Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S)-1-[2-(1H-benzimidazol-2-ylsulfanyl)acetyl]-N-(4-phenylphenyl)pyrrolidine-2-carboxamide
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 PubChem ID
CID: 15949702
SID: 22421114
Canonical SMILES
O=C(CSc1nc2ccccc2[nH]1)N1CCC[C@H]1C(=O)Nc1ccc(cc1)-c1ccccc1
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Compound Formula C26H24N4O2S
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 2300 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Activity = 1700 nM
   TI
   LI
   LO
   TS