methylbenzamide
Show/Hide
|
C35H33N3O6S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0569538
|
3-[3-[[8-[benzoyl(methyl)amino]naphthalen-2-yl]sulfamoyl]-4-methoxyphenyl]-N,N-dimethylbenzamide
Show/Hide
|
C34H31N3O5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0544498
|
US10287305, Example 5
Show/Hide
|
C21H32N2O5S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0462693
|
1-(3,4-dichlorophenyl)-2-[2-imino-3-[(4-methylphenyl)methyl]benzimidazol-1-yl]ethanol
Show/Hide
|
C23H21Cl2N3O
|
1
|
| 1 |
EC50 > 3200 nM
|
|
|
|
CP0574205
|
N-[2-[3-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]phenyl]ethyl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C33H32N6O5S
|
1
|
| 1 |
EC50 < 35481.34 nM
|
|
|
|
CP0511738
|
N-ethyl-N-[(2S)-1-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 0.767 nM
|
|
|
|
CP0416076
|
N-[[(2S,6S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-6-methylpiperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C27H26FN3O3S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0450686
|
N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C27H27N3O3S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0430613
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H23FN8O
|
1
|
| 1 |
IC50 = 0.82 nM
|
|
|
|
CP0517471
|
N-[[(2S)-5-fluoro-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C26H24FN3O3S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0867328
|
rac-N-((1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)piperidin-2-yl)methyl)benzofuran-4-carboxamide
Show/Hide
|
C26H24FN3O3S
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0478340
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H23FN6O2
|
1
|
| 1 |
IC50 = 1.07 nM
|
|
|
|
CP0425199
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H22FN9O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0478339
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H21FN6O2
|
1
|
| 1 |
IC50 = 1.25 nM
|
|
|
|
CP0389253
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H20F2N6O2
|
1
|
| 1 |
IC50 = 1.26 nM
|
|
|
|
CP0430614
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O2
|
1
|
| 1 |
IC50 = 1.26 nM
|
|
|
|
CP0464870
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C25H24FN5O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0425198
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C24H21F2N5O2
|
1
|
| 1 |
IC50 = 1.58 nM
|
|
|
|
CP0511741
|
N-ethyl-N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 1.62 nM
|
|
|
|
CP0389255
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C24H24FN7O
|
1
|
| 1 |
IC50 = 1.81 nM
|
|
|
|
CP0485630
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-6-methyl-3-(triazol-2-yl)pyridine-2-carboxamide
Show/Hide
|
C22H22FN7O2
|
1
|
| 1 |
IC50 = 1.82 nM
|
|
|
|
CP0389254
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-6-methyl-3-(triazol-2-yl)pyridine-2-carboxamide
Show/Hide
|
C21H22FN9O
|
1
|
| 1 |
IC50 = 1.84 nM
|
|
|
|
CP0475352
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0511739
|
N-ethyl-N-[(2S)-1-[4-(5-fluoropyridin-2-yl)triazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H23FN8O
|
1
|
| 1 |
IC50 = 1.93 nM
|
|
|
|
CP0383668
|
N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0415412
|
N-[[(2S)-5-hydroxy-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H27N3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0542403
|
N-[[(2S,3S)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0549104
|
N-[[(2S)-5,5-difluoro-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H25F2N3O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0444292
|
1-(dibenzofuran-2-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
Show/Hide
|
C26H25NO4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0257370
|
US9242970, 369
Show/Hide
|
C25H22ClNO4
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0495605
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C23H21F2N7O
|
1
|
| 1 |
IC50 = 2.01 nM
|
|
|
|
CP0446902
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H21FN8O
|
1
|
| 1 |
IC50 = 2.45 nM
|
|
|
|
CP0860065
|
(rac)-(2-(3,4-dimethoxybenzyl)piperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C24H28N4O3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0450685
|
N-[[1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H27N3O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0523012
|
6-(2,6-dimethoxyphenyl)-1-[[3-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl]piperidin-2-one
Show/Hide
|
C24H26N2O3S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0349347
|
US9242970, 367
Show/Hide
|
C25H22FNO4
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0475353
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20F2N8O
|
1
|
| 1 |
IC50 = 3.06 nM
|
|
|
|
CP0403779
|
N-ethyl-N-[2-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 3.22 nM
|
|
|
|
CP0478341
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C24H23FN6O2
|
1
|
| 1 |
IC50 = 3.24 nM
|
|
|
|
CP0899802
|
(S)-(2-(3,5-dimethoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0958947
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0464872
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-6-methyl-3-pyrimidin-2-ylpyridine-2-carboxamide
Show/Hide
|
C24H23FN6O2
|
1
|
| 1 |
IC50 = 3.58 nM
|
|
|
|
CP0955590
|
(S)-(2-(3-chloro-4-methoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2O2S
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0542401
|
N-[[1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C26H25N3O3S
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0420706
|
1-(dibenzofuran-2-ylmethyl)-5-(2,6-dimethoxyphenyl)-3-methylpyrrolidin-2-one
Show/Hide
|
C26H25NO4
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0455305
|
N-[(2S)-1-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 4.39 nM
|
|
|
|
CP0455308
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]butan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 4.39 nM
|
|
|
|
CP0497677
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(5-methylpyrazin-2-yl)acetamide
Show/Hide
|
C25H30ClN5O5S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0454803
|
N-[[1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C27H25FN4O2S
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0433078
|
1-(dibenzofuran-2-ylmethyl)-6-(2,4-dimethoxypyridin-3-yl)piperidin-2-one
Show/Hide
|
C25H24N2O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0749809
|
(rac)-(7-(3,4-dimethoxybenzyl)-4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)(1-ethyl-1H-indol-3-yl)methanone
Show/Hide
|
C27H28N2O3S
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0429279
|
N-[2-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 5.54 nM
|
|
|
|
CP0384535
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-(1,5-dimethyl-1H-pyrazol-3-yl)-N-ethylacetamide
Show/Hide
|
C25H32ClN5O5S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0338429
|
[(2S,3R)-2-[(1,3-benzoxazol-2-ylamino)methyl]-3-methylpiperidin-1-yl]-(2-methyl-5-phenyl-1,3-thiazol-4-yl)methanone
Show/Hide
|
C25H26N4O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0385542
|
N-[[1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C27H26N4O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0489816
|
[(2S,6S)-2-[(1,3-benzoxazol-2-ylamino)methyl]-6-methylpiperidin-1-yl]-[5-(4-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]methanone
Show/Hide
|
C25H25FN4O2S
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0534500
|
N-ethyl-N-[(2S)-1-[5-(4-fluorophenyl)tetrazol-2-yl]propan-2-yl]-6-methyl-3-pyrimidin-2-ylpyridine-2-carboxamide
Show/Hide
|
C23H23FN8O
|
1
|
| 1 |
IC50 = 6.15 nM
|
|
|
|
CP0435977
|
[(2S)-5-fluoro-2-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]-(2-methyl-5-phenyl-1,3-thiazol-4-yl)methanone
Show/Hide
|
C23H22F4N4OS
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0513536
|
N-[[(2S,3R)-3-methyl-1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O2S
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0407771
|
2-(N-(6-chloro-3-methylbenzo[d]isothiazol-5-yl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(pyridin-2-yl)acetamide
Show/Hide
|
C25H25ClN4O5S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0517460
|
2-(N-(6-chloro-3-methylbenzo[d]isothiazol-5-yl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(6-methylpyridin-2-yl)acetamide
Show/Hide
|
C26H27ClN4O5S2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0524998
|
N-[[(2S,3R)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-3-methylpiperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H27FN4O2S
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0847455
|
(S)-(5-(2,3-dihydrobenzofuran-5-yl)-2-methylthiazol-4-yl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C26H28N2O4S
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
|
CP0860066
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C23H26N4O3
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0415411
|
N-[[(2S,3R)-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)-3-(trifluoromethyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0420708
|
6-(2,6-dimethoxyphenyl)-1-[(3-pyridin-2-ylphenyl)methyl]piperidin-2-one
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0395535
|
N-ethyl-N-[2-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C22H22FN7O
|
1
|
| 1 |
IC50 = 9.06 nM
|
|
|
|
CP0950972
|
(S)-(5-(3-chlorophenyl)-2-methylthiazol-4-yl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C24H25ClN2O3S
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0475346
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)tetrazol-2-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C20H19F2N9O
|
1
|
| 1 |
IC50 = 9.45 nM
|
|
|
|
CP0470511
|
N-[[(2S,3R)-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)-3-(trifluoromethyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C27H24F3N3O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0458289
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 10.1 nM
|
|
|
|
CP0446901
|
N-ethyl-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)tetrazol-2-yl]propan-2-yl]-5-methyl-2-pyrimidin-2-ylbenzamide
Show/Hide
|
C23H23FN8O
|
1
|
| 1 |
IC50 = 10.6 nM
|
|
|
|
CP0847456
|
(S)-(5-(benzo[d][1,3]dioxol-5-yl)-2-methylthiazol-4-yl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C25H26N2O5S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0874293
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-(3-methoxyphenyl)-2-methylthiazol-4-yl)methanone
Show/Hide
|
C25H28N2O4S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0403091
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(1-methyl-1H-pyrazol-3-yl)acetamide
Show/Hide
|
C24H30ClN5O5S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0426711
|
N-[[(2S,6S)-1-[5-(4-fluorophenyl)-2-methyl-1,3-thiazole-4-carbonyl]-6-methylpiperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H27FN4O2S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0513535
|
(2-methyl-4-phenyl-1,3-thiazol-5-yl)-[2-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C23H23F3N4OS
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0087584
|
(2R)-2-[(1S)-6,7-dimethoxy-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-3,4-dihydro-1H-isoquinolin-2-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C29H31F3N2O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0899804
|
(S)-(2-(3-chloro-4-methylbenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2OS
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0385534
|
[5-(4-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S,6S)-2-methyl-6-[[[5-(trifluoromethyl)pyridin-2-yl]amino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C24H24F4N4OS
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0427137
|
6-(2,6-dimethoxyphenyl)-1-[[3-(triazol-2-yl)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0433079
|
6-(2,6-dimethoxyphenyl)-1-[(2-pyrazol-1-ylpyridin-4-yl)methyl]piperidin-2-one
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0481624
|
6-(2,6-dimethoxyphenyl)-1-[(3-pyrimidin-2-ylphenyl)methyl]piperidin-2-one
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0403321
|
1-(dibenzofuran-2-ylmethyl)-5-(2,6-dimethoxyphenyl)pyrrolidin-2-one
Show/Hide
|
C25H23NO4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0455306
|
N-ethyl-5-fluoro-N-[(2S)-1-[5-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H19F2N7O2
|
1
|
| 1 |
IC50 = 14.7 nM
|
|
|
|
CP0542402
|
2-methyl-N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]-1-benzofuran-4-carboxamide
Show/Hide
|
C28H29N3O3S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0406257
|
[(7R)-4-(4-aminothieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C21H22N8OS
|
2
|
| 1 |
IC50 = 15 nM
|
|
|
| 2 |
Ki = 0.9 nM
|
|
|
|
CP0375881
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[2-fluoro-3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0500846
|
(2R)-2-[(8S)-1-chloro-8-[2-[3,5-difluoro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H26ClF5N4O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0853721
|
(S)-(2-(2H-1,2,3-triazol-2-yl)phenyl)(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)methanone
Show/Hide
|
C22H24N4O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0923118
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(2-(pyrimidin-2-yl)phenyl)methanone
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0403090
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N-ethyl-N-(6-methylpyridin-2-yl)acetamide
Show/Hide
|
C26H31ClN4O5S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0500845
|
(2R)-2-[(8S)-1-chloro-8-[2-[2,3-difluoro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H26ClF5N4O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0519400
|
6-(6-methoxy-2-methyl-1,3-benzoxazol-7-yl)-1-[[3-(2-methyl-1,3-thiazol-4-yl)phenyl]methyl]piperidin-2-one
Show/Hide
|
C25H25N3O3S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0899806
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-(4-methoxyphenyl)-2-methylthiazol-4-yl)methanone
Show/Hide
|
C25H28N2O4S
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0407633
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[3-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0444291
|
6-(2,6-dimethoxyphenyl)-1-[[2-(1,3-thiazol-2-yl)pyridin-4-yl]methyl]piperidin-2-one
Show/Hide
