Brief Information of the Compound and Protein
Compound Name
[(2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrrolidin-1-yl]-[4-(imidazo[1,2-a]pyridin-2-ylmethoxy)phenyl]methanone
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PubChem ID
CID: 41037884
Canonical SMILES
O=C(N1CCC[C@@H]1c1ccc2OCCOc2c1)c1ccc(OCc2cn3ccccc3n2)cc1
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Compound Formula C27H25N3O4
Compound Structure
Protein Name
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS