Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-ethyl-5-fluoro-N-[(2S)-1-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]propan-2-yl]-2-pyrimidin-2-ylbenzamide
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 PubChem ID
CID: 72700265
Canonical SMILES
CCN([C@@H](C)Cc1noc(n1)-c1ccc(F)cc1)C(=O)c1cc(F)ccc1-c1ncccn1
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Compound Formula C24H21F2N5O2
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.58 nM
   TI
   LI
   LO
   TS