|
C22H23N3O3S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0471509
|
(2R)-2-[(8S)-1-chloro-8-[2-[3-chloro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27Cl2F3N4O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0260680
|
US9242970, 357
Show/Hide
|
C25H23NO5
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0523011
|
5-(2,6-dimethoxyphenyl)-3,3-dimethyl-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0850591
|
(S)-(2-(3,4-dichlorobenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C23H22Cl2N2OS
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0860201
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(3-(m-tolyl)pyrazin-2-yl)methanone
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0406201
|
2-{(5R)-5-Methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}1,3-benzoxazole
Show/Hide
|
C23H24N6O2
|
2
|
| 1 |
IC50 = 24 nM
|
|
|
| 2 |
Ki = 4.1 nM
|
|
|
|
CP0438828
|
2-{(5R)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}5,6,7,8-tetrahydroquinazoline
Show/Hide
|
C23H27N7O
|
2
|
| 1 |
IC50 = 24 nM
|
|
|
| 2 |
Ki = 0.78 nM
|
|
|
|
CP0523013
|
6-(2,6-dimethoxyphenyl)-1-[(2-phenylpyridin-4-yl)methyl]piperidin-2-one
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0406197
|
2-{(5R)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H23N7O
|
2
|
| 1 |
IC50 = 26 nM
|
|
|
| 2 |
Ki = 6.2 nM
|
|
|
|
CP0374351
|
[(7R)-4-(4-aminothieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8OS
|
2
|
| 1 |
IC50 = 26 nM
|
|
|
| 2 |
Ki = 0.5 nM
|
|
|
|
CP0860200
|
(S)-(2-(2-chloro-3-methoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2O2S
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0380172
|
6-Fluoro-2-{(5R)-5-Methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H22FN7O
|
2
|
| 1 |
IC50 = 27 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0426712
|
N-[[(2S)-5-(2-hydroxyethylamino)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C31H32N4O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0406199
|
6,7-Fluoro-2-{(5R)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H21F2N7O
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0406255
|
[(7R)-4-(4-amino-5-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8OS
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0857706
|
(rac)-(2-(3,4-dimethoxybenzyl)piperidin-1-yl)(1-ethyl-1H-indol-3-yl)methanone
Show/Hide
|
C25H30N2O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0930265
|
(rac)-(2-(3,4-dimethoxyphenethyl)piperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C25H30N4O3
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0492690
|
2-(N-(6-chloro-3-methylbenzo[d]isothiazol-5-yl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H26ClN3O5S2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0071506
|
(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)(4-(quinazolin-2-yl)-1,4-diazepan-1-yl)methanone
Show/Hide
|
C23H23N7O
|
2
|
| 1 |
IC50 = 29 nM
|
|
|
| 2 |
Ki = 1.2 nM
|
|
|
|
CP0416554
|
2-{(5R)-5-Methyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C24H25N7O
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
Ki = 0.39 nM
|
|
|
|
CP0449744
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-(2,3,4-trifluorophenyl)ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0455955
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28ClF3N4O
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 31 nM
|
|
|
|
CP0467192
|
[(7R)-4-(4-amino-6-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8OS
|
2
|
| 1 |
IC50 = 31 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0433393
|
(2R)-2-[(8S)-1-chloro-8-[2-[2,5-difluoro-4-(trifluoromethyl)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H26ClF5N4O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0444258
|
5-(2,6-dimethoxyphenyl)-3-methyl-1-[(2-methyl-1,3-benzothiazol-5-yl)methyl]pyrrolidin-2-one
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0481531
|
6-(2,6-dimethoxyphenyl)-1-[(2-methyl-1,3-benzothiazol-5-yl)methyl]piperidin-2-one
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0874292
|
(S)-(2-(2-chloro-5-methoxybenzyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H25ClN2O2S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0899808
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)methanone
Show/Hide
|
C23H25N3O4
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0420703
|
6-(2,6-dimethoxyphenyl)-1-[(6-phenylpyridin-2-yl)methyl]piperidin-2-one
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0899810
|
(S)-(2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methyl)pyrrolidin-1-yl)(2-methyl-5-(m-tolyl)thiazol-4-yl)methanone
Show/Hide
|
C25H26N2O3S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0461641
|
[(7R)-7-methyl-4-(5-methylthieno[2,3-d]pyrimidin-2-yl)-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H25N7OS
|
2
|
| 1 |
IC50 = 37 nM
|
|
|
| 2 |
Ki = 0.3 nM
|
|
|
|
CP0044395
|
1-(2-methyl-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea
Show/Hide
|
C17H13N5O2
|
3
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
Ki = 14 nM
|
|
|
| 3 |
Ki = 18 nM
|
|
|
|
CP0450687
|
N-[[(2S,4R)-4-hydroxy-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H27N3O3
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0375627
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0481620
|
6-(2,6-dimethoxyphenyl)-3-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0510499
|
(3S,5R)-5-(2,6-dimethoxyphenyl)-3-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0257308
|
US9242970, 264
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0449763
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[2-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 45 nM
|
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CP0510521
|
6-(2,6-dimethoxyphenyl)-1-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperidin-2-one
Show/Hide
|
C23H24N2O3S
|
1
|
| 1 |
IC50 = 45 nM
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CP0382727
|
[(7R)-7-methyl-4-(5-methylfuro[2,3-d]pyrimidin-2-yl)-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C23H25N7O2
|
2
|
| 1 |
IC50 = 45 nM
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| 2 |
Ki = 0.2 nM
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CP0946756
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-methyl-2-(1H-pyrazol-1-yl)phenyl)methanone
Show/Hide
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C24H27N3O3
|
1
|
| 1 |
IC50 = 45 nM
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CP0379841
|
[(7R)-4-(4-amino-6-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C23H26N8OS
|
2
|
| 1 |
IC50 = 47 nM
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| 2 |
Ki = 0.4 nM
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CP0326222
|
[(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
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C23H23ClN6O2
|
4
|
| 1 |
IC50 = 50 nM
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| 2 |
Ki = 0.55 nM
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| 3 |
Ki = 0.6 nM
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| 4 |
Ki = 3.09 nM
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CP0404370
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(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[3-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H27ClF4N4O
|
1
|
| 1 |
IC50 = 53 nM
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|
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CP0374353
|
[(7R)-4-(4-amino-5-methylthieno[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H26N8OS
|
2
|
| 1 |
IC50 = 53 nM
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|
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| 2 |
Ki = 0.3 nM
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CP0510500
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6-(6-methoxy-2-methyl-1,3-benzoxazol-7-yl)-1-[(3-phenylphenyl)methyl]piperidin-2-one
Show/Hide
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C27H26N2O3
|
1
|
| 1 |
IC50 = 54 nM
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CP0531086
|
N-[2-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 56.1 nM
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CP0911563
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(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(6-methyl-3-(pyrimidin-2-yl)pyridin-2-yl)methanone
Show/Hide
|
C24H26N4O3
|
1
|
| 1 |
IC50 = 60 nM
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CP0568353
|
N-[(2S)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]-3-methylbutan-2-yl]-N,5-dimethyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C24H26FN7O
|
1
|
| 1 |
IC50 = 61.5 nM
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CP0381238
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(R)-2-((S)-1-ethyl-4-(4-ethylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 63 nM
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CP0950971
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(S)-(2-(benzo[d][1,3]dioxol-5-ylmethyl)pyrrolidin-1-yl)(2-methyl-5-(mtolyl)thiazol-4-yl)methanone
Show/Hide
|
C24H24N2O3S
|
1
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| 1 |
IC50 = 64 nM
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CP0433074
|
6-(2,6-dimethoxyphenyl)-1-[(3-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
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CP0257375
|
US9242970, 261
Show/Hide
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C20H19ClF3NO4
|
1
|
| 1 |
IC50 = 65 nM
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CP0463499
|
[(7R)-4-(5,6-dimethylfuro[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C24H27N7O2
|
2
|
| 1 |
IC50 = 67 nM
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|
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| 2 |
Ki = 0.5 nM
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CP0469076
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
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CP0458629
|
(2R)-2-[(8S)-1-chloro-8-[2-[4-(difluoromethoxy)phenyl]ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H29ClF2N4O2
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0089014
|
US9242970, 260
Show/Hide
|
C20H19F4NO4
|
1
|
| 1 |
IC50 = 75 nM
|
|
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CP0510524
|
6-(2,6-dimethoxyphenyl)-1-(naphthalen-2-ylmethyl)piperidin-2-one
Show/Hide
|
C24H25NO3
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0530463
|
US9242970, 406
Show/Hide
|
C24H19F2NO3
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
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CP0415023
|
(2R)-2-[(8S)-3-ethyl-1-methylsulfanyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4OS
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0099204
|
US9242970, 408
Show/Hide
|
C24H19ClFNO3
|
1
|
| 1 |
IC50 = 86 nM
|
|
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CP0510325
|
N-ethyl-N-[(2R)-1-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C23H24FN7O
|
1
|
| 1 |
IC50 = 86.6 nM
|
|
|
|
CP0514118
|
(2R)-2-[(8S)-1-chloro-3-methyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
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CP0375625
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28ClF3N4O
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0435431
|
[(7R)-7-methyl-4-(1-methylpyrazolo[3,4-d]pyrimidin-6-yl)-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H25N9O
|
2
|
| 1 |
IC50 = 92 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0407634
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[2-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H27ClF4N4O
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0510520
|
5-(2,6-dimethoxyphenyl)-3-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0390058
|
2-(1-ethyl-3-methyl-4-(4-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0874291
|
(rac)-(2-(3-methoxyphenethyl)piperidin-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C24H28N4O2
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0895799
|
(S)-(2-(3,4-dimethoxybenzyl)pyrrolidin-1-yl)(5-(4-fluorophenyl)-2-methylthiazol-4-yl)methanone
Show/Hide
|
C24H25FN2O3S
|
1
|
| 1 |
IC50 = 111 nM
|
|
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CP0474343
|
2-(N-(2-chloro-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H30ClN3O5S
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
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CP0382726
|
[(7R)-4-(1,3-dimethylpyrazolo[3,4-d]pyrimidin-6-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H27N9O
|
2
|
| 1 |
IC50 = 119 nM
|
|
|
| 2 |
Ki = 0.8 nM
|
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|
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CP0395536
|
N-[2-[3-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C20H18FN7O
|
1
|
| 1 |
IC50 = 119 nM
|
|
|
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CP0522520
|
N-[[(2S)-5-amino-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C27H27N5O2S
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0444260
|
US9242970, 259
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
|
CP0501338
|
(R)-2-((S)-1-ethyl-3-methyl-4-(4-(trifluoromethyl)phenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0850587
|
(rac)-(7-(3,4-dimethoxybenzyl)-4,5-dihydrothieno[2,3-c]pyridin-6(7H)-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone
Show/Hide
|
C26H26N4O3S
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0447532
|
(2R)-2-[3-ethyl-1-methoxy-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O2
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0420709
|
6-(2,6-dimethoxyphenyl)-1-[[3-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 136 nM
|
|
|
|
CP0481622
|
6-(2,4-dimethoxypyridin-3-yl)-1-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperidin-2-one
Show/Hide
|
C22H23N3O3S
|
1
|
| 1 |
IC50 = 141 nM
|
|
|
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CP0444288
|
6-(2,6-dimethoxyphenyl)-1-[1-[4-(trifluoromethoxy)phenyl]ethyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0044586
|
3-methoxy-2-methyl-N-[[(2S,3R)-3-methyl-1-(2-methyl-5-phenyl-1,3-thiazole-4-carbonyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C27H31N3O3S
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0426709
