Brief Information of the Compound and Protein
Compound Name
 Compound Info 
9-(4,6-dimethylpyrimidin-2-yl)-2-[(5-phenyl-2H-triazol-4-yl)methyl]-2,9-diazaspiro[5.5]undecan-1-one
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 PubChem ID
CID: 72704099
Canonical SMILES
Cc1cc(C)nc(n1)N1CCC2(CCCN(Cc3[nH]nnc3-c3ccccc3)C2=O)CC1
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Compound Formula C24H29N7O
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 707.95 nM
   TI
   LI
   LO
   TS