Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3aS,4R,7aS)-4-methyl-2-[3-[(2S)-1-(4-methylphenyl)-1-oxopropan-2-yl]oxyphenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione
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Canonical SMILES
C[C@H](Oc1cccc(c1)N1C(=O)[C@H]2CC=C[C@@H](C)[C@@H]2C1=O)C(=O)c1ccc(C)cc1
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Compound Formula C25H25NO4
Compound Structure
Protein Name
 Protein Info 
Orexin/Hypocretin receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Orexin receptor
Uniprot ID
O43613
Gene Name
HCRTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 7762.47 nM
   TI
   LI
   LO
   TS