Brief Information of the Compound and Protein
Compound Name
N-[(Z)-anthracen-9-ylmethylideneamino]-6-methyl-5H-[1,2,4]triazino[5,6-b]indol-3-amine
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PubChem ID
CID: 6418917
Canonical SMILES
Cc1cccc2c3nnc(N\N=C/c4c5ccccc5cc5ccccc45)nc3[nH]c12
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Compound Formula C25H18N6
Compound Structure
Protein Name
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
2
Ki = 1100 nM
   TI
   LI
   LO
   TS
3
Ki = 16200 nM
   TI
   LI
   LO
   TS