|
N-[[(2S,4S)-4-fluoro-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C29H26FN3O2
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0385828
|
(2R)-2-[1-ethenyl-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C28H31F3N4O
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0444287
|
6-(2,6-dimethoxyphenyl)-1-(quinolin-6-ylmethyl)piperidin-2-one
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 154 nM
|
|
|
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CP0433056
|
2-(2,6-dimethoxyphenyl)-3-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-thiazolidin-4-one
Show/Hide
|
C19H18F3NO4S
|
1
|
| 1 |
IC50 = 155 nM
|
|
|
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CP0501697
|
(R)-2-((S)-1-ethyl-4-(4-isopropylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 161 nM
|
|
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CP0502219
|
2-(N-(2-cyano-5-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H30N4O5S
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
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CP0427131
|
6-(2,6-dimethoxyphenyl)-1-[(4-propoxyphenyl)methyl]piperidin-2-one
Show/Hide
|
C23H29NO4
|
1
|
| 1 |
IC50 = 169 nM
|
|
|
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CP0455954
|
(2R)-2-[(8S)-1-chloro-3-cyclopropyl-8-[2-[4-(difluoromethoxy)-3-fluorophenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28ClF3N4O2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0192297
|
US9242970, 257
Show/Hide
|
C20H19ClF3NO4
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
|
CP0498935
|
2-(1-ethyl-3-methyl-4-(3-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0481851
|
US9242970, 254
Show/Hide
|
C21H22F3NO5
|
1
|
| 1 |
IC50 = 191 nM
|
|
|
|
CP0257369
|
5-(2,6-dimethoxyphenyl)-3,3-difluoro-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C20H18F5NO4
|
1
|
| 1 |
IC50 = 193 nM
|
|
|
|
CP0379839
|
[(7R)-4-(4-amino-5-methylfuro[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[5-methyl-2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C23H26N8O2
|
2
|
| 1 |
IC50 = 195 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0484191
|
[(7R)-4-(4-amino-5-methylfuro[2,3-d]pyrimidin-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H24N8O2
|
2
|
| 1 |
IC50 = 195 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0382728
|
[(7R)-4-(1,3-dimethylpyrazolo[3,4-d]pyrimidin-6-yl)-7-methyl-1,4-diazepan-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H25N9O
|
2
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
Ki = 4.5 nM
|
|
|
|
CP0488939
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[4-(trifluoromethoxy)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O2
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0420711
|
6-(2-ethoxy-6-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 216 nM
|
|
|
|
CP0481617
|
6-(2,6-dimethoxyphenyl)-1-[(3-phenoxyphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
IC50 = 225 nM
|
|
|
|
CP0455307
|
N-[(2S)-1-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]propan-2-yl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C21H20FN7O
|
1
|
| 1 |
IC50 = 245 nM
|
|
|
|
CP0519407
|
7-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]azepan-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 264 nM
|
|
|
|
CP0099206
|
US9242970, 412
Show/Hide
|
C24H20FNO4
|
1
|
| 1 |
IC50 = 264 nM
|
|
|
|
CP0401034
|
(6R)-4-(benzenesulfonyl)-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C20H22FN3O4S
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0422520
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
|
CP0462019
|
6-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C21H22F3NO4
|
1
|
| 1 |
IC50 = 284 nM
|
|
|
|
CP0367354
|
US9242970, 255
Show/Hide
|
C20H19F4NO4
|
1
|
| 1 |
IC50 = 299 nM
|
|
|
|
CP0473217
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[[3-(trifluoromethyl)phenoxy]methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 312 nM
|
|
|
|
CP0415021
|
(2R)-2-[(8S)-1-chloro-3-propan-2-yl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H30ClF3N4O
|
1
|
| 1 |
IC50 = 313 nM
|
|
|
|
CP0444257
|
1-[[4-(trifluoromethoxy)phenyl]methyl]-6-(2,4,6-trimethoxyphenyl)piperidin-2-one
Show/Hide
|
C22H24F3NO5
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0415022
|
3-ethyl-N,N-dimethyl-7-[(1R)-2-(methylamino)-2-oxo-1-phenylethyl]-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
Show/Hide
|
C29H34F3N5O2
|
1
|
| 1 |
IC50 = 344 nM
|
|
|
|
CP0460925
|
2-(1-ethyl-3-methyl-4-(3-(trifluoromethyl)phenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O
|
1
|
| 1 |
IC50 = 358 nM
|
|
|
|
CP0517187
|
US9828368, Example 57
Show/Hide
|
C26H25N5O4
|
1
|
| 1 |
IC50 = 359 nM
|
|
|
|
CP0488938
|
(2R)-2-[(8S)-1-chloro-3-ethyl-8-[2-[4-fluoro-3-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 378 nM
|
|
|
|
CP0524799
|
N-[[(2S,4R)-4-methoxy-1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C28H28N4O3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0401810
|
2-(1-ethyl-4-(3-fluorophenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H31FN4O
|
1
|
| 1 |
IC50 = 402 nM
|
|
|
|
CP0420707
|
5-(2,6-dimethoxyphenyl)-4-[[4-(trifluoromethoxy)phenyl]methyl]morpholin-3-one
Show/Hide
|
C20H20F3NO5
|
1
|
| 1 |
IC50 = 412 nM
|
|
|
|
CP0404372
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[[4-(trifluoromethyl)phenoxy]methyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C25H26ClF3N4O2
|
1
|
| 1 |
IC50 = 431 nM
|
|
|
|
CP0415024
|
(2R)-2-[(8S)-1-chloro-3-propyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H30ClF3N4O
|
1
|
| 1 |
IC50 = 459 nM
|
|
|
|
CP0367356
|
(3R)-1-(dibenzofuran-2-ylmethyl)-5-(2-fluoro-6-methoxyphenyl)-3-hydroxypyrrolidin-2-one
Show/Hide
|
C24H20FNO4
|
1
|
| 1 |
IC50 = 467 nM
|
|
|
|
CP0455265
|
3-ethyl-N-methyl-7-[(1R)-2-(methylamino)-2-oxo-1-phenylethyl]-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
Show/Hide
|
C28H32F3N5O2
|
1
|
| 1 |
IC50 = 492 nM
|
|
|
|
CP0510525
|
6-(2,6-dimethoxyphenyl)-1-[(4-phenoxyphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
IC50 = 531 nM
|
|
|
|
CP0385827
|
(2R)-2-[1-cyano-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28F3N5O
|
1
|
| 1 |
IC50 = 537 nM
|
|
|
|
CP0420701
|
6-(2,6-dimethoxyphenyl)-4-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 537 nM
|
|
|
|
CP0375626
|
(2R)-2-[(8R)-1-chloro-3-ethyl-8-[2-[3-fluoro-4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H27ClF4N4O
|
1
|
| 1 |
IC50 = 547 nM
|
|
|
|
CP0525371
|
6-(2,6-diethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C23H26F3NO4
|
1
|
| 1 |
IC50 = 550 nM
|
|
|
|
CP0472559
|
[(2R,5R)-5-[4-[(dimethylamino)methyl]-5-phenyl-1,3-oxazol-2-yl]-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C27H30N6O2
|
1
|
| 1 |
IC50 = 557 nM
|
|
|
|
CP0283391
|
US9242970, 263
Show/Hide
|
C22H24F3NO4
|
1
|
| 1 |
IC50 = 619 nM
|
|
|
|
CP0429742
|
2-(1-ethyl-4-(2-fluorophenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H31FN4O
|
1
|
| 1 |
IC50 = 669 nM
|
|
|
|
CP0433055
|
6-(2,6-dimethoxyphenyl)-1-(quinolin-3-ylmethyl)piperidin-2-one
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 675 nM
|
|
|
|
CP0483778
|
(2R)-2-[3-ethyl-1-iodo-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28F3IN4O
|
1
|
| 1 |
IC50 = 717 nM
|
|
|
|
CP0379107
|
5-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C20H20F3NO4
|
1
|
| 1 |
IC50 = 724 nM
|
|
|
|
CP0384011
|
2-(1-ethyl-3-methyl-4-(4-(trifluoromethyl)benzyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H29F3N4O
|
1
|
| 1 |
IC50 = 769 nM
|
|
|
|
CP0472558
|
[(2R,5R)-5-[4-(2-hydroxypropan-2-yl)-5-methyl-1,3-oxazol-2-yl]-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Show/Hide
|
C22H27N5O3
|
1
|
| 1 |
IC50 = 815 nM
|
|
|
|
CP0525953
|
2-(N-(2-cyano-4-methylphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C22H27N3O5S
|
1
|
| 1 |
IC50 = 886 nM
|
|
|
|
CP0474344
|
2-(N-(2-chloro-5-isopropylphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H31ClN2O5S
|
1
|
| 1 |
IC50 = 888 nM
|
|
|
|
CP0510326
|
US9242970, 253
Show/Hide
|
C20H20F3NO5
|
1
|
| 1 |
IC50 = 899 nM
|
|
|
|
CP0511742
|
N-[2-[4-(5-fluoropyridin-2-yl)pyrazol-1-yl]ethyl]-5-methyl-2-(triazol-2-yl)benzamide
Show/Hide
|
C20H18FN7O
|
1
|
| 1 |
IC50 = 908 nM
|
|
|
|
CP0089015
|
US9242970, 258
Show/Hide
|
C20H20F3NO5
|
1
|
| 1 |
IC50 = 927 nM
|
|
|
|
CP0501339
|
2-(4-(4-chlorophenethyl)-1-ethyl-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C26H31ClN4O
|
1
|
| 1 |
IC50 = 993 nM
|
|
|
|
CP0381233
|
2-(1-ethyl-3-methyl-4-(2-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 1031 nM
|
|
|
|
CP0474053
|
(2R)-2-[(8S)-3-ethyl-1-(trifluoromethyl)-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H28F6N4O
|
1
|
| 1 |
IC50 = 1066 nM
|
|
|
|
CP0517212
|
methyl 1-methyl-2-[2-[(3R,6R)-6-methyl-1-[2-(triazol-2-yl)benzoyl]piperidin-3-yl]-1,3-oxazol-4-yl]cyclopropane-1-carboxylate
Show/Hide
|
C24H27N5O4
|
1
|
| 1 |
IC50 = 1080 nM
|
|
|
|
CP0427138
|
6-(2,6-dimethoxyphenyl)-1-[(4-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 1086 nM
|
|
|
|
CP0503013
|
2-(N-(2-chloro-5-methylphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C21H27ClN2O5S
|
1
|
| 1 |
IC50 = 1107 nM
|
|
|
|
CP0444259
|
4-(2,6-dimethoxyphenyl)-3-[[4-(trifluoromethoxy)phenyl]methyl]-3-azabicyclo[3.1.0]hexan-2-one
Show/Hide
|
C21H20F3NO4
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0308272
|
(3S,5R)-1-(dibenzofuran-2-ylmethyl)-5-(2-fluoro-6-methoxyphenyl)-3-hydroxypyrrolidin-2-one
Show/Hide
|
C24H20FNO4
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0510523
|
6-(2-fluoro-6-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C20H19F4NO3
|
1
|
| 1 |
IC50 = 1249 nM
|
|
|
|
CP0481615
|
6-(2,6-dimethoxyphenyl)-4-methyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperazin-2-one
Show/Hide
|
C21H23F3N2O4
|
1
|
| 1 |
IC50 = 1270 nM
|
|
|
|
CP0492689
|
2-(N-(2-chloro-5-(ethyl(methyl)amino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C23H32ClN3O5S
|
1
|
| 1 |
IC50 = 1373 nM
|
|
|
|
CP0421235
|
ethyl 2-[2-[[5-[[(3,5-dimethoxybenzoyl)amino]methyl]-4-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]propanoylamino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
Show/Hide
|
C32H35N5O7S2
|
3
|
| 1 |
IC50 = 1400 nM
|
|
|
| 2 |
Ki = 800 nM
|
|
|
| 3 |
Ki = 7000 nM
|
|
|
|
CP0433077
|
6-(2,6-dimethoxyphenyl)-3,3-dimethyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C23H26F3NO4
|
1
|
| 1 |
IC50 = 1407 nM
|
|
|
|
CP0450359
|
(R)-2-((R)-1-ethyl-4-(4-ethylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C28H36N4O
|
1
|
| 1 |
IC50 = 1424 nM
|
|
|
|
CP0385829
|
(2R)-2-[(8S)-1-chloro-3-(cyclopropylmethyl)-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C28H30ClF3N4O
|
1
|
| 1 |
IC50 = 1426 nM
|
|
|
|
CP0390759
|
4-(3,4-dimethoxyphenyl)sulfonyl-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C22H26FN3O6S
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0480713
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-methylpyridin-3-yl)-2-phenylbenzamide
Show/Hide
|
C27H25N3O3
|
2
|
| 1 |
IC50 = 1542 nM
|
|
|
| 2 |
Ki = 1000 nM
|
|
|
|
CP0427134
|
1-[[4-(trifluoromethoxy)phenyl]methyl]-2-(2,4,6-trimethoxyphenyl)piperidine
Show/Hide
|
C22H26F3NO4
|
1
|
| 1 |
IC50 = 1590 nM
|
|
|
|
CP0390766
|
4-(benzenesulfonyl)-8-quinoxalin-2-yl-1-oxa-4,8-diazaspiro[4.5]decane
Show/Hide
|
C21H22N4O3S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0475652
|
6-fluoro-4-(4-methoxyphenyl)sulfonyl-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C21H24FN3O5S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0474074
|
(2R)-2-[(8S)-1-chloro-3-(methoxymethyl)-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C26H28ClF3N4O2
|
1
|
| 1 |
IC50 = 1645 nM
|
|
|
|
CP0415025
|
(2R)-2-[(8S)-3-ethyl-1-methylsulfonyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
|
C27H31F3N4O3S
|
1
|
| 1 |
IC50 = 1677 nM
|
|
|
|
CP0398948
|
2-(N-(2-chloro-5-(1H-pyrrol-1-yl)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C24H28ClN3O5S
|
1
|
| 1 |
IC50 = 1709 nM
|
|
|
|
CP0481613
|
6-(2,6-dimethoxyphenyl)-4,4-dimethyl-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
Show/Hide
|
C23H26F3NO4
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0421237
|
N-[(Z)-anthracen-9-ylmethylideneamino]-6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-amine
Show/Hide
|
C25H18N6
|
3
|
| 1 |
IC50 = 1900 nM
|
|
|
| 2 |
Ki = 1100 nM
|
|
|
| 3 |
Ki = 16200 nM
|
|
|
|
CP0471479
|
(R)-2-((R)-1-ethyl-4-(4-isopropylphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 1919 nM
|
|
|
|
CP0420704
|
6-(2,6-dimethoxyphenyl)-1-[(2-phenylphenyl)methyl]piperidin-2-one
Show/Hide
|
C26H27NO3
|
1
|
| 1 |
IC50 = 1950 nM
|
|
|
|
CP0411242
|
US8592457, 1-16
Show/Hide
|
C26H23FN4O3
|
2
|
| 1 |
IC50 = 1950 nM
|
|
|
| 2 |
Ki = 4000 nM
|
|
|
|
CP0260679
|
(3R,5S)-3-amino-5-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C20H21F3N2O4
|
1
|
| 1 |
IC50 = 1980 nM
|
|
|
|
CP0064716
|
US8592457, 7-5
Show/Hide
|
C23H21N5O3S
|
2
|
| 1 |
IC50 = 1986 nM
|
|
|
| 2 |
Ki = 3600 nM
|
|
|
|
CP0379054
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-methylpyridin-3-yl)-2-phenylpyridine-3-carboxamide
Show/Hide
|
C26H24N4O3
|
2
|
| 1 |
IC50 = 2005 nM
|
|
|
| 2 |
Ki = 720 nM
|
|
|
|
CP0421239
|
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[[4-(furan-2-ylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C21H18N4O4S2
|
3
|
| 1 |
IC50 = 2200 nM
|
|
|
| 2 |
Ki = 1200 nM
|
|
|
| 3 |
Ki = 6000 nM
|
|
|
|
CP0399393
|
6-fluoro-4-(3-methoxyphenyl)sulfonyl-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C21H24FN3O5S
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0384610
|
(2R)-1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
Show/Hide
|
C24H26N2O4
|
2
|
| 1 |
IC50 = 2300 nM
|
|
|
| 2 |
Ki = 1300 nM
|
|
|
|
CP0499780
|
(3R,5S)-5-(2,6-dimethoxyphenyl)-3-(methylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Show/Hide
|
C21H23F3N2O4
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0427133
|
1-benzyl-6-(2,6-dimethoxyphenyl)piperidin-2-one
Show/Hide
|
C20H23NO3
|
1
|
| 1 |
IC50 = 2423 nM
|
|
|
|
CP0503025
|
2-(N-(2-chloro-5-(trifluoromethyl)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C21H24ClF3N2O5S
|
1
|
| 1 |
IC50 = 2486 nM
|
|
|
|
CP0431186
|
(6S)-4-(benzenesulfonyl)-6-fluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C20H22FN3O4S
|
1
|
