Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(2,6-dimethoxyphenyl)-1-[[2-(1,3-thiazol-2-yl)pyridin-4-yl]methyl]piperidin-2-one
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 PubChem ID
CID: 69081742
Canonical SMILES
COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccnc(c1)-c1nccs1
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Compound Formula C22H23N3O3S
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 19 nM
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