Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2R)-2-(2,4-dimethoxyphenyl)pyrrolidin-1-yl]-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]methanone
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 PubChem ID
CID: 40954109
Canonical SMILES
COc1ccc([C@H]2CCCN2C(=O)c2ccc(OCc3cn4ccccc4n3)cc2)c(OC)c1
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Compound Formula C27H27N3O4
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 20892.96 nM
   TI
   LI
   LO
   TS