| 1 |
IC50 = 2500 nM
|
|
|
|
CP0492699
|
2-(N-(2-chloro-5-(pyrrolidin-1-yl)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
Show/Hide
|
C24H32ClN3O5S
|
1
|
| 1 |
IC50 = 2527 nM
|
|
|
|
CP0444256
|
4-(2,6-dimethoxyphenyl)-3-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-oxazolidin-2-one
Show/Hide
|
C19H18F3NO5
|
1
|
| 1 |
IC50 = 2649 nM
|
|
|
|
CP0472561
|
US9828368, Example 27
Show/Hide
|
C22H30N2O4
|
1
|
| 1 |
IC50 = 2650 nM
|
|
|
|
CP0420702
|
6-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperazin-2-one
Show/Hide
|
C20H21F3N2O4
|
1
|
| 1 |
IC50 = 2680 nM
|
|
|
|
CP0088912
|
US8592457, 1-5
Show/Hide
|
C26H24N4O3
|
2
|
| 1 |
IC50 = 2800 nM
|
|
|
| 2 |
Ki = 2700 nM
|
|
|
|
CP0413404
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(2-fluorophenyl)-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
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C26H23FN4O3
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2
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| 1 |
IC50 = 3000 nM
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| 2 |
Ki = 8600 nM
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CP0349345
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US9242970, 262
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C21H22F3NO5
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1
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| 1 |
IC50 = 3380 nM
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CP0420705
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6-(2-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
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C20H20F3NO3
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1
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| 1 |
IC50 = 3486 nM
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CP0349346
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(3R,5S)-5-(2,6-dimethoxyphenyl)-3-(dimethylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
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C22H25F3N2O4
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1
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| 1 |
IC50 = 3620 nM
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CP0461652
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(2R)-2-[(8S)-1-chloro-8-[2-(4-cyanophenyl)ethyl]-3-ethyl-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
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C26H28ClN5O
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1
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| 1 |
IC50 = 3902 nM
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CP0481852
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(3S,5S)-5-(2,6-dimethoxyphenyl)-3-ethoxy-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
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C22H24F3NO5
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1
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| 1 |
IC50 = 3960 nM
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CP0474075
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(2R)-2-[1-ethoxy-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
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C28H33F3N4O2
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1
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| 1 |
IC50 = 3980 nM
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CP0426829
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(2R)-2-[(8S)-1-cyclopropyl-3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
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C29H33F3N4O
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1
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| 1 |
IC50 = 4171 nM
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CP0481619
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6-(2-methoxy-6-methylphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
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C21H22F3NO3
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1
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| 1 |
IC50 = 4385 nM
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CP0398043
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyridin-2-ylpyridine-4-carboxamide
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C25H23N5O3
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2
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| 1 |
IC50 = 4650 nM
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| 2 |
Ki = 7900 nM
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CP0421240
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N'-(2,5-dichlorophenyl)-2-hydroxy-2,2-bis(4-methylphenyl)acetohydrazide
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C22H20Cl2N2O2
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3
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| 1 |
IC50 = 4800 nM
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| 2 |
Ki = 2700 nM
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| 3 |
Ki = 10300 nM
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CP0403089
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2-(N-(5-chloro-2-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C22H30ClN3O5S
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1
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| 1 |
IC50 = 4875 nM
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CP0420712
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6-(2-chloro-6-methoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]piperidin-2-one
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C20H19ClF3NO3
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1
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| 1 |
IC50 = 4883 nM
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CP0248144
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(3S,5S)-5-(2,6-dimethoxyphenyl)-3-(methylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
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C21H23F3N2O4
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1
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| 1 |
IC50 = 5780 nM
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CP0499682
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4-(benzenesulfonyl)-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
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C20H23N3O4S
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1
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| 1 |
IC50 = 6300 nM
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CP0308200
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(3S,5S)-3-amino-5-(2,6-dimethoxyphenyl)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
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C20H21F3N2O4
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1
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| 1 |
IC50 = 7030 nM
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CP0367355
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(3S,5S)-5-(2,6-dimethoxyphenyl)-3-(dimethylamino)-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
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C22H25F3N2O4
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1
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| 1 |
IC50 = 8720 nM
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CP0481618
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6-(2,6-dimethoxyphenyl)-1-(2-phenylethyl)piperidin-2-one
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C21H25NO3
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1
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| 1 |
IC50 = 9704 nM
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CP0517188
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(4-(2H-1,2,3-triazol-2-yl)thiophen-3- yl)((2R,5R)-5-(4-((S)-2-hydroxybutan-2- yl)-5-methyloxazol-2-yl)-2- methylpiperidin-1-yl)methanone
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C21H27N5O3S
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1
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| 1 |
IC50 = 9770 nM
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CP0398947
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2-(N-(5-(dimethylamino)-2-methoxyphenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C23H33N3O6S
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1
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| 1 |
IC50 > 10000 nM
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CP0412312
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N,N-diethyl-2-(N-(3-fluorophenyl)sulfonyl-4-methylanilino)acetamide
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C19H23FN2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0412313
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2-(N-(2-cyano-3-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C23H30N4O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0422493
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2-(4-cyano-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C20H23N3O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0422494
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N,N-diethyl-2-(4-methyl-N-(3-methylphenyl)sulfonylanilino)acetamide
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C20H26N2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0474340
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2-(3,4-dimethoxy-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C21H28N2O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0474341
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2-(4-bromo-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C19H23BrN2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0474342
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2-(2-chloro-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C19H23ClN2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0490181
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N,N-diethyl-2-(4-methyl-N-(2-methylphenyl)sulfonylanilino)acetamide
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C20H26N2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0492691
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N,N-diethyl-2-(N-(4-methoxyphenyl)sulfonyl-4-methylanilino)acetamide
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C20H26N2O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0492692
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N,N-diethyl-2-(N-(2-fluorophenyl)sulfonyl-4-methylanilino)acetamide
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C19H23FN2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0497675
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N,N-diethyl-2-(N-(4-ethylphenyl)sulfonyl-4-methylanilino)acetamide
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C21H28N2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0497676
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N,N-diethyl-2-(4-methyl-N-[4-(trifluoromethoxy)phenyl]sulfonylanilino)acetamide
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C20H23F3N2O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0502220
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2-(N-(2-chloro-5-cyanophenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C21H24ClN3O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0502543
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2-(N-(4-chloro-3-(dimethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C22H30ClN3O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0502544
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N,N-diethyl-2-(4-methyl-N-(4-methylphenyl)sulfonylanilino)acetamide
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C20H26N2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0503014
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2-(N-(2-chloro-5-(diethylamino)phenyl)-3,4-dimethoxyphenylsulfonamido)-N,N-diethylacetamide
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C24H34ClN3O5S
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1
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| 1 |
IC50 > 10000 nM
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CP0503024
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2-(3-chloro-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C19H23ClN2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0517461
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N,N-diethyl-2-(N-(4-fluorophenyl)sulfonyl-4-methylanilino)acetamide
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C19H23FN2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0554114
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2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide
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C23H32N2O3S
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1
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| 1 |
IC50 > 10000 nM
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CP0381235
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2-(1-ethyl-4-(4-methoxyphenethyl)-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
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C27H34N4O2
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1
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| 1 |
IC50 = 10000 nM
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CP0401811
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(R)-2-((R)-1-ethyl-3-methyl-4-(p-tolyloxymethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide
Show/Hide
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C26H32N4O2
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1
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| 1 |
IC50 = 10000 nM
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CP0399392
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4-(benzenesulfonyl)-6,6-difluoro-N-phenyl-1-oxa-4,8-diazaspiro[4.5]decane-8-carboxamide
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C20H21F2N3O4S
