Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8530648, 200
    Show/Hide
 PubChem ID
CID: 67251476
Canonical SMILES
O=C1CCCC2(CCN(CC2)c2cnc3ccccc3n2)N1Cc1ccccc1
    Show/Hide
Compound Formula C24H26N4O
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 1479.11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1443 nM