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1
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| 1 |
IC50 > 10000 nM
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CP0426830
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(2R)-2-[3-ethyl-1-propyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C29H35F3N4O
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1
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| 1 |
IC50 = 10000 nM
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CP0447530
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3-ethyl-7-[(1R)-2-(methylamino)-2-oxo-1-phenylethyl]-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazine-1-carboxamide
Show/Hide
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C27H30F3N5O2
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1
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| 1 |
IC50 = 10000 nM
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CP0473366
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(2R)-2-[3-ethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C26H29F3N4O
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1
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| 1 |
IC50 = 10000 nM
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CP0474052
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(2R)-2-[3-ethyl-1-methyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C27H31F3N4O
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1
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| 1 |
IC50 = 10000 nM
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CP0474054
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(2R)-2-[3-ethyl-1-propan-2-yl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C29H35F3N4O
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1
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| 1 |
IC50 = 10000 nM
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CP0480150
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(2R)-2-[1,3-diethyl-8-[2-[4-(trifluoromethyl)phenyl]ethyl]-6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl]-N-methyl-2-phenylacetamide
Show/Hide
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C28H33F3N4O
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1
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| 1 |
IC50 = 10000 nM
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CP0420710
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6-(2,6-dimethoxyphenyl)-1-phenylpiperidin-2-one
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C19H21NO3
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1
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| 1 |
IC50 > 10000 nM
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CP0523010
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3-(2,6-dimethoxyphenyl)-2-[[4-(trifluoromethoxy)phenyl]methyl]-3H-isoindol-1-one
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C24H20F3NO4
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1
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| 1 |
IC50 > 10000 nM
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CP0378607
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyrazin-2-ylpyridine-4-carboxamide
Show/Hide
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C24H22N6O3
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 31000 nM
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CP0379053
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyrrolidin-1-ylpyridine-4-carboxamide
Show/Hide
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C24H27N5O3
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 14000 nM
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CP0398042
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5-(azetidin-1-yl)-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
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C23H25N5O3
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 18000 nM
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CP0398145
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxamide
Show/Hide
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C27H23N5O4
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 4100 nM
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CP0399524
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-phenylpyrimidine-4-carboxamide
Show/Hide
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C25H23N5O3
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 23000 nM
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CP0413403
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenylpyridazine-4-carboxamide
Show/Hide
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C25H23N5O3
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 15000 nM
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CP0415926
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(1-methylpyrazol-4-yl)-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
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C24H24N6O3
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 930 nM
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CP0415927
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-5-(5-fluoropyridin-3-yl)-2-(5-methylpyridin-3-yl)pyridine-4-carboxamide
Show/Hide
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C25H22FN5O3
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 17000 nM
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CP0433581
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-4-(3-fluorophenyl)-2-(5-methylpyridin-3-yl)-1,3-thiazole-5-carboxamide
Show/Hide
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C24H21FN4O3S
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2
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| 1 |
IC50 > 10000 nM
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| 2 |
Ki = 12000 nM
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CP0473839
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-morpholin-4-ylpyridine-4-carboxamide
Show/Hide
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C24H27N5O4
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2
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| 1 |
IC50 = 10000 nM
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| 2 |
Ki = 1500 nM
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CP0421234
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2-(N-(3,4-dimethoxyphenyl)sulfonyl-4-methoxyanilino)-N-(1-phenylethyl)acetamide
Show/Hide
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C25H28N2O6S
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3
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| 1 |
IC50 = 11100 nM
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| 2 |
Ki = 6300 nM
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| 3 |
Ki = 46700 nM
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CP0421233
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2-[2-(4-amino-1,2,5-oxadiazol-3-yl)benzimidazol-1-yl]-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
Show/Hide
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C21H22N6O4
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3
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| 1 |
IC50 = 11700 nM
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| 2 |
Ki = 6700 nM
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| 3 |
Ki = 13100 nM
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CP0421232
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6-(3,5-dimethylpyrazol-1-yl)-4-N-phenyl-2-N-[(Z)-[(E)-4-phenylbut-3-en-2-ylidene]amino]-1,3,5-triazine-2,4-diamine
Show/Hide
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C24H24N8
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2
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| 1 |
IC50 = 13300 nM
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| 2 |
Ki = 7600 nM
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CP0378611
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-pyridazin-4-ylpyridine-4-carboxamide
Show/Hide
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C24H22N6O3
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2
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| 1 |
IC50 = 15000 nM
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| 2 |
Ki = 39000 nM
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CP0411241
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N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenylpyrazine-2-carboxamide
Show/Hide
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C25H23N5O3
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2
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| 1 |
IC50 > 20000 nM
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| 2 |
Ki = 8500 nM
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CP0421236
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3-(2-methoxyphenyl)-1'-prop-2-enylspiro[1H-quinazoline-2,3'-indole]-2',4-dione
Show/Hide
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C25H21N3O3
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3
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| 1 |
IC50 = 20900 nM
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| 2 |
Ki = 12000 nM
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| 3 |
Ki = 21600 nM
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CP0421238
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methyl 2-[acetyl-[[5-bromo-2-[(2-chlorobenzoyl)amino]phenyl]-phenylmethyl]amino]acetate
Show/Hide
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C25H22BrClN2O4
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2
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| 1 |
IC50 = 53700 nM
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| 2 |
Ki = 30700 nM
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CP0465704
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[3-(2-chloro-6-fluorophenyl)-2-methyl-4-oxochromen-7-yl] (E)-3-(2-methyl-1,3-thiazol-4-yl)prop-2-enoate
Show/Hide
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C23H15ClFNO4S
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1
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| 1 |
IC50 > 100000 nM
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CP0466289
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[(2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrrolidin-1-yl]-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]methanone
Show/Hide
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C27H25N3O4
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1
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| 1 |
IC50 > 100000 nM
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CP0486427
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(5R)-1-(3-chlorophenyl)-5-methyl-4-(naphthalene-1-carbonyl)piperazin-2-one
Show/Hide
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C22H19ClN2O2
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1
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| 1 |
IC50 > 100000 nM
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CP0486430
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4-[[4-(3,5-difluorophenyl)sulfonylpiperazin-1-yl]methyl]-2-(furan-2-yl)-1,3-thiazole
Show/Hide
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C18H17F2N3O3S2
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1
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| 1 |
IC50 > 100000 nM
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CP0486432
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(6aS)-3-[4-(1,3-benzodioxol-5-ylmethyl)piperazine-1-carbonyl]-5,6a,7,8,9,10-hexahydropyrido[1,2-a]quinoxalin-6-one
Show/Hide
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C25H28N4O4
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1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0538101
|
(1-methylindol-3-yl)-[4-(6-methylpyridazin-3-yl)-1,4-diazepan-1-yl]methanone
Show/Hide
|
C20H23N5O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0538111
|
(4R)-1-benzyl-4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]pyrrolidin-2-one
Show/Hide
|
C20H19N3O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0538784
|
3-(2-oxo-3H-benzimidazol-1-yl)propyl 2-methyl-1,3-dioxoisoindole-5-carboxylate
Show/Hide
|
C20H17N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0538785
|
(2-phenyl-1,3-thiazol-5-yl)-[(2S)-2-pyridin-4-ylpyrrolidin-1-yl]methanone
Show/Hide
|
C19H17N3OS
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0551687
|
[2-[(6-methoxynaphthalen-2-yl)methyl-methylamino]-2-oxoethyl] 2,6-difluorobenzoate
Show/Hide
|
C22H19F2NO4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0551688
|
9-methoxy-N-methyl-N-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-7-oxo-3-(1-phenylcyclopropanecarbonyl)-1,2,4,5-tetrahydropyrido[1,2-d][1,4]diazepine-10-carboxamide
Show/Hide
|
C26H29N5O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0552581
|
[(3R)-1-[2-chloro-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]sulfonylpiperidin-3-yl]-(2,3-dihydroindol-1-yl)methanone
Show/Hide
|
C23H23ClN4O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0555800
|
7-[[4-(4,5-dihydrobenzo[g][1]benzothiole-2-carbonyl)piperazin-1-yl]methyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
Show/Hide
|
C24H22N4O2S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0555801
|
N-(1,3-benzothiazol-2-yl)-1-[(3S)-1,1-dioxothiolan-3-yl]-6-oxo-N-(2-phenylethyl)-4,5-dihydropyridazine-3-carboxamide
Show/Hide
|
C24H24N4O4S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0555802
|
(3S)-3-(4-methylphenyl)-3-(4-quinolin-4-yltriazol-1-yl)propan-1-ol
Show/Hide
|
C21H20N4O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0555959
|
[4-(pyridin-2-ylmethyl)piperazin-1-yl]-(3,6,7-trimethyl-1-benzofuran-2-yl)methanone
Show/Hide
|
C22H25N3O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0559973
|
2-[[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazin-1-yl]methyl]-4-(furan-2-yl)-1,3-thiazole
Show/Hide
|
C20H21N3O5S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0559974
|
[2-(1-methyl-2-phenylindol-3-yl)-2-oxoethyl] 9-oxo-2,3-dihydro-1H-pyrrolo[2,1-b]quinazoline-6-carboxylate
Show/Hide
|
C29H23N3O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0561715
|
N-(2,3-dihydro-1H-inden-2-yl)-4-(4-oxo-1,2,3-benzotriazin-3-yl)butanamide
Show/Hide
|
C20H20N4O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0563714
|
1-[3-[(2-fluorophenyl)methoxy]phenyl]-N-(pyridin-2-ylmethyl)methanamine
Show/Hide
|
C20H19FN2O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0565526
|
1-[3-[(2R)-3-acetyl-2-pyridin-3-yl-2H-1,3,4-oxadiazol-5-yl]indol-1-yl]ethanone
Show/Hide
|
C19H16N4O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0565899
|
5-[(E)-(3-methyl-1-phenyl-5-pyrrolidin-1-ylpyrazol-4-yl)methylideneamino]-1-phenylpyrazolo[3,4-d]pyrimidin-4-one
Show/Hide
|
C26H24N8O
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0565900
|
[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-(2,3-dimethyl-1H-indol-5-yl)methanone
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0567399
|
(5E)-1-(1,3-benzodioxol-5-yl)-5-[[2-[(2-fluorophenyl)methoxy]phenyl]methylidene]-1,3-diazinane-2,4,6-trione
Show/Hide
|
C25H17FN2O6
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0567405
|
1-[(3S)-3-benzoylpiperidin-1-yl]-3-[3-(furan-2-yl)-1,2,4-oxadiazol-5-yl]propan-1-one
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0567519
|
4-[3-[(2S)-1-(4-methylphenyl)-1-oxopropan-2-yl]oxyphenyl]-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
Show/Hide
|
C25H23NO4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0570921
|
[(2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrrolidin-1-yl]-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]methanone
Show/Hide
|
C24H24N2O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0574595
|
(2-chloro-5-morpholin-4-ylsulfonylphenyl)-(1,2-dihydroimidazo[1,2-a]benzimidazol-3-yl)methanone
Show/Hide
|
C20H19ClN4O4S
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0575153
|
N-[(1R)-1-(furan-2-yl)ethyl]-9-methoxy-N-methyl-7-oxo-3-(1-phenylcyclopropanecarbonyl)-1,2,4,5-tetrahydropyrido[1,2-d][1,4]diazepine-10-carboxamide
Show/Hide
|
C28H31N3O5
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0576176
|
4-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-oxo-N-[3-(2-pyridin-2-ylethynyl)phenyl]butanamide
Show/Hide
|
C25H20N2O4
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0898626
|
[(2S)-2-(5-methyl-1,2-oxazol-3-yl)piperidin-1-yl]-[4-(1H-pyrazol-5-yl)phenyl]methanone
Show/Hide
|
C19H20N4O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0959442
|
(3S)-3-(2-methyl-1H-indol-3-yl)-2-[3-oxo-3-(4-pyridin-2-ylpiperazin-1-yl)propyl]-3H-isoindol-1-one
Show/Hide
|
C29H29N5O2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0968497
|
2-[(2S)-4-benzylmorpholin-2-yl]-N-methyl-N-[(3-methyl-1H-imidazol-3-ium-2-yl)methyl]acetamide
Show/Hide
|
C19H27N4O2+
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0426710
|
N-[[(2S)-4,4-difluoro-1-(2-methyl-4-phenyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]methyl]quinoline-8-carboxamide
Show/Hide
|
C27H24F2N4O2S
|
1
|
| 1 |
IC50 > 2000 nM
|
|
|
|
CP0269358
|
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-(pyridin-2-ylmethyl)acetamide
Show/Hide
|
C25H22ClN3O3
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0408994
|
2-(1H-indol-3-ylmethyl)-9-pyrimidin-2-yl-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0523659
|
2-(1H-indol-3-ylmethyl)-9-pyrazin-2-yl-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C22H25N5O
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0505828
|
4-fluoro-N-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C26H25FN2O2
|
1
|
| 1 |
Ki = 0.1259 nM
|
|
|
|
CP0521843
|
[(2S)-2-[2-(2,4-difluorophenoxy)ethyl]piperidin-1-yl]-(2-phenylphenyl)methanone
Show/Hide
|
C26H25F2NO2
|
1
|
| 1 |
Ki = 0.1585 nM
|
|
|
|
CP0087270
|
SB-649868
Show/Hide
|
C26H24FN3O3S
|
2
|
| 1 |
Ki = 0.3162 nM
|
|
|
| 2 |
Ki = 0.7586 nM
|
|
|
|
CP0422093
|
(2S)-1-[2-(1,5-dimethylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H27N5O2S
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0527425
|
US9029364, 1
Show/Hide
|
C21H22FN5O2S
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
|
CP0390193
|
1-phenyl-3-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]urea
Show/Hide
|
C26H27N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0404095
|
(1R,2S)-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)-2-[[4-(methoxymethyl)-2-methylpyrimidin-5-yl]oxymethyl]cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0515983
|
(2S)-1-[2-(1,6-dimethylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H27N5O2S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0059177
|
(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C27H26N4O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0391199
|
(2S)-1-[2-[(6-methyl-1H-benzimidazol-2-yl)sulfanyl]acetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C25H25N5O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0467638
|
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-N-(5-fluoro-4-methoxypyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0064572
|
[5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]-[(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
|
C24H21FN4O2S
|
1
|
| 1 |
Ki = 3.89 nM
|
|
|
|
CP0482122
|
[2-[2-(4-fluorophenoxy)ethyl]piperidin-1-yl]-(2-phenylphenyl)methanone
Show/Hide
|
C26H26FNO2
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0462719
|
US9029364, 5
Show/Hide
|
C20H20ClN5O2S
|
1
|
| 1 |
Ki = 5.8 nM
|
|
|
|
CP0520782
|
[(2S)-2-[2-(4-fluorophenoxy)ethyl]piperidin-1-yl]-naphthalen-1-ylmethanone
Show/Hide
|
C24H24FNO2
|
1
|
| 1 |
Ki = 6.31 nM
|
|
|
|
CP0411781
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N,2-diphenylcyclopropane-1-carboxamide
Show/Hide
|
C25H25NO4
|
1
|
| 1 |
Ki = 7.2 nM
|
|
|
|
CP0385077
|
US9029364, 3
Show/Hide
|
C20H20FN5O2S
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0458767
|
N-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
Ki = 7.943 nM
|
|
|
|
CP0223432
|
US8680275, 4
Show/Hide
|
C25H22N4OS
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0564035
|
US8680275, 5
Show/Hide
|
C25H22N4O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0436316
|
(2S)-1-[2-(1-methylbenzimidazol-2-yl)sulfanylacetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C25H25N5O2S
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0411322
|
(1R,2S)-N-(5-fluoropyridin-2-yl)-2-[[4-(methoxymethyl)-2-methylpyrimidin-5-yl]oxymethyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H23FN4O3
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0158173
|
US8530648, 75
Show/Hide
|
C26H27N5O
|
1
|
| 1 |
Ki = 9.12 nM
|
|
|
|
CP0382196
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O2S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0474851
|
1-phenyl-3-[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]propan-1-one
Show/Hide
|
C27H27NO2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0404057
|
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-N-(5-fluoro-6-methoxypyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0043150
|
US8680275, 196
Show/Hide
|
C25H22F4N4O2
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0394570
|
(2S)-1-[3-(1-methylbenzimidazol-2-yl)propanoyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C28H28N4O2
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0158234
|
US8680275, 195
Show/Hide
|
C25H23F3N4O
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0099532
|
US8680275, 10
Show/Hide
|
C28H26N4O
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0108164
|
US8530648, 94
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
Ki = 18.62 nM
|
|
|
|
CP0408991
|
9-(4,6-dimethylpyrimidin-2-yl)-2-[(5-methoxy-1H-indol-3-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C25H31N5O2
|
1
|
| 1 |
Ki = 20.42 nM
|
|
|
|
CP0286242
|
US8680275, 9
Show/Hide
|
C29H26N4O
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0086146
|
US8680275, 116
Show/Hide
|
C23H20FN7O
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0510196
|
US8680275, 117
Show/Hide
|
C23H20FN7O
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0545696
|
US9029364, 4
Show/Hide
|
C21H23N5O2S
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0382195
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-[2-(2-fluorophenyl)phenyl]pyrrolidine-2-carboxamide
Show/Hide
|
C27H25FN4O2
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0433114
|
(S)-1-(2-(1H-benzo[d]imidazol-2-ylthio)acetyl)-N-(2-(1H-pyrrol-1-yl)phenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H23N5O2S
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0513079
|
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluoro-4-methoxyphenyl)-N-(5-fluoropyridin-2-yl)cyclopropane-1-carboxamide
Show/Hide
|
C23H22F2N4O3
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0395789
|
(1R,2S)-N-(5-cyanopyridin-2-yl)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluorophenyl)cyclopropane-1-carboxamide
Show/Hide
|
C23H20FN5O2
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0471181
|
US8680275, 119
Show/Hide
|
C22H19ClN6O2
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0510191
|
US8680275, 39
Show/Hide
|
C23H21N7O
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0457270
|
[5-fluoro-2-(triazol-2-yl)phenyl]-[(1R,6S)-8-quinoxalin-2-yl-3,8-diazabicyclo[4.2.0]octan-3-yl]methanone
Show/Hide
|
C23H20FN7O
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0433116
|
(2S)-1-[2-(1,3-benzothiazol-2-ylsulfanyl)acetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H22N4O2S2
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0235016
|
US8680275, 50
Show/Hide
|
C26H22N4OS
|
1
|
| 1 |
Ki = 39 nM
|
|
|
|
CP0474850
|
4-fluoro-N-[[(2R)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C26H25FN2O2
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0382190
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-(2-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C27H26N4O2
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0575132
|
1-(2-amino-1,3-benzoxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea
Show/Hide
|
C16H12N6O2
|
1
|
| 1 |
Ki = 41.69 nM
|
|
|
|
CP0563353
|
US8680275, 120
Show/Hide
|
C22H18ClFN6O2
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0204132
|
US8680275, 24
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
Ki = 44 nM
|
|
|
|
CP0099342
|
US8680275, 46
Show/Hide
|
C22H22F4N8O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0510189
|
US8680275, 33
Show/Hide
|
C25H21FN6O
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0405058
|
(2S)-1-[3-(1-methylbenzimidazol-2-yl)propanoyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H27N5O2
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0499127
|
N-phenyl-2-[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]acetamide
Show/Hide
|
C26H26N2O2
|
1
|
| 1 |
Ki = 50.12 nM
|
|
|
|
CP0363304
|
US8680275, 26
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0504443
|
2-{(5S)-5-Methyl-4-[2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}quinazoline
Show/Hide
|
C23H23N7O
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0407070
|
US9029364, 2
Show/Hide
|
C20H21N5O2S
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0212327
|
US8680275, 56
Show/Hide
|
C26H22N4OS
|
1
|
| 1 |
Ki = 55 nM
|
|
|
|
CP0058849
|
US8530648, 85
Show/Hide
|
C26H30N4O
|
1
|
| 1 |
Ki = 58.88 nM
|
|
|
|
CP0507162
|
US8680275, 2
Show/Hide
|
C23H24N4O2
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0529034
|
US8680275, 1
Show/Hide
|
C23H24N4OS
|
1
|
| 1 |
Ki = 64 nM
|
|
|
|
CP0382194
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(2-phenoxyphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O3S
|
1
|
| 1 |
Ki = 69 nM
|
|
|
|
CP0415631
|
US9029364, 8
Show/Hide
|
C20H20ClN5O2S
|
1
|
| 1 |
Ki = 75.7 nM
|
|
|
|
CP0170502
|
US8680275, 38
Show/Hide
|
C22H22F4N8O
|
1
|
| 1 |
Ki = 77 nM
|
|
|
|
CP0471179
|
US8680275, 13
Show/Hide
|
C21H19BrN4O
|
1
|
| 1 |
Ki = 78 nM
|
|
|
|
CP0394568
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-[2-(2-methoxyphenyl)phenyl]pyrrolidine-2-carboxamide
Show/Hide
|
C28H28N4O3
|
1
|
| 1 |
Ki = 86 nM
|
|
|
|
CP0226935
|
US8680275, 121
Show/Hide
|
C22H18ClFN6O2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0060119
|
US8680275, 123
Show/Hide
|
C22H18ClFN6O2
|
1
|
| 1 |
Ki = 95 nM
|
|
|
|
CP0222135
|
US8680275, 14
Show/Hide
|
C26H23N5O
|
1
|
| 1 |
Ki = 96 nM
|
|
|
|
CP0544771
|
US9029364, 12
Show/Hide
|
C20H21ClN6O2S
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0414115
|
(1R,2S)-N-(4-cyanopyridin-2-yl)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C25H23N3O4
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0338629
|
US8680275, 52
Show/Hide
|
C26H22FN5OS
|
1
|
| 1 |
Ki = 104 nM
|
|
|
|
CP0414117
|
[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-(6-fluoro-1H-benzimidazol-2-yl)methanone
Show/Hide
|
C26H23FN2O4
|
1
|
| 1 |
Ki = 106 nM
|
|
|
|
CP0474548
|
US9029364, 10
Show/Hide
|
C21H23N5O2S
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0213177
|
US8680275, 49
Show/Hide
|
C24H20N4OS
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0510190
|
US8680275, 35
Show/Hide
|
C21H20F3N7O
|
1
|
| 1 |
Ki = 117 nM
|
|
|
|
CP0382191
|
(2S)-1-[2-(1,3-benzoxazol-2-ylsulfanyl)acetyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H22N4O3S
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0543529
|
US9029364, 7
Show/Hide
|
C21H20F3N5O2S
|
1
|
| 1 |
Ki = 121 nM
|
|
|
|
CP0199037
|
(1R,2S)-N-(5-cyanopyridin-2-yl)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C25H23N3O4
|
1
|
| 1 |
Ki = 123 nM
|
|
|
|
CP0482124
|
[2-[2-(3,4-dichlorophenoxy)ethyl]piperidin-1-yl]-(3-methoxyphenyl)methanone
Show/Hide
|
C21H23Cl2NO3
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0510197
|
US8680275, 122
Show/Hide
|
C22H18ClFN6O2
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0557756
|
US8680275, 69
Show/Hide
|
C25H23N7O
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0382193
|
(2S)-1-[3-(1H-benzimidazol-2-yl)propanoyl]-N-(2-pyrrol-1-ylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C25H25N5O2
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0366527
|
US8680275, 32
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 134 nM
|
|
|
|
CP0363356
|
US8680275, 135
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 135 nM
|
|
|
|
CP0380127
|
N-[2-[3-[[5-[3-(dimethylcarbamoyl)phenyl]-2-methoxyphenyl]sulfonylamino]anilino]ethyl]-3-methylbenzamide
Show/Hide
|
C32H34N4O5S
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0072880
|
US8680275, 27
Show/Hide
|
C24H26N6O
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0257686
|
US8680275, 11
Show/Hide
|
C26H23N3O2
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0113002
|
US8680275, 184
Show/Hide
|
C22H23FN6O
|
1
|
| 1 |
Ki = 156 nM
|
|
|
|
CP0519161
|
US8680275, 115
Show/Hide
|
C23H20FN7O
|
1
|
| 1 |
Ki = 177 nM
|
|
|
|
CP0544205
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenyl-N-pyridin-3-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 206 nM
|
|
|
|
CP0554498
|
US8680275, 47
Show/Hide
|
C28H24N4O
|
1
|
| 1 |
Ki = 206 nM
|
|
|
|
CP0296027
|
[4-(6-chloro-1,3-benzothiazol-2-yl)-1,4-diazepan-1-yl]-(2,6-dimethoxyphenyl)methanone
Show/Hide
|
C21H22ClN3O3S
|
1
|
| 1 |
Ki = 216 nM
|
|
|
|
CP0226938
|
US8680275, 167
Show/Hide
|
C26H26N4O
|
1
|
| 1 |
Ki = 219 nM
|
|
|
|
CP0098523
|
US8680275, 92
Show/Hide
|
C23H20F4N6O
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0144527
|
US8680275, 67
Show/Hide
|
C24H21N7O
|
1
|
| 1 |
Ki = 225 nM
|
|
|
|
CP0507163
|
US8680275, 15
Show/Hide
|
C25H26N4O3
|
1
|
| 1 |
Ki = 237 nM
|
|
|
|
CP0465546
|
US8680275, 19
Show/Hide
|
C24H26N4O2S
|
1
|
| 1 |
Ki = 254 nM
|
|
|
|
CP0120862
|
US8680275, 48
Show/Hide
|
C26H22N4O
|
1
|
| 1 |
Ki = 258 nM
|
|
|
|
CP0544419
|
US9029364, 16
Show/Hide
|
C20H20FN5O4S
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0366457
|
US8680275, 129
Show/Hide
|
C21H18F4N6O
|
1
|
| 1 |
Ki = 265 nM
|
|
|
|
CP0510192
|
US8680275, 55
Show/Hide
|
C26H22N4OS
|
1
|
| 1 |
Ki = 274 nM
|
|
|
|
CP0072739
|
US8530648, 97
Show/Hide
|
C26H27N5O
|
1
|
| 1 |
Ki = 275.42 nM
|
|
|
|
CP0510198
|
US8680275, 134
Show/Hide
|
C22H25N7O2
|
1
|
| 1 |
Ki = 277 nM
|
|
|
|
CP0065658
|
US8530648, 28
Show/Hide
|
C26H27N5O
|
1
|
| 1 |
Ki = 288.4 nM
|
|
|
|
CP0418621
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-(5-methyl-1,3-thiazol-2-yl)-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H24N2O4S
|
1
|
| 1 |
Ki = 291 nM
|
|
|
|
CP0106825
|
US8680275, 29
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 325 nM
|
|
|
|
CP0176361
|
US8680275, 28
Show/Hide
|
C23H24N6O
|
1
|
| 1 |
Ki = 330 nM
|
|
|
|
CP0355320
|
US8680275, 151
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
Ki = 341 nM
|
|
|
|
CP0542116
|
US9029364, 6
Show/Hide
|
C21H20N6O2S
|
1
|
| 1 |
Ki = 346 nM
|
|
|
|
CP0279196
|
US8680275, 7
Show/Hide
|
C23H25N5O
|
1
|
| 1 |
Ki = 371 nM
|
|
|
|
CP0540425
|
9-(4,6-dimethylpyrimidin-2-yl)-1-(1H-indol-4-ylmethyl)-1,9-diazaspiro[5.5]undecan-2-one
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
Ki = 371.54 nM
|
|
|
|
CP0234820
|
US8680275, 20
Show/Hide
|
C23H24N4O
|
1
|
| 1 |
Ki = 379 nM
|
|
|
|
CP0086159
|
US8680275, 171
Show/Hide
|
C22H23FN6O
|
1
|
| 1 |
Ki = 392 nM
|
|
|
|
CP0456216
|
3-[2-[2-(3,4-dichlorophenoxy)ethyl]piperidine-1-carbonyl]benzonitrile
Show/Hide
|
C21H20Cl2N2O2
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0336902
|
US8680275, 42
Show/Hide
|
C21H19F4N7O
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0265420
|
US8680275, 25
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 416 nM
|
|
|
|
CP0563352
|
US8680275, 51
Show/Hide
|
C24H20FN5OS
|
1
|
| 1 |
Ki = 432 nM
|
|
|
|
CP0231759
|
US8680275, 41
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 441 nM
|
|
|
|
CP0507164
|
US8680275, 16
Show/Hide
|
C22H23N3O4
|
1
|
| 1 |
Ki = 460 nM
|
|
|
|
CP0368688
|
US8680275, 22
Show/Hide
|
C23H23FN6O
|
1
|
| 1 |
Ki = 473 nM
|
|
|
|
CP0109955
|
US8680275, 43
Show/Hide
|
C22H26N8O
|
1
|
| 1 |
Ki = 475 nM
|
|
|
|
CP0565281
|
US8680275, 44
Show/Hide
|
C22H25FN8O
|
1
|
| 1 |
Ki = 480 nM
|
|
|
|
CP0390786
|
9-(4,6-dimethylpyrimidin-2-yl)-2-(2H-indazol-3-ylmethyl)-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C23H28N6O
|
1
|
| 1 |
Ki = 489.78 nM
|
|
|
|
CP0501979
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(3-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O2S
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0512555
|
4-fluoro-N-methyl-N-[[(2S)-1-(2-phenylbenzoyl)piperidin-2-yl]methyl]benzamide
Show/Hide
|
C27H27FN2O2
|
1
|
| 1 |
Ki = 501.19 nM
|
|
|
|
CP0413168
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-(5-methyl-1,2-oxazol-3-yl)-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H24N2O5
|
1
|
| 1 |
Ki = 505 nM
|
|
|
|
CP0404060
|
2-(1H-indol-3-ylmethyl)-9-(4-methoxypyrimidin-2-yl)-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C23H27N5O2
|
1
|
| 1 |
Ki = 512.86 nM
|
|
|
|
CP0170557
|
2-(1H-indol-4-ylmethyl)-9-quinoxalin-2-yl-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C26H27N5O
|
1
|
| 1 |
Ki = 549.54 nM
|
|
|
|
CP0342991
|
US8680275, 133
Show/Hide
|
C23H26N6O
|
1
|
| 1 |
Ki = 550 nM
|
|
|
|
CP0342975
|
US8680275, 185
Show/Hide
|
C23H23FN6O
|
1
|
| 1 |
Ki = 600 nM
|
|
|
|
CP0133712
|
US8680275, 23
Show/Hide
|
C23H23FN6O
|
1
|
| 1 |
Ki = 619 nM
|
|
|
|
CP0565282
|
US8680275, 95
Show/Hide
|
C20H17F4N7O
|
1
|
| 1 |
Ki = 625 nM
|
|
|
|
CP0508125
|
N-(3,4-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki = 630.96 nM
|
|
|
|
CP0148843
|
US8680275, 12
Show/Hide
|
C23H24N4O3
|
1
|
| 1 |
Ki = 659 nM
|
|
|
|
CP0408993
|
9-(4,6-dimethylpyrimidin-2-yl)-2-(1H-indol-3-ylmethyl)-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
Ki = 660.69 nM
|
|
|
|
CP0230076
|
US8680275, 153
Show/Hide
|
C24H24FN5O
|
1
|
| 1 |
Ki = 687 nM
|
|
|
|
CP0108708
|
US8680275, 45
Show/Hide
|
C22H25FN8O
|
1
|
| 1 |
Ki = 697 nM
|
|
|
|
CP0411651
|
9-(4,6-dimethylpyrimidin-2-yl)-2-[(5-phenyl-2H-triazol-4-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C24H29N7O
|
1
|
| 1 |
Ki = 707.95 nM
|
|
|
|
CP0400056
|
(1R,2S)-2-[[4-methoxy-3-(methoxymethyl)phenoxy]methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C25H26N2O4
|
1
|
| 1 |
Ki = 747 nM
|
|
|
|
CP0408989
|
9-(4,6-dimethylpyrimidin-2-yl)-2-[(2-methyl-5-phenyltriazol-4-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C25H31N7O
|
1
|
| 1 |
Ki = 758.58 nM
|
|
|
|
CP0387709
|
(1R,2S)-2-[[3-methoxy-4-(methoxymethyl)phenoxy]methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C25H26N2O4
|
1
|
| 1 |
Ki = 772 nM
|
|
|
|
CP0479739
|
9-(4,6-dimethylpyrimidin-2-yl)-2-[(4-phenyl-1H-pyrazol-5-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C25H30N6O
|
1
|
| 1 |
Ki = 776.25 nM
|
|
|
|
CP0564039
|
US8680275, 147
Show/Hide
|
C22H21F3N6O
|
1
|
| 1 |
Ki = 793 nM
|
|
|
|
CP0262389
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0489665
|
N-[4-(dimethylamino)phenyl]-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H23N5O3S
|
1
|
| 1 |
Ki = 794.33 nM
|
|
|
|
CP0510193
|
US8680275, 64
Show/Hide
|
C24H26N4O4
|
1
|
| 1 |
Ki = 808 nM
|
|
|
|
CP0531898
|
9-(4,6-dimethylpyrimidin-2-yl)-2-[(1-methyl-4-phenylpyrazol-3-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C26H32N6O
|
1
|
| 1 |
Ki = 812.83 nM
|
|
|
|
CP0400057
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-(4-methyl-1,3-thiazol-2-yl)-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C23H24N2O4S
|
1
|
| 1 |
Ki = 832 nM
|
|
|
|
CP0226918
|
US8680275, 148
Show/Hide
|
C22H23FN6O
|
1
|
| 1 |
Ki = 845 nM
|
|
|
|
CP0213130
|
US8680275, 156
Show/Hide
|
C24H25FN6O2
|
1
|
| 1 |
Ki = 860 nM
|
|
|
|
CP0408988
|
2-phenyl-1-(8-quinoxalin-2-yl-1,8-diazaspiro[4.5]decan-1-yl)ethanone
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 954.99 nM
|
|
|
|
CP0507165
|
US8680275, 30
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 978 nM
|
|
|
|
CP0527228
|
N-(3-chloro-4-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H16ClFN4O3S
|
1
|
| 1 |
Ki = 1000 nM
|
|
|
|
CP0330162
|
US8680275, 128
Show/Hide
|
C22H23FN6O
|
1
|
| 1 |
Ki = 1013 nM
|
|
|
|
CP0560816
|
US8680275, 34
Show/Hide
|
C21H19F4N7O
|
1
|
| 1 |
Ki = 1043 nM
|
|
|
|
CP0428213
|
US8680275, 65
Show/Hide
|
C24H26N4O2
|
1
|
| 1 |
Ki = 1066 nM
|
|
|
|
CP0400055
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 1068 nM
|
|
|
|
CP0535969
|
US8680275, 140
Show/Hide
|
C22H21F3N6O2
|
1
|
| 1 |
Ki = 1072 nM
|
|
|
|
CP0481486
|
US9029364, 13
Show/Hide
|
C20H21ClN6O2S
|
1
|
| 1 |
Ki = 1119 nM
|
|
|
|
CP0363333
|
US8680275, 154
Show/Hide
|
C20H22BrFN4O2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0212290
|
US8680275, 21
Show/Hide
|
C22H24N4O2S
|
1
|
| 1 |
Ki = 1208 nM
|
|
|
|
CP0247428
|
US8680275, 40
Show/Hide
|
C22H25FN8O
|
1
|
| 1 |
Ki = 1210 nM
|
|
|
|
CP0518388
|
US8680275, 172
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 1249 nM
|
|
|
|
CP0523671
|
N-(2,4-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0555808
|
7-fluoro-2,3-dimethyl-N-(2-naphthalen-2-yloxyethyl)quinoxaline-5-carboxamide
Show/Hide
|
C23H20FN3O2
|
1
|
| 1 |
Ki = 1258.93 nM
|
|
|
|
CP0567298
|
US8680275, 188
Show/Hide
|
C23H25FN6O
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0479738
|
9-(4,6-dimethylpyrimidin-2-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C23H28N6O
|
1
|
| 1 |
Ki = 1318.26 nM
|
|
|
|
CP0064578
|
1-(2,4-dibromophenyl)-3-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]urea
Show/Hide
|
C19H20Br2N2O3
|
1
|
| 1 |
Ki = 1348.96 nM
|
|
|
|
CP0462533
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-phenylpyrrolidine-2-carboxamide
Show/Hide
|
C20H20N4O2S
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0422531
|
US9029364, 15
Show/Hide
|
C20H20FN5O3S
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0404061
|
2-(1H-indol-3-ylmethyl)-9-(4-methylpyrimidin-2-yl)-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C23H27N5O
|
1
|
| 1 |
Ki = 1412.54 nM
|
|
|
|
CP0387710
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenyl-N-pyridin-4-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 1425 nM
|
|
|
|
CP0523660
|
9-(4,6-dimethylpyrimidin-2-yl)-2-[(1-methylindol-3-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
Show/Hide
|
C25H31N5O
|
1
|
| 1 |
Ki = 1445.44 nM
|
|
|
|
CP0137146
|
US8530648, 200
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 1479.11 nM
|
|
|
|
CP0234830
|
US8680275, 155
Show/Hide
|
C22H23FN6O
|
1
|
| 1 |
Ki = 1530 nM
|
|
|
|
CP0169008
|
US8530648, 6
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
Ki = 1548.82 nM
|
|
|
|
CP0128556
|
5-(5-chloropyridin-3-yl)-N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-pyridin-2-ylpyridine-3-carboxamide
Show/Hide
|
C24H20ClN5O3
|
1
|
| 1 |
Ki = 1584 nM
|
|
|
|
CP0223453
|
US8680275, 169
Show/Hide
|
C22H24N6O2
|
1
|
| 1 |
Ki = 1589 nM
|
|
|
|
CP0148883
|
US8680275, 131
Show/Hide
|
C21H21FN6O
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0486059
|
US8680275, 138
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
Ki = 1649 nM
|
|
|
|
CP0125290
|
US8680275, 130
Show/Hide
|
C21H18F4N6O
|
1
|
| 1 |
Ki = 1715 nM
|
|
|
|
CP0350638
|
US8680275, 152
Show/Hide
|
C23H19F4N5O
|
1
|
| 1 |
Ki = 1852 nM
|
|
|
|
CP0553893
|
US8680275, 112
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 1960 nM
|
|
|
|
CP0386670
|
N-(3-chlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17ClN4O3S
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0493788
|
N-(4-chlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17ClN4O3S
|
1
|
| 1 |
Ki = 1995.26 nM
|
|
|
|
CP0515137
|
US8680275, 173
Show/Hide
|
C24H27N5OS
|
1
|
| 1 |
Ki = 2149 nM
|
|
|
|
CP0458985
|
US9029364, 17
Show/Hide
|
C20H21N5OS2
|
1
|
| 1 |
Ki = 2253 nM
|
|
|
|
CP0433115
|
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(4-phenylphenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C26H24N4O2S
|
1
|
| 1 |
Ki = 2300 nM
|
|
|
|
CP0399525
|
N-[(5,6-dimethoxypyridin-2-yl)methyl]-6-(5-methylpyridin-3-yl)-3-phenylpyridine-2-carboxamide
Show/Hide
|
C26H24N4O3
|
1
|
| 1 |
Ki = 2400 nM
|
|
|
|
CP0087010
|
US8680275, 177
Show/Hide
|
C22H22FN5O2
|
1
|
| 1 |
Ki = 2400 nM
|
|
|
|
CP0382197
|
(R)-1-(2-(1H-benzo[d]imidazol-2-ylthio)acetyl)-N-(2-(1H-pyrrol-1-yl)phenyl)pyrrolidine-2-carboxamide
Show/Hide
|
C24H23N5O2S
|
1
|
| 1 |
Ki = 2500 nM
|
|
|
|
CP0389412
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxy-5-methylphenyl)acetamide
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0489661
|
N-(4-acetylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H20N4O4S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0489666
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(3-methylphenyl)acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0390190
|
[2-[2-(3,4-dichlorophenoxy)ethyl]piperidin-1-yl]-(3,4-dichlorophenyl)methanone
Show/Hide
|
C20H19Cl4NO2
|
1
|
| 1 |
Ki = 2511.89 nM
|
|
|
|
CP0204062
|
US8680275, 197
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
Ki = 2600 nM
|
|
|
|
CP0386590
|
(1R,2S)-N-cyclohexyl-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropane-1-carboxamide
Show/Hide
|
C25H31NO4
|
1
|
| 1 |
Ki = 2994 nM
|
|
|
|
CP0489664
|
N-(3-acetylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H20N4O4S
|
1
|
| 1 |
Ki = 3162.28 nM
|
|
|
|
CP0450532
|
US8680275, 158
Show/Hide
|
C22H26N8O
|
1
|
| 1 |
Ki = 3200 nM
|
|
|
|
CP0486429
|
2-[2-(3-fluorophenyl)-1,3-thiazol-4-yl]-N-methyl-N-[(2-methylphenyl)methyl]acetamide
Show/Hide
|
C20H19FN2OS
|
1
|
| 1 |
Ki = 3235.94 nM
|
|
|
|
CP0471182
|
US8680275, 125
Show/Hide
|
C21H22N6O
|
1
|
| 1 |
Ki = 3298 nM
|
|
|
|
CP0064978
|
US8680275, 145
Show/Hide
|
C21H18F4N6O
|
1
|
| 1 |
Ki = 3299 nM
|
|
|
|
CP0560817
|
US8680275, 54
Show/Hide
|
C21H20N4O2
|
1
|
| 1 |
Ki = 3447 nM
|
|
|
|
CP0371503
|
US8680275, 104
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 3536 nM
|
|
|
|
CP0486431
|
5-(1,3-benzothiazol-2-yl)-N,N-bis(furan-2-ylmethyl)furan-2-carboxamide
Show/Hide
|
C22H16N2O4S
|
1
|
| 1 |
Ki = 3548.13 nM
|
|
|
|
CP0133814
|
US8680275, 57
Show/Hide
|
C22H22N4OS
|
1
|
| 1 |
Ki = 3566 nM
|
|
|
|
CP0256542
|
US8680275, 93
Show/Hide
|
C20H19F3N8O
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0116104
|
US8680275, 53
Show/Hide
|
C23H22N4O2
|
1
|
| 1 |
Ki = 3703 nM
|
|
|
|
CP0121043
|
US8680275, 166
Show/Hide
|
C26H29FN6O
|
1
|
| 1 |
Ki = 3841 nM
|
|
|
|
CP0203967
|
US8680275, 157
Show/Hide
|
C22H26N8O
|
1
|
| 1 |
Ki = 3900 nM
|
|
|
|
CP0556853
|
US8680275, 164
Show/Hide
|
C19H20BrFN4O
|
1
|
| 1 |
Ki = 3900 nM
|
|
|
|
CP0531666
|
US8680275, 189
Show/Hide
|
C21H23FN8O
|
1
|
| 1 |
Ki = 4100 nM
|
|
|
|
CP0550291
|
US8680275, 99
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 4135 nM
|
|
|
|
CP0279188
|
US8680275, 124
Show/Hide
|
C21H21FN6O
|
1
|
| 1 |
Ki = 4148 nM
|
|
|
|
CP0414240
|
N-[[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]methyl]aniline
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
Ki = 4161 nM
|
|
|
|
CP0086435
|
N-ethyl-2-[(6-methoxypyridin-3-yl)-(2-methylphenyl)sulfonylamino]-N-(pyridin-3-ylmethyl)acetamide
Show/Hide
|
C23H26N4O4S
|
1
|
| 1 |
Ki = 4466.84 nM
|
|
|
|
CP0099507
|
US8680275, 161
Show/Hide
|
C21H24N8O
|
1
|
| 1 |
Ki = 4500 nM
|
|
|
|
CP0126923
|
US8680275, 98
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 4916 nM
|
|
|
|
CP0043083
|
US8680275, 68
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0223575
|
US8680275, 62
Show/Hide
|
C21H20N4O2S
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0335954
|
US8680275, 111
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 5000 nM
|
|
|
|
CP0120655
|
US8680275, 97
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
Ki = 5019 nM
|
|
|
|
CP0561093
|
N-[2-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]pyridin-3-yl]-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide
Show/Hide
|
C25H24N2O4
|
1
|
| 1 |
Ki = 5128.61 nM
|
|
|
|
CP0571762
|
3-[(2R)-1-oxo-1-phenylpropan-2-yl]oxybenzo[c]chromen-6-one
Show/Hide
|
C22H16O4
|
1
|
| 1 |
Ki = 5370.32 nM
|
|
|
|
CP0199618
|
US8680275, 126
Show/Hide
|
C21H21FN6O
|
1
|
| 1 |
Ki = 5468 nM
|
|
|
|
CP0398519
|
(1R,2S)-2-[(4-methoxyphenoxy)methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C23H22N2O3
|
1
|
| 1 |
Ki = 5538 nM
|
|
|
|
CP0230095
|
US8680275, 96
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
Ki = 5843 nM
|
|
|
|
CP0170418
|
US8680275, 160
Show/Hide
|
C21H24N8O
|
1
|
| 1 |
Ki = 5999 nM
|
|
|
|
CP0327272
|
US8680275, 139
Show/Hide
|
C22H24N6O2
|
1
|
| 1 |
Ki = 6500 nM
|
|
|
|
CP0483605
|
US8680275, 101
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 6599 nM
|
|
|
|
CP0398234
|
(1R,2S)-2-(phenoxymethyl)-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C22H20N2O2
|
1
|
| 1 |
Ki = 6841 nM
|
|
|
|
CP0479322
|
US8680275, 178
Show/Hide
|
C22H22ClN5O2
|
1
|
| 1 |
Ki = 7000 nM
|
|
|
|
CP0223445
|
US8680275, 168
Show/Hide
|
C26H24N4O2
|
1
|
| 1 |
Ki = 7300 nM
|
|
|
|
CP0387588
|
(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-N-methyl-N,2-diphenylcyclopropane-1-carboxamide
Show/Hide
|
C26H27NO4
|
1
|
| 1 |
Ki = 7535 nM
|
|
|
|
CP0486428
|
(3aS,4R,7aS)-4-methyl-2-[3-[(2S)-1-(4-methylphenyl)-1-oxopropan-2-yl]oxyphenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione
Show/Hide
|
C25H25NO4
|
1
|
| 1 |
Ki = 7762.47 nM
|
|
|
|
CP0465678
|
3-(phenoxymethyl)-N-[3-[(E)-2-pyridin-2-ylethenyl]phenyl]furan-2-carboxamide
Show/Hide
|
C25H20N2O3
|
1
|
| 1 |
Ki = 7943.28 nM
|
|
|
|
CP0231775
|
US8680275, 88
Show/Hide
|
C21H24N8O
|
1
|
| 1 |
Ki = 8200 nM
|
|
|
|
CP0257440
|
US8680275, 100
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 8700 nM
|
|
|
|
CP0465681
|
(2S)-1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[2-(furan-2-yl)quinazolin-4-yl]sulfanylpropan-1-one
Show/Hide
|
C24H21N3O2S
|
1
|
| 1 |
Ki = 8912.51 nM
|
|
|
|
CP0041052
|
US8680275, 146
Show/Hide
|
C22H21F3N6O2
|
1
|
| 1 |
Ki = 8999 nM
|
|
|
|
CP0043880
|
US8680275, 113
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 8999 nM
|
|
|
|
CP0170663
|
US8680275, 141
Show/Hide
|
C23H27N7O
|
1
|
| 1 |
Ki = 8999 nM
|
|
|
|
CP0122060
|
US8680275, 58
Show/Hide
|
C18H19BrN4O
|
1
|
| 1 |
Ki = 9654 nM
|
|
|
|
CP0226930
|
US8680275, 66
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 9654 nM
|
|
|
|
CP0379310
|
(1R,2S)-2-(3,4-dimethoxyphenyl)-2-(phenoxymethyl)-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0387616
|
1-[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-2-phenylethanone
Show/Hide
|
C26H26O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0400054
|
3,4-dihydro-2H-quinolin-1-yl-[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]methanone
Show/Hide
|
C28H29NO4
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0400058
|
(1R,2S)-2-[(3-methoxyphenoxy)methyl]-2-phenyl-N-pyridin-2-ylcyclopropane-1-carboxamide
Show/Hide
|
C23H22N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0494472
|
[(1R,2S)-2-[(3,4-dimethoxyphenoxy)methyl]-2-phenylcyclopropyl]-phenylmethanone
Show/Hide
|
C25H24O4
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0060141
|
US8680275, 105
Show/Hide
|
C20H21N7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0064772
|
US8680275, 60
Show/Hide
|
C21H20N4OS
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0065572
|
US8680275, 144
Show/Hide
|
C22H24FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0072879
|
US8680275, 176
Show/Hide
|
C22H23N5O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0108672
|
US8680275, 127
Show/Hide
|
C21H21FN6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0116295
|
US8680275, 132
Show/Hide
|
C21H22N6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0126924
|
US8680275, 190
Show/Hide
|
C20H21FN8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0128364
|
US8680275, 194
Show/Hide
|
C22H23FN8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0132994
|
US8680275, 87
Show/Hide
|
C20H18ClFN6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0133187
|
US8680275, 102
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0133293
|
US8680275, 149
Show/Hide
|
C23H26N6O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0148655
|
US8680275, 143
Show/Hide
|
C24H25FN6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0158255
|
US8680275, 63
Show/Hide
|
C23H22N4O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0170451
|
US8680275, 137
Show/Hide
|
C23H24N6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0170547
|
US8680275, 180
Show/Hide
|
C20H23N7O2S
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0204040
|
US8680275, 191
Show/Hide
|
C20H21FN8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0212418
|
US8680275, 192
Show/Hide
|
C19H20FN9O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0223597
|
US8680275, 114
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0224192
|
US8680275, 175
Show/Hide
|
C23H25N5O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0227083
|
US8680275, 108
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0231764
|
US8680275, 187
Show/Hide
|
C21H23FN8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0234793
|
US8680275, 61
Show/Hide
|
C23H22N4O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0321622
|
US8680275, 174
Show/Hide
|
C22H24N6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0338560
|
US8680275, 193
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0350527
|
US8680275, 136
Show/Hide
|
C19H24N6O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0350605
|
US8680275, 110
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0351596
|
US8680275, 142
Show/Hide
|
C23H27N7O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0363838
|
US8680275, 150
Show/Hide
|
C23H27N7O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0364985
|
US8680275, 165
Show/Hide
|
C23H23FN6O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0369780
|
US8680275, 59
Show/Hide
|
C17H17BrN4O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0471186
|
US8680275, 159
Show/Hide
|
C21H21F3N8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0471187
|
US8680275, 183
Show/Hide
|
C20H22N8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0484924
|
US8680275, 94
Show/Hide
|
C20H17F4N7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0484925
|
US8680275, 182
Show/Hide
|
C20H22N8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0507166
|
US8680275, 179
Show/Hide
|
C21H24N6O3
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0507167
|
US8680275, 181
Show/Hide
|
C18H20BrN5O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0507168
|
US8680275, 186
Show/Hide
|
C20H21FN8O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0510194
|
US8680275, 89
Show/Hide
|
C19H20F3N5O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0510195
|
US8680275, 107
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0550292
|
US8680275, 162
Show/Hide
|
C21H24N8O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0553891
|
US8680275, 103
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0553892
|
US8680275, 109
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0556852
|
US8680275, 106
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0557759
|
US8680275, 163
Show/Hide
|
C21H24N8O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0486425
|
N-[(2-chloro-6-fluorophenyl)methyl]-N-methyl-2-[2-(5-methylfuran-2-yl)-1,3-thiazol-4-yl]acetamide
Show/Hide
|
C18H16ClFN2O2S
|
1
|
| 1 |
Ki = 11748.98 nM
|
|
|
|
CP0561094
|
(2-benzylphenyl)-[4-[[2-(furan-2-yl)-1,3-thiazol-4-yl]methyl]piperazin-1-yl]methanone
Show/Hide
|
C26H25N3O2S
|
1
|
| 1 |
Ki = 14791.08 nM
|
|
|
|
CP0567518
|
5-chloro-N-methyl-N-(2-naphthalen-1-ylethyl)-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C19H17ClN2O2
|
1
|
| 1 |
Ki = 14791.08 nM
|
|
|
|
CP0571880
|
pyridin-3-ylmethyl 2-(3-methoxyphenyl)-5-methyl-1H-imidazole-4-carboxylate
Show/Hide
|
C18H17N3O3
|
1
|
| 1 |
Ki = 14791.08 nM
|
|
|
|
CP0570650
|
1-[(3R)-3-[(2-methylphenoxy)methyl]piperidin-1-yl]-3-(3-pyridin-2-yl-1,2,4-oxadiazol-5-yl)propan-1-one
Show/Hide
|
C23H26N4O3
|
1
|
| 1 |
Ki = 15135.61 nM
|
|
|
|
CP0444233
|
5-[5-[(4-methylphenyl)methylsulfanylmethyl]furan-2-yl]-3-pyridin-2-yl-1,2,4-oxadiazole
Show/Hide
|
C20H17N3O2S
|
1
|
| 1 |
Ki = 15488.17 nM
|
|
|
|
CP0305849
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)acetamide
Show/Hide
|
C18H17N5O3S2
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0376074
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-phenylethyl)acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0389406
|
N-[3-(1,3-benzodioxol-5-yl)phenyl]-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C27H22N4O5S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0389407
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C14H14N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0389413
|
N-(3-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0403957
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
Show/Hide
|
C17H15N5O3S2
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0403958
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
Show/Hide
|
C17H16N6O3S2
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0417765
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methoxyphenyl)acetamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0489662
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-pyridin-3-ylacetamide
Show/Hide
|
C27H25N5O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0489663
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-piperazin-2-ylacetamide
Show/Hide
|
C26H30N6O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0489667
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-phenylacetamide
Show/Hide
|
C20H18N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0493789
|
N-(2,3-dihydroindol-1-yl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H21N5O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0493790
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxyphenyl)acetamide
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0493791
|
N-(2-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0505375
|
N-(2,3-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0508126
|
N-(2,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0520084
|
N-(4-fluorophenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C20H17FN4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0520085
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methylphenyl)acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0522128
|
2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-methylphenyl)acetamide
Show/Hide
|
C21H20N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0522129
|
N-(2,6-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C22H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0522130
|
N-butan-2-yl-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
Show/Hide
|
C18H22N4O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0522131
|
N-(3,5-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-(2-methylfuran-3-yl)-1,2,4-triazol-3-yl]sulfanyl]-N-pyridin-2-ylacetamide
Show/Hide
|
C27H25N5O3S
|
1
|
| 1 |
Ki > 15848.93 nM
|
|
|
|
CP0465679
|
N-[(1S)-1-(4-fluorophenyl)ethyl]-N-methyl-2-[2-(5-methylfuran-2-yl)-1,3-thiazol-4-yl]acetamide
Show/Hide
|
C19H19FN2O2S
|
1
|
| 1 |
Ki = 16982.44 nM
|
|
|
|
CP0570912
|
(3E)-3-[(4-morpholin-4-ylphenyl)methylidene]-1-phenylindol-2-one
Show/Hide
|
C25H22N2O2
|
1
|
| 1 |
Ki = 17782.79 nM
|
|
|
|
CP0486426
|
[(2R)-2-(2,4-dimethoxyphenyl)pyrrolidin-1-yl]-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]methanone
Show/Hide
|
C27H27N3O4
|
1
|
| 1 |
Ki = 20892.96 nM
|
|
|
|
CP0548166
|
(E)-3-(3-fluorophenyl)-1-[9-[[(2R)-oxan-2-yl]methoxy]-7-pyridin-3-yl-3,5-dihydro-2H-1,4-benzoxazepin-4-yl]prop-2-en-1-one
Show/Hide
|
C29H29FN2O4
|
1
|
| 1 |
Ki = 21379.62 nM
|
|
|
|
CP0465675
|
5-(5-phenyl-1H-pyrazol-4-yl)-1-(pyridin-4-ylmethyl)-4H-imidazo[4,5-c]pyrazole
Show/Hide
|
C19H15N7
|
1
|
| 1 |
Ki = 24547.09 nM
|
|
|
|
CP0575217
|
(2-oxo-1-phenyl-5,6,7,8-tetrahydroquinolin-4-yl) 4-methoxybenzoate
Show/Hide
|
C23H21NO4
|
1
|
| 1 |
Ki = 24547.09 nM
|
|
|
|
CP0561714
|
N-cyclopropyl-N-[(4-fluorophenyl)methyl]-3-(2-oxopyrrolidin-1-yl)benzamide
Show/Hide
|
C21H21FN2O2
|
1
|
| 1 |
Ki = 32359.37 nM
|
|
|
|
CP0553268
|
5-[[2-[(2-fluorophenyl)methoxy]naphthalen-1-yl]methylidene]-1,3-diazinane-2,4,6-trione
Show/Hide
|
C22H15FN2O4
|
1
|
| 1 |
Ki = 33113.11 nM
|
|
|
|
CP0573450
|
N-(2,6-dimethylphenyl)-4-(5,7-dioxopyrrolo[3,4-b]pyridin-6-yl)butanamide
Show/Hide
|
C19H19N3O3
|
1
|
| 1 |
Ki = 33884.42 nM
|
|
|
|
CP0486445
|
(3-chloro-4-fluoro-1-benzothiophen-2-yl)-[4-(furan-2-ylmethyl)piperazin-1-yl]methanone
Show/Hide
|
C18H16ClFN2O2S
|
1
|
| 1 |
Ki = 43651.58 nM
|
|
|
|
CP0552031
|
US9029364, 11
Show/Hide
|
C19H20N6O2S
|
1
|
| 1 |
Ki > 1259 nM
|
|
|
|
CP0385165
|
US9029364, 14
Show/Hide
|
C20H21ClN6O3S
|
1
|
| 1 |
Ki > 1291 nM
|
|
|
|
CP0459015
|
US9029364, 9
Show/Hide
|
C21H20N6O2S
|
1
|
| 1 |
Ki > 1291 nM
|
|
|
